Daniel J. Klionsky
#34,208
Most Influential Person Now
American biochemist and molecular biologist
Daniel J. Klionsky's AcademicInfluence.com Rankings
Daniel J. Klionskybiology Degrees
Biology
#1021
World Rank
#1764
Historical Rank
#540
USA Rank
Molecular Biology
#91
World Rank
#94
Historical Rank
#57
USA Rank
Biochemistry
#116
World Rank
#151
Historical Rank
#65
USA Rank
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Biology
Daniel J. Klionsky's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Daniel J. Klionsky Influential?
(Suggest an Edit or Addition)According to Wikipedia, Daniel Jay Klionsky is an American biochemist and molecular biologist. He is the Alexander G. Ruthven Professor of Life Sciences and professor of molecular, cellular, and developmental biology at the University of Michigan. As a cell biologist, Klionsky pioneered the understanding of autophagy, the process by which cells break down to survive stress conditions such as starvation, and the role autophagy plays in cancer, neurodegenerative diseases, and other areas of human health.
Daniel J. Klionsky's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
- Autophagy fights disease through cellular self-digestion (2008) (5918)
- Development by self-digestion: molecular mechanisms and biological functions of autophagy. (2004) (3734)
- Autophagy as a regulated pathway of cellular degradation. (2000) (3473)
- Regulation mechanisms and signaling pathways of autophagy. (2009) (3280)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Autophagy in Health and Disease: A Double-Edged Sword (2004) (2503)
- Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
- Autophagosome formation: core machinery and adaptations (2007) (2099)
- Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes (2009) (2078)
- Eaten alive: a history of macroautophagy (2010) (1931)
- Autophagy: from phenomenology to molecular understanding in less than a decade (2007) (1873)
- Mammalian autophagy: core molecular machinery and signaling regulation. (2010) (1809)
- A protein conjugation system essential for autophagy (1998) (1567)
- The machinery of macroautophagy (2013) (1522)
- Autophagy: molecular machinery for self-eating (2005) (1469)
- An overview of autophagy: morphology, mechanism, and regulation. (2014) (1350)
- A unified nomenclature for yeast autophagy-related genes. (2003) (1235)
- Potential therapeutic applications of autophagy (2007) (1006)
- Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases (1988) (982)
- The molecular machinery of autophagy: unanswered questions (2005) (951)
- Endoplasmic Reticulum Stress Triggers Autophagy* (2006) (943)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) (799)
- The Atg8 and Atg12 ubiquitin‐like conjugation systems in macroautophagy (2008) (764)
- Protein turnover via autophagy: implications for metabolism. (2007) (752)
- Atg32 is a mitochondrial protein that confers selectivity during mitophagy. (2009) (734)
- The fungal vacuole: composition, function, and biogenesis. (1990) (719)
- An overview of the molecular mechanism of autophagy. (2009) (694)
- Atg8 controls phagophore expansion during autophagosome formation. (2008) (681)
- Methods for Monitoring Autophagy from Yeast to Human (2007) (668)
- Cargo recognition and degradation by selective autophagy (2018) (653)
- The regulation of autophagy – unanswered questions (2011) (600)
- Autophagy in the Eukaryotic Cell (2002) (550)
- The Molecular Mechanism of Autophagy (2003) (537)
- In search of an “autophagomometer” (2009) (518)
- Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein (2007) (510)
- Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway (1995) (497)
- Vacuolar import of proteins and organelles from the cytoplasm. (1999) (470)
- The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. (2004) (458)
- Does bafilomycin A1 block the fusion of autophagosomes with lysosomes? (2008) (439)
- Autophagy: machinery and regulation (2016) (425)
- SNARE Proteins Are Required for Macroautophagy (2011) (420)
- Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting (1988) (403)
- The return of the nucleus: transcriptional and epigenetic control of autophagy (2013) (397)
- Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. (2000) (382)
- Ferroptosis is a type of autophagy-dependent cell death. (2020) (381)
- Apg9p/Cvt7p Is an Integral Membrane Protein Required for Transport Vesicle Formation in the Cvt and Autophagy Pathways (2000) (375)
- Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway (1992) (374)
- Autophagy revisited: A conversation with Christian de Duve (2008) (367)
- An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis (2010) (367)
- Mitochondria removal by autophagy (2011) (364)
- Ferroptosis: machinery and regulation (2020) (361)
- Autophagic Processes in Yeast: Mechanism, Machinery and Regulation (2013) (358)
- Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway. (2002) (353)
- Autophagy and Human Disease (2007) (350)
- Cargo Proteins Facilitate the Formation of Transport Vesicles in the Cytoplasm to Vacuole Targeting Pathway* (2004) (338)
- Two Distinct Pathways for Targeting Proteins from the Cytoplasm to the Vacuole/Lysosome (1997) (337)
- AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc – Activity (2018) (335)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. (1989) (312)
- Mitophagy in Yeast Occurs through a Selective Mechanism* (2008) (311)
- Convergence of Multiple Autophagy and Cytoplasm to Vacuole Targeting Components to a Perivacuolar Membrane Compartment Prior tode Novo Vesicle Formation* (2002) (293)
- The Cvt pathway as a model for selective autophagy (2010) (291)
- How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy. (2015) (289)
- How to live long and prosper: autophagy, mitochondria, and aging. (2008) (284)
- Dissection of Autophagosome Biogenesis into Distinct Nucleation and Expansion Steps (2000) (283)
- Autophagy in major human diseases (2021) (282)
- Autophagosomes: biogenesis from scratch? (2005) (277)
- The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae. (2007) (277)
- Atg9 Cycles Between Mitochondria and the Pre-Autophagosomal Structure in Yeasts (2005) (273)
- Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway. (2005) (272)
- Atg22 recycles amino acids to link the degradative and recycling functions of autophagy. (2006) (271)
- Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy (2010) (266)
- Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. (1996) (266)
- Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information (1988) (265)
- Genetic and Phenotypic Overlap between Autophagy and the Cytoplasm to Vacuole Protein Targeting Pathway* (1996) (262)
- A comprehensive glossary of autophagy-related molecules and processes (2nd edition) (2011) (259)
- The role of autophagy in Parkinson's disease. (2012) (257)
- Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway. (2001) (256)
- Aup1p, a Yeast Mitochondrial Protein Phosphatase Homolog, Is Required for Efficient Stationary Phase Mitophagy and Cell Survival* (2007) (254)
- A comprehensive glossary of autophagy-related molecules and processes (2010) (253)
- The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy (2013) (253)
- Cvt9/Gsa9 Functions in Sequestering Selective Cytosolic Cargo Destined for the Vacuole (2001) (252)
- Autophagy-Dependent Ferroptosis: Machinery and Regulation. (2020) (249)
- Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae. (2007) (248)
- In vivo evidence for the role of the epsilon subunit as an inhibitor of the proton-translocating ATPase of Escherichia coli (1984) (246)
- Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins (2014) (243)
- A genomic screen for yeast mutants defective in selective mitochondria autophagy. (2009) (243)
- Posttranslational modification of autophagy-related proteins in macroautophagy (2015) (241)
- Membrane Recruitment of Aut7p in the Autophagy and Cytoplasm to Vacuole Targeting Pathways Requires Aut1p, Aut2p, and the Autophagy Conjugation Complex (2001) (240)
- The Itinerary of a Vesicle Component, Aut7p/Cvt5p, Terminates in the Yeast Vacuole via the Autophagy/Cvt Pathways* (2000) (239)
- Potential function for the Huntingtin protein as a scaffold for selective autophagy (2014) (235)
- Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. (2004) (231)
- Apg13p and Vac8p Are Part of a Complex of Phosphoproteins That Are Required for Cytoplasm to Vacuole Targeting* (2000) (225)
- Atg17 regulates the magnitude of the autophagic response. (2005) (225)
- Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein (2020) (221)
- The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy. (2013) (221)
- Molecular Mechanisms of Autophagy in the Cardiovascular System (2015) (217)
- Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways. (1999) (217)
- Endoplasmic Reticulum Stress: A New Pathway to Induce Autophagy (2007) (216)
- Degradation of Lipid Vesicles in the Yeast Vacuole Requires Function of Cvt17, a Putative Lipase* (2001) (211)
- Clockophagy is a novel selective autophagy process favoring ferroptosis (2019) (207)
- The Ras/cAMP-dependent Protein Kinase Signaling Pathway Regulates an Early Step of the Autophagy Process in Saccharomyces cerevisiae* (2004) (206)
- Peroxisome degradation in Saccharomyces cerevisiae is dependent on machinery of macroautophagy and the Cvt pathway. (1999) (206)
- Multiple roles of the cytoskeleton in autophagy (2009) (203)
- Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast (2006) (202)
- Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris. (2001) (202)
- Cooperative Binding of the Cytoplasm to Vacuole Targeting Pathway Proteins, Cvt13 and Cvt20, to Phosphatidylinositol 3-Phosphate at the Pre-autophagosomal Structure Is Required for Selective Autophagy* (2002) (201)
- Autophagy and disease: unanswered questions (2020) (201)
- Dual roles of Atg8−PE deconjugation by Atg4 in autophagy (2012) (200)
- The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy (2010) (200)
- Autophagy in yeast: a review of the molecular machinery. (2002) (198)
- Eating the endoplasmic reticulum: quality control by autophagy. (2007) (193)
- Necrotic, apoptotic and autophagic cell fates triggered by nanoparticles (2018) (191)
- A role for Atg8–PE deconjugation in autophagosome biogenesis (2012) (183)
- The Mechanism and Physiological Function of Macroautophagy (2013) (181)
- Post-Golgi Sec Proteins Are Required for Autophagy in Saccharomyces cerevisiae (2010) (181)
- Autophagy in Yeast: Mechanistic Insights and Physiological Function (2001) (177)
- An overview of macroautophagy in yeast. (2016) (174)
- Atg27 is required for autophagy-dependent cycling of Atg9. (2006) (172)
- Vacuolar Localization of Oligomeric α-Mannosidase Requires the Cytoplasm to Vacuole Targeting and Autophagy Pathway Components in Saccharomyces cerevisiae * (2001) (171)
- Aminopeptidase I Is Targeted to the Vacuole by a Nonclassical Vesicular Mechanism (1997) (168)
- Biochemical methods to monitor autophagy-related processes in yeast. (2008) (168)
- Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae (2011) (167)
- Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism. (2019) (165)
- Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. (2003) (164)
- Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos (2009) (164)
- Approaching the Molecular Mechanism of Autophagy (2001) (164)
- Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes… Wait, I’m confused (2014) (163)
- The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae. (2005) (161)
- Apg2 Is a Novel Protein Required for the Cytoplasm to Vacuole Targeting, Autophagy, and Pexophagy Pathways* (2001) (158)
- Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death (2020) (154)
- Molecular Mechanisms and Regulation of Specific and Nonspecific Autophagy Pathways in Yeast* (2005) (150)
- Transport of a Large Oligomeric Protein by the Cytoplasm to Vacuole Protein Targeting Pathway (1997) (149)
- A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy. (2010) (146)
- Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay (2016) (145)
- Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. (2004) (145)
- How Shall I Eat Thee? (2007) (142)
- PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism. (2018) (140)
- The regulation of aging: does autophagy underlie longevity? (2009) (139)
- The quantitative Pho8Delta60 assay of nonspecific autophagy. (2008) (134)
- Roles of the Lipid-binding Motifs of Atg18 and Atg21 in the Cytoplasm to Vacuole Targeting Pathway and Autophagy* (2010) (133)
- The Ccz1-Mon1 Protein Complex Is Required for the Late Step of Multiple Vacuole Delivery Pathways* (2002) (133)
- The molecular mechanism of mitochondria autophagy in yeast (2010) (133)
- The variability of autophagy and cell death susceptibility (2013) (129)
- AMPK-dependent phosphorylation of ULK1 induces autophagy. (2011) (127)
- Regulation of autophagy: Modulation of the size and number of autophagosomes (2014) (121)
- A Cycling Protein Complex Required for Selective Autophagy (2007) (120)
- Arp2 links autophagic machinery with the actin cytoskeleton. (2008) (119)
- Autophagy and p70S6 Kinase (2005) (119)
- Phosphatidylinositol-3-Phosphate Clearance Plays a Key Role in Autophagosome Completion (2012) (118)
- Autophagy wins the 2016 Nobel Prize in Physiology or Medicine: Breakthroughs in baker's yeast fuel advances in biomedical research (2016) (118)
- Yeast homotypic vacuole fusion requires the Ccz1–Mon1 complex during the tethering/docking stage (2003) (116)
- Self-interaction is critical for Atg9 transport and function at the phagophore assembly site during autophagy. (2008) (113)
- Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: potential commercial applications (1996) (112)
- Regulation of macroautophagy in Saccharomyces cerevisiae. (2010) (108)
- Vps51 Is Part of the Yeast Vps Fifty-three Tethering Complex Essential for Retrograde Traffic from the Early Endosome and Cvt Vesicle Completion* (2003) (106)
- V1-situated Stalk Subunits of the Yeast Vacuolar Proton-translocating ATPase* (1997) (104)
- Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy (2008) (104)
- Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase (2011) (102)
- Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I (1996) (101)
- Autophagy in organelle homeostasis: peroxisome turnover. (2006) (99)
- Cell biology: Regulated self-cannibalism (2004) (99)
- Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress. (2017) (97)
- Coming soon to a journal near you—The updated guidelines for the use and interpretation of assays for monitoring autophagy (2014) (97)
- Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly. (1996) (97)
- Delivery of proteins and organelles to the vacuole from the cytoplasm. (1998) (96)
- Ume6 transcription factor is part of a signaling cascade that regulates autophagy (2012) (91)
- Rph1/KDM4 Mediates Nutrient-Limitation Signaling that Leads to the Transcriptional Induction of Autophagy (2015) (90)
- Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways. (2000) (90)
- Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium (2015) (90)
- Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy (2009) (89)
- Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation (2013) (89)
- Transcriptional Regulation by Pho23 Modulates the Frequency of Autophagosome Formation (2014) (88)
- Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability. (2013) (88)
- BECN1 is a new driver of ferroptosis (2018) (87)
- Atg23 Is Essential for the Cytoplasm to Vacuole Targeting Pathway and Efficient Autophagy but Not Pexophagy* (2003) (86)
- SnapShot: Selective Autophagy (2013) (85)
- Autophagy core machinery: overcoming spatial barriers in neurons (2016) (85)
- Relieving Autophagy and 4EBP1 from Rapamycin Resistance (2011) (84)
- A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy (2015) (83)
- Aspartyl Aminopeptidase Is Imported from the Cytoplasm to the Vacuole by Selective Autophagy in Saccharomyces cerevisiae* (2011) (80)
- Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures (2012) (79)
- Monitoring mitophagy in yeast: The Om45-GFP processing assay (2009) (79)
- Compartment acidification is required for efficient sorting of proteins to the vacuole in Saccharomyces cerevisiae. (1992) (77)
- Ferritinophagy and ferroptosis in the management of metabolic diseases (2021) (77)
- Autophagy and SARS-CoV-2 infection: A possible smart targeting of the autophagy pathway (2020) (77)
- Molecular machinery required for autophagy and the cytoplasm to vacuole targeting (Cvt) pathway in S. cerevisiae. (2002) (75)
- Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. (2005) (75)
- Autophagy and Crohn's disease: at the crossroads of infection, inflammation, immunity, and cancer. (2010) (74)
- In vivo reconstitution of autophagy in Saccharomyces cerevisiae (2008) (73)
- Roles for PI(3,5)P2 in nutrient sensing through TORC1 (2014) (72)
- Receptor protein complexes are in control of autophagy (2012) (72)
- Proteolytic processing of Atg32 by the mitochondrial i-AAA protease Yme1 regulates mitophagy (2013) (72)
- Mitochondria autophagy in yeast. (2011) (71)
- Autophagic degradation of the circadian clock regulator promotes ferroptosis (2019) (71)
- Identification and characterization of a novel yeast gene: the YGP1 gene product is a highly glycosylated secreted protein that is synthesized in response to nutrient limitation. (1994) (71)
- A new class of lysosomal/vacuolar protein sorting signals. (1990) (70)
- AMPK activates autophagy by phosphorylating ULK1. (2011) (69)
- GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis (2011) (69)
- Isolation and characterization of a novel yeast gene, ATH1, that is required for vacuolar acid trehalase activity (1995) (69)
- Nonclassical Protein Sorting to the Yeast Vacuole* (1998) (68)
- Positive or negative roles of different cyclin-dependent kinase Pho85-cyclin complexes orchestrate induction of autophagy in Saccharomyces cerevisiae. (2010) (67)
- Autophagy and inflammation: A special review issue (2018) (67)
- Phosphatidylinositol 4-Kinases Are Required for Autophagic Membrane Trafficking* (2012) (65)
- Atg41/Icy2 regulates autophagosome formation (2015) (65)
- A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsis (2016) (63)
- Inhibiting autophagy reduces retinal degeneration caused by protein misfolding (2018) (62)
- Autophagy is required for zebrafish caudal fin regeneration (2013) (62)
- Escherichia coli mutants defective in the uncH gene (1983) (62)
- The progression of peroxisomal degradation through autophagy requires peroxisomal division (2014) (62)
- Regulation and function of autophagy in pancreatic cancer (2020) (62)
- Ion channels in the regulation of autophagy (2018) (62)
- Resolution of Subunit Interactions and Cytoplasmic Subcomplexes of the Yeast Vacuolar Proton-translocating ATPase (*) (1996) (61)
- Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics. (2021) (61)
- Tumor heterogeneity in autophagy-dependent ferroptosis (2021) (60)
- Phosphorylation of Atg9 regulates movement to the phagophore assembly site and the rate of autophagosome formation (2016) (59)
- Sera from patients with type 2 Diabetes and Neuropathy Induce Autophagy and Colocalization with Mitochondria in SY5Y cells (2005) (59)
- The Golgi as a potential membrane source for autophagy (2010) (58)
- Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine (2020) (57)
- Defining the membrane precursor supporting the nucleation of the phagophore (2014) (56)
- At a Glance: A History of Autophagy and Cancer. (2019) (56)
- Monitoring autophagy in yeast: the Pho8Delta60 assay. (2007) (56)
- Canonical and Noncanonical Autophagy as Potential Targets for COVID-19 (2020) (55)
- Atg9 Trafficking in Autophagy-Related Pathways (2007) (55)
- The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information (1987) (55)
- Differential polypeptide synthesis of the proton-translocating ATPase of Escherichia coli (1982) (54)
- Neurodegeneration: Good riddance to bad rubbish (2006) (54)
- Autophagosome formation: tracing the source. (2013) (54)
- The AMPK-SKP2-CARM1 axis links nutrient sensing to transcriptional and epigenetic regulation of autophagy. (2016) (53)
- Constructing Knowledge in the Lecture Hall. (2002) (52)
- Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo (2018) (52)
- The Fo subunits of the Escherichia coli F1Fo-ATP synthase are sufficient to form a functional proton pore. (1985) (52)
- Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae (1996) (51)
- The yeast Saccharomyces cerevisiae: an overview of methods to study autophagy progression. (2015) (51)
- Crohn's disease, autophagy, and the Paneth cell. (2009) (51)
- Mitochondrial fission facilitates mitophagy in Saccharomyces cerevisiae (2013) (51)
- Estimating the size and number of autophagic bodies by electron microscopy (2014) (51)
- A large-scale analysis of autophagy-related gene expression identifies new regulators of autophagy (2015) (51)
- Protein Transport from the Cytoplasm into the Vacuole (1997) (50)
- A genomic screen for yeast mutants defective in mitophagy (2010) (50)
- Analysis of the native conformation of the LIR/AIM motif in the Atg8/LC3/GABARAP-binding proteins (2015) (50)
- Analyzing autophagy in zebrafish (2010) (50)
- Podocytes and autophagy: a potential therapeutic target in lupus nephritis (2019) (50)
- Autophagy is required for G1/G0 quiescence in response to nitrogen starvation in Saccharomyces cerevisiae (2014) (50)
- Differential effects of compartment deacidification on the targeting of membrane and soluble proteins to the vacuole in yeast. (1994) (49)
- Aberrant Autolysosomal Regulation Is Linked to The Induction of Embryonic Senescence: Differential Roles of Beclin 1 and p53 in Vertebrate Spns1 Deficiency (2014) (48)
- Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha is associated with the yeast vacuole membrane. (1998) (48)
- Atg9 sorting from mitochondria is impaired in early secretion and VFT-complex mutants in Saccharomyces cerevisiae (2006) (48)
- Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase (2017) (47)
- A pathway of targeted autophagy is induced by DNA damage in budding yeast (2017) (47)
- A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae (2018) (47)
- Transport of proteins to the yeast vacuole: autophagy, cytoplasm-to-vacuole targeting, and role of the vacuole in degradation. (2000) (47)
- The autophagy connection. (2010) (46)
- Genetic aberrations in macroautophagy genes leading to diseases. (2018) (46)
- Atg23 and Atg27 Act at the Early Stages of Atg9 Trafficking in S. cerevisiae (2015) (46)
- How to get a folded protein across a membrane. (1999) (45)
- Histone post-translational modifications regulate autophagy flux and outcome (2013) (45)
- The Roles of Ubiquitin in Mediating Autophagy (2020) (45)
- For the last time, it is GFP-Atg8, not Atg8-GFP (and the same goes for LC3) (2011) (44)
- Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response (2022) (43)
- Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging (2017) (43)
- The Atg17-Atg31-Atg29 Complex Coordinates with Atg11 to Recruit the Vam7 SNARE and Mediate Autophagosome-Vacuole Fusion (2016) (42)
- Inflammatory-dependent Sting activation induces antiviral autophagy to limit zika virus in the Drosophila brain (2018) (42)
- Autophagy regulates cytoplasmic remodeling during cell reprogramming in a zebrafish model of muscle regeneration (2016) (42)
- Taking the plunge (2011) (42)
- Points of view: lectures: can't learn with them, can't learn without them. (2004) (41)
- Atg32 Is a tag for mitochondria degradation in yeast (2009) (41)
- Xenophagy: A battlefield between host and microbe, and a possible avenue for cancer treatment (2017) (41)
- Assays for the biochemical and ultrastructural measurement of selective and nonselective types of autophagy in the yeast Saccharomyces cerevisiae. (2015) (41)
- Reconstitution in Vitro of the V1 Complex from the Yeast Vacuolar Proton-translocating ATPase (1997) (40)
- Ksp1 Kinase Regulates Autophagy via the Target of Rapamycin Complex 1 (TORC1) Pathway* (2012) (39)
- Autophagy and Vacuole Homeostasis: A Case for Self-Degradation? (2007) (39)
- Post‐translationally‐modified structures in the autophagy machinery: an integrative perspective (2015) (39)
- Autophagic membrane delivery through ATG9 (2017) (39)
- Dual role of Atg1 in regulation of autophagy-specific PAS assembly in Saccharomyces cerevisiae (2008) (39)
- Permeases Recycle Amino Acids Resulting from Autophagy (2007) (38)
- Transcriptional and post-transcriptional regulation of autophagy in the yeast Saccharomyces cerevisiae (2018) (38)
- In vitro reconstitution of cytoplasm to vacuole protein targeting in yeast (1995) (38)
- TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy (2019) (37)
- Autophagy: mechanism and physiological relevance 'brewed' from yeast studies. (2012) (37)
- Atg27 is a Second Transmembrane Cycling Protein (2007) (37)
- Structural characterization of the Saccharomyces cerevisiae autophagy regulatory complex Atg17-Atg31-Atg29 (2013) (36)
- Atg26 is Not Involved in Autophagy-Related Pathways in Saccharomyces cerevisiae (2007) (35)
- Participation of mitochondrial fission during mitophagy (2013) (34)
- PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex (2018) (34)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Look people, “Atg” is an abbreviation for “autophagy-related.” That’s it. (2012) (33)
- The fungal vacuole: composition, function, and biogenesis (1990) (33)
- Autophagy and SQSTM1 on the RHOA(d) again (2013) (32)
- Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling (2020) (32)
- PHB2/prohibitin 2: An inner membrane mitophagy receptor (2017) (32)
- Identification of Atg3 as an intrinsically disordered polypeptide yields insights into the molecular dynamics of autophagy-related proteins in yeast (2014) (31)
- Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration (2016) (31)
- Increased levels of reduced cytochrome b and mitophagy components are required to trigger nonspecific autophagy following induced mitochondrial dysfunction (2013) (31)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Structure and function of yeast Atg20, a sorting nexin that facilitates autophagy induction (2017) (31)
- Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity (2018) (31)
- Asymmetric Inhibition of Ulk2 Causes Left–Right Differences in Habenular Neuropil Formation (2011) (30)
- Regulation of autophagic lysosome reformation by kinesin 1, clathrin and phosphatidylinositol-4,5-bisphosphate (2018) (30)
- Atg11 Directs Autophagosome Cargoes to the PAS Along Actin Cables (2006) (29)
- Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma (2016) (29)
- Transcriptional regulation of ATG9 by the Pho23-Rpd3 complex modulates the frequency of autophagosome formation (2014) (29)
- Targeting autophagy, oxidative stress, and ER stress for neurodegenerative diseases treatment. (2022) (29)
- Aup 1 p , a Yeast Mitochondrial Protein Phosphatase Homolog , Is Required for Efficient Stationary Phase Mitophagy and Cell Survival * (2007) (29)
- Structures of Atg7-Atg3 and Atg7-Atg10 reveal noncanonical mechanisms of E2 recruitment by the autophagy E1 (2013) (29)
- A Perspective on the Role of Autophagy in Cancer. (2021) (28)
- Autophagy participates in, well, just about everything (2020) (28)
- A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade (2019) (28)
- Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulatory mechanisms (2015) (28)
- Assembly of a functional F1 of the proton-translocating ATPase of Escherichia coli. (1985) (28)
- Mitochondrial abnormalities drive cell death in Wolfram syndrome 2 (2009) (28)
- Autophagy/virophagy: a “disposal strategy” to combat COVID-19 (2020) (27)
- Differential translation of the genes encoding the proton-translocating ATPase of Escherichia coli. (1986) (27)
- Vacuolar ATPase mutants accumulate precursor proteins in a pre-vacuolar compartment. (1993) (27)
- Autophagosome biogenesis requires SNAREs (2011) (27)
- The transmembrane domain of acid trehalase mediates ubiquitin-independent multivesicular body pathway sorting. (2007) (27)
- The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy (2018) (26)
- Double duty of Atg9 self-association in autophagosome biogenesis (2009) (26)
- MAPKs regulate mitophagy in Saccharomyces cerevisiae (2011) (26)
- Activation of autophagy is required for muscle homeostasis during physical exercise (2011) (26)
- A Cooperative Learning Approach To Teaching Introductory Biology. (1998) (26)
- Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer (2021) (26)
- Autophagy is a key factor in maintaining the regenerative capacity of muscle stem cells by promoting quiescence and preventing senescence (2016) (26)
- The molecular machinery of autophagy and its role in physiology and disease. (2010) (26)
- Assembly of a functional F0 of the proton-translocating ATPase of Escherichia coli. (1983) (25)
- A human autophagy interaction network (2012) (25)
- Sex differences in autophagy-mediated diseases: toward precision medicine (2020) (25)
- Dissecting autophagosome formation: The missing pieces (2008) (24)
- Vacuolar hydrolysis and efflux: current knowledge and unanswered questions (2018) (24)
- The Pat1-Lsm Complex Stabilizes ATG mRNA during Nitrogen Starvation-Induced Autophagy. (2019) (24)
- ER stress in Cardiometabolic Diseases: from Molecular Mechanisms to Therapeutics. (2021) (24)
- The emerging mechanisms and functions of microautophagy (2022) (24)
- Autophagy (2005) (23)
- The Importance of Diversity (2007) (23)
- Mutations in the yeast vacuolar ATPase result in the mislocalization of vacuolar proteins. (1992) (23)
- Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection? (2020) (23)
- The Cytoplasm-to-Vacuole Targeting Pathway: A Historical Perspective (2012) (23)
- The vacuole versus the lysosome: when size matters. (2014) (22)
- Indirect estimation of the area density of Atg8 on the phagophore (2009) (22)
- Follicular lymphoma–associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR (2019) (21)
- BRD4 is a newly characterized transcriptional regulator that represses autophagy and lysosomal function (2017) (21)
- Dhh1 promotes autophagy-related protein translation during nitrogen starvation (2019) (21)
- TEX264 is a major receptor for mammalian reticulophagy (2019) (21)
- Signaling pathways in mammalian autophagy (2003) (21)
- Autophagy regulates DNA repair through SQSTM1/p62 (2017) (21)
- Getting into the flow (2008) (21)
- miR-30e Blocks Autophagy and Acts Synergistically with Proanthocyanidin for Inhibition of AVEN and BIRC6 to Increase Apoptosis in Glioblastoma Stem Cells and Glioblastoma SNB19 Cells (2016) (21)
- Overview of Autophagy (2006) (21)
- The quiz factor. (2008) (21)
- A multiple ATG gene knockout strain for yeast two-hybrid analysis (2009) (21)
- DCN released from ferroptotic cells ignites AGER-dependent immune responses (2021) (21)
- The role of autophagy in cardiovascular pathology. (2021) (20)
- The Correct Way to Monitor Autophagy in Higher Eukaryotes (2005) (20)
- A novel role of UBQLNs (ubiquilins) in regulating autophagy, MTOR signaling and v-ATPase function (2020) (20)
- Atg11: a Rab-dependent, coiled-coil membrane protein that acts as a tether for autophagy. (2012) (20)
- The Paf1 complex transcriptionally regulates the mitochondrial-anchored protein Atg32 leading to activation of mitophagy. (2019) (20)
- Secretory autophagy holds the key to lysozyme secretion during bacterial infection of the intestine (2018) (19)
- Autophagy promotes cell motility by driving focal adhesion turnover (2016) (19)
- ER stress in obesity pathogenesis and management. (2021) (19)
- Direct quantification of autophagic flux by a single molecule-based probe (2017) (18)
- Toward an understanding of autophagosome-lysosome fusion: The unsuspected role of ATG14 (2015) (18)
- How cells clean house. (2008) (18)
- Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis (2022) (18)
- Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype? (2020) (18)
- Psp2, a novel regulator of autophagy that promotes autophagy-related protein translation (2019) (18)
- Conserved and unique features of the fission yeast core Atg1 complex (2017) (18)
- The Core Molecular Machinery of Autophagosome Formation (2013) (18)
- Dipeptidyl aminopeptidase processing and biosynthesis of alkaline extracellular protease from Yarrowia lipolytica. (1997) (18)
- Citing recent declines in the discovery of new ATG genes, some scientists now suggest that the end of autophagy research may be within sight (2014) (18)
- Functional impairment in RHOT1/Miro1 degradation and mitophagy is a shared feature in familial and sporadic Parkinson disease (2017) (17)
- Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy (2008) (17)
- Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae. (2010) (16)
- Vacuolar H+-ATPase: From mammals to yeast and back (1996) (16)
- The carboxy terminus of yeast Atg13 binds phospholipid membrane via motifs that overlap with the Vac8-interacting domain (2020) (16)
- Knockdown of PSMB7 Induces Autophagy in Cardiomyocyte Cultures: Possible Role in Endoplasmic Reticulum Stress (2013) (16)
- Stepping back from the guidelines: Where do we stand? (2016) (16)
- Autophagy and neurodegeneration. (2006) (16)
- Alternative protein sorting pathways. (2000) (16)
- Autophagy gets in on the regulatory act. (2011) (15)
- Determining Atg protein stoichiometry at the phagophore assembly site by fluorescence microscopy (2010) (15)
- Developing a set of guidelines for your research field: a practical approach (2016) (15)
- Detection of Saccharomyces cerevisiae Atg13 by western blot (2014) (15)
- Autophagy works out. (2012) (15)
- Signalphagy: scheduled signal termination by macroautophagy. (2013) (14)
- The Ume6-Sin3-Rpd3 complex regulates ATG8 transcription to control autophagosome size (2012) (14)
- The Atg17-Atg31-Atg29 complex and Atg11 regulate autophagosome-vacuole fusion (2016) (14)
- Induction of autophagy-dependent ferroptosis to eliminate drug-tolerant human retinoblastoma cells (2022) (14)
- CCPG1 is a noncanonical autophagy cargo receptor essential for reticulophagy and pancreatic ER proteostasis (2018) (14)
- Cytoplasm to Vacuole Targeting (2003) (14)
- The autophagosome is overrated! (2011) (14)
- Chloroquine in fighting COVID-19: good, bad, or both? (2020) (14)
- Moments in autophagy and disease: Past and present. (2021) (14)
- The molecular mechanism of Atg13 function in autophagy induction: What is hidden behind the data? (2017) (14)
- A novel role for a glycolytic pathway kinase in regulating autophagy has implications in cancer therapy (2017) (14)
- Artophagy: The Art of Autophagy-the Cvt pathway (2010) (14)
- Autophagy in mammalian systems, Part B. Preface. (2009) (14)
- Quantitative regulation of vesicle formation in yeast non-specific autophagy (2008) (14)
- On the relevance of precision autophagy flux control in vivo – Points of departure for clinical translation (2020) (13)
- Nonclassical protein sorting. (1997) (13)
- The Emerging Roles of Autophagy in Human Diseases (2021) (13)
- Atg 27 Is Required for Autophagy-dependent Cycling of Atg 9 (2007) (13)
- Spatially distinct pools of TORC1 balance protein homeostasis (2019) (13)
- Vorinostat in autophagic cell death: a critical insight into autophagy-mediated, -associated and -dependent cell death for cancer prevention. (2021) (13)
- Vac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy (2020) (13)
- Autophagy contributes to lysosomal storage disorders (2012) (13)
- Autophagy: The Potential Link between SARS-CoV-2 and Cancer (2021) (12)
- Faculty Opinions recommendation of Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. (2004) (12)
- In the beginning there was babble… (2012) (12)
- Autophagy in mammalian systems (2009) (12)
- Elevating PI3P drives select downstream membrane trafficking pathways (2020) (12)
- Adaptive immunity at the crossroads of autophagy and metabolism (2021) (12)
- The protective effect of Hif3a RNA interference and HIF‐prolyl hydroxylase inhibition on cardiomyocytes under anoxia‐reoxygenation (2018) (12)
- "Autophagy suite": Atg9 cycling in the cytoplasm to vacuole targeting pathway (2010) (12)
- A multifactorial score including autophagy for prognosis and care of COVID-19 patients (2020) (12)
- Extracellular SQSTM1 as an inflammatory mediator (2020) (12)
- A role for diacylglycerol in antibacterial autophagy (2011) (11)
- Autophagy in age-related macular degeneration (2022) (11)
- An unconventional pathway for mitochondrial protein degradation (2016) (11)
- Why do we need autophagy? A cartoon depiction (2018) (11)
- TOR-dependent post-transcriptional regulation of autophagy (2015) (11)
- The vacuole vs. the lysosome (2014) (11)
- Ion Channels and Transporters in Autophagy (2021) (11)
- Alternative autophagy, brefeldin A and viral trafficking pathways (2016) (11)
- TP53INP2/DOR protein chaperones deacetylated nuclear LC3 to the cytoplasm to promote macroautophagy (2015) (11)
- The proteasome subunit RPN10 functions as a specific receptor for degradation of the 26S proteasome by macroautophagy in Arabidopsis (2016) (11)
- Why do we need to regulate autophagy (and how can we do it)? A cartoon depiction (2018) (10)
- Blame it on Southern, but it's a western blot (2017) (10)
- How Cells Deal with the Fluctuating Environment: Autophagy Regulation under Stress in Yeast and Mammalian Systems (2022) (10)
- The LC3-conjugation machinery specifies cargo loading and secretion of extracellular vesicles (2020) (9)
- Downregulation of autophagy by Met30-mediated Atg9 ubiquitination (2020) (9)
- Life and Death Decisions—The Many Faces of Autophagy in Cell Survival and Cell Death (2022) (9)
- One step closer to understanding mammalian macroautophagy initiation: Interplay of 2 HORMA architectures in the ULK1 complex (2015) (9)
- Artophagy: The art of autophagy—Macroautophagy (2010) (9)
- Allosteric regulation through a switch element in the autophagy E2, Atg3 (2020) (9)
- Melatonin-based therapeutics for atherosclerotic lesions and beyond: Focusing on macrophage mitophagy (2022) (9)
- What Can We Learn from Trypanosomes? (2006) (9)
- TMEM164 is a new determinant of autophagy-dependent ferroptosis (2022) (9)
- The symphony of autophagy and calcium signaling (2015) (9)
- Membrane binding and homodimerization of Atg16 via two distinct protein regions is essential for autophagy in yeast. (2021) (8)
- Deciphering the role of autophagy in heart failure (2021) (8)
- Alternative macroautophagy (2010) (8)
- Glucose-Induced Pexophagy in Pichia pastoris (2003) (8)
- Long-distance autophagy (2015) (8)
- Rph1 mediates the nutrient-limitation signaling pathway leading to transcriptional activation of autophagy (2015) (8)
- An Interactive Exercise to Learn Eukaryotic Cell Structure & Organelle Function (1999) (8)
- New insights into autophagy using a multiple knockout strain (2008) (8)
- The amino acid transporter SLC38A9 regulates MTORC1 and autophagy (2015) (7)
- A Systems Biology Approach to Learning Autophagy (2006) (7)
- On the edge of degradation: Autophagy regulation by RNA decay (2019) (7)
- Keeping the engine clean (2013) (7)
- The role of autophagy in the pathogenesis of SARS-CoV-2 infection in different cell types (2021) (7)
- Regulation of JMY’s actin nucleation activity by TTC5/STRAP and LC3 during autophagy (2019) (7)
- Harpooning the Cvt complex to the phagophore assembly site (2008) (7)
- Proteinase protection of prApe1 as a tool to monitor Cvt vesicle/autophagosome biogenesis (2012) (7)
- Autophagy in disease and clinical applications (2009) (7)
- A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation (2021) (7)
- Copper-dependent autophagic degradation of GPX4 drives ferroptosis. (2023) (7)
- Old factors, new players: transcriptional regulation of autophagy (2020) (7)
- A few key points about figure presentation (2015) (7)
- New tricks of an old autophagy regulator: AMPK-dependent regulation of autophagy through CCNY (cyclin Y)-CDK16 (2020) (6)
- Vps34 is a phosphatidylinositol 3-kinase, not a phosphoinositide 3-kinase (2011) (6)
- Endoplasmic Reticulum–Mitochondria Contacts Are Required for Pexophagy in Saccharomyces cerevisiae (2019) (6)
- A unique hairpin-type tail-anchored SNARE starts to solve a long-time puzzle (2013) (6)
- Corrigendum: The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy (2017) (6)
- An Autophagy-Independent Role for ATG41 in Sulfur Metabolism During Zinc Deficiency (2018) (6)
- The role of Atg29 phosphorylation in PAS assembly (2013) (6)
- Bidirectional roles of Dhh1 in regulating autophagy (2019) (6)
- Looking Back on Two Years of Autophagy (2007) (6)
- Plasmodium protein UIS3 protects the parasite from autophagy clearance (2018) (6)
- A missing piece of the puzzle: Atg11 functions as a scaffold to activate Atg1 for selective autophagy (2015) (6)
- Autophagy regulation by RNA alternative splicing and implications in human diseases (2022) (6)
- Signalphagy (2013) (6)
- SNARE Dance (2012) (6)
- How bacteria can block xenophagy: an insight from Salmonella (2020) (5)
- Autophagy and Vacuole Homeostasis (2007) (5)
- Dimerization-dependent membrane tethering by Atg23 is essential for yeast autophagy (2022) (5)
- Follicular lymphoma-associated mutations in the V-ATPase chaperone VMA21 activate autophagy creating a targetable dependency (2022) (5)
- Post-transcriptional regulation of ATG1 is a critical node that modulates autophagy during distinct nutrient stresses (2021) (5)
- The Ras/PKA signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae (2004) (5)
- New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways (2022) (5)
- The transcription factor Spt4-Spt5 complex regulates the expression of ATG8 and ATG41 (2019) (5)
- MitoPho8Δ60 Assay as a Tool to Quantitatively Measure Mitophagy Activity. (2018) (5)
- Multiple structural rearrangements mediated by high-plasticity regions in Atg3 are key for efficient conjugation of Atg8 to PE during autophagy (2021) (5)
- Ancient autophagy (2013) (5)
- Molecular dynamics simulations reveal how the reticulon-homology domain of the autophagy receptor RETREG1/FAM134B remodels membranes for efficient selective reticulophagy (2020) (5)
- Crohn disease and autophagy (2009) (4)
- The curious case of polyamines: spermidine drives reversal of B cell senescence (2019) (4)
- Autophagy: research topic, painting, poem, dance… (2015) (4)
- Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis. (2022) (4)
- Yeast mitophagy: Unanswered questions. (2021) (4)
- Open Questions for Harnessing Autophagy-Modulating Drugs in the SARS-CoV-2 War (2020) (4)
- Current opinions on mitophagy in fungi (2022) (4)
- Self-eating with your fingers (2012) (4)
- Chaperone-mediated autophagy: The heretofore untold story of J. Fred “Paulo” Dice (2009) (4)
- Searching for the fountain of autophagy-dependent youth (2012) (4)
- The Norse god of autophagy (2010) (4)
- 2020 Is not that far away, which means it is time for the new guidelines (2019) (4)
- Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases (2022) (4)
- Nutrition acquisition by human immunity, transient overnutrition and the cytokine storm in severe cases of COVID-19 (2021) (4)
- There is more to autophagy than induction (2011) (4)
- Structural basis for extremely strong binding affinity of giant ankyrins to LC3/GABARAP and its application in the inhibition of autophagy (2018) (4)
- A second report from the EMBO conference on autophagy: Mechanism, regulation and selectivity of autophagy (2010) (4)
- A separation that’s for the best: coming together at the PAS (2020) (4)
- Receptors make the pathway choice for protein degradation (2017) (4)
- UIM-UDS: a new interface between ATG8 and its interactors (2019) (4)
- The autophagy community (2012) (4)
- CCT2, a newly identified aggrephagy receptor in mammals, specifically mediates the autophagic clearance of solid protein aggregates (2022) (4)
- Gene essentiality of Tubgcp4: dosage effect and autophagy regulation in retinal photoreceptors (2019) (4)
- Early Secretory Pathway Gene TRS85 is Required for Selective Macroautophagy of Peroxisomes in Yarrowia lipolytica (2005) (3)
- An intrinsically disordered protein region encoded by the human disease gene CLEC16A regulates mitophagy (2022) (3)
- Clinical research and Autophagy (2014) (3)
- Phosphorylation of ULK1 serine 746 dictates ATG5-independent autophagy (2020) (3)
- NPC-phagy: selective autophagy of the nuclear pore complexes (2020) (3)
- Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy (2019) (3)
- Analysis of autophagosome membrane cycling by fluorescence microscopy. (2008) (3)
- Why just eat in, when you can also eat out? (2013) (3)
- An autophagy glossary (2010) (3)
- Seeking punctuation clarity—that is, the proper use of the hyphen and dashes—for publishing in Autophagy (2016) (3)
- HS1BP3 provides a novel mechanism of negative autophagy regulation through membrane lipids (2017) (3)
- mTORC1 maintains metabolic balance (2015) (3)
- Yel 013 p ( Vac 8 p ) , an armadillo repeat protein related to plakoglobin and importin α , is associated with the yeast vacuole membrane (1998) (3)
- An AMPK-ULK1-PIKFYVE signaling axis for PtdIns5P-dependent autophagy regulation upon glucose starvation (2021) (3)
- Finding a ribophagy receptor (2018) (3)
- Macromusophagy: A solo piano musical representation of macroautophagy. (2014) (3)
- SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome–lysosome fusion (2022) (3)
- Downregulation of autophagy through CUL3-KLHL20-mediated turnover of the ULK1 and PIK3C3/VPS34 complexes (2016) (3)
- Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations (2018) (3)
- Letter to the Editor The Quiz Factor (2008) (2)
- TOS-sing aside the glycolytic role of HK2/hexokinase-II to activate autophagy (2015) (2)
- Autophagy : lower eukaryotes and non-mammalian systems (2008) (2)
- How Selective is Autophagy? (2006) (2)
- Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment. (2022) (2)
- The DNA Damage Response Induces Autophagy via Mec1(ATR) and Tel1(ATM) to Regulate the Initiation of Anaphase (2015) (2)
- ATG4-family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system (2021) (2)
- Education is the Only Business Where the Customer is Satisfied with Less of the Product (2017) (2)
- Lysosome signaling in cell survival and programmed cell death for cellular homeostasis (2022) (2)
- A pioneer in the field of autophagy microscopy (2013) (2)
- Let’s Not Forget about Non-Specific Autophagy (2006) (2)
- Skn 1 and Ipt 1 negatively regulateautophagy in Saccharomyces cerevisiae (2010) (2)
- Faculty Opinions recommendation of Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes. (2011) (2)
- Erratum: Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways (Molecular Biology of the Cell (1999) 10 (1337-1351)) (1999) (2)
- Intermittent time-restricted feeding promotes longevity through circadian autophagy (2022) (2)
- Tor-dependent post-transcriptional regulation of autophagy: Implications for cancer therapeutics (2016) (2)
- The role of transcriptional ‘futile cycles’ in autophagy and microbial pathogenesis (2015) (2)
- The Spt4 component of the Spt4-Spt5 transcription factor complex negatively regulates the expression of ATG41. (2019) (2)
- Protocols, Toolboxes and Resource papers (2012) (2)
- Location, location, location? No. Catalog number (2009) (2)
- Finding autophagy (2013) (2)
- New insights into MTORC1 amino acid sensing and activation. (2017) (2)
- Identification and characterization of a novel yeast gene: the YGP1 gene product is a highly glycosylated secreted protein that is synthesized in response to nutrient limitation (1994) (2)
- Molecular Process and Physiological Significance of Mitophagy (2014) (2)
- Atg11 (2012) (2)
- Macromusophagy (2014) (2)
- New thoughts regarding Atg8 and ubiquitination (2011) (2)
- The coordination of V-ATPase and ATG16L1 is part of a common mechanism of non-canonical autophagy (2022) (1)
- CLU (clusterin) promotes mitophagic degradation of MSX2 through an AKT-DNM1L/Drp1 axis to maintain SOX2-mediated stemness in oral cancer stem cells. (2023) (1)
- The Pat1-Lsm complex prevents 3′ to 5′ degradation of a specific subset of ATG mRNAs during nitrogen starvation-induced autophagy (2019) (1)
- The phagophore in four dimensions—a study in wood (2018) (1)
- Following your interests: The importance of good mentors (2014) (1)
- Does relevancy matter? (2017) (1)
- Lifeguard Final Exam—Encouraging the Use of Active Learning (2015) (1)
- Bidirectional roles of the Ccr4-Not complex in regulating autophagy before and after nitrogen starvation (2022) (1)
- Do you want to read about a biochemic and genetical analysis of the physiologic role of the autophagical process? No (2012) (1)
- Abstract 4153: Therapeutic targeting autophagy to sensitize cancer immunotherapy in various cancer types (2019) (1)
- The Yeast Vacuole: A Paradigm for Plant Cell Biologists? (2018) (1)
- Daniel Klionsky: A full plate for autophagy. Interview by Ben Short. (2010) (1)
- The “found-art vacuole”—people learn in different ways (2019) (1)
- Autophagy and gene therapy combine in the treatment of liver disease (2013) (1)
- Incomplete mitophagy in the mevalonate kinase-deficient Saccharomyces cerevisiae and its relation to the MKD-related autoinflammatory disease in humans. (2020) (1)
- What were you thinking?: Do not manipulate those data (2010) (1)
- A reagent forum (2008) (1)
- The necessity of nucleophagic modality (2021) (1)
- A “short-cut” response of autophagy to oxidative stress: oxygen-dependent activity of a lysine demethylase guides the activity of ULK1 during hypoxia (2022) (1)
- The Function of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable In Vivo (2017) (1)
- Autophagy in Fungi and Mammals (2004) (1)
- Artophagy (2010) (1)
- When acidic residues do not mimic phosphorylation: high-affinity binding of the reticulophagy receptor TEX264 to LC3/GABARAP (2022) (1)
- Autophagy and Immunity (2014) (1)
- The RB1CC1 Claw-binding motif: a new piece in the puzzle of autophagy regulation (2022) (1)
- Look youse guys and gals, dat just ain’t right (2021) (1)
- Faculty Opinions recommendation of Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. (2006) (1)
- From the urea cycle to autophagy: Alfred J. Meijer (2011) (1)
- A novel reticulophagy receptor, Epr1: a bridge between the phagophore protein Atg8 and ER transmembrane VAP proteins (2020) (1)
- The expanding role of Atg8 (2021) (1)
- Scission, a critical step in autophagosome formation. (2020) (1)
- New regulators of PRKN-independent mitophagy (2021) (1)
- The human disease gene CLEC16A encodes an intrinsically disordered protein region required for mitochondrial quality control (2021) (1)
- The world’s first (and probably last) autophagy video game (2022) (1)
- Quiltophagy—autophagy as folk art (2015) (1)
- An atypical BAR domain protein in autophagy (2018) (1)
- Wait, can you remind me just why we need another journal focused on autophagy? (2022) (1)
- Autophagy under construction: insights from in vitro reconstitution of autophagosome nucleation (2020) (1)
- A PCR analysis of the ubiquitin-like conjugation systems in macroautophagy (2011) (1)
- Autophagy in the retinal pigment epithelium: Insights into age-related macular degeneration (2014) (0)
- Achieve fame and (save your lab a) fortune! (2008) (0)
- The lighter side (2003) (0)
- Faculty Opinions recommendation of USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin. (2014) (0)
- J. Fred “Paulo” Dice: In memoriam (2010) (0)
- Crystal structure of Atg7 NTD K14A F16A D18A mutant (2012) (0)
- From misfolding to autophagy and disease (2015) (0)
- Autophagic structures revealed by cryo-electron tomography: New clues about autophagosome biogenesis. (2023) (0)
- Manipulating Autophagic Degradation in Human Diseases: from Mechanisms to Interventions (2022) (0)
- Membraneprotein sorting: biosynthesis, transportand processing ofyeastvacuolar alkaline phosphatase (1989) (0)
- How to Keep Up in an Expanding Field: Addenda (2005) (0)
- How we do business (or, why does it take other journals so long to review your paper?) (2008) (0)
- Mutations in V-ATPase in follicular lymphoma activate autophagic flux creating a targetable dependency (2022) (0)
- Structure of human ATG9A: how holey art thou? (2020) (0)
- Quick Quiz – Is it Really Recall? (2011) (0)
- MoVast2 combined with MoVast1 regulates lipid homeostasis and autophagy in Magnaporthe oryzae. (2023) (0)
- Copper metabolism in cell death and autophagy. (2023) (0)
- Diversity, equity and inclusion in autophagy research (2022) (0)
- A work in progress (2009) (0)
- The puncta enigma (2017) (0)
- Faculty Opinions recommendation of Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. (2008) (0)
- Glycolytic Enzymes Coale sce in G Bodies under Hypoxic Stress Graphical Abstract Highlights (0)
- Faculty Opinions recommendation of Autophagy defends cells against invading group A Streptococcus. (2004) (0)
- Did evolution choose Atg11 as the scaffolding platform beyond selective autophagy? (2021) (0)
- Faculty Opinions recommendation of Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates. (2009) (0)
- MCOLN3/TRPML3 bridges the regulation of autophagosome biogenesis by PtdIns3P and the calcium channel (2022) (0)
- Learning about autophagy (2006) (0)
- A report from the EMBO conference on autophagy (2009) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Research Highlight Autophagy gets in on the regulatory act (2010) (0)
- Autophagy is the key to making chronic wounds acute in skin wound healing. (2023) (0)
- In the autophagy trenches: The early research career of Russell L. Deter (2008) (0)
- Abstract A224: Autophagy and SQSTM1 on the RHOA(d) again. (2013) (0)
- Hitchhiker’s guide through the axon: transport and local translation of Pink1 mRNA support axonal mitophagy (2022) (0)
- Autophagy-Modulating Drugs in the SARS-CoV-2 War Open Questions for Harnessing (2020) (0)
- The Function and Trafficking of Atg 8 during Autophagosome Formation by Zhiping Xie (2008) (0)
- Autophagy, Inflammation, and Metabolism (AIM) Center in its second year (2019) (0)
- The role of autophagy in catabolism of visual transduction proteins (2016) (0)
- The membrane sources of macroautophagy (2013) (0)
- Faculty Opinions recommendation of Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130. (2016) (0)
- As (and when) you like it: on-demand phospholipid synthesis drives phagophore expansion during autophagy (2020) (0)
- Faculty Opinions recommendation of Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway. (2006) (0)
- Upstream open reading frames mediate autophagy-related protein translation (2022) (0)
- The interaction between autophagy, Helicobacter pylori, and gut microbiota in gastric carcinogenesis. (2023) (0)
- The Lighter Side (2017) (0)
- Faculty Opinions recommendation of Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L). (2011) (0)
- Faculty Opinions recommendation of Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells. (2014) (0)
- Faculty Opinions recommendation of Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. (2011) (0)
- Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response (2022) (0)
- The Functional Significance of Intrinsically Disordered Protein Regions Encoded by the Diabetes Gene Clec16A (2019) (0)
- Psp2, a novel regulator of autophagy that promotes autophagy-related protein translation (2019) (0)
- Faculty Opinions recommendation of The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis. (2012) (0)
- Atg23 is a vesicle-tethering protein (2022) (0)
- A role of autophagy in spinocerebellar ataxia—Rare exception or general principle? (2016) (0)
- Explorer SNARE proteins are required for macroautophagy (2017) (0)
- Crystal structure of an Atg7-Atg10 crosslinked complex (2012) (0)
- Abstract 1939: Follicular Lymphoma-associated mutations in the V-ATPase assembly factor VMA21 activate autophagic flux (2021) (0)
- Teaching the telephone book (2018) (0)
- Found art: the yeast vacuole (2019) (0)
- Functional Analyses of V-Atpase Mutations in Follicular Lymphoma (2016) (0)
- Looking Ahead: Online protocols (2009) (0)
- Where is the field of autophagy research heading? (2023) (0)
- Emerging mechanistic insights of selective autophagy in hepatic diseases (2023) (0)
- Letter to editor (1980) (0)
- Opening new doors in autophagy research: Patrice Codogno (2016) (0)
- AutophagosOMES: identification of autophagosomal cargo in CD4+ T cells by proteomics (2022) (0)
- Quantification of Autophagosome Size and Formation Rate by Electron and Fluorescence Microscopy in Baker’s Yeast (2021) (0)
- MAP1A/BLC3? Now I am really confused (2018) (0)
- …But is it an improvement? (2015) (0)
- Autophagy in Caenorhabditis elegans (2003) (0)
- Forward to the Past (2007) (0)
- A separation that’s for the best: coming together at the PAS (2020) (0)
- Faculty Opinions recommendation of AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. (2011) (0)
- Beth Levine in memoriam (2020) (0)
- CUET-ting edge research (2014) (0)
- Not learning how to ride a bike: The lecture approach (2015) (0)
- Follicular lymphoma-associated mutations in the V-ATPase chaperone Vma21 activate autophagy by dysfunctional V-ATPase assembly (2022) (0)
- Cargo recognition and degradation by selective autophagy (2018) (0)
- Faculty Opinions recommendation of In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. (2004) (0)
- Vps13 is Required for Efficient Autophagy in Saccharomyces cerevisiae (2022) (0)
- Intracellular level of S. cerevisiae Rad51 is regulated via proteolysis in a SUMO- and ubiquitin-dependent manner (2022) (0)
- Erwin Knecht—the intelligent and mad, funny and grumpy man of autophagy (2021) (0)
- Cell Death | Autophagy in Fungi and Mammals (2021) (0)
- UIM-UDS: a new interface between ATG8 and its interactors (2019) (0)
- A cause for childhood ataxia Genetic studies uncover a mutation in a widely conserved protein as the cause of a neurological disorder in two brothers. (2016) (0)
- Faculty Opinions recommendation of Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. (2008) (0)
- Not lowering the bar, just providing a step stool (2021) (0)
- Faculty Opinions recommendation of LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. (2007) (0)
- Letter from the Editor (2006) (0)
- An Atlas of the Genetic Variations Linking Dysregulation of Autophagy to Human Diseases: The Missing Environmental Link (2020) (0)
- The intense gravitational attraction of autophagy (2013) (0)
- Autophagy-related transport of API to the vacuole (1998) (0)
- Skn1and Ipt1negatively regulate autophagy in Saccharomycescerevisiae (2010) (0)
- Autophagy and disease: unanswered questions (2020) (0)
- Autophagy plays a key role in cellular reprograming of myocytes during EOM regeneration (2016) (0)
- Towards understanding mRNA-binding protein specificity: lessons from post-transcriptional regulation of ATG mRNA during nitrogen starvation-induced autophagy (2019) (0)
- TRIM8: a double-edged sword in glioblastoma with the power to heal or hurt (2023) (0)
- Putting the upper-division cart before the introductory horse. (2009) (0)
- Letter to the Editor (2015) (0)
- Faculty Opinions recommendation of How to interpret LC3 immunoblotting. (2007) (0)
- Wouter G van Doorn, December 13, 1951–May 16, 2015 (2015) (0)
- A novel role of ATG9A and RB1CC1/FIP200 in mediating cell-death checkpoints to repress TNF cytotoxicity. (2023) (0)
- Highlights from this issue (2012) (0)
- Autophagy core machinery: overcoming spatial barriers in neurons (2016) (0)
- Faculty Opinions recommendation of Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein. (2012) (0)
- Reciprocal regulatory balance within the CLEC16A-RNF41 mitophagy complex depends on an intrinsically disordered protein region. (2023) (0)
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