Dan Littman

Q: What Schools Are Affiliated With Dan Littman

Dan Littman is affiliated with the following schools: Washington University in St. Louis, Weizmann Institute of Science, University of Oxford, University of British Columbia, Princeton University, Stanford University, University of California, San Francisco, Columbia University, New York University, University of Zurich

Dan Littman's AcademicInfluence.com Rankings

Dan Littman

Biology

#2107

World Rank

#3385

Historical Rank

#964

USA Rank

Immunology

#69

World Rank

#75

Historical Rank

#23

USA Rank

biology Degrees

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Biology

Dan Littman's Degrees

Doctorate Medicine University of California, San Francisco
PhD Immunology University of California, San Francisco

Why Is Dan Littman Influential?

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According to Wikipedia, Dan R. Littman is an American immunologist best known for his work on T lymphocytes. He is Professor of Molecular Immunology at New York University, an investigator of the Howard Hughes Medical Institute, and a member of the National Academy of Sciences. On October 15, 2012, he was elected as a member of the Institute of Medicine. He became a co-editor of the Annual Review of Immunology in 2013.

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Dan Littman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Identification of a major co-receptor for primary isolates of HIV-1 (1996) (3874)
Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria (2009) (3830)
Blood monocytes consist of two principal subsets with distinct migratory properties. (2003) (3434)
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells (2006) (3309)
Interactions Between the Microbiota and the Immune System (2012) (3264)
ATP mediates rapid microglial response to local brain injury in vivo (2005) (3238)
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development (1998) (2565)
DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells (2000) (2542)
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. (2006) (2263)
Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion (2000) (2226)
Signal transduction by lymphocyte antigen receptors (1994) (2190)
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways (2007) (1988)
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. (2002) (1881)
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor (2013) (1784)
CX3CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance (2005) (1591)
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. (2008) (1581)
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function (2008) (1518)
Plasticity of CD4+ T cell lineage differentiation. (2009) (1515)
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. (2010) (1414)
Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis (2013) (1394)
Control of microglial neurotoxicity by the fractalkine receptor (2006) (1378)
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development (2006) (1271)
The microbiota in adaptive immune homeostasis and disease (2016) (1162)
A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells (2006) (1084)
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E (2003) (1034)
A Validated Regulatory Network for Th17 Cell Specification (2012) (991)
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt (2008) (981)
An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells (2004) (952)
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation (2010) (944)
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes (2000) (904)
A new classification for HIV-1 (1998) (899)
Sparse and Compositionally Robust Inference of Microbial Ecological Networks (2014) (861)
Requirement for RORgamma in thymocyte survival and lymphoid organ development. (2000) (780)
Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development (2002) (763)
Expression cloning of new receptors used by simian and human immunodeficiency viruses (1997) (737)
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring (2016) (733)
Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22 (2009) (729)
Identification of IL-17-producing FOXP3+ regulatory T cells in humans (2009) (697)
In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression (1997) (692)
A Coordinated Change in Chemokine Responsiveness Guides Plasma Cell Movements (2001) (675)
Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype (1997) (665)
The microbiome in infectious disease and inflammation. (2012) (647)
Interaction of the unique N-terminal region of tyrosine kinase p56 lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs (1990) (634)
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family (1985) (626)
Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids (2005) (621)
Innate lymphoid cells drive IL-23 dependent innate intestinal pathology (2010) (577)
DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration (2011) (566)
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells (2012) (563)
Inflammatory Chemokine Transport and Presentation in HEV (2001) (558)
Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin (2009) (557)
DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection. (2002) (555)
Chemokine Requirements for B Cell Entry to Lymph Nodes and Peyer's Patches (2002) (544)
A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2 (1990) (541)
Decreased Bacterial Diversity Characterizes the Altered Gut Microbiota in Patients With Psoriatic Arthritis, Resembling Dysbiosis in Inflammatory Bowel Disease (2015) (539)
A subset of CD4+ thymocytes selected by MHC class I molecules. (1994) (503)
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity (2011) (484)
Role of the commensal microbiota in normal and pathogenic host immune responses. (2011) (473)
Cell-cell adhesion mediated by CD8 and MHC class I molecules (1988) (471)
Transcriptional regulation of Th17 cell differentiation. (2007) (470)
Cytokine Signals Are Sufficient for HIV-1 Infection of Resting Human T Lymphocytes (1999) (459)
The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival (2003) (458)
Bile acid metabolites control Th17 and Treg cell differentiation (2018) (455)
Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. (2012) (451)
Thymic Origin of Intestinal αß T Cells Revealed by Fate Mapping of RORγt+ Cells (2004) (447)
A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development (1994) (444)
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. (1999) (440)
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. (2008) (432)
PKC-θ knockout mice are protected from fat-induced insulin resistance (2004) (431)
The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. (1998) (422)
Signal Transduction Due to HIV-1 Envelope Interactions with Chemokine Receptors CXCR4 or CCR5 (1997) (421)
RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. (2009) (417)
Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis. (2012) (415)
Focused Specificity of Intestinal Th17 Cells towards Commensal Bacterial Antigens (2014) (411)
Flexible use of nuclear import pathways by HIV-1. (2010) (404)
Requirement for association of p56 lck with CD4 in antigen-specific signal transduction in T cells (1991) (403)
BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias (1991) (397)
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring (2017) (397)
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease (2008) (387)
PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes. (2000) (385)
Human Immunodeficiency Virus Type 1 Activates Plasmacytoid Dendritic Cells and Concomitantly Induces the Bystander Maturation of Myeloid Dendritic Cells (2004) (383)
The chemokine SDF1 regulates migration of dentate granule cells. (2002) (373)
Control of Interneuron Fate in the Developing Spinal Cord by the Progenitor Homeodomain Protein Dbx1 (2001) (369)
Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity (1990) (367)
Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells. (1999) (350)
Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates, Like HIV-1 Isolates, Frequently Use CCR5 but Show Promiscuity in Coreceptor Usage (1999) (349)
Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone (2008) (346)
Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk. (1995) (345)
The Role of CXCR4 in Maintaining Peripheral B Cell Compartments and Humoral Immunity (2004) (343)
Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse (2007) (342)
A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells (2010) (330)
Chemokine Receptors: Keys to AIDS Pathogenesis? (1998) (321)
Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity (2014) (316)
c-Maf-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont (2018) (316)
An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses (2015) (306)
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. (2011) (303)
Differences in chemokine coreceptor usage between genetic subtypes of HIV-1. (1998) (300)
Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice. (1993) (299)
CX3CR1+ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22 (2014) (298)
A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1–IRF Complexes (2012) (298)
A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice. (1999) (295)
Pseudotyping with human T-cell leukemia virus type I broadens the human immunodeficiency virus host range (1991) (291)
The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium. (2001) (290)
CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney. (2006) (288)
PKC-theta knockout mice are protected from fat-induced insulin resistance. (2004) (288)
The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes (1985) (287)
The regulation of CD4 and CD8 coreceptor gene expression during T cell development. (1999) (277)
The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system (2006) (277)
The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4 (1988) (275)
Protein Kinase C θ Inhibits Insulin Signaling by Phosphorylating IRS1 at Ser1101* (2004) (274)
Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors. (2005) (271)
Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development (2001) (270)
Requirement for CARMA1 in Antigen Receptor-Induced NF-κB Activation and Lymphocyte Proliferation (2003) (270)
Nuclear Hormone Receptors in T Lymphocytes (2002) (270)
Packaging system for rapid production of murine leukemia virus vectors with variable tropism (1992) (269)
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells (2007) (261)
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes (2002) (259)
The structure of the CD4 and CD8 genes. (1987) (259)
Microbiota Restrict Trafficking of Bacteria to Mesenteric Lymph Nodes by CX3CR1hi Cells (2013) (257)
Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer (2007) (257)
A kinase-independent function of Lck in potentiating antigen-specific T cell activation (1993) (254)
Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes (1993) (248)
How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets. (2009) (243)
Canonical and alternate functions of the microRNA biogenesis machinery. (2010) (241)
Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells. (2004) (239)
The Primate Lentiviral Receptor Bonzo/STRL33 Is Coordinately Regulated with CCR5 and Its Expression Pattern Is Conserved Between Human and Mouse1 (2000) (237)
Releasing the Brakes on Cancer Immunotherapy (2015) (234)
Neutralization Profiles of Primary Human Immunodeficiency Virus Type 1 Isolates in the Context of Coreceptor Usage (1998) (229)
GPR15-Mediated Homing Controls Immune Homeostasis in the Large Intestine Mucosa (2013) (228)
Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk (2000) (227)
Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor (1997) (227)
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. (2001) (226)
A Chemokine, SDF-1, Reduces the Effectiveness of Multiple Axonal Repellents and Is Required for Normal Axon Pathfinding (2003) (223)
Short- and long-term effects of oral vancomycin on the human intestinal microbiota (2016) (221)
RUNX proteins in transcription factor networks that regulate T-cell lineage choice (2009) (220)
Nonredundant Function of Soluble LTα3 Produced by Innate Lymphoid Cells in Intestinal Homeostasis (2013) (219)
Fusion-competent vaccines: broad neutralization of primary isolates of HIV. (1999) (216)
Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4. (1993) (215)
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma (2008) (214)
Polymorphism in the α3 domain of HLA-A molecules affects binding to CD8 (1989) (212)
CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance. (2015) (211)
Protein Kinase C θ Is Critical for the Development of In Vivo T Helper (Th)2 Cell But Not Th1 Cell Responses (2004) (209)
CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity (2011) (208)
Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells (2009) (206)
Reversing behavioral abnormalities in mice exposed to maternal inflammation (2017) (205)
Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage (2001) (202)
The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations (2019) (199)
The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches (2003) (199)
Exclusive and Persistent Use of the Entry Coreceptor CXCR4 by Human Immunodeficiency Virus Type 1 from a Subject Homozygous for CCR5 Δ32 (1998) (196)
A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines (1993) (196)
Transcriptional regulatory networks in Th17 cell differentiation. (2009) (191)
Review: Microbiome in Inflammatory Arthritis and Human Rheumatic Diseases (2016) (185)
Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 Primary Isolates to Antibodies and CD4-Based Reagents Is Independent of Coreceptor Usage (1998) (181)
Regulation of the TCRα repertoire by the survival window of CD4+CD8+ thymocytes (2002) (180)
Protein Kinase C βII Regulates Akt Phosphorylation on Ser-473 in a Cell Type- and Stimulus-specific Fashion*♦ (2004) (179)
CD8αα-Mediated Survival and Differentiation of CD8 Memory T Cell Precursors (2004) (178)
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage (2008) (176)
Use of Coreceptors Other Than CCR5 by Non-Syncytium-Inducing Adult and Pediatric Isolates of Human Immunodeficiency Virus Type 1 Is Rare In Vitro (1998) (173)
Regulation of IL-4 expression by activation of individual alleles. (1998) (172)
Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle. (2005) (172)
Viral receptors of the immunoglobulin superfamily (1989) (171)
Identification of natural RORγ ligands that regulate the development of lymphoid cells. (2015) (170)
An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses (2016) (167)
176 IL-6 Programs TH-17 Cell Differentiation by Promoting the Sequential Engagement of the IL-21 and IL-23 Pathways (2007) (166)
A second subunit of CD8 is expressed in human T cells. (1988) (165)
Role for CXCR6 in Recruitment of Activated CD8+ Lymphocytes to Inflamed Liver1 (2005) (165)
The genome of th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment. (2011) (164)
Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4 (1988) (164)
Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection. (2010) (163)
Modulation of immune homeostasis by commensal bacteria. (2011) (161)
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease (2019) (158)
Small molecule inhibitors of RORγt: Targeting Th17 cells and other applications (2012) (155)
Properties of the depolymerization products of microtubules from mammalian brain. (1974) (154)
Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein increases env incorporation into particles and fusogenicity and infectivity (1993) (153)
Development and function of T cells in mice with a disrupted CD2 gene. (1992) (153)
Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101). (2004) (153)
Identification and sequence of a fourth human T cell antigen receptor chain (1987) (149)
DDX5 and its associated lncRNA Rmrp modulate Th17 cell effector functions (2015) (147)
Segmented filamentous bacteria take the stage (2010) (146)
A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2. (1990) (142)
The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits (1992) (141)
The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer (1987) (141)
An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells. (1997) (139)
Feeding-dependent VIP neuron-ILC3 circuit regulates the intestinal barrier (2020) (132)
Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain. (1994) (131)
Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene. (1991) (130)
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians (2021) (129)
Analysis of the site in CD4 that binds to the HIV envelope glycoprotein. (1990) (128)
Helper T-cell development in the absence of CD4-p56 Ick association (1993) (127)
Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation. (2002) (126)
Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells. (1998) (126)
Analysis of mutations in the V3 domain of gp160 that affect fusion and infectivity (1992) (125)
Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes. (1988) (120)
Cutting Edge: Organogenesis of Nasal-Associated Lymphoid Tissue (NALT) Occurs Independently of Lymphotoxin-α (LTα) and Retinoic Acid Receptor-Related Orphan Receptor-γ, but the Organization of NALT Is LTα Dependent1 (2002) (117)
Unusual intron in the immunoglobulin domain of the newly isolated murine CD4 (L3T4) gene (1987) (116)
CXCR4 acts as a costimulator during thymic β selection (2009) (116)
Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells (2009) (115)
Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T Cell Responses (2018) (113)
Segmented Filamentous Bacteria Provoke Lung Autoimmunity by Inducing Gut-Lung Axis Th17 Cells Expressing Dual TCRs. (2017) (113)
CD11chigh Dendritic Cell Ablation Impairs Lymphopenia-Driven Proliferation of Naive and Memory CD8+ T Cells1 (2005) (112)
Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs (2012) (108)
Runx3 Regulates Integrin αE/CD103 and CD4 Expression during Development of CD4−/CD8+ T Cells1 (2005) (108)
The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy. (2011) (106)
Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. (2002) (106)
Protein kinase C-θ: signaling from the center of the T-cell synapse (2002) (105)
SIRT1 deacetylates RORγt and enhances Th17 cell generation (2015) (102)
Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis. (2007) (102)
Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells (1992) (100)
Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation. (2017) (100)
Harnessing CD4+ T cell responses in HIV vaccine development (2013) (98)
Broad host range of human T-cell leukemia virus type 1 demonstrated with an improved pseudotyping system (1996) (98)
Progress Toward a Human CD4/CCR5 Transgenic Rat Model for De Novo Infection by Human Immunodeficiency Virus Type 1 (2002) (98)
The Chemokine Stromal Cell-Derived Factor-1 Promotes the Survival of Embryonic Retinal Ganglion Cells (2003) (94)
PKCθ Signals Activation versus Tolerance In Vivo (2004) (94)
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin (2012) (93)
Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF-kappaB and MAPK activation to selectively control cytokine production. (2008) (93)
Dendritic Cell-Mediated trans-Enhancement of Human Immunodeficiency Virus Type 1 Infectivity Is Independent of DC-SIGN (2006) (92)
CD2 regulates the positive selection and function of antigen-specific CD4- CD8+ T cells. (1997) (91)
Characterization of an expressed CDS-associated Ti γ-chain reveals Cγ domain polymorphism (1987) (88)
Participation of CD4 coreceptor molecules in T-cell repertoire selection (1991) (87)
Runx1 Protects Hematopoietic Stem/Progenitor Cells from Oncogenic Insult (2007) (87)
Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation (2017) (87)
CD8alphaalpha-mediated survival and differentiation of CD8 memory T cell precursors. (2004) (86)
Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis (2005) (85)
A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells. (2010) (85)
Apoptotic Signaling through the β-Adrenergic Receptor (2000) (83)
Functional and Antigenic Characterization of Human, Rhesus Macaque, Pigtailed Macaque, and Murine DC-SIGN (2001) (82)
Dynamic MicroRNA Gene Transcription and Processing during T Cell Development (2012) (82)
Species-Specific Restriction of Apobec3-Mediated Hypermutation (2007) (80)
Distinct Polysaccharide Utilization Profiles of Human Intestinal Prevotella copri Isolates. (2019) (80)
Caspase-8 and c-FLIPL Associate in Lipid Rafts with NF-κB Adaptors during T Cell Activation* (2007) (78)
Epigenetic gene silencing by Runx proteins (2004) (76)
Lymphoid tissue inducer cells in intestinal immunity. (2006) (75)
Hiding in Plain Sight: How HIV Evades Innate Immune Responses (2011) (73)
Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells (2018) (72)
The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins. (1998) (72)
Antiviral immune responses in Itk-deficient mice (1997) (72)
SIRT1 deacetylates RORγt and enhances Th17 cell generation (2015) (71)
Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression. (2002) (71)
CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation (1995) (70)
Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation (1997) (69)
Actin Dynamics Regulates Dendritic Cell-Mediated Transfer of HIV-1 to T Cells (2016) (69)
Chemokine receptors in lymphoid organ homeostasis. (1999) (68)
G protein-coupled receptors in HIV and SIV entry: new perspectives on lentivirus-host interactions and on the utility of animal models. (1998) (68)
Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking (2009) (67)
Regulation of DNA methylation dictates Cd4 gene expression during development of helper and cytotoxic T cell lineages (2015) (66)
NK cell-activating receptors require PKC-theta for sustained signaling, transcriptional activation, and IFN-gamma secretion. (2008) (64)
Generation and Characterization of Ecto-ADP-Ribosyltransferase ART2.1/ART2.2-Deficient Mice (2002) (63)
DICER 1 deficit induces Alu RNA toxicity in age-related macular degeneration (62)
Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells. (2005) (62)
The SDF‐1/CXCR4 pathway and the development of the cerebellar system (2005) (62)
Molecular diversity of the human T-gamma constant region genes. (1987) (62)
Disruption of CD8‐dependent negative and positive selection of thymocytes is correlated with a decreased association between CD8 and the protein tyrosine kinase, p56lck (1992) (61)
Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells. (2010) (60)
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells (2007) (59)
The gene encoding the T-cell surface protein T4 is located on human chromosome 12. (1986) (59)
Murine T Cells Potently Restrict Human Immunodeficiency Virus Infection (2004) (59)
The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity (2015) (58)
Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy (2019) (55)
Lineage Diversion of T Cell Receptor Transgenic Thymocytes Revealed by Lineage Fate Mapping (2008) (53)
Myd88 Is Required for an Antibody Response to Retroviral Infection (2009) (53)
The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development. (2004) (53)
Natural resistance to HIV? (1996) (52)
The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development. (1998) (52)
Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8. (1989) (51)
BCR selection and affinity maturation in Peyer’s patch germinal centres (2020) (51)
Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells. (2019) (50)
Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells. (2011) (48)
Expression pattern of HIV-1 coreceptors on T cells: implications for viral transmission and lymphocyte homing. (1997) (48)
Apoptotic signaling through the beta -adrenergic receptor. A new Gs effector pathway. (2000) (47)
Differential requirements for CD4 in TCR-ligand interactions. (1999) (47)
Neutralizing Antibodies in Sera from Macaques Immunized with Attenuated Simian Immunodeficiency Virus (1998) (47)
Attenuation of Acute Graft-versus-Host Disease in the Absence of the Transcription Factor RORγt (2012) (47)
Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene. (1989) (46)
The cytoplasmic tail of CD4 is required for inhibition of human immunodeficiency virus type 1 replication by antibodies that bind to the immunoglobulin CDR3-like region in domain 1 of CD4 (1995) (46)
Thymocyte lineage commitment: is it instructed or stochastic? (1994) (45)
Several CD4 domains can play a role in human immunodeficiency virus infection in cells (1991) (45)
The thymus leukemia antigen binds human and mouse CD8 (1991) (44)
Cutting edge: organogenesis of nasal-associated lymphoid tissue (NALT) occurs independently of lymphotoxin-alpha (LT alpha) and retinoic acid receptor-related orphan receptor-gamma, but the organization of NALT is LT alpha dependent. (2002) (44)
Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors. (2013) (44)
Protein kinase C-theta;: signaling from the center of the T-cell synapse. (2002) (44)
Protein Kinase C Is Critical for the Development of In Vivo T Helper ( Th ) 2 Cell But Not Th 1 Cell Responses (2004) (43)
Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection (2008) (43)
A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection (2019) (43)
Role of the nuclear hormone receptor ROR gamma in transcriptional regulation, thymocyte survival, and lymphoid organogenesis. (1999) (42)
The T4 glycoprotein is a cell-surface receptor for the AIDS virus. (1986) (42)
After Hrs with HIV (2003) (40)
Studies of HIV‐1 envelope glycoprotein‐mediated fusion using a simple fluorescence assay (1996) (40)
Microbiota: host interactions in mucosal homeostasis and systemic autoimmunity. (2013) (40)
Runx-CBFβ complexes control Foxp3 expression in regulatory T cells (2009) (39)
Inhibition of thymocyte negative selection by T cell receptor antagonist peptides (1996) (39)
RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation (2011) (39)
CD4-Specific Transgenic Expression of Human Cyclin T1 Markedly Increases Human Immunodeficiency Virus Type 1 (HIV-1) Production by CD4+ T Lymphocytes and Myeloid Cells in Mice Transgenic for a Provirus Encoding a Monocyte-Tropic HIV-1 Isolate (2006) (39)
Phorbol ester-induced down modulation of tailless CD4 receptors requires prior binding of gp120 and suggests a role for accessory molecules (1995) (38)
Nonequivalent effects of PKC activation by PMA on murine CD4 and CD8 cell‐surface expression (1988) (36)
Coreceptor Specificity of Temporal Variants of Simian Immunodeficiency Virus Mne (1999) (36)
Diversity of class I HLA molecules: functional and evolutionary interactions with T cells. (1989) (35)
Relief of Preintegration Inhibition and Characterization of Additional Blocks for HIV Replication in Primary Mouse T Cells (2008) (35)
Longman, R.S. et al. CX(3)CR1(+) mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22. J. Exp. Med. 211, 1571-1583 (2014) (35)
Transcription factor AP4 modulates reversible and epigenetic silencing of the Cd4 gene (2011) (34)
miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation. (2016) (33)
Requirement for kinase activity of CD4-associated p56lck in antibody-triggered T cell signal transduction. (1994) (33)
CD2-deficient mice generate virus-specific cytotoxic T lymphocytes upon infection with lymphocytic choriomeningitis virus. (1993) (33)
HIV's vagina travelogue. (2007) (32)
Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A New Model for Investigating HIV-1 Transmission and Treatment Efficacy (2013) (32)
Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection. (2018) (31)
HIV immunology needs a new direction (2008) (31)
Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation (2021) (30)
HIV: master of the host cell (2001) (30)
Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice (2017) (30)
Corrected CD4 sequence (1988) (30)
Human microbiome science: vision for the future, Bethesda, MD, July 24 to 26, 2013 (2014) (29)
Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling (2017) (29)
Runx3 regulates integrin αE/CD103 and CD4 expression during development of CD4−/CD8+ T cells (2005) (29)
Glycosylphosphatidylinositol-anchored CD4/Thy-1 chimeric molecules serve as human immunodeficiency virus receptors in human, but not mouse, cells and are modulated by gangliosides (1991) (29)
Deciphering the regulatory landscape of fetal and adult γδ T‐cell development at single‐cell resolution (2020) (28)
CD4 function in thymocyte differentiation and T cell activation. (1993) (28)
Itk and Fyn Make Independent Contributions to T Cell Activation (1997) (28)
THE REGULATION OF CD 4 AND CD 8 CORECEPTOR GENE EXPRESSION DURING T CELL DEVELOPMENT (1999) (27)
A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation (2022) (27)
Human microbiome science: vision for the future, (2014) (27)
The regulation and function of the CD4 coreceptor during T lymphocyte development. (1996) (25)
Functional and Molecular Analysis of the Double-Positive Stage-Specific CD8 Enhancer E8III during Thymocyte Development1 (2005) (24)
Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development (2018) (24)
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease (2020) (24)
Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo (2009) (23)
The transcription factor ThPOK acts late in helper T cell lineage specification and suppresses Runx-mediated commitment to the cytotoxic T cell lineage (2008) (23)
CD 2 Regulates the Positive Selection and Function of Antigen-Specific CD 4 Ï CD 8 " T Cells (1997) (22)
Translating microbiome futures (2018) (22)
Cell fusion mediated by interaction of a hybrid CD4.CD8 molecule with the human immunodeficiency virus type 1 envelope glycoprotein does occur after a long lag time (1993) (22)
T-cell receptor genes in autoimmune mice: T-cell subsets have unexpected T-cell receptor gene programs. (1987) (22)
Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development (2001) (22)
CD4+ T-lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. (1994) (21)
The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells (2019) (21)
Patterns of T cell receptor gamma gene rearrangement and expression in B and T lymphoid malignancies. (1988) (21)
The Prevotella copri complex comprises four distinct clades that are underrepresented in Westernised populations (2019) (19)
SIRT 1 deacetylates ROR t and enhances Th 17 cell generation (2015) (18)
Functional and Molecular Analysis of the Double-Positive Stage-Specific CD8 Enhancer E8III during Thymocyte Development (2005) (17)
Disrupted development of thymocytes expressing a transgenic TCR upon CD4 overexpression. (1995) (17)
Gut microbiome dysbiosis in antibiotic-treated COVID-19 patients is associated with microbial translocation and bacteremia (2022) (17)
Mouse brain CD4 transcripts encode only the COOH-terminal half of the protein (1988) (17)
Visualization of mucosal homeostasis via single‐ and multiphoton intravital fluorescence microscopy (2012) (16)
Virus-host interactions: new insights from the small RNA world (2005) (16)
Do the Microbiota Influence Vaccines and Protective Immunity to Pathogens? If So, Is There Potential for Efficacious Microbiota-Based Vaccines? (2018) (16)
Selective cell adhesion of neuronal cell lines. (1977) (15)
Characterization of an expressed CD3-associated Ti gamma-chain reveals C gamma domain polymorphism. (1987) (15)
Immunodeficiency Viruses: Not enough sans Nef (1994) (15)
Insertion of Ia and H-2 alloantigens into model membranes. (1979) (15)
Role for CXCR 6 in Recruitment of Activated CD 8 Lymphocytes to Inflamed Liver 1 (2004) (14)
Structural comparison of murine Ia antigens determined by the I-A and I-E subregions. (1979) (13)
Author Correction: Bile acid metabolites control TH17 and Treg cell differentiation (2020) (13)
Bile acid metabolites control TH17 and Treg cell differentiation (2019) (13)
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes (2020) (13)
The CD4 Molecule (1996) (13)
The CD 4 / CD 8 Lineage Choice : New Insights into Epigenetic Regulation during T Cell Development (2004) (13)
The Kinase‐dependent Function of Lck in T‐Cell Activation Requires an Intact Site for Tyrosine Autophosphorylation a (1995) (13)
The epigenetic landscape of lineage choice: lessons from the heritability of CD4 and CD8 expression. (2012) (13)
Regulated Movement of CD4 In and Out of the Immunological Synapse1 (2008) (12)
CD11c Dendritic Cell Ablation Impairs Lymphopenia-Driven Proliferation of Naive and Memory CD8 T Cells (2005) (11)
Retraction Note: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions (2018) (11)
c-MAF–dependent perivascular macrophages regulate diet-induced metabolic syndrome (2021) (11)
A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV (2020) (11)
The Orphan Nuclear Receptor ROR g t Directs the Differentiation Program of Proinflammatory IL-17 + T Helper Cells (2014) (11)
Asymmetry and Immune Memory (2007) (10)
NK cell activating receptors require PKC θ for sustained signaling, transcriptional activation and IFN- γ secretion (2008) (10)
How Thymocytes Achieve Their Fate (2016) (9)
The function of the CD4 coreceptor in the development of T cells. (1995) (9)
Arkadia-SKI/SnoN signaling differentially regulates TGF-β–induced iTreg and Th17 cell differentiation (2021) (9)
Cell and viral regulatory elements enhance the expression and function of a human immunodeficiency virus inhibitory gene (1997) (9)
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease (2008) (9)
The CD4 molecule. Roles in T lymphocytes and in HIV disease. Introduction. (1996) (8)
A rare intestinal infection with systemic effects. (2012) (8)
Human GLI-2 Is a Tat Activation Response Element-Independent Tat Cofactor (2001) (7)
Neuronal Cell Adhesion (1976) (7)
Role of cell-to-cell interactions in T lymphocyte development and activation. (1989) (7)
Regulation of RORγt in Inflammatory Lymphoid Cell Differentiation. (2015) (7)
Differential involvement of protein tyrosine kinases p56lck and p59fyn in T cell development. (1992) (6)
c-MAF dependent perivascular macrophages regulate diet induced metabolic syndrome (2021) (6)
Gut microbiome dysbiosis during COVID-19 is associated with increased risk for bacteremia and microbial translocation (2021) (6)
c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont (2018) (5)
Author Correction: c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont (2019) (5)
c-Maf-dependent regulatory T cells mediate immunological tolerance to intestinal microbiota (2017) (5)
TH17 cell heterogeneity and its role in tissue inflammation (2023) (5)
Vitro Immunodeficiency Virus Type 1 Is Rare In Pediatric Isolates of Human Non-Syncytium-Inducing Adult and Use of Coreceptors Other Than CCR 5 by (1998) (5)
Lung eosinophils elicited during allergic and acute aspergillosis express RORγt and IL-23R but do not require IL-23 for IL-17 production (2021) (5)
Selection and lineage specification in the thymus: commitment 4-stalled. (2005) (5)
Tcf1 and Lef1 pack their own HDAC (2016) (4)
Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions (2016) (4)
VIP-producing enteric neurons interact with innate lymphoid cells to regulate feeding-dependent intestinal epithelial barrier functions (2019) (4)
Structure and potential function of the murine L3T4 molecule. (1987) (4)
Identification of Potent and Selective RORγ Antagonists (2013) (4)
Response to Comment on "Thymic Origin of Intestinal αß T Cells Revealed by Fate Mapping of RORγt+ Cells" (2005) (4)
Signal transduction during T cell development. (1994) (4)
New traffic light on Th17 Avenue (2017) (4)
production B and MAPK activation to selectively control cytokine κ via Carma1 for NF- Multiple ITAM-coupled NK cell receptors engage the Bcl10/Malt1 complex (2013) (4)
Deciphering the Regulatory Landscape of γδ T Cell Development by Single-Cell RNA-Sequencing (2018) (3)
Distinct polysaccharide growth profiles of human intestinal Prevotella copri isolates (2019) (3)
Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element (2022) (3)
CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element (2022) (3)
Identification and characterization of a T-cell-specific enhancer adjacent to the murine CD4 gene (1991) (3)
RNAi in human monocyte-derived dendritic cells using shRNA vectors (2010) (3)
Inﬂammatory Chemokine Transport and Presentation in HEV: A Remote Control Mechanism for Monocyte Recruitment to Lymph Nodes in Inﬂamed Tissues (2001) (3)
Immunology. Asymmetry and immune memory. (2007) (3)
Specific targeting of intestinal Prevotella copri by a Listeria monocytogenes bacteriocin (2019) (3)
Human Th 17 cells are susceptible to HIV and are perturbed during infection (2010) (2)
Identification of unique bile acid-metabolizing bacteria from the microbiome of centenarians (2020) (2)
Microbiota-instructed regulatory T cell differentiation is mediated by a distinct RORγt+ antigen presenting cell subset (2022) (2)
SPNS2 enables T cell egress from lymph nodes during an immune response (2021) (2)
Abstract A06: The chemokine receptor CXCR4 is essential for the maintenance of T cell acute lymphoblastic leukemia. (2015) (2)
RORα enforces stability of the T-helper-17 cell effector program (2020) (2)
27: IL-17 is Required for CD4-Mediated GVHD (2008) (2)
Multi-step Th17 differentiation in response to segmented filamentous bacteria in the mouse intestine (2016) (2)
Specific microbiota direct the differentiation of Th17 cells in the mucosa of the small intestine (2013) (2)
Rorα Enforces Stability of the T-Helper-17 Cell Effector Program (2020) (1)
Role of microbiota and transcription factors in control of Th17 cell differentiation (2009) (1)
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin (2012) (1)
Antibody engineering: Research and application of genes encoding immunoglobulins (1994) (1)
Antigen presentation by type 3 innate lymphoid cells instructs the differentiation of gut microbiota-specific regulatory T cells (2021) (1)
Use of Gene Transfer in the Isolation of Cell Surface Receptor Genes (1987) (1)
HistonemacroH 2 A 1 isconcentrated in the inactiveXchromosome of femalemammals (1998) (1)
Studies on cell recognition in the developing brain. (1977) (1)
Analysis ofMutations intheV3Domainofgpl60ThatAffect Fusion andInfectivity (1992) (1)
Immune cell control of nutrient absorption (2021) (1)
Thymocyte DevelopmentIIIE 8 EnhancerDouble-Positive Stage-Specific CD 8 Functional and Molecular Analysis of the (2005) (1)
Transcriptional control of RORγt across innate and adaptive immunity. (2016) (1)
Differential Requirements for CD 4 in TCR-Ligand Interactions 1 (1999) (1)
Factor ROR Disease in the Absence of the Transcription Attenuation of Acute Graft-versus-Host (2012) (1)
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes. (2021) (1)
Transcriptional regulatory networks that promote and restrict identities and functions of intestinal innate lymphoid cells (2018) (1)
Microbial Regulation of CD14+ Human Intestinal DCs Support ILC Production of IL‐22 in IBD: O‐24 YI (2012) (0)
Table of Contents (2012) (0)
Signal Transduction in Immunocytes (2014) (0)
Critical role of the transcription factors IRF 1 and BATF in preparing the chromatin landscape during Type 1 regulatory cell differentiation (2018) (0)
Attenuation of Acute GvHD in the Absence of the Transcription Factor ROR γ t (2012) (0)
Abstract B167: Antigen-presenting cells as coordinators of T-cell responses to gut microbiota (2019) (0)
23 TLR/MYD88-Dependent Production of Il1β and IL-23 by Intestinal Dendritic Cells Support Increased Ilc Production of IL-22 in IBD (2013) (0)
S1676 The Presence of a Distinct Population of Lamina Propria TH17/FOXP3+ Cells in Crohn's Disease (2009) (0)
Figure 2, Stability of ML209 in PBS buffer (pH 7.4, 23°C) plotted as LC peak area vs time for a 48 hr period (2013) (0)
Table 3, Structure-activity relationship study of the diphenylpropanamide series (2013) (0)
Neuroprotective roles of fractalkine in multiple sclerosis: Characterization of novel humanized animal model (2018) (0)
Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development (2018) (0)
Lymphocytes to Inflamed Liver + CD8Role for CXCR6 in Recruitment of Activated (0)
T cell development (PP-058) (2010) (0)
A comprehensive map of the dendritic cell transcriptional network engaged upon innate sensing of HIV (2019) (0)
Critical role for the microbiota in limiting inflammatory intestinal T cell responses (2018) (0)
Human microbiome science: vision for the future, Bethesda, MD, July 24 to 26, 2013 (2014) (0)
Th17 (WS-014) Chairpersons: Akihiko Yoshimura, Joseph E. Craft (2010) (0)
Table 2, Activity profile of the ROR qHTS (2013) (0)
Identification of unique bile acid-metabolizing bacteria from the 1 microbiome of centenarians 2 3 (2020) (0)
Abstract IA09: The commensal microbiota as instructors and arbiters of homeostatic and pathogenic immune responses (2016) (0)
S1701 A Crucial Role of Rorgamma Expressing TH17 Cells in Chronic Intestinal Inflammation (2008) (0)
GM-CSF treatment enables mice transgenic for CD4-specific expression of human CD4, CCR5 and CyclinT1 to support in vitro and in vivo HIV infection (2012) (0)
Carma1 Regulates T Cell Memory Responses In A Murine Model Of Allergic Asthma (2011) (0)
Table 4, Profiling results for ML209 in a panel of 21 nuclear receptors for antagonistic activity (2013) (0)
PS1-19 The aryl hydrocarbon receptor modulates the Th17 and Treg balance and gut immunity (2010) (0)
Abstract B198: Dissection of RORγt functions in lymphoid cell fate determination and differentiation (2019) (0)
Microbial Regulation of CD141 Human Intestinal DCs Support ILC Production of IL‐22 in IBD: P‐241 YI (2012) (0)
Comment After Hrs with HIV (2003) (0)
NOTES Dendritic Cell-Mediated trans -Enhancement of Human Immunodeﬁciency Virus Type 1 Infectivity Is Independent of DC-SIGN (cid:1) (2007) (0)
Interplay between pre-TCR, CXCR4 and laminin10/11 during thymic β selection (85.8) (2009) (0)
For the T-cell surface protein coding t4 dna and use of t4-fragments in the treatment of AIDS (1987) (0)
Abstract A080: Balance of commensal bacteria specific Th17 and RORγt+ Treg cells in intestinal homeostasis and inflammation (2016) (0)
Attenuated Acute Graft-Versus-Host Disease Following Allogeneic Stem Cell Transplantation In the Absence of RORγt. (2010) (0)
DNA encoding the T cell surface protein T4 and use of T-4 in the treatment of AIDS (1988) (0)
Retraction Note: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions (2018) (0)
Selective metabolic redundancy of Gpi1 allows for specific inhibition of inflammatory Th17 cells (2019) (0)
SCORCh.R: Clustering and visualization of sequencing derived multiple transcription factor loci (2005) (0)
Protein Kinase C (cid:1) Inhibits Insulin Signaling by Phosphorylating IRS1 at (2004) (0)
GENE EXPRESSION & SIGNALING IN THE IMMUNE SYSTEM (2010) (0)
Electron Solvation in Finite Systems : Femtosecond Dynamics of Iodide z ( Water ) n Anion Clusters (1999) (0)
CX3CR1+ intestinal mononuclear phagocytes regulate induction and maintenance of tolerogenic intestinal immune responses (P3343) (2013) (0)
Lymphocyte development in genetically manipulated mice. (1994) (0)
1361 Inﬂammatory Chemokine Transport and Presentation in HEV: A Remote Control Mechanism for Monocyte Recruitment to Lymph Nodes in Inﬂamed (2001) (0)
Siv hiv pseudotypes demonstrate envelope mediated host range (1992) (0)
Incorporation of ia antigens into lipid vesicles. Abstr. (1978) (0)
Short Course 1 Intersections Between Brain and Immune System in Health and Disease (2017) (0)
The microbiota conditions CX3CR1+ intestinal mononuclear phagocytes to limit intestinal inflammation. (MUC2P.822) (2014) (0)
866 Microbiota Support Increased Production of IL-22 by Lamina Propria Innate Lymphoid Cells in Patients With IBD (2012) (0)
P-127 GPR15 Expression in Mouse and Human (2016) (0)
Table 1, Itemized protocol for RORγ, VP16 and RORγ reporter assays used in the qHTS and follow up studies (2013) (0)
Crystal structure of the orphan nuclear receptor RORalpha ligand-binding domain in complex with 4alpha-caboxyl, 4beta-methyl-zymosterol (4ACD8) (2015) (0)
The glutamine residue of the conserved GGQ motif in Saccharomyces cerevisiae release factor eRF1 is methylated by the product of the YDR140w gene. Vol. 280 (2005) 2439-2445 (2005) (0)
Multimodal characterization of antigen-specific CD8+ T cells across SARS-CoV-2 vaccination and infection (2023) (0)
Not enough sans Nef The nefgenes of HIV and SIV are dispensable in vitro, but are essential for viral spread and disease progression in vivo. Nef-induced down-regulation of CD4, the viral receptor, may be the key to this requirement. (1994) (0)
Role of the orphan nuclear receptor ROR?t in immune system homeostasis (2007) (0)
Arrangements and Rearrangements of the Human T‐cell Receptor Gamma Gene a (1987) (0)
T4: A T-Cell Surface Protein Mediating Cell-Cell and Cell-AIDS Virus Interactions (1987) (0)
Abstract #10: Sickness Behavior and Gut-Brain Signaling Via Vagus Nerve in Infected Mice (2019) (0)
Regulated Movement of CD 4 In and Out of the Immunological Synapse 1 (2008) (0)
The role of CD8Î² in T cell development may be due to its regulation of CD8Î±-associated Lck kinase activity (1997) (0)
Protein Kinase C II Regulates Akt Phosphorylation on Ser-473 in a Cell Type- and Stimulus-specific Fashion*□S (2004) (0)
Amino-terminal region of foxp3 performs multiple functions in regulating transcription (2007) (0)
Tu1236 DANGEROUS LIAISONS: CO-HOUSING WITH MIF-/- MICE TRIGGERS EARLY AND SEVERE COLITIS IN IL10-/- MICE (2020) (0)
Th17 / Treg (SY2-1) Chairpersons: Shimon Sakaguchi, Daniel Cua (2010) (0)
tropism . murine leukemia virus vectors with variable Packaging system for rapid production of (2003) (0)
Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. (2023) (0)
Epigenetic Programming during thymic development sets the stage for optimal function in effector T cells via DNA demethylation (2021) (0)
DNA encoding the T cell surface protein T4, and using T4 fragments in the treatment of AIDS (1988) (0)
Interplay between pre-TCR, CXCR4 and laminin10/11 during thymic {beta} selection (2009) (0)
Abstract A073: Epigenetic regulation of the Cd4 locus (2016) (0)
miRNAs are critical for the regulation of RAG expression and secondary Ig rearrangement in peripheral B lymphocytes (2016) (0)
Segmented filamentous bacteria take the stage II (2010) (0)
(histocompatibility antigens/liposomes/radioimmunoassay) (2016) (0)
Philadelphia chromosome-positive human the BCR / ABL tyrosine kinase oncogene of BCR first exon sequences specifically activate (2003) (0)
Expression of the fractalkine receptor, CX3CR1, characterizes a subpopulation of intestinal antigen sampling dendritic cells (2003) (0)
Envelope Pseudotypes of HIV and HTLV (1991) (0)
The role of the enteric microbiota in T cell differentiation (2011) (0)
Balance of Commensal Bacteria-Specific Th17 and RORγt+ Treg Cells in Intestinal Homeostasis and Inflammation (2016) (0)
Annual review of immunology, vol. 26, 2008 (2009) (0)
S30 Th17 cells mediate intestinal fibrosis in mice (2010) (0)
This information is current as Three-Decade Journey From the Thymus to the Mucosa : A (2017) (0)
Unmasking two stages of interferon signaling in dendritic cells infected with HIV-1 (2016) (0)
Arkadia-SKI/SnoN signaling cascade differentially regulates TGF-β-induced iTreg and Th17 cell differentiation (2021) (0)
Glasmacher IRF Complexes − of Immune-Specific AP-1 A Genomic Regulatory Element That Directs Assembly and Function (2013) (0)
SIRT1 enhances Th17 cell generation by deacetylating RORγt (P1163) (2013) (0)
Publisher Correction: A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation (2022) (0)
INVESTIGATING THE ROLE OF ROR{gamma}T IN HUMAN TH17 CELLS (2009) (0)
Quantitative Measurements of HIV-1 and Dextran Capture by Human Monocyte-derived Dendritic Cells (MDDCs). (2016) (0)
Structural Differences Between the Ia Antigens Determined by the I-A and I-C Subregions (1978) (0)
Figure 1, Examples of RORγt antagonists (2013) (0)
Human microbiome science (2014) (0)
BCR selection and affinity maturation in Peyer’s patch germinal centres (2020) (0)
Identification andCharacterization ofa T-Cell-Specific Enhancer Adjacent totheMurineCD4Gene (1991) (0)
From the Thymus to the Mucosa: A Three-Decade Journey (2017) (0)
Provocateurs of autoimmunity within the gut microbiota (2022) (0)
Conserved Between Human and Mouse with CCR5 and Its Expression Pattern Is Bonzo/STRL33 Is Coordinately Regulated The Primate Lentiviral Receptor (2000) (0)
Feeding-dependent VIP neuron–ILC3 circuit regulates the intestinal barrier (2020) (0)
Expression of Functional Human Epstein-Barr Virus/C3d Receptor ([CR2] CD21) on Insulinoma Cell Line: Induction of Tumor Rejection but Not Diabetes in Syngeneic Rats (1991) (0)
IL‐17 is Required for CD4‐Mediated Graft‐Versus‐Host Disease (2008) (0)
Scheme 1, Synthesis of probe molecule (2013) (0)
E16 Transcriptional regulation and role of the commensal microbiota in Th17 cell differentiation (2010) (0)
Abstract A098: Helicobacter-specific T cell responses in gut homeostasis and disease (2016) (0)
SIRT1 enhances Th17 cell generation by deacetylating ROR{gamma}t (P1163) (2013) (0)
A comprehensive map of the human dendritic cell HIV-response transcriptional network (2019) (0)
The Microbiota Limit CX3CR1+ Cell-Dependent Trafficking of a Pathogenic Bacterium to the Mesenteric Lymph Nodes. (71.9) (2012) (0)
Lymphoid Cells in Intestinal Homeostasis Produced by Innate 3 α Nonredundant Function of Soluble LT (2013) (0)
Targeted gastrointestinal tract homing of regulatory T-cells reduces acute graft-versus-host disease severity by simulating an increase in Treg dose in vivo (2021) (0)

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