Derek G. Smyth
#135,021
Most Influential Person Now
Derek G. Smyth's AcademicInfluence.com Rankings
Derek G. Smythchemistry Degrees
Chemistry
#3264
World Rank
#4267
Historical Rank
Organic Chemistry
#517
World Rank
#597
Historical Rank

Download Badge
Chemistry
Derek G. Smyth's Degrees
- PhD Chemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Derek G. Smyth Influential?
(Suggest an Edit or Addition)Derek G. Smyth's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mechanism of C-terminal amide formation by pituitary enzymes (1982) (557)
- C fragment of lipotropin has a high affinity for brain opiate receptors (1976) (467)
- The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations. (1963) (408)
- Reactions of N-ethylmaleimide with peptides and amino acids. (1964) (312)
- The use of cyanate for the determination of NH2-terminal residues in proteins. (1963) (291)
- Endorphins are stored in biologically active and inactive forms: isolation of α-N-acetyl peptides (1979) (243)
- Some Reactions of N-Ethylmaleimide1 (1960) (230)
- β-Endorphin is processed differently in specific regions of rat pituitary and brain (1982) (162)
- Distribution of active and inactive forms of endorphins in rat pituitary and brain. (1979) (160)
- Biosynthetic origin and receptor conformation of methionine enkephalin (1976) (155)
- The determination of glucosamine and galactosamine. (1970) (154)
- Lipotropin: precursor to two biologically active peptides. (1976) (146)
- Influence of N-terminal acetylation and C-terminal proteolysis on the analgesic activity of beta-endorphin. (1980) (140)
- Induction of excessive grooming in the rat by fragments of lipotropin (1976) (140)
- Vasopressin coexists in half of the corticotropin-releasing factor axons present in the external zone of the median eminence in normal rats. (1987) (128)
- Distribution of beta-endorphin-related peptides in rat pituitary and brain. (1982) (126)
- [24] Techniques in enzymic hydrolysis (1967) (123)
- Dependence creating properties of lipotropin C-fragment (beta-endorphin): evidence for its internal control of behavior. (1979) (105)
- Selective processing of β-endorphin in regions of porcine pituitary (1980) (103)
- Induction of tolerance to the analgesic action of lipotropin C-Fragment (1976) (102)
- C‐FRAGMENT OF LIPOTROPIN—AN ENDOGENOUS POTENT ANALGESIC PEPTIDE (1977) (101)
- Peptide amidation. (1991) (98)
- On the sequence of residues 11 to 18 in bovine pancreatic ribonuclease. (1962) (92)
- beta-Endorphin and related peptides in pituitary, brain, pancreas and antrum. (1983) (84)
- γ Endorphin, α endorphin and Met-enkephalin are formed extracellularly from lipotropin C fragment (1977) (81)
- A new glycopeptide in pig, ox and sheep pituitary. (1979) (80)
- Biosynthesis of the C-terminal amide in peptide hormones (1987) (80)
- Endopeptidases and prohormone processing (1990) (76)
- A novel peptide, pyroglutamylglutamylproline amide, in the rabbit prostate complex, structurally related to thyrotrophin-releasing hormone. (1989) (74)
- The glycopeptide moiety of vasopressin-neurophysin precursor is neurohypophysial prolactin releasing factor. (1988) (69)
- Substrate specificity of an amidating enzyme in porcine pituitary. (1983) (65)
- Proinsulin: a proposed three-dimensional structure. (1975) (60)
- Comparison of the analgesic properties of lipotropin C-fragment and stabilized enkephalins in the rat. (1977) (57)
- Acetylation of amino and tyrosine hydroxyl groups. Preparation of inhibitors of oxytocin with no intrinsic activity on the isolated uterus. (1967) (53)
- Isolation and identification of two neutral thyrotropin releasing hormone-like peptides, pyroglutamylphenylalanineproline amide and pyroglutamylglutamineproline amide, from human seminal fluid. (1992) (52)
- Glycyl glutamine, an inhibitory neuropeptide derived from β-endorphin (1983) (50)
- Immunocytochemical localization of ß-endorphin (lipotropin c-fragment) in the developing rat spinal cord and hypothalamus (1982) (47)
- 4-Phenyl-3-butenoic acid, an in vivo inhibitor of peptidylglycine hydroxylase (peptide amidating enzyme). (1990) (46)
- Isolation of the C-fragment and C'-fragment of lipotropin from pig pituitary and C-fragment from brain. (1978) (46)
- The NH2-terminus of C-fragment is resistant to the action of aminopeptidases. (1977) (45)
- Enzyme‐catalysed peptide amidation (1987) (45)
- The amidating enzyme in pituitary will accept a peptide with C-terminal D-alanine as substrate. (1983) (43)
- The oligosaccharide units of rabbit immunoglobulin G. Multiple carbohydrate attachment sites. (1972) (43)
- Evidence for the Neurotrophic Regulation of Collagen‐Tailed Acetylcholinesterase in Immature Skeletal Muscle by β‐Endorphin (1984) (42)
- Analgesic activity of lipotropin C fragment depends on carboxyl terminal tetrapeptide (1977) (40)
- Specific cleavage of lipotropin C-fragment by endopeptidases; evidence for a preferred conformation. (1977) (37)
- The amino acid sequence of the C-peptide of human proinsulin. (1971) (37)
- Catalysis of Slow C‐Terminal Processing Reactions by Carboxypeptidase H (1989) (35)
- The TRH‐related peptide pyroglutamylglutamylprolinamide is present in human semen (1989) (35)
- Distribution of pyroglutamylpeptide amides related to thyrotrophin-releasing hormone in the central nervous system and periphery of the rat. (1990) (32)
- The thyrotrophin-releasing hormone (TRH)-like peptides in rat prostate are not formed by expression of the TRH gene but are suppressed by thyroid hormone. (1992) (29)
- The oligosaccharide units of rabbit immunoglobulin G. Asymmetric attachment of C2-oligosaccharide. (1972) (29)
- The C-fragment of lipotropin - a potent analgesic [proceedings]. (1976) (28)
- Specific processing of the thyrotropin-releasing prohormone in rat brain and spinal cord. (1987) (28)
- The use of 3-bromopropionic acid for the determination of protein thiol groups. (1973) (27)
- Unequivocal assignments of NH proton magnetic resonance bands in oxytocin using 2H‐ and 15N‐substituted molecules (1974) (26)
- 60 YEARS OF POMC: Lipotropin and beta-endorphin: a perspective. (2016) (24)
- β-Endorphin processing in pituitary and brain is sensitive to haloperidol stimulation (1985) (24)
- β‐Endorphin and ACTH related peptides in primary cultures of rat anterior pituitary cells: evidence for different intracellular pools (1985) (24)
- Chromatography of peptides related to β-endorphin (1984) (23)
- Regulation of bioactive β‐endorphin processing in rat pars intermedia (1984) (23)
- Susceptibility of neuroactive peptides to aminopeptidase digestion is related to molecular size. (1979) (22)
- The processing of β-endorphin and α-melanotrophin in the pars intermedia of Xenopus laevis is influenced by background adaptation (1992) (22)
- Metabolism of the analgesic peptide lipotropin C‐Fragment in rat striatal slices (1977) (21)
- The peptide hormones: molecular and cellular aspects (1975) (20)
- Continuous infusion of propofol in dystrophia myotonica (1989) (19)
- The synthesis of tritiovaline and its incorporation into rat-visceral proteins. (1958) (19)
- Purification of a cysteine endopeptidase which is secreted with bioactive peptides from the epidermal glands of Xenopus laevis. (1991) (18)
- Some analytical problems involved in determining the structure of proteins and peptides. A review (1964) (18)
- Lipotropin C-fragment has a COOH-terminal sequence with high intrinsic resistance to the action of exopeptidases. (1977) (18)
- Carbamylation of amino and tyrosine hydroxyl groups. Preparation of an inhibitor of oxytocin with no intrinsic activity on the isolated uterus. (1967) (18)
- Prohormones of beta-melanotropin (beta-melanocyte-stimulating hormone, beta-MSH) and corticotropin (adrenocorticotropic hormone, ACTH): structure and activation. (1976) (18)
- Processing of the thyrotropin releasing hormone (TRH) precursor in Xenopus skin and bovine hypothalamus: evidence for the existence of extended forms of TRH (1986) (17)
- Thyrotrophin-releasing hormone-related polypeptides in rabbit prostate and semen are different from those in rabbit hypothalamus. (1989) (17)
- Chronic stimulation of anterior pituitary cell cultures with CRF leads to the secretion of lipotropin. (1986) (16)
- Hallucinations after propofol (1988) (16)
- α, N-acetyl derivatives of β-endorphin in rat pituitary: Chromatographic evidence for processed forms of β-endorphin in pancreas and brain (1982) (16)
- The TRH‐like peptides in rabbit testis are different from the TRH‐like peptide in the prostate (1996) (15)
- Endorphins are stored in biologically active and inactive forms: isolation of alpha-N-acetyl peptides. (1979) (15)
- Proton magnetic resonance studies on [methionine]-enkephalin and beta-endorphin in aqueous solution. (1979) (14)
- Bovine proinsulin: amino acid sequence of the C-peptide isolated from pancreas. (1971) (14)
- The thyrotropin-releasing hormone-like peptides pGlu-Phe-Pro amide and pGlu-Glu-Pro amide increase plasma triiodothyronine levels in the mouse; the activity is sensitive to testosterone. (1998) (13)
- Preparation and characterisation of a specific antiserum to the C‐Fragment of lipotropin (1977) (12)
- Beta-endorphin is present in active and inactive forms in rat gastric antrum. (1986) (12)
- Some techniques in the assay of tritium. (1956) (12)
- Selective processing of beta-endorphin in regions of porcine pituitary. (1980) (12)
- Studies on the asymmetrically attached oligosaccharide of rabbit immunoglobulin-G. I. Biosynthesis and stability of the C2-oligosaccharide. (1970) (12)
- Preparation of human C-peptide. (1971) (12)
- Substrate recognition by UDP-N-acetyl-α-d-galactosamine: polypeptide N-acetyl-α-d-galactosaminyltransferase. Effects of chain length and disulphide bonding of synthetic peptide substrates (1988) (12)
- Analgesia produced in cats by the C-fragment of lipotropin and by a synthetic pentapeptide [proceedings]. (1977) (11)
- The C-terminal dipeptide of β-endorphin: A neuropeptide with inhibitory activity (1983) (11)
- Antigenicity of the β-Chain of Human Hæmoglobin (1964) (11)
- Sequential formation of beta-endorphin-related peptides in porcine pituitary. (1988) (11)
- Isolation and identification of N-terminally extended forms of 5-oxoprolylglutamylprolinamide (Glp-Glu-Pro-NH2), a thyrotropin-releasing-hormone (TRH)-like peptide present in human semen. (1993) (11)
- Peptide amidation: evidence for multiple molecular forms of the amidating enzyme. (1988) (10)
- Beta-endorphin-related peptides in the pituitary gland: isolation, identification and distribution. (1981) (10)
- Glycyl glutamine, an inhibitory neuropeptide derived from beta-endorphin. (1983) (10)
- Studies on the Bohr Effect of Sheep Hemoglobin (1961) (10)
- Studies on the asymmetrically attached oligosaccharide of rabbit immunoglobulin-G. II. On the biological function of the C2-oligosaccharide. (1970) (10)
- Characterization of neutral TRH-like peptides in mammary gland, mammary tumors and milk. (2000) (10)
- Carbamylation of Oxytocin and Arginine-Vasopressin (1963) (9)
- Detection of TRH extended peptides in rat hypothalamus using an antibody raised to pGluHisProGlyLys (1986) (9)
- Use of 125I-Tyr27 β-Endorphin for the Study of β-Endorphin Binding Sites in Rat Cortex (1986) (9)
- Influence of dopaminergic agents on beta-endorphin processing in rat pars intermedia. (1984) (9)
- Characterization of a proteolytic enzyme in the skin secretions of Xenopus laevis. (1988) (9)
- Guinea pig proinsulin. Primary structure of the C-peptide isolated from pancreas. (1975) (8)
- Isolation of beta-endorphin-related peptides from ox pituitary. (1980) (8)
- Identification of the TRH-like peptides pGlu–Glu–Pro amide and pGlu–Phe–Pro amide in rat thyroid: regulation by thyroid status (1999) (8)
- ISOLATION AND IDENTIFICATION OF TWO NEW PEPTIDES RELATED TO β-ENDORPHIN (1981) (8)
- Molecular cloning in the marmoset shows that semenogelin is not the precursor of the TRH-like peptide pGlu-Glu-Pro amide. (1998) (8)
- Proteolysis of Lipotropin C-Fragment Takes Place Extracellularly to Form γ-Endorphin and [Methionine]Enkephalin (1977) (7)
- Synthesis and high-performance liquid chromatographic purification of tritiated thyrotrophin-releasing hormone-like peptides. (1994) (7)
- Sequential processing reactions in the formation of hormone amides. (1987) (7)
- Studies on limited proteolysis and degradation of lipotropin C-fragment [proceedings]. (1977) (7)
- Exaggerated physiological responses to propofol in myotonic dystrophy. (1990) (7)
- Pyroglutamylpeptide amides in rat central nervous system: possible new class of neurotransmitter. (1990) (6)
- The effect of acylation on the molecular size of insulin. (1972) (6)
- β-Endorphin in Brain (1982) (6)
- Effects of vasopressin-glycine and vasopressin-glycine-lysine-arginine on renal function in the rat. (1986) (6)
- Biogenesis and metabolism of opiate active peptides (1978) (5)
- Enzyme-catalysed peptide amidation. Isolation of a stable intermediate formed by reaction of the amidating enzyme with an imino acid. (1987) (5)
- Isolation and characterization of endogenous [α]-n-acyl derivatives of the C and C′ of lph (1979) (5)
- gamma endorphin, alpha endorphin and Met-enkephalin are formed extracellularly from lipotropin C fragment. (1977) (5)
- Quantitative blocking of amino groups in acid solution by carbamylation (1966) (5)
- The amino acid sequence of guinea pig C-peptide (1974) (5)
- On the molecular mechanism of oxytocin action. (1970) (5)
- β-endrophin: modulation of acute tolerance and antagonism by endogenous brain systems (1978) (5)
- Isolation of glycylglutamine, the C-terminal dipeptide of the β-endorphin corticotropin prohormone (1982) (4)
- Conformational properties of the opiate peptide C-fragment, and related peptides from lipotropin [proceedings]. (1977) (4)
- Processing reactions in the later stages of hormone activation. (1988) (4)
- PRIMARY STRUCTURE AND SPECIFICITY IN ENDOGENOUS OPIOID PEPTIDES (1980) (4)
- Synthesis of tritium labelled TRH-like peptides using asymmetric anhydride coupling (1991) (3)
- The common prohormone of corticotropin and the opiate peptide lipotropin C-fragment (beta-endorphin). (1978) (3)
- Acylation reactions with cyclic imides. (1968) (3)
- Lipotropin and beta-endorphin : a perspective (2016) (3)
- Constructing semisynthetic polypeptides (1975) (3)
- The C-terminal dipeptide of beta-endorphin: a neuropeptide with inhibitory activity. (1983) (3)
- Olefinic additions with asymmetric reactants. Part III. The resolution and addition reactions of 3-ethylhept-3-en-2-ol. A partial asymmetric synthesis effected by hydrogenation (1955) (3)
- Chromatography of peptides related to beta-endorphin. (1984) (3)
- Molecular Changes in Exchange Labelling with Tritium (1958) (3)
- beta-Endorphin: modulation of acute tolerance and antagonism by endogenous brain systems. (1978) (3)
- β-ENDORPHIN IN THE BRAIN AND PITUITARY; EVIDENCE FOR TWO SPECIFIC PROCESSING PATTERNS (1981) (3)
- Preparation and properties of lipotropin C‐Fragment with anionic substituents attached to the lysine residues (1977) (3)
- beta-Endorphin in brain. (1982) (3)
- Fluorescent inhibitors of peptidylglycine hydroxylase (1991) (2)
- Amidation of Synthetic Peptides by Pituitary Enzyme: Specificity and Mechanism of the Reaction (1983) (2)
- The processing of beta-endorphin and alpha-melanotrophin in the pars intermedia of Xenopus laevis is influenced by background adaptation. (1992) (2)
- Use of 125I-Tyr27 beta-endorphin for the study of beta-endorphin binding sites in rat cortex. (1986) (2)
- alpha, N-acetyl derivatives of beta-endorphin in rat pituitary: chromatographic evidence for processed forms of beta-endorphin in pancreas and brain. (1982) (2)
- [47] Use of papain, pepsin, and subtilisin in sequence determination (1967) (2)
- Biologically active macromolecular forms of oxytocin. [8-Lysine]oxytocin as a suitable ligand. (1977) (2)
- Interactions of peptides derived from the C-fragment of beta-lipotropin with brain opiate receptors [proceedings]. (1976) (2)
- Regulation of bioactive beta-endorphin processing in rat pars intermedia. (1984) (2)
- ANTIGENICITY OF THE BETA-CHAIN OF HUMAN HAEMOGLOBIN. (1964) (1)
- Methods used in the study of TRH-like peptides in rat prostate. (1991) (1)
- C‐Terminally Extended Forms of Thyrotropin‐Releasing Hormone (TRH) in Rat Brain and Spinal Cord (1989) (1)
- Effects of C-fragment on brain stem neurones in the cat [proceedings]. (1977) (1)
- Protirelin (thyrotropin-releasing hormone) in thyroid gland: possible involvement in regulation of thyroid status. (1999) (1)
- MECHANISMS FOR ACTIVATION AND INACTIVATION OF ENDORPHINS (1981) (1)
- The quest for a latent action insulin. (1973) (1)
- [125I] Tyr27 β-endorphin: A radio-iodinated derivative of β-endorphin for the study of opiate receptors (1984) (1)
- CHEMICAL REACTIONS OF N-ETHYLMALEIMIDE (1966) (1)
- Contents (2010) (0)
- Subject Index Vol. 43, 1986 (1986) (0)
- A study of the substrate specificity of carboxypeptidase H (1988) (0)
- Differential Regulation of ACTH and β-Endorphin by Controlled Processing (1986) (0)
- SPECIFIC PROCESSING OF ENDORPHINS IN RAT BRAIN (1980) (0)
- Extended Peptides in Rat an Antibody Raised to (2005) (0)
- Inhibitory actions of diketopiperazines within the thyroid gland, and their system-wide presence (2019) (0)
- Biosynthesis of peptide neurotransmitters: studies on the formation of peptide amides. (1988) (0)
- Selective processing of the 31000-molecular-weight adrenocorticotropin prohormone of endorphin: activation and inactivation mechanisms (1980) (0)
- Resolution of 3 ethylhept 3 En 2 Ol and the stereochemistry of some addition reactions with the (2)-, (-)-, and (+)- alcohols (1954) (0)
- Detection of TRH Hypothalamus Using pGluHis ProGlyLys (1986) (0)
- The biosynthesis of a tritium-labelled antibody. (1958) (0)
- Biosynthesis and Targeting of β-Endorphin (1986) (0)
- Proteolysis of lipotropin C-fragment takes place extracellularly to form gamma-endorphin and [methionine]enkephalin [proceedings]. (1977) (0)
- Stanford Moore 1913–1982 (1983) (0)
- The relationship between the structure and biological activity of some peptides and proteins (excluding enzymes) (1969) (0)
- [125I] Tyr27 beta-endorphin: a radio-iodinated derivative of beta-endorphin for the study of opiate receptors. (1984) (0)
- The Importance of Defined Tracers in RIA (1986) (0)
- PREPARATION OF SUBSTRATE INHIBITORS OF THE AMIDATING ENZYME IN PORCINE PITUITARY (1987) (0)
- Exaggerates physiological responses to propofol in myotonic dystrophy. Author's reply (1990) (0)
- Effects ofC-fragment onbrain stem neurones inthecat (1977) (0)
- Chemical modifications of proteins : by A. N. Glazer, R. J. Delange and D. S. Sigman North-Holland Publishing Company; Amsterdam, New York, 1975 iv + 205 pages. Dfl. 28.00, $ 11.75 (paper) (1977) (0)
- Regulation of processing in multi-functional prohormones: a new hypothesis. (1985) (0)
- Prohormone processing reactions: discrete stages in the formation of beta-endorphin related peptides. (1986) (0)
- Substrate recognition by UDP-N-acetyl-alpha-D-galactosamine: polypeptide n-acetyl-alpha-D-galactosaminyltransferase. Effects of chain length and disulphide bonding of synthetic peptide substrates. (1988) (0)
- The use of cyanate for the determination of NH 2 -terminal residues in N-acylated proteins. (1973) (0)
- Processing of thyrotropin-releasing-hormone-related peptides in rabbit hypothalamus and prostate (1988) (0)
- Subject Index Vol. 44, 1986 (1986) (0)
- Radiolabelling in studies of peptide hormones (1988) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Derek G. Smyth?
Derek G. Smyth is affiliated with the following schools: