Daniel Martin Ziegler
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Daniel Martin Zieglerbiology Degrees
Biology
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Molecular Biology
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Biochemistry
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Chemistry Biology
Daniel Martin Ziegler's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
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(Suggest an Edit or Addition)Daniel Martin Ziegler's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Role of reversible oxidation-reduction of enzyme thiols-disulfides in metabolic regulation. (1985) (726)
- Flavin-containing monooxygenases: catalytic mechanism and substrate specificities. (1988) (330)
- The enzymes of detoxication. (1983) (318)
- Microsomal oxidase. IV. Properties of a mixed-function amine oxidase isolated from pig liver microsomes. (1972) (246)
- Recent studies on the structure and function of multisubstrate flavin-containing monooxygenases. (1993) (237)
- Chapter 9 – Microsomal Flavin-Containing Monooxygenase: Oxygenation of Nucleophilic Nitrogen and Sulfur Compounds (1980) (216)
- FORMATION OF AN INTERMEDIATE N-OXIDE IN THE OXIDATIVE DEMETHYIATION OF N,N-DIMETHYIANILINE CATALYZED BY LIVER MICROSOMES. (1964) (202)
- AN OVERVIEW OF THE MECHANISM, SUBSTRATE SPECIFICITIES, AND STRUCTURE OF FMOs (2002) (195)
- Alcohol mixed function. Oxidase activity of mammalian liver microsomes. (1965) (178)
- The liver microsomal FAD-containing monooxygenase. Spectral characterization and kinetic studies. (1979) (171)
- Microsomal-catalyzed hydroperoxide-dependent C-oxidation of amines. (1973) (164)
- S-oxidation of thioureylenes catalyzed by a microsomal flavoprotein mixed-function oxidase. (1974) (138)
- Flavin-containing monooxygenases: enzymes adapted for multisubstrate specificity. (1990) (129)
- The relative participation of liver microsomal amine oxidase and cytochrome P-450 in N-demethylation reactions. (1977) (126)
- The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression. (1994) (123)
- Studies on the electron transport system. XLIII. The isolation of a succinic-coenzyme Q reductase from beef heart mitochondria (1962) (123)
- S-Oxygenation of N-substituted thioureas catalyzed by the pig liver microsomal FAD-containing monooxygenase. (1979) (122)
- Cytochrome P-450- and flavin-containing monooxygenase-catalyzed formation of the carcinogen N-hydroxy-2-aminofluorene and its covalent binding to nuclear DNA. (1982) (118)
- Microsomal oxidases. I. The isolation and dialkylarylamine oxygenase activity of pork liver microsomes. (1966) (114)
- Studies on the mechanism of oxidative phosphorylation. V. The phosphorylating properties of the electron transport particle. (1958) (107)
- Rabbit lung flavin-containing monooxygenase is immunochemically and catalytically distinct from the liver enzyme. (1984) (102)
- Simplified methods for the estimation of iron in mitochondria and submitochondrial fractions. (1962) (102)
- Studies on the mechanism of oxidative phosphorylation. I. Preparation and properties of a phosphorylating electron transfer particle from beef heart mitochondria. (1957) (99)
- Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum. (1999) (95)
- Protein disulfide bond synthesis: a possible intracellular mechanism (1977) (86)
- Multisubstrate flavin-containing monooxygenases: applications of mechanism to specificity. (1995) (85)
- Cloning, primary sequence, and chromosomal mapping of a human flavin-containing monooxygenase (FMO1). (1991) (84)
- Reduced pyridine nucleotide-dependent N-hydroxy amine oxidase and reductase activities of hepatic microsomes. (1973) (76)
- [14] Hepatic microsomal mixed-function amine oxidase (1978) (72)
- The distinct nature and function of NADPH-cytochrome c reductase and the NADPH-dependent mixed-function amine oxidase of porcine liver microsomes. (1971) (68)
- Properties of a NADH-dependent N-hydroxy amine reductase isolated from pig liver microsomes. (1974) (68)
- Role of Reversible Oxidation-Reduction of Enzyme Thiols-Dilsulfides in Metabolic Regulation (1985) (68)
- Contribution of N-oxygenation to the metabolism of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) by various liver preparations. (1986) (68)
- Microsomal flavoprotein-catalyzed N-oxidation of arylamines. (1973) (68)
- Studies on the electron transport system. XI. Correlation of the morphology and enzymic properties of mitochondrial and sub-mitochondrial particles. (1958) (67)
- Studies on the electron transport system. XIII. Mitochondrial structure and dehydrogenase activity in isolated mitochondria. (1958) (66)
- Substrate specificity of the rabbit lung flavin-containing monooxygenase for amines: oxidation products of primary alkylamines. (1986) (65)
- Dimethylaniline N-oxidase and aminopyrine N-demethylase activities of human liver tissue. (1973) (65)
- Substrate specificities of rabbit lung and porcine liver flavin-containing monooxygenases: differences due to substrate size. (1990) (60)
- [42] Preparation and properties of succinate dehydrogenase-coenzyme Q reductase (complex II) (1967) (60)
- Size limits of thiocarbamides accepted as substrates by human flavin-containing monooxygenase 1. (2000) (57)
- Rat liver oxidative N-dealkylase and N-oxidase activities as a function of animal age. (1970) (54)
- The flavin-containing monooxygenase expressed in pig liver: primary sequence, distribution, and evidence for a single gene. (1990) (52)
- The catalytic demethylation of N,N-dimethylaniline-N-oxide by liver microsomes☆ (1963) (52)
- Molecular cloning and kinetic characterization of a flavin-containing monooxygenase from Saccharomyces cerevisiae. (1996) (52)
- Microsomal oxidases. 3. Comparison of species and organ distribution of dialkylarylamine N-oxide dealkylase and dialkylarylamine N-oxidase. (1968) (52)
- Interaction of primary amines with a mixed-function amine oxidase isolated from pig liver microsomes. (1971) (51)
- Microsomal oxidases. II. Properties of a pork liver microsomal N-oxide dealkylase. (1966) (50)
- The role of flavin-containing monooxygenase in the N-oxidation of the pyrrolizidine alkaloid senecionine. (1989) (48)
- Increased biliary GSSG efflux from rat livers perfused with thiocarbamide substrates for the flavin-containing monooxygenase. (1984) (48)
- THE PROPERTIES OF A PURIFIED HEPATIC MICROSOMAL MIXED FUNCTION AMINE OXIDASE (1969) (47)
- Changes in dimethylaniline N-oxidase activity of mouse liver and kidney induced by steroid sex hormones. (1981) (46)
- On the reduction of externally added DPN by succinate in submitochondrial particles. (1961) (45)
- Liver microsome and flavin-containing monooxygenase catalyzed oxidation of organic selenium compounds. (1994) (43)
- Studies on substrate specificity of the hog liver flavin-containing monooxygenase. Anionic organic sulfur compounds. (1987) (43)
- The isolation and properties of a soluble succinic coenzyme Q reductase from reef heart mitochondria (1959) (43)
- Microsomal mixed-function oxidase-dependent renaturation of reduced ribonuclease. (1977) (42)
- Stereoselectivity in the N'-oxidation of nicotine isomers by flavin-containing monooxygenase. (1988) (40)
- Studies on the electron transfer system. XXV. The isolation and properties of a lipoflavoprotein with diaphorase activity from beef heart mitochondria. (1959) (37)
- Role of the microsomal mixed-function amine oxidase in the oxidation of N,N-disubstituted hydroxylamines. (1974) (35)
- N-methylation: potential mechanism for metabolic activation of carcinogenic primary arylamines. (1988) (35)
- The 1990 Bernard B. Brodie Award Lecture. Unique properties of the enzymes of detoxication. (1991) (33)
- Redox regulation of yeast flavin-containing monooxygenase. (2000) (33)
- Use of thiocarbamides as selective substrate probes for isoforms of flavin-containing monooxygenases. (1992) (32)
- The requirement for flavin adenine dinucleotide by a liver microsmal oxygenase catalyzing the oxidation of alkylaryl amines. (1964) (31)
- [58] Electron transport particles (1963) (31)
- Estimation of flavin-containing monooxygenase activities in crude tissue preparations by thiourea-dependent oxidation of thiocholine. (1991) (29)
- NADPH-dependent oxidation of reduced ebselen, 2-selenylbenzanilide, and of 2-(methylseleno)benzanilide catalyzed by pig liver flavin-containing monooxygenase. (1992) (29)
- Microsomal mixed-function amine oxidase. Oxidation products of piperazine-substituted phenothiazine drugs. (1978) (29)
- Metabolic oxygenation of organic nitrogen and sulfur compounds (1984) (29)
- Oxidation of aldehydes catalyzed by pig liver flavin-containing monooxygenase. (1995) (28)
- Oxidative phosphorylation by an electron transport particle from beef heart. (1956) (28)
- Mechanism of 2-naphthylamine oxidation catalysed by pig liver microsomes. (1976) (26)
- Studies on the nature and regulation of the cellular thio:disulphide potential. (1979) (26)
- Cellular protein-mixed disulfides. (1987) (23)
- Synthesis of N-oxides with a hepatic microsomal drug oxidase insolubilized on artificial matrices. (1974) (23)
- Sequence of components in the succinic chain of the mitochondrial electron transport system. (1959) (20)
- Intermediate metabolites of thiocarbamides, thioureylenes and thioamides: mechanism of formation and reactivity. (1978) (20)
- Oxidative metabolism of tertiary amine drugs by human liver tissue. (1971) (19)
- Chapter 9 – Functional Groups Bearing Sulfur (1982) (19)
- Oxidation of desmethylpromethazine catalyzed by pig liver flavin-containing monooxygenase. Number and nature of metabolites. (1993) (18)
- Hepatic microsomal mixed-function amine oxidase. (1978) (18)
- N-Glycosylation of pig flavin-containing monooxygenase form 1: determination of the site of protein modification by mass spectrometry. (1998) (17)
- Studies on the biliary efflux of GSH from rat liver due to the metabolism of aminopyrine. (1985) (17)
- Estimation of amine oxides in the presence of hepatic microsomes. (1970) (17)
- Bioactivation of xenobiotics by flavin-containing monooxygenases. (1991) (16)
- Studies on the electron transfer system. 29. The isolation and properties of a succinic dehydrogenase-cytochrome b complex from beef-heart mitochondria. (1960) (16)
- The oxidation of ebselen metabolites to thiol oxidants catalyzed by liver microsomes and perfused rat liver. (1995) (15)
- Cysteamine and cystamine. (1987) (15)
- Application of an insolubilized hepatic microsomal drug oxidase to the continous production of N‐oxides (1975) (15)
- Studies on the mechanism of oxidative phosphorylation. II. Role of bound pyridine nucleotide in phosphorylation. (1957) (14)
- Hamster hepatic nuclear mixed-function amine oxidase: location and specific activity. (1980) (13)
- Inhibition of purified and membrane-bound flavin-containing monooxygenase 1 by (N,N-dimethylamino)stilbene carboxylates. (1996) (13)
- A quantitative micro method for the estimation of amine oxides. (1969) (12)
- Immunochemical studies utilizing antibody to NADPH-cytochrome c reductase as a specific inhibitor of microsomal electron transport. (1971) (12)
- KINETIC STUDIES ON MECHANISM AND SUBSTRATE SPECIFICITY OF THE MICROSOMAL FLAVIN–CONTAINING MONOOXYGENASE (1980) (12)
- The isolation of a functionally intact succinic dehydrogenase-cytochrome b complex from beef heart mitochondria. (1959) (12)
- Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiae. (1999) (11)
- Estimation of lipid concentrations on thin-layer plates by densitometry of transparent copies. (1988) (10)
- Mechanism, multiple forms and substrate specificities of flavin-containing mono-oxygenases (1991) (10)
- Effect of SKF 525-A on the excretion of amine oxides by the rat. (1968) (10)
- Nitroglycerin and isosorbide dinitrate stimulation of glutathione disulfide efflux from perfused rat liver. (1989) (9)
- Effect of hypoxic perfusion on hepatic concentration and biliary release of glutathione disulfide. (1988) (9)
- Properties of an N,N-dimethyl-p-aminoazobenzene oxide reductase purified from rat liver cytosol. (1986) (8)
- Properties and applications of an immobilized mixed-function hepatic drug oxidase. (1976) (7)
- Fractionation of pituitary homogenates by differential centrifugation. I. Association of hormonal activity with subcellular fractions. (1956) (6)
- [65] Oxygen radicals and drugs: In vitro measurements (1990) (5)
- S -Oxygenation in Herbicide Metabolism in Mammals (1978) (5)
- Mechanisms for the generation of oxygen radicals by drugs. (1988) (4)
- Permeability of adolescent rat intestine to pancreatic ribonuclease. (1982) (3)
- Oxidation of aldose reductase inhibitors ALO-4114 and ALO-3152 catalyzed by liver microsomes. (1992) (3)
- Activation of the amino acid-incorporating system of rat liver slices upon incubation. (1955) (3)
- Oxygen radicals and drugs: in vitro measurements. (1990) (3)
- FLAVOENZYMES INHIBITED BY INDOMETHACIN (1994) (3)
- Cysteamine dioxygenase. (1987) (2)
- Substrate specificity of the rabbit lung flavin containing monooxygenase rl fmo for amines phenothiazines differing in length of the tertiary amine side chain (1988) (2)
- 19 – A BIOCHEMICAL MECHANISM FOR THE OXIDATION OF GLUTATHIONE BY XENOBIOTIC THIOLS (1989) (2)
- Fractionation of pituitary homogenates by differential centrifugation. II. Distribution of the amino acid-incorporating system. (1956) (1)
- Lipid Peroxidation: The Role of Hepatic FAD-Monooxygenase (1980) (1)
- Fractionation of Pituitary Tissue by Differential Centrifugation (1955) (1)
- Primary Sequence , and Chromosomal Mapping of a Human Flavin-containing Monooxygenase ( FMOl ) * (2001) (0)
- Tissue and biliary glutathione disulfide in the perfused vitamin E-deficient rat liver. (1989) (0)
- Substrate Specificity of Human Flavin-containing monooxygenase 1 (2000) (0)
- Cytochrome P-450-and Flavin-containing Monooxygenase-catalyzed Formation of the Carcinogen A /-Hydroxy-2-aminofluorene and Its Covalent Binding to Nuclear DMA 1 (2006) (0)
- STRUCTURAL STUDIES ON THE PORCINE LIVER MULTISUBSTRATE FLAVIN-CONTAINING MONOOXYGENASE (1991) (0)
- [27] Estimation of tissue cysteamine by quantitative thin-layer chromatography (1995) (0)
- OXID.ATION-REDUC TION OF ENZYME THIOLS-DISULFIDE S IN METABOLIC REGULATION (1985) (0)
- Estimation of tissue cysteamine by quantitative thin-layer chromatography. (1995) (0)
- FRACTIONATION OF PITUITARY HOMOGENATES BY DIFFERENTIAL CENTRIFUGATION (2003) (0)
- Opening Remarks (1989) (0)
- Cloning of cDNAs to the hepatic microsomal flavin-containing monooxygenase: application to molecular genetic studies of polymorphic trimethylamine N-oxidation (1990) (0)
- Cytochrome P-450- and Flavin-containing Monooxygenase-catalyzed Formation of the Carcinogen A/-Hydroxy-2-aminofluorene and Its Covalent Binding to Nuclear DMA1 (2006) (0)
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Daniel Martin Ziegler is affiliated with the following schools:
