Dai Fukumura
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Computer Science
Dai Fukumura's Degrees
- PhD Computer Science University of Tokyo
- Masters Artificial Intelligence Stanford University
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Dai Fukumura's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Photodynamic therapy for cancer (2003) (4291)
- Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (1998) (2183)
- Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. (1995) (1719)
- Normalization of the vasculature for treatment of cancer and other diseases. (2011) (1307)
- Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. (1997) (1291)
- Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. (2004) (1263)
- The role of nitric oxide in tumour progression (2006) (1069)
- Compact high-quality CdSe-CdS core-shell nanocrystals with narrow emission linewidths and suppressed blinking. (2013) (1057)
- Tumor Induction of VEGF Promoter Activity in Stromal Cells (1998) (992)
- Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability (2001) (958)
- Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges (2018) (926)
- Multistage nanoparticle delivery system for deep penetration into tumor tissue (2011) (894)
- Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner (2012) (873)
- Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy (2012) (746)
- Engineering vascularized tissue (2005) (710)
- Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging (2009) (691)
- Tissue engineering: Creation of long-lasting blood vessels (2004) (680)
- Tumour biology: Herceptin acts as an anti-angiogenic cocktail (2002) (673)
- Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. (2007) (661)
- Dissecting tumour pathophysiology using intravital microscopy (2002) (612)
- Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (vol 394, pg 485, 1998) (1998) (579)
- Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. (1998) (559)
- Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. (2008) (555)
- Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize (2007) (532)
- Malignant cells facilitate lung metastasis by bringing their own soil (2010) (489)
- Vascular normalization as an emerging strategy to enhance cancer immunotherapy. (2013) (485)
- Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo (2005) (438)
- The biology of brain metastases—translation to new therapies (2011) (432)
- Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. (2001) (416)
- Next-generation in vivo optical imaging with short-wave infrared quantum dots (2017) (407)
- Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration. (2011) (403)
- Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre‐Clinical Models (2010) (398)
- In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy (2001) (394)
- Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green (2017) (389)
- CXCL12 (SDF1α)-CXCR4/CXCR7 Pathway Inhibition: An Emerging Sensitizer for Anticancer Therapies? (2011) (388)
- Consensus guidelines for the use and interpretation of angiogenesis assays (2018) (370)
- Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. (1999) (358)
- Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. (2002) (357)
- Paracrine Regulation of Angiogenesis and Adipocyte Differentiation During In Vivo Adipogenesis (2003) (356)
- Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. (2006) (337)
- Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. (2008) (335)
- A nanoparticle size series for in vivo fluorescence imaging. (2010) (327)
- Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions. (2010) (325)
- Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo (2007) (304)
- Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. (2009) (303)
- In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy (2001) (282)
- Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. (2016) (269)
- Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1alpha--> hypoxia response element--> VEGF cascade differentially regulates vascular response and growth rate in tumors. (2000) (269)
- Acidic Extracellular pH Induces Vascular Endothelial Growth Factor (VEGF) in Human Glioblastoma Cells via ERK1/2 MAPK Signaling Pathway (2002) (266)
- Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival (2016) (263)
- Compact biocompatible quantum dots via RAFT-mediated synthesis of imidazole-based random copolymer ligand. (2009) (262)
- Cancer imaging by optical coherence tomography: preclinical progress and clinical potential (2012) (256)
- Impaired lymphatic contraction associated with immunosuppression (2011) (243)
- Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages (2016) (239)
- Solid stress and elastic energy as measures of tumour mechanopathology (2016) (238)
- Role of eNOS in neovascularization: NO for endothelial progenitor cells. (2004) (232)
- Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. (1997) (231)
- Magneto-Fluorescent Core-Shell Supernanoparticles (2014) (212)
- Helicobacter pylori-associated ammonia production enhances neutrophil-dependent gastric mucosal cell injury. (1992) (209)
- Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma (2013) (209)
- A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer (2016) (207)
- Genetic evidence for a tumor suppressor role of HIF-2alpha. (2005) (192)
- InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared. (2009) (174)
- Role of host microenvironment in angiogenesis and microvascular functions in human breast cancer xenografts: mammary fat pad versus cranial tumors. (2002) (168)
- Role of nitric oxide in angiogenesis and microcirculation in tumors (1998) (167)
- NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels. (2005) (167)
- Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation (2011) (166)
- Imaging angiogenesis and the microenvironment (2008) (165)
- Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors. (2003) (164)
- Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. (1997) (163)
- Arginine dependence of tumor cells: targeting a chink in cancer’s armor (2016) (162)
- Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases (2016) (162)
- Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors. (2006) (160)
- Vascular accumulation of a novel photosensitizer, MV6401, causes selective thrombosis in tumor vessels after photodynamic therapy. (2002) (155)
- Peritumor Lymphatics Induced by Vascular Endothelial Growth Factor-C Exhibit Abnormal Function (2004) (154)
- Perivascular nitric oxide gradients normalize tumor vasculature (2008) (151)
- Scaling rules for diffusive drug delivery in tumor and normal tissues (2011) (149)
- In vivo wide-area cellular imaging by side-view endomicroscopy (2010) (145)
- Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells (2013) (138)
- Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2 (2018) (136)
- In vivo imaging of tumors. (2010) (135)
- Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain. (1995) (135)
- Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks in vivo (2010) (134)
- Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases (2012) (133)
- Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood–tumor barrier disruption (2018) (131)
- Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis. (2006) (130)
- Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy. (2000) (129)
- Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis. (2009) (127)
- Angiopoietin-2 Interferes with Anti-VEGFR2–Induced Vessel Normalization and Survival Benefit in Mice Bearing Gliomas (2010) (126)
- Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis. (2011) (122)
- Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. (2016) (122)
- Emerging strategies for treating brain metastases from breast cancer. (2015) (119)
- Pancreas Microenvironment Promotes VEGF Expression and Tumor Growth: Novel Window Models for Pancreatic Tumor Angiogenesis and Microcirculation (2001) (118)
- Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy (2017) (112)
- Omeprazole attenuates oxygen-derived free radical production from human neutrophils. (1996) (111)
- Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages (2015) (108)
- Cationic Nanoparticles Have Superior Transvascular Flux into Solid Tumors: Insights from a Mathematical Model (2012) (106)
- Tumor–host interactions in the gallbladder suppress distal angiogenesis and tumor growth: Involvement of transforming growth factor β1 (1999) (106)
- Rebamipide, a novel antiulcer agent, attenuates Helicobacter pylori induced gastric mucosal cell injury associated with neutrophil derived oxidants. (1994) (105)
- Hypoxia-Induced Activation of p38 Mitogen-Activated Protein Kinase and Phosphatidylinositol 3′-Kinase Signaling Pathways Contributes to Expression of Interleukin 8 in Human Ovarian Carcinoma Cells (2004) (102)
- Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib (2008) (101)
- Endothelial Nitric Oxide Synthase Regulates Microlymphatic Flow via Collecting Lymphatics (2004) (101)
- Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy. (2015) (99)
- Mice Lacking E‐Selection Show Normal Numbers of Rolling Leukocytes but Reduced Leukocyte Stable Arrest on Cytokine‐Activated Microvascular Endothelium (1998) (99)
- Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A. (2001) (99)
- PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity (2016) (98)
- Targeting tumor vasculature and cancer cells in orthotopic breast tumor by fractionated photosensitizer dosing photodynamic therapy. (2002) (97)
- Quantum dot/antibody conjugates for in vivo cytometric imaging in mice (2015) (97)
- Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity (2018) (96)
- Secreted Gaussia Luciferase as a Biomarker for Monitoring Tumor Progression and Treatment Response of Systemic Metastases (2009) (94)
- correction: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (1998) (94)
- Blockade of VEGFR2 and Not VEGFR1 Can Limit Diet-Induced Fat Tissue Expansion: Role of Local versus Bone Marrow-Derived Endothelial Cells (2009) (92)
- Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. (2013) (91)
- Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors. (2015) (89)
- C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells (2010) (88)
- Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium (2018) (88)
- Differential vascular and transcriptional responses to anti-vascular endothelial growth factor antibody in orthotopic human pancreatic cancer xenografts. (2003) (85)
- Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models. (2006) (85)
- Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in tumor vascular networks (2010) (84)
- Nitric oxide mediates Kupffer cell-induced reduction of mitochondrial energization in hepatoma cells: a comparison with oxidative burst. (1993) (82)
- Nitric oxide mediates lipopolysaccharide‐induced alteration of mitochondrial function in cultured hepatocytes and isolated perfused liver (1993) (80)
- The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation (2017) (80)
- Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer (2017) (79)
- Fatty acid synthesis is required for breast cancer brain metastasis (2021) (78)
- Benefits of vascular normalization are dose and time dependent--letter. (2013) (78)
- PDGF-D Improves Drug Delivery and Efficacy via Vascular Normalization, But Promotes Lymphatic Metastasis by Activating CXCR4 in Breast Cancer (2011) (78)
- Spatial charge configuration regulates nanoparticle transport and binding behavior in vivo. (2013) (75)
- Transgenic Mice for cGMP Imaging (2013) (75)
- Irradiation of a primary tumor, unlike surgical removal, enhances angiogenesis suppression at a distal site: potential role of host-tumor interaction. (2000) (72)
- VEGFR1-activity-independent metastasis formation (2009) (72)
- Leukocyte-endothelial adhesion and angiogenesis in tumors (1996) (70)
- Wide-field three-photon excitation in biological samples (2016) (63)
- Cells shed from tumours show reduced clonogenicity, resistance to apoptosis, and in vivo tumorigenicity (1999) (63)
- Oxiradical-dependent photoemission induced by a phacoemulsification probe. (1992) (61)
- Influence of tumor cell and stroma sensitivity on tumor response to radiation. (2007) (61)
- Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. (2016) (59)
- Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies (2019) (59)
- Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors (2015) (59)
- Enhanced levels of chemiluminescence and platelet activating factor in urease-positive gastric ulcers. (1996) (55)
- Differential Transplantability of Tumor-Associated Stromal Cells (2004) (53)
- A mathematical model of murine metabolic regulation by leptin: energy balance and defense of a stable body weight. (2009) (53)
- Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas (2021) (51)
- VEGFR1 Activity Modulates Myeloid Cell Infiltration in Growing Lung Metastases but Is Not Required for Spontaneous Metastasis Formation (2009) (51)
- Increased nitric oxide synthase activity as a cause of mitochondrial dysfunction in rat hepatocytes: roles for tumor necrosis factor α (1996) (50)
- Obesity and Cancer: An Angiogenic and Inflammatory Link (2016) (50)
- Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment (2012) (49)
- Multistage nanoparticles for improved delivery into tumor tissue. (2012) (48)
- Evolution of Oxygen and Glucose Concentration Profiles in a Tissue-Mimetic Culture System of Embryonic Stem Cells (2006) (47)
- Roles of ET-1 in endotoxin-induced microcirculatory disturbance in rat small intestine. (1996) (42)
- Intravital demonstration of sequential migration process of lymphocyte subpopulations in rat Peyer's patches. (1995) (41)
- Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity (2015) (41)
- Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo. (2009) (40)
- Attenuation of endotoxin-induced intestinal microcirculatory damage by eicosapentanoic acid. (1993) (38)
- Histopathologic findings and establishment of novel tumor lines from spontaneous tumors in FVB/N mice. (2008) (36)
- Lack of lymphatic vessel phenotype in LYVE‐1/CD44 double knockout mice (2009) (35)
- Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines (2020) (34)
- Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts. (2003) (33)
- A Homing System Targets Therapeutic T-cells to Brain Cancer (2018) (33)
- Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. (2009) (33)
- Omeprazole attenuates neutrophil–endothelial cell adhesive interaction induced by extracts of Helicobacter pylori (1999) (33)
- Normalization of the tumor vasculature through oncogenic inhibition: An emerging paradigm in tumor biology (2012) (31)
- Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy (2020) (30)
- Targeting PDGF Signaling in Carcinoma-Associated Fibroblasts Controls Cervical Cancer in Mouse Model (2008) (30)
- Exercise Training Improves Tumor Control by Increasing CD8+ T-cell Infiltration via CXCR3 Signaling and Sensitizes Breast Cancer to Immune Checkpoint Blockade (2021) (30)
- Mechanisms of endothelin-induced macromolecular leakage in microvascular beds of rat mesentery. (1993) (29)
- Ischemic bowel necrosis induced by endothelin-1: an experimental model in rats. (1991) (29)
- Small blood vessel engineering. (2007) (28)
- Visualization of oxidative processes at the cellular level during neutrophil‐mediated cytotoxicity against a human hepatoma cell line, HCC‐M (1992) (26)
- Role of platelet activating factor on the fibrinolytic activation in the pathogenesis of gastric mucosal damage induced by endothelin-1. (1992) (26)
- Spontaneous nonthymic tumors in SCID mice. (2011) (26)
- Oxyradical generation from leukocytes during endotoxin-induced microcirculatory disturbance in rat mesentery--attenuating effect of cetraxate. (1993) (25)
- A transient parabiosis skin transplantation model in mice (2012) (23)
- Vascular diseases await translation of blood vessels engineered from stem cells (2015) (23)
- Role in nitric oxide in Kupffer cell–mediated hepatoma cell cytotoxicity in vitro and ex vivo (1996) (23)
- Rat Kupffer cell-derived nitric oxide suppresses proliferation and induces apoptosis of syngeneic hepatoma cells. (1996) (22)
- Molecular regulation of microlymphatic formation and function: role of nitric oxide. (2005) (21)
- Increased nitric oxide synthase activity as a cause of mitochondrial dysfunction in rat hepatocytes: roles for tumor necrosis factor alpha. (1996) (21)
- Kupffer cell-mediated oxidative stress on colon cancer cell line visualized by digital imaging fluorescence microscopy. (1991) (20)
- Correlative intravital imaging of cGMP signals and vasodilation in mice (2014) (20)
- A cerebellar window for intravital imaging of normal and disease states in mice (2017) (19)
- MicroRNA-378 enhances radiation response in ectopic and orthotopic implantation models of glioblastoma (2017) (18)
- Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy (2021) (17)
- Helicobacter pylori elicits gastric mucosal cell damage associated with neutrophil-derived toxic oxidants (1993) (17)
- Fluorographic study on the oxidative stress in the process of gastric mucosal injury: Attenuating effect of Vitamin E (1993) (16)
- Kupffer cell-mediated cytotoxicity against hepatoma cells occurs through production of nitric oxide and adhesion via ICAM-1/CD18. (1996) (16)
- Mast Cells Contribute to Radiation-Induced Vascular Hyperpermeability (2016) (16)
- Transparent Window Models and Intravital Microscopy: Imaging Gene Expression, Physiological Function, and Drug Delivery in Tumors (2001) (15)
- Role in nitric oxide in Kupffer cell-mediated hepatoma cell cytotoxicity in vitro and ex vivo. (1996) (15)
- Corrigendum: Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. (2016) (15)
- Evidence of direct interaction between Kupffer cells and colon cancer cells: an ultrastructural study of the co-culture. (2008) (14)
- Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer (2019) (14)
- Transparent Window Models and Intravital Microscopy (2002) (13)
- Vascular Endothelial Growth Factor (VEGF)-C Differentially Affects Tumor Vascular Function and Leukocyte Recruitment: Role of VEGF-Receptor 2 and Host VEGF-A 1 (2001) (13)
- Studying primary tumor–associated fibroblast involvement in cancer metastasis in mice (2012) (13)
- Ly 6 Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR 2 cancer therapy (2019) (13)
- A phase II study of preoperative (preop) bevacizumab (bev) followed by dose-dense (dd) doxorubicin (A)/cyclophosphamide (C)/paclitaxel (T) in combination with bev in HER2-negative operable breast cancer (BC). (2012) (12)
- Role of Microenvironment on Gene Expression, Angiogenesis and Microvascular Function in Tumors (2005) (12)
- IL-1 is an important mediator for microcirculatory changes in endotoxin-induced intestinal mucosal damage (1996) (12)
- Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model (2021) (12)
- Quantitative analysis of mesenteric microcirculatory disturbances induced by autonomic nervous irritation. (1992) (11)
- An isolated tumor perfusion model in mice (2012) (11)
- Measuring Vascular Permeability In Vivo. (2016) (11)
- Rat Kupffer cell-derived nitric oxide modulates induction of lymphokine-activated killer cell. (1995) (11)
- Active oxidants mediate IFN-alpha-induced microvascular alterations in rat mesentery. (1997) (11)
- Advances in Brief Hypoxia and Acidosis Independently UpRegulate Vascular Endothelial Growth Factor Transcription in Brain Tumors in Vivo 1 (2001) (10)
- Longitudinal Tracing of Spontaneous Regression and Anti-angiogenic Response of Individual Microadenomas during Colon Tumorigenesis (2015) (10)
- Gastric microcirculatory disturbance and behaviour of leucocytes after thermal injury: Intravital observation of arteriovenous shunting channels in the gastric submucosal layer (1995) (10)
- Measuring angiogenesis and hemodynamics in mice. (2013) (10)
- In vitro and in vivo quantification of adhesion between leukocytes and vascular endothelium. (1999) (10)
- Green fluorescent protein (GFP)-expressing tumor model derived from a spontaneous osteosarcoma in a vascular endothelial growth factor (VEGF)-GFP transgenic mouse. (2005) (9)
- Inhibitions of platelet-activating factor production and granulocyte oxidative activation by Rikkunshi-To in the process of gastric mucosal injury (1995) (9)
- Mammary fat pad tumor preparation in mice. (2012) (9)
- Oxidative stress in gastric mucosal injury: Role of platelet-activating factor-activated granulocytes (1995) (9)
- Transparent Window Models and Intravital Microscopy: Imaging Gene Expression, Physiological Function and Therapeutic Effects in Tumors (2011) (9)
- The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy. (2022) (8)
- Verotoxin induces hemorrhagic lesions in rat small intestine (1994) (7)
- Blockade of VEGFR 2 and Not VEGFR 1 Can Limit Diet-Induced Fat Tissue Expansion : Role of Local versus Bone Marrow-Derived Endothelial Cells (2009) (7)
- Degranulation of mast cells correlates to radiation-induced increase of vascular permeability (2000) (7)
- Attenuating Effect of Antithrombin III on the Fibrinolytic Activation and Microvascular Derangement in Rat Gastric Mucosa (1994) (6)
- Influence of the site of human gallbladder xenograft (Mz-ChA-1) on angiogenesis at the distant site. (2004) (6)
- Measuring vascular permeability in mice. (2013) (6)
- Nitric Oxide Mediates Vasoactive Effects of Endothelin-3 on Rat Mesenteric Microvascular Beds in Vivo (1993) (6)
- From the Guest Editors: Role of Tumor Microenvironment in Tumor Progression and Treatment Response: A 30 Years' Journey. (2015) (6)
- NAD+-mediated rescue of prenatal forebrain angiogenesis restores postnatal behavior (2020) (6)
- Involvement of platelet-activating factor in endothelin-induced vascular smooth muscle cell contraction. (1991) (6)
- Correction for Liao et al., Impaired lymphatic contraction associated with immunosuppression (2016) (5)
- cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice (2019) (5)
- Role of endothelin‐1 in repeated electrical stimulation‐induced microcirculatory disturbance and mucosal damage in rat stomach (1996) (5)
- Amelioration of Chronic Inflammation by Ingestion of Elemental Diet in a Rat Model of Granulomatous Enteritis (1997) (5)
- Lymphangiography of the mouse ear. (2012) (4)
- Measuring interstitial diffusion, convection, and binding parameters in mouse tumors. (2013) (4)
- Intravital observation on the endothelin-induced hemodynamic changes in rat intestinal microvascular beds (1991) (4)
- Anti-VEGFR-3 therapy and lymph node metastasis [corrected]. (2007) (4)
- Corneal pocket assay in rabbits. (2012) (3)
- Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression-associated genes in locally advanced pancreatic cancer (2022) (3)
- Abstract 548: Multistage nanoparticle delivery system for deep penetration into solid tumor (2011) (3)
- Measurement of physiological parameters in tumors in vivo using MPLSM (2001) (3)
- Tissue-type plasminogen activator of colonic mucosa in ulcerative colitis. Evidence of endothelium-derived fibrinolytic activation. (1992) (3)
- Angiogenesis in Development, Disease, and Regeneration (2009) (3)
- Bile acid‐induced depolarization of mitochondrial membrane potential preceding cell injury in cultured gastric mucosal cells (1995) (3)
- Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction (2022) (2)
- Lessons From 30 Years of Teaching About the Microenvironment of Tumors. (2015) (2)
- Role of endothelin in the pathogenesis of gastric mucosal hemorrhagic lesion. (1991) (2)
- Role of VEGF-Receptor 2 and Host VEGF-A Affects Tumor Vascular Function and Leukocyte Recruitment: Vascular Endothelial Growth Factor (VEGF)-C Differentially (2001) (2)
- Measuring interstitial pH and pO2 in mouse tumors. (2013) (2)
- Evidence for bone marrow-derived endothelial cells incorporation into perfused blood vessels in tumors (2006) (2)
- Novel function of RANKL: eNOS activator (2007) (2)
- Author Correction: Fatty acid synthesis is required for breast cancer brain metastasis (2021) (2)
- Modes of Neovascularization in Tumors and Clinical Translation of Antiangiogenic Therapy (2014) (2)
- Next-generation optical imaging with short-wave infrared quantum dots. (2017) (2)
- Liver tumor preparation in mice. (2012) (2)
- Design rules for cancer nanomedicines (2012) (2)
- Optical Microscopy in Small Animal Research (2007) (2)
- Abstract LB-203: Obesity promotes resistance to anti-VEGF therapy in breast cancer via pro-inflammatory and angiogenic pathways (2015) (2)
- Pancreatic tumor preparation in mice. (2012) (2)
- Rabbit ear chambers. (2012) (2)
- Abstracts from the International Society for Therapeutic Ultrasound Conference 2017 (2018) (2)
- Uncovering Tumor Biology by Intravital Microscopy (2014) (2)
- Lung window preparation in mice. (2013) (2)
- Lymphangiography of the mouse tail. (2012) (2)
- Tumor Angiogenesis Regulated by Gaseous Molecules in Tumor Microenvironment: Oxygen, pH, and Nitric Oxide (2005) (1)
- Combined Angiotensin Receptor Blocker Losartan and the CXCR4 Inhibitor AMD3100 Increases the Efficacy of Radiotherapy in a Metastatic Osteosarcoma Mouse Model (2018) (1)
- Abstract C043: Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression-associated genes in locally advanced pancreatic cancer (2022) (1)
- Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors (2013) (1)
- Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling Inhibition (2022) (1)
- Erratum: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (Nature (1998) 394 (485-490)) (1998) (1)
- Abstract C1: Functional normalization of the breast cancer vasculature through activation of Tie2 using a vascular-endothelial protein tyrosine phosphatase inhibitor. (2013) (1)
- Abstract P3-12-03: Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. (2012) (1)
- Measuring leukocyte-endothelial interactions in mice. (2013) (1)
- Abstract T P225: cGMP-Dependent Protein Kinase I in Smooth Muscle Cells Protects Against Stroke Injury in Mice (2014) (1)
- Abstract PR06: VEGF-targeted therapy induces extracellular matrix remodeling and increases mechanical barriers to therapy in colorectal cancer liver metastases (2017) (1)
- Abstract 898: Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy (2016) (1)
- Dual near‐infrared II laser modulates the cellular redox state of T cells and augments the efficacy of cancer immunotherapy (2022) (1)
- Erratum: Visualization of oxidative processes at the cellular level during neutrophil-mediated cytotoxicity against a human hepatoma cell line, HCC-M (International Journal of Cancer, 51, 124-129 (1992)) (1992) (1)
- Abstract 5008: The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation (2017) (1)
- Retraction Note: A homing system targets therapeutic T cells to brain cancer (2019) (1)
- Analysis of cGMP signalling with transgenic mice expressing FRET-based cGMP sensors (2013) (1)
- Tissue-type plasminogen activator of colonic mucosa in ulcerative colitis (1992) (1)
- Microcirculation of Human Colon Adenocarcinoma (2007) (1)
- Morphometric analysis of mesenteric mast cell degranulation induced by autonomic nervous irritation (1993) (1)
- Spatial heterogeneity of mucosal blood flow during ischemia-reperfusion injury of rat stomach investigated by laser Doppler perfusion imaging (1995) (1)
- Vascular normalization: a strategy to recondition the tumor immune microenvironment (2013) (1)
- Abstract LB-363: Inhibition of placental growth factor (PlGF) leads to regression of medulloblastoma (2010) (1)
- Hormone Ablation , and Chemotherapy Vascular Endothelial Growth Factor Receptor-2 Blockade , Tumor Oxygenation in Hormone-Dependent Tumors During Updated (2000) (1)
- Mammary fat pad chamber preparation in mice. (2012) (1)
- Advances in Brief Vascular Endothelial Growth Factor ( VEGF ) Modulation by Targeting Hypoxia-inducible Factor-1 a 3 Hypoxia Response Element 3 VEGF Cascade Differentially Regulates Vascular Response and Growth Rate in Tumors 1 (2000) (1)
- Implications of a granulocyte‐high glioblastoma microenvironment in immune suppression and therapy resistance† (2021) (1)
- The orthotopic microenvironment promotes tumor growth and VEGF121 expression in human pancreatic adenocarcinoma (2000) (1)
- Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy (2020) (0)
- Abstract 3987: Solid stress and elastic energy as measures of tumor mechanopathology (2017) (0)
- Cationic Nanoparticles Have Superior Transvascular Flux into Solid Tumors: Insights from a Mathematical Model (2012) (0)
- Abstract LB557: Multiphoton phosphorescence quenching microscopy reveals kinetics of tumor oxygenation during anti-angiogenesis and angiotensin signaling inhibition (2022) (0)
- CADD-32. MECHANISMS OF ENHANCED DRUG DELIVERY IN BRAIN TUMORS WITH FOCUSED ULTRASOUND-INDUCED TRANSIENT BLOOD-TUMOR BARRIER DISRUPTION (2018) (0)
- Methods to improve anti-angiogenic therapy and immunotherapy (2018) (0)
- II . ROLE OF ABNORMAL VASCULATURE IN TUMOR PROGRESSION AND TREATMENT RESISTANCE A . The Abnormal Structure of Tumor Vasculature (2011) (0)
- Erratum: Quantum dot/antibody conjugates for in vivo cytometric imaging in mice (Proceedings of the National Academy of Sciences of the United States of America (2015) 112 (1350-1355) doi: 10.1073/pnas.1421632111) (2015) (0)
- Ly6C[superscript lo] monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy (2019) (0)
- 1463 Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression associated genes in locally advanced pancreatic cancer (2022) (0)
- IMST-40. REPROGRAMMING OF THE TUMOR IMMUNE MICROENVIRONMENT BY AN ANG-2/VEGF BISPECIFIC ANTIBODY DELAYS TUMOR GROWTH AND PROLONGS SURVIVAL IN PRECLINICAL GBM MODELS (2016) (0)
- Tumor Necrosis Factor «-induced Leukocyte Adhesion in Normal and Tumor Vessels: Effect of Tumor Type, Transplantation Site, and Host Strain1 (2006) (0)
- Primary tumor irradiation affects levels of systemic angiogenic agents: potential roles for both tumor and host tissues (2001) (0)
- erratum Perinuclear localizationof chromatin facilitates transcriptional silencing (0)
- Integrated Systems and Technologies Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing (2013) (0)
- Abstract A67: Reconditioning the tumor immune microenvironment for a breast cancer vaccine therapy. (2013) (0)
- Measurement of Gastric Blood Flow by Two Dimentional Laser Doppler Perfusion Imager (1993) (0)
- Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer (2019) (0)
- A9. Nitric oxide mediates tumor vessel maturation (2007) (0)
- In vivo determination of lymphocyte migration into follicles after sticking to postcapillary venules in rat peyer's patches (1994) (0)
- Consensus guidelines for the use and interpretation of angiogenesis assays (2018) (0)
- Proffered Paper: Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy (2016) (0)
- Abstract A12: Microenvironmental Interleukin-6 induced activation of STAT3 signaling in medulloblastoma: Implications for molecular pathology and therapy (2016) (0)
- BSCI-10. NEUROLOGICAL DYSFUNCTION CAUSED BY BRAIN TUMOR-GENERATED SOLID STRESS IS REVERSED BY LITHIUM (2019) (0)
- Metformin reduces ECM remodeling, EMT, and metastasis in a PDAC mouse model. (2015) (0)
- Side-View Endomicroscopy for High-Resolution In Vivo Imaging of the Gastrointestinal Tract (2012) (0)
- PLACENTAL GROWTH FACTOR/NEUROPILIN 1 SIGNALING IS A THERAPEUTIC TARGET IN PEDIATRIC MEDULLOBLASTOMA (2013) (0)
- Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies asin VivoTwo-Photon Oxygen Sensors The Harvard made this article openly available. Please share how this access benefits you. Your story matters (2016) (0)
- The Role of Stromal Cells in Tumor Metastases. (2009) (0)
- Retraction Note: A homing system targets therapeutic T cells to brain cancer (2019) (0)
- Abstract 3847: Metastasizing host stromal cells potentiate colonization of metastatic tumors (2010) (0)
- Inhibition of Phacoemulsification Probe???Induced Free Radicals by Hyaluronic Acid Viscous Material (1994) (0)
- 907 Blockade of VEGF, angiopoietin-2, and PD1 reprograms dysfunctional endothelial cells in glioblastoma to quasi-antigen-presenting cells (2022) (0)
- Abstract 90: Fatty acid synthesis is required for breast cancer brain metastasis (2021) (0)
- Creation of long‐lasting blood vessels in vivo (2008) (0)
- Abstract LB-267: Role of VEGFR-1 signaling in obesity-induced tumor progression (2015) (0)
- Compact high-quality CdS – CdS c re – shell nanocrystals with narrow emission lin widths and suppressed blinking SUPPLEMENTARY INFORMATION (2012) (0)
- Abstract IA5: The role of nitric oxide in the tumor microenvironment (2011) (0)
- Nitric oxide (NO) as a mediator of Kupffer cell-induced mitochondrial dysfunction in hepatocytes (1994) (0)
- TAMI-05. FATTY ACID SYNTHESIS IS REQUIRED FOR HER2+ BREAST CANCER BRAIN METASTASIS (2021) (0)
- BSCI-09. MECHANISMS OF ENHANCED DRUG DELIVERY IN BRAIN METASTASES WITH FOCUSED ULTRASOUND-INDUCED BLOOD-TUMOR BARRIER DISRUPTION (2019) (0)
- Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors (2015) (0)
- Effect of lipopolysaccharides on erythrocyte flow velocity in rat liver (1997) (0)
- Nitric oxide induces tumor cell cytotoxicity in rat liver microcirculatory units (1993) (0)
- S4-5 Noninvasive Imaging of Angiogenesis and Physiological Function in vivo (2002) (0)
- Abstract LB-288: Restoration of peri-vascular nitric oxide gradient radio-sensitizes murine breast cancers via vascular normalization. (2011) (0)
- Addition of losartan to FOLFIRINOX and chemoradiation reduces immunosuppression-associated genes, Tregs and FOXP3+ cancer cells in locally advanced pancreatic cancer. (2023) (0)
- Advances in Brief Irradiation of a Primary Tumor , Unlike Surgical Removal , Enhances Angiogenesis Suppression at a Distal Site : Potential Role of Host-Tumor Interaction 1 (2000) (0)
- Molecular and functional dissection of tumors by intravital microscopy (2004) (0)
- Abstracts of selected papers presented at the 34th annual meeting of the Japanese Society of Gastroenterology October 12–14, 1992, Utsunomiya, Japan (1993) (0)
- Wrapping and Tapping Anastomosis between Engrafted Endothelial Networks and Host Vasculature (2010) (0)
- Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice (2022) (0)
- 52. BrMPANEL: A PUBLIC RESOURCE OF ORGANOTROPIC CELL LINES (2020) (0)
- Advances in Brief Differential Transplantability of Tumor-Associated Stromal Cells (2004) (0)
- Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium (2019) (0)
- Abstract A48: Ado-trastuzumab emtansine (T-DM1) controls tumor progression of established HER2-positive breast cancer brain metastases in mice (2016) (0)
- Evaluation of anticancer agent transport in brain tumors after focused ultrasound-induced blood-brain/blood-tumor barrier disruption (2017) (0)
- Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as (2015) (0)
- Kupffer cell-induced tumor cell cytotoxicity - an involvement of nitric oxide (1993) (0)
- Abstract PO-097: Addition of losartan to FOLFIRINOX and chemoradiation reduces the expression of pro-invasive and immunosuppressive genes in locally-advanced pancreatic cancer (2021) (0)
- long-lasting functional vasculature derived mesenchymal stem cells facilitate engineering of − Bone marrow (2008) (0)
- wrapping-and-tapping anastomosis Engineered blood vessel networks connect to host vasculature via (2013) (0)
- Wrapping‐and‐tapping anastomosis connects implanted endothelial networks to host vasculature (2011) (0)
- Lazer Doppler perfusion imager: its principle and determination of tissue mirocirculation (1994) (0)
- Abstract IA17: Targeting placental growth factor/ neuropilin-1 pathway inhibits growth and spread of medulloblastoma (2014) (0)
- Balancing angiogenic pathways in solid tumors (2014) (0)
- 1241 IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer (2022) (0)
- Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model (2021) (0)
- Abstract P061: Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits the efficacy of immune checkpoint blockade (2022) (0)
- Phenotypic and functional characterization of proangiogenic monocytes (2008) (0)
- Irradiation of a primary tumor enhances inhibition of angiogenesis induced at a secondary site (1998) (0)
- F132. Leukocyte-endothelial interaction in tumors: Effects of TNFα, transplantation site and host (1995) (0)
- Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy (2023) (0)
- Neuropilin-1 (Nrp-1) as a prognostic biomarker and potential drug target for pediatric medulloblastoma. (2013) (0)
- Abstract 4195: Targeting the immune microenvironment to improve colorectal cancer anti-angiogenic therapy (2016) (0)
- IFNA pathway drives the more aggressive phenotype of KRASG12D-mutant pancreatic ductal adenocarcinomas via IFNAR1/STAT3 activation (2022) (0)
- DDRE-07. FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS (2021) (0)
- In vivo imaging of microvasculature using optical coherence tomography (2010) (0)
- Alimentary tract and pancreas. Bile acid-induced depolarization of mitochondrial membrane potential preceding cell injury in cultured gastric mucosal cells (1995) (0)
- Abstract 3925: Optical coherence tomography imaging in cancer research. (2013) (0)
- Dissecting tumor and vascular biology using multi-photon laser scanning microscopy (2006) (0)
- Abstract C57: The role of stromal cells in tumor metastases (2009) (0)
- A homing system targets therapeutic T cells to brain cancer (2018) (0)
- Restoring perivascular nitric oxide gradients normalizes breast cancer vasculature (2014) (0)
- Dissecting Tumor Biology Using Intravital Microscopy and Optical Frequency Domain Imaging (2013) (0)
- Tumor-host interaction modulates production of antiangiogenic factors from human pancreatic cancer (2001) (0)
- Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells (2022) (0)
- Optical methods in vascular biology and medicine. (2010) (0)
- Systemic levels of VEGF and endostatin are influenced by tumor, host, and treatment factors (2002) (0)
- In Vivo Fluorescence Cellular Imaging by Side-view Endomicroscopy (2010) (0)
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What Schools Are Affiliated With Dai Fukumura?
Dai Fukumura is affiliated with the following schools:
