Donald W. Paty
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Medical Philosophy
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(Suggest an Edit or Addition)Donald W. Paty's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- New diagnostic criteria for multiple sclerosis: Guidelines for research protocols (1983) (7642)
- Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis (2001) (6788)
- Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis (1993) (1876)
- In vivo visualization of myelin water in brain by magnetic resonance (1994) (864)
- In vivo measurement of T2 distributions and water contents in normal human brain (1997) (758)
- A full genome search in multiple sclerosis (1996) (709)
- MRI in the diagnosis of MS (1988) (707)
- A population-based study of multiple sclerosis in twins. (1986) (638)
- PRISMS-4: Long-term efficacy of interferon-&bgr;-1a in relapsing MS (2001) (567)
- Myelin water imaging in multiple sclerosis: quantitative correlations with histopathology (2006) (432)
- Randomized controlled trial of interferon-beta-1a in secondary progressive MS (2001) (410)
- TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study (1999) (397)
- Cause of death in patients attending multiple sclerosis clinics (1991) (395)
- A Phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses (2006) (372)
- Early onset multiple sclerosis: A longitudinal study (2002) (358)
- Magnetic resonance imaging results of the PRISMS trial: A randomized, double‐blind, placebo‐controlled study of interferon‐β1a in relapsing‐remitting multiple sclerosis (1999) (354)
- Interferon beta-1b in secondary progressive MS (2004) (352)
- TNF neutralization in MS (1999) (348)
- Depression and multiple sclerosis (1996) (346)
- Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis (1993) (335)
- Disability progression in multiple sclerosis is slower than previously reported (2006) (331)
- Recent developments in the assessment of quality of life in Multiple Sclerosis (MS) (1999) (299)
- Serial magnetic resonance scanning in multiple sclerosis: A second prospective study in relapsing patients (1989) (274)
- Multiple sclerosis in childhood: clinical profile in 125 patients. (1987) (255)
- Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease (2003) (180)
- Magnetic resonance imaging of the head in the diagnosis of multiple sclerosis: A prospective 2‐year follow‐up with comparison of clinical evaluation, evoked potentials, oligoclonal banding, and CT (1991) (172)
- Life expectancy in patients attending multiple sclerosis clinics (1992) (171)
- Multiple sclerosis (1988) (161)
- Scales for rating impairment in multiple sclerosis (1988) (155)
- Multiple sclerosis after age 50 (1983) (155)
- Temporal lobe involvement in multiple sclerosis patients with psychiatric disorders. (1987) (153)
- The use of mitoxantrone (Novantrone) for the treatment of multiple sclerosis (2003) (150)
- Spin‐spin relaxation in experimental allergic Encephalomyelitis. Analysis of CPMG data using a non‐linear least squares method and linear inverse theory (1993) (141)
- The evolution of neutralizing antibodies in multiple sclerosis patients treated with interferon β-1b (1999) (138)
- Bilirubin as a potent antioxidant suppresses experimental autoimmune encephalomyelitis: implications for the role of oxidative stress in the development of multiple sclerosis (2003) (134)
- Interferon beta-1b is effective in relapsing-remitting multiple-sclerosis: II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial (2011) (133)
- Sleep disturbance, depression, and lesion site in patients with multiple sclerosis. (1992) (122)
- Dendritic and synaptic pathology in experimental autoimmune encephalomyelitis. (2003) (120)
- Benign versus chronic progressive multiple sclerosis: Magnetic resonance imaging features (1989) (118)
- Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta1a in relapsing-remitting multiple sclerosis. Prevention of Relapses and Disability by Interferon-beta1a Subcutaneously in Multiple Sclerosis. (1999) (118)
- Treatment Optimization in Multiple Sclerosis* (2004) (113)
- CORRELATION BETWEEN NMR SCAN AND BRAIN SLICE DATA IN MULTIPLE SCLEROSIS (1984) (104)
- Pregnancy and multiple sclerosis. A prospective study. (1994) (103)
- A role for natural killer cells in the immunopathogenesis of multiple sclerosis (1998) (103)
- Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis (2001) (102)
- The natural history of primary progressive MS in British Columbia, Canada (2005) (97)
- Concurrence of multiple sclerosis and inflammatory bowel disease. (1989) (97)
- Normal‐appearing white matter in multiple sclerosis has heterogeneous, diffusely prolonged T2 (2002) (94)
- Clinical relapses of multiple sclerosis are associated with ‘novel’ valleys in natural killer cell functional activity (2003) (94)
- Longitudinal analyses of the effects of neutralizing antibodies on interferon beta-1b in relapsing-remitting multiple sclerosis (2004) (91)
- HLA-TYPING IN MULTIPLE SCLEROSIS SIBLING PAIRS (1982) (89)
- Magnetic resonance imaging in the evaluation of clinical trials in multiple sclerosis (1994) (88)
- Megadose corticosteroids in multiple sclerosis (1994) (88)
- Randomized controlled trial of interferon-beta-1a in secondary progressive MS: MRI results (2001) (86)
- Linoleic acid and multiple sclerosis (1984) (85)
- The lesion of multiple sclerosis (1989) (81)
- Systemic lymphoblastoid interferon therapy in chronic progressive multiple Sclerosis. I. Clinical and MRI evaluation (1990) (80)
- The predictive value of cerebrospinal fluid electrophoresis in 'possible' multiple sclerosis. (1983) (78)
- Linoleic acid in multiple sclerosis: Failure to show any therapeutic benefit (1978) (78)
- Magnetic resonance spectroscopy of multiple sclerosis: in-vivo detection of myelin breakdown products (1993) (76)
- Postpartum rubella immunization: association with development of prolonged arthritis, neurological sequelae, and chronic rubella viremia. (1985) (75)
- Neuropsychological Performance in Patients With Mild Multiple Sclerosis (1991) (73)
- DNA length polymorphism 5′ to the myelin basic protein gene is associated with multiple sclerosis (1990) (68)
- Patterns of cognitive impairment in relapsing–remitting multiple sclerosis and their relationship to neuropathology on magnetic resonance images. (1996) (68)
- The natural history of early onset multiple sclerosis: comparison of data from Moscow and Vancouver (2002) (68)
- Magnetic Resonance Imaging in the Assessment of Disease Activity in Multiple Sclerosis (1988) (67)
- Chronic progressive myelopathy: Investigation with CSF electrophoresis, evoked potentials, and CT scan (1979) (64)
- CSF Electrophoresis in One Thousand Patients (1980) (62)
- Biliverdin reductase, a major physiologic cytoprotectant, suppresses experimental autoimmune encephalomyelitis. (2006) (57)
- Evolution of focal and diffuse magnetisation transfer abnormalities in multiple sclerosis (2003) (53)
- Interferon beta-lb is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. 1993 [classical article]. (2001) (53)
- A serial study of peripheral blood T lymphocyte subsets in relapsing–remitting multiple sclerosis (1984) (50)
- The Use of Baclofen in Treatment of Spasticity in Multiple Sclerosis (1979) (49)
- Progressive multiple sclerosis: Abnormal immune functions in vitro and aberrant correlation with enumeration of lymphocyte subpopulations (1986) (48)
- Multiple sclerosis (1988) (47)
- Genetic susceptibility to MS: a second stage analysis in Canadian MS families (2001) (47)
- Familial arteriovenous malformations. Report of four cases in one family. (1985) (47)
- Multiple Sclerosis Quality of Life Inventory (2021) (46)
- Susceptibility to relapsing-progressive multiple sclerosis is associated with inheritance of genes linked to the variable region of the TcR beta locus: use of affected family-based controls. (1998) (45)
- Sexual Dysfunctions in Multiple Sclerosis (1984) (44)
- Chronic parkinsonism secondary to intranasal administration of a product of meperidine-analogue synthesis. (1984) (43)
- Axonal cytoskeleton changes in experimental optic neuritis (1999) (42)
- Guidelines for physicians with patients on IFN beta-1b (1996) (42)
- Clinical and Magnetic Resonance Imaging Changes Correlate in a Clinical Trial Monitoring Cyclosporine Therapy for Multiple Sclerosis (1997) (41)
- Field testing of a minimal record of disability in multiple sclerosis: The United States and Canada (1984) (39)
- Basal ganglia lesions in methanol poisoning: MR appearance. (1988) (39)
- A Sexual Functioning Scale in multiple sclerosis. (1984) (38)
- Intrathecal Fas Ligand Infusion Strengthens Immunoprivilege of Central Nervous System and Suppresses Experimental Autoimmune Encephalomyelitis1 (2002) (37)
- Cognitive impairment and depression in mild multiple sclerosis. (1992) (36)
- Magnetic resonance techniques to monitor the long term evolution of multiple sclerosis pathology and to monitor definitive clinical trials. (1998) (34)
- Measles antibodies as related to HL‐A types in multiple sclerosis (1976) (34)
- Urinary myelin basic protein—like material as a correlate of the progression of multiple sclerosis (1995) (33)
- Ventricular Size, Cognitive Function and Depression in Patients with Multiple Sclerosis (1992) (32)
- Magnetic resonance in multiple sclerosis. (1997) (31)
- The use of MRI as an outcome measure in clinical trials. (2006) (31)
- The lesions of multiple sclerosis. (2002) (29)
- Correlation of clinical features and findings on cranial magnetic resonance imaging with urinary myelin basic protein‐like material in patients with multiple sclerosis (1994) (29)
- Magnetic resonance imaging of experimental allergic encephalomyelitis in primates. (1991) (29)
- Occult Fifth Nerve Dysfunction In Multiple Sclerosis (1981) (28)
- Natural killer (NK) cells in chronic progressive multiple sclerosis patients treated with lymphoblastoid interferon (1988) (26)
- Computer Tomography in Disseminated Sclerosis (1976) (25)
- Systemic lymphoblastoid interferon therapy in chronic progressive multiple sclerosis. II. Immunologic evaluation (1991) (24)
- Neuroimaging in multiple sclerosis. (1984) (24)
- Percutaneous trigeminal rhizotomy. Treatment of trigeminal neuralgia secondary to multiple sclerosis. (1982) (22)
- Carcinomatous neuromyopathy: 1. Electrophysiological studies (1974) (22)
- LINOLEIC ACID IN MULTIPLE SCLEROSIS (1975) (21)
- “Quality of Life” Assessment in Multiple Sclerosis Clinical Trials: Current Status and Strategies for Improving Multiple Sclerosis Clinical Trial Design (1996) (21)
- Models of cognitive deficit and statistical hypotheses: multiple sclerosis, an example. (1993) (20)
- EARLY DETECTION OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS BY MAGNETIC RESONANCE IMAGING (1985) (20)
- Optic neuritis in familial MS (1981) (19)
- Management of relapsing-remitting multiple sclerosis: diagnosis and treatment guidelines (1999) (19)
- Empirical support for psychological profiles observed in multiple sclerosis. (1991) (19)
- Hla in multiple sclerosis Relationship to measles antibody, mitogen responsiveness and clinical course (1977) (18)
- Current Status of Computerization of Multiple Sclerosis Clinical Data for Research in Europe and North America (1995) (18)
- Double-blind trial of linoleic acid in multiple sclerosis. (1983) (17)
- Cerebrospinal fluid concentrations of soluble CD27 in HTLV-I associated myelopathy and multiple sclerosis (1999) (17)
- The multiple sclerosis PRISMS study: Prevention of relapses and disability by interferon beta-1a subcutaneously in multiple sclerosis (1997) (17)
- The interferon‐β1b clinical trial and its implications for other trials (1994) (16)
- Multiple Sclerosis: Assessment of Disease Progression and Effects of Treatment (1987) (16)
- T2 hyperintensities: findings and significance. (2000) (15)
- Effect of interferon beta-1b in MS: assessment of annual accumulation of PD/T2 activity on MRI. UBC MS/MRI Analysis Group and the MS Study Group. (2000) (15)
- The Use of Magnetic Resonance Imaging in Monitoring Interferon Therapy of Multiple Sclerosis (1993) (15)
- ABSENCE OF ANTIBODIES TO HTLV-I AND HTLV-III IN SERA OF PATIENTS WITH MS AND CHRONIC MYELOPATHY (1986) (14)
- Suppression of experimental allergic encephalomyelitis in guinea/pigs by liposome-associated human myelin basic protein. (1981) (13)
- Assessing the Outcome of Experimental Therapies in Multiple Sclerosis Patients (1992) (12)
- The effect of dibutyryl cyclic AMP on restricted replication of rubella virus in rat glial cells in culture. (1983) (12)
- The major histocompatibility complex, the immune system and multiple sclerosis (1979) (12)
- Pathological association and dissociation of functional systems in multiple sclerosis and Huntington's disease. (1997) (12)
- Response to P.H.A. in cancer patients. (1973) (11)
- Chronic progressive myelopathy: investigation with CSF electrophoresis, evoked potentials, and CAT scan. (1978) (11)
- Spongiform Encephalopathy of Long Duration: A Family Study (1980) (11)
- Influence of anesthetic agents on blood-brain barrier function during acute hypertension. (1981) (10)
- Natural killer cells in relapsing-remitting MS: effect of treatment with interferon beta-1B. (1999) (10)
- Trial measures in multiple sclerosis: The use of magnetic resonance imaging in the evaluation of clinical trials (1988) (10)
- MRI in monitoring the treatment of multiple sclerosis: concerted action guidelines. (1992) (9)
- HLA-D typing with an association of Dw2 and absent immune responses towards herpes simplex (type i) antigen in multiple sclerosis. (1977) (9)
- Interferons in relapsing remitting multiple sclerosis (2003) (9)
- An encephalitogenic basic protein from human peripheral nerve. (1971) (9)
- Conventional MRI Techniques in Multiple Sclerosis (2005) (8)
- Study of alleles of the second complement component (C2) on Canadian HLA haplotypes. (2008) (8)
- CSF Electrophoresis: An Adaptation Using Cellulose Acetate for the Identification of Oligoclonal Banding (1978) (8)
- Ocular bobbing in bromism (1972) (8)
- Immunology of multiple sclerosis. (1971) (8)
- Immune function in MS: Correlation with disease activity as revealed by MRI (1987) (7)
- MRI as a method to reveal in-vivo pathology in MS. (1997) (7)
- Carcinomatous neuromyopathy: 2. Immunological studies (1974) (7)
- Magnetic Resonance Imaging in Demyelination (1989) (7)
- A two-label microfluorometric analysis of the expression of OKT5 and Leu 2a antigens on peripheral blood lymphocytes in patients with multiple sclerosis (1984) (7)
- MULTIPLE-SCLEROSIS (MS) PRESENTING IN PATIENTS OVER 50 YEARS OF AGE (1981) (7)
- Assessment of multiple sclerosis lesions by magnetic resonance imaging. (1987) (7)
- Analysis of effector CD4 (OX‐40+) and CD8 (CD45RA+ CD27‐) T lymphocytes in active multiple sclerosis (2000) (7)
- Counteracting effect of IFN-beta on IFN-gamma-induced proliferation of human astrocytes in culture. (1996) (6)
- Differentiation of glioblasts from adult brain (1983) (6)
- Spinal Cord Swelling in Multiple Sclerosis (1981) (6)
- HL-A Frequencies in Patients with Multiple Sclerosis (1974) (6)
- Treatment of experimental allergic encephalomyelitis in the rabbit. (1972) (6)
- Studies in familial multiple sclerosis. (1980) (5)
- Use of background interference procedure to assess visual retention deficits in multiple-sclerosis, psychiatric, and brain-damaged patients. (1985) (5)
- Treatment of multiple sclerosis with interferon beta-1b (1997) (5)
- New perspectives in multiple sclerosis. (1989) (5)
- Biologic versus clinical MS (1989) (5)
- CAUSES OF DEATH IN MULTIPLE-SCLEROSIS (1985) (5)
- Recombinant human interferon beta in the treatment of relapsing-remitting and secondary progressive multiple sclerosis. (1995) (5)
- MS COSTAR: A Computerized Record for Use in Clinical Research in Multiple Sclerosis: (1993) (5)
- Ultrasound measurement of brain atrophy in multiple sclerosis. (2000) (4)
- MARKERS AND PROGNOSIS IN MULTIPLE-SCLEROSIS (1983) (4)
- Fluorescence-activated cell sorter analysis of bulk-isolated porcine oligodendrocytes (1986) (4)
- Chapter 18 Multiple Sclerosis with Early and Late Disease Onset (2003) (4)
- HLA antigens and mitogen responsiveness in multiple sclerosis. (1977) (4)
- Defining the neurological basis of the Gulf War syndrome. (2000) (3)
- Biologic versus clinical MS (1989) (3)
- Letter: Acupuncture and multiple sclerosis. (1974) (3)
- Multiple sclerosis: recent advances in diagnosis clinical immunology and virology. (1977) (3)
- Use of magnetic resonance imaging in the diagnosis of multiple sclerosis. Policy statement of the National Multiple Sclerosis Society, New York (1986) (3)
- An HLA-D-linked low response to polyclonal B-cell activation in multiple sclerosis. (1978) (3)
- Long term management of multiple sclerosis (1994) (3)
- MRI in MS diagnosis (1987) (3)
- Off the mainstream: The Multiple Sclerosis Diet Book: a Low-Fat Diet for the Treatment of M.S (1988) (2)
- Morbilliform rash secondary to baclofen ingestion (1983) (2)
- A Prospective Study of MRI in Multiple Sclerosis (1987) (2)
- Carcinomatous neuromyopathy. 2. Immunological studies. An electrophysiological and immunological study of patients with carcinoma of the lung. (1974) (2)
- Anticytokine antibodies in beta‐interferon‐treated patients (1998) (2)
- Alpha Methyldopahydrazine as an Adjunct to Levodopa Therapy in Parkinson’s Disease (1975) (2)
- Importance of magnetic resonance imaging and gadolinium enhancement (1996) (2)
- Magnetic resonance imaging as an outcome measure in the treatment of multiple sclerosis: results of the interferon beta trial. (1995) (2)
- Magnetic Resonance Imaging (MRI) As an Outcome Measure in Multiple Sclerosis (1993) (2)
- The Mayo Clinic–Canadian cooperative trial of sulfasalazine in active multiple sclerosis (1999) (1)
- Inter-rater variability on multiple sclerosis disability scales in a blinded, prospective clinical trial (1989) (1)
- MS MORTALITY - REPLY (1992) (1)
- MRI‐PATHOLOGICAL CORRELATIONS IN MS: 107 (1987) (1)
- HERPES LABIALIS AND MULTIPLE SCLEROSIS (1976) (1)
- MS COSTAR: A Computerized Record for Use in Clinical Research in Multiple Sclerosis (1993) (1)
- DYSFUNCTION OF THE BLOOD-BRAIN BARRIER IN THE PATHOGENESIS OF MULTIPLE SCLEROSIS (1)
- Cell-mediated lympholysis--problems and possibilities in defining specificities. (1977) (1)
- Multiple sclerosis. (1986) (1)
- CLINICAL PROGNOSTIC MARKERS IN MULTIPLE-SCLEROSIS (1979) (1)
- Magnetic resonance imaging in the diagnosis and follow-up of patients with multiple sclerosis. (1992) (1)
- Alkaline isoelectric focusing in polyacrylamide gel of cerebrospinal fluid in multiple sclerosis. (1979) (1)
- Multiple Sclerosis: A Guide for the Newly Diagnosed (1997) (1)
- Patient selection and criteria. (1983) (1)
- Multiple Sclerosis, Diagnosis (2003) (1)
- Long term culture of human oligodendrocytes in serum-free chemically defined medium. (1984) (1)
- Longitudinal prospective evaluation of treatment effects, MRI and neutralizing antibodies in multiple sclerosis patients treated long-term with interferon-β-1b (Betaseron) (2001) (1)
- HLA-Dw2-related hyporesponsiveness to herpes simplex antigen in multiple sclerosis. (1977) (1)
- The interferon-beta 1b clinical trial and its implications for other trials. (1994) (1)
- Funding of drug treatment of multiple sclerosis should not be delayed (1997) (1)
- Conference Report: International Symposium on Multiple Sclerosis University of Western Ontario May 3-5, 1981 (1981) (1)
- Glomus of the choroid plexus: the normal spin-echo appearance on magnetic resonance imaging. (1990) (1)
- MS mortality (1992) (0)
- IGG secretion in vitro in relation with antibody status in MS patients treated with interferon beta 1B (1997) (0)
- Encephalomyelitis and Suppresses Experimental Autoimmune Immunoprivilege of Central Nervous System Intrathecal Fas Ligand Infusion Strengthens (2002) (0)
- Analysis of CD4+CD134 (Ox-49)+ helper- and CD8+CD27-cytotoxic- effector T-cells in multiple sclerosis (1998) (0)
- A longitudinal study of T cell subset surface antigen expression in multiple sclerosis. (1984) (0)
- Differences in the incidence of demyelinating diseases appear to be linked to ethnic factors (1995) (0)
- In multiple sclerosis treated with interferon beta 1B some reduction of in vitro IGG secretion is seen over 2 years follow-up (1995) (0)
- The Correlation Between Magnetic Resonance Imaging Abnormalities and other Aspects of Multiple Sclerosis with Particular Emphasis on Therapeutic Trials (1994) (0)
- Reply from the Authors to Drs. Milanese, Savettieri, and Terizan (1996) (0)
- The Short T2 Component in Normal-Appearing White Matter in Multiple Sclerosis (2004) (0)
- Development of a computerized neurological decision support system (1991) (0)
- Letter: Herpes labialis and multiple sclerosis. (1976) (0)
- Book ReviewMultiple Sclerosis: Psychological and social aspects (1984) (0)
- AN ATLAS OF MULTIPLE SCLEROSIS. 1998. Edited by Charles Poser. Published by Parthenon Publishing. 129 pages C$101.40 approx. (2000) (0)
- Letter: Linoleic acid in multiple sclerosis. (1975) (0)
- andimmunological study ofpatients with carcinoma ofthelung (1974) (0)
- New Perspectives in Multiple Sclerosis SUMMARY (2008) (0)
- Multiple Sclerosis in Clinical Practice (2001) (0)
- Neuroimaging in infections and demyelinating disease. (1991) (0)
- IFNB IN MS. AUTHORS' REPLY (1996) (0)
- Immunotherapy for MS: clinical aspects and trials (1995) (0)
- MS mortality. Replies (1992) (0)
- Sexual Functioning Scale (2018) (0)
- Magnetic Resonance Imaging Techniques in Phase III Clinical Trials in Multiple Sclerosis (1999) (0)
- Imaging for clinical chemists (1985) (0)
- Book ReviewMcAlpine's Multiple Sclerosis (1985) (0)
- Interferon β-1a prevented the development of clinically definite multiple sclerosis after a first demyelinating event (2001) (0)
- Treatment of multiple sclerosis with interferon beta-1b - Reply (1997) (0)
- TREATMENT OF MULTIPLE SCLEROSIS WITH INTERFERON BETA-1B. AUTHORS' REPLY (1997) (0)
- PET AND NMR . Series: Neurology and Neurobiology, Volume 21. Edited by Leontino Battistin and Franz Gerstenbrand. Published by Alan R. Liss, Inc., New York, 518 pages. $119Cdn approx. (1988) (0)
- Book ReviewFundamentals of Neurophysiology (1986) (0)
- 15 – MRI in Multiple Sclerosis (2000) (0)
- Dietary supplementation with polyunsaturated fatty acids in acute remitting multiple sclerosis (1984) (0)
- Cerebrospinal fluid levels of soluble CD27 correlate with disease activity in multiple sclerosis and with disease state in HTLV-1 associated HAM/TSP (1998) (0)
- ANTICYTOKINE ANTIBODIES IN BETA-INTERFERON-TREATED PATIENTS. AUTHOR'S REPLY (1998) (0)
- A serial tap method for removal of peritoneal exudate cells from guinea pigs. (1975) (0)
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