David E. L. Wilcken
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David E. L. Wilckenbiology Degrees
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Molecular Biology
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Biochemistry
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Biology
Why Is David E. L. Wilcken Influential?
(Suggest an Edit or Addition)David E. L. Wilcken's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Common methylenetetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease: the result of a meta-analysis. (1998) (733)
- The pathogenesis of coronary artery disease. A possible role for methionine metabolism. (1976) (553)
- Homocysteine and cardiovascular disease: cause or effect? (2000) (446)
- The effect of weight reduction on left ventricular mass. A randomized controlled trial in young, overweight hypertensive patients. (1986) (354)
- Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. (1997) (314)
- Vascular Outcome in Patients With Homocystinuria due to Cystathionine &bgr;-Synthase Deficiency Treated Chronically: A Multicenter Observational Study (2001) (249)
- Homocystinuria--the effects of betaine in the treatment of patients not responsive to pyridoxine. (1983) (230)
- Homocysteine and its disulfide derivatives: a suggested consensus terminology. (2000) (227)
- Disordered methionine/homocysteine metabolism in premature vascular disease. Its occurrence, cofactor therapy, and enzymology. (1993) (217)
- Folic acid lowers elevated plasma homocysteine in chronic renal insufficiency: possible implications for prevention of vascular disease. (1988) (195)
- Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation. (1996) (194)
- The natural history of vascular disease in homocystinuria and the effects of treatment (1997) (174)
- Collagen composition of normal and myxomatous human mitral heart valves. (1984) (169)
- Effects of Alterations in Aortic Impedance on the Performance of the Ventricles (1964) (163)
- Homocysteinemia, ischemic heart disease, and the carrier state for homocystinuria. (1983) (149)
- Determinants of severity of coronary artery disease in Australian men and women. (1994) (142)
- Polymorphisms of the apolipoprotein E gene and severity of coronary artery disease defined by angiography. (1995) (121)
- Homocysteine in the plasma of renal transplant recipients: effects of cofactors for methionine metabolism. (1981) (118)
- Vascular complications of severe hyperhomocysteinemia in patients with homocystinuria due to cystathionine beta-synthase deficiency: effects of homocysteine-lowering therapy. (2000) (114)
- Human arterial endothelial cell detachment in vitro: its promotion by homocysteine and cysteine. (1991) (111)
- Relationship between total plasma homocysteine, polymorphisms of homocysteine metabolism related enzymes, risk factors and coronary artery disease in the Australian hospital-based population. (1999) (108)
- Plasma extracellular superoxide dismutase levels in an Australian population with coronary artery disease. (1998) (106)
- Stroke volume in conscious dogs; effect of respiration, posture, and vascular occlusion. (1965) (105)
- The Glu-298→Asp (894G→T) mutation at exon 7 of the endothelial nitric oxide synthase gene and coronary artery disease (1999) (103)
- Accumulation of sulphur-containing amino acids including cysteine-homocysteine in patients on maintenance haemodialysis. (1980) (95)
- Lifetime risk for patients with mitral valve prolapse of developing severe valve regurgitation requiring surgery. (1988) (95)
- Circulating lipid hydroperoxide levels in human hyperhomocysteinemia. Relevance to development of arteriosclerosis. (1993) (90)
- Common DNA polymorphisms at the lipoprotein lipase gene. Association with severity of coronary artery disease and diabetes. (1996) (88)
- Homocystinuria due to cystathionine beta-synthase deficiency--the effects of betaine treatment in pyridoxine-responsive patients. (1985) (87)
- Decreases in apolipoprotein(a) after renal transplantation: implications for lipoprotein(a) metabolism. (1992) (86)
- Primary (spontaneous) chordal rupture: relation to myxomatous valve disease and mitral valve prolapse. (1985) (86)
- Mitral valve prolapse and bacterial endocarditis: when is antibiotic prophylaxis necessary? (1984) (82)
- Polymorphisms of factor V, factor VII, and fibrinogen genes. Relevance to severity of coronary artery disease. (1997) (81)
- Regional left ventricular wall motion assessment: comparison of two-dimensional echocardiography and radionuclide angiography with contrast angiography in healed myocardial infarction. (1985) (81)
- Human homocysteine catabolism: three major pathways and their relevance to development of arterial occlusive disease. (1996) (81)
- Cigarette smoke activates caspase-3 to induce apoptosis of human umbilical venous endothelial cells. (2001) (80)
- Asymmetric dimethylarginine (ADMA) in vascular, renal and hepatic disease and the regulatory role of L-arginine on its metabolism. (2007) (78)
- Relationship between homocysteine and superoxide dismutase in homocystinuria: possible relevance to cardiovascular risk. (2000) (77)
- Interrelations between plasma free and protein-bound homocysteine and cysteine in homocystinuria. (1988) (74)
- Evidence for intravenous dipyridamole (persantin) producing a "coronary steal" effect in the ischaemic myocardium. (1971) (72)
- Angiotensin-converting enzyme genotype in children and coronary events in their grandparents. (1995) (68)
- Homocysteine thiolactone disposal by human arterial endothelial cells and serum in vitro. (1991) (68)
- Lipoprotein(a) and apolipoproteins B and A-1 in children and coronary vascular events in their grandparents. (1993) (66)
- Cysteine-homocysteine mixed disulphide: differing plasma concentrations in normal men and women. (1979) (64)
- Obliterative Pulmonary Hypertension and Thrombo-embolism* (1963) (64)
- Risk of infective endocarditis in mitral valve prolapse with and without precordial systolic murmurs. (1987) (64)
- Reactive hyperaemia in the dog heart: inter-relations between adenosine, ATP, and aminophylline and the effect of indomethacin. (1977) (61)
- Polymorphisms at the 5'-end of the apolipoprotein AI gene and severity of coronary artery disease. (1996) (61)
- Reactive Hyperemia in the Dog Heart: Effects of Temporarily Restricting Arterial Inflow and of Coronary Occlusions Lasting One and Two Cardiac Cycles (1974) (57)
- Homocysteine catabolism: levels of 3 enzymes in cultured human vascular endothelium and their relevance to vascular disease. (1992) (55)
- MTHFR 677C→T mutation, folate intake, neural-tube defect, and risk of cardiovascular disease (1997) (54)
- Age and the clinical profile of idiopathic mitral valve prolapse. (1986) (54)
- Glucagon in Heart Failure and in Cardiogenic Shock: Experience in 50 Patients (1972) (53)
- Circulating transforming growth factor beta 1 and coronary artery disease. (1997) (48)
- Early expression of the apolipoprotein (a) gene: relationships between infants' and their parents' serum apolipoprotein (a) levels. (1992) (48)
- Genotype distribution of angiotensin-converting enzyme polymorphism in Australian healthy and coronary populations and relevance to myocardial infarction and coronary artery disease. (1996) (46)
- INCISIONAL ANEURYSMS OF THE LEFT VENTRICLE (1961) (44)
- Growth hormone increases and insulin-like growth factor-I decreases circulating lipoprotein(a) (1997) (42)
- The electrocardiogram in chronic bronchitis with generalized obstructive lung disease. Its relation to ventilatory function. (1962) (40)
- Independence of mitral valve prolapse and neurosis. (1983) (39)
- Homocysteine thiolactone and experimental homocysteinemia. (1982) (38)
- Increased plasma copper in patients with homocystinuria due to cystathionine beta-synthase deficiency. (1983) (37)
- A twin study of polycystic ovary syndrome and lipids. (1997) (37)
- L-arginine regulates asymmetric dimethylarginine metabolism by inhibiting dimethylarginine dimethylaminohydrolase activity in hepatic (HepG2) cells (2006) (37)
- Myocardial Reactive Hyperemia and Coronary Vascular Reactivity in the Dog (1973) (36)
- MspI polymorphism in the promoter of the human endothelial constitutive NO synthase gene in Australian Caucasian population. (1998) (35)
- Anticoagulant treatment of obliterative pulmonary hypertension. (1960) (35)
- Changes in the immunoreactivity of Apo A-I during storage. (1989) (34)
- Experimental homocysteinemia in pigs: comparison with studies in sixteen homocystinuric patients. (1982) (34)
- A Comparison of the Pulmonary Blood Flow between Left and Right Lungs in Normal Subjects and Patients with Congenital Heart Disease (1961) (33)
- Cytomegalovirus inhibits p53 nuclear localization signal function (2001) (32)
- Influence of an inducible nitric oxide synthase promoter variant on clinical variables in patients with coronary artery disease. (2001) (32)
- Screening for Familial Hypercholesterolemia in 5000 Neonates: A Recall Study (1988) (31)
- An indirect sandwich ELISA for LP(a) in serum and dried blood spots. (1992) (31)
- Homocystinuria and Atherosclerosis (1992) (30)
- Glucagon in resistant heart-failure and cardiogenic shock. (1970) (29)
- Reserpine: Effect on Structure of Heart Muscle (1967) (29)
- Methylenetetrahydrofolate reductase (MTHFR) mutation, homocyst(e)ine, and coronary artery disease. (1997) (29)
- Homocysteinemia: depressed plasma serine levels. (1987) (28)
- Enzyme-linked immunosorbent assay of apolipoprotein B in blood spotted onto filter paper, suitable for neonatal screening. (1989) (27)
- Insulin-like growth factor-I decreases serum lipoprotein (a) during long-term treatment of patients with Laron syndrome. (1996) (27)
- Mechanisms of thrombogenesis and accelerated atherogenesis in homocysteinaemia. (1989) (26)
- A common polymorphism of the transforming growth factor-beta1 gene and coronary artery disease. (1998) (26)
- Dose-dependent effects of folic acid on plasma homocysteine in a randomized trial conducted among 723 individuals with coronary heart disease. (2002) (26)
- Free and protein-bound homocysteine and cysteine in cystathionine beta-synthase deficiency: interrelations during short- and long-term changes in plasma concentrations. (1989) (25)
- The inhibition of adenosine phosphorylation in platelets by dipyridamole. (1971) (24)
- Radial immunodiffusion assay of apolipoprotein B in blood dried on filter paper--a potential screening method for familial type II hypercholesterolaemia. (1985) (24)
- Polymorphism in the gelatinase B gene and the severity of coronary arterial stenosis. (2001) (24)
- Histamine Receptors in the Coronary Circulation of the Dog: Effects of Mepyramine and Metiamide on Responses to Histamine Infusions (1977) (23)
- Homocysteine and cardiovascular disease : cause or effect ? 1 , 2 (23)
- 1H NMR determination of urinary betaine in patients with premature vascular disease and mild homocysteinemia. (1995) (23)
- Neonatal apo A-I, apo B, and apo(a) Levels in Dried Blood Spots in an Australian Population (1990) (23)
- LOAD, WORK, AND VELOCITY OF MUSCLE SHORTENING OF THE LEFT VENTRICLE IN NORMAL AND ABNORMAL HUMAN HEARTS. (1965) (22)
- Asymmetric dimethylarginine in homocystinuria due to cystathionine β-synthase deficiency: Relevance of renal function (2006) (22)
- The effect of dipyridamole and of aminophyline on responses to sixty-second coronary artery occlusions in dogs. (1973) (21)
- Overview of inherited metabolic disorders causing cardiovascular disease (2003) (21)
- Physiology of the Normal Heart (2002) (21)
- Ultrastructural evidence for regeneration of heart--muscle cells after experimental myocardial infarction. (1970) (21)
- Myocardial reactive hyperaemia in conscious dogs: effect of dipyridamole and aminophylline on responses to four- and eight-second coronary artery occlusions. (1973) (20)
- Diversity of Cystathionine β-Synthase Haplotypes Bearing the Most Common Homocystinuria Mutation c.833T>C: A Possible Role for Gene Conversion (2006) (20)
- Betaine:homocysteine methyltransferase--a new assay for the liver enzyme and its absence from human skin fibroblasts and peripheral blood lymphocytes. (1991) (19)
- The effect on transcription efficiency of the apolipoprotein AI gene of DNA variants at the 5′ untranslated region (1998) (18)
- Polymorphism in the gelatinase B gene and the severity of coronary arterial stenosis (2001) (18)
- Variables Affecting Apolipoprotein B Measurements in 3- to 5-Day-Old Babies: A Study of 4491 Neonates (1987) (18)
- C to T and/or G to A transitions are responsible for loss of a MspI restriction site at the 5′-end of the human apolipoprotein AI gene (1995) (18)
- Reliability and clinical relevance of detection of vegetations by echocardiography in bacterial endocarditis. (1981) (17)
- AN ENZYME‐IMMUNOASSAY FOR MYOGLOBIN IN HUMAN SERUM AND URINE. METHOD DEVELOPMENT, NORMAL VALUES AND APPLICATION TO ACUTE MYOCARDIAL INFARCTION (1979) (17)
- Mitral Valvotomy and Restenosis (1960) (15)
- Interactive effect of the p53 gene and cigarette smoking on coronary artery disease. (1997) (15)
- DYE DILUTION CURVES IN CONGENITAL HEART DISEASE (1960) (15)
- Comparison of serum myoglobin and creatine kinase MB isoenzyme in early diagnosis of acute myocardial infarction. (1981) (15)
- Excretion of myoglobin in urine after actue myocardial infarction. (1977) (15)
- Growth Hormone Treatment Increases Circulating Lipoprotein(a) in Children with Chronic Renal Failure (1996) (14)
- The relationship between infant and parent Lp(a) levels. (1994) (13)
- Bodily habitus and mitral valve prolapse. (1985) (13)
- Apolipoproteins A-I and B and the B/A-I Ratio in the First Year of Life (1991) (13)
- Lp(a) and conventional risk profiles predict the severity of coronary stenosis in high-risk hospital-based patients. (2000) (13)
- Local factors controlling coronary circulation. (1983) (13)
- M-mode echocardiography: reproducibility of serial left ventricular measurements in subjects with normal ventricles and patients with congestive cardiomyopathy. (1983) (13)
- Genetic polymorphism of heparan sulfate proteoglycan (perlecan, HSPG2), lipid profiles and coronary artery disease in the Australian population. (2000) (12)
- Genes, gender and geometry and the prolapsing mitral valve. (1992) (12)
- THE ACTION OF AMINOPHYLLINE ON THE ACUTELY TRANSPLANTED DOG HEART: EFFECT OF α‐ AND β‐ADRENOCEPTOR BLOCKADE (1975) (11)
- A CASE OF MYELOID RETICULOSIS (1957) (11)
- Homocysteine, smoking and vascular disease. (2002) (11)
- Mechanisms responsible for increasing immunoreactivity of apolipoprotein A-I with storage: the role of oxidation. (1989) (11)
- Histamine Receptors in the Coronary Circulation of the Dog (1976) (10)
- The Apo A, B, a of coronary risk: back to kindergarten. (1992) (10)
- Obliterative Pulmonary Hypertension and Thrombo-embolism* (1963) (9)
- Inter-relations between the actions of dipyridamole, adenosine, aminophylline and propranolol on the coronary circulation of the transplanted dog heart. (1971) (9)
- THE MEASUREMENT OF THE END-DIASTOLIC AND END-SYSTOLIC, OR RESIDUAL, VOLUMES OF THE LEFT VENTRICLE IN MAN, USING A DYE-DILUTION METHOD. (1965) (9)
- Association between an angiotensinogen microsatellite marker in children and coronary events in their grandparents. (1996) (9)
- The elecrocardiogram in diffuse interstitial disease of the lung and its relation to pulmonary function. (1962) (9)
- An unusual infection after renal transplantation (1986) (8)
- Plasma levels of extracellular superoxide dismutase in an Australian population: genetic contribution to normal variation and correlations with plasma nitric oxide and apolipoprotein A-I levels. (2000) (8)
- Changes of allele-specific expression of apo(a) gene in infants during first year of life (1992) (7)
- Smoking: a major predictor of left ventricular function after occlusion of the left anterior descending coronary artery. (1986) (7)
- Studies on the Coronary Circulation during Rejection of the Heterotopically Transplanted Dog Heart (1973) (7)
- A neonatal screening approach to the detection of familial hypercholesterolaemia and family-based coronary prevention (1988) (7)
- THE DETECTION OF MYOGLOBIN IN URINE AND ITS APPLICATION TO THE DIAGNOSIS OF MYOCARDIAL INFARCTION (1976) (7)
- Failure to detect homocysteine in the acid-hydrolysed plasmas of recent myocardial infarct patients. (1991) (6)
- Historical Aspects of the Relationship between Homocysteine and Vascular Disease (2000) (6)
- Excretion of myoglobin in urine after cardiac catheterisation. (1978) (5)
- The Long-Term Outcome in Homocystinuria (1997) (5)
- The effect of prolonged glucagon infusions on the urinary excretion of catecholamines and 4-hydroxy-3-methoxymandelic acid and on adrenal medullary tissue levels of catecholamines in patients with severe cardiac disease. (1974) (5)
- Effect of Reserpine on the Structure of Heart Mitochondria and the Relation to Catecholamine Depletion (1967) (5)
- Reactive hyperaemia in the dog heart: studies on mechanisms. (1974) (5)
- Left ventricular volume in man: the relation to heart rate and to end-diastolic pressure. (1968) (4)
- A sluicing device for reproducibly measuring the strength of attachment of cultured cells to their substrate. (1987) (4)
- Echocardiography in left atrial myxoma: relation to the findings in mitral stenosis. (1972) (4)
- Effects of catecholamines on the coronary circulation in the Langendorff-type transplanted dog heart. (1975) (4)
- Clinical physiology of the normal heart (2010) (4)
- The Detection of Cysteine-Homocysteine Mixed Disulphide in Fasting Plasma of Normal Man and the Difference in Levels Found between Men and Women (1978) (3)
- The effects of homocysteine on the attachment of human arterial endothelial cells (1985) (3)
- The effects of 2,6-bis(diethanolamino)-4-piperidino-pyrimido(5,4-D)pyrimidine (RA233) on the coronary circulation of the acutely transplanted dog heart: comparison with dipyridamole and adenosine. (1972) (3)
- Cross sectional visualization of the normal heart by the UI octoson (1978) (2)
- The role of echocardiography in the assessment of chronic aortic regurgitation. (1977) (2)
- The attachment and detachment of human endothelial cells (1986) (2)
- EFFECT OF L.A.D. OCCLUSION ON LEFT VENTRICULAR FUNCTION (1982) (1)
- Basic sciencePhysiology of the normal heart (2015) (1)
- Interactive effect of the p 53 gene and cigarette smoking on coronary artery disease (1997) (1)
- Percutaneous angioplasty in the management of renovascular hypertension. (1982) (1)
- Reply to R Cerone et al (2001) (1)
- ECHOCARDIOGRAPHIC FEATURES OF HYPERTROPHIC CARDIOMYOPATHY (1977) (1)
- Cardiac tumour. An echocardiographic diagnosis. (1982) (1)
- The P wave axis in pulmonary diseas (1962) (0)
- Polymorphisms at the 5 9-End of the Apolipoprotein AI Gene and Severity of Coronary Artery Disease (2013) (0)
- Comparison ofserummyoglobin andcreatine kinase MB isoenzyme inearly diagnosis ofacute myocardial infarction (1981) (0)
- Views on diet, cholesterol inhibition, and long-term anticoagulants in ischaemic heart disease. (1963) (0)
- EFFECT OF RACE ON LIPOPROTEIN PROFILE. AUTHOR'S REPLY (1994) (0)
- Reply to “Cardiovascular disease risk” (1996) (0)
- Deficiency Treated Chronically : A Multicenter Observational Study-Synthase β Vascular Outcome in Patients With Homocystinuria due to Cystathionine (2001) (0)
- Determinants of severity of left ventricular dysfunction in Australian men and women with coronary disease aged 65 years or less. (1995) (0)
- Colloquium: Homocyst(e)ine, Vitamins and Arterial Occlusive Diseases Human Homocysteine Catabolismi Three Major Pathways and Their Relevance to Development of Arterial Occlusive Disease1'2 (1996) (0)
- ECHOCARDIOGRAPHY IN AORTIC VALVE DISEASE (1977) (0)
- Apolipoprotein screening in Australian children (1998) (0)
- Proceedings: Reactive hyperaemia in the dog heart: assessment of post-hyperaemic coronary vascular reactivity and of the effects of temporarily restricting arterial inflow. (1973) (0)
- THE CLINICAL APPLICATIONS OF TWO–DIMENSIONAL ECHOCARDIOGRAPHY (1977) (0)
- Cross Sectional Imaging of the Heart by the UI Octoson (1978) (0)
- Homocysteine in Chronic Renal Insufficiency: Possible Relevance to the Pathogenesis of Premature Atherosclerosis (1980) (0)
- OBSERVATIONS ON RESTENOSIS AND UPON CORONARY EMBOLISM AND ANGINA IN MITRAL VALVE DISEASE. (1963) (0)
- The action of aminophylline on the acutely transplanted dog heart: effect of alpha- and beta-adrenoceptor blockade. (1975) (0)
- The cal ultrasonic cardioscope (2006) (0)
- Non-lipid models of human vascular disease (1986) (0)
- Reply to: Effect of race on lipoprotein profile (1994) (0)
- The Human Pulmonary Circulation: Its Form and Function in Health and Disease (1979) (0)
- C ysteine-homocysteine mixed disulphide : differing plasma concentrations in normal men and women (2012) (0)
- COMPARATIVE ASSESSMENT OF REGIONAL WALL MOTION BY TWO DIMENSIONAL ECHOCARDIOGRAPHY, RADIONUCLIDE ANGIOGRAPHY and CONTRAST VENTRICULOGRAPHY (1982) (0)
- ONE–DAY COURSE IN ECHOCARDIOGRAPHY: POSTGRADUATE COMMITTEE IN MEDICAL EDUCATION THE UNIVERSITY OF NEW SOUTH WALES: INTRODUCTORY STATEMENT (1977) (0)
- Excretion of myoglobin in urine after cardiac (0)
- ECHOCARDIOGRAPHY AND LEFT VENTRICULAR FUNCTION (1977) (0)
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