David J. Prof Baylink
#93,310
Most Influential Person Now
David J. Prof Baylink's AcademicInfluence.com Rankings
David J. Prof Baylinkbiology Degrees
Biology
#4347
World Rank
#6491
Historical Rank
Biochemistry
#442
World Rank
#522
Historical Rank

Download Badge
Biology
Why Is David J. Prof Baylink Influential?
(Suggest an Edit or Addition)David J. Prof Baylink's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. (1997) (1116)
- Genetic variability in adult bone density among inbred strains of mice. (1996) (623)
- Fluoride directly stimulates proliferation and alkaline phosphatase activity of bone-forming cells. (1983) (580)
- Inhibition of bone formation during space flight. (1978) (482)
- IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms. (2002) (455)
- Castrated men exhibit bone loss: effect of calcitonin treatment on biochemical indices of bone remodeling. (1989) (427)
- Growth factors for bone growth and repair: IGF, TGFβ and BMP (1996) (416)
- Growth factors to stimulate bone formation (1993) (398)
- Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice. (2000) (391)
- Androgens directly stimulate proliferation of bone cells in vitro. (1989) (389)
- Bone growth factors. (1991) (379)
- Effects of short term administration of recombinant human growth hormone to elderly people. (1990) (375)
- Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways. (2003) (363)
- Isolation of an inhibitory insulin-like growth factor (IGF) binding protein from bone cell-conditioned medium: a potential local regulator of IGF action. (1989) (357)
- Glucocorticoid-induced osteoporosis. (1983) (330)
- Studies on the Mechanisms by Which Insulin-like Growth Factor (IGF) Binding Protein-4 (IGFBP-4) and IGFBP-5 Modulate IGF Actions in Bone Cells (*) (1995) (309)
- Parathyroid hormone stimulates bone formation and resorption in organ culture: evidence for a coupling mechanism. (1981) (247)
- Radioligand receptor assay for 25-hydroxyvitamin D2/D3 and 1 alpha, 25-dihydroxyvitamin D2/D3. (1976) (234)
- Human bone cells in culture metabolize 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3. (1981) (223)
- Age-related decreases in insulin-like growth factor-I and transforming growth factor-beta in femoral cortical bone from both men and women: implications for bone loss with aging. (1994) (222)
- Formation, mineralization, and resorption of bone in vitamin D-deficient rats. (1970) (222)
- Quantitation of growth factors IGF‐I, SGF/IGF‐II, and TGF‐β in human dentin (1990) (218)
- Phosphotyrosyl protein phosphatases. (1989) (217)
- Inhibitory insulin-like growth factor-binding protein: cloning, complete sequence, and physiological regulation. (1990) (213)
- Evidence that IGF-binding protein-5 functions as a growth factor. (2001) (211)
- Quantitative Trait Loci for Femoral and Lumbar Vertebral Bone Mineral Density in C57BL/6J and C3H/HeJ Inbred Strains of Mice (2001) (207)
- Decrease in serum immunoreactive parathyroid hormone in rats and in parathyroid hormone secretion in vitro by 1,25-dihydroxycholecalciferol. (1975) (203)
- Genetic Regulation of Cortical and Trabecular Bone Strength and Microstructure in Inbred Strains of Mice (2000) (203)
- The insulin-like growth factor system and the coupling of formation to resorption. (1995) (198)
- Characterization and assay of tartrate-resistant acid phosphatase activity in serum: potential use to assess bone resorption. (1987) (194)
- Generalized osteoarthritis associated with increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest. Possible mechanism of increased bone density and protection against osteoporosis. (1993) (193)
- Primary structure of human skeletal growth factor: homology with human insulin-like growth factor-II. (1988) (193)
- Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms. (2003) (185)
- Formation, mineralization, and resorption of bone in hypophosphatemic rats. (1971) (182)
- Increased serum 1,25-dihydroxyvitamin D in idiopathic hypercalciuria. (1977) (181)
- Bayesian Shrinkage Estimation of Quantitative Trait Loci Parameters (2005) (177)
- Growth factors for bone growth and repair: IGF, TGF beta and BMP. (1996) (175)
- Up-regulation of the Wnt, Estrogen Receptor, Insulin-like Growth Factor-I, and Bone Morphogenetic Protein Pathways in C57BL/6J Osteoblasts as Opposed to C3H/HeJ Osteoblasts in Part Contributes to the Differential Anabolic Response to Fluid Shear* (2006) (174)
- Skeletal growth factor and other growth factors known to be present in bone matrix stimulate proliferation and protein synthesis in human bone cells (1990) (174)
- Studies of the mechanism by which androgens enhance mitogenesis and differentiation in bone cells. (1990) (172)
- Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities. (1997) (171)
- Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: a potential candidate for fixing IGF-II in human bone. (1991) (168)
- A new rat model simulating some aspects of space flight. (1979) (168)
- Quantitative histological studies on the pathogenesis of uremic bone disease. (1974) (164)
- Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice (1999) (162)
- Exercise and Mechanical Loading Increase Periosteal Bone Formation and Whole Bone Strength in C57BL/6J Mice but Not in C3H/Hej Mice (2000) (161)
- Evidence that anabolic effects of PTH on bone require IGF-I in growing mice. (2001) (157)
- Estrogens in the prevention of osteoporosis in postmenopausal women. (1989) (154)
- LOSS OF PROTEINPOLYSACCHARIDES AT SITES WHERE BONE MINERALIZATION IS INITIATED (1972) (152)
- Effect of combined risedronate and hormone replacement therapies on bone mineral density in postmenopausal women. (2001) (148)
- Characterization of Cells Isolated and Cultured from Human Bone (1984) (141)
- Skeletal alkaline phosphatase activity as a bone formation index in vitro. (1986) (141)
- Estradiol stimulates in vitro the secretion of insulin-like growth factors by the clonal osteoblastic cell line, UMR106. (1989) (139)
- Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair. (2006) (136)
- 1,25-dihydroxycholecalciferol. Effect on skeletal lesions and plasma parathyroid hormone levels in uremic osteodystrophy. (1974) (135)
- Evidence that human bone cells in culture produce insulin-like growth factor-binding protein-4 and -5 proteases. (1994) (135)
- Low‐amplitude, low‐frequency electric field‐stimulated bone cell proliferation may in part be mediated by increased IGF‐II release (1992) (134)
- Prevention of bone loss with tibolone in postmenopausal women: results of two randomized, double-blind, placebo-controlled, dose-finding studies. (2001) (130)
- 1,25-Dihydroxyvitamin D3 differentially regulates the production of insulin-like growth factor I (IGF-I) and IGF-binding protein-4 in mouse osteoblasts. (1991) (129)
- Peripheral monocyte culture supernatants of menopausal women can induce bone resorption: involvement of cytokines. (1993) (129)
- Insulin-like growth factors I and II are present in the skeletal tissues of ten vertebrates. (1990) (128)
- Ovariectomy selectively reduces the concentration of transforming growth factor beta in rat bone: implications for estrogen deficiency-associated bone loss. (1992) (127)
- Changes in markers of bone formation and resorption in a bed rest model of weightlessness (1993) (127)
- Insulin-like Growth Factor-binding Protein 5 (IGFBP-5) Interacts with a Four and a Half LIM Protein 2 (FHL2)* (2002) (127)
- Increased monocyte interleukin-1 activity and decreased vertebral bone density in patients with fasting idiopathic hypercalciuria. (1990) (126)
- Development of a simple valid method for the complete removal of insulin-like growth factor (IGF)-binding proteins from IGFs in human serum and other biological fluids: comparison with acid-ethanol treatment and C18 Sep-Pak separation. (1995) (125)
- A proposed mechanism of the mitogenic action of fluoride on bone cells: inhibition of the activity of an osteoblastic acid phosphatase. (1989) (125)
- Purification of a skeletal growth factor from human bone. (1982) (121)
- Molecular Mechanism of Action of Fluoride on Bone Cells (1998) (120)
- Histomorphometric studies show that bone formation and bone mineral apposition rates are greater in C3H/HeJ (high-density) than C57BL/6J (low-density) mice during growth. (1999) (119)
- Decreased bone formation, mineralization, and enhanced resorption in calcium-deficient rats. (1973) (119)
- Combined magnetic fields increase insulin-like growth factor-II in TE-85 human osteosarcoma bone cell cultures. (1995) (115)
- Human bone cell phenotypes differ depending on their skeletal site of origin. (1995) (114)
- Conditional deletion of insulin-like growth factor-I in collagen type 1alpha2-expressing cells results in postnatal lethality and a dramatic reduction in bone accretion. (2007) (114)
- Development of an immunoassay for human serum osteoclastic tartrate-resistant acid phosphatase. (1990) (113)
- Down‐Regulation of the Serum Stimulatory Components of the Insulin‐like Growth Factor (IGF) System (IGF‐I, IGF‐II, IGF Binding Protein [BP]‐3, and IGFBP‐5) in Age‐Related (Type II) Femoral Neck Osteoporosis (1999) (113)
- Effect of aging on stem cells (2017) (112)
- Alkaline phosphatase levels and osteoprogenitor cell numbers suggest bone formation may contribute to peak bone density differences between two inbred strains of mice. (1998) (112)
- Increases in number and size of osteoclasts in response to calcium or phosphorus deficiency in the rat. (1975) (112)
- Growth hormone replacement therapy improves body composition and increases bone metabolism in elderly patients with pituitary disease. (2000) (112)
- Development, validation, and application of a radioimmunoassay for insulin-like growth factor binding protein-5 in human serum and other biological fluids. (1995) (107)
- Improved method for quantitative determination in serum of alkaline phosphatase of skeletal origin. (1981) (107)
- Fluoride and bovine bone extract influence cell proliferation and phosphatase activities in human bone cell cultures. (1988) (107)
- Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women. (1998) (107)
- Postnatal and Pubertal Skeletal Changes Contribute Predominantly to the Differences in Peak Bone Density Between C3H/HeJ and C57BL/6J Mice (2001) (106)
- Global gene expression analysis in the bones reveals involvement of several novel genes and pathways in mediating an anabolic response of mechanical loading in mice (2005) (105)
- Cobalamin and osteoblast-specific proteins. (1988) (104)
- Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction. (1991) (102)
- Pregnancy-associated plasma protein-A accounts for the insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) proteolytic activity in human pregnancy serum and enhances the mitogenic activity of IGF by degrading IGFBP-4 in vitro. (2001) (102)
- Structure-Function Analysis of the Human Insulin-like Growth Factor Binding Protein-4* (1998) (102)
- Ibandronate produces significant, similar antifracture efficacy in North American and European women: new clinical findings from BONE (2005) (102)
- In vitro synthesis of 1 alpha,25-dihydroxycholecalciferol and 24,25-dihydroxycholecalciferol by isolated calvarial cells. (1980) (102)
- Interactions of growth factors present in bone matrix with bone cells: effects on DNA synthesis and alkaline phosphatase. (1990) (102)
- Genetic variation in femur extrinsic strength in 29 different inbred strains of mice is dependent on variations in femur cross-sectional geometry and bone density. (2005) (101)
- Human Osteoblasts' Proliferative Responses to Strain and 17β‐Estradiol Are Mediated by the Estrogen Receptor and the Receptor for Insulin‐Like Growth Factor I (2002) (101)
- The multi-functional role of insulin-like growth factor binding proteins in bone (2005) (101)
- Quantitation of growth factors IGF-I, SGF/IGF-II, and TGF-beta in human dentin. (1990) (98)
- DISTRIBUTION OF ACID AND ALKALINE PHOSPHATASE ACTIVITY IN UNDEMINERALIZED SECTIONS OF THE RAT TIBIAL DIAPHYSIS (1969) (98)
- DEFICIENT CALCITONIN RESPONSE TO CALCIUM STIMULATION IN POSTMENOPAUSAL OSTEOPOROSIS? (1982) (97)
- Cortical tibial bone volume in two strains of mice: effects of sciatic neurectomy and genetic regulation of bone response to mechanical loading. (1999) (96)
- Systemic administration of insulin-like growth factor (IGF)-binding protein-4 (IGFBP-4) increases bone formation parameters in mice by increasing IGF bioavailability via an IGFBP-4 protease-dependent mechanism. (2001) (95)
- Calcium and phosphorus deficiency in rats: effects on PTH and 1,25-dihydroxyvitamin D3. (1979) (93)
- Comparison of bone formation responses to parathyroid hormone(1-34), (1-31), and (2-34) in mice. (2000) (93)
- Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal. (2003) (93)
- Bone-resorption markers galactosyl hydroxylysine, pyridinium crosslinks, and hydroxyproline compared. (1992) (92)
- Age-related changes in IGFBP-4 and IGFBP-5 levels in human serum and bone: implications for bone loss with aging. (1995) (91)
- Disruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice. (2007) (91)
- Progesterone and promegestone stimulate human bone cell proliferation and insulin-like growth factor-2 production. (1992) (90)
- Recombinant synthesis of insulin-like growth factor-binding protein-4 (IGFBP-4): Development, validation, and application of a radioimmunoassay for IGFBP-4 in human serum and other biological fluids. (1996) (90)
- Clinical use of serum and urine bone markers in the management of osteoporosis (2005) (90)
- Lack of a high prevalence of the BB vitamin D receptor genotype in severely osteoporotic women. (1995) (90)
- Insulin-like growth factor system components and the coupling of bone formation to resorption. (1996) (90)
- Insulin-like growth factor (IGF)-binding proteins in serum--do they have additional roles besides modulating the endocrine IGF actions? (1996) (90)
- Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice. (2013) (89)
- Studies on the potential mediators of skeletal changes occurring during puberty in girls. (1999) (88)
- Effects of Spaceflight on Structural and Material Strength of Growing Bone (1983) (88)
- Multiple osteocalcin fragments in human urine and serum as detected by a midmolecule osteocalcin radioimmunoassay. (1990) (87)
- Nuclear Factor-E2-related Factor-1 Mediates Ascorbic Acid Induction of Osterix Expression via Interaction with Antioxidant-Responsive Element in Bone Cells* (2007) (87)
- Bone formation by osteocytes. (1971) (87)
- Pregnancy-associated plasma protein-A increases osteoblast proliferation in vitro and bone formation in vivo. (2006) (86)
- In vivo bone formation in fracture repair induced by direct retroviral-based gene therapy with bone morphogenetic protein-4. (2003) (86)
- Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity. (2013) (85)
- Phosphotyrosyl-specific protein phosphatase activity of a bovine skeletal acid phosphatase isoenzyme. Comparison with the phosphotyrosyl protein phosphatase activity of skeletal alkaline phosphatase. (1985) (84)
- Genetic control of the rate of wound healing in mice (2001) (84)
- Biochemical markers of bone turnover for the clinical assessment of bone metabolism. (1994) (83)
- Osteogenic protein-1 stimulates proliferation and differentiation of human bone cells in vitro. (1993) (83)
- Development of valid methods to measure insulin-like growth factors-I and -II in bone cell-conditioned medium. (1990) (83)
- Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population. (2001) (83)
- The effects of fluoride therapy on metabolic bone disease. A histologic study. (1967) (83)
- Vitamin D Therapy of Osteoporosis: Plain Vitamin D Therapy Versus Active Vitamin D Analog (D-Hormone) Therapy (1999) (83)
- The anti-bone-resorptive agent calcitonin also acts in vitro to directly increase bone formation and bone cell proliferation. (1988) (82)
- IGF‐II receptor number is increased in TE‐85 osteosarcoma cells by combined magnetic fields (1995) (82)
- Combined magnetic fields increased net calcium flux in bone cells (1994) (80)
- The 24/25-kDa serum insulin-like growth factor-binding protein is increased in elderly women with hip and spine fractures. (1992) (79)
- Insulin‐like Growth Factor (IGF)‐I, ‐II, IGF Binding Proteins (IGFBP)−3, −4, and −5 Levels in the Conditioned Media of Normal Human Bone Cells Are Skeletal Site‐Dependent (1997) (79)
- Plasma prostaglandin E in patients with cancer with and without hypercalcemia. (1976) (79)
- Insulin-like growth factor-binding protein-5 induces a gender-related decrease in bone mineral density in transgenic mice. (2005) (79)
- Development of an MFG-based retroviral vector system for secretion of high levels of functionally active human BMP4. (2001) (78)
- Vanadate stimulates bone cell proliferation and bone collagen synthesis in vitro. (1988) (78)
- Electron microprobe measurements of bone mineralization rate in vivo. (1974) (77)
- Fluoride therapy for osteoporosis: characterization of the skeletal response by serial measurements of serum alkaline phosphatase activity. (1987) (75)
- Role of Osteocyte-derived Insulin-Like Growth Factor I in Developmental Growth, Modeling, Remodeling, and Regeneration of the Bone (2014) (75)
- Evidence for the coupling of bone formation to bone resorption in vitro (1980) (75)
- Elevated prostaglandins and suppressed parathyroid hormone associated with hypercalcemia and renal cell carcinoma. (1975) (73)
- A Missense Mutation in the Mouse Col2a1 Gene Causes Spondyloepiphyseal Dysplasia Congenita, Hearing Loss, and Retinoschisis (2003) (73)
- Analysis of gene expression in the wound repair/regeneration process (2001) (72)
- ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. (2002) (72)
- Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. (2002) (72)
- Purification and characterization of an acid phosphatase that displays phosphotyrosyl-protein phosphatase activity from bovine cortical bone matrix. (1987) (71)
- Evidence that the interaction between insulin-like growth factor (IGF)-II and IGF binding protein (IGFBP)-4 is essential for the action of the IGF-II-dependent IGFBP-4 protease. (2000) (71)
- Quantitative Trait Loci for Femoral and Lumbar Vertebral Bone Mineral Density in C57BL/6J and C3H/HeJ Inbred Strains of Mice (2001) (70)
- In vitro evidence that bone formation may be coupled to resorption by release of mitogen(s) from resorbing bone. (1987) (70)
- Evidence for a role for insulin-like growth factor binding proteins in glucocorticoid inhibition of normal human osteoblast-like cell proliferation. (1996) (70)
- Effect of calcitonin on the rates of bone formation and resorption in the rat. (1969) (70)
- Relationship between trabecular vertebral body density and fractures: a quantitative definition of spinal osteoporosis. (1988) (69)
- Prevention and treatment of glucocorticoid-induced osteoporosis. A pathogenetic perspective. (1992) (69)
- Quantitative Trait Loci for Bone Density in Mice: The Genes Determining Total Skeletal Density and Femur Density Show Little Overlap in F2 Mice (2002) (69)
- Serum Levels of Insulin-Like Growth Factor (IGF); IGF-Binding Proteins-3, -4, and -5; and Their Relationships to Bone Mineral Density and the Risk of Vertebral Fractures in Postmenopausal Women (2006) (69)
- Human skeletal alkaline phosphatase. Kinetic studies including pH dependence and inhibition by theophylline. (1980) (69)
- Regulation of insulin-like growth factor system components by osteogenic protein-1 in human bone cells. (1995) (68)
- Recombinant human insulin-like growth factor-binding protein-5 stimulates bone formation parameters in vitro and in vivo. (1999) (68)
- Digit tip regrowth and differential gene expression in MRL/Mpj, DBA/2, and C57BL/6 mice (2007) (68)
- Mechanical loading-induced gene expression and BMD changes are different in two inbred mouse strains. (2005) (68)
- Local ex vivo gene therapy with bone marrow stromal cells expressing human BMP4 promotes endosteal bone formation in mice (2004) (67)
- Insulin-like growth factor system components in hyperparathyroidism and renal osteodystrophy. (2000) (67)
- Impaired skeletal growth in mice with haploinsufficiency of IGF-I: genetic evidence that differences in IGF-I expression could contribute to peak bone mineral density differences. (2005) (67)
- Incidence of hip fractures in osteoporotic women treated with sodium fluoride (1987) (67)
- The effects of estrone (Ogen) on spinal bone density of postmenopausal women. (1991) (65)
- Fluid Shear Stress Synergizes with Insulin-like Growth Factor-I (IGF-I) on Osteoblast Proliferation through Integrin-dependent Activation of IGF-I Mitogenic Signaling Pathway* (2005) (65)
- Development of a new radioimmunoassay for human osteocalcin: evidence for a midmolecule epitope. (1988) (65)
- Fluoride therapy for the vertebral crush fracture syndrome. A status report. (1989) (65)
- Influence of dietary vitamin D3 on the circulating concentration of its active metabolites in the chick and rat. (1977) (64)
- Retinoic acid regulates insulin-like growth factor-binding protein expression in human osteoblast cells. (1996) (64)
- Recombinant Human Insulin-Like Growth Factor-Binding Protein-5 Stimulates Bone Formation Parameters in Vitro and in Vivo1. (1999) (63)
- Mechanical Strain Stimulates ROS Cell Proliferation Through IGF‐II and Estrogen Through IGF‐I (1999) (63)
- Studies on regulation of insulin-like growth factor binding protein (IGFBP)-3 and IGFBP-4 production in human bone cells. (1992) (63)
- 1,25-Dihydroxyvitamin D3 increases secretion of insulin-like growth factor binding protein-4 (IGFBP-4) by human osteoblast-like cells in vitro and elevates IGFBP-4 serum levels in vivo. (1993) (61)
- Congenic Strains of Mice for Verification and Genetic Decomposition of Quantitative Trait Loci for Femoral Bone Mineral Density (2003) (61)
- Human skeletal growth factor: characterization of the mitogenic effect on bone cells in vitro. (1982) (60)
- Characterization of mitogenic activities extracted from bovine bone matrix. (1986) (60)
- Identification of mouse Duffy antigen receptor for chemokines (Darc) as a BMD QTL gene. (2007) (60)
- Postmenopausal osteoporosis: proposed roles of defective coupling and estrogen deficiency. (1981) (60)
- Extracts of bone contain a potent regulator of bone formation. (1982) (60)
- Vitamin D intoxication in an anephric child. (1975) (59)
- Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older men and women. (2004) (59)
- Effects of Secreted Frizzled‐Related Protein 3 on Osteoblasts In Vitro (2004) (59)
- Quantification of skeletal alkaline phosphatase in osteoporotic serum by wheat germ agglutinin precipitation, heat inactivation, and a two-site immunoradiometric assay. (1994) (58)
- Serum levels of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-1 to -6 and their relationship to bone metabolism in osteoporosis patients. (2003) (58)
- Neuroendocrine modulation of calcitonin and parathyroid hormone in man. (1978) (57)
- Spontaneous Fractures in the Mouse Mutant sfx Are Caused by Deletion of the Gulonolactone Oxidase Gene, Causing Vitamin C Deficiency (2005) (57)
- Alveolar atrophy and decreased skeletal mass of the radius. (1978) (57)
- A time course of bone response to jump exercise in C57BL/6J mice (2002) (57)
- Growth hormone (GH) treatment of GH-deficient children increases serum levels of insulin-like growth factors (IGFs), IGF-binding protein-3 and -5, and bone alkaline phosphatase isoenzyme. (1996) (56)
- An inhibitory insulin-like growth factor binding protein (In-IGFBP) from human prostatic cell conditioned medium reveals N-terminal sequence identity with bone derived In-IGFBP. (1990) (56)
- Influence of phosphate depletion on the biosynthesis and circulating level of 1alpha,25-dihydroxyvitamin D. (1977) (55)
- Bone matrix and mineral abnormalities in postmenopausal osteoporosis. (1982) (55)
- Identification of genetic loci that regulate bone adaptive response to mechanical loading in C57BL/6J and C3H/HeJ mice intercross. (2006) (54)
- Autocrine regulators of MC3T3‐E1 cell proliferation (1993) (54)
- Serum 1,25-Dihydroxyvitamin D: An Outcome Prognosticator in Human Sepsis (2013) (53)
- Systemic factors in alveolar bone loss. (1974) (53)
- Spaceflight Results in Formation of Defective Bone 1 (1985) (53)
- 1,25-Dihydroxyvitamin D3 stimulates both alkaline phosphatase gene transcription and mRNA stability in human bone cells. (1991) (52)
- Serum Levels of Insulin‐like Growth Factor Binding Proteins (IGFBP)–4 and –5 Correlate with Bone Mineral Density in Growth Hormone (GH)–Deficient Adults and Increase with GH Replacement Therapy (1998) (52)
- Ras‐Association Domain Family 1 Protein, RASSF1C, Is an IGFBP‐5 Binding Partner and a Potential Regulator of Osteoblast Cell Proliferation (2005) (52)
- Serum insulin-like growth factor-I, insulin-like growth factor binding proteins, and bone mineral content in hyperthyroidism. (2000) (50)
- Truncation of the amino terminus of PTH alters its anabolic activity on bone in vivo. (1996) (50)
- Effects of recombinant insulin-like growth factor-binding protein-4 on bone formation parameters in mice. (1999) (50)
- Calcium deficiency in fluoride-treated osteoporotic patients despite calcium supplementation. (1996) (49)
- Human prostatic cancer cells, PC3, elaborate mitogenic activity which selectively stimulates human bone cells. (1990) (49)
- Pregnancy-associated Plasma Protein-A Regulates Myoblast Proliferation and Differentiation through an Insulin-like Growth Factor-dependent Mechanism* (2005) (49)
- Evidence that fluoride-stimulated 3[H]-thymidine incorporation in embryonic chick calvarial cell cultures is dependent on the presence of a bone cell mitogen, sensitive to changes in the phosphate concentration, and modulated by systemic skeletal effectors. (1988) (49)
- Endogenous Inhibitor of Bone Cell Proliferation (1981) (49)
- Studies on the Role of Human Insulin‐like Growth Factor‐II (IGF‐II)‐Dependent IGF Binding Protein (hIGFBP)‐4 Protease in Human Osteoblasts Using Protease‐Resistant IGFBP‐4 Analogs (1999) (48)
- Embryonic bone matrix formation is increased after exposure to a low-amplitude capacitively coupled electric field, in vitro. (1986) (48)
- In vivo and in vitro evidence that the high osteoblastic activity in C3H/HeJ mice compared to C57BL/6J mice is intrinsic to bone cells. (2004) (46)
- Basal plasma immunoreactive calcitonin in postmenopausal osteoporosis. (1980) (46)
- Vitamin D-enhanced osteocytic and osteoclastic bone resorption. (1973) (45)
- Whole genome microarray analysis of growth hormone-induced gene expression in bone: T-box3, a novel transcription factor, regulates osteoblast proliferation. (2006) (45)
- Circadian and longitudinal variation of serum C-telopeptide, osteocalcin, and skeletal alkaline phosphatase in C3H/HeJ mice. (2001) (45)
- Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice. (2003) (44)
- Isolation and purification of a low-molecular-weight skeletal growth factor from human bones. (1986) (43)
- Treatment with the Oral Growth Hormone Secretagogue MK‐677 Increases Markers of Bone Formation and Bone Resorption in Obese Young Males (1998) (43)
- Regulation of bone volume is different in the metaphyses of the femur and vertebra of C3H/HeJ and C57BL/6J mice. (2002) (42)
- Phenytoin increases markers of osteogenesis for the human species in vitro and in vivo. (1995) (42)
- Circulating levels of insulin-like growth factor-I and -II, and IGF-binding protein-3 in inflammation and after parathyroid hormone infusion. (1994) (42)
- Genetic variation in bone-regenerative capacity among inbred strains of mice. (2001) (42)
- Inhibition of bone matrix formation, mineralization, and resorption in thyroparathyroidectomized rats. (1973) (42)
- Selective deficiency of 1,25-dihydroxycholecalciferol. A cause of isolated skeletal resistance to parathyroid hormone. (1977) (42)
- Matrix formation and osteoid maturation in vitamin D-deficient rats made normocalcemic by dietary means (1980) (41)
- Acute inhibition of mineralization and stimulation of bone resorption mediated by hypophosphatemia. (1975) (41)
- Human skeletal growth factor stimulates collagen synthesis and inhibits proliferation in a clonal osteoblast cell line (MC3T3‐E1) (1986) (41)
- Serum immunoreactive parathyroid hormone and 25-hydroxyvitamin D in patients with uremic bone diseases. (1975) (41)
- Insulin‐like growth factor binding protein–4 inhibits both basal and IGF‐mediated chick pelvic cartilage growth in vitro (1993) (41)
- Growth factors and electromagnetic fields in bone. (1994) (41)
- Synthetic peptide-based immunoassay for amino-terminal propeptide of type I procollagen: application for evaluation of bone formation. (1993) (41)
- Skeletal scintigraphic changes in osteoporosis treated with sodium fluoride: concise communication. (1984) (41)
- Studies on human pregnancy-induced insulin-like growth factor (IGF)-binding protein-4 proteases in serum: determination of IGF-II dependency and localization of cleavage site. (2000) (40)
- An age-related decrease in the concentration of insulin-like growth factor binding protein-5 in human cortical bone (1995) (40)
- Expression of a Structurally Unique Osteoclastic Protein-tyrosine Phosphatase Is Driven by an Alternative Intronic, Cell Type-specific Promoter* (2003) (40)
- Evidence that human bone cells in culture secrete insulin‐like growth factor (IGF)‐II and IGF binding protein‐3 but not acid‐labile subunit both under basal and regulated conditions (1995) (40)
- Lack of insulin-like growth factor I exaggerates the effect of calcium deficiency on bone accretion in mice. (2003) (39)
- Differential protein profile in the ear-punched tissue of regeneration and non-regeneration strains of mice: a novel approach to explore the candidate genes for soft-tissue regeneration. (2000) (39)
- Total body calcium and long-term calcium balance in chronic renal disease. (1973) (39)
- Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice. (2003) (39)
- Effects of extracellular calcium on insulin‐like growth factor II in human bone cells (1995) (38)
- PTH stimulates the proliferation of TE-85 human osteosarcoma cells by a mechanism not involving either increased cAMP or increased secretion of IGF-I, IGF-II or TGF beta. (1992) (38)
- Regulation of DNA Synthesis in Chick Calvaria Cells by Factors from Bone Organ Culture (1981) (38)
- Acute reduction in osteoclast number during bone repletion. (1982) (38)
- Extracellular signal-regulated kinase-1 and -2 are both essential for the shear stress-induced human osteoblast proliferation. (2004) (38)
- Quantitative Assessment of Forearm Muscle Size, Forelimb Grip Strength, Forearm Bone Mineral Density, and Forearm Bone Size in Determining Humerus Breaking Strength in 10 Inbred Strains of Mice (2001) (38)
- A mouse tumor-derived osteolytic factor stimulates bone resorption by a mechanism involving local prostaglandins production in bone. (1985) (38)
- Skeletal growth factor is produced by human osteoblast-like cells in culture. (1986) (37)
- Effect of insulin-like growth factor-1 (IGF-1) plus alendronate on bone density during puberty in IGF-1-deficient MIDI mice. (2002) (37)
- Molecular cloning and expression of a unique rabbit osteoclastic phosphotyrosyl phosphatase. (1996) (36)
- Osteoblastic Tartrate‐Resistant Acid Phosphatase: Its Potential Role in the Molecular Mechanism of Osteogenic Action of Fluoride (2003) (36)
- Femur Mechanical Properties in the F2 Progeny of an NZB/B1NJ × RF/J Cross Are Regulated Predominantly by Genetic Loci That Regulate Bone Geometry (2006) (36)
- A urine midmolecule osteocalcin assay shows higher discriminatory power than a serum midmolecule osteocalcin assay during short-term alendronate treatment of osteoporotic patients. (2002) (35)
- Histomorphometric analysis of iliac crest bone biopsies in placebo-treated versus fluoride-treated subjects (1995) (35)
- Contribution of marrow stromal cells to the regulation of osteoblast proliferation in rats: evidence for the involvement of insulin-like growth factors. (1991) (35)
- Phenytoin at Micromolar Concentrations is an Osteogenic Agent for Human-mandible-derived Bone Cells in vitro (1995) (35)
- Leptin Receptor (Lepr) Is a Negative Modulator of Bone Mechanosensitivity and Genetic Variations in Lepr May Contribute to the Differential Osteogenic Response to Mechanical Stimulation in the C57BL/6J and C3H/HeJ Pair of Mouse Strains* (2010) (34)
- Clinical performances of galactosyl hydroxylysine, pyridinoline, and deoxypyridinoline in postmenopausal osteoporosis. (1996) (34)
- Monofluorophosphate physiology: the effects of fluoride on bone. (1983) (34)
- Effects of short-term calcium depletion and repletion on biochemical markers of bone turnover in young adult women. (1998) (34)
- Insulin-like growth factor-binding protein-6 produced by human PC-3 prostate cancer cells: isolation, characterization and its biological action. (1996) (34)
- IGF System Components and Their Role in Bone Metabolism (1999) (34)
- Hip mineral density in females with a recent hip fracture. (1992) (33)
- Mitogenic action(s) of fluoride on osteoblast line cells: Determinants of the response In Vitro (1990) (33)
- Inhibition of human osteoblast marker gene expression by retinoids is mediated in part by insulin-like growth factor binding protein-6. (2001) (33)
- Prevention of Bone Loss With Tibolone in Postmenopausal Women: Results of Two Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Studies (2002) (33)
- Expression of the Fibroblast Growth Factor Receptor Genes in Fracture Repair (2002) (33)
- Characterization of a rapidly responding animal model for fluoride-stimulated bone formation. (1986) (32)
- The role of insulin-like growth factor II in magnetic field regulation of bone formation (1994) (32)
- Mapping the dominant wound healing and soft tissue regeneration QTL in MRL × CAST (2005) (32)
- A transmembrane osteoclastic protein-tyrosine phosphatase regulates osteoclast activity in part by promoting osteoclast survival through c-Src-dependent activation of NFkappaB and JNK2. (2007) (32)
- Progesterone Stimulation of Human Insulin-like Growth Factor-binding Protein-5 Gene Transcription in Human Osteoblasts Is Mediated by a CACCC Sequence in the Proximal Promoter* (1999) (32)
- The effects of two diphosphonates on bone metabolism in the rat (1979) (31)
- Phosphotyrosyl protein phosphatases: potential regulators of cell proliferation and differentiation. (1993) (31)
- The Regulation of Endosteal Bone Volume. (1979) (31)
- Effect of beta-aminopropionitrile on bone mechanical properties. (1977) (31)
- An osteoclastic protein-tyrosine phosphatase may play a role in differentiation and activity of human monocytic U-937 cell-derived, osteoclast-like cells. (2004) (31)
- Evaluation of signal transduction mechanisms for the mitogenic effects of prostaglandin E2 in normal human bone cells in vitro (1996) (30)
- Gene expression between a congenic strain that contains a quantitative trait locus of high bone density from CAST/EiJ and its wild-type strain C57BL/6J (2002) (30)
- Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse. (2009) (30)
- Cellular and molecular mechanisms of accelerated fracture healing by COX2 gene therapy: studies in a mouse model of multiple fractures. (2013) (30)
- Effect of Residual Dental Pulp Tissue on Regeneration of Dentin‐pulp Complex: An In Vivo Investigation (2018) (30)
- Spontaneous fracture (sfx): a mouse genetic model of defective peripubertal bone formation. (2000) (30)
- Effects of Recombinant Insulin-Like Growth Factor-Binding Protein-4 on Bone Formation Parameters in Mice1. (1999) (29)
- Studies on the regulation of insulin‐like growth factor binding protein 3 secretion in human osteosarcoma cells in vitro (1994) (29)
- Fluoride therapy for osteoporosis promotes a progressive increase in spinal bone density (1990) (29)
- Effects of calcitonin on bone quality and osteoblastic function (1993) (29)
- Transforming growth factor beta mediates the estrogen induced inhibition of UMR106 cell growth. (1989) (29)
- Osteogenic Protein-1 Stimulates mRNA Levels of BMP-6 and Decreases mRNA Levels of BMP-2 and -4 in Human Osteosarcoma Cells (1997) (29)
- Characterization of the receptor for insulin‐like growth factor II in bone cells (1989) (29)
- A critical evaluation of the effect of population size and phenotypic measurement on QTL detection and localization using a large F2 murine mapping population (2006) (28)
- In vitro metabolism of 25-hydroxyvitamin D3 by isolated rat kidney cells. (1980) (28)
- Effect of low-dose of recombinant human growth hormone on bone metabolism in elderly women with osteoporosis. (2002) (28)
- Genetic regulation of femoral bone mineral density: complexity of sex effect in chromosome 1 revealed by congenic sublines of mice. (2007) (28)
- Differential regulation of pregnancy associated plasma protein (PAPP)-A during pregnancy in human and mouse. (2002) (28)
- Fluoride at mitogenic doses induces a sustained activation of p44mapk, but not p42mapk, in human TE85 osteosarcoma cells. (1997) (28)
- Insulin-like growth factor II and transforming growth factor beta 1 regulate insulin-like growth factor I secretion in mouse bone cells. (1991) (28)
- The diagnosis and treatment of osteoporosis: future prospects. (1999) (28)
- Bone cell mitogenic action of fluoroaluminate and aluminum fluoride but not that of sodium fluoride involves upregulation of the insulin-like growth factor system. (2002) (28)
- Isolation of wound healing/regeneration genes using restrictive fragment differential display-PCR in MRL/MPJ and C57BL/6 mice. (2005) (27)
- Development and Application of a Serum C-Telopeptide and Osteocalcin Assay to Measure Bone Turnover in an Ovariectomized Rat Model (2000) (27)
- Growth factor-induced proliferation of osteoblasts measured by bromodeoxyuridine immunocytochemistry. (1991) (27)
- Growth hormone stimulates cortical bone formation in immature hypophysectomized rats. (1992) (27)
- Regulation of insulin-like growth factor binding protein-5, four and a half lim-2, and a disintegrin and metalloprotease-9 expression in osteoblasts. (2006) (27)
- An osteoclastic protein‐tyrosine phosphatase is a potential positive regulator of the c‐Src protein‐tyrosine kinase activity: A mediator of osteoclast activity (2006) (27)
- Fluoride at mitogenic concentrations increases the steady state phosphotyrosyl phosphorylation level of cellular proteins in human bone cells. (1996) (27)
- BONE FORMATION AND RESORPTION BY OSTEOCYTES (1971) (27)
- Basic science and clinical utility of biochemical markers of bone turnover--a Congress report. (2009) (26)
- Serum insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 levels in aging and age-associated diseases (1997) (26)
- Targeted Overexpression of Osteoactivin in Cells of Osteoclastic Lineage Promotes Osteoclastic Resorption and Bone Loss in Mice (2012) (26)
- Chromosomal regions harboring genes for the work to femur failure in mice (2002) (26)
- Chick osteoblasts contain fluoride-sensitive acid phosphatase activity. (1988) (26)
- Metabolism of 25(OH)D3 to 1,25(OH)2D3 and 24,25(OH)2D3 by chick chorioallantoic cells in culture. (1980) (25)
- High Osteoblastic Activity In C3H/HeJ Mice Compared to C57BL/6J Mice Is Associated with Low Apoptosis in C3H/HeJ Osteoblasts (2006) (25)
- Measurement of bone mineral content in the term and preterm infant. (1987) (25)
- Multiple Genetic Loci From CAST/EiJ Chromosome 1 Affect vBMD Either Positively or Negatively in a C57BL/6J Background (2005) (25)
- Alterations in calcium, phosphorus and C-terminal parathyroid hormone levels in equine acute renal disease. (1986) (25)
- A New Monoclonal Antibody ELISA for Detection and Characterization of C-telopeptide Fragments of Type I Collagen in Urine (2001) (24)
- Evidence that fluoride therapy increases trabecular bone density in a peripheral skeletal site. (1993) (24)
- Evidence that the inhibition of TE85 human bone cell proliferation by agents which stimulate cAMP production may in part be mediated by changes in the IGF-II regulatory system. (1991) (24)
- Effect of skeletal alkaline phosphatase inhibitors on bone cell proliferation in vitro. (1982) (23)
- Stimulation of cellular alkaline phosphatase activity and its messenger RNA level in a human osteosarcoma cell line by 1,25-dihydroxyvitamin D3. (1989) (23)
- Characterization of the IGF regulatory system in bone. (1993) (23)
- Calvarial cells synthesize 1 alpha,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3. (1983) (23)
- Dibutyryl cyclic adenosine monophosphate differentially regulates cell proliferation in low and high alkaline phosphatase SaOS‐2 human osteosarcoma cells: Evidence for mediation by the insulin‐like growth factor‐II system (1993) (22)
- Effect of Combined Risedronate and Hormone Replacement Therapies on Bone Mineral Density in Postmenopausal Women (2001) (22)
- Differential Effects of Two Protein Tyrosine Kinase Inhibitors, Tyrphostin and Genistein, on Human Bone Cell Proliferation as Compared with Differentiation (1998) (22)
- Mouse genetic model for bone strength and size phenotypes: NZB/B1NJ and RF/J inbred strains. (2002) (21)
- Development and evaluation of C-telopeptide enzyme-linked immunoassay for measurement of bone resorption in mouse serum. (2000) (21)
- Cells isolated from embryonic intestine synthesize 1,25-dihydroxyvitamin-D3 and 24,25-dihydroxyvitamin-D3 in culture. (1983) (21)
- Chemical and biological characterization of low-molecular-weight human skeletal growth factor. (1986) (21)
- Stimulation of Bone Formation and Bone Resorption by Fluoride in Thyroparathyroidectomized Rats (1977) (21)
- The effect of prolonged fluoride therapy for osteoporosis: Bone composition and histology (1989) (21)
- Structure and characterization of the human insulin-like growth factor binding protein (IGFBP)-6 promoter: identification of a functional retinoid response element. (2001) (21)
- Insulin‐Like Growth Factor I Effect on the Number of Osteoblast Progenitors Is Impaired in Ovariectomized Mice (2002) (21)
- Demonstration of reduced mitogenic and osteoinductive activities in demineralized allogeneic bone matrix from vitamin D-deficient rats. (1988) (21)
- Regulation of bone repletion in rats subjected to varying low-calcium stress. (1984) (20)
- Low dose phenytoin is an osteogenic agent in the rat (2004) (20)
- New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129×1/SvJ inbred strains of mice (2006) (20)
- Osteoporosis: radiographic detection of fluoride-induced extra-axial bone formation. (1986) (20)
- Hypercalcemia induced by prostaglandin E2 in thyroparathyroidectomized but not intact rats. (1977) (20)
- Hypercalcemia, Excessive Bone Resorption, and Neutrophilia in Mice Bearing a Mammary Carcinoma (1983) (19)
- Insulin-like growth factor-I and insulin-like growth factor-II induce c-fos in mouse osteoblastic cells (1990) (19)
- Prevention of colorectal cancer with vitamin D (2010) (19)
- HSV-1 amplicon-mediated transfer of 128-kb BMP-2 genomic locus stimulates osteoblast differentiation in vitro. (2004) (19)
- Disruption of Four-and-a-Half LIM 2 Decreases Bone Mineral Content and Bone Mineral Density in Femur and Tibia Bones of Female Mice (2006) (19)
- Use of 1,25(OH)2-vitamin D3 to separate 'types' on renal osteodystrophy. (1977) (19)
- Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen. (1989) (19)
- The effects of phosphate depletion on bone. (1978) (19)
- Fluoride Therapy for Osteoporosis (2001) (18)
- Mapping quantitative trait loci that influence blood levels of alkaline phosphatase in MRL/MpJ and SJL/J mice. (2004) (18)
- Novel loci regulating bone anabolic response to loading: expression QTL analysis in C57BL/6JXC3H/HeJ mice cross. (2007) (18)
- Local administration of AAV-DJ pseudoserotype expressing COX2 provided early onset of transgene expression and promoted bone fracture healing in mice (2015) (18)
- An Improved Mouse Sca-1+ Cell-Based Bone Marrow Transplantation Model for Use in Gene- and Cell-Based Therapeutic Studies (2006) (18)
- Phenytoin and fluoride act in concert to stimulate bone formation and to increase bone volume in adult male rats (1995) (18)
- The selective cyclooxygenase-2 inhibitor celecoxib reduces bone resorption, but not bone formation, in ovariectomized mice in vivo. (2007) (18)
- Mechanism of mitogenic action of aluminum ion on human bone cells: potential involvement of the insulin-like growth factor regulatory system. (1993) (18)
- Beta 2-microglobulin is not a bone cell mitogen. (1989) (18)
- Sca-1+ Hematopoietic Cell-based Gene Therapy with a Modified FGF-2 Increased Endosteal/Trabecular Bone Formation in Mice. (2007) (18)
- Incorporation of sodium fluoride into cortical bone does not impair the mechanical properties of the appendicular skeleton in rats (1992) (17)
- Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ x SJL/J) F(2) mice. (2002) (17)
- Radioligand Receptor Assay for 25-Hydroxyvitamin D2/D3 and la,25-Dihydroxyvitamin D2/D3 APPLICATION TO HYPERVITAMINOSIS D MMu (17)
- Characterization of an animal model of pregnancy-induced vitamin D deficiency due to metabolic gene dysregulation. (2014) (17)
- Osteogenic protein-1 stimulates production of insulin-like growth factor binding protein-3 nuclear transcripts in human osteosarcoma cells. (1997) (17)
- Concentrations of insulin-like growth factor (IGF)-I, -II, and IGF binding protein-4, and -5 in human bone cell conditioned medium do not change with age (2000) (17)
- Spinal fractures during fluoride therapy for osteoporosis: Relationship to spinal bone density (1992) (17)
- Identification of Novel Genetic Loci for Bone Size and Mechanosensitivity in an ENU Mutant Exhibiting Decreased Bone Size (2004) (17)
- A genomewide screening of N-ethyl-N-nitrosourea-mutagenized mice for musculoskeletal phenotypes. (2003) (17)
- Further evidence supporting the phosphate leak hypothesis of idiopathic hypercalciuria. (1978) (17)
- Bone repletion in calcium deficient rats fed a high calcium diet (2005) (17)
- Copurification of osteolytic and transforming growth factor beta activities produced by human lung tumor cells associated with humoral hypercalcemia of malignancy. (1989) (16)
- Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption (1994) (16)
- Localization of the IGF binding domain and evaluation of the role of cysteine residues in IGF binding in IGF binding protein-4. (2001) (16)
- Sequence comparison and predicted structure for the four exon-encoded regions of human insulin-like growth factor binding protein 4. (1995) (16)
- Conditional deletion of IGF-I in osteocytes unexpectedly accelerates bony union of the fracture gap in mice. (2016) (16)
- Construction of a Tc1-like transposon Sleeping Beauty-based gene transfer plasmid vector for generation of stable transgenic mammalian cell clones. (2002) (16)
- Development and Application of a Synthetic Peptide-Based Osteocalcin Assay for the Measurement of Bone Formation in Mouse Serum (2000) (16)
- Evidence that human bone cells in culture contain binding sites for osteogenic protein-1. (1994) (16)
- Identification of quantitative trait loci that regulate obesity and serum lipid levels in MRL/MpJ × SJL/J inbred mice Published, JLR Papers in Press, October 27, 2005. (2006) (16)
- Purification and N-terminal amino acid sequence of the tartrate-resistant acid phosphatase from human osteoclastoma: evidence for a single structure. (1990) (15)
- The role of IGF system in the rise and fall in bone density with age. (2007) (15)
- Vitamin D-enhanced osteoclastic bone resorption at vascualr canals. (1974) (15)
- Osteogenic actions of phenytoin in human bone cells are mediated in part by TGF‐β1 (1996) (15)
- The Effect of βAminopropionitrile (BAPN) on Bone Mineralization 1 (1977) (14)
- Immobilization and its effect on bone repletion in calcium-deficient rats fed a high calcium diet (1978) (14)
- Normal growth despite GH, IGF-I and IGF-II deficiency. (1999) (14)
- Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F2 mice (2002) (14)
- Acute Effects of Calcitonin Nasal Spray on Serum C-telopeptide of Type 1 Collagen (CTx) Levels in Elderly Osteopenic Women with Increased Bone Turnover (2004) (14)
- Mapping quantitative trait loci that influence serum insulin-like growth factor binding protein-5 levels in F2 mice (MRL/MpJ X SJL/J). (2003) (14)
- Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice. (2002) (14)
- Bone repletion in vitro: evidence for a locally regulated bone repair response to PTH treatment. (1988) (14)
- Synthesis of 1,25-dihydroxycholecalciferol and 24,25-dihydroxycholecalciferol by calvarial cells. Characterization of the enzyme systems. (1987) (14)
- Detecting Novel Bone Density and Bone Size Quantitative Trait Loci Using a Cross of MRL/MpJ and CAST/EiJ Inbred Mice (2007) (14)
- Effects of medroxyprogesterone acetate on some parameters of calcium metabolism in patients with glucocorticoid-induced osteoporosis. (1991) (14)
- Skeletal alkaline phosphatase activity in serum. (1995) (14)
- Bone cells on microcarrier spheres. (1983) (14)
- Factors affecting bone enzymatic activity in vitamin D-deficient rats. (1971) (14)
- Covalent interaction between proform of eosinophil major basic protein (proMBP) and pregnancy-associated plasma protein-A (PAPP-A) is a cell-mediated event and required for proMBP inhibition of the catalytic activity of PAPP-A. (2004) (14)
- Modifications of the fibroblast growth factor‐2 gene led to a marked enhancement in secretion and stability of the recombinant fibroblast growth factor‐2 protein (2007) (13)
- Mapping genetic loci that regulate lipid levels in a NZB/B1NJ×RF/J intercross and a combined intercross involving NZB/B1NJ, RF/J, MRL/MpJ, and SJL/J mouse strains Published, JLR Papers in Press, May 13, 2007. (2007) (13)
- Biochemical Markers For Bone Formation and Bone Resorption (1989) (13)
- The effect of prolonged fluoride therapy for osteoporosis: bone composition and histology. (1990) (13)
- Mechanistic study of the cause of decreased blood 1,25-Dihydroxyvitamin D in sepsis (2019) (13)
- Altered bone turnover during spaceflight. (1979) (13)
- Efficacy of long-term fluoride and calcium therapy in correcting the deficit of spinal bone density in osteoporosis. (1989) (13)
- Effect of bone matrix-derived growth factors on skull and tibia in the growing rat. (1988) (12)
- The diagnosis and management of osteoporosis (2000) (12)
- Pore Size Measurements and Some Age-Related Changes in Human Alveolar Bone and Rat Femur (1977) (12)
- Galactosyl Hydroxylysine and Deoxypyridinoline: A Methodological Comparison (1993) (12)
- Evaluation of IGF System Component Levels and Mitogenic Activity of Uremic Serum on Normal Human Osteoblasts (2000) (12)
- Monofluorophosphate is hydrolyzed by alkaline phosphatase and mimics the actions of NaF on skeletal tissues,In Vitro (2007) (12)
- Pretreatment with low doses of norethindrone potentiates the osteogenic effects of fluoride on human osteosarcoma cells (1995) (12)
- Evaluation of the usefulness of serum phosphatases and osteocalcin as serum markers in a calcium depletion-repletion rat model (1991) (12)
- Quantitative trait loci that harbor genes regulating muscle size in (MRL/MPJ × SJL/J) F2 mice (2002) (12)
- Bone-derived factors active on bone cells (2006) (12)
- A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways. (2008) (11)
- The role of skeletal calcium deficiency in postmenopausal osteoporosis (1986) (11)
- Effects of dietary calcium depletion and repletion on dynamic determinants of tibial bone volume in two inbred strains of mice. (2000) (11)
- CHAPTER 19 – Role of Growth Hormone/Insulin-like Growth Factor Axis (1999) (10)
- Osteocyte-Derived Insulin-Like Growth Factor I Is Not Essential for the Bone Repletion Response in Mice (2015) (10)
- Regulation of plasma 1α,25 dihydroxyvitamin D by calcium and phosphate (1975) (10)
- Evidence that tartrate-resistant acid phosphatases from osteoclastomas and hairy cell leukemia spleen are members of a multigene family. (1991) (10)
- Differential response in alveolar bone osteoclasts residing at two different bone sites (1984) (10)
- Effect of sodium fluoride on bone density in chickens (1992) (10)
- Effect of fibrillar structure of pericanalicular and intercanalicular bone on X‐ray absorption (1970) (10)
- Construction of a BAC Contig for a 3 cM Biologically Significant Region of Mouse Chromosome 1 (2004) (9)
- Osteoporosis in corticosteroid-treated asthmatic patients: clinical correlates. (1993) (9)
- Vitamin D status and metabolism in an ovine pregnancy model: effect of long-term, high-altitude hypoxia. (2016) (9)
- Studies on regulation of IGF (insulin-like growth factor)-binding protein (IGFBP) 4 proteolysis by pregnancy-associated plasma protein-A (PAPP-A) in cells treated with phorbol ester. (2004) (9)
- Effect of dichloromethylene diphosphonate on bone metabolism in calcium and phosphorus-depleted rats. (1983) (9)
- The Effect of Vitamin D Deficiency on Bone Repletion (1981) (9)
- Excretion of Sweat and Urine Pyridinoline Crosslinks in Healthy Controls and Subjects with Established Metabolic Bone Disease (2001) (9)
- Progress toward skeletal gene therapy. (2004) (8)
- Opposing Changes in Osteocalcin Levels in Bone vs Serum During the Acquisition of Peak Bone Density in C3H/HeJ and C57BL/6J Mice (2002) (8)
- Effect of space flight on bone strength. (1979) (8)
- Preliminary report: correlation of total body calcium (bone mass), as determined by neutron activation analysis with regional bone mass as determined by photon absorption (1975) (8)
- Evidence for arrested bone formation during spaceflight (1982) (8)
- Fluoride therapy for osteoporosis: A review of dose response, duration of treatment, and skeletal sites of action (2007) (8)
- Theoretical physical chemical studies of the cause of fluoride‐induced osteomalacia (1990) (8)
- Sodium fluoride does not increase human bone cell proliferation or protein synthesis in vitro (2004) (8)
- Idiopathic hypercalciuria: The 'phosphate leak' hypothesis and the effects of oral phosphate supplement (1977) (8)
- Mouse chromosome 9 quantitative trait loci for soft tissue regeneration: Congenic analysis and fine mapping (2007) (7)
- Identification and characterization of novel IGFBP5 interacting protein: evidence IGFBP5-IP is a potential regulator of osteoblast cell proliferation. (2006) (7)
- Sodium fluoride does not increase human bone cell proliferation or protein synthesis in vitro. (1992) (7)
- Marrow Stromal Cell-Based Cyclooxygenase 2 Ex Vivo Gene-Transfer Strategy Surprisingly Lacks Bone-Regeneration Effects and Suppresses the Bone-Regeneration Action of Bone Morphogenetic Protein 4 in a Mouse Critical-Sized Calvarial Defect Model (2009) (7)
- Effects of calcium depletion and repletion on serum insulin-like growth factor I and binding protein levels in weanling rats. (1998) (6)
- Application of Genomic Resources and Gene Expression Profiles to Identify Genes That Regulate Bone Density (2003) (6)
- Sca-1(+) hematopoietic cell-based gene therapy with a modified FGF-2 increased endosteal/trabecular bone formation in mice. (2007) (6)
- Pharmacokinetic profile of a new fluoride preparation: Sustained-release monofluorophosphate (2004) (6)
- Structural and functional analysis of the 5'-flanking region of the human insulin-like growth factor binding protein (IGFBP)-4 gene. (1997) (6)
- Dexamethasone enhances the osteogenic effects of fluoride in human TE85 osteosarcoma cellsin vitro (1996) (6)
- Analytical and clinical evaluation of the Bio-Rad HPLC kit for measurement of type I collagen cross links (2003) (5)
- Intestinal metabolism and portal venous transport of 1,25(OH)2D3, 25(OH)D3, and vitamin D3 in the rat. (1985) (5)
- Systemic influences on the bone response to dental and orthopedic implants. (1988) (5)
- Quantitation of growth factors in ossein-mineral-compound. (1991) (5)
- Experiment K305: Quantitative analysis of selected bone parameters (1981) (5)
- Increased immunoreactive calcitonin in idiopathic hypercalciuria. (1981) (5)
- The increase in spinal bone density that occurs in response to fluoride therapy for osteoporosis is not maintained after the therapy is discontinued (2005) (5)
- The regulation of endosteal bone volume. (1979) (5)
- Development of a synthetic peptide-based tartrate-resistant acid phosphatase radioimmunoassay for the measurement of bone resorption in rat serum (2002) (4)
- [27] Purification of bovine skeletal growth factor (1987) (4)
- On fluoride and bone strength (2004) (4)
- 1,25-Dihydroxyvitamin D: Response to and Production by Bone Cells (1984) (4)
- The Actions and Therapeutic Applications of 1α-Hydroxylated Derivatives of Vitamin D (1994) (4)
- BEYOND CARRIER PROTEINS IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms (2002) (4)
- Protein Tyrosine Kinase Inhibitors Block the Stimulatory Actions of Phosphotyrosine Phosphatase Inhibitors to Increase Cell Proliferation, Alkaline Phosphatase Activity, and Collagen Synthesis in Normal HumanBone Cells (2000) (4)
- Resorption of bone implants (1978) (4)
- Clinical Use of Fluoride in Osteoporosis (1990) (4)
- In vitro evidence that local and systemic skeletal effectors can regulate3[H]-thymidine incorporation in chick calvarial cell cultures and modulate the stimulatory actions(s) of embryonic chick bone extract (2007) (4)
- Parathyroid hormone release is not associated with acute sympathetic arousal in goats. (1979) (3)
- Mapping of the chromosome 17 BMD QTL in the F2 male mice of MRL/MpJ × SJL/J (2008) (3)
- Bone mineralization and metabolism of3H-25-hydroxyvitamin D3 in thyroparathyroidectomized rats treated with parathyroid extract (1979) (3)
- Fluoride therapy for the vertebral crush fracture syndrome: A status report (1990) (3)
- Epiphyseal Plate Shear Strength in Rats Treated with a Diphosphonate (1980) (3)
- Bone cell and hormone changes during bone repletion. (1982) (3)
- Differences in exposure to stimulatory and inhibitory components of the insulin-like growth factor (IGF) system in patients with femoral neck versus trochanteric fracture. (2005) (3)
- Effect of progesterone on the mRNA levels of insulin-like-growth factors (IGFs), IGF-binding proteins (JGFBPs) and type-1 and -type-2 igfreceptors in human osteoblastic cells (1992) (3)
- Specific binding of estrogen to nuclei from Japanese quail kidney cells. (1978) (3)
- The effects of the insulin-like growth factors and transforming growth factor β on the jun proto-oncogene family in MC3T3-E1 cells (1994) (3)
- Comparison of rates of change in bone density as measured by dual-energy X-ray absorptiometry and quantitative computed tomography in osteoporotic females treated with fluoride. (1998) (3)
- 24,25(OH)2D3, bone formation, and bone resorption in vitamin D-deficient, azotemic rats (1984) (3)
- The effects of the insulin-like growth factors and transforming growth factor beta on the Jun proto-oncogene family in MC3T3-E1 cells. (1994) (3)
- The effect of beta-aminopropionitrile (BAPN) on bone mineralization. (1977) (3)
- Rationale for active vitamin D analog therapy in senile osteoporosis (2009) (3)
- Near-total parathyroidectomy in chronic dialysis patients. (1976) (3)
- Serum fluoride and serum osteocalcin levels in response to a novel sustained-release monofluorophosphate preparation: Comparison with plain monofluorophosphate (2005) (3)
- A Correction: Inhibitory Activity in the Conditioned Medium of Embryonic Chick Bones Is Due to Thymidine (1984) (2)
- APPLICATION TO HYPERVITAMINOSIS D (1976) (2)
- Effect of treatment with parathyroid extract on bone parameters and metabolism of 3H-25-hydroxyvitamin D3 in Hypocalcemic Thyroparathyroidectomized Rats (1979) (2)
- Isolation and partial purification of a putative coupling factor from human bone. (1981) (2)
- Implants: Systemic influences. (1987) (2)
- Purification of bovine skeletal growth factor. (1987) (2)
- Plasma immunoreactive calcitonin in postmenopausal osteoporosis (1979) (2)
- Transgenic overexpression of pregnancy-associated plasma protein-A in skeletal muscle of mice increases myofiber size and central nucleation in sedentary muscle and promotes muscle regeneration in the injured muscle. (2012) (2)
- and width in mice I collagen-expressing cells reduces bone length α type II Disruption of insulin-like growth factor-I expression in (2015) (2)
- Estrogen receptors in the regulation of skeletal maturation and the GH/IGF-I axis in male mice. (2000) (2)
- Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3h/HeJ inbred strains of mice. (2001). (2005) (2)
- Bovine skeletal growth factor stimulates protein phosphorylation of chicken bone cells in vitro. (1988) (2)
- Increased bone microhardness in fluoride treated rats (1974) (2)
- A platform of high-efficiency nonviral gene transfer in mouse osteoblast cells in vitro (2006) (2)
- A role for prostaglandin E (PGE) in the hypercalcemia of human cancer (1975) (2)
- Coupled bone metabolism in vitro: embryonic chick limbs in organ culture. (1982) (2)
- An improved technique for rapid autoradiography of cells and tissue sections (2004) (2)
- Osteogenic Actions of Fluoride: Its Therapeutic Use for Established Osteoporosis (2013) (2)
- 1.25-Dihydroxyvitamin D3 increases secretion of inhibitory insulin-like growth factor binding protein-4 and inhibits mitogenesis in osteoblastic cells (1992) (2)
- METHOD FOR MEASUREMENT OF DENSITY AND CROSS-SECTIONAL AREA OF THE FEMORAL CORTEX USING COMPUTED TOMOGRAPHY (1985) (2)
- Drug therapy for prevention and treatment of osteoporosis (1989) (2)
- CHAPTER 48 – Fluoride Therapy of Established Osteoporosis (1999) (1)
- Predictions on future diagnosis and treatment of osteoporosis: Results and discussion of a recent opinion poll (1995) (1)
- Serum fluoride and bone formation parameters in response to a novel sustained release monofluorophosphate (MEP-SR), comparison with plain MFP (2006) (1)
- Evidence for a lack of functional receptors for nerve growth factor (NGF) in chick bone cells in vitro (1992) (1)
- Development of nonviral basic FGF expression plasmids for ex vivo gene therapy of bone (1999) (1)
- Preliminary Results of the Antineoplastic Activity of a Marine Terpenoid in Human Cancer Cell Lines (2000) (1)
- BONE DENSITY IN THE SPINE BY CT AND IN THE RADIUS BY PHOTON ABSORPTION IN OSTEOPOROSIS (1983) (1)
- Biochemical Markers in the Diagnosis and Treatment of Osteoporosis (1996) (1)
- Effects of zinc and other nutritional factors on insulin-like growth factor I and insulin-like growth factor binding proteins in postmenopausal women 1 – 3 (1)
- [Autocrine regulation of cell proliferation and secretion of insulin-like growth factor I (IGF-I) in osteoblastic cell line MC3T3-E1]. (1994) (1)
- Molecular Genetic Studies of Bone Mechanical Strain and of Pedigrees with Very High Bone Density (2002) (0)
- The skeletal concentration of transforming growth factor beta in rats is selectively diminished by ovariectomy (1992) (0)
- OR5,27 A novel approach involving a sensitized chemical mutagenesis screen to identify genes that interact with GH signaling pathway to regulate skeletal phenotype (2010) (0)
- Fluoride at Mitogenic Doses Induces a Sustained Activation of p44, but Not p42, in Human TE85 Osteosarcoma Cells* (1997) (0)
- Inhibition ofBoneMiatrix Formation, Mineralization, andResorption in Thyroparathyroidectomized Rats (1973) (0)
- Concomitant phenytoin therapy doubles the osteogenic and densitometric effect of fluoride therapy in osteoporosis (2006) (0)
- AUGMENTATING OSTEOINTEGRATION OF PROSTHETIC MPLANT DEVICES (2017) (0)
- Resorption of bone implants. The effect of in vivo incorporation of a diphosphonate and fluoride on resorption. (1978) (0)
- changes are different in two inbred mouse strains Mechanical loading-induced gene expression and BMD (2015) (0)
- [Effect of fluorides on the mineralization of rat bones]. (1971) (0)
- ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size. (2013) (0)
- Patients with Van Buchem's disease, an osteosclerotic genetic disease, have a higher bone density and a greater polar moment of inertia. (2000) (0)
- Increased Immunoreactive CalcitHin in Idiopathic Hypercalciuria (1981) (0)
- Purification of a tartrate-resistant acid phosphatase (TrACP) from bovine cortical bone matrix (1986) (0)
- ImprovedMethodfor QuantitativeDeterminationin Serumof Alkaline (2004) (0)
- 23: DISCOVERY OF A NOVEL OUTCOME PROGNOSTICATOR FOR SEPSIS WITH THERAPEUTIC IMPLICATIONS (2012) (0)
- EVIDENCE OF A ROLE FOR VITAMIN D AND TRANSFORMING GROWTH FACTOR P IN OSTEOINDUCTION (1991) (0)
- The therapy of osteoporosis. (1969) (0)
- 794. Retroviral-Based Gene Therapy with Cyclo-Oxygenase-2 Promotes Bony Union and Accelerates Fracture Healing in the Rat (2006) (0)
- Bone growth-promoting composition (1992) (0)
- 91136133 Effects of medroxyprogesterone acetate on some parameters of calcium metabolism in patients with glucocorticoid-induced osteoporosis (1991) (0)
- Bone resorption in vitro: Effects of a physiologic dose of parathyroid hormone (1979) (0)
- Effects of insulin like growth factors I & II on cell activity and calcitriol receptor levels in human bone cells in vitro (1995) (0)
- Physical and biochemical changes occurring in bone as a result of gravity counteraction Semiannual report (1967) (0)
- Aminoterminal procollagen 1 (i) peptides (1993) (0)
- 038 Digit Tip Regeneration and Global Gene Expression Profiling in the MRL SuperHealer Mouse (2008) (0)
- 449. Sca-1+ Cell-Based Gene Therapy with a Modified Fibroblast Growth Factor 2 (FGF2) Increased Endosteal/Trabecular Bone Formation in Mice (2006) (0)
- A process for the release of ligand-binding proteins (1994) (0)
- Thyroparathyroidectomized Rats Stimulation of Bone Formation and Bone Resorption by Fluoride in (2011) (0)
- The effect of vitamin D deficiency on bone replacement. (1981) (0)
- Normophosphatemic vitamin D-resistant osteomalacia in a patient with normal calcium and fat absorption. (1971) (0)
- A NEW SURGICAL TECHNIQUE THAT ENHANCES VECTOR APPLICATION FOR GENE THERAPY IN THE RAT FEMUR FRACTURE MODEL.: 187 (2004) (0)
- Evidence that second messenger responses are differentiation stage dependent (1993) (0)
- [Treatment of osteoporosis with fluoride]. (1993) (0)
- regulator of osteoblast cell proliferation interacting protein: evidence IGFBP5-IP is a potential Identification and characterization of novel IGFBP5 (2016) (0)
- Humoral Hypercalcemia of Malignancy Activities Produced by Human Lung Tumor Cells Associated β Copurification of Osteolytic and Transforming Growth Factor Updated (2006) (0)
- Biophysical stimulation of tissue healing mediated by IGF-II (1992) (0)
- Isolated skeletal resistance to parathyroid hormone (PTH): correction with 1,25 dihydroxycholecalciferol (DHCC) therapy (1977) (0)
- Coupling of Bone Formation and Bone Resorption: A Model (1998) (0)
- OR06-1 CRE/LOXP-MEDIATED INACTIVATION OF IGF-I GENE IN TYPE I COLLAGEN EXPRESSING CELLS PRODUCES NEONATAL LETHALITY AND A DRAMATIC EFFECT ON SKELETAL PHENOTYPE (2006) (0)
- Commentaryon "Restoration of Bone Mass in the Severely Osteopenic Senescent Rat' (2001) (0)
- Upregulation of a novel autocrine synthetic pathway for 1,25-dihydroxy-vitamin D3 in intestinal epithelial cells: P-0068. (2008) (0)
- Contents, Vol. 17, Supplement 1, 1983 (1983) (0)
- Characterization of the responsiveness of the preosteoblasts in human bone marrow to TGF-Beta and calcitriol in vitro (1995) (0)
- The Role of Insulin-Like Growth Factor Binding Protein-5 in Bone (1997) (0)
- A calcium deficient diet impairs coupling of bone formation to bone resorption in young adults (1992) (0)
- Synthesis of 1,25 (OH)2D3 by isolated mammalian kidney cells (1980) (0)
- Use of a bone growth promoting composition (1991) (0)
- Molecular Mechanisms of Soft Tissue Regeneration and Bone Formation in Mice: Implications in Fracture Repair and Wound Healing in Humans (2000) (0)
- The renal metabolism of 25-hydroxyvitamin D3 in the rat: Regulation by 1,25-dihydroxyvitamin D3 (1983) (0)
- 91334007 The effects of estrone (Ogen) on spinal bone density of postmenopausal women (1992) (0)
- Elevation of serum calcitonin in idiopathic hypercalciuria (1979) (0)
- Role of Insulin-Like Growth Factor Binding Proteins and Their Proteases (1997) (0)
- Growth Hormone Axis-Independent Growth. A Case Report 438 (1998) (0)
- 187 A NEW SURGICAL TECHNIQUE THAT ENHANCES VECTOR APPLICATION FOR GENE THERAPY IN THE RAT FEMUR FRACTURE MODEL. (2004) (0)
- Growth factors: Potential treatment of osteoporosis (1995) (0)
- Differential activation of nuclear factor‐kappa B in healing tissue of poor healer SJL strain and good healer MRL strain: Implications in wound repair and regeneration (2006) (0)
- Development of a heterologous radioimmunoassay for canine osteocalcin (1994) (0)
- Growth hormone axis-independent growth (1998) (0)
- The Mitogenic Action of Fluoride on Human Bone Cells (1998) (0)
- Gene Therapy for Fracture Repair (2003) (0)
- AD Award Number : DAMD 17-011-0744 TITLE : Molecular Genetic Studies of Bone Mechanical Strain and of Pedigrees with Very High Bone Density PRINCIPAL INVESTIGATOR : (0)
This paper list is powered by the following services:
What Schools Are Affiliated With David J. Prof Baylink?
David J. Prof Baylink is affiliated with the following schools: