David Larry Sparks
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Biology
David Larry Sparks's Degrees
- PhD Neuroscience Stanford University
- Masters Biology Stanford University
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)David Larry Sparks's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The brainstem control of saccadic eye movements (2002) (775)
- Population coding of saccadic eye movements by neurons in the superior colliculus (1988) (744)
- Translation of sensory signals into commands for control of saccadic eye movements: role of primate superior colliculus. (1986) (709)
- Dissociation of visual and saccade-related responses in superior colliculus neurons. (1980) (614)
- The deep layers of the superior colliculus. (1989) (461)
- Trace amounts of copper in water induce β-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease (2003) (433)
- Corollary discharge provides accurate eye position information to the oculomotor system. (1983) (413)
- Saccades are spatially, not retinocentrically, coded. (1980) (404)
- Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results. (2005) (403)
- Size and distribution of movement fields in the monkey superior colliculus (1976) (363)
- Auditory receptive fields in primate superior colliculus shift with changes in eye position (1984) (359)
- Signal transformations required for the generation of saccadic eye movements. (1990) (356)
- Spatial localization of saccade targets. I. Compensation for stimulation-induced perturbations in eye position. (1983) (342)
- Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study. (2005) (313)
- Movement selection in advance of action in the superior colliculus (1992) (312)
- Sensorimotor integration in the primate superior colliculus. II. Coordinates of auditory signals. (1987) (305)
- Eye-head coordination during head-unrestrained gaze shifts in rhesus monkeys. (1997) (282)
- Functional properties of neurons in the monkey superior colliculus: Coupling of neuronal activity and saccade onset (1978) (270)
- Saccades to remembered target locations: an analysis of systematic and variable errors (1994) (256)
- Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease (2010) (248)
- Combined eye-head gaze shifts produced by electrical stimulation of the superior colliculus in rhesus monkeys. (1996) (247)
- Sensorimotor integration in the primate superior colliculus. I. Motor convergence. (1987) (238)
- Daily variation in the concentration of melatonin and 5-methoxytryptophol in the human pineal gland: effect of age and Alzheimer's disease (1990) (232)
- Peripheral ethanolamine plasmalogen deficiency: a logical causative factor in Alzheimer's disease and dementia Published, JLR Papers in Press, August 2, 2007. (2007) (224)
- Age-related distribution of neuropathologic changes in the cerebral cortex of patients with Down's syndrome. Quantitative regional analysis and comparison with Alzheimer's disease. (1995) (220)
- Activity of cells in the deeper layers of the superior colliculus of the rhesus monkey: evidence for a gaze displacement command. (1997) (216)
- Site and parameters of microstimulation: evidence for independent effects on the properties of saccades evoked from the primate superior colliculus. (1996) (199)
- Conceptual issues related to the role of the superior colliculus in the control of gaze (1999) (197)
- Movement fields of saccade-related burst neurons in the monkey superior colliculus (1980) (196)
- Sensori-motor integration in the primate superior colliculus (1991) (179)
- Cholesterol Accumulates in Senile Plaques of Alzheimer Disease Patients and in Transgenic APPsw Mice (2001) (174)
- Activation of microglia in the brains of humans with heart disease and hypercholesterolemic rabbits (1996) (167)
- Cerebellotectal pathways in the macaque: Implications for collicular generation of saccades (1990) (164)
- Sensory and motor maps in the mammalian superior colliculus (1987) (155)
- Neural cartography: sensory and motor maps in the superior colliculus. (1988) (155)
- Population coding of the direction, amplitude, and velocity of saccadic eye movements by neurons in the superior colliculus. (1990) (140)
- Abnormal central visual pathways in the brain of an albino green monkey (Cercopithecus aethiops) (1984) (139)
- The role of the superior colliculus in saccade initiation: a study of express saccades and the gap effect (2000) (136)
- Saccades to somatosensory targets. I. behavioral characteristics. (1996) (134)
- Spatial localization of saccade targets. II. Activity of superior colliculus neurons preceding compensatory saccades. (1983) (132)
- Innervation of monkey extraocular muscles: Localization of sensory and motor neurons by retrograde transport of horseradish peroxidase (1983) (125)
- Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology. (2006) (118)
- Coordination of the eyes and head: movement kinematics (2000) (116)
- Systematic errors for saccades to remembered targets: Evidence for a dissociation between saccade metrics and activity in the superior colliculus (1994) (115)
- Saccades to somatosensory targets. III. eye-position-dependent somatosensory activity in primate superior colliculus. (1996) (109)
- Altered serotonergic and cholinergic synaptic markers in Pick's disease. (1991) (109)
- Quantitative assessment of synaptic density in the outer molecular layer of the hippocampal dentate gyrus in Alzheimer's disease. (1996) (103)
- Amygdala cell loss and atrophy in Alzheimer's disease (1992) (93)
- Eye movements induced by pontine stimulation: interaction with visually triggered saccades. (1987) (91)
- Representation of averaging saccades in the superior colliculus of the monkey (1993) (88)
- Intraneuronal β-amyloid immunoreactivity in the CNS (1996) (87)
- Saccades to somatosensory targets. II. motor convergence in primate superior colliculus. (1996) (85)
- Response properties of eye movement-related neurons in the monkey superior colliculus (1975) (83)
- Deficits in saccades and fixation during muscimol inactivation of the caudal fastigial nucleus in the rhesus monkey. (2004) (79)
- Quantitative assessment of synaptic density in the entorhinal cortex in Alzheimer's disease (1993) (75)
- Immunohistochemical Localization of a Cytochrome P-450 Isozyme in Human Nasal Mucosa: Age-Related Trends (1993) (71)
- Firing patterns of reticular formation neurons during horizontal eye movements. (1971) (70)
- Nonstationary properties of the saccadic system: new constraints on models of saccadic control. (1995) (69)
- Effects of low-frequency stimulation of the superior colliculus on spontaneous and visually guided saccades. (1993) (63)
- The neural encoding of the location of targets for saccadic eye movements. (1989) (63)
- Simulations of saccade curvature by models that place superior colliculus upstream from the local feedback loop. (2005) (60)
- Patterns of adrenergic and peptidergic innervation in human olfactory mucosa: Age‐related trends (1993) (59)
- The nicotinic acetylcholine receptor, smoking, and Alzheimer's disease. (2002) (58)
- Is there a characteristic lipid profile in Alzheimer's disease? (2005) (57)
- Neural tract tracing using Di-I: a review and a new method to make fast Di-I faster in human brain (2000) (53)
- Cortical and subcortical contributions to coordinated eye and head movements (2001) (53)
- Unitary responses and discrimination learning in the squirrel monkey: The globus pallidus (1968) (48)
- The influence of unilateral and bilateral spreading depression during learning upon subsequent relearning. (1963) (48)
- Express saccades: the effects of spatial and temporal uncertainty (1993) (48)
- Aging and Alzheimer's disease. Altered cortical serotonergic binding. (1989) (48)
- Dissociation of eye and head components of gaze shifts by stimulation of the omnipause neuron region. (2007) (47)
- Sudden Infant Death Syndrome: Altered Aminergic-Cholinergic Synaptic Markers in Hypothalamus (1991) (47)
- Alzheimer's disease. Aminergic-cholinergic alterations in hypothalamus. (1988) (44)
- The Neural Control of Saccadic Eye Movements: The Role of the Superior Colliculus (1977) (44)
- The superior colliculus: A window for viewing issues in integrative neuroscience (1995) (41)
- Long- and short-term monocular deprivation in the rhesus monkey: effects on visual fields and optokinetic nystagmus (1986) (41)
- Saccade Dysmetria during Functional Perturbation of the Caudal Fastigial Nucleus in the Monkey (2003) (40)
- Two models for transforming auditory signals from head-centered to eye-centered coordinates (1993) (40)
- Human Olfactory Receptor Neurons Express Heat Shock Protein 70: Age-Related Trends (1995) (40)
- Effects of partial lidocaine inactivation of the paramedian pontine reticular formation on saccades of macaques. (2003) (39)
- A simple method for constructing microinjectrodes for reversible inactivation in behaving monkeys (2001) (39)
- Studies of the Role of the Paramedian Pontine Reticular Formation in the Control of Head‐Restrained and Head‐Unrestrained Gaze Shifts (2002) (38)
- The perihypoglossal projection to the superior colliculus in the rhesus monkey (1990) (38)
- Alterations in brain monoamine oxidase activity in aging, Alzheimer's disease, and Pick's disease. (1991) (38)
- Further Studies of the Neural Mechanisms of Ketamine‐Induced Anesthesia in the Rhesus Monkey (1975) (36)
- Changes in unit activity during stimuli associated with food and shock reinforcement (1967) (36)
- Determination of tyrosine, tryptophan and their metabolic derivatives by liquid chromatography-electrochemical detection: application to post mortem samples from patients with Parkinson's and Alzheimer's disease. (1985) (34)
- Single cell signals: an oculomotor perspective. (2003) (32)
- Component stretching during oblique stimulation-evoked saccades: the role of the superior colliculus. (1996) (31)
- Experimental control of eye and head positions prior to head-unrestrained gaze shifts in monkey (2001) (31)
- Water quality has a pronounced effect on cholesterol-induced accumulation of Alzheimer amyloid beta (Abeta) in rabbit brain. (2002) (30)
- Cholesterol metabolism and brain amyloidosis: evidence for a role of copper in the clearance of Abeta through the liver. (2007) (30)
- Oxidative Stress in Sudden Infant Death Syndrome (1996) (30)
- Neurochemical and Histopathologic Alterations Characteristic of Pick's Disease in a Non-demented Individual (1994) (29)
- The functional organization of the primate superior colliculus: a motor perspective. (1986) (29)
- Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer’s-like amyloid β in rabbit brain (2007) (28)
- The serotonin transporter promoter polymorphism and suicide (2006) (27)
- Ketamine‐Induced Anesthesia: Neural Mechanisms In the Rhesus Monkey (1973) (27)
- Cortical cathepsin D activity and immunolocalization in Alzheimer disease, critical coronary artery disease, and aging. (1996) (27)
- Coordination of eye and head components of movements evoked by stimulation of the paramedian pontine reticular formation (2008) (26)
- Alzheimer disease: Statins in the treatment of Alzheimer disease (2011) (26)
- Single unit activity related to behavior motivated by food reward (1968) (26)
- Role of the Monkey Superior Colliculus in the Spatial Localization of Saccade Targets (1983) (24)
- Saccades to remembered targets exhibit enhanced orbital position effects in monkeys (2001) (24)
- The role of population coding in the control of movement (1997) (24)
- Neural control of saccadic eye movements (1993) (24)
- Are gaze shifts controlled by a ‘moving hill’ of activity in the superior colliculus? (1993) (23)
- Reliability of oculomotor command signals carried by individual neurons (2007) (23)
- Cholesterol modifies classical conditioning of the rabbit (Oryctolagus cuniculus) nictitating membrane response. (2003) (23)
- Intraneuronal beta-amyloid immunoreactivity in the CNS. (1996) (23)
- Increased ALZ-50 Immunoreactivity in Sudden Infant Death Syndrome (1996) (23)
- Phospholipids block nuclear factor-kappa B and tau phosphorylation and inhibit amyloid-beta secretion in human neuroblastoma cells (2009) (22)
- Synaptic Neurochemistry of Human Striatum During Development: Changes in Sudden Infant Death Syndrome (1993) (22)
- Dynamics of primate oculomotor plant revealed by effects of abducens microstimulation. (2009) (21)
- Selective retrograde transneuronal transport of wheat germ agglutinin-conjugated horseradish peroxidase in the oculomotor system (2004) (21)
- Altered striatal dopaminergic metabolism 36 hours after unilateral trauma to the human mesencephalon (1987) (21)
- High dietary cholesterol facilitates classical conditioning of the rabbit's nictitating membrane response (2007) (21)
- Down's syndrome: occurrence of ALZ-50 reactive neurons and the formation of senile plaques (1992) (20)
- Classical conditioning of the rabbit's nictitating membrane response is a function of the duration of dietary cholesterol (2007) (19)
- Increased ALZ-50-Reactive Neurons in the Brains of SIDS Infants: An Indicator of Greater Neuronal Death? (1991) (18)
- Cholesterol increases ventricular volume in a rabbit model of Alzheimer's disease. (2012) (18)
- Cholesterol enhances classical conditioning of the rabbit heart rate response (2007) (18)
- Cholesterol and cognition: rationale for the AD cholesterol-lowering treatment trial and sex-related Differences in beta-amyloid accumulation in the brains of spontaneously hypercholesterolemic Watanabe rabbits. (2002) (18)
- Comparison of chemical methods for determining postmortem interval. (1989) (17)
- Anatomy of a new paired tract of the pineal gland in humans (1998) (17)
- Brain stem unit activity related to horizontal eye movements occurring during visual tracking. (1974) (15)
- Is Cholesterol a Culprit in Alzheimer's Disease? (2003) (14)
- Patterns of reticular unit activity observed during the performance of a discriminative task (1968) (14)
- Age-associated alteration of serotonergic synaptic neurochemistry in rat rostral hypothalamus (1985) (14)
- Commands for Coordinated Eye and Head Movements in the Primate Superior Colliculus (2003) (13)
- Studies on the effect of the apolipoprotein E genotype on the lipid profile in Alzheimer's disease. (2006) (12)
- Single unit responses related to sequences of food motivated behavior. (1968) (12)
- Statins to treat Alzheimer’s disease: an incomplete story (2012) (11)
- Erratum: Auditory receptive fields in primate superior colliculus shift with changes in eye position (1984) (11)
- Influence of Water Quality on Cholesterol-Induced Tau Pathology: Preliminary Data (2011) (11)
- An argument for using ethologically "natural" behaviors as estimates of unobservable sensory processes. Focus on "Sound localization performance in the cat: the effect of restraining the head". (2005) (11)
- Change in circulating C-reactive protein is not associated with atorvastatin treatment in Alzheimer's disease (2006) (10)
- The role of the primate superior colliculus in sensorimotor integration (1987) (10)
- 3-Methoxytyramine in the putamen as a gauge of the postmortem interval. (1986) (10)
- Influence of water quality on cholesterol induced systemic pathology. (2007) (9)
- Independent feedback control of horizontal and vertical amplitude during oblique saccades evoked by electrical stimulation of the superior colliculus. (1996) (9)
- On cholesterol levels and statins in cognitive decline and Alzheimer disease: progress and setbacks. (2009) (9)
- Dietary high cholesterol and trace metals in the drinking water increase levels of ABCA1 in the rabbit hippocampus and temporal cortex. (2015) (8)
- Computer control of eye position and velocity (1975) (8)
- Altered pineal serotonin binding in some suicides (1990) (8)
- Changing Views of the Role of Superior Colliculus in the Control of Gaze (2005) (8)
- Recommended technique for brain removal to retain anatomic integrity of the pineal gland in order to determine its size in sudden infant death syndrome. (1997) (8)
- ■ REVIEW : The Primate Superior Colliculus and the Control of Saccadic Eye Movements (1996) (8)
- The Neural Control of Orienting Eye and Head Movements (2003) (7)
- The Primate Superior Colliculus and the Control of Saccadic Eye Movements (2003) (7)
- Saccadic command signals in the superior colliculus: implications for sensorimotor transformations. (1988) (7)
- Saccade initiation and the reliability of motor signals involved in the generation of saccadic eye movements. (2006) (6)
- Relative spectral sensitivity to short wavelength light in the peripheral visual field (1975) (6)
- Properties of Saccade-Related Unit Activity In the Monkey Superior Colliculus (1978) (6)
- Vascular-Related and Mediated Alterations in Alzheimer’s Disease (1999) (5)
- Cellular localization of carnosinase in the human nasal mucosa. (1994) (5)
- KIF6 719Arg allele is associated with statin effects on cholesterol levels in amnestic mild cognitive impairment and Alzheimer's disease patients. (2012) (5)
- Interaction of evoked potentials in the anterior thalamus of the cat. (1966) (5)
- A head-mounted manipulator for chronic single unit recording from the squirrel monkey☆ (1967) (5)
- General discussion II (2006) (5)
- Copper Status in Alzheimer's Disease and Other Neurodegenerative Disorders: Genetics, Mechanisms, Neurophysiology, and Therapies (2011) (4)
- Irrelevant Aversive Stimulation as an Activator of an Appetitional Response: A Replication (1961) (4)
- THE AMYGDALA IN ALZHEIMERʼS DISEASE, AGING AND CORONARY ARTERY DISEASE; INCIDENCE OF SENILE PLAQUES AND ALTERED CHEMISTRY: 100 (1989) (3)
- Dopaminergic and serotonergic neurotransmitters in bone marrow transplant patients (1993) (3)
- Septum after-discharges and associated arterial pressure responses. (1968) (3)
- INCREASED CHOLESTEROL IN AD AND cCAD CORTEX, AND INCREASED CHOLESTEROL CONTENT AND FREE RADICAL ENZYME ACTIVITY IN RABBIT BRAIN DUE TO DIETARY CHOLESTEROL (1996) (3)
- Single unit activity during behavioral conditioning: arousal effects. (1967) (2)
- Brain markers and suicide: can a relationship be found? (1990) (1)
- P2-003 Cholesterol feeding enhances cerebral amyloid beta pathology in beagles (2004) (1)
- Disease progression of cognitive impairment in Alzheimer's disease: A model-based approach (2009) (1)
- Feedback Loop Place Superior Colliculus Upstream From the Local Simulations of Saccade Curvature by Models That (2015) (1)
- INCREASED NUMBERS OF ALZ-50 REACTIVE NEURONS PRECEDE SENILE PLAQUE (SP) FORMATION IN CRITICAL CORONARY ARTERY DISEASE (cCAD): 26 (1990) (1)
- Beyond Cholesterol: Statin Benefits in Alzheimer's Disease (2007) (1)
- APPEARANCE OF MICROGLIAL NODULES COINCIDES WITH PRESENCE OF SENILE PLAQUES IN DOWNʼS SYNDROME (1993) (1)
- Water quality and cholesterol-induced pathology: differential effects of the M-1 muscarinic receptor agonist Af267B on accumulation of Alzheimer-Like amyloid _ In rabbit brain (2005) (1)
- P3-201 Studies on the effect of the apolipoprotein E genotype on the lipid profile in Alzheimer’s disease (2006) (0)
- Diana L. Gallagher Introduction (2011) (0)
- Quantitative assessment of cortical synaptic density in patients with Alzheimer's disease and non-demented individuals with heart disease (1994) (0)
- Testing the predictions of different models of the saccadic system (1999) (0)
- Motor systems (1997) (0)
- Neural control (1995) (0)
- OXIDATIVE STRESS IN SIDS BRAIN: 236 (1995) (0)
- Hippocampal influences on septal unit activity. (1967) (0)
- Caudal Fastigial Nucleus in the Monkey Saccade Dysmetria in Head-Unrestrained Gaze Shifts After Muscimol Inactivation of the (2009) (0)
- A method of interfacing a small computer with psychological experiments. (1971) (0)
- Electrophysiological correlates of intracranial self-stimulation. (1965) (0)
- Postmortem accumulation of 3-methoxytyramine in the brain. (1984) (0)
- 2 Microcircuit of the Superior Colliculus A Neuronal Machine that Determines Timing and Endpoint of Saccadic Eye Movements (2005) (0)
- P3-004 The lipid profile in Alzheimer's disease (2004) (0)
- O2-04-02 Lipitor’s effect in Alzheimer’s dementia (LEADe) study: Baseline characteristics (2007) (0)
- ALTERED CEREBRAL CHEMISTRY AND ABUNDANT PICK BODIES WITHOUT OVERT DEMENTIA (1993) (0)
- Introduction: Sensori-motor integration (1991) (0)
- A Review of Lewy Body Disease (1998) (0)
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