Dale E. Bredesen

Dale E. Bredesen's AcademicInfluence.com Rankings

Dale E. Bredesen

Philosophy

#6228

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#9230

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#3411

World Rank

#4564

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Philosophy

Dale E. Bredesen's Degrees

Bachelors Chemistry California Institute of Technology

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Dale E. Bredesen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes (2009) (2078)
Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. (1993) (1724)
Bax directly induces release of cytochrome c from isolated mitochondria. (1998) (1579)
Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. (1985) (1127)
Coupling endoplasmic reticulum stress to the cell death program (2004) (1020)
An alternative, nonapoptotic form of programmed cell death. (2000) (877)
Anti-cancer activity of targeted pro-apoptotic peptides (1999) (872)
Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease (2010) (865)
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) (799)
Coupling Endoplasmic Reticulum Stress to the Cell Death Program (2001) (774)
Altered Reactivity of Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis (1996) (738)
Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis (1997) (725)
bcl-2 inhibits death of central neural cells induced by multiple agents. (1993) (629)
Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract* (1998) (608)
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia. (1999) (560)
Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78 (2002) (557)
Cell death in the nervous system (2006) (509)
Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates (1998) (493)
Coupling Endoplasmic Reticulum Stress to the Cell Death Program (2002) (459)
Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice. (2004) (459)
The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis (1998) (426)
Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. (1996) (402)
Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease (2002) (388)
Inhibiting Caspase Cleavage of Huntingtin Reduces Toxicity and Aggregate Formation in Neuronal and Nonneuronal Cells* (2000) (387)
Misfolded proteins, endoplasmic reticulum stress and neurodegeneration. (2004) (380)
A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor (2000) (375)
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. (1995) (349)
Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition. (1996) (301)
Targeting the prostate for destruction through a vascular address (2002) (298)
Netrin-1 controls colorectal tumorigenesis by regulating apoptosis (2004) (294)
Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix (2004) (291)
Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease (2004) (245)
The RET proto‐oncogene induces apoptosis: a novel mechanism for Hirschsprung disease (2000) (245)
Neural apoptosis (1995) (244)
Expression of bcl‐2 inhibits necrotic neural cell death (1995) (236)
Correction for Galvan et al., Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664 (2006) (224)
Shift of the Cellular Oxidation‐Reduction Potential in Neural Cells Expressing Bcl‐2 (1996) (217)
Absence of p75NTR Causes Increased Basal Forebrain Cholinergic Neuron Size, Choline Acetyltransferase Activity, and Target Innervation (1997) (217)
Human Bcl-2 Reverses Survival Defects in Yeast Lacking Superoxide Dismutase and Delays Death of Wild-Type Yeast (1997) (214)
The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation (2001) (211)
Kennedy's Disease (1999) (211)
Bcl‐2 Protects Isolated Plasma and Mitochondrial Membranes Against Lipid Peroxidation Induced by Hydrogen Peroxide and Amyloid β‐Peptide (1998) (197)
Sensory neuropathy with low‐dose pyridoxine (1985) (190)
Establishment of a Cell-Free System of Neuronal Apoptosis: Comparison of Premitochondrial, Mitochondrial, and Postmitochondrial Phases (1997) (187)
Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein. (1996) (186)
In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP. (2010) (184)
INVITED COMMENTARY IS APOPTOSIS MEDIATED BY REACTIVE OXYGEN SPECIES (1994) (180)
Central nervous system dysfunction in acquired immunodeficiency syndrome. (1988) (173)
p75NTR and apoptosis: Trk-dependent and Trk-independent effects (1997) (166)
A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor. (2000) (164)
AIDS And the Nervous System (1988) (162)
Molecular Components of a Cell Death Pathway Activated by Endoplasmic Reticulum Stress* (2004) (160)
Cerebral infarctions and transient neurologic deficits associated with acquired immunodeficiency syndrome. (1989) (154)
Activation of CPP32 during apoptosis of neurons and astrocytes (1997) (150)
Reversal of cognitive decline: A novel therapeutic program (2014) (143)
Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein (2010) (139)
bcl-2 expression decreases methyl mercury-induced free-radical generation and cell killing in a neural cell line. (1994) (137)
Neural-Targeted Gene Therapy for Rodent and Primate Hemiparkinsonism (1994) (136)
Ayurvedic medicinal plants for Alzheimer's disease: a review (2012) (134)
Bcl‐2 Protects Against Apoptosis in Neuronal Cell Line Caused by Thapsigargin‐Induced Depletion of Intracellular Calcium Stores (1998) (133)
Primary central nervous system lymphomas in patients with AIDS (1988) (132)
Bcl‐2 Protects Neural Cells from Cyanide/Aglycemia‐Induced Lipid Oxidation, Mitochondrial Injury, and Loss of Viability (1995) (130)
Deficits in Synaptic Transmission and Learning in Amyloid Precursor Protein (APP) Transgenic Mice Require C-Terminal Cleavage of APP (2006) (128)
Reversal of cognitive decline in Alzheimer's disease (2016) (125)
Determinants of Cytochrome c Pro-apoptotic Activity (2000) (122)
Effect of overexpression of BCL-2 on cellular oxidative damage, nitric oxide production, antioxidant defenses, and the proteasome. (2001) (121)
Cleavage of Atrophin-1 at Caspase Site Aspartic Acid 109 Modulates Cytotoxicity* (1999) (121)
Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature (2001) (121)
The dependence receptor hypothesis (2004) (114)
Activation of the cell stress kinase PKR in Alzheimer’s disease and human amyloid precursor protein transgenic mice (2003) (112)
The acquired immunodeficiency syndrome (AIDS) dementia complex. (1989) (112)
Direct Transcriptional Effects of Apolipoprotein E (2016) (111)
Caspase cleavage of the amyloid precursor protein modulates amyloid β‐protein toxicity (2003) (110)
Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain (2011) (110)
Apoptosis: overview and signal transduction pathways. (2000) (110)
Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue. (2001) (108)
Bcl-2 Expression in Neural Cells Blocks Activation of ICE/CED-3 Family Proteases during Apoptosis (1996) (107)
Expression of Myelin Protein Genes and Other Myelin Components in an Oligodendrocytic Cell Line Conditionally Immortalized with a Temperature‐Sensitive Retrovirus (1993) (107)
BCL-2 blocks glutamate toxicity in neural cell lines. (1993) (105)
Apoptosis and dependence receptors: a molecular basis for cellular addiction. (2004) (102)
Caspase cleavage of members of the amyloid precursor family of proteins (2002) (99)
Netrin-1 interacts with amyloid precursor protein and regulates amyloid-β production (2009) (97)
p75NTR and the concept of cellular dependence: seeing how the other half die (1998) (95)
Neuronal Apoptosis Induced by Pharmacological Concentrations of 3‐Hydroxykynurenine (2000) (94)
Measurement of cellular oxidation, reactive oxygen species, and antioxidant enzymes during apoptosis. (2000) (93)
Receptors that mediate cellular dependence (2005) (92)
Neurodegeneration in Alzheimer's disease: caspases and synaptic element interdependence (2009) (90)
Neuroprotective Sirtuin ratio reversed by ApoE4 (2013) (89)
Type 1 Insulin-like Growth Factor Receptor (IGF-IR) Signaling Inhibits Apoptosis Signal-regulating Kinase 1 (ASK1)* (2003) (89)
Amyloid β protein toxicity mediated by the formation of amyloid‐β protein precursor complexes (2003) (86)
Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR). (2003) (85)
Proteolytic Cleavage of Ataxin-7 by Caspase-7 Modulates Cellular Toxicity and Transcriptional Dysregulation* (2007) (84)
Coupling endoplasmic reticulum stress to the cell death program in mouse melanoma cells: effect of curcumin (2008) (82)
The Efficacy and Clinical Impact of Brain Imaging in Neurologically Symptomatic AIDS Patients: A Prospective CT/MRI Study (1990) (79)
Opportunistic central nervous system pathology in patients with AIDS (1988) (76)
Coupling endoplasmic reticulum stress to the cell-death program: a novel HSP90-independent role for the small chaperone protein p23 (2006) (74)
Improved prediction of critical residues for protein function based on network and phylogenetic analyses (2005) (74)
The Copper Transport Protein Atox1 Promotes Neuronal Survival* (2000) (74)
Is apoptosis mediated by reactive oxygen species? (1994) (73)
Atypical Recognition Consensus of CIN85/SETA/Ruk SH3 Domains Revealed by Target-assisted Iterative Screening* (2003) (71)
Signal transduction in Alzheimer disease: p21‐activated kinase signaling requires C‐terminal cleavage of APP at Asp664 (2008) (70)
Is p75NGFR involved in developmental neural cell death? (1994) (70)
Cellular resistance to methylmercury. (1996) (69)
The non‐existent aging program: how does it work? (2004) (68)
A ligand-receptor pair that triggers a non-apoptotic form of programmed cell death (2002) (67)
Increased intermediate M1-M2 macrophage polarization and improved cognition in mild cognitive impairment patients on ω-3 supplementation (2016) (66)
Contrasting Role of Presenilin-1 and Presenilin-2 in Neuronal Differentiation In Vitro (1999) (66)
Selective vulnerability in Alzheimer's disease: Amyloid precursor protein and p75NTR interaction (2009) (66)
A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease (2005) (65)
Alternative, Nonapoptotic Programmed Cell Death (2004) (65)
The safety and pharmacokinetics of GLQ223 in subjects with AIDS and AIDS-related complex: a phase I study. (1990) (64)
Molecular characterization of neurohybrid cell death induced by Alzheimer's amyloid‐β peptides via p75NTR/PLAIDD (2004) (61)
Science fact and the SENS agenda (2005) (61)
Endoplasmic reticulum stress-induced cell death mediated by the proteasome (2007) (61)
Dependence Receptors: From Basic Research to Drug Development (2011) (60)
Programmed cell death mechanisms in neurological disease. (2008) (59)
Identification of new modulators and protein alterations in non‐apoptotic programmed cell death (2010) (58)
ω‐3 Supplementation increases amyloid‐β phagocytosis and resolvin D1 in patients with minor cognitive impairment (2015) (58)
Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes. (2003) (57)
Interfering with multimerization of netrin-1 receptors triggers tumor cell death (2009) (57)
A Calpain-Like Protease Inhibits Autophagic Cell Death (2007) (55)
Metabolic profiling distinguishes three subtypes of Alzheimer's disease (2015) (55)
Neurogenesis in the adult brain: implications for Alzheimer's disease. (2007) (54)
Mechanism of cytotoxicity mediated by the C31 fragment of the amyloid precursor protein. (2009) (53)
Failure of naloxone to reverse Vascular neurologic deficits (1983) (53)
Coupling Endoplasmic Reticulum Stress to the Cell Death Program in Dopaminergic Cells: Effect of Paraquat (2008) (52)
The PDZ Domain as a Complex Adaptive System (2007) (49)
siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme. (2004) (48)
Prion protein gene expression in cultured cells. (1988) (48)
Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664 (2008) (48)
Dimerization‐dependent block of the proapoptotic effect of P75NTR (2000) (46)
C-terminal cleavage of the amyloid-beta protein precursor at Asp664: a switch associated with Alzheimer's disease. (2008) (46)
REVIEW ■ : Keeping Neurons Alive: The Molecular Control of Apoptosis (Part I (1996) (45)
Generation and analysis of normal and shiverer temperature-sensitive immortalized cell lines exhibiting phenotypic characteristics of oligodendrocytes at several stages of differentiation. (1993) (44)
Key Note Lecture: Toward a Mechanistic Taxonomy for Cell Death Programs (2007) (44)
Recovery of herpesviruses from cerebrospinal fluid of immunodeficient homosexual men (1985) (43)
Transcriptional Effects of ApoE4: Relevance to Alzheimer’s Disease (2018) (42)
De Novo-designed Peptide Transforms Golgi-specific Lipids into Golgi-like Nanotubules* (2001) (42)
Neuroprotective Herbs for the Management of Alzheimer’s Disease (2021) (41)
sAβPPα is a Potent Endogenous Inhibitor of BACE1. (2015) (41)
Enhancement of peroxynitrite-induced apoptosis in PC12 cells by fibroblast growth factor-1 and nerve growth factor requires p21Ras activation and is suppressed by Bcl-2. (1998) (39)
Novel Mediators of Amyloid Precursor Protein Signaling (2009) (38)
Tau phosphorylation in Alzheimer’s disease (2007) (36)
APAP, a sequence‐pattern recognition approach identifies substance P as a potential apoptotic peptide (2001) (35)
Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members (2011) (34)
Inhalational Alzheimer's disease: an unrecognized—and treatable—epidemic (2016) (33)
Do posttranslational modifications of CuZnSOD lead to sporadic amyotrophic lateral sclerosis? (1997) (32)
Science fact and the SENS agenda. What can we reasonably expect from ageing research? (2005) (31)
Downregulation of protein phosphatase 2A by apolipoprotein E: Implications for Alzheimer's disease (2017) (30)
Neural transplantation using temperaturesensitive immortalized neural cells: A preliminary report (1990) (30)
Efficient Identification of Critical Residues Based Only on Protein Structure by Network Analysis (2007) (30)
The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model (2014) (30)
Importance of the caspase cleavage site in amyloid-β protein precursor. (2010) (30)
Symmetrical cleavage of the metal-metal bond in decacarbonyldirhenium(0) by ultraviolet irradiation (1973) (30)
Periodic confusion caused by congenital extrahepatic portacaval shunt (1984) (29)
Neurosurgical implications of the acquired immunodeficiency syndrome (AIDS). (1988) (29)
No Consistent Bioenergetic Defects in Presynaptic Nerve Terminals Isolated from Mouse Models of Alzheimer's Disease (2012) (29)
Expression of bcl-2 inhibits cellular radical generation. (1996) (27)
Hunter-killer peptide (HKP) for targeted therapy. (2008) (27)
Next generation therapeutics for Alzheimer's disease (2013) (27)
Signaling via amyloid precursor-like proteins APLP1 and APLP2. (2011) (26)
Central nervous system disorders in AIDS. (1989) (26)
Do proteomics analyses provide insights into reduced oxidative stress in the brain of an Alzheimer disease transgenic mouse model with an M631L amyloid precursor protein substitution and thereby the importance of amyloid-beta-resident methionine 35 in Alzheimer disease pathogenesis? (2012) (25)
Differential regulation of the intrinsic pathway of apoptosis in brain and liver during ageing (2006) (25)
Reversal of Cognitive Decline: 100 Patients (2018) (25)
PLAIDD, a type II death domain protein that interacts with p75 neurotrophin receptor (2007) (24)
The neurology of human immunodeficiency virus infection. (1988) (23)
Endoplasmic Reticulum Stress–Induced Cell Death in Dopaminergic Cells: Effect of Resveratrol (2009) (23)
Paradoxical effect of TrkA inhibition in Alzheimer's disease models. (2014) (22)
Caspase 7 can cleave tumor necrosis factor receptor-I (p60) at a non-consensus motif, in vitro. (2001) (22)
Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: A role for early experience (2010) (21)
A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer’s disease mouse model (2018) (21)
Interaction of ASK1 and the β-amyloid precursor protein in a stress-signaling complex (2007) (21)
Neurological reactions in HIV‐infected patients treated with trichosanthin (1993) (21)
Cell death mechanisms in ALS (1996) (20)
Neural transplantation of cells expressing the anti-apoptotic gene bcl-2. (1995) (20)
Mining DNA microarray data using a novel approach based on graph theory (2001) (19)
An Artificially Designed Pore-forming Protein with Anti-tumor Effects* (2003) (19)
Moonlighting Peptides with Emerging Function (2012) (19)
Neoplasms of the anterior pituitary. (1978) (18)
Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease. (2016) (16)
Expression of CD40 induces neural apoptosis (1997) (16)
Valosin-Containing Protein Gene Mutations: Cellular Phenotypes Relevant to Neurodegeneration (2011) (16)
AβPP-selective BACE inhibitors (ASBI): novel class of therapeutic agents for alzheimer's disease. (2013) (16)
Target-Assisted Iterative Screening Reveals Novel Interactors for PSD95, Nedd4, Src, Abl and Crk proteins (2002) (16)
Neurotrophin dependence domain (2000) (15)
The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline (2017) (15)
An unconventional IAP‐binding motif revealed by target‐assisted iterative screening (TAIS) of the BIR3‐cIAP1 domain (2007) (14)
Alzheimer’s Model Develops Early ADHD Syndrome (2016) (14)
Genetic control of neural cell apoptosis. (1996) (13)
Hot Topics in Research: Preventive Neuroradiology in Brain Aging and Cognitive Decline (2015) (13)
Altering APP Proteolysis: Increasing sAPPalpha Production by Targeting Dimerization of the APP Ectodomain (2012) (13)
Neurologic complications of HIV infection. (1990) (12)
REVIEW ■ : Keeping Neurons Alive: The Molecular Control of Apoptosis (Part II (1996) (11)
Phosphorylation of the common neurotrophin receptor p75 by p38β2 kinase affects NF-κB and AP-1 activities (2000) (11)
A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation (1997) (11)
Structural and functional alterations in amyloid-β precursor protein induced by amyloid-β peptides. (2011) (11)
A Novel Motif Identified in Dependence Receptors (2007) (10)
Photochemistry of aquo- and hydroxopentacyanocobaltate(III) (1973) (10)
A second cytotoxic proteolytic peptide derived from β-amyloid precursor protein (2000) (10)
Beyond Apoptosis: Cellular Outcomes of Cancer Therapy (2008) (9)
Dynamic self-guiding analysis of Alzheimer's disease (2015) (9)
Target-assisted iterative screening of phage surface display cDNA libraries. (2004) (9)
Phosphorylation of the common neurotrophin receptor p75 by p38beta2 kinase affects NF-kappaB and AP-1 activities. (2000) (9)
Rebuttal to Austad: ‘Is aging programmed? (2004) (8)
Toward a mechanistic taxonomy of cell death programs. (2005) (8)
The Small Chaperone Protein p23 and Its Cleaved Product p19 in Cellular Stress (2012) (8)
Meeting Report: Cellular Dependence--Old Concept, New Mechanisms (2003) (8)
Apoptotic cell death of a temperature-sensitive central neuronal cell line (1995) (8)
Ayurvedic Profiling of Alzheimer's Disease. (2017) (7)
Alzheimer’s disease as a systems network disorder: chronic stress/dyshomeostasis, innate immunity, and genetics (2020) (7)
Controversies in HIV-related central nervous system disease: neuropsychological aspects of HIV-1 infection. (1989) (7)
Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project (2022) (7)
Hunter—Killer Peptide (HKP) for Targeted Therapy (2009) (7)
ReCODE: A Personalized, Targeted, Multi-Factorial Therapeutic Program for Reversal of Cognitive Decline (2021) (6)
Precision Medicine Approach to Alzheimer's Disease: Successful Proof-of-Concept Trial (2021) (5)
Neural Transplantation of Cells Expressing the Anti-Apoptotic Gene Bcl-2 (1995) (5)
[Dependence receptors: links between apoptosis, nervous system development and control of tumorigenesis]. (2000) (5)
Increasing the proliferative capacity of muscular dystrophy myoblasts (1992) (4)
Loss of oxidation-reduction specificity in amyotrophic lateral sclerosis-associated CuZnSOD mutants (2000) (4)
Prionic Loops , Anti-Prions , and Dependence Receptors in Neurodegeneration (2013) (4)
Endogenously EGFP-Labeled Mouse Embryonic Stem Cells. (2011) (4)
APP-based neuroprotective strategies. (2007) (3)
Intracellular Calcium Stores and Ischemic Neuronal Death (1996) (3)
Developmental shift in the apostat: Comparison of neurones and astrocytes (2005) (3)
apoptosis by a mechanism requiring receptor proteolysis (1998) (3)
Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. 1985. (2007) (3)
The small co-chaperone p23 overexpressing transgenic mouse (2013) (3)
Screening for Small Molecule Inhibitors of Statin-Induced APP C-terminal Toxic Fragment Production (2017) (2)
Differential Regulation of Smac/DIABLO and Hsp-70 during Brain Maturation (2007) (2)
Preliminary characterization of long-term reaggregating cultures of trisomy 16 central nervous system. (1992) (2)
Case Study: A Precision Medicine Approach to Multifactorial Dementia and Alzheimer's Disease. (2021) (2)
The APP ligand Netrin-1 improves memory and biomarkers after ICV administration in PD APP mice (2012) (2)
Do Posttranslational Modifications of CuZnSOD Lead to Lateral Sporadic Amyotrophic (1997) (2)
Toward a Mechanistic Taxonomy for Programmed Cell Death Pathways (2008) (2)
NOVEL TRANSCRIPTIONAL ROLE OF APOE4 (2016) (2)
Induction of the C-terminal proteolytic cleavage of AβPP by statins. (2011) (2)
Human Slow Infections Caused by Prions (1989) (2)
Comprar Beyond Apoptosis: Cellular Outcomes of Cancer Therapy | Igor B. Roninson | 9780849391927 | Informa Healthcare (2007) (2)
Cell death programs in neural development and disease (2002) (1)
Erratum: siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme (Biochemical and Biophysical Research Communications (2004) 314 (283-291) DOI: 10.1016/j.bbrc.2003.12.098) (2004) (1)
Apoptosis: Role of Programmed Cell Death in Neurodegenerative Disease (2011) (1)
Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease (2011) (1)
Neurodegenerative Disease and Cancer: Two Sides of a Coin? (2001) (1)
Ayurvedic medicinal plants for Alzheimer's disease: a review (2012) (1)
BACE, APP Processing, and Signal Transduction in Alzheimer's Disease (2010) (1)
Novel prionic and anti-prionic mechanisms in Alzheimer's disease (2011) (1)
Rationale for a Multi-Factorial Approach for the Reversal of Cognitive Decline in Alzheimer’s Disease and MCI: A Review (2023) (1)
Deactivation of biacetyl triplets by cyanocobaltate(III) complexes (1972) (1)
Differential Expression and Redox Proteomics Analyses of an Alzheimer Disease Transgenic Mouse Model: Effects of the Amyloid-β Peptide of APPΞ (2011) (1)
POSSIBLE ANTIOXIDANT ACTION OF THE Bcl-2 PROTEIN (1996) (1)
mCiRNA—Synaptic Crystal Ball? (2012) (1)
Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease (2011) (1)
Response of Solid Tumors to Cancer Therapy: How Relevant Is Apoptosis? (2008) (0)
Swimming training-to-criterion and pre-exposure to MWM are required for complete restoration of learning in APP transgenic mice carrying a mutation in Asp664 (2009) (0)
Erratum: Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664 (Proceedings of the National Academy of Sciences of the United States of America (2006) 103, (7130-7135)) (2007) (0)
NEURONALLY-DERIVED EXOSOMAL PROTEINS CAN PREDICT BRAIN AMYLOIDOSIS (2016) (0)
Neurology: neurologic manifestations of AIDS. (1985) (0)
Preventing C31 generation does not prevent many Aβ-dependenent neuronal and behavioral impairments in the happ-J20 mouse model of Alzheimer's disease (2009) (0)
A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer’s disease mouse model (2018) (0)
Exercise Is a No-Brainer for Brain Health , Reducing Dementia and Depression , and Preventing Memory Loss May (2018) (0)
Transcriptional Effects of ApoE4: Relevance to Alzheimer’s Disease (2017) (0)
Release of c-terminal truncated and intact tau from Alzheimer's disease cortical synapses (2015) (0)
The ret proto‐oncogene induces apoptosis: Proapoptotic activity and hirschsprung disease (1999) (0)
NORMALIZATION OF HIPPOCAMPAL SIRTUIN 1 LEVELS IN A MURINE APOLIPOPROTEIN E4-5XFAD MODEL OF AD RESTORES COGNITIVE FUNCTION (2018) (0)
Correction: Moonlighting Peptides with Emerging Function (2013) (0)
Novel Synthetic Hunter-Killer Peptides Target and Destroy Prostate Cancer (2002) (0)
AMYLOID PRECURSOR PROTEIN C-TERMINAL CLEAVAGE RESULTING IN THE TOXIC C31 PEPTIDE: STIMULATION OF CLEAVAGE WITH CEREVASTATIN AND INHIBITION AND CELL VIABILITY RESCUE USING SMALL MOLECULES (2016) (0)
Correction: Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members (2012) (0)
Bcl-2 Protection of Mitochondrial Function Following Chemical Hypoxia/Aglycemia (1996) (0)
Neurobiology of Disease Direct Transcriptional Effects of Apolipoprotein E (2016) (0)
THE PARADOX OF REACTIVE OXYGEN SPECIES, APOPTOSIS, AND BCL-2 (1996) (0)
mutation of Asp664 Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by (2006) (0)
A DICHOTOMY OF PROTECTION BY BCL-2 FROM MITOCHONDRIAL POISONS (1996) (0)
Cell death mechanisms in ALS. Discussion (1996) (0)
Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism? (2023) (0)
Targeting trka inhibition in Alzheimer's disease therapy (2015) (0)
Cellular addiction receptors and their relationship to Alzheimer's disease (2000) (0)
Neuropathy after pyridoxine or toxic contaminants (1986) (0)
Modes of Cell Death by Anticancer Agents: The Crucial Importance of Dose (2008) (0)
IDENTIFICATION OF AN EXPERIMENTAL DRUG THAT ENHANCES BRAIN SIRTUIN 1 LEVELS AND IMPROVES COGNITION AS A POTENTIAL NEW THERAPEUTIC FOR AD (2019) (0)
8 – Programmed Cell Death and Its Role in Neurological Disease (2007) (0)
The Small Chaperone Protein p23 and Its Cleaved Product p19 in Cellular Stress (2011) (0)
Emerging relationship between development and degeneration: TrkA-APP interaction as a therapeutic target in Alzheimer's disease (2012) (0)
NEURONALLY-DERIVED EXOSOMAL PROTEINS CAN PREDICT BRAIN AMYLOIDOSIS (2016) (0)
Novel downstream mediators of APP signalling (2009) (0)
Which Way Did They Go? Neural Cell Death Pathways (2003) (0)
Increasing sAPPα levels by targeting dimerization of the APP ectodomain (2012) (0)
Moonlighting peptides with an emerging function by design [Erratum] (2013) (0)
Aβ-Induced Toxicity Mediated by Caspase Cleavage of the Amyloid Precursor Protein (APP) (2008) (0)
AIDS and the Central Nervous System: A Challenge for the New Neuropsychiatry (1989) (0)
Modulation of Cell Death in Neural Cell Lines and Transplants (1995) (0)
Viewpoint (0)
Correction to hunter-killer peptide (HKP) for targeted therapy. (2015) (0)
O4-05-03 A key role of the C-terminal cleavage of APP in Alzheimer’s disease (2006) (0)
Modulation of the intracellular proteolytic cleavage of APP by statins (2011) (0)
Development of ApoE4-Targeted Drug Candidates for Alzheimer’s Disease (2016) (0)
The dependence receptor DCC defines a new mechanism for caspase activation (1999) (0)
CHAPTER 13 – Genetic Control of Neural Apoptosis (1995) (0)
Cleavage of actin by interleukin 1(3-converting (2005) (0)
Alzheimer’s Disease, the Microbiome, and 21st Century Medicine (2019) (0)
Neurologic Disease in the Acquired Immunodeficiency Syndrome (2020) (0)
Cellular effects of APOE4: Implications for Alzheimer's disease (2011) (0)

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What Schools Are Affiliated With Dale E. Bredesen?

Dale E. Bredesen is affiliated with the following schools:

George Washington University
University of California, Los Angeles
University of California, San Francisco
University of Vienna