Douglas Mcintosh Fambrough
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Douglas Mcintosh Fambroughbiology Degrees
Biology
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Genetics
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Molecular Biology
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Biology
Douglas Mcintosh Fambrough's Degrees
- PhD Molecular Biology Stanford University
- Bachelors Biochemistry University of California, Berkeley
Why Is Douglas Mcintosh Fambrough Influential?
(Suggest an Edit or Addition)Douglas Mcintosh Fambrough's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation (2001) (713)
- Neuromuscular Junction in Myasthenia Gravis: Decreased Acetylcholine Receptors (1973) (591)
- Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes (1999) (466)
- Control of acetylcholine receptors in skeletal muscle. (1979) (443)
- Chick myotendinous antigen. I. A monoclonal antibody as a marker for tendon and muscle morphogenesis (1984) (434)
- Genes that control neuromuscular specificity in Drosophila (1993) (418)
- The Biology of Isolated Chromatin (1968) (398)
- Acetylcholine receptor turnover in membranes of developing muscle fibers (1975) (318)
- Chick myotendinous antigen. II. A novel extracellular glycoprotein complex consisting of large disulfide-linked subunits (1984) (315)
- Calf and Pea Histone IV II. THE COMPLETE AMINO ACID SEQUENCE OF CALF THYMUS HISTONE IV; PRESENCE OF ε-N-ACETYLLYSINE (1969) (314)
- [96] Isolation and characterization of chromosomal nucleoproteins (1968) (301)
- Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump. (1988) (284)
- Calf and pea histone IV. 3. Complete amino acid sequence of pea seedling histone IV; comparison with the homologous calf thymus histone. (1969) (282)
- Acetylcholine Receptors : Distribution and extrajunctional density in rat diaphragm after denervation correlated with acetylcholine sensitivity (1972) (263)
- Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: Kinetic and morphological analysis (1987) (235)
- Molecular characterization and expression of the (Na+ + K+)‐ATPase alpha‐subunit in Drosophila melanogaster. (1989) (226)
- Aggregates of acetylcholine receptors are associated with plaques of a basal lamina heparan sulfate proteoglycan on the surface of skeletal muscle fibers (1983) (217)
- Acetylcholine Receptors (1974) (212)
- Development of acetylcholine sensitivity during myogenesis. (1971) (201)
- The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila. (1996) (193)
- Extracellular matrix organization in developing muscle: correlation with acetylcholine receptor aggregates (1984) (188)
- Nonequivalence of alpha-bungarotoxin receptors and acetylcholine receptors in chick sympathetic neurons. (1978) (178)
- Lysosomal membrane dynamics: structure and interorganellar movement of a major lysosomal membrane glycoprotein (1986) (165)
- Acetylcholine Sensitivity of Muscle Fiber Membranes: Mechanism of Regulation by Motoneurons (1970) (149)
- Acetylcholinesterase of human erythrocytes and neuromuscular junctions: homologies revealed by monoclonal antibodies. (1982) (145)
- On the similarity of plant and animal histones. (1966) (141)
- Newly synthesized acetylcholine receptors are located in the Golgi apparatus (1978) (140)
- Ultrastructural and electrophysiological correlates of cell coupling and cytoplasmic fusion during myogenesis in vitro. (1973) (140)
- The (Na+ + K+)-ATPase of chick sensory neurons. Studies on biosynthesis and intracellular transport. (1986) (139)
- The Drosophila beaten path Gene Encodes a Novel Secreted Protein That Regulates Defasciculation at Motor Axon Choice Points (1996) (135)
- Acetycholine receptor production and incorporation into membranes of developing muscle fibers. (1973) (134)
- Growth Factor-specific Signaling Pathway Stimulation and Gene Expression Mediated by ErbB Receptors* 210 (2001) (132)
- The immunoglobulin μ chains of membrane-bound and secreted IgM molecules differ in their C-terminal segments (1980) (122)
- Regulation of the (Na+ + K+)-ATPase in cultured chick skeletal muscle. Modulation of expression by the demand for ion transport. (1986) (122)
- Synthesis, transport and fate of acetylcholinesterase in cultured chick embryo muscle cells (1980) (120)
- An endogenous MDCK lysosomal membrane glycoprotein is targeted basolaterally before delivery to lysosomes (1991) (118)
- Secretion of acetylcholinesterase: Relation to acetylcholine receptor metabolism (1980) (111)
- Kinetics of biosynthesis of acetylcholine receptor and subsequent incorporation into plasma membrane of cultured chick skeletal muscle (1977) (110)
- Acetylcholine receptor degradation measured by density labeling: Effects of cholinergic ligands and evidence against recycling (1979) (107)
- Multiple forms of (Na+ + K+)-ATPase in the chicken. Selective detection of the major nerve, skeletal muscle, and kidney form by a monoclonal antibody. (1983) (106)
- Molecular Biology of Membrane Transport Disorders (1996) (104)
- Turnover of acetylcholine receptors in skeletal muscle. (1976) (100)
- Expression of fast and slow isoforms of the Ca2+-ATPase in developing chick skeletal muscle. (1987) (97)
- Sequence homology and role of cysteine in plant and animal arginine-rich histones. (1968) (95)
- Subunit Interactions in the Na,K-ATPase Explored with the Yeast Two-hybrid System* (1997) (94)
- Analysis of subunit assembly of the Na-K-ATPase. (1994) (92)
- The Drosophila abrupt gene encodes a BTB-zinc finger regulatory protein that controls the specificity of neuromuscular connections. (1995) (90)
- Electrophysiological properties of the membrane and acetylcholine receptor in developing rat and chick myotubes (1975) (89)
- Identification and molecular-genetic characterization of a LAMP/CD68-like protein from Caenorhabditis elegans. (2000) (89)
- Nucleotide sequences of avian cardiac and brain SR/ER Ca(2+)-ATPases and functional comparisons with fast twitch Ca(2+)-ATPase. Calcium affinities and inhibitor effects. (1991) (88)
- Apical plasma membrane mispolarization of NaK-ATPase in polycystic kidney disease epithelia is associated with aberrant expression of the beta2 isoform. (2000) (87)
- Fibronectin expression during myogenesis (1983) (86)
- Acetylcholine receptors. Revised estimates of extrajunctional receptor density in denervated rat diaphragm. (1974) (86)
- Structure of LEP100, a glycoprotein that shuttles between lysosomes and the plasma membrane, deduced from the nucleotide sequence of the encoding cDNA (1988) (86)
- Stability of Na(+)-K(+)-ATPase alpha-subunit isoforms in evolution. (1990) (85)
- Molecular forms of chicken embryo acetylcholinesterase in vitro and in vivo. Isolation and characterization. (1979) (85)
- Biosynthesis and degradation of acetylcholine receptors in rat skeletal muscles. Effects of electrical stimulation (1979) (82)
- 26 amino acids of an extracellular domain of the Na,K-ATPase alpha-subunit are sufficient for assembly with the Na,K-ATPase beta-subunit. (1994) (82)
- The alternative carboxyl termini of avian cardiac and brain sarcoplasmic reticulum/endoplasmic reticulum Ca(2+)-ATPases are on opposite sides of the membrane. (1992) (79)
- Different Steady State Subcellular Distributions of the Three Splice Variants of Lysosome-associated Membrane Protein LAMP-2 Are Determined Largely by the COOH-terminal Amino Acid Residue (1997) (76)
- Pre-translational regulation of the (Na+ + K+)-ATPase in response to demand for ion transport in cultured chicken skeletal muscle. (1990) (73)
- Expression of avian Ca2+-ATPase in cultured mouse myogenic cells (1989) (71)
- The family of LAMP-2 proteins arises by alternative splicing from a single gene: characterization of the avian LAMP-2 gene and identification of mammalian homologs of LAMP-2b and LAMP-2c. (1995) (65)
- Expression of hybrid (Na+ + K+)-ATPase molecules after transfection of mouse Ltk-cells with DNA encoding the beta-subunit of an avian brain sodium pump. (1987) (65)
- A mutation of the drosophila sodium pump α subunit gene results in bang-sensitive paralysis (1994) (63)
- The sodium pump becomes a family (1988) (63)
- The pathway and targeting signal for delivery of the integral membrane glycoprotein LEP100 to lysosomes (1992) (60)
- Utilization of the indirect lysosome targeting pathway by lysosome-associated membrane proteins (LAMPs) is influenced largely by the C-terminal residue of their GYXXphi targeting signals. (1999) (59)
- Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence. (1968) (58)
- Limited molecular heterogeneity of plant histones. (1969) (56)
- From growth cone to synapse: the life history of the RP3 motor neuron. (1993) (49)
- Multiple mRNAs encode the avian lysosomal membrane protein LAMP-2, resulting in alternative transmembrane and cytoplasmic domains. (1995) (46)
- Synthesis of acetylcholine receptors by cultured chick myotubes and denervated mouse extensor digitorum longus muscles. (1976) (45)
- Ionic properties of the acetylcholine receptor in cultured rat myotubes (1975) (42)
- Cytoplasmic and transmembrane domain deletions of Na,K-ATPase beta-subunit. Effects on subunit assembly and intracellular transport. (1991) (42)
- Ca(2+)-dependent and thapsigargin-inhibited phosphorylation of Na+,K(+)-ATPase catalytic domain following chimeric recombination with Ca(2+)-ATPase. (1993) (41)
- Acetylcholinesterase‐immunoreactive axonal network in monkey visual cortex (1984) (41)
- Identification of a Ca2+-ATPase in cerebellar Purkinje cells. (1989) (40)
- Assembly of the extracellular domain of the Na,K-ATPase beta subunit with the alpha subunit. Analysis of beta subunit chimeras and carboxyl-terminal deletions. (1993) (40)
- RECEPTOR PROPERTIES OF DEVELOPING MUSCLE (1974) (40)
- P-type ATPases in Caenorhabditis and Drosophila: Implications for Evolution of the P-type ATPase Subunit Families with Special Reference to the Na,K-ATPase and H,K-ATPase Subgroup (2003) (38)
- Synthesis, insertion into the plasma membrane, and turnover of alpha- bungarotoxin receptors in chick sympathetic neurons (1979) (38)
- Chapter 8 Differential Subunit and Isoform Expression Involved in Regulation of Sodium Pump in Skeletal Muscle (1989) (36)
- Assembly of Na,K-ATPase α-subunit isoforms with Na,K-ATPase β-subunit isoforms and H,K-ATPase β-subunit (1994) (35)
- Skeletal Muscle (1982) (35)
- The carboxyl-terminal 161 amino acids of the Na,K-ATPase alpha-subunit are sufficient for assembly with the beta-subunit. (1992) (33)
- Regulation of the sodium pump in excitable cells. (1987) (30)
- Characterization of a plasma membrane glycoprotein common to myoblasts, skeletal muscle satellite cells, and glia. (1983) (30)
- A mutation of the Drosophila sodium pump alpha subunit gene results in bang-sensitive paralysis. (1994) (29)
- Mutation of a conserved proline residue in the beta-subunit ectodomain prevents Na(+)-K(+)-ATPase oligomerization. (1993) (29)
- Structure of a gene for a lysosomal membrane glycoprotein (LEP100). Housekeeping gene with unexpected exon organization. (1990) (27)
- Are muscle fibers denervated in myotonic dystrophy? (1976) (26)
- Calf and pea histone IV. II. The complete amino acid sequence of calf thymus histone IV; presence of epsilon-N-acetyllysine. (1969) (25)
- Selective dissociation of pea bud nucleohistone. (1968) (24)
- Differential distribution of the alternative forms of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, SERCA2b and SERCA2a, in the avian brain (1993) (22)
- Membrane permeability : 100 years since Ernest Overton (1999) (22)
- Specificity of Nerve-Muscle Interactions (1976) (22)
- Studies on the Na+-K+ ATPase of skeletal muscle and nerve. (1983) (22)
- Molecular dissection of functional domains of the E1E2-ATPase using sodium and calcium pump chimeric molecules. (1992) (21)
- Sequence analysis of DNA encoding an avian Na+, K+-ATPase β2-subunit (1993) (20)
- Expression of Ca2(+)-ATPase isoforms in denervated, regenerating, and dystrophic chicken skeletal muscle. (1991) (20)
- (Na+ + K+)-ATPase correlated with a major group of intramembrane particles in freeze-fracture replicas of cultured chick myotubes (1983) (19)
- Immunocytochemical and quantitative studies of Na+,K+-ATPase distribution in the developing chick cochlea (1987) (19)
- The Drosophila Na,K-ATPase alpha-subunit gene: gene structure, promoter function and analysis of a cold-sensitive recessive-lethal mutation. (1997) (16)
- The life history of acetylcholine receptors. (1979) (16)
- Monoclonal Antibodies to Skeletal Muscle Cell Surface (1982) (12)
- Subunit Interactions in the Sodium Pump a (1997) (11)
- Neuronal Recognition (1976) (11)
- Quantitative analysis of dicer substrate oligonucleotides in mouse liver by ultra-high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. (2012) (11)
- A cell biologist's perspective on sites of Na,K-ATPase regulation. (1991) (10)
- A discussion of neuron and muscle cell cultures. (1973) (10)
- The Biology of Isolated Chromatin: Chromosomes, biologically active in the test tube, provide a powerful tool for the study of gene action. (1968) (10)
- Reduced acetylcholine receptors in myasthenia gravis. (1973) (9)
- Negative transcriptional regulation of the chicken Na+/K+-ATPase α1-subunit gene (1996) (9)
- Intramolecular fusion of Na pump subunits assures exclusive assembly of the fused alpha and beta subunit domains into a functional enzyme in cells also expressing endogenous Na pump subunits. (1993) (9)
- Chapter 3 Structural Requirements for Subunit Assembly of the Na, K-ATPase (1994) (8)
- Molecular evolution of the calcium-transporting ATPases analyzed by the maximum parsimony method. (1994) (8)
- Maintenance State of the Art Report (1982) (7)
- Carboxy-terminal regions of the sarcoplasmic/endoplasmic reticulum Ca(2+)- and the Na+/K(+)-ATPases control their K+ sensitivity. (1997) (7)
- Points of view: a survey of survey courses: are they effective? (2005) (7)
- Denervation: Cholinergic Receptors of Skeletal Muscle (1981) (7)
- Assembly of Na,K-ATPase alpha-subunit isoforms with Na,K-ATPase beta-subunit isoforms and H,K-ATPase beta-subunit. (1994) (7)
- Metabolism of acetylcholine receptors in skeletal muscle. (1978) (7)
- Negative transcriptional regulation of the chicken Na+/K(+)-ATPase alpha 1-subunit gene. (1996) (6)
- Cation Transport ATPases (1996) (6)
- Properties of Acetylcholine Receptor Turnover in Cultured Embryonic Muscle Cells (1978) (6)
- Movement of Ca(2+)-ATPase molecules within the sarcoplasmic/endoplasmic reticulum in skeletal muscle. (1996) (5)
- [27] Biosynthesis and intracellular transport of acetylcholine receptors (1983) (5)
- Sequence analysis of DNA encoding an avian Na+,K(+)-ATPase beta 2-subunit. (1993) (4)
- Expression of the Avian Na,K-ATPase Subunits in Dictyostelium discoideum (1999) (4)
- The Na+, K+-pump part A: Molecular aspects (progress in clinical and biological research, vol. 268A) edited by Jens C. Skou, Jens G. Norby, Arvid B. Maunsbach and Mikael Esmann, Alan R. Liss, 1988. £101.50 ISBN 0 845 154 001 (1989) (4)
- Cellular origin of extracellular matrix components during muscle morphogenesis revealed by monoclonal antibodies. (1982) (4)
- Structural analysis and expression of a chromosomal gene encoding an avian Na+K+-ATPase β1-subunit (1993) (4)
- Biosynthesis and turnover of nicotinic acetylcholine receptors (1981) (4)
- Acetylcholine Receptors (1972) (4)
- Aspects of Neural Ontogeny. A. F. W. Hughes. Logos Press, London; Academic Press, New York, 1968. xii + 249 pp., illus. $12.50 (1968) (3)
- Weathering a storm (2012) (3)
- Synthesis, transport, and fate of acetylcholinesterase and acetylcholine receptors in cultured muscle. (1982) (3)
- Metabolism of Cell Surface Receptors (1982) (2)
- Turnover of acetylcholine receptors in skeletal muscle. (1982) (2)
- Points of View: A Survey of Survey Courses: Are They Effective? A Case for Survey Courses in Biology (2005) (2)
- Molecular evolution of physiological processes : Society of General Physiologists, 47th Annual Symposium, Marine Biological Laboratory, Woods Hole, Massachusetts, 8-11 September 1993 (1994) (2)
- News, opinion and letters (1973) (2)
- Biosynthesis and intracellular transport of acetylcholine receptors. (1983) (1)
- Developmental and regulatory aspects of the sodium- and potassium-ion-stimulated ATPase in avian nerve and muscle. (1985) (1)
- From growth cone to synapse: the life history of the RP3 motor neuron. (1993) (1)
- Structural analysis and expression of a chromosomal gene encoding an avian Na+/K(+)-ATPase beta 1-subunit. (1993) (1)
- Proteins of excitable membranes. (1987) (1)
- Structure of a Gene for a Lysosomal Membrane Glycoprotein (LEPlOO) HOUSEKEEPING GENE (2001) (1)
- Motor Innervation of Muscle. S. Thesleff (1977) (1)
- Identification of a Ca 2 +-ATPase in cerebellar Purkinje cells (2015) (1)
- The biology of isolated chromatin. Chromosomes, biologically active in the test tube, provide a powerful tool for the study of gene action. (1968) (0)
- Mental K rations The Receptors: A Comprehensive Treatise. Volume 1, General Principles and Procedures. R. D. O'Brien, ed. R. D. O'Brien, ed. New York: Plenum, 345 pp. $29.50 (1980) (0)
- Structural Requirements for the Interaction between the Na + /K + -ATPase α - and β-Subunits (1994) (0)
- Structure function studies of sodium potassium atpase isozymes (1990) (0)
- Studies on Plant and Animal Histones (1968) (0)
- 1578 – REGULATION OF CHOLINERGIC RECEPTOR METABOLISM IN SKELETAL MUSCLE (1978) (0)
- Preliminary announcement (2004) (0)
- Biological Messages: Communication in Development . Twenty-eighth symposium, Society for Developmental Biology, Boulder, Colo., June 1969. Anton Lang, Ed. Academic Press, New York, 1970. xii, 272 pp., illus. $12. Developmental Biology, Supplement 3. (1971) (0)
- Compressing the plasma membrane The plasma membrane. Transport in the life sciences. Volume 6. by S. K. Malhotra New York: John Wiley & Sons, Inc. (1983). 209 pp. $69.95 (1984) (0)
- Some Observations on Denervation Supersensitivity in Skeletal Muscle (1979) (0)
- Amino Acids of an Extracellular Domain of the Na , K-ATPase a-Subunit Are Sufficient for Assembly with the Na , K-ATPase p-Subunit * (2001) (0)
- Sodium pump gene family in the chicken (1987) (0)
- Supporting US public health experts (2020) (0)
- Aspects of Receptor Systems Possibly Relevant to Neuron-Glial Interactions and Multiple Sclerosis (1982) (0)
- Differential Immediate Early Gene Expression Induced by (2001) (0)
- Spliced cDNAs Encode the Chicken sarco / Endoplasmic Reticulum Slow Ca 2 + (2015) (0)
- (Na ÷ + K÷)-ATPase Correlated of Intramembrane Particles in of Cultured Chick Myotubes with a Major Group Freeze-Fracture Replicas (2003) (0)
- Review of: Bio2010: transforming undergraduate education for future research biologists, by the National Research Council. Bio2010: read it! (2003) (0)
- Acetylcholinesterase of human eryl junctions: Homologies revealed by ) (membrane proteins/extracellular matrix/acetylcholine receptors/nel (2016) (0)
- Author Correction: Supporting US public health experts (2020) (0)
- Book Review:Membranes and Transport. Volume 1 and Volume 2. Anthony N. Martonosi (1983) (0)
- Trophic functions of the neuron. I. Development of neural connections. Receptor properties of developing muscle. (1974) (0)
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What Schools Are Affiliated With Douglas Mcintosh Fambrough?
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