Dirk L. Brutsaert
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(Suggest an Edit or Addition)Dirk L. Brutsaert's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. (2007) (2589)
- New concepts in diastolic dysfunction and diastolic heart failure: Part I: diagnosis, prognosis, and measurements of diastolic function. (2002) (1207)
- EuroHeart Failure Survey II (EHFS II): a survey on hospitalized acute heart failure patients: description of population. (2006) (1170)
- New concepts in diastolic dysfunction and diastolic heart failure: Part II: causal mechanisms and treatment. (2002) (916)
- Personality as independent predictor of long-term mortality in patients with coronary heart disease (1996) (676)
- How to diagnose diastolic heart failure (1998) (671)
- Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity. (2003) (628)
- Triple control of relaxation: implications in cardiac disease. (1984) (478)
- Inadequate response to treatment in coronary heart disease : adverse effects of type D personality and younger age on 5-year prognosis and quality of life. (2000) (432)
- Personality, disease severity, and the risk of long-term cardiac events in patients with a decreased ejection fraction after myocardial infarction. (1998) (411)
- Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology (2011) (380)
- Advanced chronic heart failure: A position statement from the Study Group on Advanced Heart Failure of the Heart Failure Association of the European Society of Cardiology (2007) (374)
- Relaxation and diastole of the heart. (1989) (353)
- Diastolic failure: pathophysiology and therapeutic implications. (1993) (335)
- Personality and Mortality After Myocardial Infarction (1995) (323)
- Dual control of relaxation. Its role in the ventricular function in the mammalian heart. (1980) (307)
- Myocardial contractile response to nitric oxide and cGMP. (1996) (302)
- Effects of Damaging the Endocardial Surface on the Mechanical Performance of Isolated Cardiac Muscle (1988) (270)
- Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure (2010) (239)
- Nonuniformity: a physiologic modulator of contraction and relaxation of the normal heart. (1987) (191)
- Analysis of relaxation in the evaluation of ventricular function of the heart. (1985) (186)
- The continuous heart failure spectrum: moving beyond an ejection fraction classification. (2019) (170)
- Gender related differences in patients presenting with acute heart failure. Results from EuroHeart Failure Survey II (2008) (158)
- Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology (2019) (155)
- Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association–European Society of Cardiology (2018) (155)
- Cytokines and immune activation in systolic heart failure: the role of Type D personality (2003) (152)
- Nonuniformity of endothelial constitutive nitric oxide synthase distribution in cardiac endothelium. (1998) (151)
- Combined endurance/resistance training reduces plasma TNF-alpha receptor levels in patients with chronic heart failure and coronary artery disease. (2002) (143)
- Reducing Emotional Distress Improves Prognosis in Coronary Heart Disease: 9-Year Mortality in a Clinical Trial of Rehabilitation (2001) (141)
- Relaxation of ventricular cardiac muscle. (1978) (138)
- Cardiac endothelium and myocardial function. (1998) (127)
- The endocardial endothelium. (1992) (127)
- Systolic and Diastolic Heart Failure Are Overlapping Phenotypes Within the Heart Failure Spectrum (2011) (119)
- Cardiac endothelium-myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction. (2015) (116)
- Neuregulin-1 Induces a Negative Inotropic Effect in Cardiac Muscle: Role of Nitric Oxide Synthase (2004) (107)
- Force‐Velocity‐Length‐Time Relations of the Contractile Elements in Heart Muscle of the Cat (1969) (103)
- Cardiac Remodeling: Endothelial Cells Have More to Say Than Just NO (2018) (103)
- The innate immune system in chronic cardiomyopathy: a European Society of Cardiology (ESC) scientific statement from the Working Group on Myocardial Function of the ESC (2018) (101)
- The autonomic nervous system as a therapeutic target in heart failure: a scientific position statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology (2017) (100)
- Endothelial dysfunction: a pathophysiologic factor in heart failure with preserved ejection fraction. (2012) (91)
- Treatments targeting inotropy. (2018) (91)
- Onset of Mechanical Activation of Mammalian Heart Muscle in Calcium‐ and Strontium‐Containing Solutions (1974) (91)
- Effects of Altered Loading on Contractile Events in Isolated Cat Papillary Muscle (1969) (90)
- Combined endurance/resistance training reduces plasma TNF-alpha receptor levels in patients with chronic heart failure and coronary artery disease (2002) (90)
- Atriopeptin III Induces Early Relaxation of Isolated Mammalian Papillary Muscle (1988) (88)
- Effect of dysfunctional vascular endothelium on myocardial performance in isolated papillary muscles. (1993) (87)
- Systolic and diastolic heart failure: Different phenotypes of the same disease? (2007) (84)
- Global left atrial failure in heart failure (2016) (84)
- An integrative translational approach to study heart failure with preserved ejection fraction: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology (2018) (81)
- Diastolic dysfunction in heart failure. (1997) (79)
- Nature of load dependence of relaxation in cardiac muscle. (1979) (79)
- Myocardial mechanics in ppillary muscles of the rat and cat. (1969) (73)
- The cardiac endothelium: functional morphology, development, and physiology. (1996) (72)
- Force velocity relations of single cardiac muscle cells: calcium dependency (1977) (71)
- Diastolic heart failure: a myth. (2006) (70)
- Enhancing emotional well-being by comprehensive rehabilitation in patients with coronary heart disease. (1995) (69)
- Cardiac muscle mechanics in the evaluation of myocardial contractility and pump function: problems, concepts, and directions. (1973) (69)
- Effects of abrupt load alterations on force—velocity—length and time relations during isotonic contractions of heart muscle: load clamping (1971) (67)
- Influence of caffeine on force development and force-frequency relations in cat and rat heart muscle. (1974) (64)
- Myocardial performance is modulated by interaction of cardiac endothelium derived nitric oxide and prostaglandins. (1995) (64)
- Does endocardial endothelium mediate positive inotropic response to angiotensin I and angiotensin II? (1990) (59)
- Influence of loading patterns on peak length-tension relation and on relaxation in cardiac muscle. (1989) (55)
- Cardiac dysfunction in heart failure: the cardiologist's love affair with time. (2006) (55)
- Ventricular function: Evaluation of myocardial contractility in health and disease (1970) (54)
- Loading and performance of the heart as muscle and pump. (1977) (53)
- Activation of Cardiac Endothelium as a Compensatory Component in Endotoxin-Induced Cardiomyopathy: Role of Endothelin, Prostaglandins, and Nitric Oxide (2001) (52)
- DIASTOLIC FAILURE - PATHOPHYSIOLOGY AND THERAPEUTIC IMPLICATIONS (VOL 22, PG 318, 1993) (1993) (51)
- The endocardium. (1989) (49)
- Load‐Insensitive Relaxation Caused by Hypoxia in Mammalian Cardiac Muscle (1981) (48)
- Diagnosing primary diastolic heart failure. (2000) (48)
- Eosinophils from hypereosinophilic patients damage endocardium of isolated feline heart muscle preparations. (1990) (47)
- Pathophysiology of Heart Failure: Back to Basics (2013) (47)
- Endothelin-mediated positive inotropic effect induced by reactive oxygen species in isolated cardiac muscle. (1995) (47)
- The heart failure spectrum: time for a phenotype-oriented approach. (2009) (45)
- Systems-Based Approaches to Cardiovascular Biomarker Discovery (2012) (43)
- Diastolic heart failure: a separate disease or selection bias? (2007) (43)
- Determinants of force decline during relaxation in isolated cardiac muscle. (1989) (43)
- Improvement of endocardial and vascular endothelial function on myocardial performance by captopril treatment in postinfarct rat hearts. (1999) (39)
- Myocardial inotropic responses to aggregating platelets and modulation by the endocardium. (1989) (38)
- Myocardial stiffness during hypoxic and reoxygenation contracture. (1980) (38)
- Loading determinants of relaxation in cat papillary muscle. (1982) (37)
- Positive inotropic effect of nitric oxide in myocardium. (1995) (36)
- Endocardium modulates myocardial inotropic response to 5-hydroxytryptamine. (1989) (33)
- Pulmonary hypertension and right heart failure in heart failure with preserved left ventricular ejection fraction: pathophysiology and natural history (2012) (33)
- Endocardial endothelium mediates positive inotropic response to alpha 1-adrenoceptor agonist in mammalian heart. (1990) (32)
- Mechanics of K(+)-induced isotonic and isometric contractions in isolated canine coronary microarteries. (1990) (31)
- An analysis of the mechanical capabilities of heart muscle during hypoxia. (1973) (31)
- Intracavitary ultrasound impairs left ventricular performance: presumed role of endocardial endothelium. (1992) (29)
- Mechanical Properties of Resting and Active Isolated Coronary Arteries (1984) (29)
- Inotropic effects of amrinone and milrinone on contraction and relaxation of isolated cardiac muscle. (1986) (29)
- Tetanic contraction in mammalian cardiac muscle. (1971) (28)
- Relaxation abnormalities in cardiac hypertrophy. (1982) (28)
- End‐Systolic Pressure‐Volume Relation Estimated from Physiologically Loaded Cat Papillary Muscle Contractions (1980) (28)
- Load clamp analysis of maximal force potential of mammalian cardiac muscle. (1977) (28)
- Role of endocardial endothelium in positive inotropic action of vasopressin. (1990) (26)
- Effects of Various Inotropic Interventions on the Dynamic Properties of the Contractile Elements in Heart Muscle of the Cat (1970) (25)
- P176 Cardiac safety guidelines for the adjuvant use of trastuzumab (Herceptin®) in HER2-positive early breast cancer (2007) (25)
- Diagnostic significance of impaired LV systolic relaxation in heart failure. (1995) (25)
- Whole cell membrane currents in cultured pig endocardial endothelial cells. (1995) (25)
- Nature of force-velocity relation in heart muscle. (1971) (24)
- Uniform sarcomere behaviour during twitch of intact single cardiac cells. (1984) (23)
- Expansion of the left atrial appendage is a distinctive cross-sectional echocardiographic feature of congenital defect of the pericardium. (1983) (23)
- The future of pleiotropic therapy in heart failure. Lessons from the benefits of exercise training on endothelial function (2017) (22)
- Distribution and role of Na(+)/K(+) ATPase in endocardial endothelium. (2001) (22)
- Contractility in Mammalian Heart Muscle: CALCIUM AND OSMOLALITY (1975) (22)
- Diastolic heart failure: perception of the syndrome and scope of the problem. (2006) (21)
- Post-reextension force decay of relaxing cardiac muscle. (1987) (21)
- Role of endocardium in cardiac overloading and failure. (1990) (20)
- Sarcomere distribution patterns in single cardiac cells. (1981) (20)
- Three-step yielding of load-clamped mammalian cardiac muscle (1976) (20)
- Chapter 49 Acute heart failure: epidemiology, classification, and pathophysiology (2010) (20)
- Reappraisal of the multicellular preparation for the in vitro physiopharmacological evaluation of myocardial performance. (1998) (19)
- Physiological Loading of Isolated Mammalian Cardiac Muscle (1976) (18)
- Influence of abrupt pressure increments on left ventricular relaxation (1980) (18)
- Positive Inotropic and Vasodilating Effects of Amrinone and Milrinone in Isolated Canine Heart (1987) (18)
- Morphoregulatory interactions of endocardial endothelium and extracellular material in the heart. (1995) (17)
- Ventricular function. Is the total more than the sum of the parts? (1991) (16)
- Mechanical properties of papillary muscle in cardiac failure: importance of pathogenesis and of ventricle of origin. (1989) (16)
- Infrared-emitting diode and optic fibers for underwater force measurement in heart muscle. (1971) (16)
- Endocardial function in pacing-induced heart failure in the dog. (1993) (16)
- Physiopharmacological evaluation of myocardial performance: how to study modulation by cardiac endothelium and related humoral factors? (1998) (16)
- Alteration of Left Ventricular Endocardial Function by Intracavitary High‐Power Ultrasound Interacts With Volume, Inotropic State, and &agr;1‐Adrenergic Stimulation (1993) (15)
- Differences in structure between endocardial and vascular endothelium (1991) (15)
- Dilated Cardiomyopathy: Changing PathophysiologicaI Concepts and Mechanisms of Dysfunction (1999) (15)
- Endocardial endothelium in the rat: junctional organization and permeability (1994) (14)
- Physiological Loading of Isolated Feline Cardiac Muscle: The Interaction between Muscle Contraction and Vascular Impedance in the Production of Pressure and Flow Waves (1979) (14)
- Influence of different stimulation frequencies on the cardiac output at rest and during moderate exercise in dogs with chronic atrioventricular heart block. (1965) (13)
- Load-dependence of physiologically relaxing cardiac muscle. (1980) (13)
- Endocardial endothelial dysfunction and heart failure. (1996) (13)
- Endocardial control of myocardial performance. (1988) (12)
- Endocardial endothelial dysfunctionand heart failure (1996) (12)
- Dilated Cardiomyopathy: Changing PathophysiologicaI Concepts and Mechanisms of Dysfunction (1985) (12)
- Endocardial endothelium in the rat: cell shape and organization of the cytoskeleton (1993) (11)
- Regulation of left ventricular pressure fall. (1990) (11)
- V max : its relation to contractility of heart muscle. (1972) (11)
- Mechanisms of relaxation in the heart as a muscle and pump. (1978) (10)
- Ultrasound as a novel method for selective damage of endocardial endothelium. (1991) (10)
- Is relaxation really impaired in cardiac failure? (1983) (9)
- Diastolic dysfunction in post-cardiac surgical management. (1993) (9)
- Nonuniformity of contraction and relaxation of mammalian cardiac muscle. (1984) (8)
- Influence of the breathing mode on the time course and amplitude of the cyclic inter-atrial pressure reversal in postoperative coronary bypass surgery patients. (1993) (7)
- The early onset of maximum velocity of shortening in heart muscle of the cat (2004) (7)
- Decreased myocardial contractility after damage to endocardial endothelium is not merely caused by loss of endothelin production. (1995) (7)
- Endocardial Endothelium: Control of Cardiac Performance (1995) (7)
- Mechanisms of hypoxia-induced decrease of load dependence of relaxation in cat papillary muscle (1984) (7)
- Contraction and relaxation of the heart as muscle and pump. (1979) (6)
- Comments on "How to quantify pump function of the heart". (1980) (6)
- Pacemaker endocarditis: contribution of two-dimensional echocardiography. (1984) (6)
- Maximal force potential of tetanized mammalian smooth muscle. (1982) (5)
- Force-velocity-length relationship in heart muscle: Lack of time-independence during twitch contractions of frog ventricle strips with caffeine (1974) (5)
- Letter by Brutsaert and De Keulenaer Regarding Article, "Effects of Sildenafil on Ventricular and Vascular Function in Heart Failure With Preserved Ejection Fraction". (2015) (5)
- Mechanisms of endocardial endothelium modulation of myocardial performance. (1993) (5)
- Load Dependence of Relaxation (1987) (5)
- Time course of mechanical activation in cardiac muscle. (1973) (5)
- Vascular-derived myocardial contractile factor: positive myocardial inotropic substance released from medial layer of the canine aorta. (1996) (4)
- Diastolic heart function and dysfunction. (1999) (4)
- Is stiffness increased during ischemia? (1989) (4)
- Relaxation of tetanized canine tracheal smooth muscle (1981) (4)
- A reappraisal of force-velocity measurements in isolated heart muscle preparations. (1973) (3)
- Endocardial endothelial dysfunction (1995) (3)
- Contractility in Mammalian Heart Muscle (1975) (3)
- Treatments targeting inotropy A position paper of the Committees on Translational Research and Acute Heart Failure of the Heart Failure Association of the European Society of Cardiology (2019) (3)
- Pathogenesis of heart failure. Changing conceptual paradigms. (1998) (3)
- Treatment of advanced chronic heart failure with normal left ventricular ejection fraction. Response to the letter by Dr. Martinez‐Selles (2007) (3)
- Mechanisms of endocardial endothelium modulation of myocardial performance. (1995) (3)
- Endocardial endothelium modulates inotropic responses of subjacent myocardium (1991) (3)
- The indispensable role of cardiac endothelium in the structure and function of the heart. (2003) (3)
- Effects of AQA39 on contractile performance of isolated mammalian ventricular myocardium. (1984) (3)
- Molecular Mechanisms of Diastolic Dysfunction (2008) (3)
- Role of Endocardial Endothelium in the Positive Inotropic Effect of Cholic Acid in Isolated Myocardium (1992) (3)
- Relaxation of tetanised smooth muscle of canine saphenous vein. (1981) (3)
- The heart as an integrated muscle and pump system: triple control and subdivision of the cardiac cycle. (1984) (3)
- Mechanisms of load independence of relaxation during hypoxia in mammalian cardiac muscle (1981) (3)
- Effect of temperature on the mechanical behaviour of single skinned cardiac cells (1981) (2)
- [The effect of a cardiac rehabilitation program on return to work]. (1989) (2)
- Positive Inotropic Effect of Bradykinin: Role of Cardiac Endothelium, Nitric Oxide, Prostaglandins and Endothelin (1998) (2)
- Nonuniformity: an important physiological modulator of the contractile performance of the normal heart. (1985) (2)
- Positive inotropic effect of Streptococcus faecalis in isolated cardiac muscle. (1994) (2)
- Physiologic aspects of relaxation of the myocardium. (1990) (2)
- A.131 Role of the endocardial endothelium in the negative inotropic effects of thiopentone: possible mechanisms (1996) (2)
- The positive inotropic effects of hydrostatic pressure are buffered by the endocardial endothelium via prostaglandins (2000) (2)
- The endothelium and cardiocirculatory function, Part I. Introduction. (1996) (2)
- Physiological pump loading of isolated cardiac muscle. (1976) (2)
- Comments on "Role of glycolytic products in damage to ischemic myocardium". (1986) (2)
- Endocardial Endothelial Modulation of Myocardial Contraction (1996) (2)
- Heart Failure with Preserved Ejection Fraction (2008) (2)
- Analysis of the instantaneous force-velocity-length-time relations of the contractile elements of the myocardium. (1969) (1)
- Left ventricular function in athletes: analysis of relaxation (1986) (1)
- Automatic Evaluation of Left Ventricular Contour from Two-Dimensional Echocardiography (1983) (1)
- Concerning contraction and relaxation of the heart. (1979) (1)
- Effects of ryanodine on relaxation in isolated myocardium from different animal species (1988) (1)
- The early occurrence of maximum velocity of shortening in heart muscle. (1970) (1)
- Chronic pretreatment with amrinone or milrinone induces no tachyphylaxis in mammalian cardiac muscle (1986) (1)
- The Force‐Velocity‐Length‐Time Interrelation of Cardiac Muscle (2008) (1)
- Normal Physiology and Pathophysiology of Left Ventricular Diastole (2008) (1)
- Endocardial endothelial cell communication (1998) (1)
- Muscle and Pump Function of the Mammalian Heart (1976) (1)
- Impressive amelioration of clinical (NYHA class) and echocardiographic parameters in heart failure patients treated with amiodarone and carvedilol. (2001) (1)
- Urgent need to reorganize heart failure management: from paradoxes to heart failure clinics (2005) (1)
- Voltage clamping of isolated single cardiac myocytes. (1981) (1)
- Pathophysiology and Clinical Impact of Diastolic Heart Failure (2007) (1)
- Effects of osmolality on hypoxic myocardium. (1974) (1)
- Proceedings: Osmolality and myocardial function. (1974) (1)
- [The double control system of heart relaxation]. (1980) (1)
- Cardiac endothelium and myocardial function 1 (1998) (1)
- Chapter 9 Chronic heart failure with preserved ejection fraction (2008) (0)
- Controversial Methodological Aspects (1972) (0)
- [Influence of hypertonic saline solutions on pulmonary circulation]. (1960) (0)
- RELAXATION OF TETANIZED TRACHEAL SMOOTH MUSCLE (1981) (0)
- Volume Contents (2005) (0)
- Progress in cardiovascular diseases: introduction. (1997) (0)
- Letter to the Editor (2001) (0)
- The endothelium in clinical practice: Source and target of novel therapies edited by Gabor M. Rubanyi and Victor J. Dzau Marcel Dekker, Inc., New York (1997) 551 pages, illustrated, $195.00 ISBN: 0–8247–9809–0 (1998) (0)
- The Heart as a Muscle and a Pump: Ventricular Function of the Heart in Ischemic Heart Disease (1983) (0)
- Mechanical performance of single cardiac cells (film) (1978) (0)
- Role of the endocardium in the inotropic action of UD-CG-212 CL. (1991) (0)
- Point of View Ventricular Function Is the Total More Than the Sum of the Parts? (2005) (0)
- The influence of viscous elements on myocardial contractility. (1969) (0)
- Endocardial—Myocardial Interaction (1997) (0)
- [Chronic heart failure: structural and functional deficit of our health policy?]. (2004) (0)
- Heart failure : new insights into mechanisms and management : proceedings of the Fifth Antwerp-La Jolla-Kyoto Research Conference on Cardiac Function, held in Kyoto, Japan, December 13-15, 1995 (1996) (0)
- Heart Failure: Edited by Arnold M. Katz Lippincott Williams & Wilkins, Philadelphia (2000) 336 pages, illustrated, $45.00 ISBN:0‐7817‐1549‐0 (2000) (0)
- Ionotophoretic activation of isolated mammalian cardiac cells. (1976) (0)
- Length transients in load clamped cat papillary muscle. (1976) (0)
- Digitizing two dimensional echocardiographical images. (1981) (0)
- Endothelial-Ventricular Interaction in Normal and Diseased Hearts (1994) (0)
- Proceedings: Mechanical properties of subcellular cardiac preparations. (1975) (0)
- ENDOCARDIAL ENDOTHELIUM MODULATES INVIVO LEFT-VENTRICULAR PERFORMANCE (1993) (0)
- Load dependence of the physiologically sequenced tension fall tf in isolated mammalian cardiac muscle (1987) (0)
- 507 Assessment of chronic heart failure using gas exchange: importance of treadmill exercise versus bicycle exercise (2003) (0)
- Ventricular Relaxation: basic and clinical aspects (1985) (0)
- [Influence of hypertonic solutions on the pulmonary circulation]. (1960) (0)
- Heart failure: an epidemic of the XXIst century? (2007) (0)
- State of the art on heart failure syndrome. (1996) (0)
- Influence of length on sarcomere distribution in single cardiac cells (1980) (0)
- VENTRICULAR FUNCTION OF THE HEART IN ISCHEMIC HEART DISEASE (1983) (0)
- Discrimination between hypoxic and reoxygenation contracture of heart muscle (1978) (0)
- Does digoxin therapy affect outcome in patients with diastolic heart failure? (2007) (0)
- Proceedings: Influence of a physiological pumploading on isolated cat papillary muscle. (1975) (0)
- Left Ventricular Function in the Atlete: Analysis of Relaxation (1986) (0)
- Recent developments in cardiac ultrasonography. (1985) (0)
- [Paired electro-systolic pacing of the heart]. (1966) (0)
- Permeability of the endocardial endothelium in rat heart (1993) (0)
- [THE INDICATOR DILUTION METHOD IN THE PHYSIOLOGICAL AND PHYSIOPATHOLOGICAL STUDY OF THE CARDIOVASCULAR SYSTEM]. (1965) (0)
- Is the Total More Than the Sum of the Parts? (2005) (0)
- The cyclic interatrial pressure reversal: presence and behaviour during different breathing modes (1993) (0)
- Endocardial modulation of cardiac performance: implications for the evaluation of systolic relaxation. (1994) (0)
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