Danesh Moazed
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Danesh Moazedbiology Degrees
Biology
#10448
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Molecular Biology
#1518
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#1545
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Biology
Danesh Moazed's Degrees
- PhD Molecular Biology Stanford University
- Masters Biochemistry Stanford University
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Danesh Moazed's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- RNAi-Mediated Targeting of Heterochromatin by the RITS Complex (2004) (1257)
- Interaction of antibiotics with functional sites in 16S ribosomal RNA (1987) (1058)
- Heterochromatin and Epigenetic Control of Gene Expression (2003) (1018)
- RNA-mediated epigenetic regulation of gene expression (2015) (809)
- Small RNAs in transcriptional gene silencing and genome defence (2009) (787)
- Exit from Mitosis Is Triggered by Tem1-Dependent Release of the Protein Phosphatase Cdc14 from Nucleolar RENT Complex (1999) (760)
- Intermediate states in the movement of transfer RNA in the ribosome (1989) (730)
- Two RNAi Complexes, RITS and RDRC, Physically Interact and Localize to Noncoding Centromeric RNAs (2004) (577)
- Identification of a Class of Small Molecule Inhibitors of the Sirtuin Family of NAD-dependent Deacetylases by Phenotypic Screening* (2001) (516)
- Rapid chemical probing of conformation in 16 S ribosomal RNA and 30 S ribosomal subunits using primer extension. (1986) (461)
- Interaction of elongation factors EF-G and EF-Tu with a conserved loop in 23S RNA (1988) (458)
- Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites (1989) (443)
- Tethering RITS to a Nascent Transcript Initiates RNAi- and Heterochromatin-Dependent Gene Silencing (2006) (417)
- Structural analysis of RNA using chemical and enzymatic probing monitored by primer extension. (1988) (415)
- Net1, a Sir2-Associated Nucleolar Protein Required for rDNA Silencing and Nucleolar Integrity (1999) (414)
- An Enzymatic Activity in the Yeast Sir2 Protein that Is Essential for Gene Silencing (1999) (408)
- RITS acts in cis to promote RNA interference–mediated transcriptional and post-transcriptional silencing (2004) (406)
- Transfer RNA shields specific nucleotides in 16S ribosomal RNA from attack by chemical probes (1986) (388)
- Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA. (1987) (317)
- RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production. (2005) (315)
- Steps in Assembly of Silent Chromatin in Yeast: Sir3-Independent Binding of a Sir2/Sir4 Complex to Silencers and Role for Sir2-Dependent Deacetylation (2002) (304)
- Common themes in mechanisms of gene silencing. (2001) (283)
- Association of the Histone Methyltransferase Set2 with RNA Polymerase II Plays a Role in Transcription Elongation* (2002) (279)
- Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA. (1990) (265)
- Assembly of the SIR Complex and Its Regulation by O-Acetyl-ADP-Ribose, a Product of NAD-Dependent Histone Deacetylation (2005) (264)
- The nuclear envelope in genome organization, expression and stability (2010) (263)
- A Proteomic Strategy for Gaining Insights into Protein Sumoylation in Yeast*S (2005) (259)
- Association of the RENT complex with nontranscribed and coding regions of rDNA and a regional requirement for the replication fork block protein Fob1 in rDNA silencing. (2003) (254)
- Transcription and RNAi in heterochromatic gene silencing (2007) (252)
- RNAi-Dependent and -Independent RNA Turnover Mechanisms Contribute to Heterochromatic Gene Silencing (2007) (248)
- Epigenetic inheritance uncoupled from sequence-specific recruitment (2015) (237)
- A Deubiquitinating Enzyme Interacts with SIR4 and Regulates Silencing in S. cerevisiae (1996) (236)
- Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product. (2001) (236)
- Role for perinuclear chromosome tethering in maintenance of genome stability (2008) (226)
- Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3. (1997) (220)
- RNAi and heterochromatin assembly. (2015) (213)
- Mechanisms for the Inheritance of Chromatin States (2011) (205)
- HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms. (2008) (205)
- Interaction of antibiotics with A‐ and P‐site‐specific bases in 16S ribosomal RNA. (1991) (197)
- Sir2 Regulates Histone H3 Lysine 9 Methylation and Heterochromatin Assembly in Fission Yeast (2003) (196)
- TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway (2008) (187)
- Regulation of SIRT6 protein levels by nutrient availability (2008) (178)
- Dicer-Independent Primal RNAs Trigger RNAi and Heterochromatin Formation (2010) (174)
- Enzymatic activities of Sir2 and chromatin silencing. (2001) (170)
- Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer. (2006) (167)
- Role of the conserved Sir3-BAH domain in nucleosome binding and silent chromatin assembly. (2007) (164)
- A Cullin E3 Ubiquitin Ligase Complex Associates with Rik1 and the Clr4 Histone H3-K9 Methyltransferase and is Required for RNAi-Mediated Heterochromatin Formation (2005) (161)
- Specific protection of 16 S rRNA by translational initiation factors. (1995) (158)
- Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi. (2007) (157)
- RNAi‐directed assembly of heterochromatin in fission yeast (2005) (157)
- Mutations in 16S ribosomal RNA disrupt antibiotic–RNA interactions. (1989) (152)
- Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit. (2001) (145)
- Two different Argonaute complexes are required for siRNA generation and heterochromatin assembly in fission yeast (2007) (127)
- Maintenance of the engrailed expression pattern by Polycomb group genes in Drosophila. (1992) (125)
- Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA. (1991) (121)
- Mek1 Kinase Is Regulated To Suppress Double-Strand Break Repair between Sister Chromatids during Budding Yeast Meiosis (2007) (115)
- siRNA-mediated heterochromatin establishment requires HP1 and is associated with antisense transcription. (2008) (112)
- Nucleotides in 23S rRNA protected by the association of 30S and 50S ribosomal subunits. (1999) (110)
- S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription. (2007) (107)
- A Nonhistone Protein-Protein Interaction Required for Assembly of the SIR Complex and Silent Chromatin (2005) (98)
- DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation (2017) (97)
- Interconversion of active and inactive 30 S ribosomal subunits is accompanied by a conformational change in the decoding region of 16 S rRNA. (1986) (95)
- Reconstitution of heterochromatin-dependent transcriptional gene silencing. (2009) (92)
- Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex (2014) (87)
- Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription (2017) (87)
- Recombinational Repair within Heterochromatin Requires ATP-Dependent Chromatin Remodeling (2009) (85)
- Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation (2018) (79)
- Budding Yeast Silencing Complexes and Regulation of Sir2 Activity by Protein-Protein Interactions (2004) (78)
- Centromere Assembly and Propagation (2007) (75)
- Nucleotides in 16S rRNA protected by the association of 30S and 50S ribosomal subunits. (1999) (67)
- The Replication Fork Block Protein Fob1 Functions as a Negative Regulator of the FEAR Network (2004) (66)
- The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation. (2010) (65)
- Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3. (2003) (64)
- Sir3-Nucleosome Interactions in Spreading of Silent Chromatin in Saccharomyces cerevisiae (2008) (63)
- Determinants of heterochromatic siRNA biogenesis and function. (2014) (63)
- Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA (2013) (60)
- Transposon Silencing by piRNAs (2009) (55)
- A model for step-wise assembly of heterochromatin in yeast. (2008) (52)
- Automethylation-induced conformational switch in Clr4/Suv39h maintains epigenetic stability (2018) (51)
- Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance. (2019) (49)
- Studies on the mechanism of RNAi-dependent heterochromatin assembly. (2006) (47)
- Acetylated Histone Tail Peptides Induce Structural Rearrangements in the RSC Chromatin Remodeling Complex* (2007) (44)
- Regulation of Spo12 Phosphorylation and Its Essential Role in the FEAR Network (2009) (41)
- Small-RNA loading licenses Argonaute for assembly into a transcriptional silencing complex (2015) (40)
- Mechanisms of Gene Silencing (2001) (37)
- An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. (2009) (37)
- Autoregulation of convergent RNAi genes in fission yeast. (2011) (34)
- Epigenomics: A Roadmap, But to Where? (2008) (33)
- Studies on the Structure and Function of Ribosomal RNA (1986) (33)
- Affinity Pull-Down of Proteins Using Anti-FLAG M2 Agarose Beads. (2015) (28)
- Heterochromatic Gene Silencing by Activator Interference and a Transcription Elongation Barrier* (2013) (27)
- A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory (2016) (26)
- Heterochromatin assembly by interrupted Sir3 bridges across neighboring nucleosomes (2016) (23)
- Evolving Models of Heterochromatin: From Foci to Liquid Droplets. (2017) (21)
- New Alleles of SIR2 Define Cell-Cycle-Specific Silencing Functions (2006) (19)
- Rejoice—RNAi for Yeast (2009) (18)
- Affinity Purification of Protein Complexes Using TAP Tags. (2015) (17)
- Sister chromatid cohesion in silent chromatin: each sister to her own ring. (2006) (17)
- A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin (2020) (16)
- Distinct Functions of Argonaute Slicer in siRNA Maturation and Heterochromatin Formation. (2016) (15)
- Silencing repetitive DNA (2017) (14)
- Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose (2012) (14)
- Gene regulation: Expression and silencing coupled (2005) (13)
- Coimmunoprecipitation of proteins from yeast. (2014) (13)
- Protein- and immunoaffinity purification of multiprotein complexes. (2002) (13)
- Studies on the architecture and function of 16S rRNA. (1987) (12)
- Labeling and characterization of small RNAs associated with the RNA interference effector complex RITS. (2005) (12)
- A composite DNA element that functions as a maintainer required for epigenetic inheritance of heterochromatin. (2021) (11)
- Rixosomal RNA degradation contributes to silencing of Polycomb target genes (2022) (10)
- 22G-RNAs in transposon silencing and centromere function. (2009) (9)
- Clr4 specificity and catalytic activity beyond H3K9 methylation. (2017) (9)
- RNAi in fission yeast finds new targets and new ways of targeting at the nuclear periphery. (2012) (7)
- An RNA degradation complex required for silencing of Polycomb target genes (2019) (5)
- Recognition of acetylated proteins: lessons from an ancient family of enzymes. (2002) (5)
- Histone demethylation and timely DNA replication. (2010) (4)
- A piRNA to Remember (2012) (4)
- Studies on the structure and function of 16S ribosomal RNA using structure-specific chemical probes (1985) (2)
- Chromatin: A Tail of Repression (2013) (2)
- Evaluation of the Nucleolar Localization of the RENT Complex to Ribosomal DNA by Chromatin Immunoprecipitation Assays. (2017) (2)
- Faculty Opinions recommendation of Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state. (2013) (1)
- The BAH domain of Sir3 is the primary nucleosome binding domain in the SIR silencing complex (2007) (1)
- CSR-1 Slices a Balance (2016) (1)
- An RNA Degradation Complex Required for Spreading and Epigenetic Inheritance of Heterochromatin (2019) (1)
- Structure of the S. pombe Clr4 catalytic domain bound to SAH (2018) (0)
- Molecular Cell Previews 22 G-RNAs in Transposon Silencing and Centromere Function (0)
- Crystal structure of heterochromatin protein Sir3 in complex with a silenced yeast nucleosome (2013) (0)
- Cell nucleus. (2013) (0)
- Three rules for epigenetic inheritance of human Polycomb silencing (2023) (0)
- Regulation of Chromatin Structure and Aging by Sir2 (2003) (0)
- Faculty Opinions recommendation of Highly complementary target RNAs promote release of guide RNAs from human Argonaute2. (2013) (0)
- Faculty Opinions recommendation of A bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeast. (2013) (0)
- Author response: A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin (2020) (0)
- clamp complex recruited to the rDNA recombination enhancer Inhibition of homologous recombination by a cohesin-associated (2008) (0)
- Signals that Distinguish Noncoding RNA Scaffolds from mRNAs (2015) (0)
- Requirements for establishment and epigenetic stability of mammalian heterochromatin (2023) (0)
- Role of Non‐coding RNAs in Heterochromatin Formation (2008) (0)
- block protein Fob 1 in rDNA silencing regions of rDNA and a regional requirement for the replication fork Association of the RENT complex with nontranscribed and coding data (2003) (0)
- SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions. (2023) (0)
- Erratum: Structure of the coiled-coil dimerization motif of Sir4 and its interaction with Sir3 (Structure 11 (637-649)) (2004) (0)
- Chromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-ribose (2011) (0)
- Decision letter: S-phase-independent silencing establishment in Saccharomyces cerevisiae (2020) (0)
- Structure of the S. pombe Clr4 catalytic domain bound to SAM (2018) (0)
- Silencing repetitive DNA The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2017) (0)
- Faculty Opinions recommendation of CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors. (2013) (0)
- Hybrid States of tRNA During Translation (1993) (0)
- The SNARE-mediated vesicular transport pathway plays major roles in synaptic remodeling (2016) (0)
- Rixosomal RNA degradation contributes to silencing of Polycomb target genes (2022) (0)
- Crystal Structure of the Coiled-coil Dimerization Motif of Sir4 (2003) (0)
- Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability (2018) (0)
- Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation (2018) (0)
- Real-Time Quantitative PCR and Fluorescence In Situ Hybridization for Subcellular Localization of miRNAs in Neurons. (2022) (0)
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Danesh Moazed is affiliated with the following schools: