Derek Parry Gastroenter Jewell

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Derek Parry Gastroenter Jewell

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Derek Parry Gastroenter Jewell's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (2007) (9208)
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. (2005) (2917)
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease (2008) (2621)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants (2007) (1421)
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility (2007) (1227)
A Simple Classification of Crohn's Disease: Report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998 (2000) (1189)
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation (2010) (1018)
Two stage genome–wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12 (1996) (740)
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21 (2007) (686)
The molecular classification of the clinical manifestations of Crohn's disease. (2002) (643)
The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review (2002) (614)
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (600)
In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope (2000) (572)
A comparison of budesonide with prednisolone for active Crohn's disease. (1994) (557)
Intensive intravenous regimen for severe attacks of ulcerative colitis. (1974) (540)
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region (2009) (513)
Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres. (1988) (495)
Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history (1998) (481)
Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls (2010) (465)
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. (2005) (463)
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease (2008) (455)
Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease (2010) (421)
Predicting outcome in severe ulcerative colitis. (1996) (410)
Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease (1996) (372)
Coeliac disease in primary care: case finding study (1999) (355)
Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease (2005) (338)
Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. (2005) (338)
Lymphocyte subset reference ranges in adult Caucasians. (1991) (328)
Food intolerance and the irritable bowel syndrome. (1989) (311)
Azathioprine in Ulcerative Colitis: Final Report on Controlled Therapeutic Trial (1974) (303)
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. (2002) (282)
Genetic markers may predict disease behavior in patients with ulcerative colitis. (1997) (279)
Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility (2000) (268)
Controlled trial of intravenous metronidazole as an adjunct to corticosteroids in severe ulcerative colitis. (1986) (266)
Expression of HLA-DR antigens by colonic epithelium in inflammatory bowel disease. (1983) (256)
Intestinal lymphocyte subpopulations in inflammatory bowel disease: an analysis by immunohistological and cell isolation techniques. (1984) (250)
Oral budesonide for prevention of postsurgical recurrence in Crohn's disease. The IOIBD Budesonide Study Group. (1999) (249)
NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population (2003) (245)
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease. (2000) (244)
A Comparison of Budesonide and Mesalamine for Active Crohn's Disease (1998) (236)
Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project (2012) (235)
Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes. (2002) (222)
The lactulose hydrogen breath test as a diagnostic test for small-bowel bacterial overgrowth. (1979) (210)
Budesonide prolongs time to relapse in ileal and ileocaecal Crohn's disease. A placebo controlled one year study. (1996) (204)
The association of autoimmune disorders with inflammatory bowel disease. (1989) (204)
Ciclosporin use in acute ulcerative colitis: a long-term experience (2005) (199)
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. (2009) (199)
Role of the faecal stream in the maintenance of Crohn's colitis. (1985) (199)
IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel Disease (2007) (199)
Contribution of the MHC region to the familial risk of coeliac disease (1999) (189)
Pelvic and perineal complications of Crohn's disease: assessment using magnetic resonance imaging. (1995) (187)
Clinical relevance of advances in genetics and pharmacogenetics of IBD. (2004) (184)
The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. (2013) (180)
Fistulating Anal Crohn’s Disease: Results of Combined Surgical and Infliximab Treatment (2006) (172)
Indeterminate colitis: A review of the concept — What's in a name? (2008) (170)
Genotype-phenotype analysis of the Crohn’s disease susceptibility haplotype on chromosome 5q31 (2003) (168)
T lymphocyte subsets in human intestinal mucosa: the distribution and relationship to MHC-derived antigens. (1981) (168)
Characterization of Inflammatory Bowel Disease With Urinary Metabolic Profiling (2009) (167)
Cancer surveillance in ulcerative colitis (2005) (161)
Lymphocyte subpopulations in the human small intestine. The findings in normal mucosa and in the mucosa of patients with adult coeliac disease. (1983) (161)
Circulating immune complexes in inflammatory bowel disease. (1973) (161)
Mucosal characteristics of pelvic ileal pouches. (1991) (159)
Prevalence of CARD15/NOD2 Mutations in Caucasian Healthy People (2007) (156)
Macrophage subpopulations in lamina propria of normal and inflamed colon and terminal ileum. (1989) (152)
Crohn's disease and pregnancy. (1984) (151)
Mapping the HLA association in Behçet's disease: a role for tumor necrosis factor polymorphisms? (2003) (149)
Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC. (2003) (145)
Detection of mRNAs for macrophage products in inflammatory bowel disease by in situ hybridisation. (1992) (143)
The relationship between inflammatory and serosal connective tissue changes in ileal Crohn's disease: evidence for a possible causative link (2000) (142)
The genetics of inflammatory bowel disease (2001) (139)
Genetic Variants of Wnt Transcription Factor TCF-4 (TCF7L2) Putative Promoter Region Are Associated with Small Intestinal Crohn's Disease (2009) (137)
Immune complexes in acute and chronic liver disease. (1978) (136)
Ulcerative colitis and persistent liver dysfunction. (1983) (135)
Immune complexes in ulcerative colitis and Crohn's disease. (1977) (133)
Preventing postoperative recurrence of Crohn's disease (1997) (133)
Effect of heparin on polymerase chain reaction (1994) (133)
Heterogeneity of HLA-DR-positive histiocytes in human intestinal lamina propria: a combined histochemical and immunohistological analysis. (1983) (131)
Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn’s disease (2005) (131)
Serum autoantibodies, ulcerative colitis and primary sclerosing cholangitis. (1986) (129)
Cytokine (TNF alpha, LT alpha and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies. (2000) (128)
Immunohistological characterisation of intraepithelial lymphocytes of the human gastrointestinal tract. (1981) (128)
Split ileostomy and ileocolostomy for Crohn's disease of the colon and ulcerative colitis: a 20 year survey. (1983) (127)
Cytokine gene polymorphisms in inflammatory bowel disease. (1996) (126)
Chronic inflammatory bowel disease, cigarette smoking, and use of oral contraceptives: findings in a large cohort study of women of childbearing age. (1986) (126)
A comparison of budesonide and mesalamine for active Crohn's disease. International Budesonide-Mesalamine Study Group. (1998) (124)
High‐Dose Methylprednisolone in the Treatment of Active Ulcerative Colitis (1988) (120)
Genetics of inflammatory bowel disease: the role of the HLA complex. (2006) (120)
T cells in peripheral blood after gluten challenge in coeliac disease (2005) (117)
Confirmation of the role of ATG16l1 as a Crohn's disease susceptibility gene (2007) (117)
Analysis of the IBD5 locus and potential gene-gene interactions in Crohn’s disease (2003) (116)
Anti-neutrophil nuclear antibody in ulcerative colitis, Crohn's disease and primary sclerosing cholangitis. (1989) (114)
The efficacy of methotrexate for maintaining remission in inflammatory bowel disease (2002) (114)
Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2). (1997) (113)
The pathogenesis of celiac disease. (1998) (112)
Intravenous cyclosporin as rescue therapy in severe ulcerative colitis: time for a reappraisal? (1998) (112)
Cigarette smoking, appendectomy, and tonsillectomy as risk factors for the development of primary sclerosing cholangitis: a case control study (2002) (111)
Olsalazine in active ulcerative colitis. (1985) (107)
TUCAN (CARD8) genetic variants and inflammatory bowel disease. (2006) (104)
Linkage analysis of candidate regions for coeliac disease genes. (1997) (101)
Long‐term results of recurrence and reoperation after strictureplasty for obstructive Crohn's disease (1995) (101)
Human keratin 8 mutations that disturb filament assembly observed in inflammatory bowel disease patients (2004) (100)
Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype (2007) (100)
A common CTLA4 haplotype associated with coeliac disease (2005) (98)
Review article: the genetics of inflammatory bowel disease. (2001) (98)
The contribution of human leucocyte antigen complex genes to disease phenotype in ulcerative colitis. (2003) (96)
The prevalence of inflammatory bowel disease in relatives of patients with Crohn's disease (1994) (94)
Immune-complex mediated colitis in rabbits. An experimental model. (1978) (92)
Small bowel gas in severe ulcerative colitis. (1991) (92)
Inhibition of leucocyte motility by drugs used in ulcerative colitis. (1981) (91)
Oral cyclosporin for chronic active Crohn's disease: a multicentre controlled trial (1994) (90)
Association of ulcerative colitis with rare VNTR alleles of the human intestinal mucin gene, MUC3. (1999) (88)
Outcome of 200 restorative proctocolectomy operations: The John Radcliffe Hospital experience (1997) (87)
Role of a defunctioning stoma in the management of large bowel Crohn's disease (2002) (86)
A functional polymorphism of the stromelysin gene (MMP-3) influences susceptibility to primary sclerosing cholangitis. (2001) (86)
Class II antigen (HLA-DR) expression by intestinal epithelial cells in inflammatory diseases of colon. (1987) (85)
Immunohistologic demonstration of abnormal colonic crypt cell kinetics in ulcerative colitis. (1985) (82)
Clinical and functional outcome after restorative proctocolectomy (1991) (82)
Recurrence After Abdominal Surgery for Crohn’s Disease (2002) (80)
Expression of HLA-DR antigens on bile duct epithelium in primary sclerosing cholangitis. (1988) (80)
The IL-23/IL-17 pathway in inflammatory bowel disease (2012) (79)
T lymphocyte subsets in inflammatory bowel disease: peripheral blood. (1983) (78)
Cyclosporin A retention enemas in refractory distal ulcerative colitis and 'pouchitis'. (1993) (78)
Cap polyposis--an unusual cause of diarrhoea. (1993) (77)
Susceptibility loci in inflammatory bowel disease (1996) (77)
Effects of the faecal stream and stasis on the ileal pouch mucosa. (1991) (77)
Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3) (2001) (77)
The prevalence, clinical features and association of HLA‐B27 in sacroiliitis associated with established Crohn’s disease (2009) (77)
Lack of association of MYO9B genetic variants with coeliac disease in a British cohort (2006) (76)
Killer Ig-like receptor (KIR) genotype and HLA ligand combinations in ulcerative colitis susceptibility (2006) (75)
Long‐term outcome after admission for acute severe ulcerative colitis in Oxford: The 1992–1993 cohort (2009) (75)
MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease (2009) (73)
Cyclosporine for induction of remission in Crohn's disease. (2005) (73)
Ten‐year experience of strictureplasty for obstructive Crohn's disease (1989) (73)
Crohn's disease: genetic susceptibility, bacteria, and innate immunity (2001) (72)
In vivo toxicity of a synthetic dodecapeptide from A gliadin in patients with coeliac disease. (1991) (71)
Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis. (2003) (69)
A study of patients with alcoholic liver disease by 31P nuclear magnetic resonance spectroscopy. (1990) (69)
NOD2 (CARD15), the first susceptibility gene for Crohn's disease (2001) (69)
Interleukin 2 receptor expression by macrophages in inflammatory bowel disease. (1988) (68)
Chronic immune colitis in rabbits. (1979) (68)
The genetics of NOD-like receptors in Crohn's disease. (2010) (68)
Slow-release 5-amino-salicylic acid (Pentasa) for the treatment of active Crohn's disease. (1990) (67)
Optimum dose of olsalazine for maintaining remission in ulcerative colitis. (1994) (66)
Infliximab use in Crohn's disease: impact on health care resources in the UK (2005) (66)
The genetics of inflammatory bowel disease. (1997) (66)
Acetylation of 5-aminosalicylic acid by isolated human colonic epithelial cells. (1990) (66)
Topics in Gastroenterology (1981) (65)
The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants. (2003) (65)
Pneumococcal infection in patients with coeliac disease (2008) (65)
The role of phagocytes in inflammatory bowel disease. (1985) (64)
A randomised trial comparing mesalazine and prednisolone foam enemas in patients with acute distal ulcerative colitis. (1996) (63)
Circulating antibodies to cow's milk proteins in ulcerative colitis (1972) (63)
Topical treatment of distal ulcerative colitis with 4-amino-salicylic acid enemas. (1984) (62)
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data (2019) (61)
The Presence of Anti‐Neutrophil Antibodies Reflects Clinical and Genetic Heterogeneity Within Inflammatory Bowel Disease (1998) (61)
Short-chain fatty acid irrigation in severe pouchitis. (1989) (61)
Cytokine gene expression in HIV‐infected intestinal mucosa (1994) (60)
Spirochaetosis of the human rectum associated with an intraepithelial mast cell and IgE plasma cell response. (1987) (60)
Salicylates for ulcerative colitis--their mode of action. (1994) (60)
Inflammatory Bowel Disease Is Linked to 19p13 and Associated with ICAM-1 (2004) (60)
Medical therapy for induction and maintenance of remission in pouchitis: a systematic review. (1999) (60)
Contribution of the IL‐2 and IL‐10 genes to inflammatory bowel disease (IBD) susceptibility (1998) (59)
Controlled trial comparing olsalazine and sulphasalazine for the maintenance treatment of ulcerative colitis. (1988) (59)
Management of acute severe colitis. (2003) (59)
The Genetic Basis of Inflammatory Bowel Disease (2009) (59)
Antagonists and non-toxic variants of the dominant wheat gliadin T cell epitope in coeliac disease (2005) (59)
Intestinal permeability in the ileal pouch. (1996) (58)
Fulminant Crohn’s colitis after allogeneic stem cell transplantation (2003) (58)
Controlled trial comparing olsalazine and sulphasalazine for the maintenance treatment of ulcerative colitis. (1988) (57)
Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease (2002) (57)
The contribution of HLA genes to IBD susceptibility and phenotype. (2004) (57)
Use of complete eluted peptide sequence data from HLA-DR and -DQ molecules to predict T cell epitopes, and the influence of the nonbinding terminal regions of ligands in epitope selection. (1998) (56)
Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1. (2004) (55)
Pharmacotherapy for inducing and maintaining remission in pouchitis. (1998) (54)
C3 metabolism in ulcerative colitis and Crohn's disease. (1977) (54)
Lymphocyte and macrophage subpopulations in pelvic ileal pouches. (1991) (54)
Inflammatory bowel disease: progress toward a gene. (2000) (53)
Single nucleotide polymorphisms in TNFSF 15 confer susceptibility to Crohn ’ s disease (2005) (52)
Oral fluticasone propionate in active distal ulcerative colitis. (1992) (52)
High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility. (2002) (51)
Olsalazine is not superior to placebo in maintaining remission of inactive Crohn's colitis and ileocolitis: a double blind, parallel, randomised, multicentre study (2001) (50)
Ulcerative enteritis. (1983) (50)
Flow cytometric analysis of peripheral blood lymphocytes in ulcerative colitis and Crohn's disease. (1991) (49)
Changing pattern of gastric cancer in Oxfordshire. (1992) (48)
Altered expression of mucins throughout the colon in ulcerative colitis. (1997) (48)
Association of a Functional Variant in the Wnt Co-Receptor LRP6 with Early Onset Ileal Crohn's Disease (2012) (48)
Immune activation during cerebellar dysfunction following Plasmodium falciparum malaria. (1992) (48)
10 Cytokines and inflammatory bowel disease (1996) (47)
Mechanism of action of 5-aminosalicylic acid and its derivatives. (1990) (47)
Ulcerative colitis and HLA phenotype. (1985) (47)
Evidence for inflammatory bowel disease of a susceptibility locus on the X chromosome. (2001) (46)
Use of an intravenous steroid regimen in the treatment of acute Crohn's disease. (1986) (46)
Factors inducing relapse in inflammatory bowel disease. (1978) (45)
Contribution of histological, serological, and genetic factors to the clinical heterogeneity of adult-onset coeliac disease (2009) (45)
Clinical and molecular characteristics of isolated colonic Crohn's disease (2008) (44)
Salicylates used in inflammatory bowel disease and colchicine impair interferon-gamma induced HLA-DR expression. (1992) (44)
Pigbel-like syndrome in a vegetarian in Oxford. (1996) (43)
Local immune mechanisms in inflammatory bowel disease and colorectal carcinoma. Natural killer cells and their activity. (1986) (43)
CELL-MEDIATED IMMUNITY TO A SYNTHETIC GLIADIN PEPTIDE RESEMBLING A SEQUENCE FROM ADENOVIRUS 12 (1987) (43)
Reaginic hypersensitivity in ulcerative colitis (1972) (42)
Peripheral blood and portal tract lymphocyte populations in primary sclerosing cholangitis. (1989) (42)
Adhesion molecule expression on vascular endothelium and nitroblue tetrazolium reducing activity in human colonic mucosa. (1995) (42)
5-Aminosalicylic acid inhibits the impaired epithelial barrier function induced by gamma interferon. (1996) (42)
Immunosuppression in the treatment of inflammatory bowel disease. II. The effects of azathioprine on lymphoid cell populations in a double blind trial in ulcerative colitis. (1976) (41)
Subclinical mucosal inflammation in diarrhea-predominant irritable bowel syndrome (IBS) in a tropical setting (2012) (40)
Humoral immune system in inflammatory bowel disease: I. Complement levels. (1977) (40)
Long-Term Function After Restorative Proctocolectomy (2005) (40)
Outcome of restorative proctocolectomy with ileal reservoir for ulcerative colitis: comparison of distal colitis with more proximal disease. (1996) (40)
Sulphasalazine and derivatives, natural killer activity and ulcerative colitis. (1985) (40)
Genome screening of coeliac disease (2002) (40)
Drug therapy of ulcerative colitis. (1992) (40)
Managing the long term care of inflammatory bowel disease patients: The cost to European health care providers. (2011) (39)
Motility of neutrophils and monocytes in Crohn's disease and ulcerative colitis. (1983) (37)
Double blind, controlled trial of 4-aminosalicylic acid and prednisolone enemas in distal ulcerative colitis. (1992) (37)
Confirmation of the novel association at the BTNL2 locus with ulcerative colitis. (2009) (36)
The pharmacogenetics of methotrexate in inflammatory bowel disease (2005) (36)
Isolation of intestinal mononuclear cells: factors released which affect lymphocyte viability and function. (1984) (36)
Medical Therapy for Induction and Maintenance of Remission in Pouchitis: A Systematic Review (1999) (36)
Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics. (2002) (36)
Cellular hypersensitivity to a synthetic dodecapeptide derived from human adenovirus 12 which resembles a sequence of A-gliadin in patients with coeliac disease. (1990) (35)
Expression of colonic antigens by goblet and columnar epithelial cells in ileal pouch mucosa: their association with inflammatory change and faecal stasis. (1994) (35)
Monocytes in inflammatory bowel disease: absolute monocyte counts. (1980) (35)
The Immunology of Ulcerative Colitis and Crohn’s Disease (1979) (35)
Recurrence and reoperation after strictureplasty for obstructive Crohn's disease: long-term results [corrected]. (1995) (34)
Pulmonary function in inflammatory bowel disease. (1978) (34)
The pharmacogenetics of methotrexate in inflammatory bowel disease. (2005) (34)
Glycosylation and sulphation of colonic mucus glycoproteins in patients with ulcerative colitis and in healthy subjects. (1993) (34)
Crypt cell proliferation and HLA-DR expression in pelvic ileal pouches. (1990) (33)
Azathioprine in Ulcerative Colitis: An Interim Report on a Controlled Therapeutic Trial (1972) (33)
HIV associated cytomegalovirus colitis as a mimic of inflammatory bowel disease. (1995) (33)
Histological features of sclerosing cholangitis in patients with chronic ulcerative colitis. (1985) (33)
Monocytes in inflammatory bowel disease: monocyte and serum lysosomal enzyme activity. (1980) (33)
Epithelial cells bearing class II molecules stimulate allogeneic human colonic intraepithelial lymphocytes. (1992) (33)
Clinical Implications of Inflammatory Bowel Disease Genetics on Phenotype (2005) (32)
Meta‐analysis using individual patient data: efficacy and durability of topical alicaforsen for the treatment of active ulcerative colitis (2013) (32)
Complement inhibitors and immunoconglutinins in ulcerative colitis and Crohn's disease. (1980) (30)
Effects of olsalazine in the jejunum of the rat. (1987) (30)
Comparison between Prospective and Retrospective Evaluation of Crohn's Disease Activity Index (2003) (30)
Serum inhibitors of leukocyte chemotaxis in Crohn's disease and ulcerative colitis. (1982) (29)
Genetics of inflammatory bowel disease. (1994) (29)
Monocytes in inflammatory bowel disease: phagocytosis and intracellular killing. (1980) (29)
Natural killer cells and spontaneous cell-mediated cytotoxicity in the human intestine. (1984) (29)
Emergence of inflammatory bowel disease 'beyond the West': do prosperity and improved hygiene have a role? (2008) (29)
Association between genetic variants in myosin IXB and Crohn's disease (2009) (29)
Exclusion of Linkage of Crohn's Disease to Previously Reported Regions on Chromosomes 12, 7, and 3 in the Belgian Population Indicates Genetic Heterogeneity (2000) (28)
CARD15 polymorphisms in Behçet's disease (2005) (28)
Two-Stage Genome-Wide Search in Inflammatory Bowel Disease: Strong Evidence for Susceptibility LOCI on Chromosomes 3, 7 and 12 (1997) (28)
Mononuclear phagocyte system of human Peyer's patches: an immunohistochemical study using monoclonal antibodies. (1989) (28)
TAP1 and TAP2 polymorphism in coeliac disease (2004) (27)
Inhibition of binding of interferon-gamma to its receptor by salicylates used in inflammatory bowel disease. (1992) (26)
IN SITU COMPARISON OF PHENOTYPICAL AND FUNCTIONAL ACTIVITY OF INFILTRATING CELLS IN ULCERATIVE COLITIS MUCOSA (1996) (25)
Gastric function and histology in chronic renal failure. (1979) (25)
Atopy in inflammatory bowel disease. (1979) (25)
MRI scanning in perianal Crohn's disease: an important diagnostic adjunct. (1999) (25)
Two‐stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease (2008) (25)
Fibrolamellar hepatocellular carcinoma complicating ulcerative colitis with primary sclerosing cholangitis. (1989) (25)
The immunology of inflammatory bowel disease. (1990) (24)
Coexpression of CD4 and CD8 on peripheral blood T cells and lamina propria T cells in inflammatory bowel disease by two colour immunofluorescence and flow cytometric analysis. (1991) (24)
DISODIUM AZODISALICYLATE IN ULCERATIVE COLITIS (1981) (23)
Yersinia colitis associated with Crohn's disease. (1985) (23)
Analysis of the CC chemokine receptor 5 (CCR5) Delta32 polymorphism in Behçet's disease. (2004) (23)
Ulcerative colitis and sarcoidosis. (1986) (23)
Primary sclerosing cholangitis--an immunologically mediated disease? (1985) (22)
The humoral immune system in inflammatory bowel disease (1978) (22)
Two-color immunofluorescence and flow cytometric analysis of peripheral blood lymphocyte subsets in Caucasian and Japanese healthy subjects. (1991) (22)
Characterisation and quantification of mucosal cytokine that induces epithelial histocompatibility locus antigen-DR expression in inflammatory bowel disease. (1992) (22)
Acute inflammation in ideal pouches(pouchitis) (1991) (22)
Selective IgA deficiency and Crohn's disease: report of two cases. (1977) (22)
Immunoglobulin production by isolated intestinal mononuclear cells from patients with ulcerative colitis and Crohn's disease. (1989) (22)
Genotype‐based phenotyping heralds a new taxonomy for inflammatory bowel disease (2003) (21)
Local immune mechanisms in inflammatory bowel disease and colorectal carcinoma (1986) (21)
Comparison of 5-aminosalicylic acid and N-acetylaminosalicylic acid uptake by the isolated human colonic epithelial cell. (1992) (21)
Olsalazine in patients intolerant of sulphasalazine. (1987) (20)
The mononuclear cells of human mesenteric blood, intestinal mucosa and mesenteric lymph nodes: compartmentalization of NK cells. (1984) (20)
Medical management of severe ulcerative colitis (1988) (20)
IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis. (2006) (19)
HETEROGENEOUS EXPRESSION OF CARCINOEMBRYONIC ANTIGEN IN THE NORMAL COLON AND UPREGULATION IN ACTIVE ULCERATIVE COLITIS (1996) (19)
Functional and biochemical subtypes of the haplotype HLA-DR3 in patients with celiac disease or idiopathic membranous nephropathy. (1987) (19)
Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohn's disease (2012) (19)
Connective tissue changes in Ileal crohn's disease: Relationship to disease phenotype and ulcer-associated cell lineage (2001) (19)
HLA genes are important phenotype determining genes in the peripheral arthropathies of inflammatory bowel disease (IBD) (1998) (18)
Analysis of the IBD 5 locus and potential gene-gene interactions in Crohn ’ s disease (2003) (18)
Immunoregulatory mechanisms in nonspecific inflammatory bowel disease. (1983) (17)
Therapy Insight: pyoderma gangrenosum—old disease, new management (2005) (17)
W1223 Genetic Factors Conferring an Increased Susceptibility to Develop Crohn's Disease Also Influence Disease Phenotype, but Do Not Predict it. Results From the IBDChip European Project (2010) (17)
In vitro model for the assessment of luminal factors on rectal mucosa. (1983) (17)
Carbenoxolone (duogastrone) and cimetidine in the treatment of duodenal ulcer--a therapeutic trial. (1980) (16)
Azathioprine in ulcerative colitis. (1972) (16)
The nature of the natural killer (NK) cell of human intestinal mucosa and mesenteric lymph node. (1985) (16)
Transient, selective factor X deficiency and acute liver failure following chest infection treated with erythromycin BP. (1983) (16)
Clinical Gastrointestinal Immunology (1979) (15)
Factors affecting the spontaneous cell-mediated cytotoxicity of intestinal mononuclear cells. (1984) (15)
Site of action of platelet-activating factor within the mucosa of rabbit distal colon. (1995) (15)
Inflammatory bowel disease is associated with a functional TNF polymorphism that affects an OCT1/NF-KB transcription factor interaction (2002) (15)
Two-color immunofluorescence and flow cytometric analysis of lamina propria lymphocyte subsets in ulcerative colitis and Crohn's Disease (1991) (15)
Budesonide and mesalazine in active Crohn's disease: a comparison of the effects on quality of life (2002) (15)
Immunology of inflammatory bowel disease. (1987) (15)
Colitis: Diagnosis and Therapeutic Strategies (2006) (15)
A locus telomeric toHLA-DPB encodes susceptibility to coeliac disease (2006) (15)
Clq metabolism in ulcerative colitis and Crohn's disease. (1979) (15)
Sacroiliac joint uptake ratios in inflammatory bowel disease: relationship to back pain and to activity of bowel disease. (1982) (14)
Ulcerative colitis (1992) (14)
Production of epithelial cell growth factors by lamina propria mononuclear cells. (1992) (14)
Lactulose hydrogen breath test in the diagnosis of bacterial overgrowth. (1990) (14)
Subcellular localisation of vitamin B12 during absorption in the guinea-pig ileum. (1981) (14)
Inhibition of leucocyte motility and prevention of immune-complex experimental colitis by hydroxychloroquine. (1982) (13)
Acquired double pylorus. (1978) (13)
Human colonic intraepithelial lymphocytes suppress in vitro immunoglobulin synthesis by autologous peripheral blood lymphocytes and lamina propria lymphocytes. (1993) (13)
Genotype-phenotype analysis of the Crohn’s disease susceptibility haplotype on chromosome 5q31 (2003) (13)
Risks and benefits of azathioprine therapy (2005) (13)
A randomized, double-blind, placebo-controlled trial of olsalazine for active Crohn's disease. (1995) (12)
The diagnosis of the site of upper gastrointestinal haemorrhage in patients with established portal hypertension. (1977) (12)
Association of caspase-9 and RUNX3 with inflammatory bowel disease. (2011) (12)
Inflammatory Disease of the Bowel (1980) (12)
The role of platelet-activating factor in the pathogenesis of gastrointestinal disease. (1994) (11)
Cytokines and inflammatory bowel disease. (1996) (11)
Smoking benefits celiac sprue and pouchitis: implications for nicotine therapy? (1997) (11)
Retinal periphlebitis in ulcerative colitis. (1990) (11)
Effect of human intestinal macrophages on immunoglobulin production by human intestinal mononuclear cells isolated from patients with inflammatory bowel disease (1990) (11)
Regional differences in the response to platelet-activating factor in rabbit colon. (1992) (11)
Alpha-chain disease diagnosed by rectal biopsy. (1980) (11)
Sulfasalazine-induced impotence: a beneficial resolution with olsalazine? (1989) (11)
Studies on monocytes in inflammatory bowel disease: factors influencing monocyte lysosomal enzyme activity. (1980) (11)
Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine — A 30 year study (2000) (10)
Advances in mucosal immunology. (1997) (10)
Macrophage and lymphocyte subpopulations in magnifying endoscopic lesions of Crohn's disease. (1988) (10)
Exclusion of linkage of Crohn's disease to previously reported regions on chromosomes 12, 7, and 3 in the Belgian population indicates genetic heterogeneity. (2000) (10)
Cellular hypersensitivity to gluten derived peptides in coeliac disease. (1987) (10)
Colonic bacterial proteases to IgA1 and sIgA in patients with ulcerative colitis. (1987) (10)
Genetics of Inflammatory Bowel Disease. A Personal View on Progress and Prospects (1998) (10)
Precision mapping of chromosome 12 linkage in IBD: Evidence for a haplotype association (1998) (9)
Mapping susceptibility loci in inflammatory bowel disease: why and how? (1997) (9)
Microscopic colitis: can it be qualitatively and quantitatively characterized? (1992) (9)
Tumour related inhibition of macrophage chemotaxis in patients with colon cancer. (1987) (9)
The management of acute severe ulcerative colitis. (1991) (9)
SPLENIC PHAGOCYTIC FUNCTION IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE (1981) (9)
Response to treatment of microscopic colitis. (1994) (9)
Salicylates for inflammatory bowel disease. (1994) (9)
Primary antibody deficiency and Crohn's disease (1999) (9)
Endocrine function after cimetidine. (1979) (8)
Novel presentation of coeliac disease after following the Atkins’ low carbohydrate diet (2005) (8)
Lymphocyte Subpopulations in Volunteers taking Olsalazine (1988) (8)
CCR5Δ32 polymorphism in inflammatory bowel disease: Further association with ulcerative colitis and with primary sclerosing cholangitis (2000) (8)
Cold-reactive lymphocytotoxins in Crohn's disease and ulcerative colitis. I. Incidence and characterization. (1982) (8)
Budesonide and mesalazine in active Crohn's disease: a comparison of the effects on quality of life. (2002) (8)
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Side effects of azathioprine treatment given for inflammatory bowel disease-a 30 year audit (2000) (7)
Do HLA antigens predict the occurrence of extraintestinal manifestations of IBD? (2008) (7)
Serumautoantibodies, ulcerative colitis andprimary sclerosing cholangitis (1986) (7)
ALTERED EXPRESSION OF TGFα AND TGFβ1 IN THE MUCOSA OF THE FUNCTIONING PELVIC ILEAL POUCH (1996) (7)
Immune Complexes in Inflammatory Bowel Disease (1976) (7)
Ileal pouch dialysate is cytotoxic to epithelial cell lines, but not to CaCo-2 monolayers. (1997) (7)
Amplification of toll-like receptor sensitivity by muramyl dipeptide is impaired in crohn's disease associated NOD2 mutations. (2005) (7)
Autoimmune and inflammatory diseases of the gastrointestinal tract (1976) (7)
Transmission disequilibrium testing confirms the association of the TNFα 1031C allele with Crohn's disease (2001) (7)
Recent advances in mucosal immunity (1983) (7)
Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease. (2002) (7)
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Respiratory burst capacity of human intestinal macrophage subpopulations (1990) (7)
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Ulcerative colitis and Crohn's disease—susceptibility genes and clinical patterns (1998) (6)
The immunology of inflammatory bowel disease (1990) (6)
Antigen induced suppression in peripheral blood and lamina propria mononuclear cells in inflammatory bowel disease. (1992) (6)
Alpha 1-antitrypsin serum concentration and phenotypes in ulcerative colitis. (1984) (6)
Antigenic reactivity of peptides derived from wheat gluten with sera from patients with coeliac disease. (1985) (6)
Clinical features of erythema nodosum (EN) and uveitis associated with inflammatory bowel disease (IBD) (2000) (6)
Gastrointestinal amyloidosis complicating psoriatic arthropathy (1981) (6)
Are cytokine gene polymorphisms important in the pathogenesis of inflammatory bowel disease? (1996) (6)
Evidence for separate disease phenotypes in intestinal Crohn's disease. (2002) (6)
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Infliximab for ulcerative colitis. (2002) (5)
Preliminary Characterisation of Leucocyte Migration Inhibition Factor (LIF) Produced by Lymphocytes from Coeliac Patients When Stimulated with Gluten Peptides (1987) (5)
Extraintestinal manifestations of inflammatory bowel disease (IBD) and polymorphisms in the TNFα gene: Further evidence for phenotype determining genes in the MHC region on chromosome 6 (2001) (5)
Calcium intakes in patients with coeliac disease and inflammatory bowel disease: are they meeting British Society of Gastroenterology guidelines? (2006) (5)
Tlymphocyte subsets ininflammatory boweldisease: peripheral blood (1983) (5)
GENETIC MARKERS IN INFLAMMATORY BOWEL DISEASE (1996) (5)
Coeliac Disease: Possible Mannose-Specific Lectin Activity of Gluten (1985) (5)
Fine mapping a susceptibility locus on the X chromosome in the Belgian population in inflammatory bowel disease (IBD) (1999) (4)
Alpha 2-macroglobulin in patients with inflammatory bowel disease. (1980) (4)
Cimetidine and cerebral blood flow in elderly patients. (1981) (4)
Current Topics in Immunology Series (1978) (4)
Proceedings: Immune complexes in ulcerative colitis--an experimental model. (1976) (4)
Induction of HLA-DR Molecules on a Colonic Epithelial Cell Line by γ-Interferon (γ-IFN) (1988) (4)
Diagnosis and medical treatment of ulcerative colitis. (1982) (4)
Identification of HIV-1 viral RNA in intestinal tissue from patients with early and late HIV infection. (1996) (4)
Vitamin D receptor gene polmorphism further evidence for an association with Crohn's disease (1998) (4)
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Mechanisms of carrageenan injury of cell monolayers. (1989) (4)
Carnitine as a possible adjunct in parenteral feeding. (1984) (4)
Benign intracranial hypertension and ulcerative colitis (1972) (4)
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Conditions of the Eyes and Joints Associated with Inflammatory Bowel Disease (2010) (4)
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A Randomized, Double‐Blind, Placebo‐Controlled Trial of Olsalazine for Active Crohn's Disease (1995) (3)
Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis (1994) (3)
Phenotypic characterization of isolated intraepithelial lymphocytes in patients with ulcerative colitis and normal controls (1992) (3)
Cytokine Profiles in HIV Infected Intestinal Mucosa (1993) (3)
The preparation of human intrinsic factor-cobalamin complex from human gastric juice by immunoadsorption. (1984) (3)
Clinical immunology of the liver and gastrointestinal tract (1987) (3)
OUTPATIENT PREPARATION FOR COLONOSCOPY (1981) (3)
Altered expression of TGF alpha and TGF beta 1 in the mucosa of the functioning pelvic ileal pouch. (1996) (3)
A revised sequence of the human β7 integrin gene (ITGB7) promoter region obtained by inverse PCR (2000) (3)
Irritable bowel syndrome: is a barium enema necessary? (1986) (3)
Challenges in inflammatory bowel disease (2006) (3)
A Method for Investigating the Effects of Drugs on the Prostaglandin Synthetase of Single Rectal Biopsies (1981) (3)
The Role of Cytokines in Inflammatory Bowel Disease (1994) (3)
Cytokine gene transcription of human colonic intraepithelial lymphocytes costimulated with epithelial cells bearing HLA-DR and its inhibition by 5-aminosalicylic acid (1996) (3)
60 P The 5q31/IBD5 risk haplotype is associated with overall susceptibility to Crohn's disease and determines perianal phenotype (2002) (3)
Immunoglobulin production byisolated intestinal mononuclear cells frompatients withulcerative colitis andCrohn's disease (1989) (3)
The immunology of coeliac disease (2004) (3)
Intestinal mucosal abnormality associated with human immunodeficiency virus infection (1994) (3)
No evidence for linkage on chromosomes 16-12-7 and 3 in the belgian population may reflect genetic heterogeneity of inflammatory bowel disease (1998) (3)
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MONOCYTE ACID HYDROLASES IN INFLAMMATORY BOWEL DISEASE (1978) (2)
Polymorphism at position-1031 in the TNF gene confers susceptibility to Crohn's disease (2000) (2)
The Immunology of Celiac Disease (1992) (2)
Prevalence of sacroiliitis in Crohn's disease, and its correlation with clinical, radiologic and genotypic parameters (2002) (2)
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E rosetting lymphocytes in inflammatory bowel disease. An analysis using monoclonal antibodies. (1983) (2)
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Innate immunogenetics and nflammatory bowel disease (IBD) (2003) (2)
Novel polymorphisms in the beta 7 integrin gene (ITGB7): Family based association studies in IBD (2001) (2)
Association of small intestinal diverticulosis with chronic pancreatitis leading to severe malabsorption. Report of three cases. (1988) (2)
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Interleukin-23R arg381 gln is associated with susceptibility to Crohn's disease but not with phenotype in an Italian population - Reply (2007) (2)
Detection of 5-Aminosalicylic Acid (5-ASA) in Rectal Mucosal Biopsies (1987) (2)
Polymorphisms in the MEP1A Gene: A Role in IBD? (2006) (2)
Peripheral blood T cells induced by gluten challenge in coeliac disease target a specific molecular motif and express a gut-homing integrin (2001) (2)
Family based association studies of STAT6, a positional candidate gene for IBD (2001) (2)
T1243 NOD2 Activation By Muramyl Dipeptide Induces Autophagy in Dendritic Cells in An ATG16l1 Dependent Pathway (2008) (2)
Monocyte Activity in Crohn's Disease and Ulcerative Colitis (1978) (1)
The Fate of 125Iodine-Labelled Intrinsic Factor During 57Co-Cyanocobalamin Absorption (1984) (1)
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Celiac disease associated with HLA-DQ8 and DQ2 have different T-cell repertoires in vivo (2003) (1)
Allelic variants of thiopurine methyl transferase are associated with azathioprine induced leukopaenia (2000) (1)
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Serum Concentrations of Complement Inhibitors and Immunoconglutinins in Inflammatory Bowel Disease (1979) (1)
Monocyte Function in Crohn’s Disease (1981) (1)
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Discordant sibling pair linkage analysis provides further support for the chromosome 12 inflammatory bowel disease susceptibility locus (2000) (1)
Effect of Acute Infusion of Cimetidine on Cerebral Blood Flow (1979) (1)
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Immunology of the Gastrointestinal Tract and Liver (1989) (1)
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Macrophage andlymphocyte subpopulations inmagnifying endoscopic lesions ofCrohn's disease (1988) (1)
HLA class II genes in ulcerative colitis: Strong evidence for a relationship between genotype and clinical phenotype (1995) (1)
Calcium intakes and osteoporosis screening in patients with coeliac disease, crohn's disease and ulcerative colitis (2008) (1)
The intercellular adhesion molecule-1 polymorphisms in IBD (2002) (1)
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Correction for Ahmad et al, The molecular classification of the clinical manifestations of Crohn's disease (2003) (1)
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Tumourrelated inhibition ofmacrophage chemotaxis inpatients withcolon cancer (1987) (0)
Modulation of Intestinal Nk Activity (1984) (0)
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No association between Nod2 polymorphisms and susceptibility to, or progression of, primary sclerosing cholangitis (2002) (0)
Comparison of outcome following ileal pouch anal anastomosis for distal and total ulcerative colitis (1995) (0)
therapeutic epitopes and their uses (2003) (0)
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S1180 Crohn's Disease Is Associated with a Specific Urinary Metabolic Profile (2008) (0)
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M1032 Managing the Long Term Care of Inflammatory Bowel Disease Patients: the Cost to European Health Care Providers (2010) (0)
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S1681 Investigation of NOD2 Signaling in Dendritic Cells (2009) (0)
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Reply (1991) (0)
Subclinical intestinal mucosal inflammation in diarrhoea predominant irritable bowel syndrome in a tropical setting (2010) (0)
Liver and biliary Expression of HLA-DR antigens on bile duct epithelium in primary sclerosing cholangitis (2006) (0)
A two-stage association study between inflammatory bowel disease and polymorphisms spanning GNAI2 (2001) (0)
The PLA2G2A gene shows no major influence in the genetic susceptibility of IBD (2007) (0)
Crypt Cell Proliferation (CCP) Hla-Dr Expression and Intra Epithelial Lymphocytes (IEL) in Pelvic Ileal Pouches (1990) (0)
NITRIC OXIDE IN ULCERATIVE COLITIS. AUTHORS' REPLY (1995) (0)
T1824 Sub Clinical Intestinal Mucosal Inflammation in Diarrhea Predominant Irritable Bowel Syndrome (IBS) in a Tropical Setting (2010) (0)
M1129 Does the Clinical Phenotype of Inflammatory Bowel Disease Differ Between Caucasian and South Asian Patients Living in the UK (2009) (0)
96 The Wnt Co-Receptor LRP6 as a New Factor in Ileal Crohn's Disease (2012) (0)
Thank you to reviewers (2021) (0)
Polymorphisms in the MEP1A Gene: A Role in Inflammatory Bowel Disease (IBD)? (2004) (0)
A replication study of the inflammatory bowel disease region on 6p. (2000) (0)
DP ALLELES DO NOT INDEPENDENTLY CONFER SUSCEPTIBILITY TO CELIAC-DISEASE (1989) (0)
Mucus Production and Its Sulphation in the Normal Colonic Mucosa and in Patients with Left-Sided Ulcerative Colitis (UC) (1990) (0)
FUTURE DIRECTIONS FOR IMMUNOLOGICAL RESEARCH (1986) (0)

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