D. E. Royston

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D. E. Royston

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#13495

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#8378

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Philosophy

D. E. Royston's Degrees

Doctorate Medicine Harvard University

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D. E. Royston's Published Works

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Published Works

EFFECT OF APROTININ ON NEED FOR BLOOD TRANSFUSION AFTER REPEAT OPEN-HEART SURGERY (1987) (642)
Reduction in blood loss and blood use after cardiopulmonary bypass with high dose aprotinin (Trasylol). (1989) (504)
Pronounced, Episodic Oxygen Desaturation in the Postoperative Period: Its Association with Ventilatory Pattern and Analgesic Regimen (1985) (428)
Effects of aprotinin on hemostatic mechanisms during cardiopulmonary bypass. (1987) (319)
Platelet transfusions during coronary artery bypass graft surgery are associated with serious adverse outcomes (2004) (313)
High-dose aprotinin therapy: a review of the first five years' experience. (1992) (282)
Reduced haemostatic factor transfusion using heparinase-modified thrombelastography during cardiopulmonary bypass. (2001) (230)
Increased production of peroxidation products associated with cardiac operations. Evidence for free radical generation. (1986) (180)
Retrograde tracing shows that CGRP-immunoreactive nerves of rat trachea and lung originate from vagal and dorsal root ganglia. (1987) (157)
Propofol infusion for sedation in the intensive care unit: preliminary report. (1987) (150)
Aprotinin therapy in cardiac operations: a report on use in 41 cardiac centers in the United Kingdom. (1993) (139)
The Society of Thoracic Surgeons practice guideline series: aspirin and other antiplatelet agents during operative coronary revascularization (executive summary). (2005) (138)
Innervation of the human cardiac conduction system. A quantitative immunohistochemical and histochemical study. (1994) (123)
Distribution, morphology, and neurochemistry of endocardial and epicardial nerve terminal arborizations in the human heart. (1995) (115)
The effect of surgery with cardiopulmonary bypass on alveolar-capillary barrier function in human beings. (1985) (111)
The inflammatory response and extracorporeal circulation. (1997) (99)
The physiology of leaky lungs. (1982) (97)
Enflurane anaesthesia causes graded changes in the brainstem and early cortical auditory evoked response in man. (1983) (97)
Propofol for long‐term sedation in the intensive care unit * A comparison with papaveretum and midazolam (1990) (93)
Thrombin generation and its inhibition: a review of the scientific basis and mechanism of action of anticoagulant therapies. (2002) (93)
Aprotinin versus lysine analogues: the debate continues. (1998) (84)
The serine antiprotease aprotinin (Trasylol): a novel approach to reducing postoperative bleeding. (1990) (77)
A comparison of two systems for assessing cerebral venous oxyhaemoglobin saturation during cardiopulmonary bypass in humans (1993) (76)
Preventing the inflammatory response to open-heart surgery: the role of aprotinin and other protease inhibitors. (1996) (76)
Comparison of lung vascular and epithelial permeability indices in the adult respiratory distress syndrome. (2015) (75)
Increased pulmonary transvascular protein flux after canine cardiopulmonary bypass. Association with lung neutrophil sequestration and tissue peroxidation. (1986) (70)
Changes in alveolar-capillary barrier function in animals and humans. (1983) (70)
Pro: lung transplantation should be routinely performed with cardiopulmonary bypass. (2000) (68)
Pharmacological approaches to reducing allogeneic blood exposure (2003) (67)
Serum methionine and hepatic enzyme activity in anaesthetists exposed to nitrous oxide. (1982) (63)
HISTAMINE INCREASES LUNG PERMEABILITY BY AN H2-RECEPTOR MECHANISM (1984) (62)
ADULT RESPIRATORY DISTRESS SYNDROME AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION: EVIDENCE FOR A NEUTROPHIL-INDEPENDENT MECHANISM (1985) (60)
Intravenous nitrate vasodilators and exhaled nitric oxide (1997) (59)
Blood‐sparing Drugs: Aprotinin, Tranexamic Acid, and &epsis;-Aminocaproic Acid (1994) (58)
Pulmonary epithelial permeability is immediately increased after embolisation with oleic acid but not with neutral fat. (1982) (57)
Rate of inactivation of human and rodent hepatic methionine synthase by nitrous oxide. (1988) (57)
EFFECT OF APROTININ ON NEED FOR BLOOD TRANSFUSION IN PATIENTS WITH SEPTIC ENDOCARDITIS HAVING OPEN-HEART SURGERY (1988) (55)
Acute ventilatory changes during i.v. induction of anaesthesia with thiopentone or propofol in man. Studies using inductance plethysmography. (1987) (54)
Coronary revascularization: a procedure in transition from on-pump to off-pump? The role of glucose-insulin-potassium revisited in a randomized, placebo-controlled study. (2002) (53)
Effect of temperature and cardiopulmonary bypass on the pharmacokinetics of remifentanil. (1997) (47)
Human endocardial innervation and its relationship to the endothelium: an immunohistochemical, histochemical, and quantitative study. (1994) (43)
The current place of aprotinin in the management of bleeding (2015) (43)
Is there a bleeding problem with platelet-active drugs? (2002) (43)
Full-Dose Aprotinin Use in Coronary Artery Bypass Graft Surgery: An Analysis of Perioperative Pharmacotherapy and Patient Outcomes (2006) (39)
Anaesthesia: the patient's point of view (2003) (38)
Aprotinin in aspirin-pretreated patients (1990) (36)
The effect of nicotine on pulmonary epithelial permeability in man. (1984) (36)
Effect of raised thoracic pressure and volume on 99mTc-DTPA clearance in humans. (1986) (36)
Systemic inflammatory responses to surgery with cardiopulmonary bypass (1996) (35)
Blood cell activation. (1990) (33)
Serine protease inhibition prevents both cellular and humoral responses to cardiopulmonary bypass. (1996) (32)
Acute lung injury during cardiopulmonary bypass, the role of neutrophil sequestration and lipid peroxidation. (1985) (32)
Aprotinin; friend or foe? A review of recent medical literature. (2007) (32)
Carboxyhaemoglobin and pulmonary epithelial permeability in man. (1983) (30)
A comparison of 99mTc-DTPA and 113mIn-DTPA aerosol clearances in humans. Effects of smoking, hyperinflation, and in vitro oxidation. (1987) (30)
Intraoperative coronary thrombosis: can aprotinin be incriminated? (1994) (29)
Remifentanil (2001) (29)
Case 1-2005: cardiac surgery in congenital afibrinogenemia with thrombo-occlusive disease. (2005) (28)
Inpatient experience with remifentanil. (1999) (27)
Patient selection and anesthetic management for early extubation and hospital discharge: CABG. (1998) (26)
Is Perioperative Plasma Aprotinin Concentration More Predictable and Constant After a Weight-Related Dose Regimen? (2001) (24)
Potential therapeutic applications of fructose-1,6-diphosphate. (1998) (23)
Basal and nitroglycerin-induced exhaled nitric oxide before and after cardiac surgery with cardiopulmonary bypass. (2003) (22)
Cardiopulmonary effects of 7.2% saline solution compared with gelatin infusion in the early postoperative period after coronary artery bypass grafting. (1998) (22)
Blood Use in Cardiac Surgery (1991) (22)
Cigarette smoke induced changes in rat pulmonary clearance of 99mTcDTPA. A comparison of particulate and gas phases. (1985) (20)
Efficacy and safety of remifentanil in coronary artery bypass graft surgery: a randomized, double-blind dose comparison study. (2003) (20)
Reduced blood loss following open heart surgery with aprotinin (Trasylol) is associated with an increase in intraoperative activated clotting time (ACT). (1989) (20)
APROTININ (TRASYLOL) REDUCES BLEEDING AFTER OPEN HEART SURGERY IN PATIENTS TAKING ASPIRIN AND THOSE WITH RENAL FAILURE (1989) (18)
True anaphylaxis to suxamethonium chloride. A case report. (1978) (18)
Safety aspects of aprotinin therapy in cardiac surgery patients (2006) (18)
EDITORIAL II Aprotinin therapy (1994) (18)
Aprotinin in open-heart surgery: background and results in patients having aortocoronary bypass grafts (1990) (18)
Effect of subanaesthetic concentrations of nitrous oxide on the regulation of ventilation in man. (1983) (18)
Epithelial and endothelial flux after bypass in dogs: effect of positive end-expiratory pressure. (1987) (18)
Myocardial Protection Using Fructose-1,6-Diphosphate During Coronary Artery Bypass Graft Surgery: A Randomized, Placebo-Controlled Clinical Trial (2004) (17)
Aprotinin therapy in heart and heart-lung transplantation. (1993) (17)
Comparison of respiratory characteristics during enflurane and halothane anaesthesia. (1981) (17)
Suxamethonium‐related hyperkalaemic cardiac arrest in intensive care (1995) (17)
Aprotinin Does Not Inhibit the Release of PGI2 or vWF from Cultured Human Endothelial Cells (1992) (16)
A case for aprotinin in patients having deep hypothermic circulatory arrest. (1997) (16)
Use of aprotinin therapy in a patient with factor V Leiden. (1997) (16)
Free radicals (1988) (16)
Changes in permeability of the alveolar-capillary barrier in firefighters. (1985) (16)
Aprotinin inhibits platelet adhesion to endothelial cells (1992) (16)
Double Fluorescent-amplification Refractory Mutation Detection (dF-ARMS) of the Factor V Leiden and Prothrombin Mutations (1999) (15)
Remifentanil in cardiac surgery. (1995) (15)
Exhaled nitric oxide as a marker of lung injury in coronary artery bypass surgery. (2003) (15)
Evaluating the role of serine protease inhibition in the management of tumor micrometastases. (2003) (15)
Cardiothoracic and vascular anesthesia. (1998) (14)
Effect of aprotinin on vascular reactivity of coronary bypass grafts. (1997) (14)
Aprotinin and perioperative complications in cardiac surgery. (2007) (14)
Early extubation after open-heart surgery with total intravenous anaesthetic technique (1995) (14)
Semi-autogenous grinding (SAG) mill liner design and development (2007) (14)
The unwanted response to cardiac surgery: time for a reappraisal? (2003) (14)
Does the combination of aprotinin and angiotensin-converting enzyme inhibitor cause renal failure after cardiac surgery? (2006) (14)
Coagulation in cardiac surgery. (1996) (14)
The effect of human antiendotoxin monoclonal antibodies on endotoxin-induced lung injury in the rat. (1987) (13)
Aprotinin decreases the need for post-operative blood transfusions in patients having open heart surgery. (1988) (13)
Surgery with cardiopulmonary bypass and pulmonary inflammatory responses (1996) (13)
A special article following the relicence of aprotinin injection in Europe. (2017) (12)
REDUCED HEMOSTATIC FACTOR TRANSFUSION USING HEPARINASE-MODIFIED THROMBELASTOGRAPHY (TEG) DURING CARDIOPULMONARY BYPASS (CPB) (1998) (12)
A simple separator to generate half micron aqueous particles for lung imaging. (1984) (12)
Failure of aerosolised 99mTc DTPA clearance to predict outcome in patients with adult respiratory distress syndrome. (1987) (11)
Aprotinin prevents bleeding and has effects on platelets and fibrinolysis. (1991) (11)
Non-Invasive Respiratory Monitoring (1987) (11)
PERIOPERATIVE BLEEDING Drugs for surgical blood loss (1993) (11)
Rate of Inactivation of Human and Rodent Hepatic Methionine Synthase by Nitrous Oxide (1988) (11)
Tranexamic acid in cardiac surgery: is there a cause for concern? (2010) (11)
Nitric oxide as mediator, marker and modulator of microvascular damage in ARDS. (2001) (11)
Preservation and protection of myocardial function. (2000) (10)
Long-term outcome of patients with perioperative myocardial infarction as diagnosed by troponin I after routine surgical coronary artery revascularization. (2006) (10)
Aprotinin in patients having coronary artery bypass graft surgery. (1995) (9)
Aprotinin and renal dysfunction. (2008) (9)
Aprotinin therapy. (1994) (9)
Hemostatic Drugs in Trauma and Orthopedic Practice (2001) (9)
Positive end-expiratory pressure increases pulmonary clearance of inhaled 99mTc-DTPA in nonsmokers but not in healthy smokers. (1987) (9)
Heat Transfer in the Flow of Solids in Gas Suspensions through a Packed Bed (1971) (9)
Determination of plasma aprotinin levels by functional and immunologic assays (2001) (9)
The comparison and validity of troponin I assay systems in diagnosing myocardial ischemic injury after surgical coronary revascularization. (2005) (8)
Microprocessor-controlled hemodynamics: a step towards improved efficiency and safety. (1989) (8)
Exhaled nitric oxide as a marker of lung injury in coronary artery bypass surgery. Authors' reply (2003) (8)
Improved performance with single dose phosphodiesterase inhibitor? (1998) (7)
Inhalational agents for pulmonary hypertension (1993) (7)
Interventions to reduce cerebral injury during cardiac surgery - the effect of physical and pharmacological agents (1989) (7)
Bypass and LPS induced pro-inflammatory activity in the plasma of patients undergoing CABG surgery (2002) (7)
Infused salbutamol accentuates acid-induced lung injury in the rat. (1986) (7)
Exhaled nitric oxide and pulmonary response to iloprost in systemic sclerosis (1998) (6)
Abnormality of an index of alveolar-capillary barrier permeability associated with respiratory tract infection in the rat (1983) (6)
Correlation between pulmonary gas exchange and basal and nitroglycerin (GTN)-induced exhaled nitric oxide (eNO) in patients undergoing cardiac surgery. (2005) (6)
Heart failure. (2004) (6)
Pro: aprotinin should be used in patients undergoing hypothermic circulatory arrest. (2001) (5)
ONCOLOGY Molecular basis for hormone-related cancer (1993) (5)
Aprotinin; an economy of truth? (2008) (5)
Some short-term effects of changing to lower yield cigarettes. (1985) (5)
Prevention of body temperature reduction (afterdrop) following hypothermic perfusion (1988) (5)
Protect the heart in the intensive care unit–but how? (2002) (4)
Aprotinin and renal dysfunction (2008) (4)
Lung injury following cardiopulmonary bypass; the potential role of oxidant-free radicals. (1986) (4)
Clinical Effectiveness of Aprotinin in Heart Surgery (1991) (4)
Activated clotting times are shortened by tranexamic acid (1998) (4)
Dynamics of nitroglycerin-induced exhaled nitric oxide after lung transplantation: evidence of pulmonary microvascular injury? (2007) (4)
The non‐steroidal anti‐inflammatory agent, indoprofen, does not protect against hydrochloric acid induced lung injury in the rat (1986) (4)
ACUTE/ADULT/ANIMAL RESPIRATORY DISTRESS SYNDROME A Sideways look at ARDS (1986) (4)
Thoughts on the Mechanism of Action of Aprotinin (2005) (3)
Neutrophil malondialdehyde content as an indicator of activation during cardiopulmonary bypass. (1986) (3)
Free radicals and cardiac arrhythmias following coronary surgery: actors of the drama or bystanders of the spectacle? (2003) (3)
SAG mill pulp-lifter design, discharge and backflow (2006) (3)
Techniques in Extracorporeal Circulation, 4th Edn. P. H. Kay and C. M. Munsch (editors). Published by Arnold, London. Pp. 354; indexed; illustrated. Price £110.00. ISBN 0-340-80723-7. (2004) (3)
Effects of fructose-1,6-diphosphate on endo- and myocardial purine metabolism during coronary artery bypass grafting surgery. (2007) (3)
Changes in body temperature following cardiopulmonary bypass procedures; the effects of active rewarming. (1986) (3)
Blood‐sparing Drugs: Aprotinin, Tranexamic Acid, and ε-Aminocaproic Acid (1995) (3)
A Comparison of Particulate and Gas Phases1,2 (1985) (3)
Exhaled Nitric Oxide in Patients Undergoing C Ardiothoracic Surgery: a New Diagnostic Tool? (1998) (2)
Do Preoperative Platelet Active Medication and Anticoagulants Increase Need for Transfusion?: [2002][A-187] (2002) (2)
Myocardial protection for cardiac surgery: classical views and new trends. (1999) (2)
Use and safety of aprotinin in routine clinical practice (2022) (2)
Anesthesia for the patient with a transplanted organ (1995) (2)
[Changes of exhaled nitrogen-monoxide concentration in acute ischemia-reperfusion injury of the lung]. (2002) (2)
Use of Intra-Operative High Dose Aprotinin May Be Associated with Improved Longer Term Outcome Following Esophagectomy for Cancer: [2002][A-1187] (2002) (2)
Pulmonary surgery and lung transplantation (1991) (1)
Pathways to complement activation during cardiopulmonary bypass (1985) (1)
Chapter 37 – Anticoagulant and Antiplatelet Therapy (2013) (1)
Anticoagulant and Antiplatelet Therapy (2019) (1)
Cigarette Smoke Induced Changes in Rat Pulmonary Clearance of 99mTcDTPA (2015) (1)
The effects of diaspirin cross-linked hemoglobin on the tone of human saphenous vein. (2001) (1)
Technical Note: Review of recent experience with largeangle, wide-spaced shell lifter-liners (2004) (1)
Antithrombotic and antiplatelet therapy (2015) (1)
Increased Lung Epithelial Permeability to Histamine is Mediated by H2 Receptors (1984) (1)
Drugs for surgical blood loss. (1993) (1)
Antifibrinolytic therapy during cardiac surgery (1996) (1)
Chlorinated Dioxins and Furans from Combustion Sources: A Review (1993) (1)
Coronary revascularization in transition from on-pump to off-pump: the effect of the off-pump coronary artery bypass on medium-term outcome. (2007) (1)
The Effect of Peep on Both Epithelial and Endothelial Permeability in Normal Humans (1985) (1)
DIAGNOSTIC ASPECTS OF EXHALED NITRIC OXIDE IN CARDIOTHORACIC ANAESTHESIA (2005) (1)
Brown, The Society of Cardiovascular Anesthesiologists Special Task Force on Blood (2008) (1)
Blood conservation in cardiac surgery (2000) (1)
COMPARISON OF PLASMA APROTININ CONCENTRATIONS USING WEIGHT RELATED AND FIXED DOSE REGIMEN (1998) (1)
A826 EFFECTS OF THORACIC EPIDURAL EPIDURAL ANESTHESIA ON PERIOPERATIVE OUTCOME IN CORONARY ARTERY BYPASS GRAFT (CABG) SURGERY (1997) (1)
Role of education and point of care analysis with thromboelastography to reduce transfusions after adult cardiac surgery: A-853 (2004) (0)
Room 302, 10/16/2000 2: 00 PM - 3: 30 PM (PD) Is ICU and Hospital Recovery after Off-Bypass (OPCAB) Superior to On-Bypass (CB) Revascularization? A-243 (2000) (0)
[Effect of fructose-1,6-diphosphate on myocardial purin and pyrimidin metabolism during coronary artery bypass grafting surgery]. (2000) (0)
Massive Blood Replacement (1999) (0)
Desmopressin and bleeding (1989) (0)
Aprotinin and perioperative complications in cardiac surgery: 4AP5-5 (2007) (0)
The Effects of Diaspirin Cross-Linked Hemoglobin on the Tone of Human Saphenous Vein (2001) (0)
Major surgery in von Willebrand's disease. (1989) (0)
True Anaphylaxis to Suxamethonium Chloride: A Case Report (1979) (0)
Changes inpermeability ofthealveolar-capilla ry barrier infirefighters (1985) (0)
Perioperative Blood Transfusion (2002) (0)
Allogeneic Platelet Transfusion: Risks and Alternatives (2002) (0)
ynamics of Nitroglycerin-induced Exhaled Nitric Oxide fter Lung Transplantation : Evidence of Pulmonary icrovascular Injury ? (2007) (0)
Mechanisms of bypass induced desensitisation of whole blood activation by endotoxin (LPS) (2002) (0)
A503 PROPOFOL DOES NOT ENHANCE THE RELEASE OF NITRIC OXIDE FROM HUMAN SAPHENOUS VEIN (1997) (0)
Room D, 10/16/2000 9: 00 AM - 11: 00 AM (PS) Heparin Influences Human Vascular Tissue Responses Involving the cGMP Pathway A-600 (2000) (0)
Fructose-1,6-diphosphate (FDP) prevents myocardial adenine nucleotide degradation in cardiac surgery (1998) (0)
Lung Epithelial and Endothelial Permeability in Smokers, Non-Smokers and Patients with ARDS (1985) (0)
Hunterston 'B' advanced gas cooled reactor-development of electrical auxiliary system with station life (1994) (0)
A86 Myocardial Protection and Performance Preservation by Fructose-1,6-di Phosphate Following Cardiac Surgery (1997) (0)
Correlation between Indices of Lung Vascular Permeability and Oxidative Function after Cardiopulmonary Bypass in Dogs (1985) (0)
Blood Conservation Strategies in Cardiac Surgery (2020) (0)
Operational Experience with Curved Pulp Lifters in AG/SAG Mills (2000) (0)
Expert Opinion on Investigational Drugs (1998) (0)
A COMPARISON OF REMIFENTANIL AND FENTANYL BASED ANAESTHESIA ON INDICES OF STRESS RESPONSE DURING MYOCARDIAL REVASCULARIZATION (1998) (0)
Room B, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Hypercoagulability by Genetic Laboratory and Clinical Outcomes Yields Significant by Divergent Relationships A-182 (2000) (0)
Crystalloids and colloid hydroxyethyl starch solutions do not change GPIb or P-Selectin function of platelets (2004) (0)
The role of the formed elements of the blood in host defense. (1999) (0)
Propofol infusion for sedation in the intensive care unit: (1987) (0)
Room B, 10/17/2000 2: 00 PM - 4: 00 PM (PS) Aprotinin Use in Patients Taking Inhibitors of Angiotensin Converting Enzyme (ACEI) A-199 (2000) (0)
Monitoring in anesthesiology: Current standards and newer techniques. Preface (1993) (0)
Abnormality of an indexof alveolar-capillary barrierpermeability associatedwithrespiratory tractinfectionin the rat (1983) (0)
A454 THROMBELASTOGRAPHIC EVALUATION OF THE INTERACTION BETWEEN REOPRO [trademark symbol] (C7E3 FAB) AND HEMOSTATIC DRUGS (1997) (0)
Use of Spontaneously Expired Volume (SEV) in Mechanically Ventilated Patients (1986) (0)
Hemostatic Drugs in Prothrombotic or Hypercoagulable States (1997) (0)
armful Effects of Aspirin in the Perioperative etting oes Preoperative Aspirin Cause Increased ostoperative Blood Loss ? (2005) (0)
Cardiothoracic Anesthesia and Critical Care in the United Kingdom (UK) Part 1: Some Insights Into the History and Development. (2021) (0)
Pre Bone Marrow Transplant Radiation and Chemotherapy Does Not Increase Pulmonary DTPA Clearance (1987) (0)
Process-data Acquisition in Hydrometallurgy (1985) (0)
Changing Concepts of Blood Use in Cardiac Surgery (1991) (0)
Aprotinin Relicense and Use of Nonapproved Interventions. (2019) (0)
Room 302, 10/18/2000 2: 00 PM - 3: 30 PM (PD) TEG® R-time is Directly Related to Hiridin Concentration in Whole Blood Following Stimulation with the Snake Venom Ecarin A-411 (2000) (0)
Coronary endothelial protection by fructose-1,6-diphosphate (FDP) in a rat Langendorrf model (2000) (0)
EFFECTS OF APROTININ ON VASCULAR REACTIVITY OF CORONARY BYPASS GRAFTS. COMMENTARY (1997) (0)
Arsenic removal by solvent extraction from copper tankhouse electrolyte (1984) (0)
Acute/adult/animal respiratory distress syndrome. (1986) (0)
Major issues in critical care medicine (1985) (0)
Prostacyclin, Cardiopulmonary Bypass and the Alveolar Capillary Membrane (1987) (0)
Differences between knowledge of the principles of safe and effective blood transfusion practice between anaesthetists, surgeons and nurses in adult cardiac surgery units: A-345 (2004) (0)
Irish Thoracic Society (1995) (0)
Hypercoagulable States (1997) (0)
Developments in cardiac transplantation (1995) (0)
Pharmacological Interventions to Prevent the Need for Blood and Blood Component Therapies:.: Protease Inhibitor or Lysine Analogue? (2001) (0)
EFFECT OF CROSS-LINKED HEMOGLOBIN ON HUMAN SAPHENOUS VEIN (1998) (0)
FRUCTOSE-1, 6-DIPHOSPHATE (FDP) ENHANCES HUMAN VASCULAR cGMP PRODUCTION (1998) (0)
New drug in anesthesia (1995) (0)

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What Schools Are Affiliated With D. E. Royston?

D. E. Royston is affiliated with the following schools:

Royal Postgraduate Medical School