Daniel L. Alkon
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(Suggest an Edit or Addition)Daniel L. Alkon's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Accelerating the convergence of the back-propagation method (1988) (634)
- Insulin and the insulin receptor in experimental models of learning and memory. (2004) (466)
- Role of insulin and insulin receptor in learning and memory (2001) (464)
- Calcium-mediated reduction of ionic currents: a biophysical memory trace. (1984) (388)
- A spatial-temporal model of cell activation. (1988) (329)
- Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro. (1986) (311)
- Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice. (2004) (309)
- Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus. (1989) (277)
- PKC signaling deficits: a mechanistic hypothesis for the origins of Alzheimer's disease. (2007) (219)
- Classical conditioning reduces amplitude and duration of calcium-dependent afterhyperpolarization in rabbit hippocampal pyramidal cells. (1989) (218)
- Insulin receptor signaling in long-term memory consolidation following spatial learning. (2005) (194)
- Memory-specific temporal profiles of gene expression in the hippocampus (2002) (184)
- Associative Behavioral Modification in Hermissenda: Cellular Correlates (1980) (181)
- PKC ε Activation Prevents Synaptic Loss, Aβ Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice (2011) (178)
- Soluble beta-amyloid induction of Alzheimer's phenotype for human fibroblast K+ channels. (1994) (178)
- Reduction of two voltage-dependent K+ currents mediates retention of a learned association. (1985) (171)
- Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease (1998) (168)
- Memory storage and neural systems. (1989) (167)
- Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells. (1988) (167)
- Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory. (2004) (167)
- Thermal imaging of receptor-activated heat production in single cells. (1998) (163)
- Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair. (2008) (161)
- Intracellular Correlates of Acquisition and Long-Term Memory of Classical Conditioning in Purkinje Cell Dendrites in Slices of Rabbit Cerebellar Lobule HVI (1998) (159)
- Oxidation of Cholesterol by Amyloid Precursor Protein and β-Amyloid Peptide* (2005) (159)
- Gene expression profiles of heme oxygenase isoforms in the rat brain (2002) (152)
- Pairing-specific long-term depression of Purkinje cell excitatory postsynaptic potentials results from a classical conditioning procedure in the rabbit cerebellar slice. (1996) (152)
- Hippocampal lesions impair memory of short-delay conditioned eye blink in rabbits. (1989) (150)
- Carbonic anhydrase gating of attention: memory therapy and enhancement. (2002) (149)
- Calcium Responses in Fibroblasts from Asymptomatic Members of Alzheimer's Disease Families (1998) (144)
- A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC (2007) (139)
- Time domains of neuronal Ca2+ signaling and associative memory: steps through a calexcitin, ryanodine receptor, K+ channel cascade (1998) (138)
- Voltage-dependent calcium and potassium ion conductances: a contingency mechanism for an associative learning model. (1979) (135)
- Responses of Photoreceptors in Hermissenda (1972) (134)
- Posttranscriptional regulation of gene expression in learning by the neuronal ELAV-like mRNA-stabilizing proteins (2001) (133)
- Associative neural and behavioral change in Hermissenda: consequences of nervous system orientation for light and pairing specificity. (1982) (132)
- Rabbit cerebellar slice analysis of long-term depression and its role in classical conditioning (1993) (130)
- Dendritic excitability microzones and occluded long-term depression after classical conditioning of the rabbit's nictitating membrane response. (1997) (128)
- Associative Training of Hermissenda (1974) (122)
- Learning-specific differences in Purkinje-cell dendrites of lobule HVI (Lobulus simplex): intracellular recording in a rabbit cerebellar slice (1991) (121)
- Classical conditioning of Hermissenda: origin of a new response (1986) (121)
- Potassium channel dysfunction in fibroblasts identifies patients with Alzheimer disease. (1993) (116)
- Memory Traces in the Brain (1987) (111)
- Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains (2008) (109)
- Cellular mechanisms of learning, memory, and information storage. (1985) (105)
- C-kinase activation prolongs Ca2+-dependent inactivation of K+ currents. (1986) (100)
- AHP reductions in rabbit hippocampal neurons during conditioning correlate with acquisition of the learned response (1988) (99)
- Primary changes of voltage responses during retention of associative learning. (1982) (98)
- Change in a specific phosphoprotein band following associative learning in Hermissenda (1981) (95)
- ApoE4 and Aβ Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation (2015) (94)
- Bryostatin-1: pharmacology and therapeutic potential as a CNS drug. (2006) (93)
- Neuroprotective versus tumorigenic protein kinase C activators. (2009) (91)
- Spatial learning induced changes in expression of the ryanodine type II receptor in the rat hippocampus (2000) (91)
- Isolation of a G protein that is modified by learning and reduces potassium currents in Hermissenda. (1990) (90)
- Topography of Arc/Arg3.1 mRNA Expression in the Dorsal and Ventral Hippocampus Induced by Recent and Remote Spatial Memory Recall: Dissociation of CA3 and CA1 Activation (2005) (89)
- Protein kinase injection reduces voltage-dependent potassium currents. (1983) (88)
- Learning in a marine snail. (1983) (87)
- Specificity of molecular changes in neurons involved in memory storage (1990) (87)
- Arachidonic acid and diacylglycerol act synergistically to activate protein kinase C in vitro and in vivo. (1991) (85)
- Voltage-clamp analysis of the effects of classical conditioning on the hippocampus. (1991) (83)
- Dual effects of bryostatin-1 on spatial memory and depression. (2005) (83)
- Cellular Mechanisms of Conditioning and Behavioral Plasticity (1988) (81)
- Extinction of associative learning in Hermissenda: Behavior and neural correlates (1984) (80)
- Modulation of calcium-mediated inactivation of ionic currents by Ca2+/calmodulin-dependent protein kinase II. (1986) (79)
- Common mechanisms of Alzheimer's disease and ischemic stroke: the role of protein kinase C in the progression of age-related neurodegeneration. (2014) (77)
- Calcium-mediated decrease of a voltage-dependent potassium current. (1982) (77)
- Pharmacological enhancement of synaptic efficacy, spatial learning, and memory through carbonic anhydrase activation in rats. (2001) (77)
- Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts. (1998) (75)
- Calcium and cAMP as Synarchic Messengers (1983) (75)
- Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide. (2005) (75)
- Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration. (2005) (74)
- Sensory, interneuronal, and motor interactions within Hermissenda visual pathway. (1984) (73)
- Enhancement of synaptic potentials in rabbit CA1 pyramidal neurons following classical conditioning. (1988) (73)
- Light- and voltage-dependent increases of calcium ion concentration in molluscan photoreceptors. (1984) (72)
- Calcium responses in human fibroblasts: A diagnostic molecular profile for Alzheimer's disease (1996) (70)
- CELLULAR ANALYSIS OF A GASTROPOD (HERMISSENDA CRASSICORNIS) MODEL OF ASSOCIATIVE LEARNING (1980) (69)
- Ca2+-dependent protein kinase injection in a photoreceptor mimics biophysical effects of associative learning. (1984) (68)
- Plants Neither Possess nor Require Consciousness. (2019) (67)
- Voltage-dependent calcium and calcium-activated potassium currents of a molluscan photoreceptor. (1984) (67)
- MAP Kinase Signaling Cascade Dysfunction Specific to Alzheimer's Disease in Fibroblasts (2002) (66)
- Protein synthesis required for long-term memory is induced by PKC activation on days before associative learning. (2005) (66)
- The "memory kinases": roles of PKC isoforms in signal processing and memory formation. (2014) (65)
- Postischemic PKC activation rescues retrograde and anterograde long-term memory (2009) (65)
- Internal Ca 2 + mobilization is altered in fibroblasts from patients with Alzheimer disease (2005) (64)
- An internally controlled peripheral biomarker for Alzheimer’s disease: Erk1 and Erk2 responses to the inflammatory signal bradykinin (2006) (64)
- Pharmacological protection of synaptic function, spatial learning, and memory from transient hypoxia in rats. (2002) (63)
- A cellular model of Alzheimer's disease therapeutic efficacy: PKC activation reverses Aβ-induced biomarker abnormality on cultured fibroblasts (2009) (62)
- Bryostatin Effects on Cognitive Function and PKCɛ in Alzheimer’s Disease Phase IIa and Expanded Access Trials (2017) (62)
- Induced depressive behavior impairs learning and memory in rats (2004) (62)
- US-US conditioning of the rabbit’s nictitating membrane response: Emergence of a conditioned response without alpha conditioning (1990) (62)
- Responses of hair cells to statocyst rotation (1975) (61)
- Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury (2015) (60)
- Pharmacology of protein kinase C activators: cognition-enhancing and antidementic therapeutics. (2010) (60)
- Intersensory Interactions in Hermissenda (1973) (60)
- Reduction of β-Amyloid Levels by Novel Protein Kinase Cϵ Activators (2009) (60)
- Motile statocyst cilia transmit rather than directly transduce mechanical stimuli (1980) (60)
- Protein kinase C stimulates HuD‐mediated mRNA stability and protein expression of neurotrophic factors and enhances dendritic maturation of hippocampal neurons in culture (2012) (58)
- Gene expression profiles during long‐term memory consolidation (2001) (58)
- Hair Cell Generator Potentials (1973) (58)
- Apolipoprotein E3 (ApoE3) but Not ApoE4 Protects against Synaptic Loss through Increased Expression of Protein Kinase Cϵ (2012) (58)
- Theta rhythm of hippocampal CA1 neuron activity: gating by GABAergic synaptic depolarization. (2001) (58)
- Links between Alzheimer's disease and diabetes. (2006) (58)
- Differential Gender-Related Vulnerability to Depression Induction and Converging Antidepressant Responses in Rats (2006) (57)
- Regional Rat Brain Distribution of Heme Oxygenase-1 and Manganese Superoxide Dismutase mRNA: Relevance of Redox Homeostasis in the Aging Processes (2003) (57)
- Gene Expression Profiles in a Transgenic Animal Model of Fragile X Syndrome (2002) (57)
- Interaction of chemosensory, visual, and statocyst pathways in Hermissenda crassicornis (1978) (57)
- Secretion of Annexin II via Activation of Insulin Receptor and Insulin-like Growth Factor Receptor* (2003) (57)
- Physiological levels of β-amyloid increase tyrosine phosphorylation and cytosolic calcium (1995) (57)
- Primary neural substrates of learning and behavioral change (1984) (56)
- Neural organization predicts stimulus specificity for a retained associative behavioral change. (1980) (56)
- Memory reconsolidation in Hermissenda. (2003) (54)
- PKC activation during training restores mushroom spine synapses and memory in the aged rat (2013) (53)
- Hippocampal protein‐protein interactions in spatial memory (2004) (53)
- Bryostatin Improves Survival and Reduces Ischemic Brain Injury in Aged Rats After Acute Ischemic Stroke (2013) (52)
- Positive synaptic feedback in visual system of nudibranch mollusk Hermissenda crassicornis. (1982) (51)
- Peripheral biomarkers of Alzheimer's disease. (2015) (51)
- TNF‐α induced over‐expression of GFAP is associated with MAPKs (2000) (51)
- Mobilization of Calcium from Intracellular Stores, Potentiation of Neurotransmitter-Induced Calcium Transients, and Capacitative Calcium Entry by 4-Aminopyridine (2001) (50)
- Protein phosphorylation/dephosphorylation and the transient, voltage-dependent potassium conductance in Hermissenda crassicornis. (1983) (50)
- Changes of membrane currents during learning. (1984) (50)
- Cholesterol-enriched diet affects spatial learning and synaptic function in hippocampal synapses (2006) (48)
- Contraction of neuronal branching volume: an anatomic correlate of Pavlovian conditioning. (1990) (48)
- Conditioning-specific modification of the rabbit's unconditioned nictitating membrane response. (1995) (47)
- In vitro associative conditioning of Hermissenda: cumulative depolarization of type B photoreceptors and short-term associative behavioral changes. (1987) (47)
- Long-lasting depolarization and hyperpolarization in eye of Hermissenda. (1978) (47)
- Bryostatin Enhancement of Memory in Hermissenda (2006) (47)
- Sensory convergence on central visual neurons in Hermissenda. (1980) (47)
- Impairment of Hippocampal CA1 Heterosynaptic Transformation and Spatial Memory by β-Amyloid25–35 (2002) (46)
- Early enhancement of calcium currents by H-ras oncoproteins injected into Hermissenda neurons. (1990) (45)
- Calcium activates and inactivates a photoreceptor soma potassium current. (1985) (44)
- Open space swimming test to index antidepressant activity (2003) (44)
- ApoE isoforms differentially regulates cleavage and secretion of BDNF (2017) (44)
- Protection against β-Amyloid-induced Apoptosis by Peptides Interacting with β-Amyloid* (2007) (44)
- Protein kinase C redistribution within CA3 stratum oriens during acquisition of nictitating membrane conditioning in the rabbit. (1991) (44)
- Calexcitin interaction with neuronal ryanodine receptors. (1999) (44)
- Sequential modification of membrane currents with classical conditioning. (1988) (43)
- Alzheimer's Disease Cerebrospinal Fluid and Neuroimaging Biomarkers: Diagnostic Accuracy and Relationship to Drug Efficacy. (2015) (43)
- Synergistic activation of protein kinase C by arachidonic acid and diacylglycerols in vitro: generation of a stable membrane-bound, cofactor-independent state of protein kinase C activity. (1996) (43)
- Towards universal therapeutics for memory disorders. (2015) (43)
- Biophysical and behavioral correlates of memory storage, degradation, and reactivation. (1992) (42)
- Arachidonic acid and diacylglycerol act synergistically through protein kinase C to persistently enhance synaptic transmission in the hippocampus (1994) (42)
- A role for protein kinase C in associative learning. (1991) (42)
- Intracellular calcium signals are enhanced for days after Pavlovian conditioning. (2008) (41)
- Calexcitin: a signaling protein that binds calcium and GTP, inhibits potassium channels, and enhances membrane excitability. (1996) (40)
- Neural correlates of associative training in Hermissenda (1975) (40)
- Classical conditioning and protein kinase C activation regulate the same single potassium channel in Hermissenda crassicornis photoreceptors. (1992) (40)
- GABA‐Mediated Synaptic Interaction Between the Visual and Vestibular Pathways of Hermissenda (1993) (40)
- Bryostatin-1 Restores Hippocampal Synapses and Spatial Learning and Memory in Adult Fragile X Mice (2014) (39)
- Quantification and distribution of beta-secretase alternative splice variants in the rat and human brain. (2003) (39)
- A new approach to hand-written character recognition (1992) (39)
- PKC activator therapeutic for mild traumatic brain injury in mice (2011) (38)
- Time windows for effects of protein synthesis inhibitors on Pavlovian conditioning in Hermissenda: Behavioral aspects (2003) (38)
- Impairment of phosphatase 2A contributes to the prolonged MAP kinase phosphorylation in Alzheimer's disease fibroblasts (2003) (37)
- Early diagnostic accuracy and pathophysiologic relevance of an autopsy-confirmed Alzheimer's disease peripheral biomarker (2010) (36)
- Acquisition of conditioned associations in Hermissenda: additive effects of contiguity and the forward interstimulus interval. (1990) (35)
- Larval rearing, metamorphosis, growth and reproduction of the eolid nudibranch hermissenda crassicornis (eschscholtz, 1831) (gastropoda: opisthobranchia). (1978) (34)
- Ocular and extraocular responses of identifiable neurons in pedal ganglia of Hermissenda crassicornis. (1981) (34)
- Inositol trisphosphate regulation of photoreceptor membrane currents. (1986) (34)
- A Randomized, Double-Blind, Placebo-Controlled, Phase II Study Assessing Safety, Tolerability, and Efficacy of Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer’s Disease (2018) (33)
- Pavlovian conditioning of distinct components of Hermissenda's responses to rotation. (1990) (33)
- Ryanodine receptor modulation of in vitro associative learning in Hermissenda crassicornis (1999) (33)
- Associative learning potentiates protein kinase C activation in synaptosomes of the rabbit hippocampus. (1993) (33)
- Enhancement of long-term memory retention and short-term synaptic plasticity in cbl-b null mice. (2006) (32)
- Ca2+/Diacylglycerol‐Activated, Phospholipid‐Dependent Protein Kinase in the Hermissenda CNS (1986) (32)
- Molecular regulation of synaptogenesis during associative learning and memory (2015) (30)
- Cholinergic features of photoreceptor synapses in Hermissenda. (1979) (30)
- A method for measuring nanogram quantities of acetylcholine by pyrolysis-gas chromatography: the demonstration of acetylcholine in effluents from the rat phrenic nerve-diaphragm preparation. (1970) (30)
- Secondary Structure and Ca2+-induced Conformational Change of Calexcitin, a Learning-associated Protein* (1997) (30)
- GABA-induced potentiation of neuronal excitability occurs during contiguous pairings with intracellular calcium elevation (1991) (29)
- Activation of protein kinase C isozymes for the treatment of dementias. (2012) (29)
- Neural Mechanisms of Conditioning (2011) (28)
- Intracellular correlates of spatial memory acquisition in hippocampal slices: long-term disinhibition of CA1 pyramidal cells. (2001) (28)
- GABA-induced responses in Purkinje cell dendrites of the rabbit cerebellar slice (1992) (28)
- PKCε deficits in Alzheimer's disease brains and skin fibroblasts. (2014) (27)
- Emerging targets for the pharmacology of learning and memory. (2004) (27)
- Depolarization-induced effects of Ca2+-calmodulin-dependent protein kinase injection, in vivo, in single neurons of cat motor cortex (1984) (27)
- Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20. (1995) (26)
- Protein Kinase C Activators as Synaptogenic and Memory Therapeutics (2009) (26)
- Molecular Mechanisms of Memory and the Pathophysiology of Alzheimer's Disease (1994) (26)
- A common origin of voltage noise and generator potentials in statocyst hair cells (1979) (26)
- Induction of photoresponse by the hydrolysis of polyphosphoinositides in the Hermissenda type B photoreceptor. (1994) (26)
- Protein kinase C in the hippocampus is altered by spatial but not cued discriminations: A component task analysis (1995) (25)
- Evidence for nonsynaptic neuronal interaction. (1978) (25)
- The interstimulus interval and classical conditioning in the marine snail Hermissenda crassicornis (1989) (24)
- Reconstruction of ionic currents in a molluscan photoreceptor. (1993) (24)
- Biological plausibility of synaptic associative memory models (1994) (24)
- Age-dependent differential expression of BACE splice variants in brain regions of tg2576 mice (2005) (24)
- Gene expression profiles of apoptotic neurons. (2004) (23)
- Specific high molecular weight mRNAs induced by associative learning in Hermissenda. (1990) (22)
- Specific protein changes during memory acquisition and storage (1989) (22)
- Time-resolved imaging of protein kinase C activation during sea urchin egg fertilization. (1997) (22)
- Artificial neural networks - oscillations, chaos, and sequence processing (1993) (22)
- Protection against beta-amyloid-induced apoptosis by peptides interacting with beta-amyloid. (2007) (21)
- Complex responses to light of the nudibranch Hermissenda crassicornis (Gastropoda: opisthobranchia) (1980) (21)
- Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus. (2018) (21)
- Ionic conductance determinants of synaptic memory nets and their implications for Alzheimer's disease (1999) (21)
- Voltage noise from hair cells during mechanical stimulation (1977) (20)
- Signal transformation with pairing of sensory stimuli (1976) (20)
- Protein Kinase Cϵ (PKCϵ) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95* (2016) (20)
- PKC activators enhance GABAergic neurotransmission and paired-pulse facilitation in hippocampal CA1 pyramidal neurons (2014) (20)
- Behavioral effects of dietary cholesterol in rats tested in experimental models of mild stress and cognition tasks (2008) (19)
- Calcium-dependent potassium conductance in the photoresponse of a nudibranch mollusk (1981) (19)
- Translocation of protein kinase C‐βII in astrocytes requires organized actin cytoskeleton and is not accompanied by synchronous RACK1 relocation (2004) (19)
- Lateralization of membrane-associated protein kinase C in rat piriform cortex: Specific to operant training cues in the olfactory modality (1994) (19)
- Synergistic effects of chronic bryostatin-1 and alpha-tocopherol on spatial learning and memory in rats. (2008) (19)
- Impairment of hippocampal CA1 heterosynaptic transformation and spatial memory by beta-amyloid(25-35). (2002) (18)
- Long-term ethanol administration enhances age-dependent modulation of redox state in brain and peripheral organs of rat: protection by acetyl carnitine. (2002) (18)
- Bryostatin extends tPA time window to 6 h following middle cerebral artery occlusion in aged female rats. (2015) (18)
- Prolonged RNA changes in the Hermissenda eye induced by classical conditioning. (1988) (18)
- Functional switching of GABAergic synapses by ryanodine receptor activation. (2000) (18)
- Programs of Gene Expression During the Laying Down of Memory Formation as Revealed by DNA Microarrays (2002) (18)
- PKCε Promotes HuD-Mediated Neprilysin mRNA Stability and Enhances Neprilysin-Induced Aβ Degradation in Brain Neurons (2014) (18)
- Analysis of long-term cognitive-enhancing effects of bryostatin-1 on the rabbit (Oryctolagus cuniculus) nictitating membrane response (2008) (17)
- Neural modification by paired sensory stimuli (1976) (17)
- Activation of protein kinase C phosphorylation pathways: a role for storage of associative memory. (1991) (17)
- Protein kinase C pharmacology: perspectives on therapeutic potentials as antidementic and cognitive agents. (2006) (17)
- Effects of α2‐Adrenergic Agonists and Antagonists on Photoreceptor Membrane Currents (1987) (17)
- Orange Juice Classification with a Biologically Based Neural Network (1996) (16)
- Neurotransmitter synthesis in the nervous system of the mollusc Hermissenda. (1978) (16)
- Early regulation of membrane excitability by ras oncogene proteins. (1990) (15)
- Reply to Trewavas et al. and Calvo and Trewavas. (2020) (15)
- Protein kinase C isozymes: memory therapeutic potential. (2005) (15)
- Characterization of a GTP-binding protein implicated in both memory storage and interorganelle vesicle transport. (1994) (15)
- Pattern-recognition by an artificial network derived from biologic neuronal systems (1990) (15)
- Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice (2016) (15)
- A Biophysical Basis for Molluscan Associative Learning (1982) (15)
- Pavlovian conditioning-specific increases of the Ca2+- and GTP-binding protein, calexcitin in identified Hermissenda visual cells (2001) (15)
- Neuro-regeneration Therapeutic for Alzheimer's Dementia: Perspectives on Neurotrophic Activity. (2019) (15)
- Conditioning-Specific Biophysical Alterations in Rabbit Hippocampus (1988) (15)
- Protein kinase C mediates memory consolidation of taste avoidance conditioning in Lymnaea stagnalis (2014) (14)
- INDIVIDUAL VARIATION IN ASSOCIATIVE LEARNING OF THE NUDIBRANCH MOLLUSC HERMISSENDA CRASSICORNIS (1985) (14)
- A dual synaptic effect on hair cells in Hermissenda (1975) (14)
- Cerebral ischemia-induced difference in sensitivity to depression and potential therapeutics in rats (2013) (14)
- Associatively reduced withdrawal from shadows in Hermissenda: a direct behavioral analog of photoreceptor responses to brief light steps. (1987) (14)
- The Economy of Photoreceptor Function in a Primitive Nervous System (1976) (13)
- Acetylcholine: Release from Neural Tissue and Identification by Pyrolysis-Gas Chromatography (1969) (12)
- Cerebral hypoperfusion and amyloid-induced synergistic impairment of hippocampal CA1 synaptic efficacy and spatial memory in young adult rats. (2004) (12)
- Effects of 4-methylcatechol on spatial memory and depression (2008) (12)
- Protein kinase C: a nexus in the biochemical events that underlie associative learning. (1993) (12)
- Depressed or demented: common CNS drug targets?! (2002) (12)
- Calcium-regulated GTPase activity in the calcium-binding protein calexcitin. (2003) (12)
- Outgrowths fromHermissenda photoreceptor somata are associated with activation of protein kinase C (1990) (11)
- Inhibition of coactivator-associated arginine methyltransferase 1 modulates dendritic arborization and spine maturation of cultured hippocampal neurons (2017) (11)
- Identification of the PS1 Thr147Ile Variant in a Family with Very Early Onset Dementia and Expressive Aphasia (2015) (11)
- Impairment of Hippocampal CA 1 Heterosynaptic Transformation and Spatial Memory by-Amyloid 25 – 35 (2002) (11)
- Molecular mechanisms of associative memory and their clinical implications (1995) (11)
- Isolation of Protein Subpopulations Undergoing Protein-Protein Interactions* (2002) (11)
- Stress: perspectives on its impact on cognition and pharmacological treatment (2014) (11)
- The role of neurochemical modulation in learning (1986) (10)
- Optical sectioning of HRP-stained molluscan neurons (1982) (10)
- Associative learning in a network model of Hermissenda crassicornis (1993) (9)
- ABNORMAL CHOLESTEROL PROCESSING IN ALZHEIMER'S DISEASE PATIENT'S FIBROBLASTS (2003) (9)
- Biochemical mechanisms of memory storage. (1986) (9)
- Identification of faces obscured by noise: comparison of an artificial neural network with human observers (1997) (9)
- Implication of Novel Biochemical Property of β-Amyloid☆ (2000) (9)
- Computer Modeling of Associative Learning (1988) (8)
- Quantitative distribution of protein kinase C α, β, γ, and ϵ mRNAS in the hippocampus of control and nictitating membrane conditioned rabbits (1993) (8)
- Adduct formation in liquid chromatography-triple quadrupole mass spectrometric measurement of bryostatin 1. (2014) (8)
- Sensory interactions in the nudibranch mollusk Hermissenda crassicornis. (1974) (8)
- Differential expression of heme oxygenase isoforms in rat brain by endotoxin (LPS) (2003) (8)
- The release of acetylcholine from the innervated and denervated diaphragm. (1970) (8)
- Fibroblast aggregation rate converges with validated peripheral biomarkers for Alzheimer's disease. (2014) (8)
- Effects of age on susceptibility to the induction of depressive behavior and imipramine in rats (2008) (8)
- Inhibition of protein synthesis prolongs Ca2+-mediated reduction of K+ currents in molluscan neurons. (1987) (8)
- Calexcitin-like immunoreactivity in the pond snail Lymnaea stagnalis (2004) (8)
- G-protein effects on retrograde axonal transport (1993) (8)
- Imaging learning and memory: Classical conditioning (2001) (8)
- Gated informational transfer within the mammalian hippocampus: a new hypothesis (1993) (8)
- Two different biological configurations for long-term memory (2004) (8)
- Lead, learning, and calexcitin in Hermissenda. (1998) (7)
- Incorporation of Fluorescent Lipids into Living Rabbit Hippocampal and Cerebellar Slices (1994) (7)
- Spatiotemporal complexity of fibroblast networks screens for Alzheimer's disease. (2012) (7)
- Correlated receptor and motorneuron changes during retention of associative learning of Hermissenda crassicornis. (1982) (7)
- Associative learning in a network model of Hermissenda crassicornis (2004) (7)
- Changes of Membrane Currents and Calcium-Dependent Phosphorylation during Associative Learning (1986) (7)
- The nature of memory. (1989) (7)
- Associative learning in a network model of Hermissenda crassicornis (2004) (7)
- Mapping membrane potential transients in crayfish (Procambarus clarkii) optic lobe neuropils with voltage-sensitive dyes. (1999) (7)
- Molecular specificity of synaptic changes responsible for associative memory. (1998) (6)
- Effects of chronic bryostatin‐1 on treatment‐resistant depression in rats (2017) (6)
- Learning-induced activation of protein kinase C (1989) (6)
- Sequential changes of potassium currents in Hermissenda Type B photoreceptor during early stages of classical conditioning (1990) (6)
- Chronic bryostatin-1 rescues autistic and cognitive phenotypes in the fragile X mice (2020) (5)
- Effect of potassium conductance characteristics on pattern matching in a model of dendritic spines (1997) (5)
- Molecular mechanisms of memory and drug dependence. (1991) (5)
- "Either-or" two-slit interference: stable coherent propagation of individual photons through separate slits. (2001) (5)
- Cellular mechanisms of calcium elevation involved in long term memory (1998) (5)
- Molecular mechanisms of associative learning in mammal and mollusc. (1988) (5)
- Outgrowths from Hermissenda photoreceptor somata are associated with activation of protein kinase C. (1990) (5)
- An artificial neural network system for temporal-spatial sequence processing (1995) (5)
- Transforming growth factor beta induces a beta-responsive calcium fluxes in neurons. (1995) (5)
- Signaling Pathways Involved in Cognitive Enhancement (2015) (4)
- PKC and Insulin Pathways in Memory Storage: Targets for Synaptogenesis, Anti-apoptosis, and the Treatment of AD (2010) (4)
- Memory Enhancement by Bryostatin in Hermissenda (2004) (4)
- Learning and memory. FESN Study Group. (1991) (4)
- Bryostatin and its synthetic analog, picolog rescue dermal fibroblasts from prolonged stress and contribute to survival and rejuvenation of human skin equivalents (2018) (4)
- Confirmation of acetylcholine in perfusates of the stimulated vagus nerve by pyrolysis gas chromatography. (1970) (4)
- New developments in the search for a cure. (2011) (4)
- Parental deprivation. (1971) (4)
- Long-term synergistic regulation of ionic channels by C-kinase and Ca2+/CaM-type II kinase. (1987) (3)
- Biological plausibility of artificial neural networks: learning by non-Hebbian synapses (1993) (3)
- Dynamically stable associative learning: a neurobiologically based ANN and its applications (1992) (3)
- Training alone, not the tripeptide RGD, modulates calexcitin in Hermissenda. (2003) (3)
- Learning and memory (1991) (3)
- Dynamically stable associative learning (DYSTAL): a biologically motivated artificial neural network (1989) (3)
- Protein changes underlying long-term facilitation in Aplysia. (1989) (3)
- Protein kinase C substrate activators: potential as novel antidepressants (2005) (3)
- BRYOSTATIN-1 IMPROVES COGNITION AND DAILY LIVING TASKS IN MODERATE TO SEVERE ALZHEIMER’S DISEASE: PRELIMINARY REPORT OF A PHASE 2 STUDY (2017) (2)
- Background Illumination Effects upon in Vitro Conditioning in Hermissenda (2000) (2)
- Fluorophors formed from imidazoles. (1971) (2)
- Frontiers in CNS Drug Discovery (2017) (2)
- Regenerative changes of voltage-dependent Ca2+ and K+ currents encode a learned stimulus association. (1982) (2)
- PKC epsilon Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95 (2016) (2)
- Use of CD and FT-IR to determine the secondary structure of purified proteins in the low-microgram range. (1998) (2)
- REDUCTION OF BETA-AMYLOID LEVELS BY NOVEL PKC EPSILON ACTIVATORS (2009) (2)
- Self Organizing Neural Network Character Recognition Using Adaptive Ltering and Feature Extraction (1992) (2)
- Role of phospholipid metabolic products in associative learning (1989) (2)
- BEHAVIORAL, ELECTROPHYSIOLOGICAL, AND MORPHOLOGICAL INVESTIGATIONS OF STATOCYST FUNCTION IN THE NUDIBRANCH MOLLUSC HERMISSENDA CRASSICORNIS (1986) (2)
- Regulation of Ca2+ stores in glial cells (2003) (2)
- Potassium Channels and Calcium Release: Pathophysiological and Diagnostic Implications for Alzheimer's Disease (1996) (2)
- Corrigendum to “Dual effects of bryostatin-1 on spatial memory and depression” [Eur. J. Pharmacol. 512 (2005) 43–51] (2005) (2)
- Functional Characterization of the Squid Calexcitin-2, a Calcium and GTP-binding Protein (2000) (2)
- 10 Cellular Analysis of Gastropod Learning (1987) (2)
- Protein phosphorylation and associative learning in Hermissenda. (1986) (2)
- Voltage noise power spectra reflect ciliary movement frequencies in statocyst hair cells (1982) (1)
- Biophysics of memory. (1990) (1)
- Protein kinase Credistribution within CA3stratum oriens during acquisition ofnictitating membraneconditioning intherabbit (1991) (1)
- Bryostatin Placebo-Controlled Trials Indicate Cognitive Restoration Above Baseline for Advanced Alzheimer’s Disease in the Absence of Memantine (2022) (1)
- Neural Correlates of Memory Storage (1992) (1)
- POTASSIUM CHANNELS AND INTERNAL CALCIUM RELEASE: RELEVANCE FOR MEMORY STORAGE AND ALZHEIMER'S DISEASE (1995) (1)
- Processing temporal sequences with a biologically-based artificial network (1993) (1)
- Heterogenous Distribution of Fluorescent Phorbol Ester Signal in Living Sea Urchin Embryos. (1992) (1)
- Persistent Inactivation of Potassium Currents by Elevation of Intracellular Calcium (1986) (1)
- Conservation of Cellular Mechanisms for Models of Learning and Memory (1988) (1)
- Alzheimer and ,3-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp2O (2005) (1)
- Potassium Channels and Calcium Release (1997) (1)
- Different ionic conductances are modulated during the late receptor potential and the prolonged depolarizing afterpotential in Hermissenda type A photoreceptors (1993) (1)
- Implication of novel biochemical property of beta-amyloid. (2000) (1)
- Effects of noise in training patterns on the diluted Hopfield neural network (1993) (1)
- Modulation of calcium current and late potassium currents by intrasomatic injection of calcium calmodulin dependent kinase in hermissenda giant neurons (1984) (1)
- Tea- and bradykinin(BK)-induced calcium responses in Alzheimer's disease (AD) and control fibroblasts: A ratio index with diagnostic capability (2000) (0)
- Contraction ofneuronal branching volume: Ananatomic correlate ofPavlovian conditioning (1990) (0)
- HermissendaIntermediate Phase of Memory in - Dependent and mRNA Synthesis - Protein Synthesis (2015) (0)
- Personalized E-Learning Systems (2020) (0)
- Adenosine A1 receptor antagonists for treatment of memory disorders and learning hypoxiebedingten (2002) (0)
- Cellular Mechanisms of Classical Conditioning (2002) (0)
- Bryostatin-1 Restores Blood Brain Barrier Integrity following Blast-Induced Traumatic Brain Injury (2014) (0)
- Identification of ion channel regulating proteins by patch-clamp analysis. (1998) (0)
- Quantitative distribution of protein kinase C alpha, beta, gamma, and epsilon mRNAs in the hippocampus of control and nictitating membrane conditioned rabbits. (1993) (0)
- New implications of memory mechanisms for Alzheimer's disease. (1993) (0)
- P.4.06 Behavioral modifications induced by dietary cholesterol in rats (2005) (0)
- Peripheral diagnostic procedures for screening Alzheimer's disease using amyloid beta and intercellular communication (2012) (0)
- Membrane Channels, Conditioning-Induced Changes (1988) (0)
- 615 A laboratory diagnosis of alzheimer's disease with patch-clamp and CA2+-imaging techniques (1993) (0)
- Microcalorimetric study of metabotropic receptor signal transduction in living cells (1997) (0)
- SIGNIFICANT COGNITIVE IMPROVEMENT WITH BRYOSTATIN FOR ADVANCED ALZHEIMER’S PATIENTS IN THE ABSENCE OF MEMANTINE (2018) (0)
- VOLTAGE-DEPENDENT POTASSIUM CURRENT (2005) (0)
- Effects of alpha 2-adrenergic agonists and antagonists on photoreceptor membrane currents. (1987) (0)
- Inhibition of protein synthesis prolongs Ca 2-mediated reduction of K + currents in molluscan neurons ( Hermissenda crasswornis / memory / protein kinase C / Ca 2 +-activated phospborylation / anisomycin ) (0)
- P43 EFFECTS OF DIETARY CHOLESTEROL ON DEPRESSION IN RATS (2004) (0)
- Specific alterations of alzheimer's disease of the proportion of erk1 / erk2 phosphorilation - specific molecular biomarkers of alzheimer's disease (adsmb). (2006) (0)
- Reconstruction of photoreceptor responses in nudibranch mollusc, Hermissenda crassicorni based on isolated ionic currents (1989) (0)
- GABA-induced calcium elevation in the terminal branches of type B photoreceptors (1991) (0)
- Computational Hermissenda Photoarray Model (1994) (0)
- A MODEL OF ASSOCIATIVE LEARNING IN J-E- A CRASSICORN IS: SENSITIVITIES TO TEMPORAL RELATIONSHIPS OF STIMULI (1991) (0)
- Procedures for identifying treatments for Alzheimer's disease (2006) (0)
- Alzheimer's disease-specific changes in the Erkheimer specific molecular biomarker (adsmb) (2006) (0)
- Links between Alzheimer's disease and diabetes. (2006) (0)
- Reviewer Acknowledgments (2009) (0)
- Self-Organization of Cortical Information Processing (2018) (0)
- NEURAL NETWORK WITH WEIGHT ADJUSTMENT BASED ON PRIOR HISTORY OF INPUT SIGNALS (2017) (0)
- Method of monitoring the progression of Alzheimer's disease by measuring a biomarker (2006) (0)
- Production Rules (2014) (0)
- Ionic current model on the type B photoreceptor in hermissenda (1987) (0)
- Un conjugue comprenant un compose cholesterol lie a la tetracycline (2003) (0)
- CALEXCITIN-LIKE IMMIJNOREACTIVITY IN THE POND SNAIL LYMNAEA STAGNALIS (2004) (0)
- P2-390: A combination strategy for the Alzheimer's disease treatment (2008) (0)
- A quantum basis for the relativistic doppler effect for light (2000) (0)
- Neural principles of associative learning: Reconstruction of ionic currents in the type B photoreceptor (1988) (0)
- Enzymatic properties of beta-amyloid (1999) (0)
- Enhancement of synaptic potentials in rabbit CAl pyramidal neurons following classical conditioning (learning and memory/hippocampus/brain slice) (2016) (0)
- Cellular calcium responce for diagnosis of alzheimer's disease (2001) (0)
- Tumor Necrosis Factor‐α (TNF‐α), Interferon‐γ, and Interleukin‐6 but Not TNF‐β Induce Differentiation of Neuroblastoma Cells: The Role of Nitric Oxide (1994) (0)
- A direct evidence that protein kinase C exists in the neuron of (1991) (0)
- PKCε Activation Restores Loss of PKCε, Manganese Superoxide Dismutase, Vascular Endothelial Growth Factor, and Microvessels in Aged and Alzheimer’s Disease Hippocampus (2022) (0)
- Therapeutic effects of bryostatins, bryologists and related substances in impaired memory induced head trauma and brain injury (2008) (0)
- Memory-associated changes in the distribution of brain protein kinase C as visualized by quantitative autoradiography of 3H-phorbol-12,13-dibutyraitne fresh frozen cryosections (1992) (0)
- Evidence of significant cognitive improvement over baseline in advanced Alzheimer’s disease (AD) patients: A regenerative therapeutic strategy (2021) (0)
- ApoE isoforms differentially regulates cleavage and secretion of BDNF (2017) (0)
- Therapeutic effects of bryostatins on memory impairment induced ischemia / stroke and brain injuries (2008) (0)
- Neuroscience calendar (1988) (0)
- P2-124 PKC and ELAV-like mRNA binding proteins: a new cascade for memory trace formation and Alzheimer's disease (2004) (0)
- Whole cell clamp study of gabaergic responses of type B photoreceptors in (1991) (0)
- Alzheimer's phenotype K+ channel dysfunction in human skin fibroblasts caused by β-amyloid protein (1994) (0)
- GTP-binding proteins and potassium channels involved in synaptic plasticity and learning (2008) (0)
- Kit for diagnosing Alzheimer's Disease (2006) (0)
- Morphometric imaging biomarker identifies Alzheimer’s disease even among mixed dementia patients (2022) (0)
- Synaptic transmission and neuronal interaction (1975) (0)
- Synaptic mechanisms of associative memory storage in biological and artificial networks (1992) (0)
- Profile genomic markers induced by a stimulus that mark Alzheimer's disease (2009) (0)
- THE PHYSICAL REALITY OF MEMORY (1989) (0)
- CHANNEL MODEL OF SECOND MESSENGER MEDIATED TRANSFORMATION OF GABA INDUCED CURRENTS (2008) (0)
- PCK alfa recruitment of neural Elav proteins: implication for mRNA stability and translation (2005) (0)
- Cellular memory in an invertebrate (1992) (0)
- Elav-Like Proteins And Protein Kinase C: A New Cascade For Memory Trace Formation And Alzheimer's Disease? (2005) (0)
- What can the physician offer the patient presenting with dementia? (2011) (0)
- Wave-Particle Duality and the Perception of Spatial-Temporal Coherence (1999) (0)
- Running title : Rescuing synapses and spatial memory in young fragile X mice (2016) (0)
- Neural correlates of memory storage. The role of ion channels. (1992) (0)
- Calcium dependent potassium conductance in the photo response of a nudibranch mollusk hermissenda crassicornis (1981) (0)
- REPLICATION TRIAL TO CONFIRM REVERSAL OF COGNITIVE DECLINE WITH BRYOSTATIN FOR ADVANCED ALZHEIMER’S PATIENTS IN THE ABSENCE OF MEMANTINE (2019) (0)
- DETWILER AND ALKON Hair Cell Interactions in Statocyst of Hermissenda 619 Recently Alkon and Bak (2003) (0)
- Imaging of intracellular translocation of protein kinase C (1994) (0)
- Contribution of GABA to visual-vestibular interaction in Hermissenda (1992) (0)
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