D. H. C. Williams
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Philosophy Biology
D. H. C. Williams's Degrees
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)D. H. C. Williams's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Increased osteoclast development after estrogen loss: mediation by interleukin-6. (1992) (719)
- 17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens. (1992) (690)
- Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats. (1994) (651)
- Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells. (1981) (365)
- Cytoplasmic inclusion bodies in Escherichia coli producing biosynthetic human insulin proteins. (1982) (295)
- The serotonin transporter: a primary target for antidepressant drugs (1998) (262)
- Truncation of limonene synthase preprotein provides a fully active 'pseudomature' form of this monoterpene cyclase and reveals the function of the amino-terminal arginine pair. (1998) (257)
- Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow. Evidence for autonomy from factors released during bone resorption. (1998) (203)
- The development of ruthenium(ii) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications. (2017) (201)
- Membrane cholesterol modulates serotonin transporter activity. (2001) (171)
- The metabolism of tryptophan. 2. The metabolism of tryptophan in patients suffering from cancer of the bladder. (1956) (153)
- Blanching of vegetables for freezing: which indicator enzyme to choose (1986) (146)
- Comparison of seven different heterologous protein expression systems for the production of the serotonin transporter. (2003) (136)
- The Reproductive System, Embryonic Development, Larval Development and Metamorphosis of the Sea Urchin Heliocidaris erythrogramma (Val.) (Echinoidea : Echinometridae) (1975) (131)
- Luminescent ruthenium(II) polypyridyl functionalized gold nanoparticles; their DNA binding abilities and application as cellular imaging agents. (2011) (131)
- Sequential coccolith morphogenesis in Hymenomonas carterae. (1971) (122)
- The Activity of the Enzymes Sulphatase and β-Glucuronidase in the Urine, Serum and Bladder Tissue (1955) (110)
- Activation of NF-kappa B and induction of vascular cell adhesion molecule-1 and intracellular adhesion molecule-1 expression in human glial cells by IL-1. Modulation by antioxidants. (1994) (110)
- Thrombin-induced platelet aggregation is mediated by a platelet plasma membrane-bound lectin. (1978) (104)
- Evaluation of peroxyoxalate chemiluminescence for determination of enzyme generated peroxide. (1976) (100)
- Heterologous expression and characterization of a "Pseudomature" form of taxadiene synthase involved in paclitaxel (Taxol) biosynthesis and evaluation of a potential intermediate and inhibitors of the multistep diterpene cyclization reaction. (2000) (96)
- Comparison of concentrations of some trace, bulk, and toxic metals in the hair of normal and dyslexic children. (1981) (93)
- Multiple forms and locations for the peripheral-type benzodiazepine receptor. (1996) (87)
- Fibrinogen is the receptor for the endogenous lectin of human platelets (1981) (83)
- Silver–zinc: status of technology and applications (1999) (82)
- Interleukin-1 activates transcription factor NF kappa B in glial cells. (1993) (81)
- Synthesis, spectroscopic and biological studies of a fluorescent Pt(II) (terpy) based 1,8-naphthalimide conjugate as a DNA targeting agent. (2013) (79)
- Isolation and characterization of insulin-like growth factor-II from human bone. (1988) (77)
- Comparison of ground and aerial ultra-low volume applications of malathion against Aedes aegypti in Santo Domingo, Dominican Republic. (1990) (76)
- Plasma vitamin A in patients with bronchial carcinoma. (1976) (74)
- Sodium ion-dependent transporters for neurotransmitters: a review of recent developments. (1994) (73)
- Two subcellular locations for peripheral-type benzodiazepine acceptors in rat liver. (1990) (70)
- In vitro pharmacology of cryptophycin 52 (LY355703) in human tumor cell lines (1999) (70)
- Synthesis, Biological Activity, and SARs of Pyrrolobenzoxazepine Derivatives, a New Class of Specific “Peripheral-Type” Benzodiazepine Receptor Ligands1 (1996) (69)
- Ultrasensitive near-IR fluorescence detection for capillary gel electrophoresis and DNA sequencing applications. (1995) (68)
- Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells. (2015) (67)
- Photophysical and biological investigation of novel luminescent Ru(II)-polypyridyl-1,8-naphthalimide Tröger's bases as cellular imaging agents. (2012) (62)
- Automated chemiluminescence method for determining the reduced form of nicotinamide adenine dinucleotide coupled to the measurement of lactate dehydrogenase activity. (1976) (61)
- The polarographic estimation of steroid hormones. 5. Determination of progesterone in blood. (1951) (60)
- Long-range changes in a protein antigen due to antigen-antibody interaction. (1992) (59)
- In vitro Evidence of Neutral Collagenase Activity in an Invasive Mammalian Tumour (1969) (59)
- Enzyme Activity in Relation to Cancer (1957) (58)
- Luminescent Lanthanide Cyclen-Based Enzymatic Assay Capable of Diagnosing the Onset of Catheter-Associated Urinary Tract Infections Both in Solution and within Polymeric Hydrogels. (2017) (57)
- Mechanism of monoterpene cyclization: stereochemical aspects of the transformation of noncyclizable substrate analogs by recombinant (-)-limonene synthase, (+)-bornyl diphosphate synthase, and (-)-pinene synthase. (2001) (57)
- The polarographic estimation of steroid hormones. VI. Determination of individual adrenocortical hormones in human peripheral blood. (1953) (57)
- Platelet plasma membrane lectin activity. (1977) (56)
- Identification of Tubulin as the Molecular Target of Proapoptotic Pyrrolo-1,5-benzoxazepines (2006) (56)
- Intramolecular proton transfer in the cyclization of geranylgeranyl diphosphate to the taxadiene precursor of taxol catalyzed by recombinant taxadiene synthase. (2000) (54)
- Enzyme Activity in Relation to Cancer (1957) (51)
- Polar lobe formation and cytokinesis in fertilized eggs of Ilyanassa obsoleta. I. Ultrastructure and effects of cytochalasin B and colchicine. (1974) (51)
- On-line fluorescence lifetime determinations in capillary electrophoresis. (1995) (51)
- Glycosidase activated release of fluorescent 1,8-naphthalimide probes for tumor cell imaging from glycosylated 'pro-probes'. (2016) (50)
- Pyrrolo[1,5]benzoxa(thia)zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target. (2005) (49)
- Insecticide susceptibility of Aedes aegypti from Santo Domingo, Dominican Republic. (1991) (48)
- The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. (1981) (48)
- Distribution, abundance, and seasonal activities of ticks collected from rodents and vegetation in South Carolina. (1998) (47)
- Pyrrolo-1,5-benzoxazepines induce apoptosis in HL-60, Jurkat, and Hut-78 cells: a new class of apoptotic agents. (2000) (47)
- Antiproliferative Action of Benzodiazepines in Cultured Brain Cells Is Not Mediated Through the Peripheral‐Type Benzodiazepine Acceptor (1989) (47)
- Isolation, Cultivation, and Characterization of Borrelia burgdorferi from Rodents and Ticks in the Charleston Area of South Carolina (2000) (47)
- Two cellular and subcellular locations for the peripheral-type benzodiazepine receptor in rat liver. (1996) (46)
- Peripheral-type benzodiazepine receptors. (1997) (45)
- “True” Antiandrogens—Selective Non-Ligand-Binding Pocket Disruptors of Androgen Receptor–Coactivator Interactions: Novel Tools for Prostate Cancer (2012) (44)
- Self-assembly of hybrid organic-inorganic polyoxovanadates: functionalised mixed-valent clusters and molecular cages. (2012) (44)
- Glucose oxidase chemiluminescence measurement of glucose in urine compared with the hexokinase method. (1976) (44)
- The antidepressants maprotiline and fluoxetine have potent selective antiproliferative effects against Burkitt lymphoma independently of the norepinephrine and serotonin transporters (2010) (44)
- Ultrasensitive near-infrared laser-induced fluorescence detection in capillary electrophoresis using a diode laser and avalanche photodiode. (1997) (44)
- The anomalous kinetics of coupled aspartate aminotransferase and malate dehydrogenase. Evidence for compartmentation of oxaloacetate. (1976) (41)
- Purification of porphobilinogen deaminase from Euglena gracilis and studies of its kinetics. (1981) (41)
- The effect of anti-cancer drugs on the plasma disposition of antipyrine and the biliary excretion of phenolphthalein in the rat. (1978) (40)
- The effects of diethylstilboestrol and castration on the nucleic acid and protein metabolism of rat prostate gland. (1967) (40)
- Subcellular distribution of testosterone in rat prostate and its possible relationship to nuclear ribonucleic acid synthesis. (1968) (39)
- Plasma and body lipids in patients with carcinoma of the breast. (1975) (39)
- BubR1 Is Required for a Sustained Mitotic Spindle Checkpoint Arrest in Human Cancer Cells Treated with Tubulin-Targeting Pyrrolo-1,5-Benzoxazepines (2008) (38)
- The serum levels of some trace and bulk elements in cancer patients. (1982) (38)
- Flexible estrogen receptor modulators: design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells. (2001) (37)
- Supramolecular approach to enantioselective DNA recognition using enantiomerically resolved cationic 4-amino-1,8-naphthalimide-based Tröger's bases. (2014) (37)
- Effects of estrogen and tamoxifen on serum osteocalcin levels in ovariectomized rats. (1991) (37)
- Barrier spraying to control the malaria vector Anopheles albimanus: laboratory and field evaluation in the Dominican Republic (1993) (37)
- Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor. (2004) (36)
- Target specific virtual screening: optimization of an estrogen receptor screening platform. (2007) (36)
- Quaternarized pdppz: synthesis, DNA-binding and biological studies of a novel dppz derivative that causes cellular death upon light irradiation. (2011) (36)
- Subcellular distribution of some folic acid-linked enzymes in rat liver. (1965) (35)
- The oxidation of tryptophan and some related compounds with persulphate. (1956) (35)
- A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin (2008) (34)
- Nucleic Acid Changes in Bacteroids of Rhizobium lupini During Nodule Development (1967) (33)
- Leucocyte ascorbic acid and urinary hydroxyproline levels in patients bearing breast cancer with skeletal metastases. (1974) (32)
- The estimation of tryptophan metabolites in the urine of patients with cancer of the bladder. (1955) (32)
- In vitro screening for anticonvulsant-induced teratogenesis in neural primary cultures and cell lines (1990) (32)
- In Vitro Neurotoxicity Testing (1994) (32)
- Synthesis, biological activity, and SARs of pyrrolobenzoxazepine derivatives, a new class of specific "peripheral-type" benzodiazepine receptor ligands. (1996) (31)
- Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin. (2009) (31)
- Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL (2004) (31)
- An in vitro assessment of the effect of cytotoxic drugs upon the intestinal absorption of nutrients in rats. (1979) (31)
- The novel tubulin-targeting agent pyrrolo-1,5-benzoxazepine-15 induces apoptosis in poor prognostic subgroups of chronic lymphocytic leukemia. (2009) (30)
- Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic myelogenous leukemia (CML) cells by bypassing the apoptotic suppressor bcr-abl. (2001) (30)
- Baseline data on Aedes aegypti populations in Santo Domingo, Dominican Republic. (1990) (29)
- Biosynthesis of vitamin B12: Structural studies on the corriphryins from and the link with sirohydrochlorin (1977) (29)
- Multiple Molecular Forms of Ficus glabrata Ficin. Their Separation and Relative Physical, Chemical, and Enzymatic Properties. (1969) (28)
- Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1,8-naphthalimide derived Tröger's bases. (2014) (28)
- Reduction in the amide hydrogen exchange rates of an anti-lysozyme Fv fragment due to formation of the Fv-lysozyme complex. (1997) (28)
- The subcellular location in rat kidney of the peripheral benzodiazepine acceptor. (1988) (28)
- Immunocytochemical demonstration of human proinsulin chimeric polypeptide within cytoplasmic inclusion bodies of Escherichia coli. (1983) (28)
- Synergistic inhibition of [3H]muscimol binding to calf-brain synaptic membranes in the presence of L-homocysteine and pyridoxal 5'-phosphate. A possible mechanism for homocysteine-induced seizures. (1983) (28)
- Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(II)-polypyridyl conjugates. (2015) (28)
- PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells (2010) (27)
- Nuclear and cytoplasmic localization of the beta-amyloid peptide (1-43) in transfected 293 cells. (1996) (27)
- Sanger DNA-sequencing reactions performed in a solid-phase nanoreactor directly coupled to capillary gel electrophoresis. (1998) (27)
- Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells (2010) (27)
- Plasminogen activator in cultured Lewis lung carcinoma cells measured by chromogenic substrate assay. (1980) (27)
- Testosterone metabolism in the rat ventral prostate. (1969) (26)
- The effect of chronic alcohol intake upon the hepatic microsomal carcinogen-activation system. (1978) (26)
- Quantitative electronic analysis of normal and transformed BHK21 fibroblast aggregation. (1977) (26)
- The effects of the peripheral-type benzodiazepine acceptor ligands, Ro 5-4864 and PK 11195, on mitochondrial respiration. (1992) (25)
- c-fos mRNA expression in rat cortical neurons during glutamate-mediated excitotoxicity. (2004) (25)
- The effect of ascorbic acid (vitamin C) on two tumor cell lines in culture. (1978) (25)
- Immunological studies on the rat peripheral-type benzodiazepine acceptor. (1991) (24)
- Luminescent ruthenium polypyridyl complexes with extended 'dppz' like ligands as DNA targeting binders and cellular agents. (2016) (24)
- Hydrolysis of peptide bonds of the oxidized B-chain of insulin by Endothia parasitica protease. (1972) (24)
- Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base-Ru(ii)-curcumin organometallic conjugate. (2018) (23)
- Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo (2010) (23)
- Bionomic studies of the Anopheles mosquitoes of Dajabon, Dominican Republic. (1990) (23)
- Kinetics of papain-catalyzed hydrolyses of neutral substrates. (1967) (23)
- Biosynthesis of porphyrins and related macrocycles. Part 10. Vitamin B12: biochemical derivation of cobyrinic acid from uroporphyrinogen III. Studies with corresponding ring c methyl heptacarboxylic prophyrinogen, and proof of seven intact methyl transfers. (1977) (23)
- STI-571 (Imatinib Mesylate) Enhances the Apoptotic Efficacy of Pyrrolo-1,5-Benzoxazepine-6, a Novel Microtubule-Targeting Agent, in Both STI-571-Sensitive and -Resistant Bcr-Abl-Positive Human Chronic Myeloid Leukemia Cells (2007) (22)
- Antiproliferative action of pyrrolobenzoxazepine derivatives in cultured cells: absence of correlation with binding to the peripheral-type benzodiazepine binding site. (1998) (22)
- The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL-induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells (2016) (22)
- The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status and inhibits breast tumour growth in vivo. (2005) (22)
- Physiological and pharmacological regulation of biological calcification. (1991) (21)
- Inhibition of late-stage autophagy synergistically enhances pyrrolo-1,5-benzoxazepine-6-induced apoptotic cell death in human colon cancer cells. (2013) (21)
- The biochemistry of aromatic amines; the resistance of some o-aminoaryl sulphates to hydrolysis by aryl sulphatases. (1956) (21)
- Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents. (2011) (20)
- Substrate retention of fractured retraction fibres during detachment of trypsinized BHK21 fibroblasts. (1977) (20)
- Levels of cholesterol, 11-hydroxycorticosteroids and progesterone in plasma from postmenopausal women with breast cancer. (1975) (20)
- Studies of enzyme-mediated reactions. Part VII. Stereospecific syntheses of tritium-labelled (2R)- and (2S)-dopamines: stereochemical course of hydroxylation of dopamine by dopamine beta-hydroxylase (E.C. 1.14.17.1). (1976) (20)
- Field evaluations in malaise and canopy traps of selected targets as attractants for tabanid species (Diptera: Tabanidae). (1993) (20)
- Vitamin A nutrition and its relationship with plasma cholesterol level in the patients with cancer. (1974) (20)
- The novel pyrrolo-1,5-benzoxazepine, PBOX-6, synergistically enhances the apoptotic effects of carboplatin in drug sensitive and multidrug resistant neuroblastoma cells. (2014) (19)
- The thiamine status of patients with cancer as determined by the red cell transketolase activity. (1974) (19)
- A colorimetric assay system for tetrahydrofolate dehydrogenase. (1968) (19)
- Virtual screening for the identification of novel nonsteroidal glucocorticoid modulators. (2010) (19)
- Characterization of cementum derived growth factor as an insulin-like growth factor-I like molecule. (1997) (19)
- Pushing the limit: synthesis, photophysical and DNA binding studies of a NIR-emitting Ru(II)-polypyridyl probe with 'light switch' behaviour. (2012) (19)
- The endogenous lectin of human platelets is an alpha-granule component. (1981) (19)
- The fate of intravenously injected folate in rats. (1965) (18)
- Polar lobe formation and cytokinesis in fertilized eggs of Ilyanassa obsoleta. II. Large bleb formation caused by high concentrations of exogenous calcium ions. (1974) (18)
- Chlorpromazine inhibits mitosis of mammalian cells. (1983) (18)
- Sequential treatment with flavopiridol synergistically enhances pyrrolo-1,5-benzoxazepine-induced apoptosis in human chronic myeloid leukaemia cells including those resistant to imatinib treatment. (2010) (17)
- Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents. (2009) (17)
- Characterization of the multiple forms of hydroxymethylbilane synthase from rat spleen. (1984) (17)
- 5-Hydroxytryptamine excretion in patients with carcinoma of the larynx and bronchus. (1956) (17)
- Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90. (2011) (17)
- Hepatic function assessed (in rats) during chemotherapy with some anti-cancer drugs. (1979) (17)
- Synthesis and antiproliferative action of a novel series of maprotiline analogues. (2014) (16)
- Rat liver uroporphyrinogen III synthase has similar properties to the enzyme from Euglena gracilis, including absence of a requirement for a reversibly bound cofactor for activity. (1988) (16)
- Malaria transmission potential by Anopheles mosquitoes of Dajabon, Dominican Republic. (1991) (15)
- Novel naphthoquinones from a Streptomyces sp. (1999) (15)
- The effect of ethanol ingestion on the erythrocyte antioxidant defence systems of rats. (1980) (15)
- Serum galactosyl transferase levels in patients with advanced cancer. (1982) (15)
- Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells (2016) (15)
- Emergency control of Aedes aegypti in the Dominican Republic using the Scorpion 20 ULV forced-air generator. (1994) (15)
- Immunocytochemical localization of plasminogen activator on porcine kidney cell strain: LLC-PK1 (LP100). (1979) (14)
- The novel pyrrolo-1,5-benzoxazepine, PBOX-21, potentiates the apoptotic efficacy of STI571 (imatinib mesylate) in human chronic myeloid leukaemia cells. (2009) (14)
- Ticks of South Carolina (Acari: Ixodoidea). (1999) (14)
- Synthesis, antiproliferative and pro-apoptotic activity of 2-phenylindoles. (2016) (14)
- Interleukin-1 and phorbol myristate acetate modulate the peripheral-type benzodiazepine receptor in lymphocytes and glial cells. (1993) (14)
- Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce cell cycle arrest and apoptosis in prostate cancer cells. (2010) (13)
- The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells. (2013) (13)
- Biosynthesis of the natural (type-III) porphyrins: proof that rearrangement occurs after head-to-tail bilane formation (1977) (13)
- Calmidazolium and other imidazole compounds affect steroidogenesis in Y1 cells: Lack of involvement of the peripheral-type benzodiazepine receptor (1997) (13)
- Oxidative stress induces apoptosis in C6 glioma cells: Involvement of mitogen-activated protein kinases and nuclear factor kappa B (2001) (13)
- The Microtubule-Targeting Agents, PBOX-6 [Pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and Paclitaxel, Induce Nucleocytoplasmic Redistribution of the Peptidyl-Prolyl Isomerases, Cyclophilin A and Pin1, in Malignant Hematopoietic Cells (2009) (13)
- Caspase-activated DNase (CAD)-independent oligonucleosomal DNA fragmentation in chronic myeloid leukaemia cells; a requirement for serine protease and Mn2+-dependent acidic endonuclease activity (2006) (12)
- Hexachlorocyclohexanes inhibit steroidogenesis in Y1 cells. Absence of correlation with binding to the peripheral-type benzodiazepine binding site. (1996) (12)
- Biosynthesis of vitamin B12: derivation of cobyrinic acid from uroporphyrinogen-III (1975) (11)
- 4-Amino-1,8-naphthalimide based fluorescent photoinduced electron transfer (PET) pH sensors as liposomal cellular imaging agents: The effect of substituent patterns on PET directional quenching (2019) (11)
- Survey of container-inhabiting mosquitoes in Clemson, South Carolina, with emphasis on Aedes albopictus. (1995) (11)
- Binding of benzodiazepines to blood platelets from various species. (1984) (11)
- Amylase, cellulase and protease activities in surface and gut tissues ofDendraster excentricus, Pisaster ochraceus andStrongylocentrotus droebachiensis (Echinodermata) (1991) (11)
- The effect of overcrowding stress on carcinogen-metabolizing enzymes of the rat. (1980) (11)
- Synthesis, Characterization, and Biological Profiling of Ruthenium(II)-Based 4-Nitro- and 4-Amino-1,8-naphthalimide Conjugates. (2020) (11)
- Penetration of ultra-low volume applied insecticide into dwellings for dengue vector control. (1992) (11)
- Lack of Effect of Methotrexate on Hepatic Regeneration (1965) (11)
- Biosynthesis of vitamin B12: evidence from double-labelling studies (13CD3) for intact incorporation of seven methyl groups (1976) (11)
- Purification and properties of the 3alpha-hydroxy steroid-dependent nicotinamide-adenine dinucleotide transhydrogenase of rat liver. (1963) (11)
- Improvements in an in-vitro assay for excitotoxicity by measurement of early gene (c-fos mRNA) levels (2005) (11)
- Kinetics of the interaction of sertraline with the human platelet plasma membrane 5-hydroxytryptamine carrier. (1988) (10)
- Basic N-interlinked imipramines show apoptotic activity against malignant cells including Burkitt's lymphoma. (2013) (10)
- Excretion of 5-hydroxyindole acetic acid and n1-methylnicotinamide in advanced cancer patients. (1973) (10)
- PK 11195 reduces the brain availability of lindane in rats and the convulsions induced by this neurotoxic agent. (1995) (10)
- Dual targeting of tumour cells and host endothelial cells by novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines (2009) (10)
- The effect of isolation stress on some hepatic drug and carcinogen metabolising enzymes in rats. (1980) (10)
- Regioselectivity of the insertion reactions of some aromatic diazo compound complexes with cyclomaltoheptaose. (1992) (10)
- Hydrolase (β-Glucanase, α-Glucanase, and Protease) Activity in Ariolimax columbianus (Banana Slug) and Arion ater (Garden Slug) (1997) (9)
- Tuluweckelia cernua , a new genus and species of stygobiont amphipod crustacean ( Hadziidae ) from anchialine caves on the Yucatan Peninsula in Mexico (9)
- Dissociation and catalysis in yeast hexokinase A. (1976) (9)
- The enzymic reduction of nicotinamide-adenine dinucleotide by 2-mercaptoethanol. (1965) (9)
- Multiple forms of calmodulin on sodium dodecyl sulphate/polyacrylamidegel electrophoresis (1984) (9)
- Water-soluble amphiphilic ruthenium(ii) polypyridyl complexes as potential light-activated therapeutic agents. (2020) (9)
- Microtubule-targeting-compound PBOX-15 radiosensitizes cancer cells in vitro (2011) (9)
- Stabilization of the peripheral-type benzodiazepine acceptor by specific phospholipids. (1992) (9)
- Plasminogen activation transforms the morphology of quiescent 3T3 cell monolayers and initiates growth. (1979) (9)
- Ascorbic acid therapy for the relief of bone pain in Paget's disease. (1978) (8)
- Inter‐relationships of nutrition and cancer (1973) (8)
- Visible light inhibits growth of Chinese hamster ovary cells. (1983) (8)
- Effect of Alkyl Chain Length on the Photophysical, Photochemical, and Photobiological Properties of Ruthenium(II) Polypyridyl Complexes for Their Application as DNA-Targeting, Cellular-Imaging, and Light-Activated Therapeutic Agents (2021) (8)
- The effect of chloroform ingestion on the growth of some murine tumours. (1979) (8)
- Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents. (2001) (8)
- Platelet 5‐HT uptake in post‐stroke depression (1990) (8)
- Lewis Lung Carcinoma: Selecting Metastatic Variants (1980) (7)
- The activity of the enzymes sulphatase and glucuronidase in the urine of normal and cancer patients. (1954) (7)
- The correlation between plasminogen activator-stimulated DNA synthesis and cell morphology in 3T3 cells. (1978) (7)
- Urinary hydroxyproline and plasma mucoprotein as an indication of the presence of bone metastases. (1974) (7)
- Enzymic formation of the type-III prophyrin macrocycle from unrearranged AP·AP pyrromethane (1977) (7)
- The effect of castration on the ribonucleic acid metabolism of an experimental prostatic tumour. (1966) (7)
- Automatic cell changer for enzyme assay by recording fluorometry and its use with dihydrofolic reductase. (1965) (7)
- Antisera Raised Against the Drug Imipramine (1987) (7)
- Morphological changes in frog pronephric cell surfaces after transformation by herpes virus. (1976) (7)
- The reception of androgens in the rat ventral prostate. (1969) (7)
- [195] Dihydrofolic reductase (5,6,7,8-tetrahydrofolate: NADP oxidoreductase, EC 1.5.1.3) (1971) (7)
- Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines. (2010) (7)
- Effects of feeding and starvation on proteolytic and tryptic activities in pyloric caecal tissues and duct fluids of the seastar Pisaster ochraceus (1985) (6)
- The Metabolism of Testosterone in the Prostate (1971) (6)
- A monoclonal anti-imipramine antibody with antidepressant binding properties similar to the muscarinic receptor. (1990) (6)
- Endothelin‐1 Increases Arachidonic Acid Release in C6 Glioma Cells Through a Potassium‐Modulated Influx of Calcium (1996) (6)
- The Peripheral‐Type Benzodiazepine Receptor Is Present in Astrocytes but Is Not a Primary Site of Action for Convulsants/Anticonvulsants (1994) (6)
- The occurrence and distribution of digestive enzymes in the pyloric caecum of the purple starfish Pisaster ochraceus. (1975) (6)
- Induction of apoptosis in oral squamous carcinoma cells by pyrrolo-1,5-benzoxazepines. (2015) (6)
- The influence of zinc status on the anti-Lewis lung tumour activity of cisplatin and gallium. (1981) (6)
- The transplantation of chemically induced steroid sensitive mammary tumours. (1965) (6)
- DIEL PERIODICITY OF OVIPOSITION AND SOIL MOISTURE PREFERENCE OF PSOROPHORA COLUMBIAE1,2 (1986) (6)
- First report of Ixodes (Ixodes) minor Neumann (Acari: Ixodidae) from South Carolina. (1992) (6)
- Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine–induced apoptosis in neuroblastoma cells (2016) (6)
- Chromosomal examination of various cell clones (in vitro) derived from a DMBA (7-12 dimethyl-alpha-benzanthracene)-induced male rat breast tumour. (1973) (6)
- Malathion resistance in mosquitoes from Charleston and Georgetown counties of coastal South Carolina. (1994) (6)
- Chronotropic effect of tyramine on rat heart cells cultured with sympathetic neurons. (1978) (6)
- The effect of chronic ethanol intake on the growth and spread of some murine tumors. (1978) (6)
- The effect of prolonged ethanol intake on some carcinogen-activating enzymes in mice. (1979) (5)
- Isolation, purification and partial characterization of four digestive proteases from the purple seastar Pisaster ochraceus (1988) (5)
- Effects of controlled burning on Aedes taeniorhynchus eggs in an abandoned rice impoundment in South Carolina. (1990) (5)
- A simple rapid purification scheme for hydroxymethylbilane synthase from human erythrocytes. (1988) (5)
- The role of lysosomal enzymes in malignant growth. (1968) (5)
- Correlation between tumour size, metastatic spread and galactosyl transferase activity in cyclophosphamide-treated mice bearing the Lewis lung carcinoma. (1979) (5)
- In vitro screening for anticonvulsant-induced teratogenesis: Structure-activity relationships in the barbiturate and branched chain carboxylic acid classes. (1991) (5)
- Studies of the susceptibility of Anopheles albimanus and Anopheles vestitipennis from Dajabon, Dominican Republic, to insecticides. (1990) (4)
- The recovery of liver tetrahydrofolate dehydrogenase activity from inhibition by methotrexate. (1969) (4)
- Biosynthesis of porphyrins and related macrocycles. Part 15. Chemical and enzymic formation of uroporphyrinogen isomers from unrearranged aminomethylpyrromethane: separation of isomeric coproporphyrin esters (1982) (4)
- Different Specificities for Taurine Analogues and their Target Sites in Brain (1997) (4)
- On the possible involvement of an anhydride intermediate in papain-catalyzed hydrolyses. (1968) (4)
- Reconstitution of the rat brain serotonin transporter. (1995) (4)
- Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt’s Lymphoma (2020) (4)
- In vivo Effect of an Invasive Malignant Rat Tumour on Cartilage (1967) (4)
- The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15 (2016) (4)
- The inhibition of 3-alpha-hydroxy steroid-activated nicotinamide-adenine dinucleotide (phosphate) transhydrogenase by some antimetabolic compounds. (1964) (3)
- The production and secreton of digestive enzymes in the purple seastar Pisaster ochraceus (1975) (3)
- Enzyme induction by steroid hormones with reference to cancer. (1975) (3)
- Some metabolic functions of liver in patients with advanced non-hepatic cancer. (1974) (3)
- Biosynthesis of porphyrins and related macrocycles. Part 11. Studies on biosynthesis of the phytyl chain of chlorophyll a by use of carbon-13 (1977) (3)
- Stereochemical course of hydroxylation of dopamine by dopamine-β-hydroxylase (EC1.14.17.1) (1974) (3)
- Use of inverted intestinal sacs to assess the effect of gastrointestinal insult on carcinogen absorption. (1981) (3)
- Dithiothreithol promotes a higher affinity state of the serotonin transporter for the tricyclic antidepressant, imipramine. (1995) (3)
- Multiple affinity states for [3H]imipramine binding sites on human platelet membranes. (1984) (3)
- Effect of combined immunosuppressive drug therapy on small intestinal nutrient transport in the rat. (1999) (3)
- THE INHIBITION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE-LINKED 3-ALPHA-HYDROXY STEROID DEHYDROGENASE BY CERTAIN ANTIMETABOLIC DRUGS. (1965) (3)
- Effects of methotrexate and phenobarbital on the hepatic microsomal drug-metabolizing enzymes in normal rat. (1975) (3)
- Testosterone metabolism in the rat ventral prostate. (1968) (3)
- 'High-affinity' peripheral-type benzodiazepine-binding sites. (1987) (3)
- Selected nitrostyrene compounds demonstrate potent activity in chronic lymphocytic leukaemia cells, including those with poor prognostic markers. (2019) (3)
- The relationship between 3 α-hydroxysteroid nicotinamide nucleotide coenzyme transhydrogenation and β-glucuronidase in regenerating rat liver (1964) (2)
- The enzymic hydrolysis of derivatives of aminophenols. (1955) (2)
- lnterleukin-1 activates transcription factor NFKB in glial cells (2005) (2)
- Flit-gun sprayer characteristics. (1998) (2)
- The presence of a substance with hydrogen transporting properties in some samples of methotrexate. (1968) (2)
- A simple technique for the separation and estimation of 3H-labelled androgen metabolites. (1969) (2)
- THE EFFECT OF TRANSPLANTED MAMMARY TUMOURS ON THE CALCIUM BALANCE OF THE RAT. (1964) (2)
- Probing the platelet plasma-membrane 5-hydroxytryptamine transporter. (1991) (2)
- Enrichment of rat liver and kidney ‘peripheral-type’ benzodiazepine-binding sites in plasma membrane-derived fractions (1986) (2)
- Combined therapy with ascorbic acid and calcitonin for the relief of bone pain in Paget's disease. (1981) (2)
- β-glucanase activity in the seastar Pisaster ochraceus (1995) (2)
- Operational note indoor low-volume spray trials: handheld equipment evaluation. (2002) (2)
- A new method of testing Bacillus thuringiensis var. israelensis (H-14) formulations on Aedes taeniorhynchus in an abandoned rice impoundment in South Carolina. (1989) (2)
- Effect of chloroform ingestion on some carcinogen-metabolising enzyme systems of rats (1979) (2)
- In vitro HIV infection of primate lymphocytes. (1990) (1)
- Selective Induction of Apoptosis by PBOX-6 in Leukemia Cells occurs via the JNK Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL (2004) (1)
- Stereochemistry of the Methyl→Methylene Elimination in the Enzyme‐Catalyzed Cyclization of Geranyl Diphosphate to (4S)‐Limonene. (1998) (1)
- Pyrrolo-1,5-Benzoxazepines Induce Apoptosis in Chronic Myeloid Leukemia (CML) Cells by Bypassing the Apoptotic Suppressor BCR-ABL (2001) (1)
- Effect of suramin (Bayer 205) on hepatic microsomal cytochromes P-450, b 5 , and demethylation activity in rats. (1973) (1)
- The effect of triton X-100 on bovine brain synaptic membranes (1988) (1)
- Blood values of some vitamins in long-stay psycho-geriatric patients. (1976) (1)
- Solubilization of human platelet plasma membrane 5-hydroxytryptamine carrier with retention of native properties (1986) (1)
- Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line. (2001) (1)
- Methotrexate and alopecia. (1973) (1)
- Gradient Elution Chromatography of Corticosteroids in Human Blood (2008) (1)
- Fibrinolysis in lung cancer. (1978) (1)
- Influence of age on isolation stress‐stimulated carcinogen‐metabolizing enzymes of rats (1981) (1)
- A simplified microassay of transketolase in human blood. (1974) (1)
- Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents (2001) (1)
- The ‘Thiamin-Sparing’ Effect of Ascorbic Acid (1976) (1)
- Interleukin-6 neutralizing antibody administration prevents osteoclastogenic response to ovariectomy in the mouse (1992) (1)
- Proceedings: Urinary hydroxyproline and leucocyte ascorbic acid levels in patients bearing breast tumour with skeletal metastases. (1974) (1)
- BASELINE DATA ON AEDE S AEGYPTI POPULATIONS IN SANTO DOMINGO , DOMINICAN REPUBLIC 1 (2004) (0)
- HORMONE-SENSITIVITY OF PYRIDINE NUCLEOTIDE TRANSHYDROGENASES IN NORMAL AND MALIGNANT TISSUE (1960) (0)
- BTONOMIC STUDIES OF TIIF " ANOPHETES MOSQUITOES OF DAJABON , DOMINICAN REPUBLIC 1 (2004) (0)
- SERT biosynthesis and the problems of overexpression for structural studies (2001) (0)
- Prognostic Subgroups of Chronic Lymphocytic Leukemia Pyrrolo-1 , 5-Benzoxazepine-15 Induces Apoptosis in Poor The Novel Tubulin-Targeting Agent (2009) (0)
- Recurrent and Metastatic Oncological Diseases (1974) (0)
- THE SELECTION AND TRANSPLANTATION OF HORMONE SENSITIVE TUMOURS (1965) (0)
- Purification and properties of calmodulin-activated phosphodiesterase from bovine brain (1987) (0)
- PENETRATIoN oF ULV Spnev rNro DwELLINGS PENETRATION OF ULTRA-LOW VOLUME APPLIED INSECTICIDE INTO DWELLINGS FOR DENGUE VECTOR CONTROL1 (2004) (0)
- Partial purification of the human platelet 5-HT transporter and crossreactivity with antibodies to the rat brain GABA transporter (1992) (0)
- 68 The Biochemistry of Aromatic Amines (2005) (0)
- Simultaneous application of adulticide and larvicide for mosquito control using the Scorpion 20 ULV forced air generator (1994) (0)
- THE INHIBITION OF TWO STEROID-ACTIVATED NICOTINAMIDE-ADENINE DINUCLEOTIDE (PHOSPHATE) TRANSHYDROGENASES BY FOLIC ACID AND FOLIC ACID ANTIMETABOLITES. (1965) (0)
- Depolarising levels of KCl inhibit endothelin-1-mediated release of arachidonic acid in rat C6 glioma cells. (1995) (0)
- Estimation of Individual Adrenocortical Hormones in Human Peripheral Blood (2008) (0)
- Production of rabbit anti-imipramine antibodies (1987) (0)
- peripheral-type benzodiazepine acceptor (2005) (0)
- Quaternarized pdppz: Synthesis, DNA-Binding and Biological Studies of a Novel dppz Derivative (I) that Causes Cellular Death upon Light Irradiation. (2011) (0)
- Abstract #399: The antidepressants fluoxetine and maprotiline induce apoptosis and type-II autophagic-programmed cell death in Burkitt\#8217;s lymphoma in vitro independently of SERT and NET (2009) (0)
- Subject Index, Vol. 20, 1976 (1976) (0)
- 281 Cancer: a less depressing outlook? Using antidepressants to induce autophagic programmed cell death in a resistant strain of Burkitt's lymphoma (2010) (0)
- Molecular studies on the peripheral-type benzodiazepine acceptor. (1992) (0)
- Using Enantiomerically Resolved Cationic 4 ‐ Amino-1 , 8-3 naphthalimide-Based Tröger ’ s Bases (2014) (0)
- Books Received / Book Reviews (1982) (0)
- Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine d ] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH 2 -Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl- XL (2004) (0)
- Partial purification of the human platelet 5-HT transporter and crossreactivity with antibodies to the rat brain GABA transporter (1992) (0)
- Contents, Vol. 20, 1976 (1974) (0)
- The effect of chloroform inhalation on hepatic glucuronidation and de-glucuronidation mechanisms. (1980) (0)
- The investigation of metastasis of endocrine tumours in bone. (1965) (0)
- Steroid Hormones and Cancer (1977) (0)
- Evidence for the presence of a trypsinogen-like zymogen in the tissues of the sea star Pisaster ochraceus (1982) (0)
- Identification of novel ligands for the peripheral-type benzodiazepine receptor. (1995) (0)
- The effect of oophorectomy on the ribonucleic acid metabolism of a transplantable uterine tumour. (1965) (0)
- Quaternarized pdppz; a novel dppz derivative that causes cellular deathupon light irradiation: Synthesis, DNA-binding and biological studies (2011) (0)
- 831: Induction of apoptosis by pyrrolo-1,5-benzoxazepines in oral squamous carcinoma cells (2014) (0)
- Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic B-lymphoid malignancies (2006) (0)
- Inhibition of brain cell proliferation by benzodiazepines (1986) (0)
- THE RELATIONSHIP BETWEEN 3 ALPHA-HYDROXYSTEROID NICOTINAMIDE NUCLEOTIDE COENZYME TRANSHYDROGENATION AND BETA-GLUCURONIDASE IN REGENERATING RAT LIVER. (1964) (0)
- Acid Changes in Bacteroids of Rhizobium Zupini During Nodule Development (2008) (0)
- Synthesis and in vitro toxicity of 4-MTA , its characteristic clandestine synthesis byproducts and related sulphur substituted α-alkylthioamphetamines (2010) (0)
- A novel microtubule depolymerization agent, PBOX-15, induces apoptosis in non-proliferating chronic lymphocytic leukemia cells ex vivo. (2007) (0)
- 933 AN IN VITRO INVESTIGATION OF THE CYTOTOXIC AND RADIO-SENSITISING PROPERTIES OF A NOVEL MICRO- TUBULE TARGETING AGENT, PBOX-15, IN HYPOXIC PROSTATE CANCER CELL LINES (2011) (0)
- The University of Texas System Cancer Center M.D. Anderson Hospital and Tumor Institute (1982) (0)
- The design of photo-affinity labels for the characterisation of the 5-hydroxytryptamine transporter on human platelet membranes. (1991) (0)
- Towards Overexpression of the Serotonin Transporter (1997) (0)
- Modulation of the peripheral-type benzodiazepene acceptor by IL1 and PMA (1992) (0)
- andCastration on theNucleic Acid andProtein Metabolism ofRatProstate Gland (1967) (0)
- Retraction notice to “PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines” [Eur. J. Pharmacol. 714(1–3) (2013) 379–387]. (2014) (0)
- STEREOCHEMICAL COURSE OF HYDROXYLATION OF DOPAMINE BY DOPAMINE-BETA-HYDROXYLASE (EC1.14.17.1) (1974) (0)
- Modulation of the serotonin transporter by membrane cholesterol (2001) (0)
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