Daniel Francis Mcauley

Daniel Francis Mcauley's AcademicInfluence.com Rankings

Philosophy

#4398

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#6893

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#1858

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#2714

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Daniel Francis Mcauley

Biology

#5721

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#8268

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Immunology

#285

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#296

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Philosophy
Biology

Daniel Francis Mcauley's Degrees

PhD Immunology Stanford University
Doctorate Medicine Stanford University

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Daniel Francis Mcauley's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

COVID-19: consider cytokine storm syndromes and immunosuppression (2020) (7461)
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. (2016) (3097)
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 (2021) (1105)
A minimal common outcome measure set for COVID-19 clinical research (2020) (939)
An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome (2017) (906)
Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1). (2011) (769)
Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial. (2020) (583)
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 (2021) (508)
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 (2021) (485)
Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine (2021) (439)
The statistical significance of randomized controlled trial results is frequently fragile: a case for a Fragility Index. (2014) (429)
Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study (2017) (412)
Mesenchymal Stromal Cells Modulate Macrophages in Clinically Relevant Lung Injury Models by Extracellular Vesicle Mitochondrial Transfer (2017) (409)
Efficacy of the NVX-CoV2373 Covid-19 Vaccine Against the B.1.351 Variant (2021) (389)
The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology (2016) (386)
Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial. (2018) (355)
Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS (2016) (341)
Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial. (2013) (320)
Simvastatin in the acute respiratory distress syndrome. (2014) (298)
Effect of intravenous β-2 agonist treatment on clinical outcomes in acute respiratory distress syndrome (BALTI-2): a multicentre, randomised controlled trial (2012) (290)
Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis (2017) (268)
Guidelines on the management of acute respiratory distress syndrome (2019) (262)
The β-agonist lung injury trial (BALTI) : A randomized placebo-controlled clinical trial (2006) (252)
Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. (2009) (248)
The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial. (2006) (243)
Respiratory follow-up of patients with COVID-19 pneumonia (2020) (230)
Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis. (2016) (228)
Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (2016) (225)
Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. (2020) (218)
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study (2021) (201)
Clinical trials in acute respiratory distress syndrome: challenges and opportunities. (2017) (188)
A randomized clinical trial of hydroxymethylglutaryl- coenzyme a reductase inhibition for acute lung injury (The HARP Study). (2011) (187)
Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury. (2006) (187)
Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair (2011) (174)
Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study (2018) (172)
Clinically relevant concentrations of β2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury* (2004) (167)
Guidelines on the selection of patients with lung cancer for surgery (2005) (160)
Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial. (2022) (143)
Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study (2020) (143)
Predictors of mortality in acute lung injury during the era of lung protective ventilation (2008) (139)
Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia (2014) (138)
Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation. (2014) (137)
Discrepancies between clinical and postmortem diagnoses in critically ill patients: an observational study (2003) (135)
Extravascular lung water indexed to predicted body weight is a novel predictor of intensive care unit mortality in patients with acute lung injury* (2010) (134)
Acute lung injury and the acute respiratory distress syndrome in Ireland: a prospective audit of epidemiology and management (2008) (133)
Acute respiratory distress syndrome (2016) (129)
Accuracy and precision of blood pressure determination with the Finapres: an overview using re-sampling statistics (1998) (126)
Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2021) (123)
Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-κB dependent mechanism (2009) (118)
Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials. (2020) (118)
Targeting Siglecs with a sialic acid–decorated nanoparticle abrogates inflammation (2015) (117)
Do changes in pulse oximeter oxygen saturation predict equivalent changes in arterial oxygen saturation? (2003) (117)
Decreased Levels of Secretory Leucoprotease Inhibitor in the Pseudomonas-Infected Cystic Fibrosis Lung Are Due to Neutrophil Elastase Degradation1 (2009) (115)
Development of core competencies for an international training programme in intensive care medicine. The CoBaTrICE Collaboration (2006) (114)
Pharmacological treatments in ARDS; a state-of-the-art update (2013) (112)
Pathophysiology of pulmonary hypertension in acute lung injury. (2012) (111)
Human models of acute lung injury (2011) (105)
A national survey of the management of delirium in UK intensive care units. (2010) (102)
Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury. (2014) (99)
C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients. (2011) (96)
Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis (2014) (94)
Deresuscitation of Patients With Iatrogenic Fluid Overload Is Associated With Reduced Mortality in Critical Illness* (2018) (93)
Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo (2011) (93)
Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome (2009) (89)
Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. (2013) (87)
Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries (2018) (87)
Major differences in ICU admissions during the first and second COVID-19 wave in Germany (2021) (86)
Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study. (2017) (86)
Decisional responsibility for mechanical ventilation and weaning: an international survey (2011) (83)
Subphenotypes in critical care: translation into clinical practice. (2020) (81)
Extracorporeal carbon dioxide removal for patients with acute respiratory failure secondary to the acute respiratory distress syndrome: a systematic review (2014) (80)
Routine delirium monitoring in a UK critical care unit (2009) (79)
Evidence for chemokine synergy during neutrophil migration in ARDS (2016) (79)
Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome (2015) (78)
Essential care of critical illness must not be forgotten in the COVID-19 pandemic (2020) (77)
Statin use and risk of delirium in the critically ill. (2014) (76)
Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis (2015) (76)
Innate Lymphoid Cells Are the Predominant Source of IL-17A during the Early Pathogenesis of Acute Respiratory Distress Syndrome. (2016) (75)
Respiratory viral infection: a potential “missing link” in the pathogenesis of COPD (2019) (71)
Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review. (2015) (70)
Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia (2014) (69)
The beta agonist lung injury trial prevention. A randomized controlled trial. (2014) (68)
In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury (2006) (68)
Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients. (2013) (67)
Bench-to-bedside review: β2-Agonists and the acute respiratory distress syndrome (2003) (66)
miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production. (2014) (66)
The effects of oral methionine and homocysteine on endothelial function (2001) (66)
High-volume haemofiltration for sepsis in adults. (2017) (65)
Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial. (2017) (64)
Moral distress in end-of-life care in the intensive care unit. (2013) (63)
Ventilator-associated pneumonia is characterized by excessive release of neutrophil proteases in the lung. (2012) (60)
Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial. (2021) (59)
Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis (2015) (59)
Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children. (2013) (58)
Differential effects of sustained inflation recruitment maneuvers on alveolar epithelial and lung endothelial injury* (2005) (58)
Selenium in critical illness (2006) (58)
Variation in Definition of Prolonged Mechanical Ventilation (2017) (57)
How outcomes are defined in clinical trials of mechanically ventilated adults and children. (2014) (56)
Statins and brain dysfunction: a hypothesis to reduce the burden of cognitive impairment in patients who are critically ill. (2011) (55)
Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future. (2018) (55)
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury (2018) (55)
Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial. (2017) (55)
Mesenchymal stromal cell extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS (2020) (55)
The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis (2018) (54)
Effect of Protocolized Weaning With Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure: The Breathe Randomized Clinical Trial (2018) (53)
Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation (2019) (53)
The Naturally Occurring Host Defense Peptide, LL-37, and Its Truncated Mimetics KE-18 and KR-12 Have Selected Biocidal and Antibiofilm Activities Against Candida albicans, Staphylococcus aureus, and Escherichia coli In vitro (2017) (53)
VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema (2005) (53)
Redefining critical illness (2022) (52)
Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. (2022) (52)
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome (2015) (52)
Suppressors of Cytokine Signaling 2 and 3 Diametrically Control Macrophage Polarization (2013) (51)
Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation (2016) (50)
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study* (2019) (50)
A Core Outcome Set for Critical Care Ventilation Trials (2013) (48)
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial (2021) (48)
Emerging pharmacological therapies for ARDS: COVID-19 and beyond (2020) (47)
Core Outcomes in Ventilation Trials (COVenT): protocol for a core outcome set using a Delphi survey with a nested randomised trial and observational cohort study (2015) (45)
High-volume haemofiltration for sepsis. (2013) (44)
Role of nonbronchoscopic lavage for investigating alveolar inflammation and permeability in acute respiratory distress syndrome (2006) (44)
Mechanical Ventilation for ARDS During Extracorporeal Life Support: Research and Practice. (2019) (44)
Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat (2011) (43)
Beta-Agonist Lung injury TrIal-2 (BALTI-2): a multicentre, randomised, double-blind, placebo-controlled trial and economic evaluation of intravenous infusion of salbutamol versus placebo in patients with acute respiratory distress syndrome. (2013) (43)
Statin therapy in critically-ill patients with severe sepsis: a review and meta-analysis of randomized clinical trials. (2015) (41)
Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis (2018) (41)
Treatment of Acute Lung Injury: Current and Emerging Pharmacological Therapies (2013) (41)
Mechanical Ventilation in Adults with Acute Respiratory Distress Syndrome. Summary of the Experimental Evidence for the Clinical Practice Guideline (2017) (41)
Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (the REVIVE trial) (2016) (40)
Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models (2013) (40)
An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial (2014) (39)
An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19 (2021) (38)
Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy — Achieving global consensus and visibility for cellular host-directed therapies (2020) (38)
A national survey of the diagnosis and management of suspected ventilator-associated pneumonia (2014) (38)
Human lipopolysaccharide models provide mechanistic and therapeutic insights into systemic and pulmonary inflammation (2020) (37)
CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study. (2018) (37)
Advancing precision medicine for acute respiratory distress syndrome (2021) (36)
RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxygen, and standard care: A structured summary of a study protocol for a randomised controlled trial (2020) (35)
Regulation of vascular endothelial growth factor bioactivity in patients with acute lung injury (2005) (34)
Emerging drugs for treating the acute respiratory distress syndrome (2019) (34)
Safety and tolerability of nonbronchoscopic lavage in ARDS. (2005) (34)
Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial (2021) (34)
Targeting Proteases in Cystic Fibrosis Lung Disease: Paradigms, Progress, and Potential. (2020) (34)
Cystic fibrosis: basic science. (2000) (33)
Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair (2019) (33)
Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury (2013) (33)
Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol (2013) (32)
Homocysteine and endothelial vascular function (1998) (32)
A novel subpopulation of monocyte-like cells in the human lung after lipopolysaccharide inhalation (2012) (32)
Non-invasive respiratory support strategies in COVID-19 (2021) (32)
A national clinical scenario‐based survey of clinicians' attitudes towards fresh frozen plasma transfusion for critically ill patients (2011) (31)
Vasoconstriction to endogenous endothelin-1 is impaired in patients with type II diabetes mellitus. (2000) (31)
Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching* (2017) (31)
Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: protocol for a systematic review of quantitative and qualitative research (2016) (31)
Respiratory Infections Cause the Release of Extracellular Vesicles: Implications in Exacerbation of Asthma/COPD (2014) (30)
Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness. (2016) (30)
Current practice in the management of new-onset atrial fibrillation in critically ill patients: a UK-wide survey (2017) (30)
Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol (2011) (30)
Tea tree oil (5%) body wash versus standard care (Johnson's Baby Softwash) to prevent colonization with methicillin-resistant Staphylococcus aureus in critically ill adults: a randomized controlled trial. (2013) (30)
Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials (2017) (30)
The Swine Flu Triage (SwiFT) study: development and ongoing refinement of a triage tool to provide regular information to guide immediate policy and practice for the use of critical care services during the H1N1 swine influenza pandemic. (2010) (29)
Late mortality after acute hypoxic respiratory failure (2017) (29)
Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database (2018) (29)
Interventions for oropharyngeal dysphagia in acute and critical care: a systematic review and meta-analysis (2020) (29)
Effect of Simvastatin on Physiological and Biological Outcomes in Patients Undergoing Esophagectomy: A Randomized Placebo-Controlled Trial (2014) (29)
Impaired endothelium-dependent vasodilatation is a novel predictor of mortality in intensive care* (2011) (28)
Role responsibilities in mechanical ventilation and weaning in pediatric intensive care units: a national survey. (2013) (27)
IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo (2019) (27)
16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia (2014) (27)
Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential (2020) (26)
Fool’s gold? Why blinded trials are not always best (2020) (26)
Airway Inflammation and Host Responses in the Era of CFTR Modulators (2020) (25)
Peptoid Efficacy against Polymicrobial Biofilms Determined by Using Propidium Monoazide‐Modified Quantitative PCR (2016) (25)
Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study (2019) (25)
A randomized controlled trial of peripheral blood mononuclear cell depletion in experimental human lung inflammation. (2013) (25)
Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance (2018) (24)
Biological therapies in the acute respiratory distress syndrome (2014) (24)
A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation. (2015) (23)
Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration in COVID-19 (REALIST-COVID-19): A structured summary of a study protocol for a randomised, controlled trial (2020) (23)
Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute lung injury to Reduce Pulmonary dysfunction (HARP-2) trial: study protocol for a randomized controlled trial (2012) (23)
Reliability of blood pressure determination with the Finapres with altered physiological states or pharmacodynamic conditions (1997) (23)
Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report (2022) (23)
Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis (2022) (23)
Clara cell protein CC16. A new lung epithelial biomarker for acute lung injury. (2009) (23)
Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials (2019) (22)
Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study (2020) (22)
Vasoconstriction to endothelin-1 is blunted in non-insulin-dependent diabetes: a dose-response study. (2000) (22)
Levosimendan in septic shock in patients with biochemical evidence of cardiac dysfunction: a subgroup analysis of the LeoPARDS randomised trial (2019) (21)
Observational cohort study examining apolipoprotein E status and preoperative neuropsychological performance as predictors of post-operative delirium in an older elective arthroplasty population (2017) (21)
SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro (2014) (21)
Diabetic macular oedema and diode subthreshold micropulse laser (DIAMONDS): study protocol for a randomised controlled trial (2019) (21)
Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children. (2014) (21)
Clinical trials in critical care: can a Bayesian approach enhance clinical and scientific decision making? (2020) (21)
Fluid management and deresuscitation practices: A survey of critical care physicians (2020) (21)
Moral distress in end-of-life decisions: A qualitative study of intensive care physicians. (2020) (21)
Clinical review: Statins and trauma - a systematic review (2013) (20)
A randomized controlled trial of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin-resistant Staphylococcus aureus (MRSA) in critically ill adults: research protocol (2008) (20)
A stepwise approach to justify phase III randomized clinical trials and enhance the likelihood of a positive result (2010) (20)
RAGE: a biomarker for acute lung injury (2008) (20)
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study (2020) (20)
Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study (2020) (20)
Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury (2013) (19)
Acute lung failure. (2011) (19)
Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial (2016) (19)
Relationship between norepinephrine dose, tachycardia and outcome in septic shock: A multicentre evaluation. (2020) (19)
Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units: A Randomized Clinical Trial. (2021) (19)
High-volume haemofiltration for sepsis (Protocol) (2009) (18)
Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial (2015) (18)
APOE Genotype and Alzheimer´s Disease (2000) (18)
Forearm reactive hyperaemia is not mediated by nitric oxide in healthy volunteers. (1999) (18)
Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. (1999) (17)
Acute Respiratory Distress Syndrome Phenotypes and Identifying Treatable Traits. The Dawn of Personalized Medicine for ARDS. (2017) (17)
Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models (2019) (17)
SARS-CoV-2 environmental contamination from hospitalised patients with COVID-19 receiving aerosol-generating procedures (2021) (17)
C 5 a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients (2011) (16)
Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management (2022) (15)
Promises and challenges of personalized medicine to guide ARDS therapy (2021) (15)
Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury (2012) (15)
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. (2022) (15)
Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury (2011) (15)
Type XVIII collagen degradation products in acute lung injury (2009) (15)
Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery (2019) (15)
Translational research: what does it mean, what has it delivered and what might it deliver? (2011) (15)
Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression (2021) (15)
Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) randomised clinical trial (2021) (14)
Interventions for oropharyngeal dysphagia in acute and critical care: a protocol for a systematic review and meta-analysis (2019) (14)
Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome. A Randomized Controlled Trial in Sheep (2020) (14)
Targeting Candida albicans in dual-species biofilms with antifungal treatment reduces Staphylococcus aureus and MRSA in vitro (2021) (14)
Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial (2017) (14)
Repair of acute respiratory distress syndrome by stromal cell administration (REALIST) trial: A phase 1 trial (2021) (14)
Influenza-related pneumonia. (2012) (14)
Towards a biological definition of ARDS: are treatable traits the solution? (2022) (13)
Prior colonisation with Candida species fails to guide empirical therapy for candidaemia in critically ill adults. (2010) (13)
Individual patient data analysis of tidal volumes used in three large randomized control trials involving patients with acute respiratory distress syndrome (2017) (13)
Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think? (2018) (13)
Is There a Role for β-Adrenoceptor Agonists in the Management of Acute Lung Injury and the Acute Respiratory Distress Syndrome? (2005) (13)
CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study. (2018) (13)
Mesenchymal stem cells may ameliorate inflammation in an ex vivo model of extracorporeal membrane oxygenation (2019) (13)
Effectiveness of a programme of exercise on physical function in survivors of critical illness following discharge from the ICU: study protocol for a randomised controlled trial (REVIVE) (2014) (13)
A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung (2015) (13)
The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study (2020) (12)
The Impact of Aging in Acute Respiratory Distress Syndrome: A Clinical and Mechanistic Overview (2020) (12)
Divide and conquer: identifying acute respiratory distress syndrome subphenotypes (2017) (12)
Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial (2019) (12)
Hyperhomocysteinaemia in young adults is not associated with impaired endothelial function. (2001) (12)
Novel pulmonary biomarkers in the diagnosis of VAP (2010) (12)
Mesenchymal stem cell therapy in acute lung injury: is it time for a clinical trial? (2012) (11)
Apples and oranges: international comparisons of COVID-19 observational studies in ICUs (2020) (11)
Sedation/drugs used in intensive care sedation (2015) (11)
Nasal potential difference to detect Na+ channel dysfunction in acute lung injury. (2011) (11)
A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis (2019) (11)
New flow cytometric technique for the evaluation of circulating endothelial progenitor cell levels in various disease groups. (2006) (11)
Fluid strategies and outcomes in patients with acute respiratory distress syndrome, systemic inflammatory response syndrome and sepsis: a protocol for a systematic review and meta-analysis (2015) (10)
RAND appropriateness panel to determine the applicability of UK guidelines on the management of acute respiratory distress syndrome (ARDS) and other strategies in the context of the COVID-19 pandemic (2021) (10)
Statins in patients with sepsis and ARDS: is it over? We are not sure (2017) (10)
The effect on endothelial function of vitamin C during methionine induced hyperhomocysteinaemia (2001) (10)
Death in hospital following ICU discharge: insights from the LUNG SAFE study (2020) (9)
Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis (2020) (9)
Potential Mechanisms by which Statins Modulate the Development of Acute Lung Injury (2007) (9)
Delving beneath the surface of hyperinflammation in COVID-19 (2020) (9)
Comparison of machine learning clustering algorithms for detecting heterogeneity of treatment effect in acute respiratory distress syndrome: A secondary analysis of three randomised controlled trials (2021) (9)
Prolonged glucocorticoid treatment in acute respiratory distress syndrome – Authors' reply (2017) (9)
Effect of a single dose of etomidate on adrenal function in patients with trauma (2005) (9)
Pulmonary Aspergillosis in Patients with Suspected Ventilator-associated Pneumonia in UK Intensive Care Units. (2020) (9)
Is there a need for emerging drugs for the acute respiratory distress syndrome? (2014) (8)
Simvastatin pre-treatment improves survival and mitochondrial function in a 3-day fluid-resuscitated rat model of sepsis. (2017) (8)
Human mesenchymal stem cells (MSC) modulate alveolar macrophage polarization in vivo and in vitro. (2014) (8)
A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial (2019) (8)
Hot off the breath: the 2009 H1N1 flu pandemic may be gone but should not be forgotten (2010) (8)
Combined Mesenchymal Stromal Cell Therapy and ECMO in ARDS: A Controlled Experimental Study in Sheep. (2020) (8)
Stem cells for respiratory failure (2015) (8)
Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT (2018) (8)
Hyperhomocysteinaemia in young adults is not associated with impaired endothelial function (2001) (8)
Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study (2012) (7)
Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial (2022) (7)
Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT. (2019) (7)
Delirium in COVID-19: can we make the unknowns knowns? (2021) (7)
Characterizing preclinical sub‐phenotypic models of acute respiratory distress syndrome: An experimental ovine study (2021) (7)
Results Of The HARP Study: A Randomized Double Blind Phase II Trial Of 80mg Simvastatin In Acute Lung Injury (2010) (7)
Secreted Extracellular Cyclophilin A is a Novel Mediator of Ventilator Induced Lung Injury. (2021) (7)
Corticosteroids in acute respiratory distress syndrome: a step forward, but more evidence is needed. (2020) (7)
A Role for β2 Agonists in ARDS — The Question Remains Unanswered (2009) (6)
Is there a role for beta-adrenoceptor agonists in the management of acute lung injury and the acute respiratory distress syndrome? (2005) (6)
No Evidence of Endothelial Dysfunction in Patients with Alzheimer’s Disease (2000) (6)
Acute Respiratory Distress Syndrome Subphenotypes beyond the Syndrome: A Step toward Treatable Traits? (2021) (6)
Pro: β-agonists in acute lung injury--the end of the story? (2011) (6)
A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair (2015) (5)
Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT (2018) (5)
Pharmacological Therapy for Acute Lung Injury (2010) (5)
A United Kingdom Register study of in-hospital outcomes of patients receiving extracorporeal carbon dioxide removal (2018) (5)
Cathepsin S Contributes to Lung Inflammation in Acute Respiratory Distress Syndrome. (2022) (5)
Reciting the months of the year backwards: what is a 'normal' score? (2015) (5)
Bradykinin infusion in chronic cardiac failure and the effects of captopril (2001) (5)
Geoeconomic variations in epidemiology, ventilation management, and outcomes in invasively ventilated intensive care unit patients without acute respiratory distress syndrome: a pooled analysis of four observational studies (2021) (5)
Aspirin as a Treatment for Acute Respiratory Distress Syndrome: a randomised placebo controlled clinical trial. (2021) (5)
Oral health care for the critically ill: a narrative review (2021) (4)
Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial (2018) (4)
Protocol for a systematic review and network meta-analysis of the management of new onset atrial fibrillation in critically unwell adult patients (2019) (4)
Pharmacological treatments in ARDS (2013) (4)
Characterisation of eppin function: expression and activity in the lung (2017) (4)
Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients (2022) (4)
Academic Medicine – revolution, evolution or extinction? (2014) (4)
Matrix metalloproteinases: a potential role in the pathogensis of ARDS (2004) (4)
Guideline : Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome (2017) (4)
Mucoactive agent use in adult UK Critical Care Units: a survey of health care professionals’ perception, pharmacists’ description of practice, and point prevalence of mucoactive use in invasively mechanically ventilated patients (2020) (4)
Forearm endothelium-dependent vascular responses and the potassium-ATP channel. (2003) (4)
Airway clearance techniques and use of mucoactive agents for adult critically ill patients with acute respiratory failure: a qualitative study exploring UK physiotherapy practice. (2020) (4)
Consistent Ards Endotypes Are Identified Using Minimal Data From A United Kingdom Clinical Trial (2017) (4)
Statin therapy in critical illness: an international survey of intensive care physicians’ opinions, attitudes and practice (2012) (4)
Statins and sepsis: potential benefit but more unanswered questions. (2013) (4)
Noninvasive Respiratory Strategies and Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure Due to COVID-19-Reply. (2022) (4)
A nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury: A randomised, placebo-controlled pilot study (2020) (4)
Management of new onset atrial fibrillation in critically unwell adult patients: a systematic review and narrative synthesis (2021) (4)
Accuracy of LightCycler SeptiFast real-time polymerase chain reaction for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis (2015) (3)
Parenteral thiamine for prevention and treatment of delirium in critically ill adults: a systematic review protocol (2020) (3)
COVID-19–related Acute Respiratory Distress Syndrome Subphenotypes and Differential Response to Corticosteroids: Time for More Precision? (2021) (3)
Physical training and endothelial function in patients with chronic heart failure. (1996) (3)
Phagocyte priming as a prognostic indicator in the intensive care unit. (2003) (3)
Clinical trial design in prevention and treatment of acute respiratory distress syndrome. (2014) (3)
Mucoactive agents for acute respiratory failure in the critically ill: a systematic review and meta-analysis (2020) (3)
Search strategy for the systematic review (2015) (3)
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions (2022) (3)
Innate Lymphoid Cells are the Predominant Source of Interleukin-17A During the Early Pathogenesis of Acute Respiratory Distress Syndrome (2015) (3)
Comparing regression and neural network techniques for personalized predictive analytics to promote lung protective ventilation in Intensive Care Units (2020) (3)
Epidemiology and treatment of left ventricular hypertrophy in the elderly. (1999) (3)
Methods and assessment (2019) (3)
Comment on “Statin administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury” (2009) (3)
Helium-oxygen reduces the production of carbon dioxide during weaning from mechanical ventilation (2010) (3)
S102 KGF enhances pulmonary production of pro-epithelial repair factors in a human in vivo model of acute lung injury (2010) (3)
Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) - a pilot randomised controlled trial of conservative fluid administration and deresuscitation in critical illness: study protocol (2018) (3)
Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs (2021) (3)
Retraction notice to: Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. (2014) (3)
Hyperoxaemia and hypoxaemia are associated with harm in patients with ARDS (2021) (2)
Benefits of statins in the critically ill: promising but not proven. (2011) (2)
Using the TIDieR checklist to describe the intervention of the Sedation and Weaning in Children (SANDWICH) trial. (2022) (2)
The impact of a PCR assay for candidemia on antifungal drug prescribing in critical care: an interrupted time series pilot study. (2010) (2)
Does MMP-12 play a role in human lung fibrosis? (2008) (2)
Repair of acute respiratory distress syndrome by stromal cell administration (REALIST): a structured study protocol for an open-label dose-escalation phase 1 trial followed by a randomised, triple-blind, allocation concealed, placebo-controlled phase 2 trial (2022) (2)
The REVIVE study: A randomised controlled trial of the effect of a programme of exercise on physical function in survivors of critical illness after discharge from the intensive care unit (2015) (2)
Study into the reversal of septic shock with landiolol (beta blockade): STRESS-L Study protocol for a randomised trial (2021) (2)
Development and Validation of Parsimonious Algorithms to Classify ARDS Phenotypes: Secondary Analyses of Randomised Controlled Trials (2019) (2)
ESICM LIVES 2016: part two (2016) (2)
KGF Enhances The Pulmonary Production Of Epithelial Repair Factors Following Endotoxin Induced Lung Inflammation And Injury In Human Volunteers (2011) (2)
Do non-ventilatory strategies for acute lung injury and the acute respiratory distress syndrome work? (2010) (2)
ESICM LIVES 2016: part one (2016) (2)
Intensive care for the adult population in Ireland: a multicentre study of intensive care population demographics. The Irish Critical Care Trials Group (2008) (2)
Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation Effect on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure-Reply. (2022) (2)
ESICM LIVES 2016: part one (2016) (2)
Cytokine adsorption during ECMO for COVID-19-related ARDS (2021) (2)
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial (2022) (2)
Proceedings of the ISCT scientific signature series symposium, "sdvances in cell and gene therapies for lung diseases and critical illnesses": International society for cell & gene therapies, burlington VT, US, July 16, 2021. (2022) (2)
UK survey of doctors' views on mechanical ventilation and weaning role responsibilities (2010) (2)
The role of Tregs in controlling IL-17A in a model of LPS-induced lung injury (2012) (2)
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial (2022) (2)
Will Not Breathing on Extracorporeal Membrane Oxygenation Help One Survive Acute Respiratory Distress Syndrome? (2020) (2)
Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study (2017) (2)
Where next for cell-based therapy in ARDS (2018) (2)
The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database (2023) (1)
A randomised, placebo-controlled pilot study of a nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury. (2020) (1)
The future of acute and emergency care (2021) (1)
Participant consent form: recovered capacity (2015) (1)
Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis (2022) (1)
Comparison between mortality and airway colonization vs noncolonization with Candida species in critically ill adults. (2009) (1)
Comparing Regression and Neural Network techniques for personalised predictive analytics to promote lung protective We repeated this process for all points in the time series, for each patient and report the RMSE value per method.ventilation in Intensive Care Units (2020) (1)
Accuracy of LightCycler Septi F ast for the detection and identification of pathogens in the blood of patients with suspected sepsis : a systematic review and meta-analysis (2017) (1)
Randomised controlled trial and process evaluation of biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (2019) (1)
Clinical diagnostic accuracy study of rapid detection of sepsis-related health-care-associated bloodstream infection in intensive care using SeptiFast multipathogen real-time polymerase chain reaction technology (2015) (1)
Title Unexpected role for adaptive αβTh 17 cells in acute respiratory distress syndrome (2015) (1)
Transepithelial nasal potential difference in patients with, and at risk of acute respiratory distress syndrome (2021) (1)
What is the score with mortality predictions in acute lung injury? (2008) (1)
Erratum to: Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction – a randomised placebo-controlled trial (KARE): study protocol (2017) (1)
The EASI-SWITCH trial: Early switch to oral antibiotic therapy in patients with low risk neutropenic sepsis. (2016) (1)
Salbutamol drives upregulated MMP-9 activity in the alveolar space in acute respiratory distress syndrome (2007) (1)
Determinants of Effect of Extracorporeal CO 2 Removal in Hypoxemic Respiratory Failure (2023) (1)
The National Institute for Health Research Critical Care Research Priority Setting Survey 2018 (2020) (1)
S104 Monocyte influx accompanies the early neutrophilic inflammation seen in bronchoalveolar lavage fluid following lipopolysaccharide inhalation (2010) (1)
The use of prone ventilation in acute lung injury and acute respiratory distress syndrome (2001) (1)
ARDS Subphenotypes Beyond the Syndrome: A Step Towards Treatable Traits? (2021) (1)
The association between time of in hospital cardiac arrest and mortality; a retrospective analysis of two UK databases. (2023) (1)
The Use of Beta 2-Agonists for the Treatment of Acute Respiratory Distress Syndrome (2013) (1)
Combined MSC therapy and ECMO in experimental ARDS (2020) (1)
Erratum to: ‘Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial’ (2016) (1)
P014 SELENIUM DECREASES LIPID PEROXIDATION IN CRITICALLY-ILL PATIENTS WITH SUB-ARACHNOID HAEMORRHAGE (2009) (1)
Transepithelial Nasal Potential Difference Measurement Predicts The Development Of Acute Lung Injury (2012) (1)
Sedation and Ventilator Liberation Protocol vs Usual Care and Duration of Invasive Ventilation in Pediatric Intensive Care Units-Reply. (2021) (1)
American Thoracic Society Meeting 2016.: Mitochondrial Transfer Via Tunnelling Nanotubes (TNT) Is a Novel Mechanism by Which Mesenchymal Stromal Cells Enhance Macrophage Phagocytosis in In Vivo Models of Acute Lung Injury (2016) (1)
S52 The role of the Receptor for Advanced End Products (RAGE) in Acute Lung Injury (ALI) (2010) (1)
Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial (2022) (1)
Standards for the reporting of diagnostic accuracy studies checklist for reporting of studies of diagnostic accuracy (2015) (1)
WS9.5 CF epithelial cells are a source of pulmonary cathepsin S via increased IRF-1 (2012) (1)
Title : Accuracy of LightCycler ( R ) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis : a systematic review protocol (1)
Mechanical ventilation in adults with acute respiratory distress syndrome: An official clinical guideline of American Thoracic Society/European Society of Intensive Care medicine/Society of Critical care medicine (2018) (1)
Final study protocol (2013) (1)
Reflections on the Clinical Learning Points from the the Royal London Hospital Intensive Care Unit following July 7th 2005 Terrorist Attacks (2006) (1)
Assessing the quantity of pulmonary edema in critically ill children (2010) (1)
Elevated ferritin is associated with systemic inflammation, inflammasome activation and mortality in Acute Respiratory Distress Syndrome (ARDS) (2022) (1)
Statins exposure and delirium risk: a winning association?*. (2014) (1)
Human Mesenchymal Stem Cells Promote M2 Macrophage Polarization In Both In Vivo And In Vitro Models Of ARDS (2014) (1)
Clinical review: Statins and trauma-a systematic (2013) (1)
Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial. (2023) (1)
Title : How outcomes are defined in clinical trials of mechanically ventilated adults and children 2 (2015) (0)
Cutaneous epithelial to mesenchymal transition is mediated by TGF-β and TNF-α synergism – implications for scleroderma; winner of Everett C Fox Prize from the American Academy of Dermatology (2011) (0)
Comparison of legal representative and retrospective patient consent in clinical trials in the ICU (2009) (0)
Participant information sheet: recovered capacity (2015) (0)
UK survey of mechanical ventilation and weaning roles responsibilities in pediatric ICUs (2011) (0)
KL-6 in acute lung injury: will it leave its mark? (2008) (0)
Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study (2020) (0)
Epithelial to mesenchymal transition is a novel mechanism of fibrosis in cutaneous disease - implications for scleroderma; winner of the Burrow’s Cup for best oral presentation, Irish Association of Dermatologists Annual Meeting 2011 (2011) (0)
A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm (2015) (0)
Protocol for a systematic review and network meta-analysis of the management of new onset atrial fibrillation in critically unwell adult patients a network meta-analysis of the management of in critically (2019) (0)
16S pan-bacterial PCR can accurately identify patients with ventilator-acquired pneumonia (2015) (0)
A role for the WFDC protein, WAP2, in regulation of innate host defence in the lung (2014) (0)
Effectiveness of a biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use: protocol for a randomised controlled trial (VAPrapid-2) a to reduce for a trial (VAPrapid-2): for a (2016) (0)
Intravenous Allogeneic Human Mesenchymal Stem Cells Restore Alveolar Fluid Clearance In Lungs Rejected For Transplantation In An Ex Vivo Human Lung Perfusion Model (2012) (0)
Effectiveness of a Programme of Exercise on Physical Function in Survivors of Critical Illness Following Discharge from the Intensive Care Unit: a Randomised Controlled Trial. (Poster presentation at the American Thoracic Society, Denver, USA) (2014) (0)
Simvastatin for the prevention and treatment of delirium in critically ill, mechanically ventilated patients (MoDUS): a cost-effectiveness analysis. (2018) (0)
Foxp3+ Macrophages; do they exist? (2012) (0)
Thorax protocol review: working with trialists to improve trial quality (2016) (0)
Effect of total cholesterol and statin therapy on mortality in ARDS patients: a secondary analysis of the SAILS and HARP-2 trials (2023) (0)
S48 NGAL inhibits cytoskeletal re-organisation, MMP-2 production and invasion in alveolar epithelial cells in an in vitro model of acute lung injury (2010) (0)
Quality assessment of diagnostic accuracy studies methodology table (2015) (0)
Parenteral Thiamine (PT) for Prevention and Treatment of Delirium in Critical Illness: A Systematic Review (SR) (0)
Sialic acid-functionalized nanoparticles as a novel anti-inflammatory drug delivery platform (2013) (0)
Effectiveness of a biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use: protocol for a randomised controlled trial (VAPrapid-2) to (2016) (0)
Reply to Zhang and Hei: Mesenchymal Stem Cell–derived Exosomes: Are They Another Therapeutic Method for Extracorporeal Membrane Oxygenation–supported Acute Respiratory Distress Syndrome? (2020) (0)
Do Nonventilatory Strategies for Acute Lung Injury and ARDS Work? (2010) (0)
Reply to Letter: "Effect of Simvastatin on Physiological and Biological Outcomes in Patients Undergoing Esophagectomy: A Randomized Placebo-controlled Trial". (2015) (0)
Treatment With Human Mesenchymal Stem Cells Reduces The Severity Of Acute Lung Injury Over 24 Hours In Sheep Following Inhalation Of Smoke And Instillation Of Pseudomonas Aeruginosa (2012) (0)
Tranilast inhibits cutaneous epithelial to mesenchymal transition – implications for the pathogenesis and treatment of scleroderma ; winner of best registrar's paper at the British Association of Dermatology annual meeting (2011) (0)
Could treatment with immunomodulatory agents targeting IL-1, IL-6, or JAK signalling improve outcomes in patients with severe influenza pneumonia? A systematic and narrative review (2022) (0)
Mechanical ventilation roles and responsibilities in Europe (2011) (0)
Circulating 1,25(OH)2-vitamin D concentration is associated with increased mortality and predicts responsiveness to statins in patients with the acute respiratory distress syndrome. (2017) (0)
Randomized Controlled Trial Of Mononuclear Cell Depletion For Experimental Acute Lung Inflammation (2012) (0)
Proteolytic cleavage of ela fi n by 20 S proteasome may contribute to in fl ammation in acute lung injury (2013) (0)
Re-analysis of ventilator-free days (VFD) in acute respiratory distress syndrome (ARDS) studies (2023) (0)
SeptiFast assay: lysis of whole blood and deoxyribonucleic acid extraction (2015) (0)
The relationship between plasma cystatin C, mortality and acute respiratory distress syndrome subphenotype in the HARP-2 trial (2022) (0)
Completing the laboratory case record form (2015) (0)
Innate Lymphoid Cells Are The Predominant Producers of IL-17A In Acute Lung Injury (2013) (0)
British Thoracic Society winter meeting 2013.: Human Mesenchymal Stem Cells modulate alveolar macrophage polarization in vivo and in vitro. (2013) (0)
Decreased Levels In Elafin Due To Proteolytic Cleavage May Contribute To Alveolar Inflammation In The Pulmonary Compartment In Patients With Acute Lung Injury (2011) (0)
Infection control: helping hands. (Editorial) Practical Patient Care, (2008) (0)
Infiltration Of Rorγt+ Lineage Negative Lymphocytes Into The Lung During Lipopolysaacharide-Induced Acute Lung Injury (2012) (0)
S48 Targeting siglecs to reduce protease-mediated destruction in tuberculosis (2016) (0)
Background and rationale (2015) (0)
Matrix Metalloproteinases And Their Tissue Inhibitors In In-Vitro Models Of Acute Lung Injury (2010) (0)
Clinical data collected for SeptiFast diagnostic validity study (2015) (0)
Temporal Effect On perfused Baseline Nasal Potential Difference Measurement (2010) (0)
The Influence of Orthopedic Surgery on Circulating Metabolite Levels, and their Associations with the Incidence of Postoperative Delirium (2022) (0)
Oral health care in adult intensive care units: A national point prevalence study. (2023) (0)
IL-17A Production Is Important In Neutrophil Migration In A Model Of Lipopolysaccharide-Induced Lung Injury (2012) (0)
University of Birmingham Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by 2-agonists, corticosteroids, and critical illness (2016) (0)
Quantitative oral health assessments in mechanically ventilated patients: A scoping review. (2022) (0)
Reply to: MSC-derived Exosomes: Are They Another Therapeutic Method for ECMO-supported ARDS? (2020) (0)
Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis) (2022) (0)
Participant information sheet: capacity at study commencement (2015) (0)
Acute Respiratory Distress Syndrome (2021) (0)
SURROGATE OUTCOME MEASURES USED IN CRITICAL CARE TRIALS (2016) (0)
Extracorporeal carbon dioxide removal in acute hypoxaemic respiratory failure: a systematic review, Bayesian meta-analysis and trial sequential analysis (2022) (0)
Irish cardiac society (1998) (0)
Valaciclovir for Epstein-Barr virus suppression in moderate-to-severe COPD (EViSCO): A randomised, double-blind, placebo-controlled trial. (2023) (0)
Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial (2023) (0)
Participant consent form: capacity at study commencement (2015) (0)
A national survey of the UK management of coagulapthy in critical care (2010) (0)
Challenging the assumption that laboratory-confirmed diagnosis of bloodstream infection is an error-free gold standard: statistical modelling using latent class analysis (2015) (0)
A185 Infrared thermal imaging of the hand during vascular occlusion in healthy volunteers (2016) (0)
Latent class/finite mixture model specification in Mplus (2015) (0)
Clinical Predictors of Mortality after Six Days of Low Tidal Volume Ventilation for Acute Lung Injury. (2009) (0)
Reply: Importance of the kidney, vessels, and heart with administration of β2 adrenergic receptor agonists in patients susceptible to acute respiratory distress syndrome. (2014) (0)
Repair of Acute Respiratory Distress Syndrome in COVID-19 by Stromal Cell Administration (REALIST-COVID) Phase 2 Randomised Controlled Trial (2022) (0)
Toxic epidermal necrolysis and Stevens-Johnson syndrome : Things we should know ! (2013) (0)
UTILITY OF NEUROPSYCHOLOGICAL TESTS IN PREDICTING POST-OPERATIVE DELIRIUM FOLLOWING ELECTIVE PRIMARY ARTHROPLASTY (2016) (0)
Effectiveness of a biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use: protocol for a randomised controlled trial (VAPrapid-2) a biomarker-based exclusion of ventilator-acquired to reduce antibiotic use: a Study (2016) (0)
Gastrointestinal complications in the intensive care unit (2016) (0)
Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT. (2022) (0)
Alveolar Epithelial And Lung Endothelial Activation/Injury After Inhaled Lipopolysaccharide In Healthy Human Volunteers (2010) (0)
Reply: The alveolar macrophage and acute respiratory distress syndrome: a silent actor? (2014) (0)
Indexing Extravascular Lung Water to Predicted Body Weight Is an Independent Predictor of ICU Mortality in Acute Lung Injury. (2009) (0)
Title : In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury (2006) (0)
Keratinocyte growth factor in acute lung injury--a work in progress. (2009) (0)
Reply to Aberegg and Wolfe: Aspergillosis in the ICU: Hidden Enemy or Bogeyman? (2021) (0)
E-cigarette vapour from base components propylene glycol and vegetable glycerine inhibits the inflammatory response in macrophages and epithelial cells (2022) (0)
Galectin-3 Inhibition in COVID-19 (2022) (0)
Increased Circulating Alpha-1 Antitrypsin Is Associated with a Survival Benefit in Acute Respiratory Distress Syndrome (2020) (0)
Factors influencing resilience to postoperative delirium in adults undergoing elective orthopaedic surgery. (2022) (0)
-ATPase function by hypoxia in rats + -K + Naof transalveolar fluid transport and lung (2015) (0)
Patient demographics of episodes excluded from laboratory analyses (2015) (0)
Receptor For Advanced Glycation End Products (RAGE) Ligands Induce Pulmonary Endothelial And Epithelial Cell NF-?B Activation (2011) (0)
Potential Discordance Between Bayesian and Frequentist Analyses of Randomized Trials in Critical Care Medicine (2020) (0)
Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis (the EASI-SWITCH trial): study protocol for a randomised controlled trial (2020) (0)
Serious adverse event listing (2018) (0)
Intracerebral hemorrhage in ICU: is it worth treating? (2016) (0)
Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery (2019) (0)
Acute hypoxaemic respiratory failure after treatment with lower tidal volume ventilation facilitated by extracorporeal carbon dioxide removal: long-term outcomes from the REST randomised trial (2022) (0)
Heterogeneity of surrogate outcome measures used in critical care studies: A systematic review. (2023) (0)
Trainee Division Survey of Working Patterns, Training and Education (2003) (0)
Statement of patient and public involvement (2015) (0)
Effect of ProtocolizedWeaningWith Early Extubation to Noninvasive Ventilation vs InvasiveWeaning on Time to Liberation FromMechanical Ventilation Among PatientsWith Respiratory Failure The Breathe Randomized Clinical Trial (2018) (0)
Diabetes mellitus is protective against the development of ARDS: an analysis of the LUNG SAFE database (2017) (0)
The COVenT study: developing a core outcome set for mechanical ventilation trials (2015) (0)
European Respiratory Society Internatinal Congress 2014.European Respiratory Journal Sep 2014, 44 (Suppl 58) 3427: Human Mesenchymal Stem Cells modulate alveolar macrophage polarization in vivo and in vitro. (2014) (0)
Swallowing therapy compared to standard care may not have had a beneficial effect on the incidence of pneumonia for patients in acute care. Author’s reply (2021) (0)
The Role of Lymphocytes in Acute Lung Injury (2012) (0)
Proteinase-Activated Receptor 1 (PAR1) Contributes To Acute Lung Injury And Neutrophil Recruitment Via A CCL7-Dependent Mechanism (2012) (0)
Novel anti-tumor necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury (2018) (0)
in Acute Respiratory Distress Syndrome Th17 Cells β α Unexpected Role for Adaptive (2017) (0)
A molecular analysis approach for biofilm quantification (2013) (0)
Plasma Markers of Neurodegeneration Associated with Postoperative Delirium in an Older Elective Arthroplasty Population (2022) (0)
Antioxidants for the Treatment of Endothelial Dysfunction in Critical Illness (2007) (0)
Preoperative Cerebrospinal Fluid and Plasma Markers of Inflammation and Neurodegeneration Predict Mortality Eight Years Later in an Observational Cohort Study of Postoperative delirium in an Older Elective Arthroplasty Populatio (2022) (0)
Cerebrospinal Fluid Markers of Neurodegeneration Associated with Postoperative Delirium in an Older Elective Arthroplasty Population (2022) (0)
Publisher Correction: The effect of blood pressure on mortality following out‑of‑hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database (2023) (0)
Divide and conquer: Identifying Acute Respiratory Distress Syndrome sub-phenotypes (2017) (0)
SeptiFast assay: polymerase chain reaction set-up (2015) (0)
STATIN THERAPY IN CRITICAL ILLNESS (2011) (0)
The role of SOCS2 and SOCS3 in macrophage plasticity and inflammation (2010) (0)
More research is required to understand factors influencing antibiotic prescribing in complex conditions like suspected ventilator-associated pneumonia (2020) (0)
Mesenchymal Stromal Cells Use Extracellular Vesicle-Mediated Mitochondrial Transfer to Modulate Human Macrophage Phenotype Through Enhancement of Oxidative Phosphorylation in the In Vitro and In Vivo Models of the Acute Respiratory Distress Syndrome (2017) (0)
Risk factors for acute organ failure in ICU patients with single organ (respiratory) dysfunction or failure: an international, prospective, cohort study (2012) (0)
Mesenchymal stromal cells (MSC) anti-microbial effect in acute respiratory distress syndrome (ARDS) is mediated in part by enhanced alveolar macrophage phagocytosis through cell contact-dependent mitochondrial transfer leading to improved macrophage bioenergetics (2016) (0)
Lung fluid balance and pulmonary edema in the acute respiratory distress syndrome: modulation by beta adrenergenic stimulation (2004) (0)
Out with the old or better use of the old? A quest in sedation*. (2013) (0)
American Thoracic Society meeting 2017. American Journal of Respiratory and Critical Care Medicine 2017;195:A7504: Mesenchymal Stromal Cells Use Extracellular Vesicle-Mediated Mitochondrial Transfer to Modulate Human Macrophage Phenotype Through Enhancement of Oxidative Phosphorylation in the In Vit (2017) (0)
CSF Aβ42 CONCENTRATION INDEPENDENTLY PREDICTS POSTOPERATIVE DELIRIUM IN AN ELDERLY ELECTIVE ARTHROPLASTY POPULATION (2017) (0)
Potential involvement of monoamine oxidase activity in delirium onset and SARS-COV2 infection (2020) (0)
Impact of MRSA colonization at admission on length of stay and mortality for patients in the ICU (2008) (0)
Potential involvement of monoamine oxidase activity in SARS-COV2 infection and delirium onset (2020) (0)
Impact of a Fully Controlled Ventilation in the First Days of Ards: an Ancillary Analysis of The Lung Safe Study (2017) (0)
A National Survey Of The Management Of Suspected Ventilator-Associated Pneumonia (2012) (0)
Prospective Investigation of Markers of Elevated Delirium Risk (PRIMED Risk) study protocol: a prospective, observational cohort study investigating blood and cerebrospinal fluid biomarkers for delirium and cognitive dysfunction in older patients (2020) (0)
SeptiFast assay: data analysis and reporting (2015) (0)
Beta 2 antagonism in acute respiratory failure (2010) (0)
Feasibility of Slow Continuous Ultrafiltration for Treatment of Fluid Overload in Critical Illness: In Vitro Investigation of Venous Access Options (0)
Decreased levels of elafin in the lungs of patients with acute lung injury as a result of proteolytic cleavage by the proteasome (2012) (0)
The Alveolar Macrophage and Acute Respiratory Distress Syndrome (2014) (0)
Aspirin inhibits neutrophilic inflammation in experimental ALI (2016) (0)
Vascular Responses to Endothelin-1 in Diabetes (1998) (0)
Consultee declaration form (2015) (0)
Discovery of novel metabolomic biomarkers of postoperative delirium in cerebrospinal fluid. (2018) (0)
Significant plasma metabolite alterations in people over 65 going on to develop postoperative delirium. (2019) (0)
TRPC6 inhibitor (BI 764198) to reduce risk and severity of ARDS due to COVID-19: a phase II randomised controlled trial (2023) (0)
Comparison between mortality and airway colonisation versus noncolonisation with Candida species in critically ill adults (2008) (0)
Respiratory Support in the Time of COVID-19. (2022) (0)
Consultee information sheet (2015) (0)
Prevention Of Pulmonary Inflammation And Cellular Injury By Simvastatin In A One Lung Ventilation Model Of ALI In Patients Undergoing Oesophagectomy (2012) (0)
Pleural cavity exploitation in β-Agonist–treated ARDS patients [reply from authors] (2006) (0)
CEREBROSPINAL FLUID/PLASMA ALBUMIN RATIO PREDICTS POSTOPERATIVE DELIRIUM IN AN OLDER ELECTIVE ORTHOPAEDIC POPULATION (2018) (0)
transport in lung and airways Review: Role of aquaporin water channels in fluid Invited Lung Edema Clearance: 20 Years of Progress (2015) (0)
European Respiratory Society International Congress 2017. European Respiratory Journal 2017 50: PA341; DOI: 10.1183/1393003.congress-2017.PA341: Effects of hypercapnic acidosis on the primary cells relevant to ARDS pathophysiology and the therapeutic potential of mesenchymal stem cells (2017) (0)
A randomised trial of the effects on recruitment and retention of including a wet-ink signature and photograph in the patient invitation letter for a clinical trial: results from a Study Within a Trial (SWAT 3 and SWAT 53) (2022) (0)
Effects of hypercapnic acidosis on the primary cells relevant to ARDS pathophysiology and the therapeutic potential of mesenchymal stem cells (2017) (0)
ASpirin as a Treatment for Acute Respiratory Distress Syndrome – a multi-centre, randomised, double-blind, placebo-controlled trial (STAR): study protocol (2018) (0)

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