D. Philip Jones
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D. Philip Jonesbiology Degrees
Biology
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Cell Biology
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Biochemistry
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Biology
D. Philip Jones's Degrees
- PhD Biochemistry Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)D. Philip Jones's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mitochondrial control of apoptosis: the role of cytochrome c. (1998) (712)
- Redox state of glutathione in human plasma. (2000) (550)
- Presence of a pre‐apoptotic complex of pro‐caspase‐3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells (1999) (542)
- EFFECTS OF PROLONGED ETHANOL INTAKE: PRODUCTION OF FATTY LIVER DESPITE ADEQUATE DIETS. (1965) (533)
- Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC. (1998) (465)
- Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes. (1998) (464)
- Glutathione-dependent protection against oxidative injury. (1990) (408)
- Glutathione redox potential in response to differentiation and enzyme inducers. (1999) (333)
- Metabolism of hydrogen peroxide in isolated hepatocytes: relative contributions of catalase and glutathione peroxidase in decomposition of endogenously generated H2O2. (1981) (329)
- Compartmentation of glutathione: implications for the study of toxicity and disease. (1996) (323)
- Interrelation of uric acid and ethanol metabolism in man. (1962) (275)
- Apoptosis: molecular control point in toxicity. (1994) (272)
- Intracellular diffusion gradients of O2 and ATP. (1986) (251)
- Redox compartmentalization and cellular stress (2010) (220)
- Distribution of oxidized and reduced forms of glutathione and cysteine in rat plasma. (1985) (183)
- Mitochondrial transmembrane potential and pH gradient during anoxia. (1987) (174)
- Gradients of O2 concentration in hepatocytes. (1978) (174)
- Exogenous glutathione protects intestinal epithelial cells from oxidative injury. (1986) (172)
- Plasma antioxidant status after high-dose chemotherapy: a randomized trial of parenteral nutrition in bone marrow transplantation patients. (2000) (166)
- Glutathione in foods listed in the National Cancer Institute's Health Habits and History Food Frequency Questionnaire. (1992) (166)
- Inhibition of ATP-dependent microsomal Ca2+ sequestration during oxidative stress and its prevention by glutathione. (1983) (164)
- Renal glutathione transport. Characteristics of the sodium-dependent system in the basal-lateral membrane. (1984) (163)
- Glutathione uptake and protection against oxidative injury in isolated kidney cells. (1988) (157)
- Use of isolated kidney cells for study of drug metabolism. (1979) (157)
- Protection against paraquat-induced injury by exogenous GSH in pulmonary alveolar type II cells. (1986) (149)
- Detoxification reactions in isolated hepatocytes. Role of glutathione peroxidase, catalase, and formaldehyde dehydrogenase in reactions relating to N-demethylation by the cytochrome P-450 system. (1978) (135)
- The taurine transporter: mechanisms of regulation (2006) (130)
- Metabolism of glutathione and a glutathione conjugate by isolated kidney cells. (1979) (125)
- Glutathione oxidation is associated with altered microtubule function and disrupted fertilization in mature hamster oocytes. (1997) (123)
- Hypoxia and drug metabolism. (1981) (122)
- Diet and apoptosis. (2003) (122)
- Effects of N-acetyl-L-cysteine on T-cell apoptosis are not mediated by increased cellular glutathione. (1995) (103)
- Oxygen dependence of oxidative stress. Rate of NADPH supply for maintaining the GSH pool during hypoxia. (1990) (103)
- Oral glutathione increases tissue glutathione in vivo. (1991) (101)
- Intracellular oxygen supply during hypoxia. (1982) (100)
- Detection of pro‐caspase‐3 in cytosol and mitochondria of various tissues (1998) (94)
- ATP concentration gradients in cytosol of liver cells during hypoxia. (1985) (94)
- Bioavailability of dietary glutathione: effect on plasma concentration. (1990) (92)
- Effect of mitochondrial clustering on O2 supply in hepatocytes. (1984) (91)
- Oxidant-induced apoptosis in cultured human retinal pigment epithelial cells. (1999) (89)
- Oxygen dependence of mitochondrial function in isolated rat cardiac myocytes. (1986) (88)
- Dietary compounds that induce cancer preventive phase 2 enzymes activate apoptosis at comparable doses in HT29 colon carcinoma cells. (1999) (87)
- Protection of retinal pigment epithelium from oxidative injury by glutathione and precursors. (1993) (85)
- Selective depletion of mitochondrial glutathione concentrations by (R,S)-3-hydroxy-4-pentenoate potentiates oxidative cell death. (1993) (84)
- Effect of dietary inducer dimethylfumarate on glutathione in cultured human retinal pigment epithelial cells. (1999) (83)
- Rotenone-induced G2/M cell cycle arrest and apoptosis in a human B lymphoma cell line PW. (2001) (83)
- Renal metabolism during normoxia, hypoxia, and ischemic injury. (1986) (82)
- Transport of glutathione by renal basal-lateral membrane vesicles. (1983) (81)
- Uptake of the glutathione conjugate S-(1,2-dichlorovinyl)glutathione by renal basal-lateral membrane vesicles and isolated kidney cells. (1985) (80)
- Plasma total glutathione in humans and its association with demographic and health-related factors (1993) (80)
- Secondary bioenergetic hypoxia. Inhibition of sulfation and glucuronidation reactions in isolated hepatocytes at low O2 concentration. (1982) (79)
- EFFECTS OF ETHANOL ON PLASMA LIPIDS IN MAN. (1963) (79)
- Fate of dietary glutathione: disposition in the gastrointestinal tract. (1990) (77)
- Transepithelial transport of glutathione in vascularly perfused small intestine of rat. (1987) (74)
- Mitochondrial transmembrane ion distribution during anoxia. (1987) (72)
- Impact of nutrients on cellular lipid peroxidation and antioxidant defense system. (1995) (70)
- Dietary glutathione intake in humans and the relationship between intake and plasma total glutathione level. (1994) (67)
- Variability in glutathione-dependent detoxication in vivo and its relevance to detoxication of chemical mixtures. (1995) (66)
- Formation and metabolism of a glutathione-S-conjugate in isolated rat liver and kidney cells. (1978) (66)
- Mitochondria-mediated cell injury. Symposium overview. (1997) (64)
- Suppression of mitochondrial respiratory function after short-term anoxia. (1987) (63)
- Characteristics of glutathione biosynthesis by freshly isolated rat kidney cells. (1980) (63)
- Use of digitonin fractionation to determine mitochondrial transmembrane ion distribution in cells during anoxia. (1985) (60)
- Functions of Glutathione in Drug Metabolism (1978) (58)
- Separation of cytochrome c-dependent caspase activation from thiol-disulfide redox change in cells lacking mitochondrial DNA. (2000) (57)
- Adaptive regulation of taurine transport in two continuous renal epithelial cell lines. (1990) (56)
- Intracellular O2 gradients in cardiac myocytes. Lack of a role for myoglobin in facilitation of intracellular O2 diffusion. (1982) (56)
- Keratinocyte growth factor enhances glutathione redox state in rat intestinal mucosa during nutritional repletion. (1999) (55)
- Dietary glutathione intake and the risk of oral and pharyngeal cancer. (1994) (55)
- Use of exogenous glutathione for metabolism of peroxidized methyl linoleate in rat small intestine. (1990) (53)
- Effect of hypoxia on tert-butylhydroperoxide-induced oxidative injury in hepatocytes. (1988) (53)
- Nutrient supply and mitochondrial function. (1989) (50)
- Drug metabolism and toxicity during hypoxia. (1989) (49)
- Control of glucuronidation during hypoxia. Limitation by UDP-glucose pyrophosphorylase. (1984) (49)
- Development of tubular function. (1992) (49)
- Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis. (2001) (49)
- Secretion of cysteine and glutathione from mucosa to lumen in rat small intestine. (1994) (49)
- On the existence of peroxocarbonates in aqueous solution (1986) (48)
- Oxygen dependence of glutathione synthesis in hepatocytes. (1989) (48)
- Rat jejunum controls luminal thiol-disulfide redox. (2000) (48)
- Regulation of taurine transporter activity in LLC-PK1 cells: role of protein synthesis and protein kinase C activation. (1991) (47)
- Synthesis and transport of glutathione by cultured human retinal pigment epithelial cells. (1994) (46)
- Fas mediates apoptosis and oxidant-induced cell death in cultured hRPE cells. (2000) (45)
- Glutathione S-transferase in mucus of rat small intestine. (2000) (45)
- Effect of chronic hypoxia on detoxication enzymes in rat liver. (1992) (44)
- Uptake of riboflavin by isolated rat liver cells. (1983) (44)
- Calcium- and phosphate-dependent release and loading of glutathione by liver mitochondria. (1991) (43)
- Interactions between nutrients and peptide growth factors in intestinal growth, repair, and function. (1999) (41)
- Intracellular catalase function: analysis of the catalatic activity by product formation in isolated liver cells. (1982) (40)
- Glutathione transport by type II cells in perfused rat lung. (1994) (40)
- Hemoprotein quantitation in isolated hepatocytes. (1979) (39)
- Oxygen dependence of adrenal cortex cholesterol side chain cleavage. Implications in the rate-limiting steps in steroidogenesis. (1984) (38)
- Alkali-metal peroxocarbonates, M2[CO3]·nH2O2, M2[C2O6], M[HCO4]·nH2O, and Li2[CO4]·H2O (1980) (37)
- Biomarkers of oxidative stress study: are plasma antioxidants markers of CCl(4) poisoning? (2000) (37)
- Serum cholesterol esterifying and cholesteryl ester hydrolyzing activities in liver diseases: relationships to cholesterol, bilirubin, and bile salt concentrations. (1971) (36)
- Renal toxicity of cancer chemotherapeutic agents in children: ifosfamide and cisplatin. (1995) (35)
- Glutathione protection in alveolar type II cells from fetal and neonatal rabbits. (1992) (33)
- Polarity of taurine transport in cultured renal epithelial cell lines: LLC-PK1 and MDCK. (1993) (33)
- Alanylglutamine dipeptide and growth hormone maintain PepT1-mediated transport in oxidatively stressed Caco-2 cells. (2005) (33)
- Analysis of intracellular oxygenation of isolated adult cardiac myocytes. (1986) (32)
- Preparation and characteristics of isolated kidney cells. (1981) (32)
- Cyanide toxicity in hepatocytes under aerobic and anaerobic conditions. (1989) (31)
- Abnormal metabolism of S-adenosyl-L-methionine in hypoxic rat liver. Similarities to its abnormal metabolism in alcoholic cirrhosis. (1994) (31)
- Effect of chronic hypoxia on acetaminophen metabolism in the rat. (1991) (31)
- Effects of insulin on triglyceride and free fatty acid metabolism in man. (1965) (30)
- Quantitation of hemoproteins in rat small intestinal mucosa with identification of mitochondrial cytochrome P-450. (1980) (29)
- Hepatic function in rats after spaceflight: effects on lipids, glycogen, and enzymes. (1987) (28)
- Postanoxic oxidative injury in rat hepatocytes: lactate-dependent protection against tert-butylhydroperoxide. (1992) (26)
- X-Ray crystal structure of the industrial bleaching agent ‘sodium percarbonate’[sodium carbonate–hydrogen peroxide (2/3)] (1977) (25)
- Determinants of mitochondrial O2 dependence in kidney. (1987) (25)
- Enteral nutrition and keratinocyte growth factor regulate expression of glutathione-related enzyme messenger RNAs in rat intestine. (2000) (24)
- Free fatty acid turnover and triglyceride metabolism after ethanol ingestion in man. (1965) (24)
- Revascularization for acute regional infarct: superior protection with warm blood cardioplegia. (1993) (23)
- Mitochondrial dysfunction during anoxia and acute cell injury. (1995) (22)
- Characteristics of taurine transport in cultured renal epithelial cell lines: asymmetric polarity of proximal and distal cell lines. (1992) (21)
- Influences of dietary fat on alcoholic fatty liver. (1966) (21)
- Effect of hypoxia on hepatic DNA methylation and tRNA methyltransferase in rat: similarities to effects of methyl-deficient diets. (1996) (20)
- An in vivo examination of rat brain during sepsis with 31P-NMR spectroscopy. (1989) (20)
- Purification and properties of the membranal thiol oxidase from porcine kidney. (1986) (20)
- Direct determination of UDP-glucuronic acid in cell extracts by high-performance liquid chromatography. (1982) (19)
- GSH transport and GSH-dependent detoxication in small intestine of rats exposed in vivo to hypoxia. (1996) (19)
- Localization of the membrane-associated thiol oxidase of rat kidney to the basal-lateral plasma membrane. (1982) (19)
- Coordinated multisite regulation of cellular energy metabolism. (1992) (19)
- Hypercysteinemia and delayed sulfur excretion in cirrhotics after oral cysteine loads. (1989) (19)
- Correlation of H2O2 production and liver catalase during riboflavin deficiency and repletion in mammals. (1983) (18)
- Characterization of the membrane-associated thiol oxidase activity of rat small-intestinal epithelium. (1983) (18)
- Characteristics of cysteine uptake in intestinal basolateral membrane vesicles. (1984) (17)
- Clearance of glutathione disulfide from rat mesenteric vasculature. (1994) (15)
- Benzylamine metabolism at low O2 concentrations. Relative sensitivities of monoamine oxidase, aldehyde dehydrogenase and hippurate synthesis to hypoxia. (1984) (15)
- Protein Interferes with Ionised Calcium Measurement at the Reference Electrode Liquid Junction (1987) (15)
- Metabolic hypoxia: accumulation of tyrosine metabolites in hepatocytes at low pO2. (1978) (14)
- Effects of glucose, sucrose, and lactose on intestinal disaccharidases in the rat. (1972) (14)
- Intracellular inhibition of UDP-glucose dehydrogenase during ethanol oxidation. (1983) (13)
- Conversion of catalase to the secondary catalase-peroxide complex (compound II) by alpha-methyldopa. (1981) (11)
- Regulation of expression of taurine transport in two continuous renal epithelial cell lines and inhibition of taurine transporter by a site-directed antibody. (1996) (11)
- Fractionation and analysis of mitochondria with polycarbonate membrane filters. (1989) (10)
- Protective effect of the dimer of 16,16-diMePGB1 against KCN-induced mitochondrial failure in hepatocytes. (1992) (10)
- Meso‐ionic compounds of the s‐triazole series (1965) (10)
- Oxygen dependence of oestrogen production by human placental microsomes and cultured choriocarcinoma cells. (1985) (9)
- Regulation of microsomal stearoyl-coenzyme A desaturase. Purification of a non-substrate-binding protein that stimulates activity. (1979) (9)
- Islet Secretory Granules Contain Cytochrome b561 (1986) (8)
- Apparatus for automatically maintaining cell suspension at low, constant oxygen concentrations: the oxystat. (1978) (7)
- Epitope mapping using histidine-tagged protein fragments: application to Escherichia coli RNA polymerase sigma 70. (1996) (7)
- Effect of calcium ions on ethanol oxidation and drug glucuronidation in isolated hepatocytes. (1979) (7)
- Defining the resistance to oxygen transfer in tissue hypoxia (1990) (7)
- Hepatic enzyme adaptation in rats after space flight. (1985) (7)
- Regulation of taurine transport by external taurine concentration and medium osmolality in renal tubular cells in culture. (1994) (6)
- Clustering of serum calcium and magnesium concentrations in siblings. (1986) (6)
- Ascorbate deficiency and oxidative stress in the alveolar type II cell. (1997) (5)
- Acute acetaminophen toxicity in transgenic mice with elevated hepatic glutathione. (2000) (5)
- Protection of hepatocytes against death due to mitochondrial failure: effect of di-Calciphor on antimycin A-induced toxicity. (1994) (5)
- Studies on the vibrational spectra of perhydrates—I. Spectra of normal and isotopically substituted (2H, 13C) alkali metal oxalate perhydrates, MI2C2O4·H2O2 (1980) (5)
- ALKALI METAL PEROXOCARBONATES, M2(CO3).NH2O2, M2(C2O6), M(HCO4).NH2O, AND LI2(CO4).H2O (1981) (3)
- Intracellular inhibition of catalase by alpha-methyldopa. (1981) (2)
- Biochemical and molecular characterization of variant pyruvate kinase enzymes and genes from three patients with red blood cell pyruvate kinase deficiency. (1991) (1)
- Polarized nature of taurine transport in LLC-PK1 and MDCK cells: Further characterization of divergent transport models (1993) (1)
- Intracellular Oxygen Supply: Implications for Intensive Care (1991) (1)
- The Synthesis and Dilute Solution Properties of Styrene-Siloxane ABA Block Copolymers (1971) (0)
- Metabolic changes detected by in vivo proton magnetic resonance spectroscopy in the striatum of rats treated with alteration of dietary sulfur amino acids content (2009) (0)
- TCA cycle remodeling is associated with IL-1β-mediated proinflammatory eicosanoid signaling in humans with pulmonary tuberculosis (2021) (0)
- Protective effect of dicalciphor during mitochondrial failure. (1992) (0)
- Transepithelial transport of glutathione in isolated perfused small intestine (1986) (0)
- X-RAY CRYSTAL STRUCTURE OF THE INDUSTRIAL BLEACHING AGENT ′SODIUM PERCARBONATE′ (SODIUM CARBONATE-HYDROGEN PEROXIDE (2 3)) (1978) (0)
- Comparative evaluation of a Technicon SMAC2/RA1000 System with an American Monitor Parallel during normal service work (1986) (0)
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