Dr. David Vázquez
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Chemistry Biology
Dr. David Vázquez's Degrees
- Masters Chemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is Dr. David Vázquez Influential?
(Suggest an Edit or Addition)Dr. David Vázquez's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inhibitors of Protein Biosynthesis (1979) (385)
- Inhibitors of protein synthesis (1974) (296)
- Inhibition of translation in eukaryotic systems by harringtonine. (1977) (243)
- Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains. (1975) (196)
- Structural modifications in the peptidoglycan of Escherichia coli associated with changes in the state of growth of the culture (1985) (164)
- Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. (1978) (163)
- Binding of chloramphenicol to ribosomes. The effect of a number of antibiotics. (1966) (145)
- Thionins: plant peptides that modify membrane permeability in cultured mammalian cells. (1981) (138)
- Substrate- and antibiotic-binding sites at the peptidyl-transferase centre of Escherichia coli ribosomes. Studies on the chloramphenicol. lincomycin and erythromycin sites. (1971) (131)
- Inhibitors of protein synthesis in eukarytic cells. Comparative effects of some amaryllidaceae alkaloids. (1976) (118)
- Dual interference of hygromycin B with ribosomal translocation and with aminoacyl-tRNA recognition. (1978) (114)
- Substrate and antibiotic binding sites at the peptidyl transferase centre of E. coli ribosomes (1970) (113)
- Inhibition of ribosomal translocation by aminoglycoside antibiotics. (1978) (112)
- Action of Sparsomycin on Ribosome-catalysed Peptidyl Transfer (1969) (103)
- Cooperative and antagonistic interactions of peptidyl-tRNA and antibiotics with bacterial ribosomes. (1977) (102)
- Inhibitors of protein synthesis by ribosomes of the 80-S type. (1971) (95)
- Effects of some inhibitors of protein synthesis on the binding of aminoacyl tRNA to ribosomal subunits. (1967) (89)
- The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomes. (1973) (86)
- Synthesis and mode(s) of action of a new series of imide derivatives of 3-nitro-1,8 naphthalic acid (2004) (85)
- Inhibition by siomycin and thiostrepton of both aminoacyl-tRNA and factor G binding to ribosomes. (1971) (84)
- Plant and fungal protein and glycoprotein toxins inhibiting eukaryote protein synthesis. (1985) (82)
- Substrate and antibiotic binding sites at the peptidyl transferase centre of E. coli ribosomes: Binding of UACCA‐Leu to 50 S subunits (1971) (78)
- Antibiotics affecting chloramphenicol uptake by bacteria. Their effect on amino acid incorporation in a cell-free system. (1966) (76)
- Effects of some proteins that inactivate the eukaryotic ribosome (1977) (76)
- (3H)anisomycin binding to eukaryotic ribosomes. (1974) (75)
- Effects of ricin on the ribosomal sites involved in the interaction of the elongation factors. (1975) (75)
- Simultaneous ribosomal resistance to trichodermin and anisomycin in Saccharomyces cerevisiae mutants. (1975) (74)
- The mode of action of the antitumor drug bouvardin, an inhibitor of protein synthesis in eukaryotic cells (1982) (69)
- Inhibition by elongation factor EF G of aminoacyl-tRNA binding to ribosomes. (1972) (66)
- Narciclasine: an antitumour alkaloid which blocks peptide bond formation by eukaryotic ribosomes (1975) (63)
- The Streptogramin Family of Antibiotics (1967) (59)
- Intercalative binding to DNA of antitumour drugs derived from 3-nitro- 1, 8-naphthalic acid (1979) (56)
- Protein Synthesis and Translation Inhibitors (1979) (54)
- Initiation of the polypeptide chain by reticulocyte cell-free systems. Survey of different inhibitors of translation. (1976) (51)
- Specific location of penicillin-binding proteins within the cell envelope of Escherichia coli (1986) (49)
- Binding of (acetyl-14C)trichodermin to the peptidyl transferase centre of eukaryotic ribosomes. (1974) (48)
- Inhibition by aminoacyl transfer ribonucleic acid of elongation factor G-dependent binding of guanosine nucleotide to ribosomes. (1973) (47)
- Differences in eukaryotic ribosomes detected by the selective action of an antibiotic. (1973) (46)
- Ribosomes, G-factor and siomycin. (1971) (45)
- Catalysis of peptidyl transfer by human tonsil ribosomes and effects of some antibiotics (1970) (45)
- Bruceantin, a novel inhibitor of peptide bond formation. (1978) (44)
- Peptidyl transferase center of rat-liver ribosome cores. (1977) (44)
- Competition between trichodermin and several other sesquiterpene antibiotics for binding to their receptor site(s) on eukaryotic ribosomes. (1976) (42)
- Inhibitors of polypeptide elongation on yeast polysomes. (1975) (42)
- Ribosome changes during translation. (1975) (40)
- Antibiotics that specifically block translation in virus-infected cells. (1980) (39)
- Location of resistance to the alkaloid narciclasine in the 60S ribosomal subunit (1975) (39)
- Polypeptide-chain elongation promoted by guanyl-5'-yl imidodiphosphate. (1976) (37)
- Ribosomal translocation promoted by guanylylimido diphosphate and guanylyl‐methylene diphosphonate (1975) (36)
- Interaction between a 3-nitrobenzothiazolo (3,2-a) quinolinium antitumour drug and deoxyribonucleic acid. (1983) (35)
- The stoichiometry of ribosomal translocation. (1973) (35)
- Quantitative binding of antibiotics to ribosomes from a yeast mutant altered on the peptidyl-transferase center. (1975) (34)
- Penicillin binding proteins: role in initiation of murein synthesis in Escherichia coli. (1985) (34)
- Protein toxins that catalytically inactivate ribosomes from eukaryotic microorganisms Studies on the mode of action of alpha sarcin, mitogillin and restrictocin: Response to alpha sarcin antibodies (1978) (33)
- Synergistic interaction of the streptogramins with the ribosome. (1977) (33)
- Location of some proteins involved in peptidoglycan synthesis and cell division in the inner and outer membranes of Escherichia coli (1985) (33)
- Survey of inhibitors in different steps of protein synthesis by mammalian ribosomes. (1972) (32)
- Activities of ribosomal cores deprived of proteins L7, L10, L11 and L12 (1974) (31)
- Binding of [3H]narciclasine to eukaryotic ribosomes. A study on a structure-activity relationship. (1978) (31)
- Reconstitution of the 50S ribosome subunit. Role of proteins L 7 and L 12 in the GTPase activities. Site of action of thiostrepton (1972) (29)
- Structure-activity relationships of sparsomycin and its analogues. Inhibition of peptide bond formation in cell-free systems and of L1210 and bacterial cell growth. (1987) (29)
- Functional interaction of neomycin B and related antibiotics with 30S and 50S ribosomal subunits. (1979) (29)
- Elongation factor T-dependent hydrolysis of guanosine triphosphate resistant to thiostrepton. (1972) (28)
- Activities of nucleoprotein particles derived from rat liver ribosome. (1976) (28)
- Streptomycin‐ and viomycin‐induced conformational changes of ribosomes detected by iodination (1978) (28)
- Chemical and spectroscopic evidence on the homology of three antitumor proteins: α-sarcin, mitogillin, and restrictocin (1983) (27)
- The elongation steps in protein synthesis by eukaryotic ribosomes: effects of antibiotics. (1974) (27)
- [51] Ribosomal peptidyltransferase: Binding of inhibitors (1971) (25)
- Alteration of ribosomal proteins and functions by 2-methoxy-5-nitrotropone. (1974) (25)
- [G‐3H] Gougerotin Binding to Ribosomes (1974) (24)
- Anisomycin and Related Antibiotics (1979) (24)
- Specific inhibition of translocation by tubulosine in eukaryotic polysomes. (1976) (24)
- Inhibition, by selected antibiotics, of protein synthesis in cells growing in tissue cultures. (1978) (24)
- Site of action of ricin on the ribosome. (1976) (24)
- Activities of protein-deficient particles derived from 50-S ribosomal subunits by NH4Cl/ethanol treatment. (1976) (23)
- Studies on the mode of action of the streptogramin antibiotics. (1966) (23)
- Molecular bases for the action and selectivity of nucleoside antibiotics (1984) (23)
- Thermochemistry of the interaction between peptides and vancomycin or ristocetin. (1986) (22)
- Inhibitors of protein synthesis at the ribosome level. Studies on their site of action. (1967) (22)
- Comparative studies on cytoplasmic ribosomes from algae. (1968) (22)
- Inhibitors as Tools in Elucidating Ribosomal Function (1969) (20)
- Interaction of Ac‐Phe‐tRNA with e. coli ribosomal subunits. 1. Sparsomycin‐induced formation of a complex containing 50 S and 30 S subunits but not mRNA (1970) (20)
- Ribosomal sites involved in binding of aminoacyl‐tRNA and EF 2. mode of action of fusidic acid (1973) (19)
- The effects of the rifamycin antibiotics on algae (1970) (19)
- [46] Preparation of active 60 S and 40 S subunits from yeast ribosomes (1971) (19)
- Stoichiometry of polypeptide chain elongation. (1976) (19)
- Interaction of nocardicin A with the penicillin-binding proteins of Escherichia coli in intact cells and in purified cell envelopes. (1982) (19)
- Molecular mechanisms of antibiotic action on protein biosynthesis and membranes : Proceedings of a symposium held at the University of Granada (Spain) June 1st-4th, 1971 (1972) (18)
- Modification of penicillin-binding proteins of Escherichia coli associated with changes in the state of growth of the cells (1982) (18)
- Carbenicillin resistance of Pseudomonas aeruginosa (1982) (17)
- Compounds affecting membranes that inhibit protein synthesis in yeast (1979) (17)
- Binding to ribosomes and mode of action of chloramphenicol analogues. (1974) (17)
- The involvement of protein L16 on ribosomal peptidyl transferase activity. (1977) (16)
- Failure of fusidic acid and siomycin to block ribosomes in the pretranslocated state. (1972) (15)
- The involvement of sulphydryl groups in the peptidyl transferase centre of eukaryotic ribosomes. (1975) (15)
- Specific release of ribosomal proteins by nucleic acid-intercalating agents. (1976) (15)
- The interaction of fusidic acid with peptidyl-transfer-ribonucleic-acid - ribosome complexes. (1975) (15)
- Induction of cell lysis in Escherichia coli: cooperative effect of nocardicin A and mecillinam (1982) (14)
- Reversible modification of Escherichia coli ribosomes with 2,3-dimethylmaleic anhydride. A new method to obtain protein-deficient ribosomal particles. (1979) (14)
- 1,3-dioxolane formation with a montmorillonite-type clay catalyst (1992) (14)
- Inhibition of translation in bacterial and eukaryotic systems by the antibiotic anthelmycin (hikizimycin). (1979) (14)
- Proteins associated with rRNA in the Escherichia coli ribosome. (1978) (13)
- Interaction of β‐lactam antibiotics with penicillin‐binding proteins from Pseudomonas aeruginosa (1982) (13)
- Reconstitution of the 50 S ribosome subunit. Localization of activities related to the peptidyl transferase centre (1971) (13)
- Reconstitution of the 50 S ribosome subunit. Localization of G‐dependent GTPase activity (1971) (12)
- Analysis of the different molecular forms of penicillin-binding protein 1B in Escherichia coli ponB mutants lysogenized with specialized transducing lambda (ponB+) bacteriophages. (1984) (12)
- Stimulation of polypeptide polymerization in Escherichia coli ribosomes by modification of ribosomal sulfhydryl groups with N-bromosuccinimide. (1978) (11)
- Dissociation of guanosine nucleotide-elongation factor G-ribosome complexes. (1979) (11)
- The enhancement of polypeptide synthesis in mammalian systems by methylxanthines (1974) (11)
- Viral Translation Inhibitors (1983) (11)
- Structure and Function of Rat‐Liver Ribosomes (1976) (11)
- Conformational changes in ribosomes induced by alcohols (1979) (10)
- Antibiotics and compounds affecting translation by eukaryotic ribosomes. Specific enhancement of aminoacyl-tRNA binding by methylxanthines (1976) (10)
- Structure of the yeast ribosomes. Proteins associated with the rRNA. (1978) (9)
- Effect of a relA mutation on the growth-dependent modification of penicillin-binding protein 3 in Escherichia coli (1983) (9)
- Interaction of arginine with the ribosomal peptidyl transferase centre. (1979) (9)
- Kinetic studies of peptide bond formation. Effect of chloramphenicol (1973) (9)
- TWENTY FIVE YEARS OF RESEARCH ON INHIBITORS OF PROTEIN SYNTHESIS: PROSPECTS FOR FUTURE DEVELOPMENTS IN THE SUBJECT (1976) (9)
- Initiation of translation with native 40-S ribosomal subunits. (1978) (9)
- Interaction of beta-lactam antibiotics with penicillin-binding proteins from Bacillus megaterium. (1982) (8)
- Labelling and cross-linking of Escherichia coli penicillin-binding proteins with bis-beta-lactam antibiotics. (1984) (8)
- Preparation of pure (3H)anisomycin by tritium exchange labeling. (1973) (8)
- A method for the preparation of bacterial 50-S ribosome subunits. (1965) (8)
- Action of Inhibitors of Protein Biosynthesis (1982) (8)
- DISTRIBUTION OF PENICILLIN-BINDING PROTEINS WITHIN THE CELL ENVELOPE OF Escherichia coli (1983) (8)
- Inhibitory effects of 'cap' analogues on globin mRNA and encephalomyocarditis RNA translation in a reticulocyte cell-free system. (1980) (7)
- Binding of 125I-labeled beta-lactam antibiotics to the penicillin binding proteins of Escherichia coli. (1984) (7)
- Detection of guanosine-nucleotide.elongation-factor-G complexes produced during the decay of guanosine-nucleotide.elongation-factor-G.Ribosome complexes. (1977) (7)
- The Molecular Biology of a Bacterial Endosymbiont1 (1992) (7)
- Structural modification of Escherichia coli peptidoglycan induced by bicyclomycin. (1986) (6)
- Peptidyl transferase of bacterial ribosome: resistance to proteinase K. (1979) (6)
- Inhibitors of mammalian protein synthesis. (1974) (6)
- Implication of arginyl residues in mRNA binding to ribosomes. (1980) (6)
- Functional roles of 50-S ribosomal proteins. (1977) (5)
- The formation of guanosine-nucleotide - elongation-factor-G - ribosome complexes on free 70-S ribosomes, 50-S subunits, and polysomes. A comparative study. (1977) (5)
- GROWTH DEPENDENT MODIFICATIONS OF THE PENICILLIN BINDING PROTEINS OF Escherichia coli : INFORMATION SUPPORTING THE GENERALITY OF THE PROCESS AND THE MULTIPLICITY OF MECHANISMS (1983) (5)
- Application of a charge/size two‐dimensional gel electrophoresis system to the analysis of the penicillin‐binding proteins of Escherichia coli (1984) (5)
- Interaction of Ac‐Phe‐tRNA with E. coli ribosomal subunits. 2. Resistance of the sparsomycin‐induced complex to hydroxylamine action (1970) (5)
- Polysomal ribosomes complexed with elongation factor G can engage in the peptidyl transfer reaction (1976) (4)
- Antibiotic Action on the Ribosomal Peptidyl Transferase Centre (1975) (4)
- Binding of puromycin to E. coli ribosomes. Effects of puromycin analogues and peptide bond formation inhibitors (1973) (4)
- Novel Inhibitors of Translation in Eukaryotic Systems (1983) (4)
- Macrolide antibiotics — Spiramycin, Carbomycin, Angolamycin, Methymycin and Lancamycin (1967) (4)
- The mode of action of zaluzanin C, an inhibitor of translation in eukaryotes. (1984) (4)
- Partial reconstitution of active ribosomes and 50S subunits. (1975) (4)
- Effects on ribosomal activity and structure of modification with succinic, maleic and acetic anhydrides (1978) (3)
- Labelling of penicillin‐binding proteins from Escherichia coli with photoreactive derivatives of β‐lactam antibiotics (1983) (3)
- The mode of action of griseoviridin at the ribosome level. (1975) (3)
- Synthesis and biological activity of [14a-3H]cryptopleurine. (1980) (3)
- The mechanisms of selectivity and action of protein synthesis inhibitors (1973) (3)
- Affinity labelling of yeast ribosomal peptidyl transferase (1978) (3)
- An unusual linkage between polysaccharides and some major proteins from the outer membrane of Escherichia coli (1985) (2)
- Penicillin-binding proteins and peptidoglycan peptide-interacting proteins. (1984) (2)
- CALORIMETRIC STUDIES ON THE BINDING OF VANCOMYCIN - LIKE ANTIBIOTICS TO PEPTIDOGLYCAN (1983) (2)
- Selectivity and Specificity Reconsidered (1979) (2)
- Effect of a A mutation on the growth-dependent modification of penicillin-binding protein 3 in (1983) (2)
- Binding of aminoacyl-tRNA to rat liver ribosomal proteins (1976) (2)
- Preparation of (3H)anisomycin and (3H)gougerotin: binding to eukaryotic ribosomes. (1974) (2)
- Final steps of the maturation of Omp F, a major protein from the outer membrane of Escherichia coli (1985) (1)
- Antibiotic action in protein synthesis. (1973) (1)
- Modification of penicillin-binding proteins of associated with changes in the state of growth of the cells (1982) (1)
- Nucleoside Antibiotics. Mode of Action (1981) (1)
- Structure and function of rat-liver ribosomes. Modification by 2-methoxy-5-nitrotropone treatment. (1976) (1)
- Effect of Protein Synthesis Inhibition on the Induction of Cell Lysis in Escherichia coli by Mecillinam plus Nocardicin A (1982) (1)
- Structure-activity relationships between cryptopleurine and related compounds acting on yeast cell-free systems (1980) (1)
- Control of ribosome synthesis. An approach to the integrated picture of the bacterial control of ribosome synthesis: edited by Niels Chr. Kjeldgaard and Ole Maaløe, published by Munksgaard, Copenhagen, Academic Press, New York, 1976. Kr220-(approx.$36.-) (466 pages) (1976) (1)
- A mutation of Saccharomyces cerevisiae leading to resistance to some inhibitors of peptide bond formation (2004) (1)
- Control by Peptidyl-tRNA of Elongation Factor G Interaction with the Ribosome (1974) (0)
- Cell Evolution and the Selective Action of Translation Inhibitors (1984) (0)
- SOME ASPECTS OF THE MECHANISM OF EXPRESSION OF PBP 3 IN E.coli II. Differential Behaviour of Transducing Phages Complementing the pbpB Thermosensitive Mutation2158 (1983) (0)
- Protein and Glycoprotein Toxins That Inactivate the Eukaryotic Ribosome (1979) (0)
- Polypeptide synthesis catalyzed by p-hydroxymercuribezoate-modified ribosomes (1980) (0)
- ANALYSIS OF RIBOSOMAL TRANSLOCATION BY DRUGS (1978) (0)
- POLYPEFrIDE SYNTHESIS CATALYZED BY p-HYDROXYMERCURIBENZOATE-MODIFIED RIBOSOMES (0)
- Miscellaneous Inhibitors of Translation (1979) (0)
- Chapter 15. Mechanism of Action of Antibiotics (1970) (0)
- THE RIBOSOMAL PEPTIDYL TRANSFERASE CENTER. POSSIBLE BASES FOR THE COMMON ACTION OF PEPTIDE BOND FORMATION INHIBITORS OF BACTERIAL AND EUKARYOTIC RIBOSOMES (1980) (0)
- The Interaction of Elongation Factor G with N-Acetylphenylalanyl Transfer RNA-Ribosome Complexes ( translocation (0)
- PURIFICATION AND IDENTIFICATION OF THE Pseudomonas aeruginosa DD-ENDOPEPTIDASE AS A PENICILLIN-BINDING PROTEIN (1983) (0)
- INDUCTION OF CELL LYSIS BY MECILLINAM PLUS NOCARDICIN A: ISOLATION AND PROPERTIES OF A TOLERANT MUTANT (1983) (0)
- Labelling of penicillin-binding proteins with a photoreactive peptidoglycan-peptide analogue. (1984) (0)
- Partial crypticity of penicillin-binding protein 1b in purified cell envelopes ofEscherichia coli (1984) (0)
- Inhibition of translation by the fungal toxin cyclopiazonic acid (1983) (0)
- Control of Ribosome Synthesis. An Approach to the Integrated Picture of the Bacterial Control of Ribosome Synthesis, Niels Chr. Kjeldgaard, Ole Maaloe (Eds.). Munksgaard, Copenhagen, Academic Press, London and Basingstoke (1976) (1976) (0)
- A form of elongation factor G insensitive to N-ethyl-maleimide (1976) (0)
- LABELLING AND CROSS-LINKING OF E. COLI PBPs WITH BIS-B-LACTAM AND PHOTOREACTIVE DERIVATIVES OF B-LACTAM ANTIBIOTICS (1983) (0)
- SYNTHESIS CATALYZED BY p-HYDROXYMERCURIBENZOATE-MODIFIED RIBOSOMES (0)
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