Dan Peer
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Dan Peer's Degrees
- PhD Biotechnology Tel Aviv University
- Masters Biotechnology Tel Aviv University
- Bachelors Biotechnology Tel Aviv University
Why Is Dan Peer Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dan Peer is a Professor and the Director of the Laboratory of Precision NanoMedicine at Tel Aviv University . He is also the Vice President for Research and Development at TAU. In 2017 he co-founded and acts as the managing director of SPARK Tel Aviv, Center for Translational Medicine. From 2016–2020 he was the chair of the TAU Cancer Biology Research Center.
Dan Peer's Published Works
Published Works
- Nanocarriers as an emerging platform for cancer therapy. (2007) (6245)
- Progress and challenges towards targeted delivery of cancer therapeutics (2018) (1174)
- Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target (2008) (481)
- Nanoparticle hydrophobicity dictates immune response. (2012) (375)
- The systemic toxicity of positively charged lipid nanoparticles and the role of Toll-like receptor 4 in immune activation. (2010) (349)
- Polysaccharides as building blocks for nanotherapeutics. (2012) (273)
- Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1 (2007) (268)
- Nanoparticles for Imaging, Sensing, and Therapeutic Intervention (2014) (237)
- Loading mitomycin C inside long circulating hyaluronan targeted nano‐liposomes increases its antitumor activity in three mice tumor models (2004) (216)
- Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions. (2017) (210)
- RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice. (2010) (204)
- Tumor-targeted hyaluronan nanoliposomes increase the antitumor activity of liposomal Doxorubicin in syngeneic and human xenograft mouse tumor models. (2004) (202)
- Hyaluronan-coated nanoparticles: the influence of the molecular weight on CD44-hyaluronan interactions and on the immune response. (2011) (201)
- RNAi-based nanomedicines for targeted personalized therapy. (2012) (143)
- A modular platform for targeted RNAi therapeutics (2018) (139)
- Paclitaxel-clusters coated with hyaluronan as selective tumor-targeted nanovectors. (2010) (138)
- Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes (2018) (136)
- Special delivery: targeted therapy with small RNAs (2011) (133)
- Next-Generation Lipids in RNA Interference Therapeutics. (2017) (132)
- CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy (2020) (130)
- Localized RNAi therapeutics of chemoresistant grade IV glioma using hyaluronan-grafted lipid-based nanoparticles. (2015) (129)
- On the issue of transparency and reproducibility in nanomedicine (2019) (128)
- Systemic Gene Silencing in Primary T Lymphocytes Using Targeted Lipid Nanoparticles. (2015) (117)
- Cell-specific uptake of mantle cell lymphoma-derived exosomes by malignant and non-malignant B-lymphocytes. (2015) (108)
- Paving the Road for RNA Therapeutics (2020) (102)
- A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes (2020) (102)
- Altering the immune response with lipid-based nanoparticles. (2012) (97)
- Triggered ferroptotic polymer micelles for reversing multidrug resistance to chemotherapy. (2019) (96)
- Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation. (2017) (94)
- Reshaping the future of nanopharmaceuticals: ad iudicium. (2011) (91)
- Hyaluronan is a key component in cryoprotection and formulation of targeted unilamellar liposomes. (2003) (90)
- Modulation of drug resistance in ovarian adenocarcinoma using chemotherapy entrapped in hyaluronan-grafted nanoparticle clusters. (2014) (87)
- Fluoxetine Inhibits Multidrug Resistance Extrusion Pumps and Enhances Responses to Chemotherapy in Syngeneic and in Human Xenograft Mouse Tumor Models (2004) (87)
- Personalized Hydrogels for Engineering Diverse Fully Autologous Tissue Implants (2018) (83)
- Precision nanomedicine in neurodegenerative diseases. (2014) (82)
- Fluoxetine and reversal of multidrug resistance. (2006) (76)
- Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics-An innate immune system standpoint. (2017) (75)
- Immunotoxicity derived from manipulating leukocytes with lipid-based nanoparticles. (2012) (73)
- Omics-based nanomedicine: the future of personalized oncology. (2014) (73)
- Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles (2020) (73)
- Corneal gene therapy. (2007) (72)
- Hyaluronan-grafted particle clusters loaded with Mitomycin C as selective nanovectors for primary head and neck cancers. (2011) (66)
- Monoclonal antibody-based molecular imaging strategies and theranostic opportunities (2020) (66)
- Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies (2015) (66)
- AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes (2006) (62)
- Transforming Nanomedicines From Lab Scale Production to Novel Clinical Modality. (2016) (62)
- Hyaluronan grafted lipid-based nanoparticles as RNAi carriers for cancer cells. (2013) (61)
- Nanomedicine as an emerging platform for metastatic lung cancer therapy (2015) (59)
- Tumor targeting profiling of hyaluronan-coated lipid based-nanoparticles. (2014) (56)
- Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond. (2017) (56)
- Modulation of Immune Response Using Engineered Nanoparticle Surfaces. (2016) (55)
- A daunting task: manipulating leukocyte function with RNAi (2013) (54)
- RNAi nanomedicines: challenges and opportunities within the immune system (2010) (54)
- Triggered-release polymeric conjugate micelles for on-demand intracellular drug delivery (2015) (54)
- Principles for designing an optimal mRNA lipid nanoparticle vaccine (2021) (53)
- Overcoming multidrug resistance with nanomedicines (2015) (51)
- Polysarcosine-Functionalized Lipid Nanoparticles for Therapeutic mRNA Delivery (2020) (50)
- Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles. (2021) (49)
- Modulating cancer multidrug resistance by sertraline in combination with a nanomedicine. (2014) (48)
- Physicochemical evaluation of a stability-driven approach to drug entrapment in regular and in surface-modified liposomes. (2000) (45)
- Treatment of resistant human colon cancer xenografts by a fluoxetine-doxorubicin combination enhances therapeutic responses comparable to an aggressive bevacizumab regimen. (2009) (45)
- Quaternized starch-based carrier for siRNA delivery: from cellular uptake to gene silencing. (2014) (43)
- Toxicity profiling of several common RNAi-based nanomedicines: a comparative study (2014) (42)
- Nanocarriers as an Emerging Platform for Cancer Therapy (2020) (39)
- Harnessing nanomedicine for therapeutic intervention in glioblastoma (2016) (38)
- Current Progress in Non-viral RNAi-Based Delivery Strategies to Lymphocytes. (2017) (38)
- Comprehensive and Systematic Analysis of the Immunocompatibility of Polyelectrolyte Capsules. (2017) (38)
- Advances in RNAi therapeutic delivery to leukocytes using lipid nanoparticles (2016) (35)
- Therapeutic mRNA delivery to leukocytes. (2019) (34)
- eIF3c: a potential therapeutic target for cancer. (2013) (33)
- Systemic siRNA delivery to leukocyte-implicated diseases (2009) (32)
- Grand challenges in modulating the immune response with RNAi nanomedicines. (2011) (32)
- Targeted lipid nanoparticles for RNA therapeutics and immunomodulation in leukocytes. (2020) (31)
- Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates alpha(4) integrins. (2008) (31)
- RNA nanomedicines: the next generation drugs? (2016) (30)
- Advanced Strategies in Immune Modulation of Cancer Using Lipid-Based Nanoparticles (2017) (29)
- RNA Inhibition Highlights Cyclin D1 as a Potential Therapeutic Target for Mantle Cell Lymphoma (2012) (29)
- Leukocyte-Specific siRNA Delivery Revealing IRF8 as a Potential Anti-Inflammatory Target. (2019) (29)
- Precision medicine--delivering the goods? (2014) (28)
- Conformation Sensitive Targeting of Lipid Nanoparticles for RNA Therapeutics (2021) (28)
- Harnessing nanomedicine for mucosal theranostics--a silver bullet at last? (2013) (28)
- Structural profiling and biological performance of phospholipid-hyaluronan functionalized single-walled carbon nanotubes. (2013) (27)
- Cationic Amphiphilic Drugs Boost the Lysosomal Escape of Small Nucleic Acid Therapeutics in a Nanocarrier-Dependent Manner. (2020) (26)
- Optimizing the biofabrication process of omentum-based scaffolds for engineering autologous tissues (2014) (25)
- Detection of intestinal inflammation by MicroPET imaging using a 64Cu‐labeled anti‐&bgr;7 integrin antibody (2010) (25)
- Induction of therapeutic gene silencing in leukocyte-implicated diseases by targeted and stabilized nanoparticles: a mini-review. (2010) (25)
- Assessing cellular toxicities in fibroblasts upon exposure to lipid-based nanoparticles: a high content analysis approach (2011) (24)
- Platelet mimicry: The emperor's new clothes? (2016) (22)
- Harnessing RNAi nanomedicine for precision therapy (2014) (22)
- Progress and challenges towards CRISPR/Cas clinical translation. (2020) (21)
- Engineering lymphocytes with RNAi. (2019) (20)
- Nanotechnology-based strategies against SARS-CoV-2 variants (2022) (19)
- Antibody-mediated delivery of siRNAs for anti-HIV therapy. (2011) (19)
- Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo (2021) (19)
- Liposomes and other assemblies as drugs and nano-drugs: from basic and translational research to the clinics. (2012) (18)
- Colitis ImmunoPET: Defining Target Cell Populations and Optimizing Pharmacokinetics (2015) (18)
- Metastability in lipid based particles exhibits temporally deterministic and controllable behavior (2015) (16)
- SNP Detection in mRNA in Living Cells Using Allele Specific FRET Probes (2013) (16)
- Serum chemokine network correlates with chemotherapy in non-small cell lung cancer. (2015) (16)
- Targeting central nervous system pathologies with nanomedicines (2018) (15)
- Immunomodulation of hematological malignancies using oligonucleotides based-nanomedicines. (2016) (15)
- An ovarian spheroid based tumor model that represents vascularized tumors and enables the investigation of nanomedicine therapeutics. (2020) (15)
- Liposomes, lipid biophysics, and sphingolipid research: from basic to translation research. (2012) (14)
- Enhanced bioavailability of polyaromatic hydrocarbons in the form of mucin complexes. (2011) (14)
- Investigation of pH-Responsiveness inside Lipid Nanoparticles for Parenteral mRNA Application Using Small-Angle X-ray Scattering. (2020) (14)
- The Human P-Glycoprotein Transporter Enhances the Type I Interferon Response to Listeria monocytogenes Infection (2015) (13)
- Nanotoxicity and the importance of being earnest. (2012) (13)
- Challenges in IBD Research: Novel Technologies. (2019) (13)
- ECM‐based macroporous sponges release essential factors to support the growth of hematopoietic cells (2017) (13)
- Dual‐Targeted Lipid Nanotherapeutic Boost for Chemo‐Immunotherapy of Cancer (2022) (12)
- Integrin-targeted nanoparticles for siRNA delivery. (2011) (12)
- Roadmap on nanomedicine (2020) (12)
- siRNA delivery: current trends and future perspectives. (2016) (11)
- Corrosion characteristics of plasma sprayed flyash–SiC and flyash–Al2O3 composite coatings on the Al-6061 alloy (2019) (11)
- Lipid Nanoparticle RBD-hFc mRNA Vaccine Protects hACE2 Transgenic Mice against a Lethal SARS-CoV-2 Infection. (2021) (11)
- Providing the full picture: a mandate for standardizing nanoparticle-based drug delivery. (2013) (11)
- Therapeutic Gene Silencing Using Targeted Lipid Nanoparticles in Metastatic Ovarian Cancer. (2021) (11)
- Handbook of Harnessing Biomaterials in Nanomedicine : Preparation, Toxicity, and Applications (2012) (10)
- Resveratrol Enhances mRNA and siRNA Lipid Nanoparticles Primary CLL Cell Transfection (2020) (10)
- Therapeutic inhibitory RNA in head and neck cancer via functional targeted lipid nanoparticles. (2021) (10)
- Nanodiamonds of Laser Synthesis for Biomedical Applications. (2015) (9)
- RNAi nanoparticles in the service of personalized medicine. (2009) (9)
- Molecular and Cellular Therapies: New challenges and opportunities (2013) (8)
- Targeting anthracycline-resistant tumor cells with synthetic aloe-emodin glycosides. (2011) (8)
- Hierarchical theranostic nanomedicine: MRI contrast agents as a physical vehicle anchor for high drug loading and triggered on-demand delivery. (2018) (8)
- Structural Characterization of the Drug Translocation Path of MRP1/ABCC1 (2014) (7)
- Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions * (7)
- RNA delivery with a human virus-like particle (2021) (6)
- Focus on RNA interference: from nanoformulations to in vivo delivery (2018) (6)
- Fe3O4 Nanoparticles and Paraffin Wax as Phase Change Materials Embedded in Polymer Matrixes for Temperature-Controlled Magnetic Hyperthermia (2021) (6)
- Delivery strategies of RNA therapeutics to leukocytes (2022) (6)
- Nanotechnology for the delivery of therapeutic nucleic acids (2013) (6)
- - Lipoplexes and Polyplexes: From Gene Delivery to Gene Expression (2013) (5)
- Recent Progress in Polymer Therapeutics as Nanomedicines (2012) (5)
- Systemic Modulation of Lymphocyte Subsets Using siRNAs Delivered via Targeted Lipid Nanoparticles. (2019) (5)
- Nanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility. (2022) (5)
- Integrin-targeted stabilized nanoparticles for an efficient delivery of siRNAs in vitro and in vivo. (2012) (5)
- Overcoming RNAi transduction in leukocytes using targeted and stabilized nanoparticles. (2010) (5)
- eIF 3 c : A potential therapeutic target for cancer (2013) (4)
- Polyethylene Glycol Polyester Block Copolymers: Biocompatible Carriers for Nanoparticulate Drug Delivery (2012) (4)
- IKAP/hELP1 down-regulation in neuroblastoma cells causes enhanced cell adhesion mediated by contactin overexpression (2010) (4)
- Dielectrophoretic characterization of cells in a stationary nanoliter droplet array with generated chemical gradients (2015) (4)
- Orchestrating a Symphony on a Single Conjugate: Aptamer Targeting, Gene Silencing, and Immunomodulation to Enhance Antitumor Response. (2017) (3)
- A tissue chamber chip for assessing nanoparticle mobility in the extravascular space (2019) (3)
- Cell specific delivery of modified mRNA expressing therapeutic proteins to leukocytes (2018) (3)
- Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (2019) (3)
- RNA interference-based therapeutics and diagnostics (2014) (3)
- Personalized Tissue Implants: Personalized Hydrogels for Engineering Diverse Fully Autologous Tissue Implants (Adv. Mater. 1/2019) (2019) (3)
- Zooming in on selectins in cancer (2016) (3)
- Correction: SNP Detection in mRNA in Living Cells Using Allele Specific FRET Probes (2013) (2)
- Dan Peer an Anti-Inflammatory Target Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D 1 as (2012) (2)
- Featuring the special issue guest editor: Dan Peer, Ph.D. (2014) (2)
- Polysaccharides as Nanomaterials for Therapeutics (2012) (2)
- A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs (2022) (2)
- Doxil® — The First FDA-Approved Nano-Drug: From an Idea to a Product (2012) (2)
- Polysaccharides as Building Blocks for Nanotherapeutics (2012) (1)
- A single-dose F1-based mRNA-LNP vaccine provides protection against the lethal plague bacterium (2023) (1)
- An Effective mRNA-LNP Vaccine Against the Lethal Plague Bacterium (2022) (1)
- Delivery strategies of RNA therapeutics for ex vivo and in vivo B-cell malignancies (2022) (1)
- Nanocarriers delivering RNAi to cancer cells: from challenge to cautious optimism (2009) (1)
- P181Artificial exosomes for post-ischemic vascular regeneration (2017) (1)
- Ionizable lipid nanoparticles are effective at penetrating the core of epithelial ovarian cancer spheroids (2019) (1)
- DDIS-03. HARNESSING siRNA NANOMEDICINE FOR THERAPEUTIC GENE SILENCING IN GLIOBLASTOMA (2017) (1)
- T.86. siRNA Delivery with Integrin LFA-1-targeted Nanoparticles Prevents HIV Infection in Humanized Mice (2009) (1)
- Publisher Correction: On the issue of transparency and reproducibility in nanomedicine (2019) (1)
- Harnessing RNAi-based nanomedicines for precision medicine (2015) (1)
- Dual‐Targeted Lipid Nanotherapeutic Boost for Chemo‐Immunotherapy of Cancer (Adv. Mater. 13/2022) (2022) (1)
- Themed issue on nanoparticles in biology. (2013) (1)
- Quantitative analysis of recombinant glucocerebrosidase brain delivery via lipid nanoparticles (2018) (1)
- Nanomedicine as an emerging platform for metastatic lung cancer therapy (2015) (0)
- Nanomedicines for Systemic Delivery of RNAi Therapeutics (2013) (0)
- Genome editing in cancer: Challenges and potential opportunities (2022) (0)
- Progress and challenges towards targeted delivery of cancer therapeutics (2018) (0)
- EnhancedBioavailabilityofPolyaromaticHydrocarbonsintheFormof Mucin Complexes (2011) (0)
- We detail the arsenal of nanocarriers and molecules available for selective tumour targeting , and emphasize the challenges in cancer treatment (2007) (0)
- A tissue chamber chip for assessing nanoparticle mobility in the extravascular space (2019) (0)
- Systemic siRNA delivery: A progress report (2009) (0)
- Science Journals — AAAS (2016) (0)
- Toxicity profiling of several common RNAi-based nanomedicines: a comparative study (2013) (0)
- Targeted nanomedicine: Lessons learned and future directions. (2023) (0)
- Abstract 130: Development of Bioinspired Synthetic Exosomes With Proangiogenic Potential (2019) (0)
- Analytical Study of Performance of a Centrifugal Pump for Different Operating Conditions (2017) (0)
- Future Outlook of Nanopharmacy: Challenges and Opportunities (2016) (0)
- Design of SARS-CoV-2 RBD mRNA Vaccine Using Novel Ionizable Lipids (2020) (0)
- Single-Chain Polymer Nanoparticles for Application in Nanomedicine (2012) (0)
- CRISPR editing in the lung with novel lipids. (2023) (0)
- Erratum: Gene Silencing in the Right Place at the Right Time (Molecular Therapy (2018) 26(11) (2539–2541), (S1525001618304945), (10.1016/j.ymthe.2018.10.005)) (2018) (0)
- Gene Silencing in the Right Place at the Right Time. (2018) (0)
- Theranostic nanoparticles for treatment of inflammatory disease and cancer (2016) (0)
- Identification of Cancer Cells in the Human Body by Anti-Telomerase Peptide Antibody: Towards the Isolation of Circulating Tumor Cells (2022) (0)
- SCIDOT-40. THERAPEUTIC GENOME EDITING AS A NOVEL TREATMENT FOR GBM (2019) (0)
- Development and Application of Conformation‐Selective Integrin Antibodies (2011) (0)
- RNA Delivery: A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes (Adv. Mater. 12/2020) (2020) (0)
- A lipid nanoparticle RBD-hFc mRNA vaccine protects hACE2 transgenic mice against lethal SARS-CoV-2 infection (2021) (0)
- NT-09CO-DELIVERY OF siRNA AND CHEMOTHERAPY; A NEW APPROACH FOR GBM TREATMENT USING A NANOCARRIERS SYSTEM (2014) (0)
- mRNA Vaccines: Using Tiny Particles to Fight Viruses (2023) (0)
- Sweet Fairytale: Carbohydrates as Backbones for Glyconanomedicine (2013) (0)
- Gene Silencing in the Right Place at the Right Time. (2018) (0)
- Dielectrophoretic characterization of cells in a stationary nanoliter droplet array with generated chemical gradients (2015) (0)
- Cationic lipids for nucleic acid delivery and preparation thereof (2017) (0)
- Reprogramming the lymphocyte axis for advanced immunotherapy. (2019) (0)
- Omics‐Based Nanopharmacy: Powerful Tools Toward Precision Medicine (2016) (0)
- Therapeutic gene silencing of CKAP5 leads to lethality in genetically unstable cancer cells (2023) (0)
- Revealing Cyclin D 1 as an Anti-Inflammatory Target Systemic Leukocyte-Directed siRNA Delivery (2008) (0)
- Targeting Cancer Using Nanocarriers (2016) (0)
- A Combinatorial Library of Lipid Nanoparticles for Cell Type-Specific mRNA Delivery. (2023) (0)
- Progress and challenges towards targeted delivery of cancer therapeutics you. Your (2018) (0)
- lipidated glycosaminoglycan particles and their use in drug delivery and gene therapy and diagnostic (2002) (0)
- Overcoming transport barriers using modified starch based nanoparticles and ultrasound application for gene silencing (2014) (0)
- Structural pro fi ling and biological performance of phospholipid – hyaluronan functionalized single-walled carbon nanotubes (2013) (0)
- Gene Silencing: Therapeutic Gene Silencing Using Targeted Lipid Nanoparticles in Metastatic Ovarian Cancer (Small 19/2021) (2021) (0)
- Vascular degeneration and restoration / A look at aortic stenosis from different angles 33 (0)
- RNA interference-based therapeutics and diagnostics (2013) (0)
- Computational Aspects in Gene Expression Analysis (2004) (0)
- The main challenge in the treatment of neurodegenerative diseases is to overcome the restrictive mechanism of the blood brain barrier and deliver therapeutic payloads to the brain . PERSPEC TIV E (2014) (0)
- Biomaterial-Based Particulate Drug Carriers (2012) (0)
- Radioimmunodetection of colitis using the Fab fragment of FIB504.64 (2013) (0)
- Manipulation of leukocytes using therapeutic rnai delivered by targeted and stabilized nanoparticles (2013) (0)
- Polysaccharides as building blocks for nanotherapeuticsw (2011) (0)
- The human P-glycoprotein Transporter enhances the 1 Type I Interferon Response to L . monocytogenes 2 Infection 3 4 5 (2015) (0)
- Radioimmunodetection of colitis using an antibody raised against integrin beta-7 (2009) (0)
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Dan Peer is affiliated with the following schools: