Denis G. Baskin
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Biology
Denis G. Baskin's Degrees
- PhD Physiology University of California, San Francisco
- Bachelors Biology University of California, Santa Cruz
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(Suggest an Edit or Addition)Denis G. Baskin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Central nervous system control of food intake (2000) (6177)
- Central nervous system control of food intake and body weight (2006) (2297)
- Identification of targets of leptin action in rat hypothalamus. (1996) (1570)
- Obesity is associated with hypothalamic injury in rodents and humans. (2012) (1404)
- Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons (1998) (1132)
- Specificity of Leptin Action on Elevated Blood Glucose Levels and Hypothalamic Neuropeptide Y Gene Expression in ob/ob Mice (1996) (912)
- Leptin Increases Hypothalamic Pro-opiomelanocortin mRNA Expression in the Rostral Arcuate Nucleus (1997) (908)
- Insulin in the brain: a hormonal regulator of energy balance. (1992) (846)
- Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats (2002) (684)
- Inhibition of hypothalamic neuropeptide Y gene expression by insulin. (1992) (573)
- Melanocortin receptors in leptin effects (1997) (524)
- Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. (2009) (522)
- Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. (2003) (481)
- Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat (2003) (457)
- Localization of insulin receptor mRNA in rat brain by in situ hybridization. (1990) (431)
- Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight (1999) (416)
- Evidence that the caudal brainstem is a target for the inhibitory effect of leptin on food intake. (2002) (387)
- Effect of Intracerebroventricular Insulin Infusion on Diabetic Hyperphagia and Hypothalamic Neuropeptide Gene Expression (1995) (386)
- Insulin in the brain. (1987) (377)
- Is the energy homeostasis system inherently biased toward weight gain? (2003) (376)
- Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus. (1999) (358)
- Food intake and the regulation of body weight. (2000) (344)
- Insulin and insulin-like growth factors in the CNS (1988) (343)
- Insulin signaling in the central nervous system: a critical role in metabolic homeostasis and disease from C. elegans to humans. (2005) (340)
- Insulin and the blood-brain barrier. (2003) (318)
- Evidence that paraventricular nucleus oxytocin neurons link hypothalamic leptin action to caudal brain stem nuclei controlling meal size. (2004) (307)
- Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety. (2009) (296)
- Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide. (1996) (280)
- Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats. (1996) (271)
- Central insulin administration reduces neuropeptide Y mRNA expression in the arcuate nucleus of food-deprived lean (Fa/Fa) but not obese (fa/fa) Zucker rats. (1991) (260)
- Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis (2004) (249)
- Leptin action in the forebrain regulates the hindbrain response to satiety signals. (2005) (239)
- Leptin and insulin action in the central nervous system. (2002) (239)
- Model for the regulation of energy balance and adiposity by the central nervous system. (1995) (215)
- Leptin Receptor Long-form Splice-variant Protein Expression in Neuron Cell Bodies of the Brain and Co-localization with Neuropeptide Y mRNA in the Arcuate Nucleus (1999) (208)
- Regional concentrations of insulin in the rat brain. (1983) (206)
- Effects of Hypothalamic Neurodegeneration on Energy Balance (2005) (206)
- Obesity, diabetes and the central nervous system (1998) (192)
- Localization of binding sites for insulin-like growth factor-I (IGF-I) in the rat brain by quantitative autoradiography (1988) (186)
- Localization of 125I-insulin binding sites in the rat hypothalamus by quantitative autoradiography (1986) (186)
- Peripheral oxytocin suppresses food intake and causes weight loss in diet-induced obese rats. (2012) (186)
- Increased expression of mRNA for the long form of the leptin receptor in the hypothalamus is associated with leptin hypersensitivity and fasting. (1998) (176)
- Leptin Regulation of the Anorexic Response to Glucagon-Like Peptide-1 Receptor Stimulation (2006) (171)
- Leptin sensitive neurons in the hypothalamus. (1999) (167)
- Oxytocin innervation of caudal brainstem nuclei activated by cholecystokinin (2003) (157)
- Neuropeptide Y-like gene expression in the salmon brain increases with fasting. (1998) (154)
- Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats. (2003) (150)
- Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys. (2015) (145)
- Genetically obese Zucker rats have abnormally low brain insulin content. (1985) (142)
- Controls for Immunohistochemistry (2014) (142)
- Immunocytochemical detection of insulin in rat hypothalamus and its possible uptake from cerebrospinal fluid. (1983) (134)
- Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats. (2000) (130)
- Insulin Secretory Deficiency and Glucose Intolerance in Rab3A Null Mice* (2003) (126)
- Localization of type I insulin-like growth factor receptor messenger RNA in the adult rat brain by in situ hybridization. (1991) (126)
- Neuroendocrine mechanisms regulating food intake and body weight (2000) (121)
- Differential effect of fasting on hypothalamic expression of genes encoding neuropeptide Y, galanin, and glutamic acid decarboxylase (1993) (120)
- Hypothalamic, Metabolic, and Behavioral Responses to Pharmacological Inhibition of CNS Melanocortin Signaling in Rats (2001) (115)
- Immunocytochemical Detection of Phosphatidylinositol 3-kinase Activation by Insulin and Leptin (2003) (113)
- Characterization and localization of 3H-arginine8-vasopressin binding to rat kidney and brain tissue (1983) (112)
- Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats (1990) (112)
- Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue. (2003) (110)
- Translational and therapeutic potential of oxytocin as an anti-obesity strategy: Insights from rodents, nonhuman primates and humans (2015) (109)
- Immunocytochemistry with osmium-fixed tissue. I. Light microscopic localization of growth hormone and prolactin with the unlabeled antibody-enzyme method. (1979) (106)
- Influence of hydrogen peroxide or alcoholic sodium hydroxide on the immunocytochemical detection of growth hormone and prolactin after osmium fixation. (1979) (106)
- Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat. (2008) (104)
- Ileal interposition surgery improves glucose and lipid metabolism and delays diabetes onset in the UCD-T2DM rat. (2010) (100)
- Distribution of insulin receptor substrate-2 in brain areas involved in energy homeostasis (2006) (99)
- Quantitative Autoradiographic Evidence for Insulin Receptors in the Choroid Plexus of the Rat Brain (1986) (99)
- Selective uptake of radiolabeled annexin V on acute porcine left atrial thrombi. (1995) (98)
- CNS Melanocortin System Involvement in the Regulation of Food Intake (2000) (95)
- Brain and liver insulin binding is decreased in Zucker rats carrying the 'fa' gene. (1985) (94)
- Hypothalamic-brainstem circuits controlling eating. (2010) (92)
- Pancreatic Expression and Secretion of Human Islet Amyloid Polypeptide in a Transgenic Mouse (1994) (92)
- Effect of fasting and leptin deficiency on hypothalamic neuropeptide Y gene transcription in vivo revealed by expression of a lacZ reporter gene. (1998) (91)
- Effect of fasting on regional levels of neuropeptide Y mRNA and insulin receptors in the rat hypothalamus: An autoradiographic study (1992) (90)
- Reduced effect of experimental peripheral hyperinsulinemia to elevate cerebrospinal fluid insulin concentrations of obese Zucker rats. (1987) (89)
- Autoradiographic localization of specific binding sites for [3H][Arg8]vasopressin in the septum of the rat brain with tritium-sensitive film. (1983) (87)
- Insulin receptor substrate-1 (IRS-1) expression in rat brain. (1994) (84)
- Hypothalamic Melanin-Concentrating Hormone and Estrogen-Induced Weight Loss (2000) (81)
- Immunoreactive insulin levels are elevated in the cerebrospinal fluid of genetically obese Zucker rats. (1983) (79)
- Chronic CNS oxytocin signaling preferentially induces fat loss in high-fat diet-fed rats by enhancing satiety responses and increasing lipid utilization. (2016) (78)
- Chronic Administration of the Glucagon-Like Peptide-1 Analog, Liraglutide, Delays the Onset of Diabetes and Lowers Triglycerides in UCD-T2DM Rats (2010) (76)
- A new oxytocin-saporin cytotoxin for lesioning oxytocin-receptive neurons in the rat hindbrain. (2010) (73)
- IL-1 beta modulation of spontaneous autoimmune diabetes and thyroiditis in the BB rat. (1990) (69)
- Leptin binding in the arcuate nucleus is increased during fasting (1999) (68)
- Identification of binding sites for an insulin-like growth factor (IGF-I) in the median eminence of the rat brain by quantitative autoradiography. (1986) (68)
- Immunocytochemical detection of insulin receptor substrate-1 (IRS-1) in rat brain: colocalization with phosphotyrosine (1993) (67)
- Distribution of somatostatin-14 and somatostatin-28 gastrointestinal-pancreatic cells of rats and humans. (1990) (66)
- Forebrain melanocortin signaling enhances the hindbrain satiety response to CCK-8. (2009) (64)
- Insulin, Neuropeptide Y, and Food Intake (1993) (62)
- Localization and characterization of vasopressin-binding sites in the amygdala of the rat brain (1984) (61)
- Ontogenetic changes in vasopressin binding site distribution in rat brain: an autoradiographic study. (1986) (60)
- Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats. (2014) (59)
- SOCS-3 expression in leptin-sensitive neurons of the hypothalamus of fed and fasted rats (2000) (59)
- Characterization of insulin-like growth factor I receptors in the median eminence of the brain and their modulation by food restriction. (1988) (58)
- How the brain regulates food intake and body weight: the role of leptin. (2001) (58)
- Fundamentals of quantitative autoradiography by computer densitometry for in situ hybridization, with emphasis on 33P. (1993) (56)
- Dietary fructose accelerates the development of diabetes in UCD-T2DM rats: amelioration by the antioxidant, alpha-lipoic acid. (2010) (55)
- Metabolic, gastrointestinal, and CNS neuropeptide effects of brain leptin administration in the rat. (1999) (53)
- Evidence that vasoactive intestinal polypeptide is a parasympathetic neurotransmitter in the endocrine pancreas in dogs (1997) (51)
- Localization of the plasma membrane Ca(2+)-ATPase isoform PMCA3 in rat cerebellum, choroid plexus and hippocampus. (1995) (51)
- An inexpensive microcomputer digital imaging system for densitometry: quantitative autoradiography of insulin receptors with 125I and LKB ultrofilm (1986) (51)
- Somatostatin in epithelial cells of intestinal mucosa is present primarily as somatostatin 28 (1984) (51)
- Peptide signals regulating food intake and energy homeostasis. (2002) (50)
- Localization of insulin and type 1 IGF receptors in rat brain by in vitro autoradiography and in situ hybridization. (1991) (50)
- Immunocytochemical localization of Na+,K+ adenosine triphosphatase in the rat retina. (1984) (47)
- Heterogeneity of islet pathology in two infants with recent onset diabetes mellitus (2004) (46)
- Hindbrain leptin receptor stimulation enhances the anorexic response to cholecystokinin. (2009) (45)
- Estradiol inhibits the increase of hypothalamic neuropeptide Y messenger ribonucleic acid expression induced by weight loss in ovariectomized rats. (1995) (44)
- NPY and galanin in a hibernator: Hypothalamic gene expression and effects on feeding (1993) (42)
- High-fat diet feeding causes rapid, non-apoptotic cleavage of caspase-3 in astrocytes (2013) (41)
- Fluorescence In Situ Hybridization of Scarce Leptin Receptor mRNA using the Enzyme-Labeled Fluorescent Substrate Method and Tyramide Signal Amplification (2000) (41)
- A Historical Perspective on the Identification of Cell Types in Pancreatic Islets of Langerhans by Staining and Histochemical Techniques (2015) (40)
- Responses of Pancreatic B Cells to Alloxan and Streptozotocin in the Guinea Pig (1986) (39)
- Localization and structural characterization of insulin-like growth factor receptors in mammalian retina. (1989) (39)
- Differential detection of rat islet and brain glutamic acid decarboxylase (GAD) isoforms with sequence-specific peptide antibodies. (1995) (38)
- Histochemistry of ATPases. (1990) (38)
- Immunocytochemistry and Laser Capture Microdissection for Real-time Quantitative PCR Identify Hindbrain Neurons Activated by Interaction Between Leptin and Cholecystokinin (2008) (36)
- Fine structure, functional organization and supportive role of neuroglia in Nereis. (1971) (35)
- Endocrine regulation of food intake and body weight. (1996) (33)
- The infracerebral gland — a possible neuroendocrine complex in Nereis (1968) (33)
- Immunocytochemical identification of cells containing insulin, glucagon, somatostatin, and pancreatic polypetide in the islets of langerhans of the guinea pig pancreas with light and electron microscopy (1984) (32)
- Insulin binding in the hypothalamus of lean and genetically obese Zucker rats (1989) (32)
- Calibration of [14C]plastic standards for quantitative autoradiography of [125I]labeled ligands with Amersham Hyperfilm β-max (1989) (28)
- Inheritance of diabetes mellitus in Keeshond dogs. (1988) (28)
- The Coelomocytes of Nereid Polychaetes (1974) (27)
- Immunocytochemical Study of the Pancreatic Islets of the Pacific Salmon,Oncorhynchus kisutch (1986) (25)
- Effects of ginkgolide B, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic BB rat. (1991) (25)
- Evidence for separate receptors for insulin and insulin-like growth factor-I in choroid plexus of rat brain by quantitative autoradiography. (1990) (25)
- Insulin binding to individual rat skeletal muscles. (1990) (24)
- Localization and Characterization of Binding Sites with High Affinity for [3H]Ouabain in Cerebral Cortex of Rabbit Brain Using Quantitative Autoradiography (1989) (24)
- Leptin and the brain: then and now. (2013) (24)
- Selection of oligonucleotide probes for detection of mRNA isoforms. (1993) (24)
- Correlative light and electron microscopic immunocytochemistry on the same section with colloidal gold. (1987) (23)
- The Online Journal of Histochemistry and Cytochemistry (1998) (23)
- Apolipoprotein E Mediates the Retention of High-Density Lipoproteins by Mouse Carotid Arteries and Cultured Arterial Smooth Muscle Cell Extracellular Matrices (2002) (22)
- Metabolic, gastrointestinal, and CNS neuropeptide effects of brain leptin administration in the rat. (1999) (22)
- The canine sympathetic neuropeptide galanin: a neurotransmitter in pancreas, a neuromodulator in liver. (1999) (22)
- Reduction of insulin binding in the arcuate nucleus of the rat hypothalamus after 6-hydroxydopamine treatment (1989) (22)
- Workshop on in situ hybridization: what you need to know to get it to work. (1993) (20)
- [3H]-ouabain binding sites in rat brain: distribution and properties assessed by quantitative autoradiography. (1992) (20)
- The fine structure of neuroglia in the central nervous system of nereid polychaetes (2004) (18)
- Calibration of 14C-plastic standards for quantitative autoradiography with 33P. (1994) (18)
- Peptide-carrier interaction: induction of liposome fusion and aggregation by insulin. (1986) (18)
- Evidence that galanin is a parasympathetic, rather than a sympathetic, neurotransmitter in the baboon pancreas (1996) (18)
- Localization of 3H-prazosin binding sites in the supraoptic and paraventricular nuclei of the human hypothalamus. (1990) (17)
- Neurosecretion and the Endocrinology of Nereid Polychaetes (1976) (17)
- Standardization of tritium-sensitive film for quantitative autoradiography. (1989) (17)
- Interleukin-1β regulation of islet and thyroid autoimmunity in the BB rat (1991) (16)
- Immunocytochemical detection of B cells in the guinea pig pancreas using guinea pig antiserum to porcine insulin. (1981) (16)
- Functional classification of cell types in the growth hormone- and prolactin-secreting rat MtTW mammosomatotropic tumor with ultrastructural immunocytochemistry. (1980) (16)
- Gamma-endorphin-like peptides in pituitary tissue: Evidence for their existence in vivo (1982) (16)
- Immunocytochemical localization of Na+, K+-ATPase in the rat kidney (2004) (14)
- Thrittene, Homologous with Somatostatin-28(1-13), Is a Novel Peptide in Mammalian Gut and Circulation. (2002) (14)
- Studies on the infracerebral gland of the polychaete annelid, Nereis limnicola, in relation to reproduction, salinity, and regeneration. (1970) (14)
- Galanin is localized in sympathetic neurons of the dog liver. (1997) (13)
- Fixation and Tissue Processing in Immunohistochemistry (2014) (13)
- Obesity is associated with hypothalamic injury in rodents and humans (The Journal of Clinical Investigation (2012) 122, 1, (153-162) DOI (2012) (13)
- Single-minded view of melanocortin signaling in energy homeostasis. (2006) (12)
- Electron microscopic immunoperoxidase staining of insulin using 4-chloro-1-naphthol after osmium fixation. (1982) (12)
- Weight loss in rats following intraventricular transplants of pancreatic islets. (1994) (12)
- Localization of Na, K-ATPase isoforms in the hypothalamus of the rat. (1995) (11)
- Effect of paraformaldehyde fixation on localization and characterization of insulin‐like growth factor‐I (IGF‐I) receptors in the rat brain (1991) (11)
- Heterogeneity of the MtTW15 mammosomatotropic tumor. II. Characterization of parenchymal cells by superimposition immunocytochemistry and electron microscopy (1980) (10)
- Regulation of Food Intake and Body Weight (1997) (10)
- Further observations on the fine structure and development of the infracerebral complex (“infracerebral gland”) of Nereis limnicola (Annelida, Polychaeta) (2004) (10)
- Experimental studies on the endocrinology and reproductive biology of the viviparous polychaete annelid, Nereis limnicola Johnson. (1970) (10)
- The fine structure of polychaete septate junctions (1976) (9)
- Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation. (2002) (9)
- Fos expression in rat celiac ganglion: an index of the activation of postganglionic sympathetic nerves. (2001) (9)
- Electron microscopic study on the gill bars of amphioxus (Brachiostoma californiense) with special reference to Neurociliary control (1976) (9)
- Major species variation in the expression of galanin messenger ribonucleic acid in mammalian celiac ganglion. (1994) (8)
- A possible neuroendocrine system in polynoid polychaetes (1971) (8)
- Immuno-laser capture microdissection of rat brain neurons for real time quantitative PCR. (2010) (8)
- Insulin in the Central Nervous System: A Regulator of Appetite and Body Weight (1987) (8)
- Physiological and morphological changes in islet B cells following treatment of the guinea pig with alloxan. (1986) (7)
- Protection from BB rat diabetes by the platelet-activating factor inhibitor BN50730. (1993) (6)
- Improving the State of the Science of Immunohistochemistry (2014) (6)
- Insulin-Like Growth Factor Receptors in the Brain (1987) (6)
- Cytotoxic effects of alloxan treatment in vitro on monolayer cultures of neonatal rat pancreas. (1983) (6)
- Insulin-Like Growth Factors as Regulatory Peptides in the Adult Rat Brain (1989) (5)
- Food intake and estradiol effects on insulin binding in brain and liver (1993) (5)
- Insulin as a regulatory peptide in the CNS (1988) (4)
- Identification of Neuropeptide Receptors (1987) (4)
- Enzyme- Based Fluorescence Amplification for Immunohistochemistry and In Situ Hybridization (2004) (4)
- Characterization of insulin-like growth factor-II binding sites in the rat brain by quantitative autoradiography: Evidence for an IGF-II binding protein (1990) (3)
- Leptin Interaction with Brain Orexigenic and Anorexigenic Pathways (2015) (3)
- Localization and measurement of neurotransmitter receptors in rat and human brain by quantitative autoradiography. (1989) (1)
- Third Seattle Islet Symposium : Recent advances in signaling mechanisms common to the nervous system and islets (1999) (1)
- Comments on the relation among GAD–65, IA-2 antibodies and body adiposity (2000) (1)
- Interleukin-1 beta regulation of islet and thyroid autoimmunity in the BB rat. (1991) (1)
- Rapid Publication Specificity of Leptin Action on Elevated Blood Glucose Levels and Hypothalamic Neuropeptide Y Gene Expression in ob/ob Mice (1996) (1)
- Free Color Pages (2001) (1)
- Publish and Perish (2007) (1)
- Chronic CNS Oxytocin Signaling Preferentially Induces Fat Loss in High Fat 3 Diet-Fed Rats by Enhancing Satiety Responses and Increasing Lipid Utilization 4 5 Abbreviated title : Oxytocin Reduces Body Adiposity in High Fat Diet-Fed Rats 6 7 (2016) (0)
- Histochemical Insights into Pancreatic Islet Biology (2015) (0)
- Insulin and insulin-like growth fadors in the CN$ (1988) (0)
- P-2: Insulin and food intake increase neuronal phosphotyrosine levels in the arcuate nucleus of the rat hypothalamus (2009) (0)
- Mechanisms underlying anorexia induced by Leydig cell tumors (1996) (0)
- Image Analysis for Quantitative Autoradiography of Receptors. (1990) (0)
- Contributions of histochemistry to the neuroendocrinology of obesity and body weight regulation (2004) (0)
- Neurotoxic lesioning of oxytocin-sensing hindbrain neurons attenuates the satiety response to CCK-8 (2009) (0)
- 147 LOCALIZATION OF INSULIN RECEPTOR SUBSTRATE 2 IN BRAIN AREAS IMPORTANT FOR ENERGY HOMEOSTASIS. (2006) (0)
- Fos expression in rat celiac ganglion (2001) (0)
- OB protein inhibits hypothalamic neuropeptide y gene expression in ob/ob, but not db/db, mice (1996) (0)
- P2-09 Immunocytochemical detection of phosphatidylinositol 3-kinase (PI3K) activation by insulin and leptin (2002) (0)
- Comments on the NIH Enhanced Public Access Policy (2005) (0)
- The role of intestinal glucagon-like peptide 1 in satiety. (2007) (0)
- More Changes (1997) (0)
- WITHDRAWN: Leptin enhances and fasting inhibits the anorexic response to Exendin-4 in the rat (2006) (0)
- Neuronal targets of leptin and insulin in the brain (2009) (0)
- Galanin is localized in sympathetic neurons of the dog liver. (1997) (0)
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