Dale L. Greiner

Q: What Schools Are Affiliated With Dale L. Greiner

Dale L. Greiner is affiliated with the following schools: Allegheny University of the Health Sciences, University of Massachusetts Medical School, University of Connecticut, University of Massachusetts

Dale L. Greiner's AcademicInfluence.com Rankings

Dale L. Greiner

Biology

#8908

World Rank

#12049

Historical Rank

Immunology

#521

World Rank

#538

Historical Rank

biology Degrees

Download Badge

Biology

Dale L. Greiner's Degrees

Bachelors Biology University of Massachusetts Amherst

Similar Degrees You Can Earn

Best Online Bachelor's in Biology 2026

Why Is Dale L. Greiner Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Dale L. Greiner's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Human Lymphoid and Myeloid Cell Development in NOD/LtSz-scid IL2Rγnull Mice Engrafted with Mobilized Human Hemopoietic Stem Cells 12 (2004) (1568)
Generation of Functional Human Pancreatic β Cells In Vitro (2014) (1520)
Humanized mice in translational biomedical research (2007) (1284)
Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice. (1995) (1261)
Humanized mice for immune system investigation: progress, promise and challenges (2012) (816)
Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates (2015) (586)
Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome. (2012) (563)
T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice (2008) (467)
Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. (1995) (447)
Long term Glycemic Control Using Polymer Encapsulated, Human Stem-Cell Derived β-cells in Immune Competent mice (2016) (441)
Humanized Mouse Models of Clinical Disease. (2017) (383)
Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates (2016) (346)
SCID Mouse Models of Human Stem Cell Engraftment (1998) (335)
Major Histocompatibility Complex Class I-Deficient NOD-B2mnull Mice are Diabetes and Insulitis Resistant (1994) (319)
Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. (1998) (311)
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia (2014) (307)
Human peripheral blood leucocyte non‐obese diabetic‐severe combined immunodeficiency interleukin‐2 receptor gamma chain gene mouse model of xenogeneic graft‐versus‐host‐like disease and the role of host major histocompatibility complex (2009) (295)
Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice. (1997) (256)
Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats (1987) (251)
Treatment of Allograft Recipients with Donor-Specific Transfusion and Anti-CD154 Antibody Leads to Deletion of Alloreactive CD8+ T Cells and Prolonged Graft Survival in a CTLA4-Dependent Manner1 (2000) (248)
Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets (2015) (247)
Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation. (2010) (245)
Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines (2015) (232)
Rat models of type 1 diabetes: genetics, environment, and autoimmunity. (2004) (216)
Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors (1986) (206)
High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice. (1995) (205)
Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy (2017) (203)
Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques (2018) (194)
Absence of the RT-6 T cell subset in diabetes-prone BB/W rats. (1986) (193)
Non‐obese diabetic–recombination activating gene‐1 (NOD–Rag 1 null) interleukin (IL)‐2 receptor common gamma chain (IL 2 rγnull) null mice: a radioresistant model for human lymphohaematopoietic engraftment (2008) (185)
The role of JNK in the development of hepatocellular carcinoma. (2011) (184)
Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. (1997) (180)
Creation of “Humanized” Mice to Study Human Immunity (2008) (179)
Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/Lt mice. (2000) (176)
β2 Microglobulin-deficient (B2mnull) NOD/SCID mice are excellent recipients for studying human stem cell function (2000) (175)
Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency. (1997) (175)
CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment. (1999) (174)
Colony Stimulating Factor-1 Receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates (2017) (171)
Humanized mouse models to study human diseases (2010) (170)
Improved engraftment of human spleen cells in NOD/LtSz-scid/scid mice as compared with C.B-17-scid/scid mice. (1995) (169)
A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. (2008) (164)
Tuberculosis susceptibility of diabetic mice. (2007) (163)
NOD/LtSz-Rag1null Mice: An Immunodeficient and Radioresistant Model for Engraftment of Human Hematolymphoid Cells, HIV Infection, and Adoptive Transfer of NOD Mouse Diabetogenic T Cells1 (2000) (161)
Virus-Induced Abrogation of Transplantation Tolerance Induced by Donor-Specific Transfusion and Anti-CD154 Antibody (2000) (158)
Human cancer growth and therapy in immunodeficient mouse models. (2014) (158)
Direct Visualization of Cross-Reactive Effector and Memory Allo-Specific CD8 T Cells Generated in Response to Viral Infections1 (2003) (144)
Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection (2015) (144)
TLR Agonists Abrogate Costimulation Blockade-Induced Prolongation of Skin Allografts1 (2006) (139)
TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats1 (2005) (138)
GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation (2013) (136)
c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells. (2014) (127)
Induction of immunologic tolerance for transplantation. (1999) (127)
Generation of improved humanized mouse models for human infectious diseases (2014) (125)
Extensive double humanization of both liver and hematopoiesis in FRGN mice (2014) (123)
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes (2018) (123)
Inhibition of Bromodomain Proteins for the Treatment of Human Diffuse Large B-cell Lymphoma (2014) (123)
Cardioprotection with postconditioning: loss of efficacy in murine models of type-2 and type-1 diabetes. (2011) (121)
GABA Promotes Human β-Cell Proliferation and Modulates Glucose Homeostasis (2014) (121)
A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells (2015) (120)
Dengue Virus Infection and Virus-Specific HLA-A2 Restricted Immune Responses in Humanized NOD-scid IL2rγnull Mice (2009) (119)
Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease. (1999) (119)
Humanized nonobese diabetic-scid IL2rγnull mice are susceptible to lethal Salmonella Typhi infection (2010) (119)
NOD mice have a generalized defect in their response to transplantation tolerance induction. (1999) (118)
Overcoming current limitations in humanized mouse research. (2013) (114)
Humanized SCID mouse models for biomedical research. (2008) (114)
Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats. (1996) (112)
Improved engraftment of human cord blood stem cells in NOD/LtSz-scid/scid mice after irradiation or multiple-day injections into unirradiated recipients. (1996) (105)
Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice. (1996) (104)
Targeted Delivery of Small Interfering RNA to Human Dendritic Cells To Suppress Dengue Virus Infection and Associated Proinflammatory Cytokine Production (2009) (104)
The immunodeficient scid mouse as a model for human lymphatic filariasis (1991) (103)
In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery (2016) (103)
TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant Rat1 (2007) (103)
Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. (2011) (102)
Ian4 is required for mitochondrial integrity and T cell survival (2003) (100)
Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats. (1990) (99)
Regulated splicing of the α6 integrin cytoplasmic domain determines the fate of breast cancer stem cells. (2014) (98)
Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. (2017) (97)
Prevention of Diabetes in BB/Wor Rat by Single Transfusion of Spleen Cells: Parameters That Affect Degree of Protection (1989) (96)
Enhanced humoral and HLA‐A2‐restricted dengue virus‐specific T‐cell responses in humanized BLT NSG mice (2012) (95)
Early Growth Response Gene-2, a Zinc-Finger Transcription Factor, Is Required for Full Induction of Clonal Anergy in CD4+ T Cells1 (2004) (94)
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate (2012) (92)
Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning. (2003) (90)
beta2 microglobulin-deficient (B2m(null)) NOD/SCID mice are excellent recipients for studying human stem cell function. (2000) (88)
Translating data from animal models into methods for preventing human autoimmune diabetes mellitus: caveat emptor and primum non nocere. (2001) (85)
Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. (2005) (85)
Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF. (2012) (83)
Skin Allograft Maintenance in a New Synchimeric Model System of Tolerance1 2 (2001) (83)
Infections That Induce Autoimmune Diabetes in BBDR Rats Modulate CD4+CD25+ T Cell Populations12 (2003) (82)
Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor. (1995) (80)
Growth and reproduction complex in the rat. Genes linked to the major histocompatibility complex that affect development (1980) (78)
Lack of acute xenogeneic graft‐versus‐host disease, but retention of T‐cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression (2018) (77)
Neutrophil Responses to Sterile Implant Materials (2015) (76)
Type 1 IFN Mediates Cross-Talk between Innate and Adaptive Immunity That Abrogates Transplantation Tolerance12 (2007) (75)
Genetic Disassociation of Autoimmunity and Resistance to Costimulation Blockade-Induced Transplantation Tolerance in Nonobese Diabetic Mice1 (2003) (75)
Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo (2012) (73)
NOD-scid IL2r&ggr;null Mouse Model of Human Skin Transplantation and Allograft Rejection (2010) (73)
Altered Expression of Diabetes in BB/Wor Rats by Exposure to Viral Pathogens (1991) (72)
The BB/Wor rat and the balance hypothesis of autoimmunity. (1996) (71)
Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras. (2013) (71)
Long-Term Implant Fibrosis Prevention in Rodents and Non-Human Primates Using Localized Deliverable Crystals (2019) (71)
Stress-impaired transcription factor expression and insulin secretion in transplanted human islets. (2016) (70)
Correction: Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice (2016) (70)
Humanized mice as a preclinical tool for infectious disease and biomedical research (2011) (69)
NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment (2003) (68)
High frequency apoptosis of recent thymic emigrants in the liver of lymphopenic diabetes-prone BioBreeding rats. (1998) (67)
Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors. (2015) (67)
Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis. (2015) (67)
Multiple Low-Dose Streptozocin–induced Diabetes in NOD-scid/scid Mice in the Absence of Functional Lymphocytes (1994) (66)
Rapid Recruitment and Activation of Macrophages by Anti-Gal/α-Gal Liposome Interaction Accelerates Wound Healing (2011) (66)
Regulation of Human Cell Engraftment and Development of EBV-Related Lymphoproliferative Disorders in Hu-PBL-scid Mice1 (2000) (65)
Prevention of diabetes in the BB rat by essential fatty acid deficiency. Relationship between physiological and biochemical changes (1990) (65)
Humanized Mouse Models for Transplant Immunology (2016) (64)
AATF mediates anti-apoptotic effect of the unfolded protein response through transcriptional regulation of AKT1 (2009) (64)
Human Immune System Development and Rejection of Human Islet Allografts in Spontaneously Diabetic NOD-Rag1null IL2rγnull Ins2Akita Mice (2010) (64)
Humanized NOD/LtSz‐scid IL2 Receptor Common Gamma Chain Knockout Mice in Diabetes Research (2007) (64)
Abnormalities in the export and fate of recent thymic emigrants in diabetes-prone BB/W rats. (1996) (63)
Long-term survival of skin allografts induced by donor splenocytes and anti-CD 154 antibody in thymectomized mice requires CD 4 ( + ) T cells , interferon-gamma , and CTLA 4 (1998) (62)
Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells. (2003) (62)
Adoptive transfer of autoimmune diabetes mellitus to athymic rats: synergy of CD4+ and CD8+ T cells and prevention by RT6+ T cells. (1994) (62)
End Sequence Analysis Toolkit (ESAT) expands the extractable information from single-cell RNA-seq data (2016) (62)
Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice (2012) (61)
Humanized mice for the study of infectious diseases. (2013) (61)
A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours (2016) (60)
Emv30null NOD-scid Mice: An Improved Host for Adoptive Transfer of Autoimmune Diabetes and Growth of Human Lymphohematopoietic Cells (1995) (59)
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice (2019) (59)
GLI1 regulates a novel neuropilin-2/alpha6beta1 integrin based autocrine pathway that contributes to breast cancer initiation (2014) (58)
NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction. (2003) (58)
Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects. (1988) (58)
Human BLyS Facilitates Engraftment of Human PBL Derived B Cells in Immunodeficient Mice (2008) (57)
Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat. (1999) (57)
Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4. (1999) (56)
Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency (2017) (56)
Humanized mouse models of immunological diseases and precision medicine (2019) (55)
Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells. (2018) (54)
CHOP Mediates Endoplasmic Reticulum Stress-Induced Apoptosis in Gimap5-Deficient T Cells (2009) (54)
LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation. (2005) (53)
Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids. (2011) (53)
Induction of immunological tolerance to islet allografts. (1996) (52)
Islet cell transplantation tolerance. (2001) (52)
Characterization of monoclonal antibodies that define rat T cell alloantigens. (1983) (51)
Cell-Extrinsic MHC Class I Molecule Engagement Augments Human NK Cell Education Programmed by Cell-Intrinsic MHC Class I. (2016) (51)
A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells (2020) (51)
Defective lymphopoiesis in bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. I. Analysis of development of prothymocytes, early B lineage cells, and terminal deoxynucleotidyl transferase-positive cells (1986) (51)
Blockade of the Programmed Death-1 (PD1) Pathway Undermines Potent Genetic Protection from Type 1 Diabetes (2014) (50)
Dietary Cow's Milk Protein Does Not Alter the Frequency of Diabetes in the BB Rat (1997) (50)
Spleen cell transfusion in the Bio-Breeding/Worcester rat. Prevention of diabetes, major histocompatibility complex restriction, and long-term persistence of transfused cells. (1986) (50)
IMP3 promotes stem-like properties in triple-negative breast cancer by regulating SLUG (2016) (49)
Ectonucleoside Triphosphate Diphosphohydrolase-3 Antibody Targets Adult Human Pancreatic β Cells for In Vitro and In Vivo Analysis. (2019) (49)
Prolonged Survival of Rat Islet and Skin Xenografts in Mice Treated with Donor Splenocytes and Anti-CD154 Monoclonal Antibody (1998) (48)
Thymic expression of insulin‐related genes in an animal model of autoimmune type 1 diabetes (2001) (48)
Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice (2016) (48)
Humanized Mice for the Study of Type 1 Diabetes and Beta Cell Function (2008) (48)
Blockade of CD40-Mediated Signaling Is Sufficient for Inducing Islet But Not Skin Transplantation Tolerance 1 (2003) (47)
Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. (2013) (47)
A Novel Alloantigen-Specific CD8+PD1+ Regulatory T Cell Induced by ICOS-B7h Blockade In Vivo1 (2007) (47)
Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers (2011) (46)
CD28 and ITK signals regulate autoreactive T cell trafficking (2013) (45)
Characterization of RT6 bearing rat lymphocytes. I. Ontogeny of the RT6+ subset. (1988) (45)
Maturation-Dependent Licensing of Naive T Cells for Rapid TNF Production (2010) (45)
Expanded CD34+ Human Umbilical Cord Blood Cells Generate Multiple Lymphohematopoietic Lineages in NOD-scid IL2rγ null Mice (2008) (45)
A new isolation method for rat intraepithelial lymphocytes (1999) (44)
P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer. (2016) (44)
NOD/LtSz-Rag1 Mice: An Immunodeficient and Radioresistant Model for Engraftment of Human Hematolymphoid Cells, HIV Infection, and Adoptive Transfer of NOD Mouse Diabetogenic T Cells (2000) (43)
A Regulatory CD4+ T Cell Subset in the BB Rat Model of Autoimmune Diabetes Expresses Neither CD25 Nor Foxp31 (2006) (42)
Viral Infection of Engrafted Human Islets Leads to Diabetes (2014) (42)
Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity. (1996) (42)
Viral infection abrogates CD8(+) T-cell deletion induced by costimulation blockade. (2000) (42)
Viral abrogation of stem cell transplantation tolerance causes graft rejection and host death by different mechanisms. (2002) (42)
Development of novel major histocompatibility complex class I and class II-deficient NOD-SCID IL2R gamma chain knockout mice for modeling human xenogeneic graft-versus-host disease. (2010) (41)
Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics (2015) (41)
Infection With Viruses From Several Families Triggers Autoimmune Diabetes in LEW.1WR1 Rats (2009) (40)
Regulation of Skin and Islet Allograft Survival in Mice Treated With Costimulation Blockade is Mediated by Different CD4+ Cell Subsets and Different Mechanisms (2004) (40)
Prolonged skin allograft survival in mice treated with Flt3-ligand-induced dendritic cells and anti-CD154 monoclonal antibody. (1999) (40)
Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. II. Description of a microenvironmental defect for the generation of terminal deoxynucleotidyltransferase-positive bone marrow cells in vitro. (1987) (40)
Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats (1991) (39)
Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells (2020) (39)
Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats (2011) (39)
Diabetes prone BB rats are severely deficient in natural killer T cells. (1999) (38)
Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice. (2004) (38)
Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice (2015) (37)
Rapid quantification of naive alloreactive T cells by TNF-alpha production and correlation with allograft rejection in mice. (2007) (37)
DR-BB Rat Thymus Contains Thymocyte Populations Predisposed to Autoreactivity (1995) (36)
Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice (2013) (36)
Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice (2013) (36)
Thymic epithelial defects and predisposition to autoimmune disease in BB rats. (1994) (36)
Deficiencies in Gut NK Cell Number and Function Precede Diabetes Onset in BB Rats1 (2004) (35)
Prevention of “Humanized” Diabetogenic CD8 T-Cell Responses in HLA-Transgenic NOD Mice by a Multipeptide Coupled-Cell Approach (2011) (35)
Prevention of Type 1 Diabetes in the Rat With an Allele-Specific Anti–T-Cell Receptor Antibody (2012) (34)
Allografts Stimulate Cross‐Reactive Virus‐Specific Memory CD8 T Cells with Private Specificity (2008) (34)
NOD-scidIl2rgtm1Wjl and NOD-Rag1nullIl2rgtm1Wjl: A Model for Stromal Cell–Tumor Cell Interaction for Human Colon Cancer (2014) (34)
Identification of thymocyte progenitors in hemopoietic tissues of the rat. II. Enrichment of functional prothymocytes on the fluorescence- activated cell sorter (1982) (34)
Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. (2012) (33)
Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable. (2020) (33)
The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. (2005) (33)
The iddm4 locus segregates with diabetes susceptibility in congenic WF.iddm4 rats. (2002) (32)
Role of RT6+ T lymphocytes in mercury-induced renal autoimmunity: experimental manipulations of "susceptible" and "resistant" rats. (1994) (32)
Characterization of RT6-Bearing Rat Lymphocytes. II. Developmental Relationships of RT6- and RT6+T Cells (1991) (32)
Improved skin allograft tolerance induced by treatment with donor splenocytes and an extended course of anti-CD154 monoclonal antibody. (1998) (32)
Nicotinamide Adenine Dinucleotide (NAD) and Its Metabolites Inhibit T Lymphocyte Proliferation: Role of Cell Surface NAD Glycohydrolase and Pyrophosphatase Activities1 (2001) (31)
Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout. (1997) (31)
Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus (2009) (31)
Intrinsic Cytotoxicity of Natural Killer Cells to Pancreatic Islets In Vitro (1990) (31)
Role of Host Immune System in BB/Wor Rat: Predisposition to Diabetes Resides in Bone Marrow (1988) (31)
Humanized mice for the study of type 1 and type 2 diabetes (2011) (30)
Genome-wide Analysis of Salmonellaenterica serovar Typhi in Humanized Mice Reveals Key Virulence Features. (2019) (30)
Protein kinase C signaling during T cell activation induces the endoplasmic reticulum stress response (2008) (30)
Oral Insulin Does Not Prevent Insulin‐dependent Diabetes Melltus in BB Rats (1996) (29)
Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy (2020) (29)
Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody. (1999) (28)
Variables to predict engraftment of umbilical cord blood into immunodeficient mice: usefulness of the non‐obese diabetic–severe combined immunodeficient assay (2001) (28)
RAT XENOGRAFT SURVIVAL IN MICE TREATED WITH DONOR-SPECIFIC TRANSFUSION AND ANTI-CD154 ANTIBODY IS ENHANCED BY ELIMINATION OF HOST CD4+ CELLS1 (2001) (28)
Regulated splicing of the alpha6 integrin cytoplasmic domain determines the fate of breast cancer stem cells (2019) (28)
Are Diabetes and Insulitis Resistant (1994) (28)
An RT6a Gene Is Transcribed and Translated in Lymphopenic Diabetes-Prone BB Rats (1993) (28)
Identification of thymocyte progenitors in hemopoietic tissues of the rat. I. A quantitative assay system for thymocyte regeneration. (1984) (27)
Thymus atrophy and changes in thymocyte subpopulations of BN rats with mercury-induced renal autoimmune disease. (1996) (27)
Influence of gonadal steroids on susceptibility to Brugia malayi in scid mice. (1994) (27)
Different Mechanisms Control Peripheral and Central Tolerance in Hematopoietic Chimeric Mice (2007) (27)
Costimulation and Autoimmune Diabetes in BB Rats (2006) (27)
Partial versus Full Allogeneic Hemopoietic Chimerization Is a Preferential Means to Inhibit Type 1 Diabetes as the Latter Induces Generalized Immunosuppression1 (2006) (27)
Characterization of Mouse Rt6.1 NAD:Arginine ADP-ribosyltransferase* (1997) (27)
Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells. (2016) (27)
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics (2017) (26)
An Atypical Population of NK Cells That Spontaneously Secrete IFN-γ and IL-4 Is Present in the Intraepithelial Lymphoid Compartment of the Rat1 2 (2001) (26)
The pathogenesis of autoimmune diabetes mellitus. (1990) (26)
Reduction of the RT6.2+ subset of T lymphocytes in brown Norway rats with mercury-induced renal autoimmunity. (1991) (26)
Islet Cell Autoimmunity and Transplantation Tolerance: Two Distinct Mechanisms? (2003) (25)
ART2, a T Cell Surface Mono-ADP-ribosyltransferase, Generates Extracellular Poly(ADP-ribose)* (2006) (25)
Biochemical Studies of RT6 Alloantigens in BB/Wor and Normal Rats: Evidence for Intact Unexpressed RT6a Structural Gene in Diabetes-Prone BB Rats (1990) (24)
A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function (2008) (24)
CD8+ T lymphocytes are not required for murine resistance to human filarial parasites. (1992) (24)
Subcapsular transplantation of tissue in the kidney. (2014) (24)
Insulin dependent diabetes mellitus hypothesis of autoimmunity. (1991) (24)
Defects in the thymic epithelial stroma of diabetes prone BB rats. (1989) (24)
T-cell activation and transplantation tolerance. (2012) (24)
Induction of Immunological Tolerance to Islet Allografts (1996) (23)
Effect of ex vivo cytokine treatment on human cord blood engraftment in NOD‐scid mice (2000) (23)
Islet allograft survival induced by costimulation blockade in NOD mice is controlled by allelic variants of Idd3. (2004) (23)
A Novel Role for the Centrosomal Protein, Pericentrin, in Regulation of Insulin Secretory Vesicle Docking in Mouse Pancreatic β-cells (2010) (22)
The RT6 (Art2) family of ADP-ribosyltransferases in rat and mouse (2004) (22)
Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the rat. (1996) (22)
Hyperglycemia-Induced Proliferation of Adult Human Beta Cells Engrafted Into Spontaneously Diabetic Immunodeficient NOD-Rag1null IL2r&ggr;null Ins2Akita Mice (2011) (22)
PROLONGED SURVIVAL OF NEONATAL PORCINE ISLET XENOGRAFTS IN MICE TREATED WITH A DONOR-SPECIFIC TRANSFUSION AND ANTI-CD154 ANTIBODY1 (2004) (22)
Autoimmune Destruction of Islets Transplanted Into RT6-Depleted Diabetes-Resistant BB/Wor Rats (1990) (22)
mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell–derived hematopoietic progenitors (2017) (22)
Dengue virus infection and virus‐specific immune responses in humanized NOD‐scid IL2rgammanull mice (2008) (22)
CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. (1994) (21)
Effects of irradiation on diabetes in the BB/Wor rat. (1989) (21)
Haptoglobin as an early serum biomarker of virus-induced autoimmune type 1 diabetes in biobreeding diabetes resistant and LEW1.WR1 rats (2010) (21)
Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγnull mice treated with alogliptin (2013) (21)
Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue (2017) (21)
Depletion of the programmed death-1 receptor completely reverses established clonal anergy in CD4(+) T lymphocytes via an interleukin-2-dependent mechanism. (2009) (21)
In vivo correction of anaemia in beta-thalassemic mice by gammaPNA-mediated gene editing with nanoparticle delivery (2019) (20)
Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat (2005) (20)
Mercury-induced renal autoimmunity in BN-->LEW.1N chimeric rats. (1994) (20)
Generation of β cell‐specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen‐transgenic mice (2015) (20)
Recapitulation of normal and abnormal BioBreeding rat T cell development in adult thymus organ culture. (1999) (20)
Developmental abnormalities of terminal deoxynucleotidyl transferase positive bone marrow cells and thymocytes in New Zealand mice: effects of prostaglandin E1. (1985) (20)
The Rat T-Cell Surface Protein RT6 Is Associated With src Family Tyrosine Kinases and Generates an Activation Signal (1996) (20)
T cell lines derived from the spinal cords of mice with experimental allergic encephalomyelitis are self reactive. (1986) (20)
Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice. (2005) (20)
Closing the Circle between the Bedside and the Bench (2008) (19)
Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic β‐cell function via glycogen synthase kinase‐3β (2016) (19)
Refinement of the Iddm4 Diabetes Susceptibility Locus Reveals TCRVβ4 as a Candidate Gene (2007) (18)
Induce Allograft Tolerance with Combined CTLA 4 Signals Are Required to Optimally (1999) (18)
Defective lymphopoiesis in the bone marrow of motheaten (me/me) and viable motheaten (mev/mev) mutant mice. III. Normal mouse bone marrow cells enable mev/mev prothymocytes to generate thymocytes after intravenous transfer (1987) (18)
A novel hemolytic complement-sufficient NSG mouse model supports studies of complement-mediated antitumor activity in vivo. (2017) (18)
The T cell marker RT6 in a rat model of autoimmune diabetes. (1997) (18)
Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. (2011) (18)
Characterization of rat prothymocyte with monoclonal antibodies recognizing rat lymphocyte membrane antigenic determinants. (1987) (17)
Mercury-induced renal autoimmunity: changes in RT6+ T-lymphocytes of susceptible and resistant rats. (1993) (17)
Distinct Differences on Neointima Formation in Immunodeficient and Humanized Mice after Carotid or Femoral Arterial Injury (2016) (17)
Virus-Induced Autoimmune Diabetes in the LEW.1WR1 Rat Requires Iddm14 and a Genetic Locus Proximal to the Major Histocompatibility Complex (2009) (17)
Ectopic high endothelial venules in pancreatic ductal adenocarcinoma: A unique site for targeted delivery (2018) (17)
Tolerance to islet xenografts induced by dual manipulation of antigen presentation and co-stimulation. (1996) (17)
Levels of Art2+ Cells but not Soluble Art2 Protein Correlate with Expression of Autoimmune Diabetes in the BB Rat (2001) (16)
Maturation of functional T-lymphocyte subpopulations in the rat. (1982) (16)
Development of New‐Generation HU‐PBMC‐NOD/SCID Mice to Study Human Islet Alloreactivity (2007) (15)
Imaging the pancreatic vasculature in diabetes models (2011) (15)
Mercury-induced autoimmunity in Brown Norway rats: kinetics of changes in RT6+ T lymphocytes correlated with IgG isotypes of circulating autoantibodies to laminin 1. (1998) (15)
The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice (2015) (15)
TLR Agonists Prevent the Establishment of Allogeneic Hematopoietic Chimerism in Mice Treated with Costimulation Blockade12 (2009) (15)
T-Lymphocyte Requirement for Diabetes in RT6-Depleted Diabetes-Resistant BB rats (1991) (15)
alpha Cell Function and Gene Expression Are Compromised in Type 1 Diabetes (2019) (15)
Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet‐induced obesity and insulin resistance (2016) (14)
Relative susceptibility of SJL/J and B10.S mice to experimental allergic encephalomyelitis (EAE) is determined by the ability of prethymic cells in bone marrow to develop into EAE effector T cells (1993) (14)
Blockade of CD40-CD154 interferes with human T cell engraftment in scid mice. (1998) (14)
A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion (2021) (14)
Corrigendum: Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates (2016) (14)
Costimulatory Blockade Induces Hyporesponsiveness in T Cells that Recognize Alloantigen via Indirect Antigen Presentation (2006) (14)
Recapitulation of normal and abnormal BB rat immune system development in scid mouse/rat lymphohemopoietic chimeras. (1991) (14)
B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. (1995) (14)
Humanized Mice in Translational Immunology (2016) (14)
Alloimmune Injury and Rejection of Human Skin Grafts on Human Peripheral Blood Lymphocyte–Reconstituted Non-Obese Diabetic Severe Combined Immunodeficient β2-Microglobulin-Null Mice (2003) (14)
Monoclonal antibodies to RT7 and LCA antigens in the rat: cell distribution and segregation analysis. (1987) (13)
A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic‐related cytokine release syndrome (2020) (13)
Induction of tolerance for islet transplantation for type 1 diabetes (2003) (13)
Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation (2016) (13)
The RT6 rat lymphocyte alloantigen circulates in soluble form. (1993) (13)
Evaluation of Donor-Specific Transfusion Sources: Unique Failure of Bone Marrow Cells to Induce Prolonged Skin Allograft Survival with Anti-CD154 Monoclonal Antibody (2004) (12)
Thymic Involution in Viable Motheaten (meυ) Mice is Associated with a Loss of Intrathymic Precursor Activity (1992) (12)
Viral Infection: A Potent Barrier to Transplantation Tolerance (2008) (12)
Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice (2009) (12)
High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors. (1993) (11)
Reproductive endocrine profile of a strain of rats which exhibits aspermatogenesis and reduced growth. (1980) (11)
Effects of HgCl2 on the expression of autoimmune responses and disease in diabetes-prone (DP) BB rats. (1997) (11)
Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity. (2007) (11)
GENETIC LINKAGE AND CELL DISTRIBUTION ANALYSIS OF T CELL ALLOANTIGENS IN THE RAT (1982) (11)
Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats. (1994) (11)
Salicylate Prevents Virus-Induced Type 1 Diabetes in the BBDR Rat (2013) (11)
35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
Investigations of T-lymphocyte subpopulations in the rat using alloantigenic markers. (1979) (10)
Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD–scid IL-2rgnull RIP-DTR mice engrafted with human islets (2015) (10)
Viral Abrogation of Stem Cell Transplantation Tolerance Causes Graft Rejection and Host Death by Different Mechanisms1 (2002) (10)
Role of innate immunity in transplantation tolerance. (2008) (10)
Intravital dye-labeled diabetogenic rat T cells retain dye, home to the pancreas, and induce diabetes. (1999) (10)
The RT6 (Art2) family of ADP-ribosyltransferases in rat and mouse. (1999) (10)
T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7. (2002) (10)
Experimental autoallergic sialadenitis in the LEW rat. I. Parameters of disease induction. (1991) (9)
Induction of insulin-dependent diabetes mellitus in PVG.RT1u rats. (1997) (9)
Possible type 1 diabetes risk prediction: Using ultrasound imaging to assess pancreas inflammation in the inducible autoimmune diabetes BBDR model (2017) (9)
Survival of Onchocerca volvulus in nodules implanted in immunodeficient rodents. (1992) (9)
Experimental autoallergic sialadenitis in the LEW rat. III. Role of CD4+ T cells in EAS induction. (1991) (8)
Humanized mouse models for immuno-oncology research (2023) (8)
Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities. (1987) (8)
Genetically modified human CD4+ T cells can be evaluated in vivo without lethal graft‐versus‐host disease (2016) (8)
Modeling human T1D-associated autoimmune processes (2021) (8)
A selective culture system for generating terminal deoxynucleotidyl transferase-positive lymphoid precursor cells in vitro. IV. Properties and developmental relationships of the lymphoid cells in the adherent and nonadherent compartments of the culture. (1994) (8)
Whole-cell ( + )-ambrein production in the yeast Pichia pastoris (2003) (8)
Diethylcarbamazine (DEC) does not induce nitric oxide (NO) synthesis. (1998) (7)
BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes. (2001) (7)
End Sequence Analysis ToolKit ( ESAT ) expands the extractable from single cell RNA-seq experiments (2016) (7)
Dapagliflozin does not directly affect human α or β cells. (2020) (7)
Preparation of (111)In-DTPA morpholino oligomer for low abdominal accumulation. (2010) (7)
A Feasible Approach to Evaluate the Relative Reactivity of NHS-Ester Activated Group with Primary Amine-Derivatized DNA Analogue and Non-Derivatized Impurity (2015) (7)
Genetic Separation of the Transplantation Tolerance and Autoimmune Phenotypes in NOD Mice (2003) (7)
TLR Agonists Abrogate Co‐stimulation Blockade‐Induced Mixed Chimerism and Transplantation Tolerance (2008) (7)
Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6 (2003) (7)
Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody. (2012) (7)
Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (7)
Unexpected side products in the conjugation of an amine-derivatized morpholino oligomer with p-isothiocyanate benzyl DTPA and their removal. (2011) (7)
Failure of alpha-galactosylceramide to prevent diabetes in virus-inducible models of type 1 diabetes in the rat. (2009) (6)
Recovery of viable endocrine‐specific cells and transcriptomes from human pancreatic islet‐engrafted mice (2019) (6)
Characterization of high density lipoprotein-bound and soluble RT6 released following administration of anti-RT6.1 monoclonal antibody. (1998) (6)
Proteomic and Transcriptional Profiles of Human Stem Cell-Derived β Cells Following Enteroviral Challenge (2020) (6)
The iddm 4 Locus Segregates With Diabetes Susceptibility in Congenic WF . iddm 4 Rats (2002) (6)
Abstract 1905: Restoration of Normoglycemia Re-Establishes the Infarct-Sparing Effect of Postconditioning in Diabetic Mice (2008) (6)
Alloreactive CD8 T cells rescued from apoptosis during co‐stimulation blockade by Toll‐like receptor stimulation remain susceptible to Fas‐induced cell death (2013) (5)
Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice (2014) (5)
Sufficient for Inducing Islet But Not Skin Blockade of CD 40-Mediated Signaling Is (2003) (5)
Type 1 cytokines polarize thymocytes during T cell development in adult thymus organ cultures☆ (2003) (5)
A quantitative assay system for thymocyte regeneration in the rat. (1981) (5)
Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice (2021) (5)
Determinants of memory in experimental filarial infections in mice (2007) (5)
Rat Stem-Cell Factor Induces Splenocytes Capable Of Regenerating The Thymus (1992) (5)
Lack of graft-versus-host-like pathology in mercury-induced autoimmunity of Brown Norway rats (2003) (5)
Quantitative Correlation of in Vivo Properties with in Vitro Assay Results: The in Vitro Binding of a Biotin-DNA Analogue Modifier with Streptavidin Predicts the in Vivo Avidin-Induced Clearability of the Analogue-Modified Antibody. (2015) (5)
Enhanced development of functional human NK cells in NOD‐ scid‐IL2rgnull mice expressing human IL15 (2022) (5)
Regulatory T cell control of autoimmune destruction of beta cells in the BB rat. (1988) (4)
Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture. (2001) (4)
Maternal influence on susceptibility of offspring to Brugia malayi infection in a murine model of filariasis. (1994) (4)
Mouse RT6 locus 1 and rat RT6.2 are NAD+. Arginine ADP-ribosyltransferases with auto-ADP-ribosylation activity. (1997) (4)
RFX6-mediated dysregulation defines human β cell dysfunction in early type 2 diabetes (2021) (4)
Patient-Derived Xenografts (PDX) of B Cell Lymphoma in NSG Mice: A Mouse Avatar for Developing Personalized Medicine (2015) (4)
Human Anti–HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1 (2018) (4)
Animal models for immunodeficiency diseases. (1992) (4)
Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death. (2021) (4)
Blockade of Cd40-Cd154 Interferes with Human T cell Engraftment in Scid Mice (1998) (4)
Monoclonal antibody analysis of Listeria monocytogenes-induced cytotoxic lymphocytes. (1986) (4)
A Regulatory CD 4 T Cell Subset in the BB Rat Model of Autoimmune Diabetes Expresses Neither CD 25 Nor Foxp 31 (2006) (4)
Thymic insulin-like growth factors (IGFs) in man and in an animal model of autoimmune IDDM (1996) (4)
Anti‐mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice (2006) (3)
Islet cells but not thyrocytes are susceptible to lysis by NK cells. (1991) (3)
HIV-1 infectivity of human T cells in a human/murine chimeric fetal thymic organ culture system. (1996) (3)
Evidence for elevated prothymocyte activity in the bone marrow of New Zealand Black (NZB) mice. Elevated prothymocyte activity in NZB mice. (1992) (3)
Regulated splicing of the alpha 6 integrin cytoplasmic domain determines the fate of breast cancer stem cells (2014) (3)
Cellular basis of the genetic susceptibility of murine experimental allergic encephalomyelitis (1986) (2)
Localization of prothymocytes from wild-type and viable motheaten mice following intravenous injection into irradiated adoptive recipients. (1994) (2)
Personal view INSULIN DEPENDENT DIABETES MELLITUS HYPOTHESIS OF AUTOIMMUNITY (1991) (2)
Development of humanized mouse models to study human immune system-tumor interactions (TUM10P.1055) (2015) (2)
Antileukemic Activity of Shepherdin, a Novel Targeted Inhibitor of the Survivin-Hsp90 Complex. (2005) (2)
Mechanisms of allograft prolongation in RT6 T cell-depleted rats. (1991) (2)
NSG™-Quad mice, a new humanized mouse model with improved human innate immune cell development (2016) (2)
Transgenic expression of human IL15 in NOD-scid IL2rg null (NSG) mice enhances the development and survival of functional human NK cells (2018) (2)
A novel transgenic mouse model of lysosomal storage disorder. (2016) (2)
Experimental autoallergic sialadenitis in the LEW rat. II. Target antigens are associated with cell surface and intracellular particulate fractions derived from the submandibular gland. (1991) (2)
Diabetes Research in Jeopardy (2007) (2)
Rat immunoglobulin genes have comparable patterns of JH rearrangement in normal peripheral B cells and in pre-B and cultured TdT+ cells from bone marrow. (1988) (2)
Abstract 4782: Epigenetic resistance to Notch inhibition in T cell acute lymphoblastic leukemia (2014) (1)
Abstract 5674: Transgenic expression of human IL15 in NOD-scid IL2rgnull(NSG) mice enhances the development and survival of functional human NK cells (2018) (1)
Growth of the human filarial parasite Brugia malayi in mice lacking major histocompatibility complex class II antigen expression. (1996) (1)
Abstract 5676: Patient-derived tumor xenografts in humanized NSG-SGM3 mice: An improved immuno-oncology platform (2018) (1)
Role of RT6{sup +} T lymphocytes in mercury-induced renal autoimmunity: Experimental manipulations of {open_quotes}susceptible{close_quotes} and {open_quotes}resistant{close_quotes} rats (1994) (1)
Abstract 5665: NOD-scid IL2rgnull(NSG) mice deficient in murine MHC Class I and Class II expression support engraftment of functional human T cells in the absence of acute xenogeneic GVHD following injection of PBMC (2018) (1)
Analysis of human immune responses to human allografts in small animal models. (1999) (1)
Enhanced development of functional human innate immune cells in a novel mouse FLT3null NSG mouse strain expressing human FLT3L (2020) (1)
Characterization and use of human insulin transgenic mouse models for type 1 diabetes (2020) (1)
Analysis of the Iddm14 Rat Diabetes Susceptibility Locus in Multiple Rat Strains: Identification of a Susceptibility Haplotype in the Tcrb-V13 Gene and Prevention of Diabetes by Depletion of Vbeta13+ T Cells (2010) (1)
Humanized mouse models of immunological diseases and precision medicine (2019) (1)
Thymic insulin-related polypeptides in diabetes-prone Bio-Breeding rats (1999) (1)
Phenotypic heterogeneity of Gross virus-induced thymic lymphomas in the rat: cellular origins and migratory properties. (1985) (1)
Depletion of RT6+ T lymphocytes prolongs skin allograft in rats. (1989) (1)
Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach. (2014) (1)
Prostaglandin E2 stimulates cAMP signaling and re-sensitizes human leukemia cells to glucocorticoid-induced cell death. (2020) (1)
Expresses Neither CD25 Nor Foxp3 Rat Model of Autoimmune Diabetes A Regulatory CD4+ T Cell Subset in the BB (2013) (0)
The Iddm14 gene is Tcrbv-13S1A1: Prevention of Autoimmune Diabetes in the Rat with an Allele-Specific Depleting Antibody That Recognizes the Vβ13a T Cell Receptor Beta Chain (2012) (0)
Required for Full Induction of Clonal Anergy Zinc-Finger Transcription Factor , Is Early Growth Response Gene-2 , a (2004) (0)
Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice (2013) (0)
Synchimeric Model System of Tolerance Skin Allograft Maintenance in a New (2013) (0)
Abstract 2049: A novel, rapid, sensitive, and reproducible in vivo platform to assess efficacy and toxicity of bispecific antibodies (2022) (0)
2 INTRATHYMIC TRANSFER ASSAY FOR THYMOCYTE PRECURSORS poietic (2003) (0)
TREATMENT WITH POLYINOSINIC:POLYCYTIDYLIC ACID (POLY I:C) PREVENTS THE DELETION OF CD8+T CELLS BY COSTIMULATION BLOCKADE INVOLVED IN THE INDUCTION OF ALLOGRAFT TOLERANCE.: Abstract# 718 (2000) (0)
Discovery and Development of Human Monoclonal Antibodies to Block RhD Alloimmunization During Pregnancy (2016) (0)
B10.S mice have both cellular and environmental resistance to EAE induction (1987) (0)
P-Rex 1 Promotes Resistan ce to VEGF / VEGFR-Targeted Therapy in Prostate Cancer Graphical (2016) (0)
A donor-dependent in vivo model for single agent and drug combination cytokine release syndrome safety evaluation. (2019) (0)
I-Ag7 β56/57 polymorphisms regulate non-cognate negative selection to CD4+ T cell orchestrators of type 1 diabetes (2023) (0)
Humanized Mice for the Generation of HIV-1 Human Monoclonal Antibodies (2016) (0)
An Early Islet Transcriptional Signature is Associated with Local Inflammation in Autoimmune Diabetes. (2022) (0)
EXTRA-UTERINE DIFFERENTIATION OF EMBRYONIC ALLOGRAFTS INTO MATURE TISSUES IN IMMUNOCOMPETENT MICE TREATED WITH ANTI-CD154 ANTIBODY AND A DONOR SPECIFIC TRANSFUSION (1999) (0)
The ImmunodeficientscidMouse asa Model for Human LymphaticFilariasis (1991) (0)
Human skin allograft rejection in a small animal model (2000) (0)
RatsVirus Infection to Induce Diabetes in BBDR TLR Activation Synergizes with Kilham Rat (2004) (0)
Differential regulation of alloreactive CD8 T cell responses by inflammation. (IRC8P.440) (2015) (0)
A novel anti-CD40 antibody prevents activation of alloreactive T cells and prolongs skin allograft survival (2016) (0)
OR.51. A Critical Role for the Innate Immune Response in Virus-Induced Autoimmune Diabetes (2006) (0)
Novel Human Colon Cancer Explant Model to Interrogate Tumor Stromal Interaction (2011) (0)
A novel role for the centrosome protein, pericentrin, in regulation of insulin granule docking (2010) (0)
Thymic insulin-related polypeptides: role in T cell selection and in central self-tolerance of the insulin family (1999) (0)
Dapagliflozin Treatment Impacts ß, but Not a, Cell Function in Normal Human Islets (2018) (0)
T Cell + CD25+ in BBDR Rats Modulate CD4 Infections That Induce Autoimmune Diabetes (0)
A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells (2020) (0)
Generation de chimerisme hematopoietique et induction de tolerance centrale (2004) (0)
Diabetic Mice Blockade-Induced Transplantation Tolerance Resistance to Costimulation Genetic Disassociation of Autoimmunity and (2003) (0)
Role of inflammation in preventing the induction of transplantation tolerance (TRAN1P.876) (2014) (0)
Abstract 1640: Enhanced development of functional human innate immune cells in a novel FLT3nullNSG mouse strain expressing human FLT3L (2022) (0)
Imaging human pancreatic islet cells in mice by MORF/cMORF pretargeting (2010) (0)
Abstract 5632: PBMC-humanized mouse model for the assessment of cytokine release syndrome caused by checkpoint and bispecific immunotherapy (2020) (0)
- 1001 End Sequence Analysis Toolkit ( ESAT ) expands the extractable information from single-cell RNA-seq data (2019) (0)
Cells in Acute Graft Versus Host Disease T Cells Requires CD154 Expression by Th + Cutting Edge: Sustained Expansion of CD8 (1999) (0)
Abstract B72: Humanized NSG-Tg(Hu-IL15) mice support preclinical immune-oncology efficacy for testing of NK cell-based immunotherapy (2020) (0)
I-Prevention and Treatment of DKA INV 1 Treatment of diabetic ketoacidosis in children : New perspectives on intravenous fluid protocols and risk of cerebral injury (2017) (0)
Monoclonal Antibody Treatment Donor-Specific Transfusion and Anti-CD154 Induce Allograft Tolerance with Combined CTLA4 Signals Are Required to Optimally (1999) (0)
NOD-scid IL2rg null (NSG) mice deficient in murine MHC Class I and Class II expression support engraftment of functional human T cells in the absence of acute xenogeneic GVHD following injection of PBMC (2018) (0)
Immunotherapy of the BB Rat * (2019) (0)
CD28-ITK signals regulate autoreactive T cell trafficking into tissues (123.41) (2012) (0)
Clathrin light chain‐conjugated drug delivery for cancer (2021) (0)
a CTLA 4-Dependent Manner T Cells and Prolonged Graft Survival + CD 8 Antibody Leads to Deletion of Alloreactive Donor-Specific Transfusion and Anti-CD 154 Treatment of Allograft Recipients with (1999) (0)
Abstract 1522: NovelNOD-scid IL2rgnull(NSG)mice for preclinical evaluation of TLR agonists in cancer immunotherapy (2019) (0)
Thymic insulin-related genes: role in T-lymphocyte development and self-tolerance of the insulin family (2000) (0)
Development of a humanized mouse model for functional testing of biomaterial fibrosis (2019) (0)
Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques (2018) (0)
Mice scid Lymphoproliferative Disorders in Hu-PBL-Development of EBV-Related Regulation of Human Cell Engraftment and and (2000) (0)
Generalized Immunosuppression Inhibit Type 1 Diabetes as the Latter Induces Chimerization Is a Preferential Means to Partial versus Full Allogeneic Hemopoietic (2006) (0)
Abstract 3902: Increased sensitivity for detecting cytokine release syndrome with cancer immunotherapy using a PBMC humanized NSG-SGM3 mouse model (2019) (0)
Diabetes-Resistant Rat Diabetes in the Biobreeding Kilham Rat Virus-Induced Autoimmune TLR 9-Signaling Pathways Are Involved in Greiner (2006) (0)
Comparison between Y-90 and Tc-99m labeled effectors in pretargeted mice by a co-injection approach and the conventional group approach (2013) (0)
Abstract 1070: Evaluation of human NK cell responses to PDX tumors in humanized NOD-scid IL2rgnull(NSG) mice expressing human IL15 (2019) (0)
Recapitulation ofNormalandAbnormalBB RatImmuneSystemDevelopment inscidMouse/RatLymphohemopoietic Chimeras (1991) (0)
Patient-derived AML mouse models with FLT3-ITD and IDH1 mutations (2016) (0)
Pretargeting vs direct targeting of a human islet cell transplant in mice (2011) (0)
Abrogates Transplantation Tolerance Innate and Adaptive Immunity That Type 1 IFN Mediates Cross-Talk between (2007) (0)
Competitive Repopulation Assay for Human Stem Cell Engraftment in NOD- scid IL-2rγ nul Mice. (2005) (0)
Mice scid Effectors into NSG versus NOD-Polyclonal Nonobese Diabetic (NOD) T Cell Transfer of Autoimmune Diabetes by Regulatory T Cells Diminish Adoptive The Presence and Preferential Activation of (2015) (0)
Licensing of naïve T cells for rapid TNF production (138.14) (2010) (0)
9th germinal centre conference bone marrow, B-cell differentiation and the B-cell system (1988) (0)
HIV Infection , and Adoptive Transfer for Engraftment of Human Hematolymphoid Immunodeficient and Radioresistant Model Mice : An nullRag 1 NOD / (2000) (0)
255-OR: ADA Presidents’ Select Abstract: Glucagon Receptor Antagonism Stimulates Beta-Cell Proliferation in Mouse and Human Islets (2020) (0)
Modulation de l'apoptose (2004) (0)
Development of a humanized mouse model that recapitulates the fibrotic response to biomaterial implants (2017) (0)
705. Selective Advantage of Hepatocytes Expressing Wild-Type Alpha-1 Antitrypsin (AAT) in a Novel Human Liver Xenograft Model: A Model for Correction of a Gain-Of-Function Mutation (2015) (0)
Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model. (2022) (0)
Monoclonal Antibody Treatment Transfusion and Anti-CD154 with Combined Donor-Specific Optimally Induce Allograft Tolerance CTLA4 Signals Are Required to (2010) (0)
Allografts stimulate cross‐reactive virus‐specific memory CD8 T cells with private specificity (2008) (0)
3-6-2018 α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes (2018) (0)
Diabetes-Prone BioBreeding Rats Emigrants in the Liver of Lymphopenic High Frequency Apoptosis of Recent Thymic (1998) (0)
Abstract 2875: Development of a new tumor-bearing humanized mouse model to evaluate the efficacy and toxicity of bispecific T cell engagers (2022) (0)
Author Correction: Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates (2021) (0)
Temporary inaccessibility for avidin to a biotinylated antibody in mice (2014) (0)
The role of the thymus in T cell self-tolerance of neuroendocrine principles and in development of neuroendocrine autoimmunity (1997) (0)
P19-56 LB. Priming with SOCS-1 silenced Dendritic cells induces robust HIV-specific CTL response in a novel HLA-A2 transgenic humanized mouse model (2009) (0)
Blockade In Vivo Regulatory T Cell Induced by ICOS-B 7 h + PD 1 + A Novel Alloantigen-Specific CD 8 Sayegh and (2007) (0)
autoimmunity in islet-allografted NOD / Lt mice disease , induction of skin allograft tolerance , and prevention of recurrent myeloablation and anti-CD 154 antibody : absence of graft-versus-host Allogeneic hematopoietic chimerism in mice treated with sublethal (2000) (0)
Human natural killer cell education is dynamically controlled by environmental and cell-intrinsic HLA (2016) (0)
CD169(+) macrophages mediate retrovirus trans-infection of permissive lymphocytes to establish infection in vivo (2016) (0)
Abstract 4990: An in vivo method for determining cancer immunotherapy induced cytokine release syndrome utilizing PBMC humanized mice (2019) (0)
NOD-scid IL2rγnull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity. (2023) (0)
Su.16. The Iddm4 Rat Diabetes Susceptibility Locus: Tcrvβ4 As a Candidate Gene (2006) (0)
Interaction Accelerates Wound Healing -Gal Liposome α Macrophages by Anti-Gal/ Rapid Recruitment and Activation of (2017) (0)
Proceedings of the Frontiers of Retrovirology Conference 2016 (2016) (0)
DEFECTIVE LYMPHOPOIESIS IN BONE MARROW OF MOTHEATEN (2003) (0)
Infections Cells Generated in Response to Viral Effector and Memory Allo-Specific CD 8 T Direct Visualization of Cross-Reactive (2003) (0)
Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue (2017) (0)
Inhibition of Bromodomain Proteins in Treatment of Diffuse Large B-cell Lymphoma (2014) (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Dale L. Greiner?

Dale L. Greiner is affiliated with the following schools:

Dale L. Greiner's Academic­Influence.com Rankings