Daniel I.C. Wang
#31,469
Most Influential Person Now
American academic
Daniel I.C. Wang's AcademicInfluence.com Rankings
Daniel I.C. Wangchemistry Degrees
Chemistry
#815
World Rank
#1347
Historical Rank
#348
USA Rank
Chemical Engineering
#35
World Rank
#43
Historical Rank
#20
USA Rank

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Chemistry
Daniel I.C. Wang's Degrees
- PhD Chemical Engineering University of Pennsylvania
- Masters Chemical Engineering University of Pennsylvania
- Bachelors Chemical Engineering National Taiwan University
Why Is Daniel I.C. Wang Influential?
(Suggest an Edit or Addition)According to Wikipedia, Daniel I-Chyau Wang was a Chinese-American chemical engineer. He was an Institute Professor at the Massachusetts Institute of Technology. He was known for founding the MIT Biotechnology Process Engineering Center and the expansion of the field of biochemical engineering.
Daniel I.C. Wang's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Engineering cell shape and function. (1994) (1340)
- The synthesis of SERS-active gold nanoflower tags for in vivo applications. (2008) (547)
- Silver nanoplates: from biological to biomimetic synthesis. (2007) (483)
- Seedless, Surfactantless, High-Yield Synthesis of Branched Gold Nanocrystals in HEPES Buffer Solution (2007) (338)
- Specific aggregation of partially folded polypeptide chains: The molecular basis of inclusion body composition (1996) (319)
- Identification of active biomolecules in the high-yield synthesis of single-crystalline gold nanoplates in algal solutions. (2007) (299)
- Effects of substratum morphology on cell physiology (1994) (291)
- Uncovering the design rules for peptide synthesis of metal nanoparticles. (2010) (259)
- Measurement of heat evolution and correlation with oxygen consumption during microbial growth (1969) (237)
- Role of arginine in the stabilization of proteins against aggregation. (2005) (228)
- Controlled clustering and enhanced stability of polymer-coated magnetic nanoparticles. (2005) (219)
- Computer‐aided baker's yeast fermentations (1977) (184)
- Polyethylene Glycol Enhanced Protein Refolding (1992) (171)
- Synthesis of Single-Crystalline Gold Nanoplates in Aqueous Solutions through Biomineralization by Serum Albumin Protein (2007) (168)
- Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production. (2001) (161)
- Recyclable nanobiocatalyst for enantioselective sulfoxidation: facile fabrication and high performance of chloroperoxidase-coated magnetic nanoparticles with iron oxide core and polymer shell. (2009) (157)
- Extractive fermentation for lactic acid production (1991) (151)
- Improvement of interferon-gamma sialylation in Chinese hamster ovary cell culture by feeding of N-acetylmannosamine. (1998) (149)
- Apoptosis in batch cultures of Chinese hamster ovary cells. (1999) (149)
- Polyethylene glycol enhanced refolding of bovine carbonic anhydrase B. Reaction stoichiometry and refolding model. (1992) (149)
- Viscous reduction of turbulent damage in animal cell culture (1989) (140)
- Computer‐aided material balancing for prediction of fermentation parameters (1977) (136)
- A liquid emulsion membrane process for the separation of amino acids (1990) (133)
- Effect of Microwaves on Escherichia coli and Bacillus subtilis. (1967) (133)
- Metabolism of peptide amino acids by Chinese hamster ovary cells grown in a complex medium. (1999) (133)
- Metabolic flux analysis of hybridoma continuous culture steady state multiplicity. (1999) (132)
- Refolding and aggregation of bovine carbonic anhydrase B: quasi-elastic light scattering analysis. (1990) (131)
- Metabolic effects on recombinant interferon‐γ glycosylation in continuous culture of Chinese hamster ovary cells (1999) (128)
- Separation of proteins and viruses using two-phase aqueous micellar systems. (1998) (126)
- High cell density and high monoclonal antibody production through medium design and rational control in a bioreactor. (2000) (124)
- Separation and concentration of amino acids using liquid emulsion membranes (1988) (119)
- Elucidation of Growth Inhibition and Acetic Acid Production by Clostridium thermoaceticum (1984) (118)
- Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis (2016) (118)
- Cosolvent Assisted Protein Refolding (1990) (113)
- Microcarrier cell culture: New methods for research-scale application (1977) (108)
- A mechanistic analysis of the inoculum requirement for the cultivation of mammalian cells on microcarriers (1985) (97)
- Strategies for reducing solvent toxicity in extractive fermentations (1991) (94)
- Effect of shear on the death of two strains of mammalian tissue cells (1971) (92)
- Single-cell protein II (1975) (90)
- Polymerization mechanism of polypeptide chain aggregation. (1997) (89)
- Enhancing recombinant glycoprotein sialylation through CMP‐sialic acid transporter over expression in Chinese hamster ovary cells (2006) (88)
- Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal cells in bioreactor (2004) (88)
- RNA interference of sialidase improves glycoprotein sialic acid content consistency (2006) (87)
- Ethanol from cellulosic biomass (1983) (80)
- PRODUCTION OF CELL‐DERIVED PRODUCTS: VIRUS AND INTERFERON * (1981) (80)
- Selective solvent delignification for fermentation enhancement (1983) (77)
- Application of ultrafiltration for enzyme. Retention during continuous enzymatic reaction (1970) (76)
- Analysis of mass transfer for immobilized cells in an extractive lactic acid fermentation (1991) (75)
- COALESCENCE AND SOLUBILIZATE EXCHANGE IN A CATIONIC FOUR-COMPONENT REVERSED MICELLAR SYSTEM (1990) (67)
- Affinity–based reversed micellar protein extraction: I. Principles and protein–ligand systems (1993) (66)
- Enhancing gas‐liquid mass transfer rates in non‐newtonian fermentations by confining mycelial growth to microbeads in a bubble column (1983) (65)
- Gamma-interferon production and quality in stoichiometric fed-batch cultures of Chinese hamster ovary (CHO) cells under serum-free conditions. (1997) (64)
- Energy metabolism and ATP balance in animal cell cultivation using a stoichiometrically based reaction network (2000) (63)
- Water transport mechanism in liquid emulsion membrane process for the separation of amino acids (1990) (63)
- Fundamental Investigation of Protein Partitioning in Two-Phase Aqueous Mixed (Nonionic/Ionic) Micellar Systems (2002) (63)
- Kinetics of Death of Bacterial Spores at Elevated Temperatures (1964) (62)
- Aspartic Acid Synthesis of Crystalline Gold Nanoplates, Nanoribbons, and Nanowires in Aqueous Solutions (2008) (60)
- Cell death from bursting bubbles: role of cell attachment to rising bubbles in sparged reactors. (1999) (58)
- A comprehensive picture of non-site specific oxidation of methionine residues by peroxides in protein pharmaceuticals. (2004) (57)
- Effects of paddle impeller geometry on power input and mass transfer in small‐scale animal cell culture vessels (1989) (57)
- Bio-Based Industrial Products: Priorities for Research and Commercialization (2000) (56)
- Virus production with a newly developed microcarrier system (1977) (55)
- Enhanced Oxygen Transfer Using Oil‐in‐Water Dispersions a (1987) (54)
- Human interferon production with diploid fibroblast cells grown on microcarriers (1979) (54)
- Application of destabilizing sequences on selection marker for improved recombinant protein productivity in CHO-DG44. (2007) (52)
- Glucose-6-phosphate dehydrogenase partitioning in two-phase aqueous mixed (nonionic/cationic) micellar systems. (2003) (51)
- Facile fabrication of recyclable and active nanobiocatalyst: purification and immobilization of enzyme in one pot with Ni-NTA functionalized magnetic nanoparticle. (2011) (49)
- Metabolic effects on recombinant interferon-gamma glycosylation in continuous culture of Chinese hamster ovary cells (2000) (48)
- Fluorescence sensing of fermentation parameters using fiber optics (1988) (48)
- Bioreduction with Efficient Recycling of NADPH by Coupled Permeabilized Microorganisms (2008) (47)
- Growth of Enterobacter aerogenes in a chemostat with double nutrient limitations (1976) (46)
- Molecular dynamics simulations and oxidation rates of methionine residues of granulocyte colony-stimulating factor at different pH values. (2004) (46)
- Rapid monitoring of site-specific glycosylation microheterogeneity of recombinant human interferon-gamma. (1996) (45)
- Separating lysozyme from bacteriophage P22 in two-phase aqueous micellar systems. (2002) (44)
- Cell death from bursting bubbles: Role of cell attachment to rising bubbles in sparged reactors (1999) (43)
- Bioreactor System with Solvent Extraction for Organic Acid Production a (1987) (43)
- Mechanistic study on the bis(p-sulfonatophenyl)phenylphosphine synthesis of monometallic Pt hollow nanoboxes using Ag*-Pt core-shell nanocubes as sacrificial templates (2007) (43)
- Quantitative analysis and process monitoring of site-specific glycosylation microheterogeneity in recombinant human interferon-γ from Chinese hamster ovary cell culture by hydrophilic interaction chromatography (1998) (43)
- Site- and branch-specific sialylation of recombinant human interferon-gamma in Chinese hamster ovary cell culture. (1997) (42)
- Mitochondrial membrane potential differentiates cells resistant to apoptosis in hybridoma cultures. (2000) (42)
- Use of surface aerator improve oxygen transfer in cell culture. (1986) (42)
- Effects of Antioxidants on the Hydrogen Peroxide-Mediated Oxidation of Methionine Residues in Granulocyte Colony-Stimulating Factor and Human Parathyroid Hormone Fragment 13-34 (2004) (42)
- Optimization in the recovery of a labile intracellular enzyme (1974) (41)
- Understanding viral partitioning in two-phase aqueous nonionic micellar systems: 2. Effect of entrained micelle-poor domains. (2002) (41)
- Affinity-enhanced protein partitioning in decyl beta-D-glucopyranoside two-phase aqueous micellar systems. (2005) (40)
- Production of human immune interferon by recombinant mammalian cells cultivated on microcarriers (1989) (40)
- Comparative oxidation studies of methionine residues reflect a structural effect on chemical kinetics in rhG-CSF. (2006) (40)
- Induced flocculation of animal cells in suspension culture (1989) (39)
- Effects of Excipients on the Hydrogen Peroxide-Induced Oxidation of Methionine Residues in Granulocyte Colony-Stimulating Factor (2004) (38)
- Influence of Primatone RL supplementation on sialylation of recombinant human interferon-gamma produced by Chinese hamster ovary cell culture using serum-free media. (1997) (38)
- Characterization of pore size distribution of packing materials used in perfusion chromatography using a network model (1995) (37)
- Animal cell bioreactors. (1991) (36)
- Automated process monitoring of monoclonal antibody production. (1993) (35)
- Protein resources and technology : status and research needs (1975) (34)
- A new sensor, the “filtration probe,” for quantitative characterization of the penicillin fermentation. I. Mycelial morphology and culture activity (1981) (34)
- Fiber bed reactor design for animal cell culture (1989) (33)
- A high-throughput method for quantification of glycoprotein sialylation. (2010) (33)
- Enhancing Enantioselectivity and Productivity of P450-Catalyzed Asymmetric Sulfoxidation with an Aqueous/Ionic Liquid Biphasic System (2014) (32)
- Understanding viral partitioning in two-phase aqueous nonionic micellar systems: 1. Role of attractive interactions between viruses and micelles. (2002) (32)
- The Practice of biotechnology : current commodity products (1985) (30)
- Selection of microcarrier diameter for the cultivation of mammalian cells on microcarriers (1987) (30)
- Direct Microbiological Conversion of Cellulosics to Ethanol (1980) (30)
- General method for extended metal nanowire synthesis : Ethanol induced self-assembly (2007) (29)
- Fermentation and enzyme technology (1979) (28)
- Simultaneous measurement of oxygen diffusion coefficients and solubilities in electrolyte solutions with a polarographic oxygen electrode (1988) (28)
- Hydrodynamic effects on animal cells in microcarrier bioreactors. (1991) (27)
- Liquid emulsion membranes and their applications in biochemical separations (1986) (27)
- Increased oxygen mass transfer rates from single bubbles in microbial systems at low reynolds numbers (1969) (27)
- Estimating cell concentration in the presence of suspended solids: A light scatter technique (1992) (27)
- Production of emulsan in a fermentation process using soybean oil (SBO) in a carbon-nitrogen coordinated feed. (1990) (27)
- Immobilization of l-lactate dehydrogenase on magnetic nanoclusters for chiral synthesis of pharmaceutical compounds (2009) (26)
- Preparation and properties of immobilized methanol oxidase (1978) (26)
- Morphosynthesis of Gold Nanoplates in Polypeptide Multilayer Films (2009) (25)
- Xanthine-Oxidase Reactivity in Reversed Micellar Systems - A Contribution to the Prediction of Enzymatic-Activity in Organized Media (1995) (24)
- Evaluation of different promoters and host strains for the high-level expression of collagen-like polymer in Escherichia coli. (2003) (24)
- Cell adsorption and local accumulation of extracellular polysaccharide in an immobilized Acinetobacter calcoaceticus system (1989) (23)
- Techniques for the Estimation of Cell Concentration in the Presence of Suspended Solids (1992) (22)
- A structural and mechanistic study of the oxidation of methionine residues in hPTH(1-34) via experiments and simulations. (2004) (21)
- A new sensor, the “filtration probe,” for quantitative characterization of the penicillin fermentation. II. The monitor of mycelial growth (1981) (21)
- Production of acetic acid by immobilized whole cells ofClostridium thermoaceticum (1983) (21)
- A GFP-based screen for growth-arrested, recombinant protein-producing cells. (2002) (20)
- Chaetomium cellulolyticum, growth behavior on cellulose and protein production (1978) (19)
- Template-free synthesis of porous platinum networks of different morphologies. (2009) (19)
- Effect of centrifugation on the viability of Burkitt lymphoma cells (1968) (19)
- Concurrent oxidations with tandem biocatalysts in one pot: green, selective and clean oxidations of methylene groups to ketones. (2011) (19)
- Augmentation of mass transfer through electrical means for hydrogel‐entrapped Escherichia coli cultivation (1995) (18)
- Cosolvent Effects on Refolding and Aggregation (1993) (17)
- Enzyme and bacteriophage concentration by membrane filtration. (1968) (17)
- Enzyme Processing Using Ultrafiltration Membranes (1970) (17)
- Equilibrium Association of a Molten Globule Intermediate in the Refolding of Bovine Carbonic Anhydrase (1991) (17)
- A new sensor—the “filtration Probe”— for quantitative characterization of penicillin fermentation. III. An automatically operating probe (1983) (16)
- Fibroblast growth factor 2 enhances early stages of in vitro endothelial repair by microfilament bundle reorganization and cell elongation. (1999) (16)
- Algae, bacteria, and yeasts as food or feed (1970) (16)
- Pore dimension effects in the cell loading of a porous carrier. (1989) (15)
- Cultivation of virus antigen in fibroblast cells using a glass fiber bed reactor (1993) (15)
- Sugar accumulation during enzyme hydrolysis and fermentation of cellulose (1978) (15)
- Experimental Collision Efficiencies of Polymer‐Flocculated Animal Cells (1990) (14)
- Penicillin fermentation in a 200-Liter tower fermentor using cells confined to microbeads (1984) (14)
- Reversible removal and hydrodynamic phenomena in CHO microcarrier cultures. (1990) (12)
- Molecular thermodynamic model for Helix‐Helix docking and protein aggregation (1995) (12)
- Collection of microbial cells. (1970) (12)
- Biotechnology : status and perspectives (1988) (10)
- A simple and rapid assay of collagen-like polymer in crude lysate from Escherichia coli. (2002) (10)
- Simple method for determining cell and hydrocarbon concentration during fermentation (1972) (10)
- Quantitative analysis and process monitoring of site-specific glycosylation microheterogeneity in recombinant human interferon-gamma from Chinese hamster ovary cell culture by hydrophilic interaction chromatography. (1998) (10)
- On-line gas analysis for material balances and control (1979) (10)
- Effective diffusivity of oxygen in microbial pellets. (1984) (10)
- [28] Immobilization of mycelial cells on celite (1987) (9)
- Effect of Substratum Morphology on Animal Cell Adhesion and Behavior (1991) (9)
- Chapter 12 – Exploitation of Multienzyme Systems for Synthesis (1977) (9)
- Degradation of cellulosic biomass and its subsequent utilization for the production of chemical feedstocks: Subcontract progress report, 1 September 1980-28 February 1981 (1977) (9)
- OPTIMIZING PARAMETERS FOR GROWTH OF ANCHORAGE-DEPENDENT MAMMALIAN CELLS IN MICROCARRIER CULTURE (1977) (8)
- New microcarriers for the large scale production of anchorage-dependent mammalian cells. (1978) (8)
- Process monitoring of the production of γ-interferon in recombinant chinese hamster ovary cells (1994) (8)
- Cell Protein II (1977) (7)
- Enzyme Reactions for Preparative Scale Synthesis (1974) (7)
- Parameters affecting cell growth on reduced charge microcarriers. (1979) (6)
- Computer‐aided material balancing for prediction of fermentation parameters (1977) (6)
- Kinetics of the enzymatic synthesis of peptide antibiotics. (1977) (6)
- In vitro Protein Refolding (1992) (6)
- BIOTECHNOLOGY: PAST, PRESENT AND FUTURE (1984) (6)
- PRELIMINARY STUDIES ON EXTRACTIVE PHENYLALANINE FERMENTATION WITH UNCHARGED POLYMERIC BEADS (2004) (5)
- Low cost and convenient method for off-gas flowrate determination in industrial fermenters (1990) (5)
- The application of dynamic calorimetry for monitoring growth ofSaccharomyces cerevisiae (2004) (5)
- EXTRACTIVE FERMENTATION OF PHENYLALANINE USING UNCHARGED POLYMERIC BEADS (2005) (4)
- Industrial Animal Cell Culture (2001) (4)
- THE ENHANCEMENT OF PRODUCTION OF PHENYLALANINE BY EXTRACTIVE FERMENTATION WITH POLYMERIC BEADS (2004) (4)
- Understanding Oxidative Instability of Protein Pharmaceuticals (2004) (4)
- High‐throughput analysis of intraclonal variability of glycoprotein sialylation (2012) (3)
- ENZYMATIC OXIDATION OF METHANOL TO PRODUCE FORMALDEHYDE AND HYDROGEN PEROXIDE (1981) (3)
- Developments in agitation and aeration of fermentation systems. (1968) (3)
- Degradation of cellulosic biomass and its subsequent utilization for the production of chemical feedstocks. Progress report, December 1, 1976--February 28, 1977 (1977) (3)
- Degradation of cellulosic biomass and its subsequent utilization for the production of chemical feedstocks. Progress report, March 1-August 31, 1980 (1980) (3)
- Monitoring and Characterization of Glycoprotein Quality in Animal Cell Cultures (1998) (3)
- ENZYMATIC SYNTHESIS OF THE ANTIBIOTIC GRAMICIDIN S: KINETICS OF INHIBITION AND ENZYME DESTABILIZATION (1981) (3)
- Utilization of mesquite and honey locust pods as feedstocks for energy production. (1980) (3)
- Computer control of the penicillin fermentation using the filtration probe in conjunction with a structured process model (2006) (3)
- Degradation of cellulosic biomass and its subsequent utilization for the production of chemical feedstocks. Progress report, September 1-November 30, 1978 (1978) (2)
- Scale-up of Oxygen Transfer in Animal Cell Cultures (1989) (2)
- Introduction to the symposium on engineering aspects of fermentation, third international fermentation symposium (1969) (2)
- Immobilized animal cell bioreactors. (1995) (2)
- A NEW SENSOR, THE “FILTRATION PROBE”, TO MONITOR AND CONTROL ANTIBIOTIC FERMENTATIONS (1981) (2)
- Sensors for Bioprocess Monitoring and Control (1993) (2)
- Molecular computations for reactions and phase transitions: applications to protein stabilization, hydrates and catalysis (2005) (1)
- Degradation of lignocellulosic biomass and its subsequent utilization for the production of liquid fuels: Subcontract progress report, 1 March 1982-31 August 1982 (1987) (1)
- Biological Routes to Gold Nanoplates (2005) (1)
- Enhancing Production of Recombinant Proteins from Mammalian Cells (2003) (1)
- Retargeting of pre-set regions on chromosome for high gene expression in mammalian cells (2005) (1)
- Degradation of cellulosic biomass and its subsequent utilization for the production of chemical feedstocks. Progress report, June 1, 1977--August 31, 1977 (1977) (1)
- The Effect of Culture Temperature on Recombinant IFN-γ Production and Quality (2004) (1)
- The principles, applications and regulations of biotechnology in industry, agriculture and medicine, Vol. 1.. Pergamon Press, Oxford, New York, Toronto, Sydney (1985), Prix: US $ 995.00 / £ 695.00 (1986) (1)
- Stabilization of Therapeutic Proteins (2003) (1)
- Process monitoring of the production of gamma-interferon in recombinant Chinese hamster ovary cells. (1994) (1)
- A Population Balance Model for the Determination of Solubilizate Exchange Rate Constants in Reversed Micellar Systems (1990) (1)
- Engineering Mammalian Cells for Improved Recombinant Protein Production (2003) (0)
- GrowthofEnterobacter aerogenesina Chemostat with DoubleNutrient Limitations (1976) (0)
- Biotechnology of mammalian cells (2008) (0)
- CHAETOMIUM CELLULOLYTICUM, GROWTH (2016) (0)
- Connecting, Cultivating, Catalyzing: Update on SBE activities (2005) (0)
- Implications of Vector Fragmentation and Initial Production Levels in Production Cell Line Development Using MTX (2012) (0)
- Stabilization of Proteins against Aggregation (2004) (0)
- On the Oxidation of Methionine Residues during the Storage of Protein Pharmaceuticals in an Aqueous Formulation (2004) (0)
- Simple and Versatile Route to the Synthesis of Anisotropic Bimetallic Core-Shell and Monometallic Hollow Nanostructures: Ag (AgCl)-Pt Core-Shell Nanocubes and Pt Nanoboxes (2007) (0)
- Reduced Temperature Production of Recombinant Proteins to Increase Productivity in Mammalian Cell Culture (2004) (0)
- CIRP Expression on Growth and Productivity of CHO Cells (2006) (0)
- Cell-line Engineering of Chinese Hamster Ovary Cells for Low-temperature Culture (2005) (0)
- Kinetics of 125 I-BSA Binding to Monoclonal Anti-BSA Immobilized on 0.5㎛ Polystyrene Beads (1996) (0)
- Variability in the Stability and Productivity of Transfected Genes in Chinese Hamster Ovary (CHO) cells (2005) (0)
- Reactions in Micelles, Monolayers, and Liquid Crystals (1991) (0)
- 407 Biotechnology : Present Status and Future Perspectives (1984) (0)
- Effect of Gas Sparging in Mammalian Cell Bioreactors (2005) (0)
- Measurement of heat evolution and correlation with oxygen consumption during microbial growth (2000) (0)
- SOURCES OF PROTEIN FOR MAN: THE RESEARCH NEEDS (1977) (0)
- Integration of Bioprocesses (2008) (0)
- Development and characterization of ethanol tolerance in Closteridium thermocellum. (1979) (0)
- A light scatter biosensor for cell concentration estimation in the presence of solid substrate (1990) (0)
- Degradation of lignocellulosic biomass and its subsequent utilization for the production of liquid fuels: Subcontract progress report, 1 March 1984-28 February 1985 (1987) (0)
- In vitroProtein Refolding (2001) (0)
- Degradation of cellulosic biomass and its subsequent utilization for the production of chemical feedstocks: Subcontract progress report, 1 March 1979-31 August 1979 (1987) (0)
- Cell-line Engineering for Low-temperature Growth (2004) (0)
- Degradation of lignocellulosic biomass and its subsequent utilization for the production of liquid fuels: Subcontract progress report, 1 September 1981-28 February 1982 (1987) (0)
- Over Expression of the CMP-sialic Acid Transporter in Chinese Hamster Ovary Cells Leads to Increased Sialylation (2005) (0)
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