David Norman Van Goeddel

David Norman Van Goeddel's AcademicInfluence.com Rankings

Biology

#5509

World Rank

#8008

Historical Rank

Molecular Biology

#496

World Rank

#507

Historical Rank

Biochemistry

#661

World Rank

#759

Historical Rank

biology Degrees

Download Badge

Biology

David Norman Van Goeddel's Degrees

PhD Biochemistry University of California, San Francisco
Bachelors Chemistry University of California, Santa Cruz

Why Is David Norman Van Goeddel Influential?

(Suggest an Edit or Addition)

(See a Problem?)

David Norman Van Goeddel's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. (1998) (2872)
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death (1996) (2107)
TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways (1996) (2035)
TNF-R1 Signaling: A Beautiful Pathway (2002) (1877)
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation (1995) (1870)
Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells (1985) (1667)
Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES (1990) (1458)
TRAF6 is a signal transducer for interleukin-1 (1996) (1381)
A novel domain within the 55 kd TNF receptor signals cell death (1993) (1370)
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand (1994) (1328)
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins (1995) (1292)
IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK (1997) (1181)
Identification and Characterization of an IκB Kinase (1997) (1162)
Two TNF receptors. (1992) (1109)
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor (1994) (1095)
Identification of Heregulin, a Specific Activator of p185erbB2 (1992) (982)
A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor (1989) (977)
Molecular cloning and expression of a receptor for human tumor necrosis factor (1990) (955)
Synthesis of Messenger RNAs for Transforming Growth Factors α and β and the Epidermal Growth Factor Receptor by Human Tumors (1987) (916)
Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue (1983) (898)
Human tumor necrosis factor. Production, purification, and characterization. (1985) (877)
The two different receptors for tumor necrosis factor mediate distinct cellular responses. (1991) (871)
Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB (1991) (849)
Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor (1989) (819)
The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. (1995) (810)
Human transforming growth factor-α: Precursor structure and expression in E. coli (1984) (763)
Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP). (1991) (725)
Tumour necrosis factors α and β inhibit virus replication and synergize with interferons (1986) (670)
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice (1994) (633)
Rational design of potent antagonists to the human growth hormone receptor. (1992) (623)
Expression of human immune interferon cDNA in E. coli and monkey cells (1982) (616)
Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. (1993) (609)
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. (1991) (598)
Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. (1997) (576)
Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases (1989) (563)
Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice (1999) (547)
Primary structure and biological activity of a novel human neurotrophic factor (1990) (541)
NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176 (1998) (531)
Biological properties of human c-Ha-ras1 genes mutated at codon 12 (1984) (531)
Human macrophage inflammatory protein alpha (MIP-1 alpha) and MIP-1 beta chemokines attract distinct populations of lymphocytes (1993) (503)
Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization. (1985) (497)
The murine transforming growth factor-beta precursor. (1986) (467)
Structure of the human immune interferon gene (1982) (452)
Human leukocyte interferon produced by E. coli is biologically active (1980) (435)
Molecular Biology of the Natriuretic Peptides and Their Receptors (1992) (431)
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. (1996) (429)
Effect of interleukin 2, interferon-gamma, and mitogens on the production of tumor necrosis factors alpha and beta. (1985) (428)
Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. (1999) (427)
The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation. (1996) (426)
Cloning and expression of murine immune interferon cDNA. (1983) (419)
Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice (2001) (409)
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90. (2002) (402)
A death-domain-containing receptor that mediates apoptosis (1996) (372)
Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor. (1985) (363)
Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor (1993) (359)
Expression in rat fibroblasts of a human transforming growth factor-α cDNA results in transformation (1986) (340)
Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction. (1989) (329)
Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor. (1993) (317)
NF-k B Antiapoptosis : Induction of TRAF 1 and TRAF 2 and c-IAP 1 and c-IAP 2 to Suppress Caspase-8 Activation (1998) (308)
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. (1997) (297)
Anatomy of TRAF2 (1996) (295)
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene (1983) (290)
Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin. (1991) (286)
Expression of a human gene for interferon in yeast (1981) (285)
The IκB Function of NF-κB2 p100 Controls Stimulated Osteoclastogenesis (2003) (258)
Membrane guanylate cyclase is a cell-surface receptor with homology to protein kinases (1988) (250)
Identification of human uromodulin as the Tamm-Horsfall urinary glycoprotein. (1987) (248)
Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1 beta. (1986) (243)
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice. (1999) (235)
I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. (1996) (224)
Molecular cloning of a retina-specific membrane guanylyl cyclase (1992) (207)
Tumor necrosis factors: gene structure and biological activities. (1986) (202)
Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides (1985) (202)
Identification and characterization of an IkappaB kinase. (1997) (200)
Posttranscriptional Downregulation of c-IAP2 by the Ubiquitin Protein Ligase c-IAP1 In Vivo (2005) (198)
Differential regional expression of three natriuretic peptide receptor genes within primate tissues (1991) (193)
Synthesis of human fibroblast interferon by E. coli. (1980) (192)
Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes (1987) (189)
Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. (2001) (184)
Human transforming growth factor-alpha: precursor structure and expression in E. coli. (1984) (173)
Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75 (1995) (173)
Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors. (1987) (172)
NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176. (1998) (171)
NF-κB Activation by Interleukin-1 (IL-1) Requires an IL-1 Receptor-associated Protein Kinase Activity (*) (1995) (169)
RANTES secretion by gene-modified tumor cells results in loss of tumorigenicity in vivo: role of immune cell subpopulations. (1996) (166)
Secretion of human interferons by yeast. (1983) (161)
Human immune interferon gene is located on chromosome 12 (1983) (148)
Rabies virus glycoprotein analogs: biosynthesis in Escherichia coli. (1983) (142)
Tumor necrosis factor-α pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury (1992) (134)
Natural killer-sensitive targets stimulate production of TNF-alpha but not TNF-beta (lymphotoxin) by highly purified human peripheral blood large granular lymphocytes. (1986) (132)
Antiviral activities of hybrids of two major human leukocyte interferons. (1981) (131)
Precursor structure, expression, and tissue distribution of human guanylin. (1992) (127)
Molecular cloning and expression of Pgp-1. The mouse homolog of the human H-CAM (Hermes) lymphocyte homing receptor. (1989) (118)
Tumor necrosis factor receptor signaling. A dominant negative mutation suppresses the activation of the 55-kDa tumor necrosis factor receptor. (1992) (108)
Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases (1992) (108)
Proper glycosylation and phosphorylation of the type A natriuretic peptide receptor are required for hormone-stimulated guanylyl cyclase activity. (1993) (107)
Leukocyte and fibroblast interferon genes are located on human chromosome 9. (1981) (104)
Interferon-gamma induces receptor dimerization in solution and on cells. (1993) (93)
DNA sequence of two closely linked human leukocyte interferon genes. (1981) (90)
Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis. (1994) (88)
Primary structure and biological activity of human brain-derived neurotrophic factor. (1991) (86)
Increased synthesis in E. coli of fibroblast and leukocyte interferons through alterations in ribosome binding sites. (1982) (83)
The amino acid sequence of murine p53 determined from a c-DNA clone. (1984) (81)
Human fibroblast interferon gene lacks introns. (1981) (81)
Identification and characterization of a novel tyrosine kinase from megakaryocytes. (1994) (80)
Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster. (1982) (80)
Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily. (1994) (70)
T6BP, a TRAF6-interacting protein involved in IL-1 signaling. (2000) (70)
Physical mapping and genomic structure of the human TNFR2 gene. (1996) (70)
Hormonal induction of low affinity receptor guanylyl cyclase. (1993) (68)
MIP-T3, a Novel Protein Linking Tumor Necrosis Factor Receptor-associated Factor 3 to the Microtubule Network* (2000) (68)
Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation. (1992) (66)
Characterization of a recombinant extracellular domain of the type 1 tumor necrosis factor receptor: evidence for tumor necrosis factor-alpha induced receptor aggregation. (1992) (66)
Heterologous expression and characterization of the human R-ras gene product (1987) (65)
Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptor. (1993) (65)
DNA sequence of a major human leukocyte interferon gene. (1981) (61)
The Structure and Bacterial Expression of Three Distinct Bovine Interferon-β Genes (1984) (59)
Nucleotide sequence of human preproinsulin complementary DNA. (1980) (58)
Interferon-gamma enhances induction of lymphotoxin in recombinant interleukin 2-stimulated peripheral blood mononuclear cells. (1985) (55)
Expression of the human interferon–γ cDNA in yeast (1983) (55)
Determination of the solution structure of the peptide hormone guanylin: observation of a novel form of topological stereoisomerism. (1994) (53)
Signal transduction by tumor necrosis factor: the Parker B. Francis Lectureship. (1999) (52)
NF-kappa B activation by tumor necrosis factor and interleukin-1. (1999) (52)
Uncoupling of cytokine mRNA expression and protein secretion during the induction phase of T cell anergy. (1992) (51)
The extracellular domain of the human interferon gamma receptor interacts with a species-specific signal transducer (1991) (46)
NF-κB-Inducing Kinase Regulates Selected Gene Expression in the Nod2 Signaling Pathway (2006) (45)
cDNA sequence of the human atrial natriuretic peptide clearance receptor. (1990) (44)
Bacterial synthesis of a novel human leukocyte interferon. (1981) (44)
Biochemical characterization of the extracellular domain of the 75-kilodalton tumor necrosis factor receptor. (1993) (43)
A single amino acid change in IFN-β1 abolishes its antiviral activity (1981) (43)
Chromosomal distribution of three members of the human natriuretic peptide receptor/guanylyl cyclase gene family. (1990) (40)
Characterization of the recombinant human receptor for Escherichia coli heat-stable enterotoxin. (1992) (40)
NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity. (1995) (39)
Human Interferon γ is encoded by a single class of mRNA (1982) (32)
Human differentiation-stimulating factor (leukemia inhibitory factor, human interleukin DA) gene maps distal to the Ewing sarcoma breakpoint on 22q. (1989) (29)
The membrane form of guanylate cyclase. (1988) (29)
Random PCR mutagenesis screening of secreted proteins by direct expression in mammalian cells. (1992) (26)
Chimeric proteins define variable and essential regions of Ha-ras-encoded protein. (1988) (26)
Human tumour necrosis factors: structure and receptor interactions. (1987) (21)
Carboxyterminal region of hybrid leukocyte interferons affects antiviral specificity. (1982) (21)
Obituary: Robert A. Swanson (1947–99) (2000) (20)
Enhanced synthesis of tumor necrosis factor-inducible proteins, plasminogen activator inhibitor-2, manganese superoxide dismutase, and protein 28/5.6, is selectively triggered by the 55-kDa tumor necrosis factor receptor in human melanoma cells. (1994) (17)
NF-kappa B-inducing kinase regulates selected gene expression in the Nod2 signaling pathway. (2006) (16)
Inhibitors of apoptosis (1997) (15)
Structure and chromosomal localization of the human lymphotoxin gene (1985) (14)
Expression of the human interferon-gamma cDNA in yeast. (1983) (13)
Human Immune Interferon (IFN-γ) Gene Sequence and Structure (1983) (12)
Processing and characterization of human proguanylin expressed in Escherichia coli. (1993) (12)
Human interferon gamma is encoded by a single class of mRNA. (1982) (12)
The interferon-gamma receptor extracellular domain. Non-identical requirements for ligand binding and signaling. (1994) (10)
Human immune interferon (IFN-gamma) gene sequence and structure. (1983) (7)
PLASMID-DIRECTED SYNTHESIS OF HUMAN IMMUNE INTERFERON IN E. COLI AND MONKEY CELLS (1982) (6)
Hydrophobicity of Human Interferons (1982) (6)
Endogenous and heterologous expression of transforming growth factor-alpha in mammalian cells. (1986) (5)
Molecular cloning and analysis of lymphokines (1987) (4)
Protective Roles of MnSOD, TNF-α, TNF-β and D-Factor in Radiation Injury (1993) (4)
THE HUMAN LEUKOCYTE INTERFERON GENE FAMILY: STRUCTURE AND EXPRESSION IN MAMMALIAN CELLS (1981) (2)
The effect of tumor necrosis factor (TNF) on antioxidant enzyme expression (1990) (2)
Tumor necrosis factor signaling mechanisms. (1996) (2)
Coordinately Expressed and Encode Functional Polypeptides (1)
Expression of Human Interferon-γ in Heterologous Systems Genentech, Inc. Contribution no. 134. (1983) (1)
Bacterial production of human leukocyte interferon. (1981) (1)
SYNTHESIS OF HUMAN INTERFERONS AND ANALOGS IN HETEROLOGOUS CELLS (1982) (1)
4742003 Human transforming growth factor (1989) (1)
Monoclonal Antibodies Specific for Murine p55 and p75 Tumor Necrosis Factor Receptors: Identification of a Novel In Vivo Role for p75 By Kathleen C. F. Sheehan, J. Keith Pinckard, Cora D. Arthur, (1995) (1)
ISOLATION AND CHARACTERIZATION OF HUMAN IMMUNE INTERFERON (IFN-γ) MESSENGER RNA (1982) (0)
Procedes et compositions de traitement de lesions (1991) (0)
Fremgangsaade for the preparation of polypeptides (1981) (0)
Dna encoding hybrid type human leukocyte interferon (1992) (0)
The Antiviral Effects of Tumor Necrosis Factors (1987) (0)
Human Tumors and the Epidermal Growth Factor Receptor by β and α Factors Synthesis of Messenger RNAs for Transforming Growth (2006) (0)
Procedures and preparations for the treatment of injuries (1991) (0)
Interferoner and the process Foer deras framstaellning (1981) (0)
Cancer therapy with lymphotoxin (1995) (0)
Process for the preparation of human tumor necrosis factor and the DNA encoding the (1985) (0)
Process for the preparation of necrosis factor (1994) (0)
Tumornecrosefaktorderivater, DNA coding therefor, replicable expression vectors containing the DNA, host cells transformed therewith and to a process for the preparation of tumornecrosefaktorderivaterne as well as compositions comprising tumornecrosefaktorderivaterne (1994) (0)
Compositions and methods for the synthesis of b-receptor for the natriuretic protein and methods of use (1990) (0)
Methods for the preparation of human immune interferon (gamma-interferon) and DNA fragments, cloning and recombinant expression vectors and recombinant microorganisms and cell cultures for use thereby (1982) (0)
Regulation of gene expression in oxidative stress (1993) (0)
ElResearch Advances Series Focus on Molecular Biology Molecular Biology of the Natriuretic Peptides and Their Receptors (2005) (0)
The Pathway of Exocytosis in Human Platelets (2017) (0)
Polypeptides having the amino acid sequence of a mature human leukocyte interferon without pre-sequence, their preparation and use (1981) (0)
Tumor necrosis factor, processes for its production, compositions containing the same, daf} r-encoding DNA and this DNA-use test driving. (1985) (0)
Heterologous Expression andCharacterization oftheHuman R-rasGeneProduct (1987) (0)
Secretion of Human Interferons by Yeast (2019) (0)
IKK-β-PROTEIN, NUCLEIC ACID AND METHOD (2003) (0)
Human fibroblast interferon and its preparation (1981) (0)
A process for preparing an antiviral polypeptide and to a double-stranded DNA comprising a sequence encoding (1981) (0)
A process for the production of TGF-beta, DNA and mRNA coding for TGF-beta, as well as replicable vectors comprising the DNA and host cells containing the vectors (1986) (0)
Molecular cloning and analysis of lymphokines. Volume 13 (1987) (0)
Human Preproinsulin: Primary Structure of the Messenger RNA (1980) (0)
Mature human leukocyte interferon; a bacterium that can produce such an interferon, and a process for preparing (1981) (0)
Conservation of the Kinaselike Regulatory Domain (0)
Mature human leukocyte interferons, to processes for their bacteriellen preparation, intermediates for this and compositions containing them. (1981) (0)
Foerfarande Foer framstaellning of humant immuninterferon, daervid anvaendbara agents, and dessas framstaellning. (1982) (0)
Animal interferons, procedures for their preparation, compositions containing them, encoding DNA sequences therefor and these sequences containing expression vectors and thereby transformed cells. (1983) (0)
Factors associated with the tumor necrosis factor receptor type 2 (TNF-R2). (1995) (0)
Novel animal interfers, process for their production and composition containing same (1983) (0)
Interferons and their production (1981) (0)
Human transforming growth factor and precursor or fragment thereof, cells, DNA, vectors and methods for their preparation, compositions and products containing them, and antibodies derived therefrom and diagnostic methods. (1985) (0)
The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-cB activation (2005) (0)
Differential expression of the class i and ii interferon alpha genes characterization by gene cloning and antibody neutralization (1985) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With David Norman Van Goeddel?

David Norman Van Goeddel is affiliated with the following schools:

Stanford University

David Norman Van Goeddel's Academic­Influence.com Rankings

David Norman Van Goeddel's Degrees

Why Is David Norman Van Goeddel Influential?

David Norman Van Goeddel's Published Works

Published Works

What Schools Are Affiliated With David Norman Van Goeddel?

David Norman Van Goeddel's AcademicInfluence.com Rankings