David Herman Maclennan
#99,911
Most Influential Person Now
David Herman Maclennan's AcademicInfluence.com Rankings
David Herman Maclennanbiology Degrees
Biology
#4934
World Rank
#7286
Historical Rank
Cell Biology
#130
World Rank
#135
Historical Rank
Molecular Biology
#410
World Rank
#418
Historical Rank
Genetics
#429
World Rank
#495
Historical Rank
Download Badge
Biology
David Herman Maclennan's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Molecular Biology Stanford University
Similar Degrees You Can Earn
Why Is David Herman Maclennan Influential?
(Suggest an Edit or Addition)David Herman Maclennan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. (1991) (1454)
- Calcium: Phospholamban: a crucial regulator of cardiac contractility (2003) (972)
- Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps. (1992) (655)
- Two Ca2+ ATPase genes: Homologies and mechanistic implications of deduced amino acid sequences (1986) (652)
- Purification and properties of an adenosine triphosphatase from sarcoplasmic reticulum. (1970) (628)
- Dilated Cardiomyopathy and Heart Failure Caused by a Mutation in Phospholamban (2003) (603)
- Molecular cloning of cDNA encoding human and rabbit forms of the Ca2+ release channel (ryanodine receptor) of skeletal muscle sarcoplasmic reticulum. (1990) (557)
- Molecular cloning of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit cardiac muscle sarcoplasmic reticulum. (1990) (551)
- Calreticulin Is Essential for Cardiac Development (1999) (523)
- Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia (1990) (509)
- Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium. (1993) (507)
- Location of high affinity Ca2 +-binding sites within the predicted transmembrahe domain of the sarco-plasmic reticulum Ca2+-ATPase (1989) (501)
- Isolation of a calcium-sequestering protein from sarcoplasmic reticulum. (1971) (478)
- The Mechanism of Ca2+ Transport by Sarco(Endo)plasmic Reticulum Ca2+-ATPases* (1997) (462)
- Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human. (2003) (438)
- Molecular cloning of the high affinity calcium-binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum. (1989) (384)
- Staining of the Ca2+-binding proteins, calsequestrin, calmodulin, troponin C, and S-100, with the cationic carbocyanine dye "Stains-all". (1983) (380)
- cDNA cloning, functional expression, and mRNA tissue distribution of a third organellar Ca2+ pump. (1989) (364)
- Isolation of a high affinity calcium-binding protein from sarcoplasmic reticulum. (1974) (341)
- Adult forms of the Ca2+ATPase of sarcoplasmic reticulum. Expression in developing skeletal muscle. (1987) (332)
- A mutation in the human ryanodine receptor gene associated with central core disease (1993) (326)
- Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene. (1988) (321)
- A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy (2006) (317)
- A substitution of cysteine for arginine 614 in the ryanodine receptor is potentially causative of human malignant hyperthermia. (1991) (308)
- Regulation of myocardial Ca2+-ATPase and phospholamban mRNA expression in response to pressure overload and thyroid hormone. (1989) (291)
- Amino-acid sequence of a Ca2++Mg2+-dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence (1985) (290)
- Phospholamban Inhibitory Function Is Activated by Depolymerization* (1997) (278)
- Mutation of aspartic acid-351, lysine-352, and lysine-515 alters the Ca2+ transport activity of the Ca2+-ATPase expressed in COS-1 cells. (1988) (264)
- Caffeine and Halothane Sensitivity of Intracellular Ca2+ Release Is Altered by 15 Calcium Release Channel (Ryanodine Receptor) Mutations Associated with Malignant Hyperthermia and/or Central Core Disease* (1997) (249)
- Studies on the electron transfer system. LXVII. Polyacrylamide gel electrophoresis of the mitochondrial electron transfer complexes. (1966) (242)
- Sarcolipin Regulates the Activity of SERCA1, the Fast-twitch Skeletal Muscle Sarcoplasmic Reticulum Ca2+-ATPase* (1998) (241)
- A mutation in the transmembrane/luminal domain of the ryanodine receptor is associated with abnormal Ca2+ release channel function and severe central core disease. (1999) (234)
- Ca2+ signalling and muscle disease. (2000) (232)
- Membrane formation by the adenosine triphosphatase of sarcoplasmic reticulum. (1971) (223)
- Isolation and properties of an iron-protein from the (reduced coenzyme Q)-cytochrome C reductase complex of the respiratory chain (1964) (221)
- Effect of thyroid hormone on the expression of mRNA encoding sarcoplasmic reticulum proteins. (1991) (216)
- Measurement of Resting Cytosolic Ca2+ Concentrations and Ca2+ Store Size in HEK-293 Cells Transfected with Malignant Hyperthermia or Central Core Disease Mutant Ca2+ Release Channels* (1999) (209)
- Calcium transport in sarcoplasmic reticulum. (1975) (205)
- Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development. (1992) (200)
- Studies on the mitochondrial adenosine triphosphatase system. IV. Purification and characterization of the oligomycin sensitivity conferring protein. (1968) (198)
- Amino acid sequence of rabbit fast-twitch skeletal muscle calsequestrin deduced from cDNA and peptide sequencing. (1987) (195)
- An autosomal dominant congenital myopathy with cores and rods is associated with a neomutation in the RYR1 gene encoding the skeletal muscle ryanodine receptor. (2000) (192)
- Modeling of the inhibitory interaction of phospholamban with the Ca2+ ATPase (2003) (192)
- Molecular cloning of the mammalian smooth muscle sarco(endo)plasmic reticulum Ca2+-ATPase. (1989) (178)
- Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease. (1997) (162)
- Isolation of Sarcoplasmic Reticulum Proteins (1973) (161)
- The Regulation of SERCA‐Type Pumps by Phospholamban and Sarcolipin (2003) (159)
- Sarcolipin regulates sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) by binding to transmembrane helices alone or in association with phospholamban (2003) (157)
- The structural organization of the human skeletal muscle ryanodine receptor (RYR1) gene. (1996) (156)
- Purification and characterization of calsequestrin from canine cardiac sarcoplasmic reticulum and identification of the 53,000 dalton glycoprotein. (1983) (154)
- Surface particles of sarcoplasmic reticulum membranes. Structural features of the adenosine triphosphatase. (1974) (151)
- Amino acids Glu2 to Ile18 in the cytoplasmic domain of phospholamban are essential for functional association with the Ca(2+)-ATPase of sarcoplasmic reticulum. (1994) (149)
- The Mechanism of Ca 2 1 Transport by Sarco ( Endo ) plasmic Reticulum Ca 2 1-ATPases * (1997) (148)
- Cosegregation of porcine malignant hyperthermia and a probable causal mutation in the skeletal muscle ryanodine receptor gene in backcross families. (1991) (147)
- Topology of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum (RyR1) (2002) (144)
- Characterization of rabbit cardiac sarco(endo)plasmic reticulum Ca2(+)-ATPase gene. (1990) (141)
- 'Compartmentation' of acids in plant tissues. (1963) (141)
- Identification of Ser38 as the site in cardiac sarcoplasmic reticulum Ca(2+)-ATPase that is phosphorylated by Ca2+/calmodulin-dependent protein kinase. (1994) (136)
- Cardiovascular proteomics: tools to develop novel biomarkers and potential applications. (2006) (134)
- Superinhibition of Sarcoplasmic Reticulum Function by Phospholamban Induces Cardiac Contractile Failure* (2001) (134)
- The Vmax of the Ca2+-ATPase of Cardiac Sarcoplasmic Reticulum (SERCA2a) Is Not Altered by Ca2+/Calmodulin-dependent Phosphorylation or by Interaction with Phospholamban* (1996) (134)
- Proteome Dynamics during C2C12 Myoblast Differentiation*S (2005) (132)
- Amino acids Lys-Asp-Asp-Lys-Pro-Val402 in the Ca(2+)-ATPase of cardiac sarcoplasmic reticulum are critical for functional association with phospholamban. (1994) (132)
- Phospholamban Regulates the Ca2+-ATPase through Intramembrane Interactions* (1996) (131)
- Polymorphisms and deduced amino acid substitutions in the coding sequence of the ryanodine receptor (RYR1) gene in individuals with malignant hyperthermia. (1992) (129)
- Identification of regions in the Ca(2+)-ATPase of sarcoplasmic reticulum that affect functional association with phospholamban. (1993) (128)
- Functional consequences of glutamate, aspartate, glutamine, and asparagine mutations in the stalk sector of the Ca2+-ATPase of sarcoplasmic reticulum. (1989) (126)
- Functional consequences of proline mutations in the cytoplasmic and transmembrane sectors of the Ca2(+)-ATPase of sarcoplasmic reticulum. (1989) (126)
- Formation of membranes by repeating units. (1967) (124)
- Quercetin interaction with the (Ca2+ + Mg2+)-ATPase of sarcoplasmic reticulum. (1981) (123)
- Identification of calmodulin-, Ca(2+)-, and ruthenium red-binding domains in the Ca2+ release channel (ryanodine receptor) of rabbit skeletal muscle sarcoplasmic reticulum. (1994) (122)
- Molecular tools to elucidate problems in excitation-contraction coupling. (1990) (121)
- Functional consequences of alterations to polar amino acids located in the transmembrane domain of the Ca2(+)-ATPase of sarcoplasmic reticulum. (1990) (119)
- Defective Endothelium-dependent Relaxation of Vascular Smooth Muscle and Endothelial Cell Ca2+ Signaling in Mice Lacking Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 3* (1997) (119)
- Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice. (2004) (116)
- Correlations between genotype and pharmacological, histological, functional, and clinical phenotypes in malignant hyperthermia susceptibility (2005) (113)
- Sarcolipin Inhibits Polymerization of Phospholamban to Induce Superinhibition of Sarco(endo)plasmic Reticulum Ca2+-ATPases (SERCAs)* (2002) (112)
- A 37-Amino Acid Sequence in the Skeletal Muscle Ryanodine Receptor Interacts with the Cytoplasmic Loop between Domains II and III in the Skeletal Muscle Dihydropyridine Receptor* (1998) (111)
- Physical Interactions between Phospholamban and Sarco(endo)plasmic Reticulum Ca2+-ATPases Are Dissociated by Elevated Ca2+, but Not by Phospholamban Phosphorylation, Vanadate, or Thapsigargin, and Are Enhanced by ATP* (2000) (111)
- Mechanistic models for muscle diseases and disorders originating in the sarcoplasmic reticulum. (2011) (108)
- Studies on the mitochondrial adenosine triphosphatase system. II. The isolation and characterization of an oligomycin-sensitive adenosine triphosphatase from bovine heart mitochondria. (1968) (108)
- Localization of the high affinity calcium binding protein and an intrinsic glycoprotein in sarcoplasmic reticulum membranes. (1980) (106)
- Comparative Proteomics Profiling of a Phospholamban Mutant Mouse Model of Dilated Cardiomyopathy Reveals Progressive Intracellular Stress Responses*S (2008) (106)
- Phospholamban Domain Ib Mutations Influence Functional Interactions with the Ca2+-ATPase Isoform of Cardiac Sarcoplasmic Reticulum* (1998) (105)
- Expression and site-specific mutagenesis of phospholamban. Studies of residues involved in phosphorylation and pentamer formation. (1989) (104)
- Functional consequences of mutations in the beta-strand sector of the Ca2(+)-ATPase of sarcoplasmic reticulum. (1989) (104)
- Functional consequences of alterations to amino acids located in the nucleotide binding domain of the Ca2(+)-ATPase of sarcoplasmic reticulum. (1990) (103)
- Sarcolipin Overexpression in Rat Slow Twitch Muscle Inhibits Sarcoplasmic Reticulum Ca2+ Uptake and Impairs Contractile Function* (2002) (103)
- Calreticulin is a candidate for a calsequestrin-like function in Ca2(+)-storage compartments (calciosomes) of liver and brain. (1990) (103)
- A calmodulin-dependent protein kinase system from skeletal muscle sarcoplasmic reticulum. Phosphorylation of a 60,000-dalton protein. (1982) (102)
- Cardiac-specific elevations in thyroid hormone enhance contractility and prevent pressure overload-induced cardiac dysfunction. (2006) (99)
- Isolation and characterization of tryptic fragments of the adenosine triphosphatase of sarcoplasmic reticulum. (1976) (99)
- Sarcoplasmic reticulum gene expression in pressure overload-induced cardiac hypertrophy in rabbit. (1995) (98)
- Functional consequences of alterations to amino acids located in the catalytic center (isoleucine 348 to threonine 357) and nucleotide-binding domain of the Ca2+-ATPase of sarcoplasmic reticulum. (1989) (97)
- Crystal structure of type I ryanodine receptor amino-terminal β-trefoil domain reveals a disease-associated mutation “hot spot” loop (2009) (96)
- Store overload‐induced Ca2+ release as a triggering mechanism for CPVT and MH episodes caused by mutations in RYR and CASQ genes (2009) (96)
- Transmembrane Helix M6 in Sarco(endo)plasmic Reticulum Ca2+-ATPase Forms a Functional Interaction Site with Phospholamban (1999) (96)
- Structure of the rabbit fast-twitch skeletal muscle Ca2+-ATPase gene. (1988) (95)
- Refinement of diagnostic assays for a probable causal mutation for porcine and human malignant hyperthermia. (1992) (95)
- HSP70 Binds to the Fast-twitch Skeletal Muscle Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA1a) and Prevents Thermal Inactivation* (2004) (95)
- Evidence for genetic heterogeneity of malignant hyperthermia susceptibility. (1992) (91)
- Studies on the mitochondrial adenosine triphosphatase system. 3. Isolation from the oligomycin-sensitive adenosine triphosphatase complex of the factors which bind F-1 and determine oligomycin sensitivity of bound F-1. (1968) (89)
- The Transgenic Expression of Highly Inhibitory Monomeric Forms of Phospholamban in Mouse Heart Impairs Cardiac Contractility* (2000) (88)
- Scanning Mutagenesis Reveals a Similar Pattern of Mutation Sensitivity in Transmembrane Sequences M4, M5, and M6, but Not in M8, of the Ca2+-ATPase of Sarcoplasmic Reticulum (SERCA1a)* (1996) (87)
- Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation (2006) (86)
- Purification, calcium binding properties, and ultrastructural localization of the 53,000- and 160,000 (sarcalumenin)-dalton glycoproteins of the sarcoplasmic reticulum. (1990) (86)
- Effects of cation binding on the conformation of calsequestrin and the high affinity calcium-binding protein of sarcoplasmic reticulum. (1974) (84)
- Studies of the electron-transfer system. LXIV. Role of phospholipid in cytochrome oxidase. (1965) (84)
- Functional consequences of alterations to amino acids located in the hinge domain of the Ca(2+)-ATPase of sarcoplasmic reticulum. (1991) (80)
- Structure–Function Relationships in Ca2+ Cycling Proteins (2002) (79)
- Slow/cardiac sarcoplasmic reticulum Ca2+-ATPase and phospholamban mRNAs are expressed in chronically stimulated rabbit fast-twitch muscle. (1989) (79)
- An Ryr1I4895T mutation abolishes Ca2+ release channel function and delays development in homozygous offspring of a mutant mouse line (2007) (78)
- Cardiac-specific Overexpression of a Superinhibitory Pentameric Phospholamban Mutant Enhances Inhibition of Cardiac Functionin Vivo * (2000) (77)
- Chromosome mapping of five human cardiac and skeletal muscle sarcoplasmic reticulum protein genes. (1993) (77)
- Purification and characterization of the 53,000-dalton glycoprotein from the sarcoplasmic reticulum. (1981) (74)
- Rabbit cardiac and slow‐twitch muscle express the same phospholamban gene (1988) (74)
- Targeted Disruption of the ATP2A1 Gene Encoding the Sarco(endo)plasmic Reticulum Ca2+ ATPase Isoform 1 (SERCA1) Impairs Diaphragm Function and Is Lethal in Neonatal Mice* (2003) (74)
- Characterization of cDNA and genomic DNA encoding SERCA1, the Ca(2+)-ATPase of human fast-twitch skeletal muscle sarcoplasmic reticulum, and its elimination as a candidate gene for Brody disease. (1995) (73)
- Ca2+ dysregulation in Ryr1I4895T/wt mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods (2009) (73)
- Enhanced Ca2+ transport and muscle relaxation in skeletal muscle from sarcolipin-null mice. (2011) (72)
- Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum (2011) (71)
- Characterization of a Ca2+ binding and regulatory site in the Ca2+ release channel (ryanodine receptor) of rabbit skeletal muscle sarcoplasmic reticulum. (1992) (70)
- The role of the skeletal muscle ryanodine receptor gene in malignant hyperthermia. (1992) (69)
- Functional consequences of mutations of conserved amino acids in the beta-strand domain of the Ca2(+)-ATPase of sarcoplasmic reticulum. (1990) (69)
- A Ca++-dependent and -selective ionophore as part of the Ca++ plus Mg++-dependent adenosinetriphosphatase of sarcoplasmic reticulum. (1974) (68)
- Structure of the rabbit phospholamban gene, cloning of the human cDNA, and assignment of the gene to human chromosome 6. (1991) (67)
- Studies on the electron transfer system. LXV. Formation of membranes by purified cytochrome oxidase. (1966) (67)
- The substitution of Arg for Gly2433 in the human skeletal muscle ryanodine receptor is associated with malignant hyperthermia. (1994) (66)
- Monoclonal antibodies to the Ca2+ + Mg2+-dependent ATPase of sarcoplasmic reticulum identify polymorphic forms of the enzyme and indicate the presence in the enzyme of a classical high-affinity Ca2+ binding site (1984) (65)
- Quercetin inhibits Ca2+ uptake but not Ca2+ release by sarcoplasmic reticulum in skinned muscle fibers. (1980) (64)
- Molecular cloning and expression of cDNA encoding a lumenal calcium binding glycoprotein from sarcoplasmic reticulum. (1989) (64)
- Functional Consequences of Mutations of Conserved, Polar Amino Acids in Transmembrane Sequences of the Ca2+ Release Channel (Ryanodine Receptor) of Rabbit Skeletal Muscle Sarcoplasmic Reticulum* (1998) (64)
- Resolution of the calcium transport system of saecoplasmic reticulum. (1975) (63)
- The Molecular Biology of Membranes (1978) (62)
- The nucleotide binding/hinge domain plays a crucial role in determining isoform-specific Ca2+ dependence of organellar Ca(2+)-ATPases. (1992) (62)
- Localization of ionophore activity in a 20,000-dalton fragment of the adenosine triphosphatase of Sarcoplasmic reticulum. (1976) (61)
- Ca2+ Inactivation Sites Are Located in the COOH-terminal Quarter of Recombinant Rabbit Skeletal Muscle Ca2+ Release Channels (Ryanodine Receptors)* (1999) (61)
- Tbx5-dependent pathway regulating diastolic function in congenital heart disease (2008) (60)
- Antibodies as probes for Ca2+ activation sites in the Ca2+ release channel (ryanodine receptor) of rabbit skeletal muscle sarcoplasmic reticulum. (1993) (60)
- Asymmetrical blockade of the Ca2+ release channel (ryanodine receptor) by 12-kDa FK506 binding protein. (1994) (59)
- A proton gradient controls a calcium-release channel in sarcoplasmic reticulum. (1981) (59)
- Ca2+ Signaling in HEK-293 and Skeletal Muscle Cells Expressing Recombinant Ryanodine Receptors Harboring Malignant Hyperthermia and Central Core Disease Mutations* (2005) (58)
- Mutation of Divergent Region 1 Alters Caffeine and Ca2+ Sensitivity of the Skeletal Muscle Ca2+Release Channel (Ryanodine Receptor)* (2000) (58)
- Mutation of glutamate 309 to glutamine alters one Ca(2+)-binding site in the Ca(2+)-ATPase of sarcoplasmic reticulum expressed in Sf9 cells. (1993) (57)
- Characterization of Recombinant Rabbit Cardiac and Skeletal Muscle Ca2+ Release Channels (Ryanodine Receptors) with a Novel [3H]Ryanodine Binding Assay* (1998) (57)
- THE ISOLATION OF A COPPER PROTEIN FROM CYTOCHROME OXIDASE. (1965) (56)
- Functional characterization of alternatively spliced human SERCA3 transcripts. (1998) (56)
- Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by α-crystallin-B (2010) (56)
- Studies on the mitochondrial adenosine triphosphatase system. V. Localization of the oligomycin-sensitivity conferring protein. (1968) (54)
- Complex interactions between skeletal muscle ryanodine receptor and dihydropyridine receptor proteins. (1998) (54)
- Functional Characterization of Mutants in the Predicted Pore Region of the Rabbit Cardiac Muscle Ca2+ Release Channel (Ryanodine Receptor Isoform 2)* (2001) (54)
- The epitope for monoclonal antibody A20 (amino acids 870-890) is located on the luminal surface of the Ca2(+)-ATPase of sarcoplasmic reticulum. (1990) (54)
- Calmidazolium and compound 48/80 inhibit calmodulin-dependent protein phosphorylation and ATP-dependent Ca2+ uptake but not Ca2+-ATPase activity in skeletal muscle sarcoplasmic reticulum. (1984) (54)
- Sarcolipin retention in the endoplasmic reticulum depends on its C-terminal RSYQY sequence and its interaction with sarco(endo)plasmic Ca(2+)-ATPases. (2004) (54)
- Functional consequences of alterations to hydrophobic amino acids located at the M4S4 boundary of the Ca(2+)-ATPase of sarcoplasmic reticulum. (1991) (53)
- Interaction sites among phospholamban, sarcolipin, and the sarco(endo)plasmic reticulum Ca(2+)-ATPase. (2008) (52)
- Functional expression of cDNA encoding the Ca2+ release channel (ryanodine receptor) of rabbit skeletal muscle sarcoplasmic reticulum in COS-1 cells. (1993) (52)
- Molecular cloning and expression of cDNA encoding the 53,000-dalton glycoprotein of rabbit skeletal muscle sarcoplasmic reticulum. (1989) (51)
- Discordance between phenotype and genotype in malignant hyperthermia. (1995) (50)
- Structural determination of the phosphorylation domain of the ryanodine receptor (2012) (50)
- Studies on the mechanims of oxidative phosphorylation. IX. Effect of cytochrome c on energy-linked processes. (1966) (48)
- The fast‐twitch muscle calsequestrin isoform predominates in rabbit slow‐twitch soleus muscle (1989) (48)
- Studies on the mitochondrial adenosine triphosphatase system. I. Restoration of adenosine triphosphate-dependent reactions in salt-extracted submitochondrial particles. (1968) (48)
- Alterations of Phospholamban Function Can Exhibit Cardiotoxic Effects Independent of Excessive Sarcoplasmic Reticulum Ca2+-ATPase Inhibition (2009) (47)
- Refined genetic localization for central core disease. (1993) (47)
- Functional consequences of alterations to Gly310, Gly770, and Gly801 located in the transmembrane domain of the Ca(2+)-ATPase of sarcoplasmic reticulum. (1992) (46)
- Metformin increases degradation of phospholamban via autophagy in cardiomyocytes (2015) (46)
- HEK-293 cells possess a carbachol- and thapsigargin-sensitive intracellular Ca2+ store that is responsive to stop-flow medium changes and insensitive to caffeine and ryanodine (1999) (45)
- HEK-293 cells possess a carbachol- and thapsigargin-sensitive intracellular Ca2+ store that is responsive to stop-flow medium changes and insensitive to caffeine and ryanodine. (1999) (45)
- Isolation of a second form of calsequestrin. (1974) (45)
- Single-channel properties of the recombinant skeletal muscle Ca2+ release channel (ryanodine receptor). (1997) (45)
- Regional mapping of the Batten disease locus (CLN3) to human chromosome 16p12. (1991) (45)
- Studies on the electron transfer system. 68. Formation of membranes as the basis of the reconstitution of the mitochondrial electron transfer system. (1967) (44)
- Co‐expression of slow‐twitch/cardiac muscle Ca2+‐ATPase (SERCA2) and phospholamban (1990) (44)
- Ryanodine receptor type 1 gene mutations found in the Canadian malignant hyperthermia population (2011) (44)
- Chronic SR Ca2+‐ATPase Inhibition Causes Adaptive Changes in Cellular Ca2+ Transport (2003) (41)
- Sites of Regulatory Interaction between Calcium ATPases and Phospholambana (1998) (40)
- Interaction of Nucleotides with Asp351 and the Conserved Phosphorylation Loop of Sarcoplasmic Reticulum Ca2+-ATPase* (1999) (39)
- Studies on the mechanism of oxidative phosphorylation. X. The effect of cytochrome C on energy-linked processes in submitochondrial particles. (1966) (39)
- Assembly of the sarcoplasmic reticulum. Biosynthesis of calsequestrin in rat skeletal muscle cell cultures. (1976) (39)
- Alignment of the major tryptic fragments of the adenosine triphosphatase from sarcoplasmic reticulum. (1980) (39)
- Type 2 ryanodine receptor domain A contains a unique and dynamic α-helix that transitions to a β-strand in a mutant linked with a heritable cardiomyopathy. (2013) (39)
- ATP driven ion pumps: an evolutionary mosaic. (1989) (38)
- Characterization of the ATP-binding domain of the sarco(endo)plasmic reticulum Ca(2+)-ATPase: probing nucleotide binding by multidimensional NMR. (2002) (38)
- Sites of regulatory interaction between calcium ATPases and phospholamban (2004) (37)
- Assembly of the sarcoplasmic reticulum. Biosynthesis of the adenosine triphosphatase in rat skeletal muscle cell culture. (1976) (37)
- Assembly of the Sarcoplasmic Reticulum (1978) (37)
- Site-directed Disulfide Mapping of Helices M4 and M6 in the Ca2+ Binding Domain of SERCA1a, the Ca2+ ATPase of Fast Twitch Skeletal Muscle Sarcoplasmic Reticulum* (1997) (37)
- Site-directed mutagenesis of the Ca2+ ATPase of sarcoplasmic reticulum. (1992) (37)
- Functional consequences of alterations to hydrophobic amino acids located in the M4 transmembrane sector of the Ca(2+)-ATPase of sarcoplasmic reticulum. (1993) (37)
- Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics. (2004) (36)
- Structure-function relationships in Ca(2+) cycling proteins. (2002) (36)
- Positioning of major tryptic fragments in the Ca2+ release channel (ryanodine receptor) resulting from partial digestion of rabbit skeletal muscle sarcoplasmic reticulum. (1993) (35)
- Structure of the rabbit fast-twitch skeletal muscle calsequestrin gene. (1988) (34)
- [27] Isolation of proteins of the sarcoplasmic reticulum (1974) (34)
- Ryanodine sensitizes the cardiac Ca2+ release channel (ryanodine receptor isoform 2) to Ca2+ activation and dissociates as the channel is closed by Ca2+ depletion (2001) (33)
- Mitochondrial "structural protein." A reassessment. (1970) (33)
- Central core disease mutations R4892W, I4897T and G4898E in the ryanodine receptor isoform 1 reduce the Ca2+ sensitivity and amplitude of Ca2+-dependent Ca2+ release. (2004) (32)
- Structure and Function of the Mitochondrial Cristael Membrane (1969) (32)
- Assembly of the sarcoplasmic reticulum. Cell-free synthesis of te Ca2+ + Mg2+-adenosine triphosphatase and calsequestrin. (1980) (32)
- Roles of Conserved P Domain Residues and Mg2+ in ATP Binding in the Ground and Ca2+-activated States of Sarcoplasmic Reticulum Ca2+-ATPase* (2004) (31)
- Differential effects of mercurial compounds on excitable tissues. (1975) (31)
- The genetic basis of malignant hyperthermia. (1992) (31)
- Protocol for the Sequence Analysis of Ryanodine Receptor Subtype 1 Gene Transcripts from Human Leukocytes (2003) (31)
- The preparation of microsomal electron-transfer complexes (1967) (31)
- The NH2 terminus of the (Ca2+ + Mg2+)-adenosine triphosphatase is located on the cytoplasmic surface of the sarcoplasmic reticulum membrane. (1981) (30)
- A comparison of the caffeine halothane muscle contracture test with the molecular genetic diagnosis of malignant hyperthermia. (1991) (30)
- A calmodulin-dependent protein kinase system from skeletal muscle sarcoplasmic reticulum. (1984) (30)
- Role of the Sequence Surrounding Predicted Transmembrane Helix M4 in Membrane Association and Function of the Ca2+ Release Channel of Skeletal Muscle Sarcoplasmic Reticulum (Ryanodine Receptor Isoform 1)* (2004) (29)
- Assembly of the sarcoplasmic reticulum. Biosynthesis of the high affinity calcium binding protein in rat skeletal muscle cell cultures. (1980) (29)
- Analyzing the cardiac muscle proteome by liquid chromatography-mass spectrometry-based expression proteomics. (2007) (29)
- Assembly of the sarcoplasmic reticulum. Synthesis of calsequestrin and the Ca2+ + Mg2+ -adenosine triphosphatase on membrane-bound polyribosomes. (1978) (28)
- Labeling of high affinity ATP binding sites on the 53,000- and 160,000-dalton glycoproteins of the sarcoplasmic reticulum with the photoaffinity probe 8-N3-[alpha-32P]ATP. (1983) (28)
- Novel excitation-contraction uncoupled RYR1 mutations in patients with central core disease (2013) (28)
- Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype (2011) (28)
- Structure, function and biosynthesis of sarcoplasmic reticulum proteins (1979) (27)
- The Calcium Transport ATPase of Sarcoplasmic Reticulum (1976) (27)
- Structural biology: Pumping ions (2000) (27)
- CASQ1 Gene Is an Unlikely Candidate for Malignant Hyperthermia Susceptibility in the North American Population (2013) (25)
- Studies on the electron transfer system. LXVI. Effect of diphosphopyridine nucleotide deficiency on respiration, respiratory control, and phosphorylation in mitochondria. (1966) (25)
- Mutations to Gly2370, Gly2373 or Gly2375 in malignant hyperthermia domain 2 decrease caffeine and cresol sensitivity of the rabbit skeletal-muscle Ca2+-release channel (ryanodine receptor isoform 1). (2001) (22)
- Structure/Function Analysis of the Ca2+ Binding and Translocation Domain of SERCA1 and the Role in Brody Disease of the ATP2A1 Gene Encoding SERCA1 a (1997) (21)
- Detection of a Novel Ryanodine Receptor Subtype 1 Mutation (R328W) in a Malignant Hyperthermia Family by Sequencing of a Leukocyte Transcript (2003) (21)
- Characterization of the adenosinetriphosphatase and calsequestrin isolated from sarcoplasmic reticulum of normal and dystrophic chickens. (1976) (21)
- The Mitochondrial System of Enzymes (1967) (19)
- Identification of Novel Ryanodine Receptor 1 (RyR1) Protein Interaction with Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP)*♦ (2011) (19)
- Bayesian modeling of muscle biopsy contracture testing for malignant hyperthermia susceptibility. (1998) (19)
- Chapter 8 Assembly of the Sarcoplasmic Reticulum during Muscle Development (1985) (19)
- Studies on the electron transfer system: LXIII. Solubilization and fractionation of mitochondrial proteins by succinylation (1965) (19)
- Solubilization and reconstitution of cholinephosphotransferase from sarcoplasmic reticulum: stabilization of solubilized enzyme by diacylglycerol and glycerol. (1985) (18)
- Isolation of the calmodulin‐dependent protein kinase system from rabbit skeletal muscle sarcoplasmic reticulum (1988) (18)
- Tetraphenylboron causes Ca2+ release in isolated sarcoplasmic reticulum and in skinned muscle fibers. (1983) (18)
- Isolation of proteins of the sarcoplasmic reticulum. (1974) (18)
- Trans-aconitate in plant tissues (1964) (17)
- Structure-function relationships in the Ca2+ pump of the sarcoplasmic reticulum. (1992) (16)
- ATP Binding Residues of Sarcoplasmic Reticulum Ca2+‐ATPase (2003) (16)
- Exome analysis identifies Brody myopathy in a family diagnosed with malignant hyperthermia susceptibility (2014) (16)
- Structure-function relationships in the Ca(2+)-binding and translocation domain of SERCA1: physiological correlates in Brody disease. (1998) (16)
- Multipoint mapping of the central core disease locus. (1993) (16)
- Interaction of nucleotides with Asp(351) and the conserved phosphorylation loop of sarcoplasmic reticulum Ca(2+)-ATPase. (1999) (15)
- Reduced threshold for store overload-induced Ca2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease. (2017) (14)
- Deletion of NH2− and COOH‐terminal sequences destroys function of the Ca2+ ATPase of rabbit fast‐twitch skeletal muscle sarcoplasmic reticulum (1993) (14)
- Studies on the electron transfer system. LXIX. "Solubilization" of the mitochondrial inner membrane by sonic oscillation. (1968) (13)
- ASSEMBLY OF THE SARCOPLASMIC RETICULUM Localization by Immunofluorescence of Sarcoplasmic Reticulum Proteins in Differentiating Rat Skeletal Muscle Cell Cultures (2003) (13)
- Functional characterization of alternatively spliced human SERCA3 transcripts. (1998) (13)
- Expression and mutation of Ca2+ ATPases of the sarcoplasmic reticulum. (1989) (13)
- How carefully can we phenotype patients suspected of malignant hyperthermia susceptibility? (1999) (13)
- Probing nucleotide-binding effects on backbone dynamics and folding of the nucleotide-binding domain of the sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase. (2004) (12)
- The Structure of the Ca2+/Mg2+-ATPase of Sarcoplasmic Reticulum (1982) (12)
- STUDIES OF Ca2+ RELEASE FROM SARCOPLASMIC RETICULUM * (1982) (12)
- Biosynthesis of intrinsic sarcoplasmic reticulum proteins during differentiation of the myogenic cell line L6. (1983) (12)
- [78] Extraction and estimation of cytochrome c from mitochondria and submitochondrial particles (1967) (12)
- Biology of Growth Factors (1988) (11)
- Restoration of calcium transport in the trypsin-treated (Ca+ + Mg2+)-dependent adenosine triphosphatase of sarcoplasmic reticulum exposed th sodium dodecyl sulfate. (1976) (11)
- Calcium ATPaseS: contribution of molecular genetics to our understanding of structure and function. (1987) (11)
- Monoclonal antibodies to the Ca2++Mg2+-dependent ATPase of skeletal muscle sarcoplasmic reticulum--cross-reactivity with ATPase isozymes and other Ca2+-binding proteins. (1984) (11)
- Cardiac-specific Overexpression of a Superinhibitory Pentameric Phospholamban Mutant Enhances Inhibition of Cardiac Function in Vivo * (2000) (10)
- Regulatory interactions between calcium ATPases and phospholamban. (1996) (10)
- Structural biology: Calcium callisthenics (2002) (10)
- A cosmid and yeast artificial chromosome contig containing the complete ryanodine receptor (RYR1) gene. (1993) (10)
- Salt-dependent conformational changes in the cell membrane of Halobacterium salinarium. (1971) (10)
- Phospholamban domain I/cytochrome b 5 transmembrane sequence chimeras do not inhibit SERCA2a (1998) (9)
- Molecular Architecture of the Mitochondrion (1971) (9)
- Restoration by fatty acids of active transport in a lactose transport mutant of Escherichia coli. (1973) (8)
- STRUCTURAL ANALYSIS OF THE Ca2+ + Mg2+-ATPase OF SARCOPLASMIC RETICULUM (1985) (8)
- Interactions of the calcium ATPase with phospholamban and sarcolipin: structure, physiology and pathophysiology. (2004) (8)
- Malignant Hyperthermia and Central Core Disease (1998) (8)
- The role of the skeletal muscle ryanodine receptor (RYR1) gene in malignant hyperthermia and central core disease. (1995) (8)
- Amino acid sequence of fast-twitch skeletal muscle calsequestrin (1987) (7)
- Localization of phosphorylated B-crystallin to heart mitochondria during ischemia-reperfusion (2008) (7)
- Surface Particles of Sarcoplasmic Reticulum Membranes (2002) (7)
- The capacity of the sarcoplasmic reticulum for phospholipid synthesis: a developmental study. (1985) (7)
- Phosphorylation of bound adenosine monophosphate in the electron transfer particle, driven by succinate. (1965) (7)
- The Genetic and Physiological Basis of Malignant Hyperthermia (1996) (7)
- Structural and mechanistic implications of the amino acid sequence of calcium-transporting ATPases. (1986) (7)
- [45] Biosynthesis of sarcoplasmic reticulum proteins (1983) (6)
- Calcium transport and release by sarcoplasmic reticulum: a mini-review. (1979) (5)
- Topology and Transmembrane Organization of Ryanodine Receptors (2005) (5)
- Independent synthesis of phospholipid and the intrinsic proteins of the sarcoplasmic reticulum. (1985) (4)
- Two Ca2+ ATPase genes+ (1986) (4)
- Muscle spindles exhibit core lesions and extensive degeneration of intrafusal fibers in the Ryr1(I4895T/wt) mouse model of core myopathy. (2015) (4)
- Studies on the mitochondrial adenosine triphosphatase system. VI. Coupling activity of F1 subunits. (1970) (4)
- Separate effects of mercurial compounds on the ionophoric and hydrolytic functions of the (Ca+++Mg++)-ATPase of sarcoplasmic reticulum (1975) (4)
- Response to “Malignant Hyperthermia — human stress triggering” in reference to original article “Mechanistic models for muscle diseases and disorders originating in the sarcoplasmic reticulum” http://dx.doi.org/10.1016/j.bbamcr.2010.11.009 (2011) (3)
- ZEROING IN ON THE IONOPHORIC SITE OF THE (Ca2++Mg2+)-ATPase (1978) (3)
- Mutational analysis of the role of Lys684 in the Ca(2+)-ATPase of sarcoplasmic reticulum. (1992) (2)
- A711 A COMPARISON OP THE CAFFEINE HALOTHANE CONTRACTURE TEST WITH MOLECULAR GENETICS DIAGNOSIS OF MALIGNANT HYPERTHERMIA (MH) (1990) (2)
- Fast-twitch and slow-twitch/cardiac Ca2+ ATPase genes map to human chromosomes 16 and 12 (1988) (2)
- Mutations in the Skeletal Muscle Ryanodine Receptor (RYR1) Gene Are Linked to Malignant Hyperthermia and Central-Core Disease (1996) (2)
- ryanodine receptor Ca 2+ ion permeation and release from the sarcoplasmic reticulum (2010) (2)
- Calcium oxalate-loaded sarcoplasmic reticulum vesicles from developing skeletal muscle are highly differentiated. (1988) (2)
- [22] cDNA cloning of sarcoplasmic reticulum proteins (1988) (2)
- cDNA cloning of sarcoplasmic reticulum proteins. (1988) (1)
- The Ca2+ ATPase of Cardiac Muscle Sarcoplasmic Reticulum (1987) (1)
- Improvement of Ca2+ Transport and Muscle Relaxation in Skeletal Muscle From Sarcolipin Null Mice (2008) (1)
- Isolation and characterization of tryptic fragments of the sarcoplasmic reticulum adenosine triphosphatase. (1975) (1)
- Chapter 116 – Ryanodine Receptors (2010) (1)
- Assembly of the Sarcoplasmic Reticulum BIOSYNTHESIS OF THE ADENOSINE TRIPHQSPHATASE IN RAT SKELETAL MUSCLE CELL (2002) (1)
- Diagnosis of malignant hyperthermia in swine. (1991) (1)
- Sarcolipin Ablation Increases Ca2+ Pump Efficiency in Mouse Skeletal Muscle (2008) (1)
- Diastolic Properties of the Failing Myocardium (2005) (1)
- Brody’s Syndrome: a Disorder of Calcium Uptake by the Sarcoplasmic Reticulum (1999) (1)
- COMPARTMENTATION OF ORGANIC ACIDS IN PLANT TISSUES (1963) (1)
- Abstract 187: Metformin Increases Degradation of Ubiquitinylated Phospholamban via Autophagy in Cardiomyocytes (2015) (0)
- Expression and mutagenesis of sarcoplasmic reticulum proteins (1992) (0)
- Deficits in Ca2+ Release and in vivo Muscle Strength in Heterozygous I4895T RyR1 Knock-In Mice (2009) (0)
- Calcium pumps and channels in the sarcoplasmic reticulum (1991) (0)
- Diagnosis of malignant hyperthermia. (1990) (0)
- OJ-023 Cardiac-specific Over-expression of Sarcolipin Inhibits the Sarcoplasmic Reticulum Ca^ ATPase (SERCA2a) and Reduces the Cardiac Function in Mice(Excitation-Contraction Coupling/Ion Channel (A) : OJ3)(Oral Presentation (Japanese)) (2004) (0)
- CHAPTER 130 – Ryanodine Receptors (2003) (0)
- Regulation of Sarcoplasmic Reticulum Ca2+ Pumps (2000) (0)
- Localization of Ca + +-Mg + + A TPase and Calsequestrin in Slow-Twitch and Fast-Twitch Myofibers (2003) (0)
- mitochondria during ischemia-reperfusion B-crystallin to heart α Localization of phosphorylated (2012) (0)
- Chapter 4 Calsequestrin (2005) (0)
- The Use of Site-Directed Mutagenesis to Identify Functional Sites in the Ca2+ ATPase (1994) (0)
- [The organization of the electron transport system]. (1965) (0)
- -ATPase of Cardiac Sarcoplasmic Reticulum (SERCA2a) Is Not Altered by Ca/Calmodulin-dependent Phosphorylation or by Interaction with Phospholamban* (1996) (0)
- SR Ca2+-ATPase, mRNA is down-regulated in pressure-overload rabbit hearts (1987) (0)
- A consensus structure for cation pumps. (1988) (0)
- Overexpression of a phospholamban Asp27 to Ala mutant is associated with significant inhibition of cardiac function (1999) (0)
- Arrhythmogenic Propensity in Mice with a Phosphomimetic Mutation of a PKA Site (S2030D) in the Cardiac Ryanodine Receptor (0)
- Amino acid sequence of calsequestrin deduced from cDNA and peptide sequencing (1986) (0)
- A998 BAYESIAN MODELING OF MUSCLE BIOSPY CONTRACTURE TESTING FOR MALIGNANT HYPERTHERMIA (1997) (0)
- POSSIBLE SITES OF ION FLOW IN THE SARCOPLASMIC RETICULUM MEMBRANE (2005) (0)
- Does Central Core Disease have a Neuronal Component (2010) (0)
- Abstract 183: Cardiac Specific Deletion of Tbx5 Causes Left Ventricular Diastolic Dysfunction that can be Rescued by Increased Serca2a Activity (2006) (0)
- Investigation of regions of functional association between phospholamban and the Ca2+ ATPase of sarcoplasmic reticulum*1 (1992) (0)
- skeletal muscle from sarcolipin-null mice transport and muscle relaxation in (2016) (0)
- Structural model of oligomeric assembly of phospholamban (1989) (0)
- Roles of Conserved P Domain Residues and Mg 2 (cid:1) in ATP Binding in the Ground and Ca 2 (cid:1) -activated States of Sarcoplasmic Reticulum Ca -ATPase* (2004) (0)
- Regional MappingoftheBattenDisease Locus(CLN3)to HumanChromosome16p12 (1991) (0)
- In vivo echocardiographic assessment of contractile dysfunction in transgenic mice overexpressing two different mutant forms of phospholamban (1999) (0)
- Molecular cloning of the 53000 dalton glycoprotein of the sarcoplasmic reticulum (1988) (0)
- O127 Increased Serca2a activity can rescue ventricular diastolic dysfunction which is caused by deletion of Tbx5 (2008) (0)
- Isolation and analysis of calsequestrin DNA from rabbit skeletal muscle (1987) (0)
- Nucleotide sequence and the encoded amino acids of human serum albumin mRNA " by Achilles (0)
- Quercetin Interaction with the ( Caz + + M $ ’ )-ATPase of Sarcoplasmic Reticulum * (2001) (0)
- Biosynthesis of sarcoplasmic reticulum proteins. (1983) (0)
- Phospholamban is localized in autophagosome in dilated cardiomyopathy mouse model, TgPLNR9C mice (2016) (0)
- Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1 (2009) (0)
- A new role for type 1 ryanodine receptor (2009) (0)
- Amino acid sequence of rabbit fast-twitch skeletal muscle calsequestrin deduced from cDNA and peptide sequencing ( calsequestrin / sarcoplasmic reticulum / cDNA cloning ) (0)
- Investigation of functional phospholamban associating regions in the Ca2+ ATPase of sarcoplasmic reticulum ☆ (1992) (0)
- Regulation of sarcoplasmic reticulum gene expression in human heart failure (1992) (0)
- Lethal Arg9Cys phospholamban mutation increases the mitochondrial fission protein (Drp‐1) activity (2015) (0)
- Site-specific mutagenesis of phospholamban. Studies of residues involved in pentamer formation and phosphorylation (1989) (0)
- Sarcoplasmic reticulum Ca2+ ATPases (1996) (0)
- Chronic SR Ca 2 (cid:1) -ATPase Inhibition Causes Adaptive Changes in Cellular Ca 2 (cid:1) Transport (2003) (0)
- Asymmetrical blockade of the Ca 2 + release channel ( ryanodine receptor ) by 12-kDa FK 506 binding protein ( sarcopsmc retIculum / r bayer ) (2004) (0)
- Mechanism of phospholamban inhibition of SERCA2a (1999) (0)
- Chapter 2 TOPOLOGY AND TRANSMEMBRANE ORGANIZATION OF RYANODINE RECEPTORS (2018) (0)
- Cardiac overexpression of a mutant form of phospholamban is associated with depressed contractility and hypertrophy (1999) (0)
This paper list is powered by the following services:
