D. D. H. Thomas
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D. D. H. Thomasphilosophy Degrees
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D. D. H. Thomasbiology Degrees
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Physiology
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Philosophy Biology
D. D. H. Thomas's Degrees
- PhD Biochemistry University of California, Berkeley
- Doctorate Medicine University of California, San Francisco
Why Is D. D. H. Thomas Influential?
(Suggest an Edit or Addition)D. D. H. Thomas's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The biological lifetime of nitric oxide: implications for the perivascular dynamics of NO and O2. (2001) (627)
- Accelerated reaction of nitric oxide with O2 within the hydrophobic interior of biological membranes. (1998) (569)
- Mechanochemical coupling in actomyosin energy transduction studied by in vitro movement assay. (1990) (491)
- Orientation of spin-labeled myosin heads in glycerinated muscle fibers. (1980) (252)
- Mutation and phosphorylation change the oligomeric structure of phospholamban in lipid bilayers. (1997) (174)
- Penetration of endothelial cell monolayers by Borrelia burgdorferi (1989) (168)
- Treponema pallidum invades intercellular junctions of endothelial cell monolayers. (1988) (167)
- Electron paramagnetic resonance reveals age-related myosin structural changes in rat skeletal muscle fibers. (2001) (148)
- Fluorescence energy transfer in the rapid-diffusion limit. (1978) (140)
- Variability of a bacterial surface protein and disease expression in a possible mouse model of systemic Lyme borreliosis (1994) (137)
- A fluorescence energy transfer method for analyzing protein oligomeric structure: application to phospholamban. (1999) (132)
- Exciton Magnetic Resonance in Wurster's Blue Perchlorate (1963) (131)
- A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction. (1998) (129)
- Rotational dynamics of spin-labeled F-actin in the sub-millisecond time range. (1979) (126)
- Fibronectin mediates Treponema pallidum cytadherence through recognition of fibronectin cell-binding domain (1985) (124)
- Diffusion-enhanced fluorescence energy transfer. (1982) (123)
- Borrelia burgdorferi mutant lacking Osp: biological and immunological characterization (1995) (121)
- Submillisecond rotational dynamics of spin-labeled myosin heads in myofibrils. (1980) (119)
- A flagella-less mutant of Borrelia burgdorferi. Structural, molecular, and in vitro functional characterization. (1991) (115)
- Effect of the lipid environment on protein motion and enzymatic activity of sarcoplasmic reticulum calcium ATPase. (1978) (108)
- Mapping the interaction surface of a membrane protein: unveiling the conformational switch of phospholamban in calcium pump regulation. (2005) (106)
- Interaction of Lyme disease spirochetes with cultured eucaryotic cells (1989) (105)
- Characteristics and Purification of PRR1, an RNA Phage Specific for the Broad Host Range Pseudomonas R1822 Drug Resistance Plasmid (1973) (103)
- Lipid fluidity directly modulates the overall protein rotational mobility of the Ca-ATPase in sarcoplasmic reticulum. (1988) (100)
- Cooperativity in F-actin: binding of gelsolin at the barbed end affects structure and dynamics of the whole filament. (1996) (99)
- An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo (1993) (98)
- Spectroscopic probes of muscle cross-bridge rotation. (1987) (97)
- Motion of subfragment-1 in myosin and its supramolecular complexes: saturation transfer electron paramagnetic resonance. (1975) (96)
- Depolymerization of phospholamban in the presence of calcium pump: a fluorescence energy transfer study. (1999) (94)
- Transverse location of the retinal chromophore of rhodopsin in rod outer segment disc membranes. (1982) (90)
- Pathogen-related oral spirochetes from dental plaque are invasive (1991) (87)
- Effects of membrane thickness on the molecular dynamics and enzymatic activity of reconstituted Ca-ATPase. (1994) (83)
- Methodology for increased precision in saturation transfer electron paramagnetic resonance studies of rotational dynamics. (1986) (82)
- Rotational motion of the sarcoplasmic reticulum Ca2+-ATPase. (1978) (81)
- Specific adherence of Borrelia burgdorferi extracellular vesicles to human endothelial cells in culture (1993) (79)
- The mechanism of force generation in myosin: a disorder-to-order transition, coupled to internal structural changes. (1995) (78)
- Localization of the ganglioside-binding site of fibronectin. (1986) (77)
- In vitro association of leptospires with host cells (1990) (76)
- Rotational dynamics of protein and boundary lipid in sarcoplasmic reticulum membrane. (1982) (75)
- Resolution of three structural states of spin-labeled myosin in contracting muscle. (1995) (73)
- Microsecond rotational motions of eosin-labeled myosin measured by time-resolved anisotropy of absorption and phosphorescence. (1984) (72)
- Characterization of Borrelia burgdorferi invasion of cultured endothelial cells. (1991) (72)
- Effects of AMPPNP on the orientation and rotational dynamics of spin-labeled muscle cross-bridges. (1988) (71)
- Synthetic null-cysteine phospholamban analogue and the corresponding transmembrane domain inhibit the Ca-ATPase. (2000) (70)
- Temperature dependence of rotational dynamics of protein and lipid in sarcoplasmic reticulum membranes. (1986) (70)
- Rotational dynamics of lipid and the Ca-ATPase in sarcoplasmic reticulum. The molecular basis of activation by diethyl ether. (1987) (69)
- Interaction of bee venom melittin with zwitterionic and negatively charged phospholipid bilayers: a spin-label electron spin resonance study. (1997) (68)
- The physical mechanism of calcium pump regulation in the heart. (1994) (68)
- Large-scale rotational motions of proteins detected by electron paramagnetic resonance and fluorescence. (1978) (62)
- Effects of Ser16 phosphorylation on the allosteric transitions of phospholamban/Ca(2+)-ATPase complex. (2006) (58)
- Microsecond rotational dynamics of actin: spectroscopic detection and theoretical simulation. (1996) (57)
- Transients in orientation of a fluorescent cross-bridge probe following photolysis of caged nucleotides in skeletal muscle fibres. (1992) (57)
- Saturation transfer electron paramagnetic resonance on membrane-bound proteins. I-Rotational diffusion of rhodopsin in the visual receptor membrane. (1977) (57)
- Cysteine reactivity and oligomeric structures of phospholamban and its mutants. (1998) (56)
- Site-specific derivatives of wheat germ calmodulin. Interactions with troponin and sarcoplasmic reticulum. (1988) (53)
- Rotational dynamics of the Ca-ATPase in sarcoplasmic reticulum studied by time-resolved phosphorescence anisotropy. (1990) (52)
- Resolution of conformational states of spin-labeled myosin during steady-state ATP hydrolysis. (1987) (50)
- Myosin heads have a broad orientational distribution during isometric muscle contraction: time-resolved EPR studies using caged ATP. (1990) (50)
- Effects of melittin on molecular dynamics and Ca-ATPase activity in sarcoplasmic reticulum membranes: time-resolved optical anisotropy. (1991) (49)
- Cooperativity in F-actin: chemical modifications of actin monomers affect the functional interactions of myosin with unmodified monomers in the same actin filament. (1993) (48)
- The quantitative measurement of rotational motion of the subfragment-1 region of myosin by saturation transfer epr spectroscopy. (1975) (48)
- A Monoclonal Antibody to OspA Inhibits Association of Borrelia burgdorferi with Human Endothelial Cells (1993) (47)
- Rotational dynamics and protein-protein interactions in the Ca-ATPase mechanism. (1988) (47)
- Rotational dynamics of actin-bound myosin heads in active myofibrils. (1993) (46)
- Photolysis of a photolabile precursor of ATP (caged ATP) induces microsecond rotational motions of myosin heads bound to actin. (1989) (46)
- Adherence to and penetration through endothelial cells by oral treponemes. (1999) (45)
- Microsecond rotational motion of spin-labeled myosin heads during isometric muscle contraction. Saturation transfer electron paramagnetic resonance. (1989) (45)
- Microsecond rotational dynamics of phosphorescent-labeled muscle cross-bridges. (1988) (44)
- Conformational transitions in the calcium adenosinetriphosphatase studied by time-resolved fluorescence resonance energy transfer. (1989) (44)
- Fibronectin tetrapeptide is target for syphilis spirochete cytadherence (1985) (44)
- The effect of calcium and prostaglandin inhibitors on the intestinal fluid response to heat-stable enterotoxin of Escherichia coli. (1982) (44)
- Effect of ADP on the orientation of spin-labeled myosin heads in muscle fibers: a high-resolution study with deuterated spin labels. (1990) (44)
- In vitro model of Treponema pallidum invasiveness (1989) (43)
- Perturbations of functional interactions with myosin induce long-range allosteric and cooperative structural changes in actin. (1997) (43)
- Effects of melittin on molecular dynamics and Ca-ATPase activity in sarcoplasmic reticulum membranes: electron paramagnetic resonance. (1991) (42)
- Anesthetics alter the physical and functional properties of the Ca-ATPase in cardiac sarcoplasmic reticulum. (1995) (42)
- Muscle cross-bridges: do they rotate? (1984) (42)
- Mechanochemical coupling in spin-labeled, active, isometric muscle. (1999) (40)
- Time-resolved rotational dynamics of phosphorescent-labeled myosin heads in contracting muscle fibers. (1990) (40)
- Orientational disorder and motion of weakly attached cross-bridges. (1991) (40)
- Orientation of intermediate nucleotide states of indane dione spin-labeled myosin heads in muscle fibers. (1996) (39)
- Putative Treponema pallidum cytadhesins share a common functional domain (1985) (39)
- Molecular mechanism of Ca-ATPase activation by halothane in sarcoplasmic reticulum. (1993) (38)
- Halothane and cyclopiazonic acid modulate Ca-ATPase oligomeric state and function in sarcoplasmic reticulum. (1994) (37)
- Relationship between protein rotational dynamics and phosphoenzyme decomposition in the sarcoplasmic reticulum Ca-ATPase. (1988) (37)
- ATP induces microsecond rotational motions of myosin heads crosslinked to actin. (1986) (37)
- Protein rotational mobility and lipid fluidity of purified and reconstituted cytochrome c oxidase. (1980) (36)
- Rotational dynamics of spin-labeled F-actin during activation of myosin S1 ATPase using caged ATP. (1991) (35)
- Measurement of rotational molecular motion by time-resolved saturation transfer electron paramagnetic resonance. (1986) (35)
- Selective detection of the rotational dynamics of the protein-associated lipid hydrocarbon chains in sarcoplasmic reticulum membranes. (1989) (35)
- Identification of a highly cross-reactive outer surface protein B epitope among diverse geographic isolates of Borrelia spp. causing Lyme disease (1994) (35)
- Microsecond rotational dynamics of spin-labeled myosin regulatory light chain induced by relaxation and contraction of scallop muscle. (1998) (33)
- Site-specific mutations in the myosin binding sites of actin affect structural transitions that control myosin binding. (2001) (32)
- Enhanced levels of attachment of fibronectin-primed Treponema pallidum to extracellular matrix (1986) (32)
- Conformational transitions of the sarcoplasmic reticulum Ca-ATPase studied by time-resolved EPR and quenched-flow kinetics. (1995) (31)
- Rotational dynamics of actin-bound intermediates of the myosin adenosine triphosphatase cycle in myofibrils. (1994) (31)
- Structural, Molecular, and In Vitro Functional Characterization (1991) (31)
- Phosphorylation-induced structural change in phospholamban and its mutants, detected by intrinsic fluorescence. (1998) (31)
- Saturation transfer electron paramagnetic resonance of spin-labeled muscle fibers. Dependence of myosin head rotational motion on sarcomere length. (1984) (30)
- Pulsed-field gel electrophoretic analysis of leptospiral DNA (1991) (30)
- Differential association of Borrelia species with cultured neural cells. (1994) (30)
- Effects of melittin on lipid-protein interactions in sarcoplasmic reticulum membranes. (1992) (29)
- Rotational dynamics of actin-bound intermediates in the myosin ATPase cycle. (1991) (29)
- High-Resolution Detection of muscle Crossbridge Orientation by Electron Paramagnetic Resonance. (1986) (29)
- Transient detection of spin-labeled myosin subfragment 1 conformational states during ATP hydrolysis. (1993) (29)
- Effects of vanadate on the rotational dynamics of spin-labeled calcium adenosinetriphosphatase in sarcoplasmic reticulum membranes. (1986) (27)
- Enhanced EPR sensitivity from a ferroelectric cavity insert. (2001) (27)
- Hexanol and lidocaine affect the oligomeric state of the Ca-ATPase of sarcoplasmic reticulum. (1994) (27)
- Differences in structural dynamics of muscle and yeast actin accompany differences in functional interactions with myosin. (1999) (27)
- Orientational distribution of spin-labeled actin oriented by flow. (1992) (25)
- Zero‐Field Exciton Magnetic Resonance (1964) (25)
- Isolation of oral spirochetes from dogs and cats and provisional identification using polymerase chain reaction (PCR) analysis specific for human plaque Treponema spp. (2000) (24)
- A monoclonal antibody to OspA inhibits association of Borrelia burgdorferi with human endothelial cells (1993) (24)
- Different anesthetic sensitivities of skeletal and cardiac isoforms of the Ca-ATPase. (1999) (24)
- Mechanism of Ca-ATPase inhibition by melittin in skeletal sarcoplasmic reticulum. (1995) (24)
- Myosin light-chain domain rotates upon muscle activation but not ATP hydrolysis. (1999) (22)
- Orientational dynamics of indane dione spin-labeled myosin heads in relaxed and contracting skeletal muscle fibers. (1995) (22)
- Binding of dystrophin's tandem calponin homology domain to F-actin is modulated by actin's structure. (2001) (21)
- Simulation of saturation transfer electron paramagnetic resonance spectra for rotational motion with restricted angular amplitude. (1993) (21)
- Borrelia burgdorferi vesicle production occurs via a mechanism independent of immunoglobulin M involvement (1995) (20)
- Synthesis and properties of a conformationally restricted spin-labeled analog of ATP and its interaction with myosin and skeletal muscle. (1992) (20)
- Self-association accompanies inhibition of Ca-ATPase by thapsigargin. (1995) (19)
- Effect of heat-stable enterotoxin of Escherichia coli on cultured mammalian cells. (1983) (19)
- Protein and lipid rotational dynamics in cardiac and skeletal sarcoplasmic reticulum detected by EPR and phosphorescence anisotropy. (1993) (19)
- Interactions of Treponema pallidum with endothelial cell monolayers (1989) (18)
- Fluorescence energy transfer measurements of distances in rhodopsin and the purple membrane protein. (1982) (18)
- Thermodynamics and kinetics of a molecular motor ensemble. (2000) (17)
- A continuous spectrophotometric assay for simultaneous measurement of calcium uptake and ATP hydrolysis in sarcoplasmic reticulum. (1995) (16)
- A spin label that binds to myosin heads in muscle fibers with its principal axis parallel to the fiber axis. (1994) (16)
- Rotational dynamics of the regulatory light chain in scallop muscle detected by time-resolved phosphorescence anisotropy. (1999) (15)
- Saturation transfer EPR spectroscopy on spin-labeled muscle fibers using a loop-gap resonator. (1983) (15)
- Applications of new saturation transfer electron paramagnetic resonance methodology to the rotational dynamics of the Ca-ATPase in sarcoplasmic reticulum membranes. (1986) (15)
- Identification of Borrelia burgdorferi Surface Components by Triton X‐114 Phase Partitioning (1988) (15)
- Microsecond rotational dynamics of spin-labeled Ca-ATPase during enzymatic cycling initiated by photolysis of caged ATP. (1991) (14)
- Terbium probe of calcium-binding sites on the prothrombin-membrane complex. (1986) (14)
- Stimulation of calcium uptake and cyclic GMP synthesis in rat basophilic leukemia cells by Escherichia coli heat-stable enterotoxin (1983) (13)
- The transverse location of the retinal chromophore in the purple membrane by diffusion-enhanced energy transfer. (1989) (13)
- Aspects of adherence of oral spirochetes. (1996) (13)
- Saturation transfer electron parametric resonance of an indane-dione spin-label. Calibration with hemoglobin and application to myosin rotational dynamics. (1993) (12)
- Resolved conformational states of spin-labeled Ca-ATPase during the enzymatic cycle. (1992) (12)
- Temperature-dependent abnormalities of the erythrocyte membrane in porcine malignant hyperthermia. (1987) (12)
- Molecular dynamics in mouse atrial tumor sarcoplasmic reticulum. (1995) (11)
- Molecular orbital calculations of the catalytic effect of lysozyme. I. Glu 35 as general acid catalyst. (1972) (11)
- Phospholamban-dependent effects of C12E8 on calcium transport and molecular dynamics in cardiac sarcoplasmic reticulum. (1996) (10)
- Protein-lipid interactions within purified and reconstituted cytochrome C reductase and oxidase. (1982) (9)
- An overview of actin structure and actin-binding proteins. (2001) (9)
- Tb3+ binding to bovine prothrombin and bovine prothrombin fragment 1. (1985) (8)
- An autoinhibitory peptide from the erythrocyte Ca-ATPase aggregates and inhibits both muscle Ca-ATPase isoforms. (1999) (8)
- Differential effects of general anesthetics on the quaternary structure of the Ca-ATPases of cardiac and skeletal sarcoplasmic reticulum. (1998) (7)
- An electron paramagnetic resonance study of skeletal muscle membrane fluidity in malignant hyperthermia. (1989) (7)
- Angular disorder of weak-binding actomyosin cross-bridges. (1994) (7)
- Ionic effects on the rotational dynamics of cross-bridges in myosin filaments, measured by triplet absorption anisotropy. (1988) (7)
- Effect of cholera enterotoxin on calcium uptake and cyclic AMP accumulation in rat basophilic leukemia cells. (1984) (5)
- Pollard to actomyosin: "freeze! Don't even move your head". (1993) (5)
- Interaction ofLymeDisease Spirochetes withCultured Eucaryotic Cells (1989) (4)
- Effect of lodoxamide on the secretory response induced by Escherichia coli and Vibrio cholerae enterotoxins in infant mice (1984) (4)
- Heterogeneity of SH groups in sarcoplasmic reticulum. (1977) (3)
- EPR evidence for nucleotide effects on attached cross-bridges. (1988) (3)
- Blitz and blizzard: crossbridges and chaos. (1993) (3)
- Epitopes on surface antigens other than OspA can elicit a bactericidal effect against Lyme disease borrelias. (1995) (2)
- Muscle chemistry and force. (2000) (2)
- Specific Adherence ofBorrelia burgdorferi Extracellular Vesicles toHumanEndothelial Cells inCulture (1993) (2)
- Penetration ofEndothelial CellMonolayers byBorrelia burgdorferi (1989) (2)
- Deficient ER Acetyl-CoA Import in Acinar Cells Leads to Chronic Pancreatitis (2020) (1)
- Rotational dynamics of spin-labelled muscle proteins. (1983) (1)
- Mechanochemical coupling in muscle. (2000) (1)
- Comment on ‘Geometrical constraints affecting crossbridge formation in insect flight muscle’ (1984) (0)
- Pathogen-Related OralSpirochetes fromDental Plaque AreInvasive (1991) (0)
- Terbium bound to the high affinity calcium binding sites of the sarcoplasmic reticulum atpase is less than 10a from the aqueous interface (1986) (0)
- AnOspBMutant ofBorrelia burgdorferi HasReduced Invasiveness InVitro andReduced Infectivity InVivo (1993) (0)
- The magnetic resonance of triplet excitons in solid free radicals. A zero field magnetic resonance spectrometer (1964) (0)
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