Daniel Edward Koshland

Daniel Edward Koshland's AcademicInfluence.com Rankings

Chemistry

#267

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#539

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chemistry Degrees

Daniel Edward Koshland

Biology

#915

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#1601

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Molecular Biology

#54

World Rank

#55

Historical Rank

Biochemistry

#55

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#72

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biology Degrees

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Chemistry
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Daniel Edward Koshland's Degrees

PhD Chemistry University of Chicago

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Daniel Edward Koshland's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Comparison of experimental binding data and theoretical models in proteins containing subunits. (1966) (2566)
Proceedings of the National Academy of Sciences of the United States of America. Annual subject and author indexes. (1990) (2482)
Application of a Theory of Enzyme Specificity to Protein Synthesis. (1958) (1941)
An amplified sensitivity arising from covalent modification in biological systems. (1981) (1204)
The gradient-sensing mechanism in bacterial chemotaxis. (1972) (828)
STEREOCHEMISTRY AND THE MECHANISM OF ENZYMATIC REACTIONS (1953) (820)
A method for the quantitative modification and estimation of carboxylic acid groups in proteins. (1967) (783)
The Key–Lock Theory and the Induced Fit Theory (1995) (546)
The catalytic and regulatory properties of enzymes. (1968) (493)
Amplification and adaptation in regulatory and sensory systems. (1982) (423)
Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump (2003) (392)
Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand. (1995) (365)
Negative cooperativity in enzyme action. The binding of diphosphopyridine nucleotide to glyceraldehyde 3-phosphate dehydrogenase. (1968) (353)
Identification of the site of phosphorylation of the chemotaxis response regulator protein, CheY. (1989) (292)
[56] Carbodiimide modification of proteins. (1972) (283)
Negative cooperativity in regulatory enzymes. (1969) (280)
A piston model for transmembrane signaling of the aspartate receptor. (1999) (271)
Identification of a protein methyltransferase as the cheR gene product in the bacterial sensing system. (1977) (254)
Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate. (1987) (252)
Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. (1986) (247)
Frontiers in neuroscience. (1988) (244)
The Seven Pillars of Life (2002) (227)
Regulation of an enzyme by phosphorylation at the active site. (1991) (226)
Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes. (1991) (219)
Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects. (1984) (217)
Global flexibility in a sensory receptor: a site-directed cross-linking approach. (1987) (205)
A colorimetric procedure for the quantitative determination of tryptophan residues in proteins. (1967) (203)
Structure of a bacterial enzyme regulated by phosphorylation, isocitrate dehydrogenase. (1989) (199)
A protein methylesterase involved in bacterial sensing. (1978) (198)
Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences. (1997) (193)
Half-of-the-sites reactivity and the conformational states of cytidine triphosphate synthetase. (1971) (190)
Site-directed cross-linking. Establishing the dimeric structure of the aspartate receptor of bacterial chemotaxis. (1988) (190)
Biochemistry of sensing and adaptation in a simple bacterial system. (1981) (189)
A response regulator model in a simple sensory system. (1977) (186)
CORRELATION OF STRUCTURE AND FUNCTION IN ENZYME ACTION. (1963) (184)
A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle (1982) (183)
Reaction of tyrosine residues in proteins with carbodiimide reagents. (1968) (182)
Common Mechanism for Repellents and Attractants in Bacterial Chemotaxis (1973) (176)
The Molecule of the Year. (1989) (175)
Membrane receptors for aspartate and serine in bacterial chemotaxis. (1979) (173)
Enzyme flexibility and enzyme action. (1959) (172)
Replacement and amplification of bacterial genes with sequences altered in vitro. (1983) (171)
A method for characterizing the type and numbers of groups involved in enzyme action. (1961) (169)
Determination of flux through the branch point of two metabolic cycles. The tricarboxylic acid cycle and the glyoxylate shunt. (1984) (168)
Molecular evolution of the C-terminal cytoplasmic domain of a superfamily of bacterial receptors involved in taxis. (1996) (166)
Diagnostic uses of the Hill (Logit and Nernst) plots. (1975) (159)
Identification of amino acids involved in phosphoglucomutase action. (1962) (158)
The significance of intermediary plateau regions in enzyme saturation curves. (1969) (156)
Sensitivity amplification in biochemical systems (1982) (152)
The branch point effect. Ultrasensitivity and subsensitivity to metabolic control. (1984) (152)
Quantitative analysis of bacterial migration in chemotaxis. (1972) (152)
The conversion of serine at the active site of subtilisin to cysteine: a "chemical mutation". (1966) (150)
7 The Molecular Basis for Enzyme Regulation (1970) (149)
An Environmentally-Sensitive Reagent with Selectivity for the Tryptophan Residue in Proteins (1964) (148)
Separation of signal transduction and adaptation functions of the aspartate receptor in bacterial sensing. (1983) (148)
Quantitation of the sensory response in bacterial chemotaxis. (1975) (146)
A Procedure for the Selective Modification of Carboxyl Groups in Proteins (1966) (146)
Competitive Inhibition by Substrate during Enzyme Action. Evidence for the Induced-fit Theory1,2 (1960) (145)
Homologies between the Salmonella typhimurium CheY protein and proteins involved in the regulation of chemotaxis, membrane protein synthesis, and sporulation. (1985) (145)
High-resolution structures of the ligand binding domain of the wild-type bacterial aspartate receptor. (1996) (144)
Proteomics and Models for Enzyme Cooperativity* 210 (2002) (143)
A clogged gutter mechanism for protease inhibitors (2002) (139)
Autophosphorylation of protein kinase C at three separated regions of its primary sequence. (1990) (133)
Compensatory phosphorylation of isocitrate dehydrogenase. A mechanism for adaptation to the intracellular environment. (1985) (130)
Domain structure and phosphorylation of protein kinase C. (1987) (130)
Effect of Catalysts on the Hydrolysis of Acetyl Phosphate. Nucleophilic Displacement Mechanisms in Enzymatic Reactions1 (1952) (129)
Kinetic aspects of conformational changes in proteins. I. Rate of regain of enzyme activity from denatured proteins. (1971) (128)
Bacterial motility and chemotaxis: light-induced tumbling response and visualization of individual flagella. (1974) (126)
Aspartate receptors of Escherichia coli and Salmonella typhimurium bind ligand with negative and half-of-the-sites cooperativity. (1994) (125)
Branch point control by the phosphorylation state of isocitrate dehydrogenase. A quantitative examination of fluxes during a regulatory transition. (1985) (122)
A source for the special catalytic power of enzymes: orbital steering. (1970) (120)
Identification of a gamma-glutamyl methyl ester in bacterial membrane protein involved in chemotaxis. (1977) (120)
The Role of Flexibility in Enzyme Action (1963) (119)
The role of negative cooperativity and half-of-the-sites reactivity in enzyme regulation. (1976) (116)
Electrostatic and steric contributions to regulation at the active site of isocitrate dehydrogenase. (1990) (114)
Disulfide cross-linking studies of the transmembrane regions of the aspartate sensory receptor of Escherichia coli. (1991) (113)
Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. (1995) (113)
Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C. (1987) (112)
The structural basis of negative cooperativity: receptors and enzymes. (1996) (111)
Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates. (2006) (110)
Structural biology: A new model for protein stereospecificity (2000) (109)
Propagating conformational changes over long (and short) distances in proteins (2001) (108)
Characterization of rate-controlling steps in vivo by use of an adjustable expression vector. (1985) (107)
Positive and negative cooperativity in yeast glyceraldehyde 3-phosphate dehydrogenase. (1970) (106)
Structure of isocitrate dehydrogenase with isocitrate, nicotinamide adenine dinucleotide phosphate, and calcium at 2.5-A resolution: a pseudo-Michaelis ternary complex. (1993) (105)
Frontiers in immunology. (1987) (105)
Roles of cheY and cheZ gene products in controlling flagellar rotation in bacterial chemotaxis of Escherichia coli (1987) (105)
Structure of a bacterial sensory receptor. A site-directed sulfhydryl study. (1988) (103)
Evidence for protein kinase activities in the prokaryote Salmonella typhimurium. (1978) (102)
Role of an allosteric effector. Guanosine triphosphate activation in cytosine triphosphate synthetase. (1972) (101)
Determination of in Vivo Phosphorylation Sites in Protein Kinase C (*) (1995) (98)
Phosphorylation site of NtrC, a protein phosphatase whose covalent intermediate activates transcription (1992) (98)
Distinct cellular and regional localization of immunoreactive protein kinase C in rat brain. (1987) (97)
Tuning the responsiveness of a sensory receptor via covalent modification. (1991) (95)
Protein Shape and Biological Control (1973) (95)
The application and usefulness of the ratio k(cat)/K(M). (2002) (95)
Induction and expression of long- and short-term neurosecretory potentiation in a neural cell line (1990) (95)
Cytidine triphosphate synthetase. Covalent intermediates and mechanisms of action. (1971) (94)
Sensory electrophysiology of bacteria: relationship of the membrane potential to motility and chemotaxis in Bacillus subtilis. (1977) (93)
Identification of the ribose binding protein as the receptor for ribose chemotaxis in Salmonella typhimurium. (1974) (93)
The Era of Pathway Quantification (1998) (93)
Conformational changes: How small is big enough? (1998) (92)
Electron acceptor taxis and blue light effect on bacterial chemotaxis (1979) (92)
A Small-Molecule Modulator of Poly-α2,8-Sialic Acid Expression on Cultured Neurons and Tumor Cells (2001) (91)
The three-dimensional structure of the ligand-binding domain of a wild-type bacterial chemotaxis receptor. Structural comparison to the cross-linked mutant forms and conformational changes upon ligand binding. (1994) (90)
High cooperativity, specificity, and multiplicity in the protein kinase C-lipid interaction. (1989) (90)
Associations and Democracy (1985) (90)
Receptor structure in the bacterial sensing system. (1980) (89)
Isolation, characterization and complementation of Salmonella typhimurium chemotaxis mutants. (1975) (88)
Half-of-the sites reactivity and negative co-operativity: the case of yeast glyceraldehyde 3-phosphate dehydrogenase. (1973) (86)
Ligand-induced dimer-to-tetramer transformation in cytosine triphosphate synthetase. (1972) (85)
Kineticsspects of conformational changes in proteins. II. Structural changes in renaturation of denatured proteins. (1971) (85)
Cell cycle-dependent methyl esterification of lamin B. (1987) (85)
The formation of anhydrochymotrypsin by removing the elements of water from the serine at the active site. (1966) (85)
Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme. (1991) (85)
The molecule of the year. (1990) (83)
Sites of methyl esterification and deamination on the aspartate receptor involved in chemotaxis. (1984) (81)
Reversal of Flagellar Rotation in Monotrichous and Peritrichous Bacteria: Generation of Changes in Direction (1974) (79)
Indication of the magnitude of orientation factors in esterification (1972) (77)
Intrinsic and extrinsic light responses of Salmonella typhimurium and Escherichia coli (1975) (77)
Inversion of a behavioral response in bacterial chemotaxis: explanation at the molecular level. (1978) (76)
The role of a signaling protein in bacterial sensing: behavioral effects of increased gene expression. (1984) (76)
Crystallization and preliminary X-ray diffraction study of the ligand-binding domain of the bacterial chemotaxis-mediating aspartate receptor of Salmonella typhimurium. (1991) (76)
Models for cooperative effects in proteins containing subunits. Effects of two interacting ligands. (1967) (76)
The subunit structure and subunit interactions of cytidine triphosphate synthetase. (1970) (75)
Kinetic mechanism of Escherichia coli isocitrate dehydrogenase. (1993) (75)
The molecule of the year. (1990) (75)
Functional homology of chemotaxis genes in Escherichia coli and Salmonella typhimurium (1979) (73)
Multiple methylation in processing of sensory signals during bacterial chemotaxis. (1980) (73)
Multiple kinetic states for the flagellar motor switch (1989) (73)
The comparison of non-enzymic and enzymic reaction velocities (1962) (72)
Kinetics of receptor modification. The multiply methylated aspartate receptors involved in bacterial chemotaxis. (1986) (72)
EVIDENCE FOR CONFORMATION CHANGES INDUCED BY SUBSTRATES OF PHOSPHOGLUCOMUTASE. (1965) (70)
Evidence for an S-adenosylmethionine requirement in the chemotactic behavior of Salmonella typhimurium. (1975) (70)
A ribose binding protein of Salmonella typhimurium. (1972) (70)
Sensitivity of metabolic fluxes to covalent control. (1985) (70)
Additive and independent responses in a single receptor: Aspartate and maltose stimuli on the tar protein (1987) (69)
Switches, thresholds and ultrasensitivity (1987) (68)
The reaction of hydroxamic acids with water-soluble carbodiimides. A Lossen rearrangement. (1968) (68)
Intrasubunit signal transduction by the aspartate chemoreceptor. (1991) (66)
The active site and enzyme action. (2006) (66)
Phosphorylation inactivates Escherichia coli isocitrate dehydrogenase by preventing isocitrate binding. (1989) (65)
A model regulatory system: bacterial chemotaxis. (1979) (64)
Prediction of the structure of a receptor–protein complex using a binary docking method (1992) (64)
Effect of temperature on the rate of hydrolysis of adenosine triphosphate and inosine triphosphate by myosin with and without modifiers. Evidence for a change in protein conformation. (1962) (64)
Refined structures of the ligand-binding domain of the aspartate receptor from Salmonella typhimurium. (1993) (64)
Economic impact report. (1992) (64)
Protein kinase C autophosphorylates by an intrapeptide reaction. (1987) (63)
Chemotaxis as a model second-messenger system. (1988) (63)
Carboxyl group modification in chymotrypsin and chymotrypsinogen. (1969) (63)
Role of Methionine in Bacterial Chemotaxis (1974) (63)
Bacterial chemotaxis in relation to neurobiology. (1980) (62)
Methylation of the Escherichia coli chemotaxis receptors: intra- and interdimer mechanisms. (1997) (62)
Use of a distant reporter group as evidence for a conformational change in a sensory receptor. (1977) (62)
ROLE OF SERINE IN CHYMOTRYPSIN ACTION. CONVERSION OF THE ACTIVE SERINE TO DEHYDROALANINE. (1963) (61)
Purification and characterization of the periplasmic domain of the aspartate chemoreceptor. (1993) (61)
Neither methylating nor demethylating enzymes are required for bacterial chemotaxis (1985) (61)
Properties of the galactose binding protein of Salmonella typhimurium and Escherichia coli. (1977) (60)
Receptor interactions in a signalling system: competition between ribose receptor and galactose receptor in the chemotaxis response. (1976) (60)
Carboxyl group modification and the activity of lysozyme. (1969) (60)
Properties of thiol-subtilisin. The consequences of converting the active serine residue to cysteine in a serine protease. (1968) (59)
MECHANISM of action of alkaline phosphatase. (1952) (58)
Correlation of bond breaking with enzyme specificity; cleavage point of invertase. (1954) (58)
The role of calcium in fusion of artificial vesicles. (1978) (57)
To see ourselves as others see us. (1990) (57)
Molecule of the year. (1993) (57)
Role of the CheW protein in bacterial chemotaxis: overexpression is equivalent to absence (1989) (56)
Attractant- and disulfide-induced conformational changes in the ligand binding domain of the chemotaxis aspartate receptor: a 19F NMR study. (1994) (55)
Phosphatidylserine affects specificity of protein kinase C substrate phosphorylation and autophosphorylation. (1990) (55)
The identification of distinct protein kinases and phosphatases in the prokaryote Salmonella typhimurium. (1981) (55)
Effect of small changes in orientation on reaction rate (1972) (55)
Theoretical aspects of orbital steering. (1971) (54)
Mechanism of hydrolysis of adenosinetriphosphate by muscle proteins and its relation to muscular contraction. (1959) (54)
Fraud in science. (1987) (54)
Millisecond Laue structures of an enzyme–product complex using photocaged substrate analogs (1998) (54)
Induction and expression of long- and short-term neurosecretory potentiation in a neural cell line (1995) (53)
USE OF "REPORTER GROUPS" IN STRUCTURE-FUNCTION STUDIES OF PROTEINS. (1964) (53)
Changing reactivity of receptor carboxyl groups during bacterial sensing. (1981) (52)
Potentiation, desensitization, and inversion of response in bacterial sensing of chemical stimuli. (1978) (51)
The addictive personality. (1990) (51)
A diffusion assay for detection and quantitation of methyl-esterified proteins on polyacrylamide gels. (1984) (51)
Energy expenditure in the control of biochemical systems by covalent modification. (1987) (49)
Binding, proteolytic, and crystallographic analyses of mutations at the protease-inhibitor interface of the subtilisin BPN'/chymotrypsin inhibitor 2 complex. (2004) (49)
Receptors and transmembrane signaling. (1992) (48)
Chemotactic mechanism of Salmonella typhimurium: preliminary mapping and characterization of mutants (1977) (48)
A general method for the quantitative determination of saturation curves for multisubunit proteins. (1970) (48)
Differential Effects of Unnatural Sialic Acids on the Polysialylation of the Neural Cell Adhesion Molecule and Neuronal Behavior* (2002) (48)
Transmembrane signaling by a chimera of the Escherichia coli aspartate receptor and the human insulin receptor. (1989) (47)
The quaternary structure of proteins composed of identical subunits. (1971) (47)
Excitatory amino acid uptake and N-methyl-D-aspartate-mediated secretion in a neural cell line. (1990) (47)
Mutational analysis of the catalytic residues lysine 230 and tyrosine 160 in the NADP(+)-dependent isocitrate dehydrogenase from Escherichia coli. (1995) (46)
Purification and characterization of the aspartate chemoreceptor. (1985) (46)
The chemistry of a reporter group: 2-hydroxy-5-nitrobenzyl bromide. (1970) (45)
Molecular cloning of chemotaxis genes and overproduction of gene products in the bacterial sensing system (1981) (45)
Reversible receptor methylation is essential for normal chemotaxis of Escherichia coli in gradients of aspartic acid. (1988) (45)
Fetal tissue research. (1992) (45)
Protein structure and enzyme action. (1958) (45)
Exposure of HeLa DNA polymerase alpha to protein kinase C affects its catalytic properties. (1987) (45)
Cytidine triphosphate synthetase. (1978) (45)
The Cha-Cha-Cha Theory of Scientific Discovery (2007) (44)
Mutations in the aspartate receptor of Escherichia coli which affect aspartate binding. (1990) (43)
PURIFIED MUSCLE PROTEINS AND THE WALKING RATE OF ANTS. (1959) (43)
Sequences and consequences of the human genome. (1989) (42)
Receptor interactions through phosphorylation and methylation pathways in bacterial chemotaxis. (1988) (42)
The hydrolytic activity of glyceraldehyde-3-phosphate dehydrogenase. (1958) (42)
Direct measurement of small ligand-induced conformational changes in the aspartate chemoreceptor using EPR. (1998) (42)
Peer review of peer review. (1985) (41)
Sequence of the flaA (cheC) locus of Escherichia coli and discovery of a new gene (1986) (41)
Bacterial chemotaxis in the absence of receptor carboxylmethylation (1981) (41)
Proteolytic fragments identified with domains of the aspartate chemoreceptor. (1985) (41)
Sites of methyl esterification on the aspartate receptor involved in bacterial chemotaxis. (1983) (40)
Molecule of the year: the DNA repair enzyme. (1994) (40)
The influence of binding domains on the nature of subunit interactions in oligomeric proteins. Application to unusual kinetic and binding patterns. (1970) (40)
Biosynthetic incorporation of unnatural sialic acids into polysialic acid on neural cells. (2000) (39)
A change in specificity of chymotrypsin caused by chemical modification of methionine residues. (1966) (38)
Stereochemistry of enzyme, substrate, and products during beta-amylase action. (1960) (38)
Methyl-esterified proteins in a mammalian cell line. (1985) (38)
[39] Modification of proteins with active benzyl halides. (1972) (38)
Structure of isocitrate dehydrogenase with alpha-ketoglutarate at 2.7-A resolution: conformational changes induced by decarboxylation of isocitrate. (1993) (37)
The environment of a reporter group at the active site of chymotrypsin. (1967) (37)
Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2. (2005) (36)
Transfer of oxygen in the glutamine synthetase reaction. (1956) (36)
Mutagenic studies of the interaction between the aspartate receptor and methyltransferase from Escherichia coli. (1994) (35)
Specificity in the assembly of multisubunit proteins. (1969) (35)
Conformational Aspects of Enzyme Regulation (1969) (35)
ENZYME CATALYSIS AND ENZYME SPECIFICITY-COMBINATION OF AMINO ACIDS AT THE ACTIVE SITE OF PHOSPHOGLUCOMUTASE1 (1957) (35)
Half-of-the sites reactivity in the catalytic mechanism of yeast glyceraldehyde 3-phosphate dehydrogenase. (1973) (35)
Caged NADP and NAD. Synthesis and characterization of functionally distinct caged compounds. (1997) (35)
A mechanism for the effects of dinitrophenol and temperature on the hydrolytic activity of myosin. (1959) (35)
Properties of the O18 exchange reaction catalyzed by heavy meromyosin. (1963) (34)
Producing positive, negative, and no cooperativity by mutations at a single residue located at the subunit interface in the aspartate receptor of Salmonella typhimurium. (1996) (34)
Access to phosphorylation in isocitrate dehydrogenase may occur by domain shifting. (1997) (33)
Molecular recognition analyzed by docking simulations: the aspartate receptor and isocitrate dehydrogenase from Escherichia coli. (1993) (33)
Mechanism of Alcoholic Fermentation. The Fermentation of Glucose-1-C¹⁴ (1950) (33)
Membrane fluidity and chemotaxis: effects of temperature and membrane lipid composition on the swimming behavior of Salmonella typhimurium and Escherichia coli. (1977) (33)
Tandem duplication and multiple functions of a receptor gene in bacterial chemotaxis. (1982) (33)
The protein carboxylmethyltransferase involved in Escherichia coli and Salmonella typhimurium chemotaxis. (1984) (32)
Mechanism of hydrolysis of adenosinetriphosphate catalyzed by lobster muscle. (1953) (32)
Habituation in the single cell: diminished secretion of norepinephrine with repetitive depolarization of PC12 cells. (1990) (32)
A rapid purification procedure for glyceraldehyde 3-phosphate dehydrogenase from Bakers' yeast. (1972) (32)
Flagellar formation in Escherichia coli electron transport mutants (1977) (32)
Special essay. The seven pillars of life. (2002) (32)
Simple molecular model for sensing and adaptation based on receptor modification with application to bacterial chemotaxis. (1982) (31)
A CHROMATOGRAPHIC STUDY OF PHOSPHOGLUCOMUTASE: SEPARATION OF PHOSPHO- AND DEPHOSPHO-ENZYME FORMS. (1964) (31)
Active site water molecules revealed in the 2.1 A resolution structure of a site-directed mutant of isocitrate dehydrogenase. (2000) (31)
Control of enzyme activity and metabolic pathways (1984) (30)
The number of binding sites of sweet potato beta amylase. (1963) (30)
Proximity, entropy and orbital steering. (1973) (30)
Role of membrane potential and calcium in chemotactic sensing by bacteria. (1981) (30)
Crystallographic study of the interaction of urea with lysozyme (1974) (30)
Computational method for relative binding energies of enzyme‐substrate complexes (1996) (30)
Surface structure recognized for covalent modification of the aspartate receptor in chemotaxis. (1986) (30)
Solubilization of a vectorial transmembrane receptor in functional form: aspartate receptor of chemotaxis. (1985) (30)
The microbial wars. (1992) (29)
EVIDENCE FOR INVOLVEMENT OF A METHIONINE RESIDUE IN THE ENZYMATIC ACTION OF PHOSPHOGLUCOMUTASE AND CHYMOTRYPSIN (1960) (29)
Characterization of slowly interconvertible states of phosphoribosyladenosine triphosphate synthetase dependent on temperature, substrates, and histidine. (1974) (29)
A rapid isolation of phosphoribosyladenosine triphosphate synthetase and comparison to native enzyme. (1974) (29)
Inactivation of the opiate receptor in bovine caudate nucleus by azide enkephalin analogs. (1980) (29)
Molecular cloning and amplification of the adenylate cyclase gene. (1981) (29)
Covalent Enzyme-Substrate Intermediates (1971) (29)
Structural basis for a change in substrate specificity: crystal structure of S113E isocitrate dehydrogenase in a complex with isopropylmalate, Mg2+, and NADP. (2001) (28)
Preserving biodiversity. (1991) (28)
Conditional activation of cAMP signal transduction by protein kinase C. The effect of phorbol esters on adenylyl cyclase in permeabilized and intact cells. (1994) (28)
Molecular geometry in enzyme action. (1956) (28)
[65] Reactions with reactive alkyl halides (1967) (28)
In vitro methylation of bacterial chemotaxis proteins: characterization of protein methyltransferase activity in crude extracts of Salmonella typhimurium. (1980) (28)
Chemotaxis as a model for sensory systems (1974) (27)
[88] Environmentally sensitive groups attached to proteins (1972) (27)
Subunit interactions in yeast glyceraldehyde-3-phosphate dehydrogenase. (1975) (27)
Protonmotive force and bacterial sensing (1980) (27)
Redesigning the substrate specificity of an enzyme: isocitrate dehydrogenase. (2000) (26)
Three amino acids at the active site of beta amylase (1960) (26)
The role of the protein core in the inhibitory power of the classic serine protease inhibitor, chymotrypsin inhibitor 2. (2003) (26)
The amino terminus of the aspartate chemoreceptor is formylmethionine. (1990) (26)
Contributions made by individual methylation sites of the Escherichia coli aspartate receptor to chemotactic behavior. (1995) (26)
Permeabilization of cells for studies on the biochemistry of bacterial chemotaxis. (1979) (26)
Kinetics of Peptide Bond Formation1 (1951) (25)
The price of progress. (1988) (25)
Reactive lysines of yeast glyceraldehyde 3-phosphate dehydrogenase. Attachment of a reporter group to a specific non-essential residue. (1973) (25)
SHINKE R, RUSCICA J: INFLUENCE OF SULFHYDRYL GROUPS ON THE ACTIVITY OF SWEET POTATO BETA-AMYLASE. (1965) (25)
Diagnostic relationships in the relaxation spectrometry of allosteric enzymes. (1972) (25)
Properties of the phosphorylated active site of phosphoglucomutase. (1957) (25)
16. CTP Synthetase and Related Enzymes (1974) (25)
Evolution of catalytic function. (1987) (24)
Structure and dynamics of transmembrane signaling by the Escherichia coli aspartate receptor. (1992) (24)
The two-component pathway comes to eukaryotes. (1993) (24)
TheGradient-Sensing Mechanism inBacterial Chemotaxis (1972) (24)
Identification of a bacterial sensing protein and effects of its elevated expression (1985) (24)
Conflict of interest policy. (1992) (24)
Careers in science (1991) (24)
Half-of-the-sites reactivity of yeast glyceraldehyde 3-phosphate dehydrognease. (1972) (23)
Effect of an induced conformational change on the physical properties of two chemotactic receptor molecules. (1979) (23)
MOLECULAR WEIGHT OF THE PHOSPHO AND DEPHOSPHO FORMS OF PHOSPHOGLUCOMUTASE. (1963) (23)
Multiple aggregation states of phosphoribosyladenosine triphosphate synthetase. (1974) (22)
Three‐dimensional structural model of the serine receptor ligand‐binding domain (1993) (22)
The rational approach to the irrational. (1990) (22)
The reversible phosphorylation of isocitrate dehydrogenase of Salmonella typhimurium. (1982) (22)
Biochemistry of sensing and adaptation (1980) (21)
Properties of the active site in myosin hydrolysis of adenosine triphosphate as indicated by the O18-exchange reaction. (1960) (21)
Acid and base catalysis in a non-enzymic transfer reaction; a possible enzyme model. (1957) (21)
The importance of orientation factors in enzymatic reactions. (1972) (21)
Isotopic exchange criteria for enzyme mechanisms (1955) (21)
Chemotaxis in Escherichia coli proceeds efficiently from different initial tumble frequencies (1990) (21)
Calcium- and lipid-independent protein kinase C autophosphorylation. Activation by low pH. (1989) (20)
ENVIRONMENTALLY SENSITIVE PROTEIN REAGENTS. 2-METHOXY-5-NITROBENZYL BROMIDE. (1965) (20)
Parallel pathways for habituation in repetitively stimulated PC12 cells (1990) (20)
The mechanism of the galactose-glucose interconversion in Lactobacillus bulgaricus. (1956) (20)
A general procedure for screening inhibitory antibodies: application for identifying anti-protein kinase C antibodies. (1988) (20)
Allosteric properties of the first enzyme of the histidine operon (1971) (20)
Conformational changes in the cytoplasmic domain of the Escherichia coli aspartate receptor upon adaptive methylation. (1998) (19)
The effect of NAD+ on the catalytic efficiency of glyceraldehyde-3-phosphate dehydrogenase from rabbit muscle. (1970) (19)
Determinants of performance in the isocitrate dehydrogenase of Escherichia coli (1996) (19)
Soluble and membrane-bound aspartate-binding activities in Salmonella typhimurium (1975) (18)
Mg2+, Ca2+-dependent adenosine triphosphatase as receptor for divalent cations in bacterial sensing. (1976) (18)
The bacterium as a model neuron (1983) (18)
Modeling substrate binding in Thermus thermophilus isopropylmalate dehydrogenase (1995) (18)
Linking functional domains of the human insulin receptor with the bacterial aspartate receptor. (1986) (18)
The sensitivity of intramolecular reactions to the orientation of the reacting atoms (1971) (17)
Construction and behavior of strains with mutations in two chemotaxis genes (1982) (17)
EVIDENCE FOR AN INTERMEDIATE IN THE HYDROLYSIS OF ATP BY MUSCLE PROTEINS (1958) (17)
A second type of protein methylation reaction in bacterial chemotaxis. (1987) (17)
Synthesis, kinetics, and structural studies of a photolabile caged isocitrate: a catalytic trigger for isocitrate dehydrogenase. (1996) (17)
A GENERAL METHOD FOR THE LABELING OF THE ACTIVE SITE OF ANTIBODIES AND ENZYMES. (1959) (17)
Mechanism of hydrolysis of adenosinetriphosphate catalyzed by purified muscle proteins. (1954) (17)
A HIGHLY REACTIVE COLORED REAGENT WITH SELECTIVITY FOR THE TRYPTOPHAN RESIDUE IN PROTEINS. 2-HYDROXY-5-NITROBENZYL BROMIDE. (1965) (17)
Molecular cloning of a member of a new class of low-molecular-weight GTP-binding proteins. (1991) (17)
Recognizing self from nonself. (1990) (17)
Elephants, monstrosities, and the law. (1992) (17)
The role of water in enzymatic hydrolysis; general method and its application to myosin. (1957) (17)
The chemistry of the modification of tryptophan with 2-hydroxy-5-nitrobenzyl bromide. (1969) (17)
The properties of rabbit muscle glyceraldehyde 3-phosphate dehydrogenase labeled with a "reporter group". (1970) (16)
Persistence as a concept in the motility of chemotactic bacteria. (1973) (16)
[30] Carboxymethyl esterase of bacterial chemotaxis (1984) (16)
The role of methylation in chemotaxis. An explanation of outstanding anomalies. (1990) (16)
Identification of cyclic AMP as the response regulator for neurosecretory potentiation: a memory model system. (1991) (16)
Science advice to the president. (1988) (15)
A single hydrophobic to hydrophobic substitution in the transmembrane domain impairs aspartate receptor function. (1994) (15)
Response to a metal ion-citrate complex in bacterial sensing (1979) (15)
The crystal structures of 1,3,5‐trimethylbenzenetricarbonylmolybdenum and hexamethylbenzenetricarbonylmolybdenum (1977) (15)
The case for diversity. (1994) (15)
The new puritanism. (1990) (15)
Crazy, but correct (2004) (15)
Regulation of neurosecretory habituation in PC12 cells: parallel pathways used by cAMP and calcium. (1992) (15)
Scare of the week. (1989) (15)
The cell cycle. (1989) (15)
Ligand-induced association-dissociation as a means for enzyme purification. (1970) (14)
Sensory Response in Bacteria (1977) (14)
ADENOSINE TRIPHOSPHATE CLEAVAGE DURING THE G-ACTIN TO F-ACTIN TRANSFORMATION AND THE BINDING OF ADENOSINE DIPHOSPHATE TO F-ACTIN. (1964) (14)
An instrument for recording the motions of microorganisms in chemical gradients. (1974) (13)
The introduction of a "reporter" group at the active site of glyceraldehyde-3-phosphate dehydrogenase. (1966) (13)
A tale of two techniques. (1988) (13)
Protein Structure in Relation to Cell Dynamics and Differentiation (1966) (13)
Converting a transmembrane receptor to a soluble receptor: recognition domain to effector domain signaling after excision of the transmembrane domain. (1997) (13)
Flying into the future. (1991) (13)
Retention of habituation in PC12 cells. (1992) (13)
Conformational studies on the interaction of chymotrypsin with substrates and inhibitors. (1965) (13)
Role of tyrosine residues in chymotrypsin action (1964) (12)
Absence of Phosphotriester Linkages in Tobacco Mosaic Virus (1958) (12)
Identification of the tip-encoded receptor in bacterial sensing (1986) (12)
An All-or-None Assay for Assessing the Role of Amino Acid Residues in Enzyme Action--Application to Phosphoglucomutase (1963) (12)
Nature, nurture, and behavior. (1987) (12)
Teaching and research. (1991) (12)
Science in Europe (1987) (11)
How to get paid for having fun. (1996) (11)
Immortality and risk assessment. (1987) (11)
The biological warfare of the future. (1994) (11)
A phosphoribosyl-enzyme covalent intermediate in the first enzyme of histidine biosynthesis. (1970) (11)
The N-terminal Cytoplasmic Tail of the Aspartate Receptor Is Not Essential in Signal Transduction of Bacterial Chemotaxis (*) (1995) (11)
Vibrio cholerae hlyB is a member of the chemotaxis receptor gene family (1993) (11)
The probing of active sites by similar report groups. The preparation of 4-bromoacetamido-2-nitrophenol. (1967) (11)
Control of the receptor for galactose taxis in Salmonella typhimurium (1979) (11)
The cystic fibrosis gene story. (1989) (11)
Bacterial chemotaxis as a simple model for a sensory system (1976) (11)
Minorities in science. (1992) (10)
Compensatory regulation in metabolic pathways--responses to increases and decreases in citrate synthase levels. (1987) (10)
The process of publication. (1989) (10)
Environmentally sensitive groups attached to proteins. (1972) (10)
Science in Asia. (1993) (10)
PROPERTIES OF THE ACTIVE SITE OF ENZYMES * (1963) (10)
Specificity and catalytic power in enzyme action. (1962) (10)
On the mechanism of action of methyl chymotrypsin (1978) (10)
COMPARATIVE BINDING PROPERTIES OF NATIVE AND ANHYDRO CHYMOTRYPSIN DETERMINED BY A COMPETITIVE DIALYSIS METHOD. (1965) (9)
Roles of methylation and phosphorylation in the bacterial sensing system. (1988) (9)
A simple proposal for health care rationing. (1994) (9)
Mechanism of action of 5'-nucleotidase. (1956) (9)
Zero-order Ultrasensitivity in Interconvertible Enzyme Systems (1990) (9)
Molecular basis of enzyme catalysis and control (1971) (9)
Cleavage point during hydrolyses catalyzed by ribonuclease and phosphodiesterase. (1961) (9)
CONFORMATION CHANGES AT THE ACTIVE SITE DURING ENZYME ACTION. (1964) (9)
The Chemotactic Response in Bacteria (1974) (9)
The biochemistry of the neuron. Neurosecretory habituation to repetitive depolarizations in PC12 cells. (1991) (9)
Case of the hidden assumptions (2002) (9)
Simplicity and complexity in conflict of interest. (1993) (9)
Drunk driving and statistical morality. (1989) (9)
The evolution of function in enzymes. (1976) (9)
Science in Russia (1994) (8)
Addendum: A new model for protein stereospecificity (2000) (8)
Arms and the men. (1987) (8)
Credibility in science and the press. (1991) (8)
Two plus two equals five. (1990) (8)
Fermentation of glucose-1-C14. (1949) (8)
Dealing in hot property. (1986) (8)
Women in science. (1988) (7)
Mechanism of hydrolysis of acetylcholine catalyzed by acetylcholinesterase and by hydroxide ion. (1953) (7)
The Role of Methylation in Chemotaxis (1990) (7)
184 Biological specificity in protein small molecule interactions (1961) (7)
A systematic method for introducing heavy atoms into a protein molecule. (1967) (7)
Information processing in a sensory system. (1983) (7)
Frontiers in Biotechnology (1991) (7)
S-methyl glutathione synthesis is catalyzed by the cheR methyltransferase in Escherichia coli (1986) (7)
Animal rights and animal wrongs. (1989) (6)
The computer issue. (1985) (6)
ROLE OF HISTIDINE IN PHOSPHOGLUCOMUTASE. THE USE OF “RATE” AND “ALL-OR-NONE” ASSAYS (1960) (6)
Fetal tissue in research. (1988) (6)
A cyclic mechanism for excitation and adaptation. (1981) (6)
The funding crisis. (1990) (6)
Amino acids involved in the action of chymotrypsin. (1962) (6)
The underside of overhead. (1990) (6)
Scientific literacy. (1985) (6)
Basic research (I) (1993) (6)
The Dirty Air Act. (1990) (6)
The handling of leaked information. (1991) (5)
The Escherichia coli aspartate receptor: sequence specificity of a transmembrane helix studied by hydrophobic-biased random mutagenesis. (1999) (5)
The crystal ball and the trumpet call (1995) (5)
An Editor's Quest (I). (1985) (5)
Women in science (1993) (5)
Scientific competency through fun. (1989) (5)
Modest proposals for the granting system. (1985) (5)
Neurosecretory habituation in PC12 cells: modulation during parallel habituation. (1995) (5)
A new look. (1986) (5)
METHYLATION AND DEMETHYLATION IN THE BACTERIAL CHEMOTACTIC SYSTEM (1979) (5)
Editorial: Women in Science (1993) (5)
Setting priorities in science. (1988) (5)
The dimensions of the brain. (1992) (5)
Solvent effects in the cyclization of thiol amides and hydroxy acids (1977) (5)
Blank check laws. (1989) (5)
Ahead of schedule and on budget. (1994) (5)
The insubordinate computer. (1986) (5)
A tax on sin: the six-cylinder car. (1989) (5)
SECTION OF PHYSICS AND CHEMISTRY: A PHYSICAL ORGANIC APPROACH TO ENZYMATIC MECHANISMS* (1954) (5)
Science and Peace (1991) (5)
Perturbation of the chemotactic tumbling of bacteria. (1976) (4)
Solar power and priorities. (1989) (4)
Scientific evidence in court. (1994) (4)
The Importance of Intelligence (1995) (4)
The confusion profusion. (1989) (4)
Low probability-high consequence accidents. (1989) (4)
The spousal abuse problem. (1994) (4)
Cancer research: prevention and therapy. (1991) (4)
Judicial impact statements. (1988) (4)
Balance in science. (1988) (4)
Science, journalism, and whistle-blowing. (1988) (4)
Response: Preventing Fraud (1989) (4)
The underrepresentation syndrome. (1989) (4)
Further evidence for oxygen exchange at an intermediate stage in myosin hydrolysis. (1962) (4)
Clean thoughts on clean air. (1993) (4)
Health care: more access and more cures. (1993) (4)
Let us meander. (1986) (4)
The joys and vicissitudes of protein science (1993) (4)
Science and society. (1993) (4)
The phosphoglucomutase reaction: investigation of enzyme dephosphorylation during its reaction with substrate. (1967) (4)
The specificity of induced conformational changes. The case of yeast glyceraldehyde-3-phosphate dehydrogenase. (1975) (4)
Protein and biological control. (1973) (4)
Making wolves lovable. (1993) (3)
COMPOSITION AND THERMAL DECOMPOSITION OF URANYL PEROXIDE (1945) (3)
The Contribution of Orientation to the Catalytic Power of Enzymes (1973) (3)
Benefits, risks, vaccines, and the courts. (1985) (3)
The golden median. (1988) (3)
Interview with a risk expert. (1989) (3)
Department of Science. (1985) (3)
Identification of the esterase peptide and its interaction with the cheZ peptide in bacterial sensing. (1981) (3)
A milk-free zone. (1994) (3)
DNA fingerprinting and eyewitness testimony. (1992) (3)
Specific inactivator of flagellar reversal in Salmonella typhimurium (1979) (3)
Economic arteriosclerosis and competitiveness. (1988) (3)
Ballooning around venus. (1986) (3)
An Editor's Quest (II). (1985) (3)
Sensory Adaptation Mechanisms in Swarm Development (1984) (3)
Molecule of the year. (1991) (3)
Dr. Noitall Returns: Just in Time for the Election! (2000) (3)
Achievable New Year's Resolutions. (1992) (3)
Comparative structural studies of phosphoglucomutase and chymotrypsin. (1960) (3)
The engineering of species. (1989) (3)
Health, wealth, and unhappiness. (1985) (3)
Strategic goals on an NIH model. (1994) (3)
Response: Human Genome Program (1989) (3)
To lift the lamp beside the research door. (1986) (3)
Addons and catchons. (1985) (3)
The attractiveness of gloom. (1992) (3)
Epidemics and civil rights. (1987) (3)
Excursions in biotechnology. (1985) (2)
Pygmalion: a play in five acts, (2011) (2)
Research policy and the peace dividend. (1990) (2)
Biotechnology : the renewable frontier (1986) (2)
The epidemiology issue. (1986) (2)
The race for the "gold" in research. (1992) (2)
Identification ofa Bacterial Sensing Protein andEffects ofIts Elevated Expression (1985) (2)
Priority one: rescue the environment. (1990) (2)
The effect of protein modification reagents on the chemotactic response in Salmonella typhimurium. (1979) (2)
Sequencing the human genome. (1987) (2)
The war? Program? Experiment? On drugs. (1989) (2)
Spanking, reason, and the environment. (1986) (2)
Methylation of receptors in chemotaxis of bacteria (1982) (2)
The biotechnology issue. (1986) (2)
Science in Latin America (1995) (2)
Stress for success. (1991) (2)
An overview of overhead. (1991) (2)
The great overcoat scare. (1993) (2)
Society, cure thyself. (1990) (2)
A new approach to faculty salaries. (1989) (2)
Effect of catabolite repression on chemotaxis in Salmonella typhimurium. (1980) (2)
The time traveler. (1994) (2)
In pursuit of the renewable frontier. (1985) (2)
The DNA dragon 1. (1987) (2)
[87] Preparation and properties of acetyl phosphatase (1955) (2)
The biochemistry of the neuron: methods and calculations for the analysis of neurotransmitter secretion from populations of single cells. (1992) (2)
The choosing of the NIH director. (1989) (2)
To retire or not to retire, that is the question. (1988) (2)
Key-Lock Theory and the Induced Fit Theory Introduction of the Induced Fit Theory (1998) (2)
Regulatory control through conformation changes in proteins. (1968) (2)
To: universal science foundation planet utopia galaxy 7,073,216. (1985) (2)
Earthquakes and collective action. (1994) (2)
Research in the service of jobs and health. (1994) (2)
The omnipotence scandal. (1987) (2)
SOS, Save Our Science. (1990) (2)
The Amino Terminus of the Aspartate Chemoreceptor (2001) (2)
Basic research (III): Priorities. (1993) (2)
Sources for new scientists. (1986) (2)
Toxic chemicals and toxic laws (1991) (2)
Regulation of neurosecretory habituation by cAMP. Role of adaptation of cAMP signals. (1993) (2)
Rate accelerations by alteration in the orientation of reacting atoms. Comparison of lactonizations in bicyclo[2,2,2] and bicyclo[2,2,1] ring structures (1971) (1)
In Reply: Information Storage (1985) (1)
Carboxylmethyl esterase of bacterial chemotaxis. (1984) (1)
Cassette principles. (1987) (1)
21 – Chemical Sensing by Bacteria (1981) (1)
New Year's Resolutions and the Black Bear. (1986) (1)
Get-rich-quick science. (1993) (1)
Insomnia and the pious parchment pile. (1987) (1)
The AIDS issue. (1988) (1)
Response: rejection and revolution. (1987) (1)
Response:Homo photosyntheticus: reaction (1988) (1)
Waste not, want some. (1991) (1)
A molecular model for the regulatory behavior of enzymes. (1971) (1)
The DNA fingerprint story (continued) (1994) (1)
Vaccines: a study in contrasts. (1994) (1)
Reversal ofFlagellar Rotation inMonotrichous and Peritrichous Bacteria: Generation ofChanges inDirection (1974) (1)
Thinking tough. (1988) (1)
Overhead and symbiosis. (1986) (1)
A serious parlor game. (1986) (1)
Pharmacia Biotech & Science Prize (1995) (1)
[Induced conformational changes in enzyme control (author's transl)]. (1973) (1)
The path to research prioritization. (1994) (1)
Science in Japan: a status report. (1986) (1)
The land of the dammed. (1991) (1)
The career of scientific exploration. (1993) (1)
Homo photosyntheticus. (1988) (1)
War and Science (1991) (1)
A "one license--one hearing" policy. (1986) (1)
New Year's Resolutions, 1995. (1995) (1)
Ice minus and jobs minus. (1987) (1)
Minorities in science. (1993) (1)
A new feature in science. (1985) (1)
IMIDAZOLE CATALYSIS OF ALKYL ESTER HYDROLYSIS AND ITS RELATION TO CHYMOTRYPSIN ACTION. (1964) (1)
A METHOD FOR DETECTING DISULFIDE INTERCHANGES IN PROTEIN MODIFICATION STUDIES. (1964) (1)
The Biochemistry of Adenosylmethionine. Francesco Salvatore , Ernest Borek , Vincenzo Zappia , Howard Guy Williams-Ashman , Fritz Schlenk (1978) (1)
Molecular advances in diseases. (1992) (1)
A good word for delusions. (1985) (1)
The Howard Hughes Medical Institute. (1988) (1)
For whom the bell tolls (1988) (1)
Molecular cloning and amplification of the adenylate cyclase gene ( cyclic AMP / overproduction ) (1)
The specificity of subunit interactions. (1977) (1)
A physical organic approach to enzymatic mechanisms. (1954) (1)
Transmission of regulatory conformational changes through proteins. (1987) (1)
1989 New Year's Resolution: Go to Heaven. (1989) (1)
Response: accuracy and truth. (1987) (1)
Cooperative Phenomena in Yeast Glyceraldehyde-3-Phosphate Dehydrogenase (1970) (1)
Propagating Conformational Changes Over Long (And Short) Distances (2001) (1)
Job application. (1992) (1)
Frontiers in plant biology. (1990) (1)
Anomalous behavior patterns (1986) (1)
Wall effects in studies of bacterial behavior (1985) (1)
Paradise gained. (1994) (0)
Design of Active-Site-Directed Irreversible Enzyme Inhibitors. The Organic Chemistry of the Enzymic Active-Site. B. R. Baker. Wiley, New York, 1967. xvi + 325 pp., illus. $13.50 (1968) (0)
Response : Biotechnology Regulation (1986) (0)
The future of biomedical sciences: introductory remarks. (1976) (0)
Conflict of interest. (1990) (0)
A good word for realities. (1985) (0)
The budget for motherhood. (1987) (0)
BIOCHEMIISTRY : COOK AND KOSHLAND enzymes from E (0)
SOSS: Save Our Social Security (1995) (0)
CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' WITH CHYMOTRYPSIN INHIBITOR 2 (2004) (0)
Methylation and phosphorylation in bacterial chemotaxis (1988) (0)
The laws of sociodynamics. (1990) (0)
The E. coli cheC gene and a new adjacent flagellar gene: Sequence and behavioral data (1985) (0)
Molecular Cloning ofChemotaxis GenesandOverproduction ofGeneProducts intheBacterial Sensing System (1981) (0)
In reply: the overhead question. (1990) (0)
Stolen Slides (2005) (0)
Response : Livermore Lab Head (1994) (0)
Letter to Floyd Bloom, Editor-in-Chief-Elect (1995) (0)
The Enzyme Molecule.W. Ferdinand (1978) (0)
Stealing success (1983) (0)
PROCEDURE FOR THE DETERMINATION OF PLUTONIUM IN URINE. Problem Assignment CX3-4 (1946) (0)
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 Y61A mutant (2004) (0)
Enzyme Specificity: Design of Active-Site-Directed Irreversible Enzyme Inhibitors . The Organic Chemistry of the Enzymic Active-Site. B. R. Baker. Wiley, New York, 1967. xvi + 325 pp., illus. $13.50. (1968) (0)
Probing the structure of the cytoplasmic domain of the aspartate receptor by targeted disulfide cross-linking. (1997) (0)
The Opportunity Connection (1995) (0)
Habituation in the single cell : Diminished secretion of norepinephrine with repetitive depolarization of PC 12 cells ( memory / protein phosphorylation / protein kinase C / phorbol esters / calciWum ) (0)
DISPLACEMENT MECHANISMS IN ENZYMATIC REACTIONS. ALKALINE PHOSPHATASE (1953) (0)
Individual-initiated public policy. (1992) (0)
The leupeptin-trypsin covalent complex at 1.14 A resolution (2006) (0)
Results and discussion in an election year. (1988) (0)
Techniques and strategies of verification. (1987) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 T58P mutant (2005) (0)
The Nature of Life: Classical and Contemporary Perspectives from Philosophy and Science: The seven pillars of life (2010) (0)
Retroactive prophets. (1987) (0)
Response : Issue Numbers and Librarianship (1986) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 T58A mutant (2005) (0)
The software review section. (1986) (0)
In reply: molecule of the year. (1990) (0)
Moderation in science budgeting. (1993) (0)
Noitall seeks new horizons. (1995) (0)
Response : Alar: the Aftermath (1992) (0)
Response : Peer Review or "Performance Review"? (1993) (0)
A scientific approach to governing. (1993) (0)
Beauty, balance, and mathematics. (1986) (0)
Response : Postal Service Here and Abroad (1991) (0)
of the AcrB Multidrug Efflux Pump Structural Basis of Multiple Drug-Binding Capacity (2007) (0)
Adding charisma to science. (1992) (0)
Letter from Daniel E. Koshland, Jr., Science Magazine to Joshua Lederberg (1988) (0)
Science puts its best foot forward. (1991) (0)
Book Reviews. Catalysis in Chemistry and Enzymology (1970) (0)
Self-esteem through fantasy. (1993) (0)
Errata (1954) (0)
Response : Math Problems (1991) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R62A mutant (2005) (0)
Basic research (II): Organization (1993) (0)
Response:science "gender-blind"? (1988) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60S mutant (2005) (0)
Enzyme Specificity. (Book Reviews: Design of Active-Site-Directed Irreversible Enzyme Inhibitors. The Organic Chemistry of the Enzymic Active-Site) (1968) (0)
Response : The Insanity Defense and Mental Illness (1992) (0)
Regulation of neurosecretory habituation in PC 12 cells : Parallel pathways used by cAMP and calcium ( memory / Iearning / secretion / adenosine / guanine nudeotide binding protein ) (0)
Response: Asteroid or Volcano: Have the Volcanists Been Heard? (1993) (0)
Three good choices. (1993) (0)
Response : Career "Choice" (1994) (0)
guanidinobenzoyl-trypsin acyl-enzyme at 1.13 A resolution (2006) (0)
Response : The Ice-Minus Case and a Scientifically Informed Judiciary (1987) (0)
Women in science (1992) (0)
In reply: marx misstated. (1990) (0)
Communism, capitalism, and dissent. (1989) (0)
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59k mutant (2004) (0)
RETROSPECTIVE: Scientist, Mentor, Colleague, and Friend -Eleanore Butz (1909-2002) (2002) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R65A mutant (2005) (0)
Response: The Ice-Minus Case and a Scientifically Informed Judiciary (1987) (0)
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59Y mutant (2004) (0)
Response : Human Genome Program (1989) (0)
The best of times, the worst of times. (1991) (0)
In Reply: Promotion of the Human Genome Project (1990) (0)
William d. Carey. (1987) (0)
Crystal Structure of the Complex of Subtilisin BPN' with Chymotrypsin Inhibitor 2 at 1.5 Angstrom Resolution (2002) (0)
ANALYSIS OF POTASSIUM AND SODIUM SOLUTIONS. Problem Assignment No. CX3-4. DEVELOPMENT OF RADIOCHEMICAL ANALYTICAL PROCEDURES FOR PLUTONIUM (1945) (0)
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59A mutant (2004) (0)
Models in Proteins Containing Subunits * (0)
Biochemistry : Dafforn and Koshland TABLE 1 . Calculation of partition functions and steric factors at 265 Ca Ground states MeOHb + HCOOHC (0)
Interview with a disaster expert. (1989) (0)
A curve-fitting procedure for the study of the binding of small molecules to multi-subunit proteins. (1970) (0)
Response: Balance in Science (1989) (0)
Random samples. (2021) (0)
Peer Review (2013) (0)
Progress in Japanese science. (1994) (0)
Response : Molecule of the Year (1990) (0)
Frontiers in neuroscience. (1993) (0)
Inexorable laws and the ecosystem. (1987) (0)
Evidence for an Intermediate in Myosin Hydrolysis (1962) (0)
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59K, in pH 9 cryosoak (2004) (0)
The perversity of inanimate objects. (1994) (0)
Andrei sakharov, 1921-1989. (1990) (0)
Excitatory amino acid uptake and N-methyl-D-aspartate-mediated secretion in a neural cell line ( N-methyl-D-aspartate receptor / neurosecretion / 2-amino-4-phosphonobutyrate / phorbol esters / protein kinase C ) (0)
Philip hauge abelson. (1985) (0)
Response : Balance in Science (1989) (0)
Time-resolved intermediate trapping and X-ray crystallographic studies of enzyme mechanism: Isocitrate dehydrogenase and nuclease catalysts (1999) (0)
Response : Preventing Fraud (1989) (0)
crystal structure of the complex of subtilsin BPN'with chymotrypsin inhibitor 2 M59G mutant (2004) (0)
Response : The Genome Project: Pro and Con (1990) (0)
Epidemics and civil rights. (1987) (0)
Response : Asteroid or Volcano: Have the Volcanists Been Heard? (1993) (0)
Defining Hysteretic Enzymes (2001) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60A mutant (2005) (0)
In reply: resources and compromise. (1985) (0)
Steric effects in enzymatic reactions (1997) (0)
An amplified sensitivity arising fro biological systems (protein modification/metabolic regulation/switch mechanism/enzyr (1981) (0)
PRODUCTION OF "LIGHT" ISOTOPES IN A HOMOGENEOUS PILE (1946) (0)
Science in Japan (1992) (0)
" SOlE MOE AMERICAN ASSOCIATION FOR THE ADVANCEMENT (0)
An inspiring leadership toward improving global health (2001) (0)
The saving of yosemite. (1991) (0)
Response : Resources and Compromise (1985) (0)
Biological Systems: Papers from Science, 1988-1989 (1990) (0)
NIH budget and better health. (1985) (0)
The perfect money management system. (1988) (0)
Response : The Overhead Question (1990) (0)
The reader response: oyvey. (1993) (0)
Response : Marx Misstated (1990) (0)
A campaign for science. (1992) (0)
Response : Promotion of the Human Genome Project (1990) (0)
NIH Budget and Better Health (1985) (0)
A four location model to explain the stereospecificity of proteins. (2003) (0)
Where the grass is rougher and greener. (1992) (0)
Response (1991) (0)
RELATION TO NEUROBIOLOGY (1980) (0)
Methodology and theory at the frontier. (1992) (0)
Frontiers in recombinant DNA. (1987) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59R/E60S mutant (2005) (0)
Response : Is Science "Gender-Blind"? (1988) (0)
THE ACTIVE CENTER IN ENZYME ACTION. (1964) (0)
The AAAS Observer. (1988) (0)
SUBUNIT INTERACTIONS IN ALLOSTERIC CONTROL (1972) (0)
In Reply: The Genome Project: Pro and Con (1990) (0)
National Institutes of Health: the centennial year. (1987) (0)
Educating the best and employing them. (1994) (0)
Stochasticism in Physics, Chemistry and Biology (1997) (0)
HETEROGENEOUS CATALYSIS OF HYDROGEN PEROXIDE DECOMPOSITION. Problem Assignment No. CX5-1 (1946) (0)
A department of science? (1985) (0)
crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59F mutant (2004) (0)
Cooperative phenomena and conformational changes. (1967) (0)
Kaposi's sarcoma, vascular permeability, and scientific integrity. (1994) (0)
Solubilization of certain L- and D-Peptidases of hog kidney particulates. (1952) (0)
Receptor structure in the bacterial sensing system ( chemotaxis / membranes / serine receptor / aspartate receptor / methyl-accepting chemotaxis proteins ) (0)
Sound bites versus sound thinking. (1990) (0)
Biology of the Chemotactic Response edited by J. M. Lackie and P. C. Wilkinson, Cambridge University Press, 1982. £8.95 (xiii + 177 pages) ISBN 0 521 29897 0 (1982) (0)
Biological systems. (1988) (0)
Response : Rejection and Revolution (1987) (0)
Homo photosyntheticus: Reaction: Response (1988) (0)
Response : Accuracy and Truth (1987) (0)
The winds of change. (1986) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 F69A mutant (2005) (0)
New Year's Resolutions and Future Shock. (1991) (0)
Mechanisms of organic and enzymic reactions (Waley, S, G,) (1962) (0)
Response : Speaking Out (1993) (0)
Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R67A mutant (2005) (0)
Response : Journal Policies on Conflict of Interest (1993) (0)
Response: biotechnology regulation. (1986) (0)
succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution (2006) (0)
Frank H. Westheimer (1912–2007) (2007) (0)

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