Daniel Francis Mcauley
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Daniel Francis Mcauley's Degrees
- PhD Immunology Stanford University
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Daniel Francis Mcauley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- COVID-19: consider cytokine storm syndromes and immunosuppression (2020) (7461)
- Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. (2016) (3097)
- Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 (2021) (1105)
- A minimal common outcome measure set for COVID-19 clinical research (2020) (939)
- An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome (2017) (906)
- Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1). (2011) (769)
- Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial. (2020) (583)
- Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 (2021) (508)
- Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 (2021) (485)
- Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine (2021) (439)
- The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index. (2014) (429)
- Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study (2017) (412)
- Mesenchymal Stromal Cells Modulate Macrophages in Clinically Relevant Lung Injury Models by Extracellular Vesicle Mitochondrial Transfer (2017) (409)
- Efficacy of the NVX-CoV2373 Covid-19 Vaccine Against the B.1.351 Variant (2021) (389)
- The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology (2016) (386)
- Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. (2018) (355)
- Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS (2016) (341)
- Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial. (2013) (320)
- Simvastatin in the acute respiratory distress syndrome. (2014) (298)
- Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial (2012) (290)
- Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis (2017) (268)
- Guidelines on the management of acute respiratory distress syndrome (2019) (262)
- The β-agonist lung injury trial (BALTI) : A randomized placebo-controlled clinical trial (2006) (252)
- Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. (2009) (248)
- The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial. (2006) (243)
- Respiratory follow-up of patients with COVID-19 pneumonia (2020) (230)
- Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis. (2016) (228)
- Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (2016) (225)
- Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. (2020) (218)
- Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study (2021) (201)
- Clinical trials in acute respiratory distress syndrome: challenges and opportunities. (2017) (188)
- A randomized clinical trial of hydroxymethylglutaryl- coenzyme a reductase inhibition for acute lung injury (The HARP Study). (2011) (187)
- Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury. (2006) (187)
- Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair (2011) (174)
- Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study (2018) (172)
- Clinically relevant concentrations of β2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury* (2004) (167)
- Guidelines on the selection of patients with lung cancer for surgery (2005) (160)
- Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial. (2022) (143)
- Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study (2020) (143)
- Predictors of mortality in acute lung injury during the era of lung protective ventilation (2008) (139)
- Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia (2014) (138)
- Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation. (2014) (137)
- Discrepancies between clinical and postmortem diagnoses in critically ill patients: an observational study (2003) (135)
- Extravascular lung water indexed to predicted body weight is a novel predictor of intensive care unit mortality in patients with acute lung injury* (2010) (134)
- Acute lung injury and the acute respiratory distress syndrome in Ireland: a prospective audit of epidemiology and management (2008) (133)
- Acute respiratory distress syndrome (2016) (129)
- Accuracy and precision of blood pressure determination with the Finapres: an overview using re-sampling statistics (1998) (126)
- Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2021) (123)
- Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-κB dependent mechanism (2009) (118)
- Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials. (2020) (118)
- Targeting Siglecs with a sialic acid–decorated nanoparticle abrogates inflammation (2015) (117)
- Do changes in pulse oximeter oxygen saturation predict equivalent changes in arterial oxygen saturation? (2003) (117)
- Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-Infected Cystic Fibrosis Lung Are Due to Neutrophil Elastase Degradation1 (2009) (115)
- Development of core competencies for an international training programme in intensive care medicine. The CoBaTrICE Collaboration (2006) (114)
- Pharmacological treatments in ARDS; a state-of-the-art update (2013) (112)
- Pathophysiology of pulmonary hypertension in acute lung injury. (2012) (111)
- Human models of acute lung injury (2011) (105)
- A national survey of the management of delirium in UK intensive care units. (2010) (102)
- Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury. (2014) (99)
- C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients. (2011) (96)
- Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis (2014) (94)
- Deresuscitation of Patients With Iatrogenic Fluid Overload Is Associated With Reduced Mortality in Critical Illness* (2018) (93)
- Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo (2011) (93)
- Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome (2009) (89)
- Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. (2013) (87)
- Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries (2018) (87)
- Major differences in ICU admissions during the first and second COVID-19 wave in Germany (2021) (86)
- Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study. (2017) (86)
- Decisional responsibility for mechanical ventilation and weaning: an international survey (2011) (83)
- Subphenotypes in critical care: translation into clinical practice. (2020) (81)
- Extracorporeal carbon dioxide removal for patients with acute respiratory failure secondary to the acute respiratory distress syndrome: a systematic review (2014) (80)
- Routine delirium monitoring in a UK critical care unit (2009) (79)
- Evidence for chemokine synergy during neutrophil migration in ARDS (2016) (79)
- Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome (2015) (78)
- Essential care of critical illness must not be forgotten in the COVID-19 pandemic (2020) (77)
- Statin use and risk of delirium in the critically ill. (2014) (76)
- Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis (2015) (76)
- Innate Lymphoid Cells Are the Predominant Source of IL-17A during the Early Pathogenesis of Acute Respiratory Distress Syndrome. (2016) (75)
- Respiratory viral infection: a potential “missing link” in the pathogenesis of COPD (2019) (71)
- Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review. (2015) (70)
- Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia (2014) (69)
- The beta agonist lung injury trial prevention. A randomized controlled trial. (2014) (68)
- In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury (2006) (68)
- Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients. (2013) (67)
- Bench-to-bedside review: β2-Agonists and the acute respiratory distress syndrome (2003) (66)
- miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production. (2014) (66)
- The effects of oral methionine and homocysteine on endothelial function (2001) (66)
- High-volume haemofiltration for sepsis in adults. (2017) (65)
- Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial. (2017) (64)
- Moral distress in end-of-life care in the intensive care unit. (2013) (63)
- Ventilator-associated pneumonia is characterized by excessive release of neutrophil proteases in the lung. (2012) (60)
- Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial. (2021) (59)
- Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis (2015) (59)
- Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children. (2013) (58)
- Differential effects of sustained inflation recruitment maneuvers on alveolar epithelial and lung endothelial injury* (2005) (58)
- Selenium in critical illness (2006) (58)
- Variation in Definition of Prolonged Mechanical Ventilation (2017) (57)
- How outcomes are defined in clinical trials of mechanically ventilated adults and children. (2014) (56)
- Statins and brain dysfunction: a hypothesis to reduce the burden of cognitive impairment in patients who are critically ill. (2011) (55)
- Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future. (2018) (55)
- Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury (2018) (55)
- Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial. (2017) (55)
- Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS (2020) (55)
- The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis (2018) (54)
- Effect of Protocolized Weaning With Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure: The Breathe Randomized Clinical Trial (2018) (53)
- Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation (2019) (53)
- The Naturally Occurring Host Defense Peptide, LL-37, and Its Truncated Mimetics KE-18 and KR-12 Have Selected Biocidal and Antibiofilm Activities Against Candida albicans, Staphylococcus aureus, and Escherichia coli In vitro (2017) (53)
- VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema (2005) (53)
- Redefining critical illness (2022) (52)
- Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2022) (52)
- Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome (2015) (52)
- Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization (2013) (51)
- Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation (2016) (50)
- Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study* (2019) (50)
- A Core Outcome Set for Critical Care Ventilation Trials (2013) (48)
- Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
- Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
- Emerging pharmacological therapies for ARDS: COVID-19 and beyond (2020) (47)
- Core Outcomes in Ventilation Trials (COVenT): protocol for a core outcome set using a Delphi survey with a nested randomised trial and observational cohort study (2015) (45)
- High-volume haemofiltration for sepsis. (2013) (44)
- Role of nonbronchoscopic lavage for investigating alveolar inflammation and permeability in acute respiratory distress syndrome (2006) (44)
- Mechanical Ventilation for ARDS During Extracorporeal Life Support: Research and Practice. (2019) (44)
- Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat (2011) (43)
- Beta-Agonist Lung injury TrIal-2 (BALTI-2): a multicentre, randomised, double-blind, placebo-controlled trial and economic evaluation of intravenous infusion of salbutamol versus placebo in patients with acute respiratory distress syndrome. (2013) (43)
- Statin therapy in critically-ill patients with severe sepsis: a review and meta-analysis of randomized clinical trials. (2015) (41)
- Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis (2018) (41)
- Treatment of Acute Lung Injury: Current and Emerging Pharmacological Therapies (2013) (41)
- Mechanical Ventilation in Adults with Acute Respiratory Distress Syndrome. Summary of the Experimental Evidence for the Clinical Practice Guideline (2017) (41)
- Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (the REVIVE trial) (2016) (40)
- Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models (2013) (40)
- An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial (2014) (39)
- An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19 (2021) (38)
- Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy — Achieving global consensus and visibility for cellular host-directed therapies (2020) (38)
- A national survey of the diagnosis and management of suspected ventilator-associated pneumonia (2014) (38)
- Human lipopolysaccharide models provide mechanistic and therapeutic insights into systemic and pulmonary inflammation (2020) (37)
- CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study. (2018) (37)
- Advancing precision medicine for acute respiratory distress syndrome (2021) (36)
- RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxygen, and standard care: A structured summary of a study protocol for a randomised controlled trial (2020) (35)
- Regulation of vascular endothelial growth factor bioactivity in patients with acute lung injury (2005) (34)
- Emerging drugs for treating the acute respiratory distress syndrome (2019) (34)
- Safety and tolerability of nonbronchoscopic lavage in ARDS. (2005) (34)
- Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial (2021) (34)
- Targeting Proteases in Cystic Fibrosis Lung Disease: Paradigms, Progress, and Potential. (2020) (34)
- Cystic fibrosis: basic science. (2000) (33)
- Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair (2019) (33)
- Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury (2013) (33)
- Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol (2013) (32)
- Homocysteine and endothelial vascular function (1998) (32)
- A novel subpopulation of monocyte-like cells in the human lung after lipopolysaccharide inhalation (2012) (32)
- Non-invasive respiratory support strategies in COVID-19 (2021) (32)
- A national clinical scenario‐based survey of clinicians' attitudes towards fresh frozen plasma transfusion for critically ill patients (2011) (31)
- Vasoconstriction to endogenous endothelin-1 is impaired in patients with type II diabetes mellitus. (2000) (31)
- Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching* (2017) (31)
- Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: protocol for a systematic review of quantitative and qualitative research (2016) (31)
- Respiratory Infections Cause the Release of Extracellular Vesicles: Implications in Exacerbation of Asthma/COPD (2014) (30)
- Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness. (2016) (30)
- Current practice in the management of new-onset atrial fibrillation in critically ill patients: a UK-wide survey (2017) (30)
- Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol (2011) (30)
- Tea tree oil (5%) body wash versus standard care (Johnson's Baby Softwash) to prevent colonization with methicillin-resistant Staphylococcus aureus in critically ill adults: a randomized controlled trial. (2013) (30)
- Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials (2017) (30)
- The Swine Flu Triage (SwiFT) study: development and ongoing refinement of a triage tool to provide regular information to guide immediate policy and practice for the use of critical care services during the H1N1 swine influenza pandemic. (2010) (29)
- Late mortality after acute hypoxic respiratory failure (2017) (29)
- Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database (2018) (29)
- Interventions for oropharyngeal dysphagia in acute and critical care: a systematic review and meta-analysis (2020) (29)
- Effect of Simvastatin on Physiological and Biological Outcomes in Patients Undergoing Esophagectomy: A Randomized Placebo-Controlled Trial (2014) (29)
- Impaired endothelium-dependent vasodilatation is a novel predictor of mortality in intensive care* (2011) (28)
- Role responsibilities in mechanical ventilation and weaning in pediatric intensive care units: a national survey. (2013) (27)
- IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo (2019) (27)
- 16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia (2014) (27)
- Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential (2020) (26)
- Fool’s gold? Why blinded trials are not always best (2020) (26)
- Airway Inflammation and Host Responses in the Era of CFTR Modulators (2020) (25)
- Peptoid Efficacy against Polymicrobial Biofilms Determined by Using Propidium Monoazide‐Modified Quantitative PCR (2016) (25)
- Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study (2019) (25)
- A randomized controlled trial of peripheral blood mononuclear cell depletion in experimental human lung inflammation. (2013) (25)
- Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance (2018) (24)
- Biological therapies in the acute respiratory distress syndrome (2014) (24)
- A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation. (2015) (23)
- Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial (2020) (23)
- Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial (2012) (23)
- Reliability of blood pressure determination with the Finapres with altered physiological states or pharmacodynamic conditions (1997) (23)
- Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report (2022) (23)
- Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis (2022) (23)
- Clara cell protein CC16. A new lung epithelial biomarker for acute lung injury. (2009) (23)
- Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials (2019) (22)
- Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study (2020) (22)
- Vasoconstriction to endothelin-1 is blunted in non-insulin-dependent diabetes: a dose-response study. (2000) (22)
- Levosimendan in septic shock in patients with biochemical evidence of cardiac dysfunction: a subgroup analysis of the LeoPARDS randomised trial (2019) (21)
- Observational cohort study examining apolipoprotein E status and preoperative neuropsychological performance as predictors of post-operative delirium in an older elective arthroplasty population (2017) (21)
- SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro (2014) (21)
- Diabetic macular oedema and diode subthreshold micropulse laser (DIAMONDS): study protocol for a randomised controlled trial (2019) (21)
- Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children. (2014) (21)
- Clinical trials in critical care: can a Bayesian approach enhance clinical and scientific decision making? (2020) (21)
- Fluid management and deresuscitation practices: A survey of critical care physicians (2020) (21)
- Moral distress in end-of-life decisions: A qualitative study of intensive care physicians. (2020) (21)
- Clinical review: Statins and trauma - a systematic review (2013) (20)
- A randomized controlled trial of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin-resistant Staphylococcus aureus (MRSA) in critically ill adults: research protocol (2008) (20)
- A stepwise approach to justify phase III randomized clinical trials and enhance the likelihood of a positive result (2010) (20)
- RAGE: a biomarker for acute lung injury (2008) (20)
- Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study (2020) (20)
- Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study (2020) (20)
- Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury (2013) (19)
- Acute lung failure. (2011) (19)
- Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial (2016) (19)
- Relationship between norepinephrine dose, tachycardia and outcome in septic shock: A multicentre evaluation. (2020) (19)
- Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial. (2021) (19)
- High-volume haemofiltration for sepsis (Protocol) (2009) (18)
- Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial (2015) (18)
- APOE Genotype and Alzheimer´s Disease (2000) (18)
- Forearm reactive hyperaemia is not mediated by nitric oxide in healthy volunteers. (1999) (18)
- Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. (1999) (17)
- Acute Respiratory Distress Syndrome Phenotypes and Identifying Treatable Traits. The Dawn of Personalized Medicine for ARDS. (2017) (17)
- Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models (2019) (17)
- SARS-CoV-2 environmental contamination from hospitalised patients with COVID-19 receiving aerosol-generating procedures (2021) (17)
- C 5 a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients (2011) (16)
- Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management (2022) (15)
- Promises and challenges of personalized medicine to guide ARDS therapy (2021) (15)
- Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury (2012) (15)
- Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. (2022) (15)
- Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury (2011) (15)
- Type XVIII collagen degradation products in acute lung injury (2009) (15)
- Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery (2019) (15)
- Translational research: what does it mean, what has it delivered and what might it deliver? (2011) (15)
- Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression (2021) (15)
- Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial (2021) (14)
- Interventions for oropharyngeal dysphagia in acute and critical care: a protocol for a systematic review and meta-analysis (2019) (14)
- Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Randomized Controlled Trial in Sheep (2020) (14)
- Targeting Candida albicans in dual-species biofilms with antifungal treatment reduces Staphylococcus aureus and MRSA in vitro (2021) (14)
- Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial (2017) (14)
- Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial (2021) (14)
- Influenza-related pneumonia. (2012) (14)
- Towards a biological definition of ARDS: are treatable traits the solution? (2022) (13)
- Prior colonisation with Candida species fails to guide empirical therapy for candidaemia in critically ill adults. (2010) (13)
- Individual patient data analysis of tidal volumes used in three large randomized control trials involving patients with acute respiratory distress syndrome (2017) (13)
- Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think? (2018) (13)
- Is There a Role for β-Adrenoceptor Agonists in the Management of Acute Lung Injury and the Acute Respiratory Distress Syndrome? (2005) (13)
- CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study. (2018) (13)
- Mesenchymal stem cells may ameliorate inflammation in an ex vivo model of extracorporeal membrane oxygenation (2019) (13)
- Effectiveness of a programme of exercise on physical function in survivors of critical illness following discharge from the ICU: study protocol for a randomised controlled trial (REVIVE) (2014) (13)
- A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung (2015) (13)
- The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study (2020) (12)
- The Impact of Aging in Acute Respiratory Distress Syndrome: A Clinical and Mechanistic Overview (2020) (12)
- Divide and conquer: identifying acute respiratory distress syndrome subphenotypes (2017) (12)
- Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial (2019) (12)
- Hyperhomocysteinaemia in young adults is not associated with impaired endothelial function. (2001) (12)
- Novel pulmonary biomarkers in the diagnosis of VAP (2010) (12)
- Mesenchymal stem cell therapy in acute lung injury: is it time for a clinical trial? (2012) (11)
- Apples and oranges: international comparisons of COVID-19 observational studies in ICUs (2020) (11)
- Sedation/drugs used in intensive care sedation (2015) (11)
- Nasal potential difference to detect Na+ channel dysfunction in acute lung injury. (2011) (11)
- A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis (2019) (11)
- New flow cytometric technique for the evaluation of circulating endothelial progenitor cell levels in various disease groups. (2006) (11)
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- A molecular analysis approach for biofilm quantification (2013) (0)
- Plasma Markers of Neurodegeneration Associated with Postoperative Delirium in an Older Elective Arthroplasty Population (2022) (0)
- Antioxidants for the Treatment of Endothelial Dysfunction in Critical Illness (2007) (0)
- Preoperative Cerebrospinal Fluid and Plasma Markers of Inflammation and Neurodegeneration Predict Mortality Eight Years Later in an Observational Cohort Study of Postoperative delirium in an Older Elective Arthroplasty Populatio (2022) (0)
- Cerebrospinal Fluid Markers of Neurodegeneration Associated with Postoperative Delirium in an Older Elective Arthroplasty Population (2022) (0)
- Publisher Correction: The effect of blood pressure on mortality following out‑of‑hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database (2023) (0)
- Divide and conquer: Identifying Acute Respiratory Distress Syndrome sub-phenotypes (2017) (0)
- SeptiFast assay: polymerase chain reaction set-up (2015) (0)
- STATIN THERAPY IN CRITICAL ILLNESS (2011) (0)
- The role of SOCS2 and SOCS3 in macrophage plasticity and inflammation (2010) (0)
- More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia (2020) (0)
- Mesenchymal Stromal Cells Use Extracellular Vesicle-Mediated Mitochondrial Transfer to Modulate Human Macrophage Phenotype Through Enhancement of Oxidative Phosphorylation in the In Vitro and In Vivo Models of the Acute Respiratory Distress Syndrome (2017) (0)
- Risk factors for acute organ failure in ICU patients with single organ (respiratory) dysfunction or failure: an international, prospective, cohort study (2012) (0)
- Mesenchymal stromal cells (MSC) anti-microbial effect in acute respiratory distress syndrome (ARDS) is mediated in part by enhanced alveolar macrophage phagocytosis through cell contact-dependent mitochondrial transfer leading to improved macrophage bioenergetics (2016) (0)
- Lung fluid balance and pulmonary edema in the acute respiratory distress syndrome: modulation by beta adrenergenic stimulation (2004) (0)
- Out with the old or better use of the old? A quest in sedation*. (2013) (0)
- American Thoracic Society meeting 2017. American Journal of Respiratory and Critical Care Medicine 2017;195:A7504: Mesenchymal Stromal Cells Use Extracellular Vesicle-Mediated Mitochondrial Transfer to Modulate Human Macrophage Phenotype Through Enhancement of Oxidative Phosphorylation in the In Vit (2017) (0)
- CSF Aβ42 CONCENTRATION INDEPENDENTLY PREDICTS POSTOPERATIVE DELIRIUM IN AN ELDERLY ELECTIVE ARTHROPLASTY POPULATION (2017) (0)
- Potential involvement of monoamine oxidase activity in delirium onset and SARS-COV2 infection (2020) (0)
- Impact of MRSA colonization at admission on length of stay and mortality for patients in the ICU (2008) (0)
- Potential involvement of monoamine oxidase activity in SARS-COV2 infection and delirium onset (2020) (0)
- Impact of a Fully Controlled Ventilation in the First Days of Ards: an Ancillary Analysis of The Lung Safe Study (2017) (0)
- A National Survey Of The Management Of Suspected Ventilator-Associated Pneumonia (2012) (0)
- Prospective Investigation of Markers of Elevated Delirium Risk (PRIMED Risk) study protocol: a prospective, observational cohort study investigating blood and cerebrospinal fluid biomarkers for delirium and cognitive dysfunction in older patients (2020) (0)
- SeptiFast assay: data analysis and reporting (2015) (0)
- Beta 2 antagonism in acute respiratory failure (2010) (0)
- Feasibility of Slow Continuous Ultrafiltration for Treatment of Fluid Overload in Critical Illness: In Vitro Investigation of Venous Access Options (0)
- Decreased levels of elafin in the lungs of patients with acute lung injury as a result of proteolytic cleavage by the proteasome (2012) (0)
- The Alveolar Macrophage and Acute Respiratory Distress Syndrome (2014) (0)
- Aspirin inhibits neutrophilic inflammation in experimental ALI (2016) (0)
- Vascular Responses to Endothelin-1 in Diabetes (1998) (0)
- Consultee declaration form (2015) (0)
- Discovery of novel metabolomic biomarkers of postoperative delirium in cerebrospinal fluid. (2018) (0)
- Significant plasma metabolite alterations in people over 65 going on to develop postoperative delirium. (2019) (0)
- TRPC6 inhibitor (BI 764198) to reduce risk and severity of ARDS due to COVID-19: a phase II randomised controlled trial (2023) (0)
- Comparison between mortality and airway colonisation versus noncolonisation with Candida species in critically ill adults (2008) (0)
- Respiratory Support in the Time of COVID-19. (2022) (0)
- Consultee information sheet (2015) (0)
- Prevention Of Pulmonary Inflammation And Cellular Injury By Simvastatin In A One Lung Ventilation Model Of ALI In Patients Undergoing Oesophagectomy (2012) (0)
- Pleural cavity exploitation in β-Agonist–treated ARDS patients [reply from authors] (2006) (0)
- CEREBROSPINAL FLUID/PLASMA ALBUMIN RATIO PREDICTS POSTOPERATIVE DELIRIUM IN AN OLDER ELECTIVE ORTHOPAEDIC POPULATION (2018) (0)
- transport in lung and airways Review: Role of aquaporin water channels in fluid Invited Lung Edema Clearance: 20 Years of Progress (2015) (0)
- European Respiratory Society International Congress 2017. European Respiratory Journal 2017 50: PA341; DOI: 10.1183/1393003.congress-2017.PA341: Effects of hypercapnic acidosis on the primary cells relevant to ARDS pathophysiology and the therapeutic potential of mesenchymal stem cells (2017) (0)
- A randomised trial of the effects on recruitment and retention of including a wet-ink signature and photograph in the patient invitation letter for a clinical trial: results from a Study Within a Trial (SWAT 3 and SWAT 53) (2022) (0)
- Effects of hypercapnic acidosis on the primary cells relevant to ARDS pathophysiology and the therapeutic potential of mesenchymal stem cells (2017) (0)
- ASpirin as a Treatment for Acute Respiratory Distress Syndrome – a multi-centre, randomised, double-blind, placebo-controlled trial (STAR): study protocol (2018) (0)
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