Daniel Rader
#64,563
Most Influential Person Now
American professor of molecular medicine
Daniel Rader's AcademicInfluence.com Rankings
Daniel Radercomputer-science Degrees
Computer Science
#2231
World Rank
#2324
Historical Rank
#1004
USA Rank
Machine Learning
#116
World Rank
#117
Historical Rank
#39
USA Rank
Database
#208
World Rank
#216
Historical Rank
#101
USA Rank
Artificial Intelligence
#216
World Rank
#221
Historical Rank
#97
USA Rank
Download Badge
Computer Science
Daniel Rader's Degrees
- PhD Computer Science Stanford University
Similar Degrees You Can Earn
Why Is Daniel Rader Influential?
(Suggest an Edit or Addition)According to Wikipedia, Daniel James Rader is an American academic physician and the Seymour Gray Professor of Molecular Medicine in the Perelman School of Medicine at the University of Pennsylvania. He is also the chief of the Perelman School of Medicine's Division of Translational Medicine and Human Genetics and the director of its Preventive Cardiovascular Program. He is recognized for his research into the genetic underpinnings of atherosclerosis and lipoprotein metabolism.
Daniel Rader's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
- Intensive versus moderate lipid lowering with statins after acute coronary syndromes. (2004) (2522)
- Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
- Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes (2006) (2206)
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
- A randomized trial of a low-carbohydrate diet for obesity. (2003) (1785)
- Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. (2011) (1725)
- A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
- Large-scale association analysis identifies new risk loci for coronary artery disease (2012) (1507)
- Assessment of Coronary Artery Disease by Cardiac Computed Tomography: A Scientific Statement From the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiolog (2006) (1297)
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants (2009) (1100)
- A variant in CDKAL1 influences insulin response and risk of type 2 diabetes (2007) (1066)
- New Insights Into the Regulation of HDL Metabolism and Reverse Cholesterol Transport (2005) (1059)
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus (2010) (1048)
- A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction (2007) (1013)
- Resistin Is an Inflammatory Marker of Atherosclerosis in Humans (2005) (918)
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
- Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. (2016) (847)
- Cholesteryl Ester Transfer Protein: A Novel Target for Raising HDL and Inhibiting Atherosclerosis (2003) (815)
- Electron beam computed tomographic coronary calcium scanning: a review and guidelines for use in asymptomatic persons. (1999) (797)
- A common variant on chromosome 9p21 affects the risk of myocardial infarction. (2007) (795)
- Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction (2009) (790)
- Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. (2012) (779)
- Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. (2004) (777)
- Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
- Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes (2007) (765)
- The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm (2008) (765)
- Absence of microsomal triglyceride transfer protein in individuals with abetalipoproteinemia. (1992) (708)
- Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies (2012) (646)
- Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. (2016) (630)
- Meta-analysis and imputation refines the association of 15q25 with smoking quantity (2010) (605)
- Molecular regulation of HDL metabolism and function: implications for novel therapies. (2006) (586)
- Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study (2013) (579)
- Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo. (2007) (575)
- Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. (1999) (558)
- A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium (2009) (551)
- Monogenic hypercholesterolemia: new insights in pathogenesis and treatment. (2003) (546)
- An Inflammatory Cascade Leading to Hyperresistinemia in Humans (2004) (540)
- Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease (2017) (537)
- The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis This work was supported by P01-HL22633 from the NHLBI. Published, JLR Papers in Press, December 8, 2008. (2009) (531)
- A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia (1995) (526)
- Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice (1998) (526)
- HDL and cardiovascular disease (2014) (518)
- Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution (2007) (515)
- Macrophage reverse cholesterol transport: key to the regression of atherosclerosis? (2006) (511)
- Translating molecular discoveries into new therapies for atherosclerosis (2008) (507)
- A novel endothelial-derived lipase that modulates HDL metabolism (1999) (505)
- The Metabolic Syndrome: More Than the Sum of Its Parts? (2003) (494)
- Weight and Metabolic Outcomes After 2 Years on a Low-Carbohydrate Versus Low-Fat Diet (2010) (493)
- Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies (2011) (490)
- Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. (2011) (483)
- The Agenda for Familial Hypercholesterolemia: A Scientific Statement From the American Heart Association. (2015) (477)
- Implementing genomic medicine in the clinic: the future is here (2013) (463)
- Evacetrapib and Cardiovascular Outcomes in High‐Risk Vascular Disease (2017) (462)
- NARC-1/PCSK9 and Its Natural Mutants (2004) (461)
- Overexpression of Apolipoprotein A-I Promotes Reverse Transport of Cholesterol From Macrophages to Feces In Vivo (2003) (453)
- Application of the tandem differential mobility analyzer to studies of droplet growth or evaporation (1986) (448)
- Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease (2016) (434)
- Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
- COX-2-Derived Prostacyclin Confers Atheroprotection on Female Mice (2004) (427)
- Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction (2014) (426)
- Multi-ethnic genome-wide association study for atrial fibrillation (2018) (425)
- Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia (1993) (423)
- A Protein‐Truncating HSD17B13 Variant and Protection from Chronic Liver Disease (2018) (422)
- Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease (2010) (417)
- Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies (2008) (416)
- Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. (2007) (411)
- Permanent Alteration of PCSK9 With In Vivo CRISPR-Cas9 Genome Editing (2014) (397)
- Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study (2015) (391)
- Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
- Genetics of Blood Lipids Among ~300,000 Multi-Ethnic Participants of the Million Veteran Program (2018) (387)
- Pharmacological Activation of Liver X Receptors Promotes Reverse Cholesterol Transport In Vivo (2005) (385)
- A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction (2006) (383)
- CPAP, weight loss, or both for obstructive sleep apnea. (2014) (368)
- The Ability to Promote Efflux Via ABCA1 Determines the Capacity of Serum Specimens With Similar High-Density Lipoprotein Cholesterol to Remove Cholesterol From Macrophages (2010) (365)
- Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice. (1999) (362)
- The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm (2004) (355)
- Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. (2011) (352)
- Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse. (2000) (348)
- Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting (2017) (338)
- Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer (2009) (336)
- Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. (2011) (333)
- Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus. (2007) (329)
- Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo. (2005) (326)
- Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project (2011) (325)
- Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel. (2018) (321)
- Characterization of the lipolytic activity of endothelial lipase. (2002) (320)
- Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (309)
- The roles of different pathways in the release of cholesterol from macrophages Published, JLR Papers in Press, August 29, 2007. (2007) (299)
- Familial hypercholesterolemias: prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. (2011) (297)
- Increased formation of distinct F2 isoprostanes in hypercholesterolemia. (1998) (294)
- High-density lipoproteins: a consensus statement from the National Lipid Association. (2013) (293)
- Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. (2014) (292)
- Inactivating mutations in NPC1L1 and protection from coronary heart disease. (2014) (289)
- The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation. (2001) (287)
- Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
- Inflammatory markers of coronary risk. (2000) (279)
- High-Density Lipoprotein Promotes Endothelial Cell Migration and Reendothelialization via Scavenger Receptor-B Type I (2005) (278)
- ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. (2017) (278)
- NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis. (2018) (276)
- The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice. (1997) (266)
- The not-so-simple HDL story: Is it time to revise the HDL cholesterol hypothesis? (2012) (262)
- Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations (2019) (259)
- Beyond high-density lipoprotein cholesterol levels evaluating high-density lipoprotein function as influenced by novel therapeutic approaches. (2008) (258)
- Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: Evidence for an antiinflammatory role for lipoprotein lipase (2003) (253)
- Absence of 12/15-Lipoxygenase Expression Decreases Lipid Peroxidation and Atherogenesis in Apolipoprotein E—Deficient Mice (2001) (246)
- Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity (2017) (244)
- Effects of Cholesteryl Ester Transfer Protein Inhibition on High-Density Lipoprotein Subspecies, Apolipoprotein A-I Metabolism, and Fecal Sterol Excretion (2005) (243)
- Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation (2017) (243)
- Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. (2012) (238)
- Flaxseed and Cardiovascular Risk Factors: Results from a Double Blind, Randomized, Controlled Clinical Trial (2008) (237)
- Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339 Published, JLR Papers in Press, July 1, 2005. DOI 10.1194/jlr.D500019-JLR200 (2005) (237)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial. (2003) (228)
- Plasma leptin levels are associated with coronary atherosclerosis in type 2 diabetes. (2004) (226)
- Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms (2017) (224)
- The inverse association of plasma lipoprotein(a) concentrations with apolipoprotein(a) isoform size is not due to differences in Lp(a) catabolism but to differences in production rate. (1994) (220)
- Lomitapide and mipomersen: two first-in-class drugs for reducing low-density lipoprotein cholesterol in patients with homozygous familial hypercholesterolemia. (2014) (214)
- Strong synaptic transmission impact by copy number variations in schizophrenia (2010) (213)
- Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism. (2012) (209)
- Deficiency in Inducible Nitric Oxide Synthase Results in Reduced Atherosclerosis in Apolipoprotein E-Deficient Mice (2000) (208)
- patient-oriented and epidemiological research Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients (2008) (208)
- Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection (2020) (208)
- Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo. (2003) (207)
- Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease (2017) (204)
- Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls (2010) (203)
- Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia (2008) (198)
- Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm (2010) (197)
- Measures of Insulin Resistance Add Incremental Value to the Clinical Diagnosis of Metabolic Syndrome in Association With Coronary Atherosclerosis (2004) (197)
- Regulation of reverse cholesterol transport and clinical implications. (2003) (195)
- The low density lipoprotein receptor is not required for normal catabolism of Lp(a) in humans. (1995) (194)
- Effect of Ultra-Stokesian Drag and Particle Interception on Impaction Characteristics (1985) (194)
- ZYMOGEN CLEAVAGE AND EFFECTS ON THE LOW DENSITY LIPOPROTEIN (LDL) RECEPTOR AND LDL CHOLESTEROL (2004) (191)
- Variation in lipoprotein(a) concentrations among individuals with the same apolipoprotein (a) isoform is determined by the rate of lipoprotein(a) production. (1993) (187)
- Effect of antioxidant vitamins on low density lipoprotein oxidation and impaired endothelium-dependent vasodilation in patients with hypercholesterolemia. (1994) (186)
- Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. (2009) (186)
- Overexpression of Secretory Phospholipase A2 Causes Rapid Catabolism and Altered Tissue Uptake of High Density Lipoprotein Cholesteryl Ester and Apolipoprotein A-I* (2000) (184)
- Update on strategies to increase HDL quantity and function (2009) (182)
- Endothelial Lipase Concentrations Are Increased in Metabolic Syndrome and Associated with Coronary Atherosclerosis (2005) (179)
- Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease (2017) (179)
- Increased Atherosclerosis in Mice Lacking Apolipoprotein A-I Attributable to Both Impaired Reverse Cholesterol Transport and Increased Inflammation (2005) (179)
- Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection (2021) (177)
- Sortilin mediates vascular calcification via its recruitment into extracellular vesicles. (2016) (177)
- Relationship of estimated GFR and coronary artery calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study. (2011) (174)
- In vivo metabolism of apolipoprotein A-I on high density lipoprotein particles LpA-I and LpA-I,A-II. (1991) (174)
- Comparison of intensive and moderate lipid lowering with statins after acute coronary symptoms (2004) (174)
- Trials and Tribulations of CETP Inhibitors. (2018) (171)
- Hepatic overexpression of microsomal triglyceride transfer protein (MTP) results in increased in vivo secretion of VLDL triglycerides and apolipoprotein B. (1999) (168)
- Genome-Wide Association Study Identifies a Novel Locus Contributing to Type 2 Diabetes Susceptibility in Sikhs of Punjabi Origin From India (2013) (168)
- Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia and LDL-C of 160 mg/dl or Higher (2016) (167)
- Aerosol Wall Losses in Electrically Charged Chambers (1985) (166)
- Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels. (2016) (164)
- CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans. (2007) (164)
- A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels (2009) (164)
- Cholesterol Efflux Capacity, High-Density Lipoprotein Particle Number, and Incident Cardiovascular Events: An Analysis From the JUPITER Trial (Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin) (2017) (163)
- Cardiovascular protection by ApoE and ApoE-HDL linked to suppression of ECM gene expression and arterial stiffening. (2012) (162)
- Delayed catabolism of high density lipoprotein apolipoproteins A-I and A-II in human cholesteryl ester transfer protein deficiency. (1993) (161)
- Cardiovascular Risk Assessment Based on US Cohort Studies: Findings From a National Heart, Lung, and Blood Institute Workshop (2001) (161)
- Apolipoprotein E Suppresses the Type I Inflammatory Response In Vivo (2005) (161)
- Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. (2013) (160)
- Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial (2015) (159)
- Effects of Pioglitazone on Lipoproteins, Inflammatory Markers, and Adipokines in Nondiabetic Patients with Metabolic Syndrome (2006) (158)
- Residual macrovascular risk in 2013: what have we learned? (2014) (157)
- The effect of deydroepiandrosterone supplementation to symptomatic perimenopausal women on serum endocrine profiles, lipid parameters, and health-related quality of life (1999) (156)
- Treatment Gaps in Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry (2016) (156)
- Longitudinal evaluation and assessment of cardiovascular disease in patients with homozygous familial hypercholesterolemia. (2008) (155)
- Elevated Plasma Lipoprotein(a) in Patients with the Nephrotic Syndrome (1993) (154)
- Statins and Cognitive Function: A Systematic Review†∗ (2014) (153)
- Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. (2014) (150)
- Multiple rare alleles at LDLR and APOA5 confer risk for early-onset myocardial infarction (2014) (147)
- Macrophage sortilin promotes LDL uptake, foam cell formation, and atherosclerosis. (2015) (146)
- Obesity and atherogenic dyslipidemia. (2007) (146)
- Expression of Cholesteryl Ester Transfer Protein in Mice Promotes Macrophage Reverse Cholesterol Transport (2007) (146)
- Loci influencing blood pressure identified using a cardiovascular gene-centric array. (2013) (145)
- Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance. (2010) (144)
- Novel HDL-directed pharmacotherapeutic strategies (2011) (143)
- Candidate Gene Association Resource (CARe): Design, Methods, and Proof of Concept (2010) (143)
- Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function[S] (2011) (142)
- A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease (2011) (141)
- Dose-Dependent Acceleration of High-Density Lipoprotein Catabolism by Endothelial Lipase (2003) (139)
- Identification of Genetic Variants in Endothelial Lipase in Persons With Elevated High-Density Lipoprotein Cholesterol (2002) (139)
- Angptl3 Deficiency Is Associated With Increased Insulin Sensitivity, Lipoprotein Lipase Activity, and Decreased Serum Free Fatty Acids (2013) (139)
- Lipoproteins, macrophage function, and atherosclerosis: beyond the foam cell? (2005) (139)
- Red Yeast Rice for Dyslipidemia in Statin-Intolerant Patients (2009) (138)
- Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis (2017) (137)
- Microsomal Prostaglandin E Synthase-1 Deletion Suppresses Oxidative Stress and Angiotensin II–Induced Abdominal Aortic Aneurysm Formation (2008) (136)
- Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease (2017) (135)
- Effects of Rosiglitazone on Lipids, Adipokines, and Inflammatory Markers in Nondiabetic Patients With Low High-Density Lipoprotein Cholesterol and Metabolic Syndrome (2005) (135)
- Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. (2010) (135)
- Human Secretory Phospholipase A2 Mediates Decreased Plasma Levels of HDL Cholesterol and ApoA-I in Response to Inflammation in Human ApoA-I Transgenic Mice (2002) (134)
- Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study. (2016) (134)
- Illuminating HDL--is it still a viable therapeutic target? (2007) (134)
- Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
- A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. (2011) (133)
- Markedly accelerated catabolism of apolipoprotein A-II (ApoA-II) and high density lipoproteins containing ApoA-II in classic lecithin: cholesterol acyltransferase deficiency and fish-eye disease. (1994) (132)
- A Genome-Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex (2012) (131)
- The power of genetic diversity in genome-wide association studies of lipids (2021) (129)
- Cascade Screening for Familial Hypercholesterolemia and the Use of Genetic Testing. (2017) (128)
- Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis (2020) (127)
- Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis. (2012) (127)
- Genome-wide Association Study of Peripheral Artery Disease in the Million Veteran Program (2019) (125)
- Endothelial Cells Secrete Triglyceride Lipase and Phospholipase Activities in Response to Cytokines as a Result of Endothelial Lipase (2003) (124)
- Hepatic proprotein convertases modulate HDL metabolism. (2007) (124)
- Momentum slip correction factor for small particles in nine common gases (1990) (122)
- The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans. (2008) (122)
- Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci. (2017) (121)
- Coronary artery calcification and cardiovascular risk factors: impact of the analytic approach. (2004) (121)
- Direct simulation Monte Carlo: The quest for speed (2014) (120)
- Whole-genome sequencing reveals host factors underlying critical COVID-19 (2022) (120)
- Renin-angiotensin system and atherothrombotic disease: from genes to treatment. (2003) (120)
- Relation of serum lipids and lipoproteins with progression of CKD: The CRIC study. (2014) (119)
- The effect of PPAR-alpha agonism on apolipoprotein metabolism in humans. (2010) (117)
- Tissue-Specific Liver X Receptor Activation Promotes Macrophage Reverse Cholesterol Transport In Vivo (2009) (117)
- Reduction of Isoprostanes and Regression of Advanced Atherosclerosis by Apolipoprotein E* (2001) (117)
- Niacin Lipid Efficacy Is Independent of Both the Niacin Receptor GPR109A and Free Fatty Acid Suppression (2012) (117)
- Molecular regulation of macrophage reverse cholesterol transport (2007) (117)
- Effect of 2 Psoriasis Treatments on Vascular Inflammation and Novel Inflammatory Cardiovascular Biomarkers: A Randomized Placebo-Controlled Trial (2018) (116)
- Selective Interleukin-12 Synthesis Defect in 12/15-Lipoxygenase-deficient Macrophages Associated with Reduced Atherosclerosis in a Mouse Model of Familial Hypercholesterolemia* (2002) (116)
- The anti-oxidative capacity of high-density lipoprotein is reduced in acute coronary syndrome but not in stable coronary artery disease. (2011) (116)
- Endogenously Produced Endothelial Lipase Enhances Binding and Cellular Processing of Plasma Lipoproteins via Heparan Sulfate Proteoglycan-mediated Pathway* (2003) (115)
- Endothelial Lipase Is Increased In Vivo by Inflammation in Humans (2008) (115)
- Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib. (2015) (115)
- Rapid regression of atherosclerosis induced by liver-directed gene transfer of ApoE in ApoE-deficient mice. (1999) (114)
- Endothelial lipase: a new member of the triglyceride lipase gene family. (2000) (113)
- Abetalipoproteinemia. New insights into lipoprotein assembly and vitamin E metabolism from a rare genetic disease. (1993) (113)
- The effect of dehydroepiandrosterone supplementation to symptomatic perimenopausal women on serum endocrine profiles, lipid parameters, and health-related quality of life. (2000) (111)
- C-Reactive Protein and Coronary Artery Calcification: The Study of Inherited Risk of Coronary Atherosclerosis (SIRCA) (2003) (111)
- Safety and feasibility of liver-directed ex vivo gene therapy for homozygous familial hypercholesterolemia. (1996) (110)
- Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate to severe psoriasis. (2012) (109)
- Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity (2017) (108)
- Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. (2016) (108)
- Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis. (2010) (107)
- Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies (2017) (107)
- Angiopoietin-like Protein 3 Inhibits Lipoprotein Lipase Activity through Enhancing Its Cleavage by Proprotein Convertases* (2010) (107)
- Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis (2015) (106)
- In vivo modulation of HDL phospholipid has opposing effects on SR-BI- and ABCA1-mediated cholesterol efflux Published, JLR Papers in Press, November 1, 2003. DOI 10.1194/jlr.M300231-JLR200 (2004) (106)
- Future Therapeutic Directions in Reverse Cholesterol Transport (2010) (106)
- Effect of transdermal testosterone treatment on serum lipid and apolipoprotein levels in men more than 65 years of age. (2001) (106)
- Jaye, M. et al. A novel endothelial-derived lipase that modulates HDL metabolism. Nat. Genet. 21, 424-428 (1999) (105)
- Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease (2019) (105)
- Laboratory assessment of HDL heterogeneity and function. (2008) (105)
- SARS-CoV-2 seroprevalence among parturient women in Philadelphia (2020) (104)
- Knockout of Adamts7, a Novel Coronary Artery Disease Locus in Humans, Reduces Atherosclerosis in Mice (2015) (102)
- Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. (2012) (101)
- Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport. (2006) (101)
- Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease. (2015) (101)
- Lipases and HDL metabolism (2002) (100)
- Lipoprotein(a). Clinical approach to a unique atherogenic lipoprotein. (1992) (100)
- Statins and Cognitive Function (2013) (99)
- In vivo metabolism of a mutant apolipoprotein, apoA-IIowa, associated with hypoalphalipoproteinemia and hereditary systemic amyloidosis. (1992) (99)
- Apolipoprotein A-I Deficiency Results in Markedly Increased Atherosclerosis in Mice Lacking the LDL Receptor (2003) (99)
- Genetics and Cardiovascular Disease: A Policy Statement From the American Heart Association (2012) (98)
- Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia (2013) (98)
- The triglyceride-high-density lipoprotein axis: an important target of therapy? (2004) (98)
- Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents. (2016) (95)
- Genetic Basis of Atherosclerosis: Insights From Mice and Humans (2012) (95)
- Liver-directed gene transfer and prolonged expression of three major human ApoE isoforms in ApoE-deficient mice. (1997) (94)
- Increased catabolic rate of low density lipoproteins in humans with cholesteryl ester transfer protein deficiency. (1995) (94)
- Accuracy and efficiency of the sophisticated direct simulation Monte Carlo algorithm for simulating noncontinuum gas flows (2009) (94)
- From Darwin's finches to canaries in the coal mine--mining the genome for new biology. (2008) (94)
- Gene therapy with novel adeno‐associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia (2004) (93)
- Safety and effectiveness of Niaspan when added sequentially to a statin for treatment of dyslipidemia. (2001) (93)
- Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a] Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.M500249-JLR200 (2005) (93)
- Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production Published, JLR Papers in Press, July 30, 2006. (2006) (92)
- A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation (2015) (92)
- Emerging role of FDG-PET/CT in assessing atherosclerosis in large arteries (2008) (92)
- Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice. (2008) (91)
- A dose-titration and comparative study of rosuvastatin and atorvastatin in patients with homozygous familial hypercholesterolaemia. (2008) (91)
- Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes (2018) (91)
- A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia. (2017) (90)
- [Laboratory assessment of HDL heterogeneity and function]. (2009) (90)
- Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. (2010) (89)
- A randomized trial of the effects of an almond-enriched, hypocaloric diet in the treatment of obesity1234 (2012) (89)
- Vitamin E dose-response studies in humans with use of deuterated RRR-alpha-tocopherol. (1998) (89)
- A phase III randomized trial evaluating alirocumab 300 mg every 4 weeks as monotherapy or add-on to statin: ODYSSEY CHOICE I. (2016) (89)
- GlycA Is a Novel Biomarker of Inflammation and Subclinical Cardiovascular Disease in Psoriasis. (2016) (88)
- Evaluation of apoA-I kinetics in humans using simultaneous endogenous stable isotope and exogenous radiotracer methods. (1993) (88)
- Proprotein Covertases Are Responsible for Proteolysis and Inactivation of Endothelial Lipase* (2005) (88)
- An experimental assembly for precise measurement of thermal accommodation coefficients. (2011) (87)
- Lecithin: Cholesterol Acyltransferase Expression Has Minimal Effects on Macrophage Reverse Cholesterol Transport In Vivo (2009) (87)
- A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels (2017) (86)
- High-Density Lipoprotein Hydrolysis by Endothelial Lipase Activates PPAR&agr;: A Candidate Mechanism for High-Density Lipoprotein–Mediated Repression of Leukocyte Adhesion (2006) (85)
- Rationale and design of the familial hypercholesterolemia foundation CAscade SCreening for Awareness and DEtection of Familial Hypercholesterolemia registry. (2014) (85)
- ABC1: connecting yellow tonsils, neuropathy, and very low HDL. (1999) (85)
- Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity (2021) (85)
- Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia. (2017) (85)
- Convergence behavior of a new DSMC algorithm (2009) (85)
- Mapping and characterization of structural variation in 17,795 human genomes (2020) (84)
- Defensin stimulates the binding of lipoprotein (a) to human vascular endothelial and smooth muscle cells. (1997) (83)
- HDL Cholesterol Metabolism and the Risk of CHD: New Insights from Human Genetics (2017) (83)
- Dense Genotyping of Candidate Gene Loci Identifies Variants Associated With High-Density Lipoprotein Cholesterol (2011) (82)
- Val64Ile Polymorphism in the C-C Chemokine Receptor 2 Is Associated With Reduced Coronary Artery Calcification (2002) (81)
- Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. (2013) (80)
- Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease. (2017) (79)
- Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin. (2003) (79)
- High-Density Lipoprotein (HDL) Phospholipid Content and Cholesterol Efflux Capacity Are Reduced in Patients With Very High HDL Cholesterol and Coronary Disease (2015) (79)
- Efficacy and Safety of Alirocumab 150 mg Every 4 Weeks in Patients With Hypercholesterolemia Not on Statin Therapy: The ODYSSEY CHOICE II Study (2016) (78)
- The addition of niacin to statin therapy improves high-density lipoprotein cholesterol levels but not metrics of functionality. (2013) (78)
- The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels. (2011) (78)
- Secretory Phospholipase A2-IIA and Cardiovascular Disease (2013) (78)
- Approach to the patient with extremely low HDL-cholesterol. (2012) (77)
- Genomics-First Evaluation of Heart Disease Associated With Titin-Truncating Variants. (2019) (77)
- Complete Deficiency of the Low-Density Lipoprotein Receptor Is Associated With Increased Apolipoprotein B-100 Production (2005) (77)
- A 30-Amino Acid Truncation of the Microsomal Triglyceride Transfer Protein Large Subunit Disrupts Its Interaction with Protein Disulfide-isomerase and Causes Abetalipoproteinemia (*) (1995) (77)
- Endothelial Lipase Promotes the Catabolism of ApoB-Containing Lipoproteins (2004) (77)
- Both the Peroxisome Proliferator‐Activated Receptor δ Agonist, GW0742, and Ezetimibe Promote Reverse Cholesterol Transport in Mice by Reducing Intestinal Reabsorption of HDL‐Derived Cholesterol (2009) (76)
- Role of dietary supplements in lowering low-density lipoprotein cholesterol: a review. (2010) (76)
- Flaxseed Reduces Plasma Cholesterol Levels in Hypercholesterolemic Mouse Models (2007) (76)
- An approach for simulating the transport of spherical particles in a rarefied gas flow via the direct simulation Monte Carlo method (2001) (75)
- Assessment of the clinical effects of cholesteryl ester transfer protein inhibition with evacetrapib in patients at high-risk for vascular outcomes: Rationale and design of the ACCELERATE trial. (2015) (74)
- Effect of interleukin 1&bgr; inhibition in cardiovascular disease (2012) (74)
- Expression of serum amyloid A protein in the absence of the acute phase response does not reduce HDL cholesterol or apoA-I levels in human apoA-I transgenic mice. (1999) (74)
- Differential Association of Plasma Angiopoietin-Like Proteins 3 and 4 With Lipid and Metabolic Traits (2014) (74)
- Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. (2010) (73)
- Effects of the Cholesteryl Ester Transfer Protein Inhibitor Torcetrapib on Apolipoprotein B100 Metabolism in Humans (2006) (72)
- Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. (2015) (72)
- Pharmacologic Suppression of Hepatic ATP-Binding Cassette Transporter 1 Activity in Mice Reduces High-Density Lipoprotein Cholesterol Levels but Promotes Reverse Cholesterol Transport (2011) (72)
- Direct simulation Monte Carlo convergence behavior of the hard-sphere-gas thermal conductivity for Fourier heat flow (2006) (72)
- A randomized study comparing the effects of a low-carbohydrate diet and a conventional diet on lipoprotein subfractions and C-reactive protein levels in patients with severe obesity. (2004) (72)
- Association of the Vitamin D Metabolism Gene CYP24A1 With Coronary Artery Calcification (2010) (71)
- High-density lipoproteins and atherosclerosis. (2002) (71)
- Mechanisms of Disease: HDL metabolism as a target for novel therapies (2007) (71)
- Sortilin and lipoprotein metabolism: making sense out of complexity (2014) (71)
- Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent (2007) (71)
- Posttranscriptional Control of the Expression and Function of Diacylglycerol Acyltransferase-1 in Mouse Adipocytes* (2002) (70)
- Nonstatin Low-Density Lipoprotein–Lowering Therapy and Cardiovascular Risk Reduction—Statement From ATVB Council (2015) (70)
- Apolipoprotein A-II production rate is a major factor regulating the distribution of apolipoprotein A-I among HDL subclasses LpA-I and LpA-I:A-II in normolipidemic humans. (1995) (70)
- Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in mice. (2000) (70)
- Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. (2018) (69)
- Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic/Latino Ancestry. (2019) (69)
- Gene Therapy in a Humanized Mouse Model of Familial Hypercholesterolemia Leads to Marked Regression of Atherosclerosis (2010) (69)
- Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice. (2009) (69)
- The Farnesoid X Receptor A Molecular Link Between Bile Acid and Lipid and Glucose Metabolism (2005) (69)
- Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease. (2018) (68)
- Coronary Artery Calcification in Renal Transplant Recipients (2005) (68)
- Triglyceride-rich lipoproteins and coronary artery disease risk: new insights from human genetics. (2015) (67)
- Future of cholesteryl ester transfer protein inhibitors. (2014) (67)
- Endothelial lipase is associated with inflammation in humans Published, JLR Papers in Press, September 15, 2006. (2006) (66)
- Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease. (2020) (66)
- Impact of Combined Deficiency of Hepatic Lipase and Endothelial Lipase on the Metabolism of Both High-Density Lipoproteins and Apolipoprotein B–Containing Lipoproteins (2010) (66)
- High‐Density Lipoproteins in the Prevention of Cardiovascular Disease: Changing the Paradigm (2014) (65)
- Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci (2018) (65)
- The alpha-defensins stimulate proteoglycan-dependent catabolism of low-density lipoprotein by vascular cells: a new class of inflammatory apolipoprotein and a possible contributor to atherogenesis. (2000) (65)
- New Therapeutic Approaches to the Treatment of Dyslipidemia. (2016) (65)
- Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia. (2013) (65)
- A Study of the Effects of Anisokinetic Sampling (1988) (65)
- Rosuvastatin improves the atherogenic and atheroprotective lipid profiles in patients with hypertriglyceridemia (2004) (65)
- Genetic polymorphism of human plasma apolipoprotein A-IV is due to nucleotide substitutions in the apolipoprotein A-IV gene. (1990) (65)
- A saturated map of common genetic variants associated with human height (2022) (65)
- Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα. (2015) (64)
- Genetic analysis for a shared biological basis between migraine and coronary artery disease (2015) (64)
- Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease (2017) (64)
- Unravelling high density lipoprotein-apolipoprotein metabolism in human mutants and animal models (1996) (64)
- Plasma Apolipoprotein C-III Levels, Triglycerides, and Coronary Artery Calcification in Type 2 Diabetics (2015) (63)
- Macrophage Reverse Cholesterol Transport in Mice Expressing ApoA-I Milano (2009) (63)
- High density lipoprotein cholesterol and cancer: Marker or causative? (2018) (62)
- Antioxidant therapy and atherosclerosis: animal and human studies. (2001) (61)
- Finding missed cases of familial hypercholesterolemia in health systems using machine learning (2019) (61)
- High-density lipoproteins as an emerging therapeutic target for atherosclerosis. (2003) (61)
- Effects of Nonlipolytic Ligand Function of Endothelial Lipase on High Density Lipoprotein Metabolism in Vivo* (2003) (60)
- Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study (2016) (60)
- Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha. (2005) (59)
- Microsomal transfer protein inhibition in humans (2013) (59)
- Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals (2021) (59)
- Biomarkers of Calcific Aortic Valve Disease (2017) (59)
- Does exercise increase HDL cholesterol in those who need it the most? (2001) (58)
- Comparison of Coronary Artery Calcium Scores Between Patients With Psoriasis and Type 2 Diabetes. (2016) (58)
- TTC39B Deficiency Stabilizes LXR Reducing both Atherosclerosis and Steatohepatitis (2016) (58)
- Adipocyte enhancer-binding protein 1 is a potential novel atherogenic factor involved in macrophage cholesterol homeostasis and inflammation (2006) (58)
- Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes. (2010) (58)
- Phenotypic extremes in rare variant study designs (2015) (58)
- Evaporation rates of monodisperse organic aerosols in the 0.02- to 0.2-μm-diameter range (1987) (58)
- Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor. (2000) (57)
- Normal solutions of the Boltzmann equation for highly nonequilibrium Fourier flow and Couette flow (2005) (57)
- Two different allelic mutations in the lecithin:cholesterol acyltransferase (LCAT) gene resulting in classic LCAT deficiency: LCAT (tyr83-->stop) and LCAT (tyr156-->asn). (1993) (57)
- Long‐term effects of LDL apheresis in patients with severe hypercholesterolemia (2005) (56)
- A Gaussian copula approach for the analysis of secondary phenotypes in case-control genetic association studies. (2012) (56)
- From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease. (2016) (56)
- Decreased cholesterol efflux capacity and atherogenic lipid profile in young women with PCOS. (2014) (55)
- Liver X receptor and farnesoid X receptor as therapeutic targets. (2007) (55)
- Gas-phase nanoparticle formation and transport during pulsed laser deposition of Y1Ba2Cu3O7−d (1999) (55)
- APS Response to Nonspherical Particles and Experimental Determination of Dynamic Shape Factor (1990) (54)
- Biochemical characterization of the three major subclasses of lipoprotein A-I preparatively isolated from human plasma. (1993) (54)
- HDL-cholesterol and cardiovascular disease: rethinking our approach (2015) (54)
- Endothelial lipase: a modulator of lipoprotein metabolism upregulated by inflammation. (2004) (54)
- Evidence that endothelial lipase remodels high density lipoproteins without mediating the dissociation of apolipoprotein A-I Published, JLR Papers in Press, February 1, 2005. DOI 10.1194/jlr.M400212-JLR200 (2005) (53)
- In vivo metabolism of apolipoprotein A-I in a patient with homozygous familial hypercholesterolemia. (1992) (53)
- Peroxisome Proliferator-Activated Receptor-&agr; Activation Promotes Macrophage Reverse Cholesterol Transport Through a Liver X Receptor–Dependent Pathway (2011) (53)
- Discrimination between RRR- and all-racemic-alpha-tocopherols labeled with deuterium by patients with abetalipoproteinemia. (1994) (53)
- Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue. (2005) (53)
- Increased production of apolipoprotein A-I associated with elevated plasma levels of high-density lipoproteins, apolipoprotein A-I, and lipoprotein A-I in a patient with familial hyperalphalipoproteinemia. (1993) (52)
- Genetic Ablation of Adamts13 Gene Dramatically Accelerates the Formation of Early Atherosclerosis in a Murine Model (2012) (52)
- Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide* (2015) (52)
- Increased Protein Nitration Burden in the Atherosclerotic Lesions and Plasma of Apolipoprotein A-I–Deficient Mice (2007) (52)
- Anti‐oxidative and cholesterol efflux capacities of high‐density lipoprotein are reduced in ischaemic cardiomyopathy (2013) (52)
- Molecular gas dynamics observations of Chapman-Enskog behavior and departures there from in nonequilibrium gases. (2004) (51)
- Markedly increased secretion of VLDL triglycerides induced by gene transfer of apolipoprotein E isoforms in apoE-deficient mice. (2000) (51)
- Gene-Centric Meta-Analysis of Lipid Traits in African, East Asian and Hispanic Populations (2012) (51)
- CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects (2017) (51)
- Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort). (2013) (51)
- Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation. (2004) (50)
- US physician practices for diagnosing familial hypercholesterolemia: data from the CASCADE-FH registry. (2016) (50)
- Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice. (1998) (50)
- Fish Oil Promotes Macrophage Reverse Cholesterol Transport in Mice (2009) (50)
- Pathways by Which Reconstituted High-Density Lipoprotein Mobilizes Free Cholesterol From Whole Body and From Macrophages (2010) (50)
- Determinants of Coronary Artery Calcification Progression in Renal Transplant Recipients (2007) (49)
- The Evolution and Refinement of Traditional Risk Factors for Cardiovascular Disease (2012) (49)
- Complete Prevention of Atherosclerosis in ApoE-Deficient Mice by Hepatic Human ApoE Gene Transfer With Adeno-Associated Virus Serotypes 7 and 8 (2006) (49)
- Effects of niacin, statin, and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 levels in patients with dyslipidemia. (2015) (49)
- Molecular Mechanisms Responsible for the Differential Effects of ApoE3 and ApoE4 on Plasma Lipoprotein–Cholesterol Levels (2013) (49)
- Hepatic protein phosphatase 1 regulatory subunit 3B (Ppp1r3b) promotes hepatic glycogen synthesis and thereby regulates fasting energy homeostasis (2017) (49)
- CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease. (2019) (49)
- Overexpression of Apolipoprotein F Reduces HDL Cholesterol Levels In Vivo (2009) (49)
- Wild-Type ApoA-I and the Milano Variant Have Similar Abilities to Stimulate Cellular Lipid Mobilization and Efflux (2007) (49)
- Reducing the burden of disease and death from familial hypercholesterolemia: a call to action. (2014) (49)
- Hepatic expression of apolipoprotein E inhibits progression of atherosclerosis without reducing cholesterol levels in LDL receptor-deficient mice. (2000) (48)
- CXCL12: a new player in coronary disease identified through human genetics. (2010) (48)
- Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for LDLR and Myocardial Infarction (2015) (48)
- mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion (2017) (48)
- Sortilin as a Regulator of Lipoprotein Metabolism (2012) (48)
- Noninvasive atherosclerosis imaging for predicting cardiovascular events and assessing therapeutic interventions (2004) (48)
- Evidence that hepatic lipase and endothelial lipase have different substrate specificities for high-density lipoprotein phospholipids. (2003) (47)
- Oral Apolipoprotein A‐I Mimetic D‐4F Lowers HDL‐Inflammatory Index in High‐Risk Patients: A First‐in‐Human Multiple‐Dose, Randomized Controlled Trial (2017) (47)
- Polygenic determinants in extremes of high-density lipoprotein cholesterol[S] (2017) (47)
- Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project (2012) (47)
- AAV Vectors Expressing LDLR Gain-of-Function Variants Demonstrate Increased Efficacy in Mouse Models of Familial Hypercholesterolemia (2014) (47)
- Plasma Cytokines, Metabolic Syndrome, and Atherosclerosis in Humans (2007) (47)
- Genes influencing HDL metabolism: new perspectives and implications for atherosclerosis prevention. (2000) (46)
- Effect of Access to Prescribed PCSK9 Inhibitors on Cardiovascular Outcomes (2019) (46)
- Identification of the Active Form of Endothelial Lipase, a Homodimer in a Head-to-Tail Conformation* (2009) (46)
- Expression of Human Hepatic Lipase in the Rabbit Model Preferentially Enhances the Clearance of Triglyceride‐Enriched Versus Native High‐Density Lipoprotein Apolipoprotein A‐I (2003) (46)
- The role of endothelial lipase in high-density lipoprotein metabolism (2004) (46)
- Health disparities among adult patients with a phenotypic diagnosis of familial hypercholesterolemia in the CASCADE-FH™ patient registry. (2017) (46)
- Higher plasma CXCL12 levels predict incident myocardial infarction and death in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort study. (2014) (46)
- The endothelium and lipoproteins: insights from recent cell biology and animal studies. (2000) (46)
- Substrate specificity of lipoprotein lipase and endothelial lipase: studies of lid chimeras Published, JLR Papers in Press, May 10, 2006. (2006) (46)
- COVID-19 outcomes and the human genome (2020) (46)
- Regulated expression of endothelial lipase by porcine brain capillary endothelial cells constituting the blood–brain barrier (2005) (45)
- Association of Traditional Risk Factors With Coronary Calcification in Persons With a Family History of Premature Coronary Heart Disease (2001) (45)
- Translational studies of lipoprotein-associated phospholipase A₂ in inflammation and atherosclerosis. (2012) (45)
- Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations (2019) (45)
- Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry. (2019) (45)
- Three genetic variants of human plasma apolipoprotein A-IV. apoA-IV-1(Thr347----Ser), apoA-IV-0(Lys167----Glu,Gln360----His), and apoA-IV-3(Glu165----Lys). (1991) (45)
- Apolipoprotein(a) deposition in atherosclerotic plaques of cerebral vessels. A potential role for endothelial cells in lesion formation. (1995) (45)
- Lipase H, a new member of the triglyceride lipase family synthesized by the intestine. (2002) (44)
- Exome Sequencing in Suspected Monogenic Dyslipidemias (2015) (44)
- Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects. (2016) (44)
- IL-1 and atherosclerosis: a murine twist to an evolving human story. (2012) (44)
- Adiponectin is associated with favorable lipoprotein profile, independent of BMI and insulin resistance, in adolescents. (2011) (44)
- Role of fibrates in the management of hypertriglyceridemia. (1999) (43)
- On-statin cholesteryl ester transfer protein mass and risk of recurrent coronary events (from the pravastatin or atorvastatin evaluation and infection therapy-thrombolysis in myocardial infarction 22 [PROVE IT-TIMI 22] study). (2010) (43)
- The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. (2009) (42)
- MDR and PRP: A Comparison of Methods for High-Order Genotype-Phenotype Associations (2005) (42)
- Correcting population stratification in genetic association studies using a phylogenetic approach (2010) (42)
- Lipoproteins as Biomarkers and Therapeutic Targets in the Setting of Acute Coronary Syndrome (2014) (42)
- Association of APOC3 Loss-of-Function Mutations With Plasma Lipids and Subclinical Atherosclerosis: The Multi-Ethnic BioImage Study. (2015) (42)
- Rapid in vivo transport and catabolism of human apolipoprotein A-IV-1 and slower catabolism of the apoA-IV-2 isoprotein. (1993) (42)
- The frequency of the cholesteryl ester transfer protein-TaqI B2 allele is lower in African Americans than in Caucasians. (2002) (41)
- Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program (2020) (41)
- Mining the Stiffness-Sensitive Transcriptome in Human Vascular Smooth Muscle Cells Identifies Long Noncoding RNA Stiffness Regulators (2018) (41)
- Psoriasis is associated with decreased plasma adiponectin levels independently of cardiometabolic risk factors (2014) (41)
- Acute inflammation increases selective uptake of HDL cholesteryl esters into adrenals of mice overexpressing human sPLA2. (2003) (41)
- Endothelial Lipase Is a Critical Determinant of High-Density Lipoprotein–Stimulated Sphingosine 1-Phosphate–Dependent Signaling in Vascular Endothelium (2013) (41)
- Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions (2017) (41)
- S447X variant of the lipoprotein lipase gene, lipids, and risk of coronary heart disease in 3 prospective cohort studies. (2009) (41)
- Lipases as modulators of atherosclerosis in murine models. (2007) (40)
- Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease (2022) (40)
- Human plasma apolipoproteins A-IV-0 and A-IV-3. Molecular basis for two rare variants of apolipoprotein A-IV-1. (1990) (40)
- Lipids, Apolipoproteins, and Risk of Atherosclerotic Cardiovascular Disease in Persons With CKD. (2019) (40)
- Normal Production Rate of Apolipoprotein B in LDL Receptor–Deficient Mice (2002) (40)
- Human genetics of variation in high-density lipoprotein cholesterol (2006) (40)
- Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia. (2016) (39)
- Influence of Apolipoprotein A-I Domain Structure on Macrophage Reverse Cholesterol Transport in Mice (2011) (39)
- Panstromal Schnyder's corneal dystrophy. Ultrastructural and histochemical studies. (1992) (39)
- A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes (2019) (39)
- Potent and Selective PPAR-α Agonist LY518674 Upregulates Both ApoA-I Production and Catabolism in Human Subjects With the Metabolic Syndrome (2009) (39)
- Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis (2016) (39)
- Decreased plasma levels of lipoprotein(a) in patients with hypertriglyceridemia. (1994) (39)
- 12/15-Lipoxygenase gene disruption and vitamin E administration diminish atherosclerosis and oxidative stress in apolipoprotein E deficient mice through a final common pathway. (2005) (39)
- In vivo metabolism of apolipoproteins A-I and E in patients with abetalipoproteinemia: implications for the roles of apolipoproteins B and E in HDL metabolism. (1994) (39)
- Lipoprotein(a) and Risk of Myocardial Infarction and Death in Chronic Kidney Disease: Findings From the CRIC Study (Chronic Renal Insufficiency Cohort) (2017) (39)
- A Novel Generalized Lipodystrophy-Associated Progeroid Syndrome Due to Recurrent Heterozygous LMNA p.T10I Mutation (2018) (39)
- Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. (2017) (39)
- Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors (2019) (39)
- Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects. (2015) (38)
- Cardiovascular disease: The diet–microbe morbid union (2011) (38)
- Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR+/- Rhesus Macaques. (2017) (38)
- Serum Fractalkine (CX3CL1) and Cardiovascular Outcomes and Diabetes: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. (2015) (38)
- Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes. (2021) (38)
- Adipose Modulation of High-Density Lipoprotein Cholesterol: Implications for Obesity, High-Density Lipoprotein Metabolism, and Cardiovascular Disease (2011) (38)
- Visceral adiposity and endothelial lipase. (2006) (38)
- SARS-CoV-2 Seroprevalence Among Parturient Women (2020) (38)
- Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress. (2017) (37)
- Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice. (2011) (37)
- Diabetes reduces bone marrow and circulating porcine endothelial progenitor cells, an effect ameliorated by atorvastatin and independent of cholesterol (2009) (37)
- The lipid-lowering effects of lomitapide are unaffected by adjunctive apheresis in patients with homozygous familial hypercholesterolaemia - a post-hoc analysis of a Phase 3, single-arm, open-label trial. (2015) (37)
- Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing (2016) (36)
- Deep RNA Sequencing Uncovers a Repertoire of Human Macrophage Long Intergenic Noncoding RNAs Modulated by Macrophage Activation and Associated With Cardiometabolic Diseases (2017) (36)
- CD59 but not DAF deficiency accelerates atherosclerosis in female ApoE knockout mice. (2009) (36)
- Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase. (2005) (36)
- Robust passive and active efflux of cellular cholesterol to a designer functional mimic of high density lipoprotein (2015) (36)
- Associations between cardiovascular disease, cancer, and very low high-density lipoprotein cholesterol in the REasons for Geographical and Racial Differences in Stroke (REGARDS) study (2018) (36)
- Large-scale genome-wide association study of coronary artery disease in genetically diverse populations (2022) (36)
- Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol (2011) (36)
- ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia—Brief Report (2021) (36)
- Effects of nonstatin lipid drug therapy on high-density lipoprotein metabolism. (2003) (36)
- High-density lipoprotein metabolism: Molecular targets for new therapies for atherosclerosis (2000) (35)
- Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function. (2020) (35)
- Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia. (2013) (35)
- Targeting High Density Lipoproteins in the Prevention of Cardiovascular Disease? (2012) (35)
- Pharmacological management of high triglycerides and low high-density lipoprotein cholesterol. (2001) (35)
- HDL re-examined (2015) (35)
- Gender differences in the association of C‐reactive protein with coronary artery calcium in Type‐2 diabetes (2011) (35)
- Investigation of lipoprotein kinetics using endogenous labeling with stable isotopes (1992) (35)
- Correlation of apolipoprotein(a) isoproteins with Lp(a) density and distribution in fasting plasma. (1992) (35)
- Metabolic Syndrome, Components, and Cardiovascular Disease Prevalence in Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study (2011) (34)
- Cholesterol efflux capacity: full steam ahead or a bump in the road? (2013) (34)
- Comparison of human apoA-I expression in mouse models of atherosclerosis after gene transfer using a second generation adenovirus. (1997) (34)
- Thermophoresis in Rarefied Gas Flows (2002) (34)
- Targeting the Coronavirus Nucleocapsid Protein through GSK-3 Inhibition (2021) (34)
- Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. (2016) (34)
- Teaching Old Drugs New Tricks: Statins for COVID-19? (2020) (33)
- State of the art: Atherosclerosis in a limited edition (1998) (33)
- LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase. (2020) (33)
- Does nicotinic acid (niacin) lower blood pressure? (2009) (33)
- A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis[S] (2009) (33)
- Zinc transporter Slc39a8 is essential for cardiac ventricular compaction (2018) (32)
- Precision screening for familial hypercholesterolaemia: a machine learning study applied to electronic health encounter data. (2019) (32)
- Autophagy Is Required for Sortilin-Mediated Degradation of Apolipoprotein B100 (2018) (32)
- Functional validation of new pathways in lipoprotein metabolism identified by human genetics (2011) (32)
- Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians (2009) (32)
- Management of selected lipid abnormalities. Hypertriglyceridemia, low HDL cholesterol, lipoprotein(a), in thyroid and renal diseases, and post-transplantation. (2000) (32)
- Large-Scale Analysis of Determinants, Stability, and Heritability of High-Density Lipoprotein Cholesterol Efflux Capacity (2017) (32)
- HDL: structure, function and metabolism. (1991) (32)
- Lysosomal Acid Lipase Deficiency--A New Therapy for a Genetic Lipid Disease. (2015) (31)
- Drugs in development: targeting high-density lipoprotein metabolism and reverse cholesterol transport (2005) (31)
- Optical Measurement Techniques: Fundamentals and Applications (2011) (31)
- Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases (2020) (31)
- Potent peroxisome proliferator-activated receptor-α agonist treatment increases cholesterol efflux capacity in humans with the metabolic syndrome. (2015) (31)
- Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry. (2013) (30)
- Practical immunoaffinity-enrichment LC-MS for measuring protein kinetics of low-abundance proteins. (2014) (30)
- Generation of iPSCs as a Pooled Culture Using Magnetic Activated Cell Sorting of Newly Reprogrammed Cells (2015) (30)
- Stage Response Calibration of the Mark III and Marple Personal Cascade Impactors (1991) (30)
- Cholesteryl Ester Transfer Protein Inhibition With Anacetrapib Decreases Fractional Clearance Rates of High-Density Lipoprotein Apolipoprotein A-I and Plasma Cholesteryl Ester Transfer Protein (2016) (30)
- Usefulness of insulin resistance estimation and the metabolic syndrome in predicting coronary atherosclerosis in type 2 diabetes mellitus. (2011) (30)
- Prospective CYP2C19 Genotyping to Guide Antiplatelet Therapy Following Percutaneous Coronary Intervention (2020) (30)
- Inflammation induces fibrinogen nitration in experimental human endotoxemia. (2009) (30)
- CD44 Expressed on Both Bone Marrow–Derived and Non–Bone Marrow–Derived Cells Promotes Atherogenesis in ApoE-Deficient Mice (2008) (30)
- Prior Authorization Requirements for Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors Across US Private and Public Payers (2018) (29)
- Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes (2018) (29)
- A new feature on the cholesterol-lowering landscape (2001) (29)
- A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “ARE2 Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance* (2013) (29)
- Inhibition of cholesteryl ester transfer protein activity: A new therapeutic approach to raising high-density lipoprotein (2004) (29)
- ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma[S] (2012) (29)
- Role of N-linked glycosylation in the secretion and activity of endothelial lipase Published, JLR Papers in Press, September 1, 2004. DOI 10.1194/jlr.M400162-JLR200 (2004) (29)
- Recent advances in the pharmacological management of hypercholesterolaemia. (2016) (28)
- CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages—Brief Report (2017) (28)
- Measurements of thermal accommodation coefficients. (2005) (28)
- Creatine kinase, a magnetic resonance-detectable marker gene for quantification of liver-directed gene transfer. (2005) (28)
- The Effects of Apolipoprotein F Deficiency on High Density Lipoprotein Cholesterol Metabolism in Mice (2012) (28)
- Targeting ApoC-III to Reduce Coronary Disease Risk (2016) (28)
- Heterozygosity for apolipoprotein E-4Philadelphia(Glu13----Lys, Arg145----Cys) is associated with incomplete dominance of type III hyperlipoproteinemia. (1992) (28)
- Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia. (2017) (27)
- Genetic and Epigenetic Fine Mapping of Complex Trait Associated Loci in the Human Liver (2018) (27)
- A Novel APOC2 Missense Mutation Causing Apolipoprotein C-II Deficiency With Severe Triglyceridemia and Pancreatitis (2017) (27)
- Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion (2019) (27)
- Evaluation of the Pooled Cohort Equations for Prediction of Cardiovascular Risk in a Contemporary Prospective Cohort. (2017) (27)
- Calculations of the near-wall thermophoretic force in rarefied gas flow (2002) (27)
- Therapeutic Targets of Triglyceride Metabolism as Informed by Human Genetics. (2016) (27)
- Upregulation of Macrophage Endothelial Lipase by Toll-Like Receptors 4 and 3 Modulates Macrophage Interleukin-10 and -12 Production (2007) (27)
- Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure (2020) (27)
- Measurement of Gas‐Surface Accommodation (2009) (27)
- Managing diabetic dyslipidemia: Beyond statin therapy (2009) (27)
- Insulin resistance and chronic kidney disease progression, cardiovascular events, and death: findings from the chronic renal insufficiency cohort study (2019) (27)
- CD44 Regulates Vascular Gene Expression in a Proatherogenic Environment (2007) (27)
- Familial HDL deficiency due to marked hypercatabolism of normal apoA-I. (1993) (26)
- Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice (2018) (26)
- Gene therapy for atherosclerosis (1997) (26)
- Accelerating the pace of atherosclerosis research. (2015) (26)
- Apolipoprotein E and Coronary Disease: A Puzzling Paradox (2006) (26)
- Cholesteryl ester transfer protein and coronary artery disease: an observation with therapeutic implications. (2004) (26)
- Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy. (2016) (26)
- Genetics of height and risk of atrial fibrillation: A Mendelian randomization study (2019) (26)
- Reduced efficacy of rosuvastatin by St. John's Wort. (2009) (26)
- High-density lipoprotein particle number: a better measure to quantify high-density lipoprotein? (2012) (26)
- Exome-wide evaluation of rare coding variants using electronic health records identifies new gene–phenotype associations (2021) (26)
- ApoA-II kinetics in humans using endogenous labeling with stable isotopes: slower turnover of apoA-II compared with the exogenous radiotracer method. (1996) (26)
- A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation (2021) (25)
- In vivo metabolism of apolipoprotein A-IV in severe hypertriglyceridemia: a combined radiotracer and stable isotope kinetic study. (1994) (25)
- Differential network enrichment analysis reveals novel lipid pathways in chronic kidney disease (2019) (25)
- Verification studies of thermophoretic protection for extreme ultraviolet masksa) (2005) (25)
- Text mining applied to electronic cardiovascular procedure reports to identify patients with trileaflet aortic stenosis and coronary artery disease (2017) (25)
- The future of humans as model organisms (2018) (25)
- Extended-release niacin acutely suppresses postprandial triglyceridemia. (2012) (25)
- Measurement of fractional synthetic rates of multiple protein analytes by triple quadrupole mass spectrometry. (2012) (24)
- Decreased Expression of ARV1 Results in Cholesterol Retention in the Endoplasmic Reticulum and Abnormal Bile Acid Metabolism* (2010) (24)
- ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion (2017) (24)
- The heart in Tangier disease. Severe coronary atherosclerosis with near absence of high-density lipoprotein cholesterol. (1992) (24)
- Genetic susceptibility to atherosclerosis: insights from mice. (2000) (24)
- Effects of the cholesteryl ester transfer protein inhibitor, TA-8995, on cholesterol efflux capacity and high-density lipoprotein particle subclasses. (2016) (24)
- VLDL Hydrolysis by Hepatic Lipase Regulates PPARδ Transcriptional Responses (2011) (24)
- Endothelial Function and Weight Loss: Comparison of Low-Carbohydrate and Low-Fat Diets (2012) (24)
- Massively parallel simulations of Brownian dynamics particle transport in low pressure parallel‐plate reactors (1996) (24)
- Apolipoprotein A-I Infusion Therapies for Coronary Disease: Two Outs in the Ninth Inning and Swinging for the Fences. (2018) (24)
- Clinical Implications of Lipid Genetics for Cardiovascular Disease (2010) (24)
- Lipoproteins containing apolipoprotein B isolated from patients with abetalipoproteinemia and homozygous hypobetalipoproteinemia: identification and characterization. (1995) (23)
- Persistent liver expression of murine apoA-l using vectors based on adeno-associated viral vectors serotypes 5 and 1. (2006) (23)
- A method to employ the aerodynamic particle sizer factory calibration under different operating conditions (1990) (23)
- Intercellular Adhesion Molecule 1 (ICAM-1) Gene Variant Is Associated with Coronary Artery Calcification Independent of Soluble ICAM-1 Levels (2004) (23)
- N-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins Published, JLR Papers in Press, June 3, 2007. (2007) (23)
- Apolipoprotein E-mediated cell cycle arrest linked to p27 and the Cox2-dependent repression of miR221/222. (2013) (23)
- Demystifying triglycerides: a practical approach for the clinician. (2005) (23)
- Lipids, Apolipoproteins and Lipoproteins (1994) (23)
- Pathophysiology and management of low high-density lipoprotein cholesterol. (1999) (23)
- Particle transport modelling in semiconductor process environments (1994) (23)
- Genetics of increased HDL cholesterol levels: insights into the relationship between HDL metabolism and atherosclerosis. (2003) (23)
- Functional Characterization of Organoids Derived From Irreversibly Damaged Liver of Patients With NASH (2021) (23)
- Management of lipids in the prevention of cardiovascular events. (2008) (23)
- Lecithin: cholesterol acyltransferase and atherosclerosis: another high-density lipoprotein story that doesn't quite follow the script. (2009) (22)
- Rates of COVID-19–Related Outcomes in Cancer Compared With Noncancer Patients (2021) (22)
- Role of SN1 Lipases on Plasma Lipids in Metabolic Syndrome and Obesity (2014) (22)
- Polygenic Risk Scores and Coronary Artery Disease: Ready for Prime Time? (2020) (22)
- Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis. (2014) (22)
- Disrupting upstream translation in mRNAs is associated with human disease (2021) (22)
- Endocannabinoid antagonism: blocking the excess in the treatment of high-risk abdominal obesity. (2007) (22)
- PPARγ activation redirects macrophage cholesterol from fecal excretion to adipose tissue uptake in mice via SR-BI. (2011) (22)
- Gene-based interaction analysis by incorporating external linkage disequilibrium information (2011) (22)
- Association of Telomere Length With Risk of Disease and Mortality. (2022) (22)
- Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism. (2013) (21)
- New targets and emerging therapies for reducing LDL cholesterol (2007) (21)
- Cholesteryl ester transfer protein (CETP) inhibitors: is there life after torcetrapib? (2008) (21)
- Angiopoietin-like protein 4: A therapeutic target for triglycerides and coronary disease? (2018) (21)
- DSMC convergence behavior of the hard-sphere-gas thermal conductivity for Fourier heat flow. (2005) (21)
- Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis (2020) (21)
- Effects of lipoprotein apheresis on PCSK9 levels. (2015) (21)
- Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease (2021) (20)
- Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics (2018) (20)
- Boundary element method calculations of the mobility of nonspherical particles—1. Linear chains (1993) (20)
- Discovery and validation of new molecular targets in treating dyslipidemia: the role of human genetics. (2009) (20)
- Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease (2020) (20)
- Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity (2021) (20)
- Metabolism of two forms of apolipoprotein B of VLDL by rat liver. (1983) (20)
- Lipoprotein (a) level, apolipoprotein (a) size, and risk of unexplained ischemic stroke in young and middle-aged adults. (2016) (20)
- Prediabetic obese adolescents have a more atherogenic lipoprotein profile compared with normoglycemic obese peers. (2012) (20)
- A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans[S] (2017) (20)
- A tetracycline‐regulated adenoviral expression system for in vivo delivery of transgenes to lung and liver (2003) (20)
- Is the cholesteryl ester transfer protein proatherogenic or antiatherogenic in humans? (2007) (20)
- Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases: A Mendelian Randomization Study (2020) (20)
- Measurement of waist circumference predicts coronary atherosclerosis beyond plasma adipokines (2013) (20)
- Coronary Artery Calcification at Electron Beam Computed Tomography is Increased in Asymptomatic Type 2 Diabetics Independent of Traditional Risk Factors1 (2002) (20)
- Mixed modelling to characterize genotype–phenotype associations (2005) (20)
- A computational investigation of noncontinuum gas-phase heat transfer between a heated microbeam and the adjacent ambient substrate (2006) (20)
- Genetics of Smoking and Risk of Atherosclerotic Cardiovascular Diseases (2021) (20)
- N-Glycosylation Defects in Humans Lower Low-Density Lipoprotein Cholesterol Through Increased Low-Density Lipoprotein Receptor Expression (2019) (19)
- Secreted miRNAs suppress atherogenesis (2012) (19)
- Effects of coexpression of the LDL receptor and apoE on cholesterol metabolism and atherosclerosis in LDL receptor-deficient mice. (2001) (19)
- Design and synthesis of boronic acid inhibitors of endothelial lipase. (2012) (19)
- Lipoprotein (a) in patients with hyperlipidaemia (1995) (19)
- Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E[S] (2017) (19)
- A phase 2 trial of the efficacy and safety of evinacumab in patients with severe hypertriglyceridemia (2021) (19)
- Characterization of high-density apolipoprotein particles A-I and A-I:A-II isolated from humans with cholesteryl ester transfer protein deficiency. (1995) (19)
- Phenotypic correction of lipid storage and growth arrest in wolman disease fibroblasts by gene transfer of lysosomal acid lipase. (2001) (19)
- Beyond LDL cholesterol in assessing cardiovascular risk: apo B or LDL-P? (2013) (19)
- Inhibition of Angiopoietin-Like Protein 3 With Evinacumab in Subjects With High and Severe Hypertriglyceridemia. (2021) (19)
- Polyphenols and cholesterol efflux: is coffee the next red wine? (2010) (19)
- The role of resting myocardial blood flow and myocardial blood flow reserve as a predictor of major adverse cardiovascular outcomes (2020) (19)
- Mighty Minipig in Fight Against Cardiovascular Disease (2013) (19)
- patient-oriented and epidemiological research Effects of cholesteryl ester transfer protein inhibition on apolipoprotein A-II-containing HDL subspecies and apolipoprotein A-II metabolism (2009) (18)
- Impact of dietary fat type within the context of altered cholesterol homeostasis on cholesterol and lipoprotein metabolism in the F1B hamster. (2010) (18)
- Novel ENU-Induced Point Mutation in Scavenger Receptor Class B, Member 1, Results in Liver Specific Loss of SCARB1 Protein (2009) (18)
- 'Multipurpose oxidase' in atherogenesis (2007) (18)
- Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition (2021) (18)
- Genetics of Lipid Traits and Relationship to Coronary Artery Disease (2013) (18)
- Tribbles-1: a novel regulator of hepatic lipid metabolism in humans (2015) (18)
- The effects of statin therapy on plasma markers of inflammation in patients without vascular disease (2005) (18)
- Combined effects of cholesterol reduction and apolipoprotein A-I expression on atherosclerosis in LDL receptor deficient mice. (2002) (18)
- Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism Published, JLR Papers in Press, November 21, 2007. (2008) (18)
- Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism (2012) (18)
- DSMC Moving‐Boundary Algorithms for Simulating MEMS Geometries with Opening and Closing Gaps (2011) (18)
- Apolipoproteins regulate the kinetics of endothelial lipase-mediated hydrolysis of phospholipids in reconstituted high-density lipoproteins. (2004) (17)
- Comparative in vivo metabolism of apolipoproteins E2 and E4 in heterozygous apoE2/4 subjects. (2002) (17)
- A comparison of Lp(a) levels in fresh and frozen plasma using ELISAs with either anti-apo(a) or anti-apoB reporting antibodies. (1994) (17)
- Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies (2010) (17)
- Endothelial lipase is less effective at influencing HDL metabolism in vivo in mice expressing apoA-II Published, JLR Papers in Press, July 30, 2006. (2006) (17)
- Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries (2022) (17)
- Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice. (2009) (17)
- Meta-analysis fine-mapping is often miscalibrated at single-variant resolution (2022) (17)
- New insights into the role of glycosylation in lipoprotein metabolism (2017) (17)
- Angioid streaks associated with abetalipoproteinemia. (1994) (17)
- LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in obese adults with modest hypertriglyceridemia. (2021) (17)
- Reconstituted high‐density lipoprotein can elevate plasma alanine aminotransferase by transient depletion of hepatic cholesterol: role of the phospholipid component (2016) (17)
- Directional ABCA1-mediated cholesterol efflux and apoB-lipoprotein secretion in the retinal pigment epithelium (2018) (17)
- Lipoprotein(a) levels and heart transplantation atherosclerosis. (1998) (17)
- Novel In Vivo Method for Measuring Cholesterol Mass Flux in Peripheral Macrophages (2011) (16)
- Therapy to reduce risk of coronary heart disease (2003) (16)
- Spotlight on HDL biology: new insights in metabolism, function, and translation. (2014) (16)
- Mining the social mediome. (2015) (16)
- Secretory Phospholipase A2-IIA and Cardiovascular Disease A Mendelian Randomization Study (2017) (16)
- New Therapeutic Approaches for Familial Hypercholesterolemia. (2018) (16)
- The virtual cyclone : A device for nonimpact particle separation (1997) (16)
- Thyroxine binding to the apolipoproteins of high density lipoproteins HDL2 and HDL3. (1992) (16)
- Structure-function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells. (2008) (15)
- Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways. (2020) (15)
- Effects of Renal Replacement Therapy on Plasma Lipoprotein(a) Levels (2007) (15)
- Genomic Risk Stratification Predicts All-Cause Mortality After Cardiac Catheterization (2018) (15)
- Association of APOL1 Risk Alleles with Cardiovascular Disease in African Americans in the Million Veteran Program. (2019) (15)
- Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations (2019) (15)
- HDL (High-Density Lipoprotein) Subclasses, Lipid Content, and Function Trajectories Across the Menopause Transition: SWAN-HDL Study. (2020) (15)
- Abstract 16516: Sustained LDL-C Lowering and Stable Hepatic Fat Levels in Patients With Homozygous Familial Hypercholesterolemia Treated With the Microsomal Triglyceride Transfer Protein Inhibitor, Lomitapide: Results of an Ongoing Long-Term Extension Study (2013) (15)
- Short‐Term Treatment with High‐Dose Atorvastatin Reduces LDL Cholesterol but Shows no Anti‐Inflammatory Effects in Normolipidemic Subjects with Normal CRP Levels (2010) (15)
- Endothelial Lipase Activity Predicts High-Density Lipoprotein Catabolism in Hemodialysis: Novel Phospholipase Assay in Postheparin Human Plasma (2012) (15)
- Counter-current chromatography of lipoproteins with a polymer phase system using the cross-axis synchronous coil planet centrifuge. (1992) (15)
- Comparison of high-density lipoprotein cholesterol to apolipoprotein A-I and A-II to predict coronary calcium and the effect of insulin resistance. (2011) (15)
- Gain-of-function mutations and therapeutic implications: lipoprotein lipase S447X to the rescue. (2005) (14)
- On-Statin Resistin, Leptin, and Risk of Recurrent Coronary Events After Hospitalization for an Acute Coronary Syndrome (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Study). (2015) (14)
- Glomerular and Tubular Epithelial Defects in kd/kd Mice Lead to Progressive Renal Failure (2005) (14)
- COVID-19 associated risks of myocardial infarction in persons with familial hypercholesterolemia with or without ASCVD (2021) (14)
- A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease (2019) (14)
- Germline Mutations in CIDEB and Protection against Liver Disease. (2022) (14)
- Dyslipidemia in insulin resistance: clinical challenges and adipocentric therapeutic frontiers (2008) (14)
- A common biological basis of obesity and nicotine addiction (2019) (14)
- Cholesterol efflux capacity of high-density lipoprotein correlates with survival and allograft vasculopathy in cardiac transplant recipients. (2016) (14)
- Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals (2020) (14)
- Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterol. (2016) (14)
- Glycosylation of endothelial lipase at asparagine-116 reduces activity and the hydrolysis of native lipoproteins in vitro and in vivo Published, JLR Papers in Press, February 24, 2007. (2007) (14)
- Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation (2011) (13)
- Could Exercise Metabolomics Pave the Way for Gymnomimetics? (2010) (13)
- Apolipoprotein A-I and cholesterol efflux: the good, the bad, and the modified. (2014) (13)
- Human knockouts in a cohort with a high rate of consanguinity (2015) (13)
- Tangier disease: isolation and characterization of LpA-I, LpA-II, LpA-I: A-II and LpA-IV particles from plasma. (1993) (13)
- Noninvasive procedures for subclinical atherosclerosis risk assessment. (1999) (13)
- Molecular Link Between Bile Acid and Lipid and Glucose Metabolism (2005) (13)
- Accuracy and Convergence of a New DSMC Algorithm. (2008) (13)
- Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease. (2011) (13)
- Structural basis of endothelial lipase tropism for HDL (2004) (13)
- Unbiased Analysis of Temporal Changes in Immune Serum Markers in Acute COVID-19 Infection With Emphasis on Organ Failure, Anti-Viral Treatment, and Demographic Characteristics (2021) (13)
- Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations. (2016) (13)
- Effect of rosiglitazone on HDL metabolism in subjects with metabolic syndrome and low HDL (2011) (13)
- Higher order lipase gene association with plasma triglycerides Published, JLR Papers in Press, June 16, 2005. DOI 10.1194/jlr.M500042-JLR200 (2005) (13)
- Showerhead-Enhanced Inertial Particle Deposition in Parallel-Plate Reactors (1998) (13)
- Human serum preβ1-high density lipoprotein levels are independently and negatively associated with coronary artery diseases (2016) (13)
- C‐Reactive Protein Modifies the Association of Plasma Leptin With Coronary Calcium in Asymptomatic Overweight Individuals (2012) (13)
- Genome-wide approaches to finding novel genes for lipid traits: the start of a long road. (2008) (12)
- Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport[S] (2017) (12)
- Inhibition of Endothelial Lipase Activity by Sphingomyelin in the Lipoproteins (2014) (12)
- Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids. (2021) (12)
- Verification studies of thermophoretic protection for EUV masks (2002) (12)
- Serum lipid expression correlates with function and regeneration following living donor liver transplantation (2016) (12)
- Genetics of Postlingual Sensorineural Hearing Loss (2020) (12)
- Monogenic causes of elevated HDL cholesterol and implications for development of new therapeutics (2013) (12)
- Impaired cholesterol efflux capacity and vasculoprotective function of high-density lipoprotein in heart transplant recipients. (2014) (12)
- Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution. (2016) (12)
- HDL as a treatment target. (2010) (12)
- Abnormal in vivo metabolism of apoB-containing lipoproteins in human apoE deficiency Published, JLR Papers in Press, April 21, 2004. DOI 10.1194/jlr.M400020-JLR200 (2004) (12)
- Boundary element method calculations of the mobility of nonspherical particles—II. Branched chains and flakes (1996) (12)
- Deletion of murine Arv1 results in a lean phenotype with increased energy expenditure (2015) (12)
- Circulating and Tissue Matricellular RNA and Protein Expression in Calcific Aortic Valve Disease. (2020) (11)
- Reporting Sex and Sex Differences in Preclinical Studies. (2018) (11)
- Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease (2021) (11)
- Sero-monitoring of health care workers reveals complex relationships between common coronavirus antibodies and SARS-CoV-2 severity (2021) (11)
- Health care worker seromonitoring reveals complex relationships between common coronavirus antibodies and COVID-19 symptom duration (2021) (11)
- Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease. (2020) (11)
- Perspective: cardiovascular disease in the postgenomic era--lessons learned and challenges ahead. (2002) (11)
- A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production. (2014) (11)
- DSMC Convergence Behavior for Fourier Flow (2005) (11)
- Gene therapy for lipoprotein disorders (2005) (11)
- Heterozygous ABCG5 Gene Deficiency and Risk of Coronary Artery Disease (2020) (11)
- High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease (2022) (11)
- Discovery of 318 novel loci for type-2 diabetes and related micro- and macrovascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis (2019) (11)
- In vivo protein metabolism utilizing stable isotopes and mass spectrometry: a new approach to the study of mutant proteins in humans. (1990) (11)
- Human genetics of atherothrombotic disease and its risk factors. (2015) (11)
- SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations (2021) (11)
- A catalog of associations between rare coding variants and COVID-19 outcomes (2020) (10)
- Candidate Gene Association Resource (CARe)Clinical Perspective (2010) (10)
- Guggulipid for the Treatment of Hypercholesterolemia (2017) (10)
- ANGPTL 3 De fi ciency and Protection Against Coronary Artery Disease (2017) (10)
- A genome-first approach to mortality and metabolic phenotypes in MTARC1 p.Ala165Thr (rs2642438) heterozygotes and homozygotes. (2021) (10)
- Val 64 Ile Polymorphism in the C-C Chemokine Receptor 2 Is Associated With Reduced Coronary Artery Calcification (2002) (10)
- Gene therapy for lipid disorders (2000) (10)
- Dyslipidaemia: Cardiovascular prevention—end of the road for niacin? (2014) (10)
- ATP binding cassette family A protein 1 determines hexosylceramide and sphingomyelin levels in human and mouse plasma[S] (2018) (10)
- Genetic regulation of OAS1 nonsense-mediated decay underlies association with risk of severe COVID-19 (2021) (10)
- Development of an unattended ground sensor for ultraviolet laser-induced fluorescence detection of biological agent aerosols (1999) (10)
- New Therapies for Coronary Artery Disease: Genetics Provides a Blueprint (2014) (10)
- Statins and cerebrovascular disease: plaque attack to prevent brain attack (1999) (10)
- Measurements of Thermal Accomodation Coefficients (2005) (10)
- ILRUN, a Human Plasma Lipid GWAS Locus, Regulates Lipoprotein Metabolism in Mice (2020) (9)
- Gene therapy for familial hypercholesterolemia. (2001) (9)
- “Pheno”menal value for human health (2016) (9)
- A unified framework identifies novel links between plasma lipids and diseases from electronic medical records across large-scale cohorts (2021) (9)
- Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program (2020) (9)
- Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes (2021) (9)
- A null mutation in ANGPTL8 does not associate with either plasma glucose or type 2 diabetes in humans (2016) (9)
- Association of Inherited Mutations in DNA Repair Genes with Localized Prostate Cancer (2021) (9)
- Expression of Type IIA Secretory Phospholipase A2 Inhibits Cholesteryl Ester Transfer Protein Activity in Transgenic Mice (2013) (9)
- Abstract 19030: Apolipoprotein C-III is Significantly Reduced by Prescription Omega-3 Free Fatty Acids (Epanova) in Patients with Severe Hypertriglyceridemia and Changes Correlate with Increases in LDL-C: A Sub-analysis of the EVOLVE trial (2012) (9)
- Perspective: Cardiovascular Disease in the Postgenomic Era-Lessons Learned and Challenges Ahead. (2002) (9)
- Genetics of lipid traits: Genome-wide approaches yield new biology and clues to causality in coronary artery disease. (2014) (9)
- Anti‐Inflammatory HDL Function, Incident Cardiovascular Events, and Mortality: A Secondary Analysis of the JUPITER Randomized Clinical Trial (2020) (9)
- Changes in cholesterol homeostasis modify the response of F1B hamsters to dietary very long chain n-3 and n-6 polyunsaturated fatty acids (2011) (9)
- SAFETY AND EFFICACY OF LY3015014, A NEW MONOCLONAL ANTIBODY TO PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) WITH AN INHERENTLY LONGER DURATION OF ACTION, IN PATIENTS WITH PRIMARY HYPERCHOLESTEROLEMIA: A RANDOMIZED, PLACEBO-CONTROLLED, DOSE-RANGING, PHASE 2 STUDY (2015) (9)
- Mendelian Randomization Analysis of Hemostatic Factors and Their Contribution to Peripheral Artery Disease—Brief Report (2020) (9)
- Lipidomic Analyses of Female Mice Lacking Hepatic Lipase and Endothelial Lipase Indicate Selective Modulation of Plasma Lipid Species (2014) (8)
- A coding variant in SR-BI (I179N) significantly increases atherosclerosis in mice (2013) (8)
- Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin (2018) (8)
- Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council". (2018) (8)
- Calculation of particle concentration around aircraft-like geometries (1993) (8)
- When HDL gets fat... (2008) (8)
- Nuclear receptors and microRNA-144 coordinately regulate cholesterol efflux. (2013) (8)
- Effects of Genetic Variants Associated with Familial Hypercholesterolemia on Low-Density Lipoprotein-Cholesterol Levels and Cardiovascular Outcomes in the Million Veteran Program (2018) (8)
- Genetically Determined Birthweight Associates With Atrial Fibrillation (2020) (8)
- A randomized controlled trial of genetic testing and cascade screening in familial hypercholesterolemia (2021) (8)
- Genetic coding variants in the niacin receptor, hydroxyl–carboxylic acid receptor 2, and response to niacin therapy (2017) (8)
- Iron-Chelating Therapy for Transfusional Iron Overload (2011) (8)
- Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes (2020) (8)
- Management of lipid disorders. (1999) (8)
- Annual Report on Sex in Preclinical Studies: Arteriosclerosis, Thrombosis, and Vascular Biology Publications in 2018. (2020) (8)
- Manganese homeostasis: from rare single-gene disorders to complex phenotypes and diseases. (2019) (8)
- Association of serum androgens and coronary artery calcium scores in women. (2019) (8)
- Particle Deposition in Parallel-Plate Reactors: Simultaneous Diffusion and External Forces (2002) (8)
- Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry (2020) (8)
- Paradoxical coronary artery disease in humans with hyperalphalipoproteinemia is associated with distinct differences in the high-density lipoprotein phosphosphingolipidome. (2017) (8)
- A large-scale multi-ethnic genome-wide association study of coronary artery disease (2021) (7)
- Lymphatics as a new active player in reverse cholesterol transport. (2013) (7)
- Microscale Rarefied Gas Dynamics and Surface Interactions for EUVL and MEMS Applications (2004) (7)
- Common genetic variants identify targets for COVID-19 and individuals at 1 high risk of severe disease 2 (2021) (7)
- TANDEM DIFFERENTIAL MOBILITY ANALYZER. (1986) (7)
- Gene therapy for dyslipidemia: Clinical prospects (1999) (7)
- Lipids and cardiovascular disease 2 HDL and cardiovascular disease (2014) (7)
- Endothelial lipase mediates efficient lipolysis of triglyceride-rich lipoproteins (2021) (7)
- Phospholipidation of HDL--how much is too much? (2011) (7)
- Cyclooxygenase-2-derived prostacyclin confers atheroprotection on female mice (2005) (7)
- Abstract 1496: Oral Administration of the Apolipoprotein A-I Mimetic Peptide D-4F in Humans with CHD Improves HDL Anti-Inflammatory Function After a Single Dose (2006) (7)
- Experimental Measurements of Thermal Accommodation Coefficients for Microscale Gas-Phase Heat Transfer. (2007) (7)
- Whole genome sequence analysis of blood lipid levels in >66,000 individuals (2021) (7)
- Tissue-specific expression pattern of human endothelial lipase in transgenic mice. (2005) (7)
- The Role of High Density Lipoproteins in Thrombosis (2002) (7)
- Vitamin E dose-response studies in humans with use of deuterated RRR-a-tocopherol 1 – 3 (7)
- Rates of COVID-19-related Outcomes in Cancer compared to non-Cancer Patients (2020) (7)
- The editor's roundtable: high-density lipoprotein cholesterol. (2007) (6)
- Current drug options for raising HDL cholesterol (2005) (6)
- JCL roundtable: drug treatment of severe forms of familial hypercholesterolemia. (2014) (6)
- A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids (2021) (6)
- Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease (2019) (6)
- Future outlook: changing perspectives on best practice. (2002) (6)
- Berman's simulation analysis and modeling. (1991) (6)
- Long-Term Efficacy and Safety of Lomitapide for the Treatment of Homozygous Familial Hypercholesterolemia: Results of the Phase 3 Extension Trial † (2015) (6)
- Self‐Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene (2020) (6)
- Abstract 439: Niacin Does Not Accelerate Reverse Cholesterol Transport in Man (2013) (6)
- Lipoproteins and the endothelium: insights from clinical research. (2000) (6)
- Research on COVID-19 through patient-reported data: a survey for observational studies in the COVID-19 pandemic (2020) (6)
- DSMC Simulations of Fourier and Couette Flow: Chapman‐Enskog Behavior and Departures Therefrom (2005) (6)
- Quantification of abdominal fat from computed tomography using deep learning and its association with electronic health records in an academic biobank (2020) (6)
- Management of selected lipid abnormalities: hypertriglyceridemia, isolated low HDL-cholesterol, lipoprotein(a), and lipid abnormalities in renal diseases and following solid organ transplantation. (2003) (6)
- Deep Apolipoprotein Proteomics to Uncover Mechanisms of Coronary Disease Risk. (2017) (6)
- Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
- Novel approaches to the treatment of dyslipidemia. (2005) (6)
- Abstract 12252: Effects of the Cholesteryl Ester Transfer Protein Inhibitor, Evacetrapib, Administered as Monotherapy or in Combination With Statins on Cholesterol Efflux and HDL Particles in Patients With Dyslipidemia (2014) (6)
- 393 A trial to determine the effect of psoriasis treatment (adalimumab, phototherapy, and placebo) on cardiometabolic disease: The vascular inflammation in psoriasis (VIP) trial (2018) (5)
- Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders (2022) (5)
- Experimental Therapeutics for Challenging Clinical Care of a Patient with an Extremely Rare Homozygous APOC2 Mutation (2020) (5)
- Trends and Factors Associated With Insurer Approval of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor Prescriptions. (2020) (5)
- Association of the Vitamin D Metabolism Gene CYP 24 A 1 With Coronary Artery Calcification (2010) (5)
- Abstract 1077: A Phase III Study of Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide (AEGR-733) in Patients With Homozygous Familial Hypercholesterolemia: Interim Results at 6 Months (2009) (5)
- Lipid-lowering treatment for homozygous familial hypercholesterolaemia – Authors' reply (2013) (5)
- MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data (2021) (5)
- The relationship between lipoproteins and insulin sensitivity in youth with obesity and abnormal glucose tolerance. (2022) (5)
- Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease (2021) (5)
- Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program (2020) (5)
- DSMC Convergence Behavior for Transient Flows. (2007) (5)
- Endothelial plasticity drives aberrant vascularization and impedes cardiac repair after myocardial infarction (2022) (5)
- Dynamic Changes in Central and Peripheral Neuro-Injury vs. Neuroprotective Serum Markers in COVID-19 Are Modulated by Different Types of Anti-Viral Treatments but Do Not Affect the Incidence of Late and Early Strokes (2021) (5)
- Polygenic Risk Scores in Familial Hypercholesterolemia. (2019) (5)
- Abstract 71: Assessment of Reverse Cholesterol Transport in Vivo in Humans: A Novel Method (2012) (5)
- Abstract 12169: LDL-C Levels and Treatment Patterns Among Adults With Heterozygous Familial Hypercholesterolemia in the United States: Data From the CASCADE-FH Registry (2015) (5)
- Multiplexed Targeted Resequencing Identifies Coding and Regulatory Variation Underlying Phenotypic Extremes of High-Density Lipoprotein Cholesterol in Humans (2018) (5)
- S 447 X variant of the lipoprotein lipase gene , lipids , and risk of coronary heart disease in 3 prospective cohort studies (2009) (5)
- PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort (2020) (5)
- Limited-Variant Screening vs Comprehensive Genetic Testing for Familial Hypercholesterolemia Diagnosis. (2021) (5)
- TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes. (2021) (5)
- Measuring niacin-associated skin toxicity (NASTy) stigmata along with symptoms to aid development of niacin mimetics[S] (2017) (5)
- Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors (2022) (5)
- Macular Degeneration and CETP Inhibition. (2022) (5)
- HeterozygousABCG5Gene Deficiency and Risk of Coronary Artery Disease (2020) (5)
- Decrease in Angiotensin-Converting Enzyme activity but not concentration in plasma/lungs in COVID-19 patients offers clues for diagnosis/treatment (2022) (5)
- Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes (2022) (4)
- The Role of HDL-C in the Management of Atherosclerosis (2015) (4)
- Genomic medicine in the prevention and treatment of atherosclerotic cardiovascular disease. (2012) (4)
- Adjustment of nonconfounding covariates in case-control genetic association studies (2018) (4)
- A regression framework to uncover pleiotropy in large-scale electronic health record data (2019) (4)
- Slaying the metabolic syndrome. Are we battling the Hydra or the Chimera? (2004) (4)
- Calibration of the Phase Doppler Particle Analyzer with Monodisperse Droplets (1993) (4)
- FBN1 Coding Variants and Nonsyndromic Aortic Disease. (2019) (4)
- Development and optimization of a cryogenic-aerosol-based wafer-cleaning system (1998) (4)
- Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure (2022) (4)
- EDEM3 Modulates Plasma Triglyceride Level through Its Regulation of LRP1 Expression (2019) (4)
- RNA-binding protein A1CF modulates plasma triglyceride levels through posttranscriptional regulation of stress-induced VLDL secretion (2018) (4)
- Abstract: 103 EFFECTS OF LOW DOSE MTP INHIBITION ALONE AND IN COMBINATION WITH OTHER LIPID-LOWERING DRUGS ON HEPATIC FAT AND PLASMA LIPIDS (2009) (4)
- Opposing effects of ABCG5/8 function on myocardial infarction and gallstone disease. (2014) (4)
- The anticyclone: A device for nonimpact particle separation (1996) (4)
- Abstract 17396: Apheresis Treatment does not Affect the Lipid-Lowering Efficacy of Lomitapide, a Microsomal Triglyceride Transfer Protein Inhibitor, in Patients with Homozygous Familial Hypercholesterolemia (2012) (4)
- An Improved‐Accuracy DSMC Algorithm (2009) (4)
- Efficacy of rosuvastatin 10 mg in patients with the metabolic syndrome. Discussions (2003) (4)
- Abstract 1274: Serum Cholesterol Efflux Capacity, a Measure of HDL-C Quality, Varies According to Coronary Artery Disease Status Independently of HDL-C Quantity (2009) (4)
- DSMC SIMULATIONS OF THE THERMOPHORETIC FORCE ON SPHERICAL PARTICLES IN A POLYATOMIC GAS (2003) (4)
- A systematic review of the natural history and biomarkers of primary lecithin:cholesterol acyltransferase deficiency (2022) (4)
- MANAGEMENT OF SELECTED LIPID ABNORMALITIES (2001) (4)
- Boundary element method calculations of the mobility of nonspherical particles-3. Parallel implementation for long chains (1999) (4)
- Clinical utility of coronary calcification scanning in primary prevention (1999) (4)
- Cell lipid metabolism modulators 2-bromopalmitate, D609, monensin, U18666A and probucol shift discoidal HDL formation to the smaller-sized particles: implications for the mechanism of HDL assembly. (2016) (4)
- Rare genetic variants explain missing heritability in smoking (2022) (4)
- Bi-allelic variants in the ER quality control mannosidase gene EDEM3 cause a congenital disorder of glycosylation. (2021) (4)
- Abstract 17086: Alirocumab LDL-C-Lowering Efficacy in Patients With Moderate CKD (2015) (4)
- Impact of high doses of the MTP-Inhibitor, AEGR-733, on the single dose Pharmacokinetics of Atorvastatin and Rosuvastatin (2007) (4)
- Gene therapy for genetic lipid disorders: lipoprotein lipase deficiency as a paradigm. (2005) (4)
- Particle-contamination analysis for reticles in carrier inner pods (2008) (4)
- Nanoparticle Knudsen layers in gas-filled microscale geometries. (2008) (4)
- Dyslipidemia (2020) (4)
- INITIAL RESULTS FROM THE CASCADE-FH REGISTRY: CASCADE SCREENING FOR AWARENESS AND DETECTION OF FAMILIAL HYPERCHOLESTEROLEMIA (2015) (4)
- Changes in lipoprotein(a) concentration after orthotopic heart transplantation. (2000) (4)
- Lipid droplet screen in human hepatocytes identifies TRRAP as a regulator of cellular triglyceride metabolism (2021) (4)
- Genome-first approach to rare EYA4 variants and cardio-auditory phenotypes in adults (2021) (4)
- Statin therapy in heart failure: is it time for a second look? (2014) (3)
- Abstract 823: Inhibition of Cholesterol Absorption with Ezetimibe Promotes Macrophage to Feces Reverse Cholesterol Transport in Mice (2007) (3)
- N-Glycosylation Defects in Man Lower LDL-Cholesterol Through Increased LDL Receptor Expression. (2019) (3)
- Pediatric Familial Hypercholesterolemia: Children and Adolescents Enrolled in the CAscade SCreening for Awareness (2017) (3)
- Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection (2022) (3)
- Comorbidities in lichen planus by phenome‐wide association study in two biobank population cohorts * (2022) (3)
- The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population (2022) (3)
- Vasomotor symptoms and lipids/lipoprotein subclass metrics in midlife women: Does level of endogenous estradiol matter? The SWAN HDL Ancillary Study. (2020) (3)
- Specificity of ABCA7-mediated cell lipid efflux. (2022) (3)
- Measurement of Atherogenic Lipoproteins in Cardiovascular Risk Assessment (2006) (3)
- Knockout of Adamts7, A Novel CAD Locus in Humans, Reduces Atherosclerosis in Mice (2015) (3)
- Guidance for the diagnosis and treatment of hypolipidemia disorders. (2022) (3)
- Abstract: P471 IMPACT OF THE MTP-INHIBITOR AEGR-733 ON THE SINGLE-DOSE PHARMACOKINETICS OF EXTENDED-RELEASE NIACIN (2009) (3)
- Noncontinuum Gas-Phase Heat Transfer From a Heated Microbeam to the Adjacent Substrate (2005) (3)
- DSMC simulations of the thermophoretic force on a spherical macroscopic particle (2001) (3)
- Familial Chylomicronemia Syndrome With a Novel Homozygous LPL Mutation Identified in Three Siblings in Their 50s (2019) (3)
- Acute inflammation increases the selective uptake of HDL-cholesteryl esters into adrenals of mice overexpressing human secretory phospholipase A 2 (2003) (3)
- Sortilin restricts secretion of apolipoprotein B-100 by hepatocytes under stressed but not basal conditions (2022) (3)
- Particle Transport in Parallel-Plate Reactors (1999) (3)
- Multi-ethnic genome-wide association study for atrial fibrillation (2018) (3)
- The disappearing high density lipoprotein syndrome. (2015) (3)
- Abstract 3698: Impact of the MTP-Inhibitor, AEGR-733, as Monotherapy and in Combination with Ezetimibe on Lipid Subfractions as Measured by NMR Spectroscopy (2008) (3)
- Polygenic Risk Scores for Cardio-renal-metabolic Diseases in the Penn Medicine Biobank (2019) (3)
- Abstract 993: AAV8-mediated Overexpression of Lecithin-cholesterol Acyltransferase Fails to Promote Macrophage Reverse Cholesterol Transport in Vivo (2007) (3)
- Improving cardiovascular outcomes by intensifying low density lipoprotein lowering therapy in high-risk patients. (2016) (3)
- Genetic Disorders of Lipoprotein Metabolism (2007) (3)
- Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques. (2011) (3)
- APOLIPOPROTEIN(A) DEPOSITION IN ATHEROSCLEROTIC PLAQUES OF CEREBRAL VESSELS AND ARTERIOLOSCLEROTIC PARENCHYMAL VESSELS (1996) (3)
- Correlates and Predictors of Cerebrospinal Fluid Cholesterol Efflux Capacity from Neural Cells, a Family of Biomarkers for Cholesterol Epidemiology in Alzheimer's Disease. (2020) (3)
- Recent advances in lipoprotein metabolism and the genetic dyslipoproteinemias. (1991) (3)
- Associations of endogenous hormones with HDL novel metrics across the menopause transition: The SWAN HDL Study. (2021) (3)
- The role of lipoprotein subfractions in coronary artery disease: A Mendelian randomization study (2019) (3)
- Abstract 19753: Hdl Cholesterol Efflux Capacity is Inversely Associated With Incident Chd Events Independent of Hdl-c and Apoa-i Concentrations (2014) (3)
- Longitudinal urinary biomarkers of immunological activation in covid-19 patients without clinically apparent kidney disease versus acute and chronic failure (2021) (3)
- Mediterranean Approach to Improving High-Density Lipoprotein Function (2017) (3)
- Using DSMC to Compute the Force on a Particle in a Rarefied Gas Flow (2003) (3)
- Development and feasibility of quantitative dynamic cardiac imaging for mice using μSPECT (2020) (3)
- Practical application of in situ aerosol measurement (1993) (3)
- Abstract 1695: The Cholesterol Efflux Capacity of Serum Predicts Carotid Intimal-Medial Thickness Independently of HDL-C and Apo A-I Levels (2008) (3)
- Disentangling the Causal Association of Plasma Lipid Traits and Type 2 Diabetes Using Human Genetics. (2016) (3)
- Antisense oligonucleotides for atherosclerotic disease (2020) (3)
- Psoriasis is associated with decreased adiponectin levels beyond cardiovascular and metabolic risk factors (2012) (3)
- JCL Roundtable: diagnosis of severe familial hypercholesterolemia. (2013) (3)
- Analytical and numerical normal solutions of the Boltzmann equation for highly nonequilibrium fourier and couette flows. (2006) (3)
- High-density lipoprotein: NO failure in heart failure. (2013) (3)
- Impact of the MTP Inhibitor AEGR-733 on Pharmacokinetics of Statins (2007) (3)
- Transport and Deposition of Aerosol Particles (2018) (3)
- Abstract 13290: Minor Impact of Chromosome 9p21.3 Genetic Variation on Atherosclerosis Burden in Patients with Established Coronary Artery Disease (2010) (2)
- Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver (2021) (2)
- Associations of HDL metrics with coronary artery calcium score and density among women traversing menopause (2021) (2)
- A Genome-First Approach to Rare Variants in Dominant Postlingual Hearing Loss Genes in a Large Adult Population (2021) (2)
- Abstract 1319: Plasma Levels of Fatty Acid Binding Proteins 4 and 5 are Markers of Adiposity and the Metabolic Syndrome but are not Independent Predictors of Subclinical Atherosclerosis in Type 2 Diabetes (2007) (2)
- Efficacy and safety of the PCSK9 inhibitor alirocumab 300 mg every 4 weeks in patients with ASCVD. (2017) (2)
- Abstract 18721: Diacylglycerol Kinase ? (DGKB) Genotype Predicts Response to Niacin Induced Flushing and Changes in Insulin in the Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes (AIM-HIGH) Trial (2013) (2)
- Atherosclerosis, acute coronary events, and cholesterol-lowering: a new paradigm. (1998) (2)
- Aerosol production by high-velocity molten-metal droplets (1988) (2)
- Abstract 17380: Genetic Variation in PCSK9 and Protection From Peripheral Artery Disease (2017) (2)
- SAI-25: Interaction of the paraoxonase genes pon1 and pon2 and the methylenetetrahydrofolate reductase gene and association with coronary artery calcification using electron-beam computed tomography (2001) (2)
- VLDL ApoB-100 and ApoE Metabolism in Male and Female Subjects Utilizing the Stable Isotope Technique (1993) (2)
- Protection of extreme ultraviolet lithography masks. I. Thermophoretic protection factors at low pressure for diffusing nanoscale particles (2015) (2)
- Heterozygous ATP-binding Cassette Transporter G5 Gene Deficiency and Risk of Coronary Artery Disease (2019) (2)
- Lipids and Atherosclerosis Annual 2003 (2003) (2)
- Dietary Vitamin E Intake Is Associated With a Reduced Risk of Developing Digestive Diseases and Nonalcoholic Fatty Liver Disease (2022) (2)
- Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation (2017) (2)
- Contemporary Reviews in Cardiovascular Medicine Cholesterol Efflux and Atheroprotection Advancing the Concept of Reverse Cholesterol Transport (2012) (2)
- NASH patient liver derived organoids exhibit patient specific NASH phenotypes and drug responses (2019) (2)
- Genomics and phenomics of body mass index reveals a complex disease network (2022) (2)
- Guggulipid and Cholesterol Levels (2003) (2)
- Linking abdominal imaging traits to electronic health record phenotypes (2020) (2)
- Genome-wide association study of peripheral artery disease in the Million Veteran Program (2019) (2)
- Soluble FMS-Like Tyrosine Kinase-1 Is a Circulating Biomarker Associated With Calcific Aortic Stenosis. (2019) (2)
- Intracoronary Imaging, Reverse Cholesterol Transport, and Transcriptomics: Precision Medicine in CAD? (2017) (2)
- High-density lipoprotein cholesterol therapies: the next frontier in lipid management. (2006) (2)
- SARS-CoV-2 seropositivity and seroconversion in patients undergoing active cancer-directed therapy (2021) (2)
- The relationship between autism spectrum and sleep–wake traits (2021) (2)
- Renin-Angiotensin System and Atherothrombotic Disease (2017) (2)
- Atherogenic Lipid Metabolism in Obesity (2011) (2)
- Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoproteins (2018) (2)
- A pilot trial to examine the effect of high-dose niacin on arterial wall inflammation using fluorodeoxyglucose positron emission tomography. (2015) (2)
- EFFECT OF CONTINUOUS-POSITIVE AIRWAY PRESSURE, WEIGHT LOSS OR BOTH ON LARGE ARTERY STIFFNESS IN SUBJECTS WITH OBSTRUCTS SLEEP APNEA (2013) (2)
- Particle transport in plasma reactors (1995) (2)
- ATVB In Focus (2005) (2)
- Lipoprotein(a): a molecular vignette of an evolving risk factor (2000) (2)
- Associations between cardiovascular disease, cancer and very low HDL cholesterol in the REasons for Geographical And Racial Differences in Stroke (REGARDS) study. (2017) (2)
- Efficacy and Safety of Alirocumab 300 mg Every 4 Weeks in Individuals With Type 2 Diabetes on Maximally Tolerated Statin (2019) (2)
- Disrupting upstream translation in mRNAs leads to loss-of-function associated with human disease (2020) (2)
- Protective effects of HDL-C and need to raise low levels explored. (2002) (2)
- Association Genetics and Cardiovascular Disease : A Policy Statement From the American Heart (2012) (2)
- Early prediction of decompensation (EPOD) score: Non‐invasive determination of cirrhosis decompensation risk (2022) (2)
- A genome-first approach to rare variants in hypertrophic cardiomyopathy genes MYBPC3 and MYH7 in a medical biobank (2021) (2)
- Abstract 2077: A Novel GWAS Atherosclerosis Locus Regulates Plasma Levels of CXCL12 (2009) (2)
- Apolipoprotein M Improves Survival in Congestive Heart Failure via Enhanced Akt Signaling (2016) (2)
- What is the future of lipidology (2006) (2)
- Heritability of quantitative autism spectrum traits in adults: A family‐based study (2021) (2)
- ASSOCIATION OF GENOME WIDE LOCI FOR CAD WITH DISTRIBUTION OF CORONARY DISEASE (2010) (2)
- Exome-by-phenome-wide rare variant gene burden association with electronic health record phenotypes (2019) (1)
- Genetic Variation in Blood Pressure and Lifetime Risk of Peripheral Artery Disease: A Mendelian Randomization Study (2020) (1)
- TTC39B deficiency promotes HDL production and impairs non-hdl absorption in small intestine (2014) (1)
- Abstract 118: The Effect of CETP Inhibition With Anacetrapib on the Metabolism of PCSK9 (2013) (1)
- An Experimental Investigation of the Flow in a Virtual Cyclone (1998) (1)
- Abstract 58: Adipose-Specific Deletion of ARV1 Results in Decreased HDL Cholesterol, Reduced White Adipose Tissue Mass and Improved Glucose Tolerance in Mice (2012) (1)
- Chapter 23 – Lipoprotein Disorders (2010) (1)
- Cholesteryl ester transfer protein (CETP) Inhibition as a therapeutic strategy for raising HDL-cholesterol levels and reducing atherosclerosis (2003) (1)
- Aerosol Dynamics Laboratory (1990) (1)
- FP526VASCULAR CXCR4 LIMITS ATHEROSCLEROSIS BY MAINTAINING ARTERIAL INTEGRITY (2018) (1)
- Droplet sizing calibration of the Phase Doppler Particle Analyzer (1989) (1)
- Genome-wide Association Study of Alcohol Consumption and Use Disorder in Multiple Populations (N = 274,424) (2019) (1)
- ANGPTL3 De fi ciency and Protection Against Coronary Artery Disease (1)
- Polygenic risk of psychiatric disorders exhibits cross-trait associations in electronic health record data (2019) (1)
- the Risk of Myocardial Infarction A Common Variant on Chromosome 9 p 21 Affects (2008) (1)
- DIAGNOSIS OF FAMILIAL HYPERCHOLESTEROLEMIA: A WORK IN PROGRESS (2023) (1)
- SLCO1B1 and Statin Therapy. (2018) (1)
- Th-P16:322 Microsomial transfer protein (MTP) inhibition substantially reduces cholesterol in patients with homozygous familial hypercholesterolemia (2006) (1)
- orthotopic heart transplantation (2000) (1)
- ApoC-III helical structure determines its ability to bind plasma lipoproteins and inhibit Lipoprotein Lipase-mediated triglyceride lipolysis (2020) (1)
- Vascular Protection of ACE Inhibitors—Reply (2003) (1)
- CHOLESTEROL EFFLUX CAPACITY (CEC) IN PLASMA AND CEREBROSPINAL FLUID (CSF) OF PATIENTS WITH ALZHEIMER’S DISEASE (AD) AND MILD COGNITIVE IMPAIRMENT (MCI) AND COMPARISON SUBJECTS: EFFECTS OF GENDER AND DIAGNOSIS (2018) (1)
- Unmet Needs in Understanding Lipoprotein(a) Pathophysiology: NHLBI Working Group Recommendations to Reduce Risk of Cardiovascular Disease and Aortic Stenosis (2018) (1)
- Abstract 187: Changes in High-Density Lipoprotein Cholesterol and Complement C3 are Strongly Inversely Correlated in the Setting of Niacin Therapy in Humans (2007) (1)
- P14 MYELOID TRIB1 PROMOTES EXPERIMENTAL ATHEROSCLEROSIS (2018) (1)
- Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program (2023) (1)
- Potent and Selective PPAR-Agonist LY 518674 Upregulates Both ApoA-I Production and Catabolism in Human Subjects With the Metabolic Syndrome (2008) (1)
- Genetic architecture of smoking: Evaluating rare variant contribution from deep whole-genome sequencing of up to 26,000 individuals (2021) (1)
- Abstract 502: CSL112, a Novel Formulation of Human ApoA-I, Enhances the Capacity of Serum to Efflux Cholesterol from Macrophages (2012) (1)
- DSMC Simulations of Brownian Dynamics of Particles (2002) (1)
- Fluorescent green plaques: light at the end of the catheter? (2011) (1)
- Phase Doppler droplet sizing: Scattering angle effects (1990) (1)
- The complexity of ABO in coronary heart disease – Authors' reply (2011) (1)
- Exome-wide association analysis of CT imaging-derived hepatic fat in a medical biobank (2022) (1)
- Abstract 14351: Increased Levels of IgM Autoantibodies to Oxidation-Specific Epitopes are Inversely Associated With Coronary Heart Disease: Analyses of Data From 204,257 Participants (2015) (1)
- Bioaerosol collection and concentration for microseparations-based detectors. (2005) (1)
- Chapter 2 – Transport and Deposition of Aerosol Particles (2008) (1)
- Assessing HDL Metabolism in Subjects with Elevated Levels of HDL Cholesterol and Coronary Artery Disease (2021) (1)
- A New DSMC Algorithm for Simulating Non-Continuum Gas Flows. (2008) (1)
- Modeling Microscale Heat Transfer Using Calore (2005) (1)
- Implementation of a Machine-Learning Algorithm in the Electronic Health Record for Targeted Screening for Familial Hypercholesterolemia (2021) (1)
- Guggulipid and cholesterol levels. Authors' reply (2003) (1)
- Thermal Accommodation Coefficients Based on Heat-Flux Measurements (2006) (1)
- Endothelial Lipase: A Novel Drug Target for HDL and Atherosclerosis? (2005) (1)
- Abstract 19888: Improved Longitudinal Low Density Lipoprotein Cholesterol Goal Achievement Among Familial Hypercholesterolemia Patients in the CASCADE FH Patient Registry (2017) (1)
- A Phase 3 Randomized Trial Evaluating Alirocumab 300 mg Every 4 Weeks (Q4W) as Monotherapy or Add-On to Statin: ODYSSEY CHOICE I (2016) (1)
- Low HDL and coronary heart disease (1994) (1)
- L5 PHASE 3 STUDY OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR (MTP-I) LOMITAPIDE IN SUBJECTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH): 56-WEEK RESULTS (2010) (1)
- Abstract 13757: Niacin Reverses Increased Plasma PCSK9 Induced by Statin and Fibrate Therapy: A Novel Mechanism for Further LDL Reduction (2012) (1)
- Stress echocardiography in children with homozygous familial hypercholesterolemia predicts severe coronary artery disease (1996) (1)
- ILRUN Promotes Atherosclerosis Through Lipid-Dependent and Lipid-Independent Factors (2022) (1)
- 9 ADIPOKINES IN HUMAN ENDOTOXEMIA (2005) (1)
- 3911Impact of CETP inhibition with evacetrapib in patients with diabetes mellitus: results from ACCELERATE (2017) (1)
- Abstract 444: The Liver-Specific Role of Sortilin in VLDL Secretion (2013) (1)
- SARS-CoV-2 Seropositivity and Seroconversion in Patients Undergoing Active Cancer-Directed Therapy. (2021) (1)
- Multi-trait GWAS of atherosclerosis detects novel pleiotropic loci (2021) (1)
- GENETIC RISK, ADHERENCE TO A HEALTHY LIFESTYLE, AND RISK OF CORONARY ARTERY DISEASE (2017) (1)
- Abstract 19115: Genome-Wide Association Study and Replication Identifies a Novel Genetic Locus for Aortic Stenosis (2017) (1)
- Abstract 681: Treatment With A Potent & Selective PPAR-{alpha} Agonist LY518674 Significantly Increases ApoA-I and ApoA-II Production Rates In Patients With Metabolic Syndrome Despite No Change In HDL (2007) (1)
- Homozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE-FH Registry† (2019) (1)
- Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
- Abstract 19007: Multimodality Blood Flow Imaging in Mice (2017) (1)
- A Single Dose of Extended-Release Niacin Suppresses Postprandial Triglyceridemia in Healthy Volunteers (2009) (1)
- Loci influencing blood pressure identified using a cardiovascular gene-centric array (Correction to Ganesh et al. 22 (8): 1663) (2013) (1)
- Can changes in the plasma lipidome help explain the cardiovascular benefits of the Mediterranean diet? (2017) (1)
- Abstract 17995: Plasma Fibroblast Growth Factor-21 Levels are Positively Associated with Metabolic Syndrome, Insulin Resistance and Systemic Inflammation (2012) (1)
- Importance of Nutritional Intervention for Infants with Abetalipoproteinemia (2019) (1)
- Abstract 120: Effects of Anacetrapib Treatment on CETP Metabolism (2013) (1)
- Abstract 126: Genome Wide Association Study in the Million Veteran Program Identifies a Novel Role for Thrombosis in the Pathogenesis of Peripheral Artery Disease (2018) (1)
- RNA-targeted therapeutics in cardiovascular disease: the time is now. (2022) (1)
- O-081 The effect of DHEA replacement on the endocrine and lipid profiles of perimenopausal women (1997) (1)
- Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations (2019) (1)
- The LDL receptor is not required for normal catabolism of Lp(a) in humans (1994) (1)
- Protection of extreme ultraviolet lithography masks. II. Showerhead flow mitigation of nanoscale particulate contamination (2015) (1)
- Discovery and Refinement Supplementary (2015) (1)
- Therapeutic strategies for the treatment of dyslipidemia (2004) (1)
- Abstract: P469 IMPACT OF HIGH DOSES OF THE MTP-INHIBITOR, AEGR-733, ON THE SINGLE DOSE PHARMACOKINETICS OF ATORVASTATIN AND ROSUVASTAIN (2009) (1)
- P5355Impact of evacetrapib on glyvemic control: results from the accelerate trial (2017) (1)
- Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry. (2023) (0)
- Dietary isoflavone intake modulates evoked responses to cardiometabolic stimuli in healthy volunteers (2013) (0)
- Abstract 19067: Lipoprotein(a) and Risk of Cardiovascular Disease in Persons With Chronic Kidney Disease: Findings From the Chronic Renal Insufficiency Cohort Study (2016) (0)
- EXPERIMENTAL STUDIES OF CHEMICAL REACTIONS INVOLVING SUBMICRON AEROSOLS OF UNIFORM SIZE. (1983) (0)
- Abstract 087: Hepatic Sortilin Regulates Apolipoprotein B Secretion only Under Conditions of Secretory StressDependent of the Presence of Secretory Stress (2018) (0)
- Effect of Atorvastatin on Lipid Profiles Following Heart Transplantation (1999) (0)
- Running title: Stitziel et al., Exome Sequencing in Monogenic Dyslipidemias (2015) (0)
- Abstract 358: Genetic Determinants of Lower-Extremity Claudication in South Asians (2014) (0)
- Abstract 332: Deletion of ADAMTS7 in Mice Reveals a Role in Vascular Smooth Muscle Cell Response to Injury (2012) (0)
- COMMENT s the Cholesteryl ster Transfer Protein roatherogenic or ntiatherogenic in Humans ? * (2007) (0)
- Homocysteine and Vascular Disease (1999) (0)
- The Role of HDLC in the Management of Atherosclerosis Moderated (2012) (0)
- Abstract 387: Regulation of Apolipoprotein B Secretion by Hepatic Sortilin is Dependent on Secretory Stress (2016) (0)
- Eukaryotic Fatty Acid Resistance Product as a Major Component of ) Gene ARV 1 Required for Viability ' ' ( ARE 2 Liposensitive Yeast Identifies the ' ' A Functional , Genome-wide Evaluation of Membrane Biology (2014) (0)
- Abstract 233: Genetic Evidence for Overlap in the Pathogenesis of Peripheral Artery Disease and Coronary Artery Disease (2017) (0)
- Evinacumab in severe hypertriglyceridemia with or without lipoprotein lipase pathway mutations: a phase 2 randomized trial (2023) (0)
- GENOTYPE-FIRST APPROACH SHOWS FOG2/ZFPM2 IS ASSOCIATED WITH CORONARY MICROVASCULAR DISEASE (2019) (0)
- Abstract 13230: Convergence of CXCL12 and PHACTR1: Novel Genome Wide Signals for Myocardial Infarction Regulate Plasma CXCL12 Levels (2010) (0)
- Measuring Physical Stigmata of Niacin-Associated Skin Toxicity by Colorimetry , White-Light Spectroscopy , Laser Doppler Flowmetry , and Thermometry in Combination with Symptom Perception Scoring : Methods to Aid Development of Niacin Mimetics (2017) (0)
- Intracoronary Imaging, Reverse Cholesterol Transport, and Transcriptomics (2017) (0)
- Experimental demonstration of particle focusing and impaction in an opposed-flow virtual cyclone. (2004) (0)
- Effects of lipoprotein apheresis (la) on serum pcsk9 levels (2014) (0)
- Lipoprotein(a) and Oxidized Phospholipids: Partners in Crime or Individual Perpetrators in Cardiovascular Disease? (2023) (0)
- Abstract P401: Associations Between High-density Lipoprotein Subclasses and Coronary Artery Calcification Vary by Menopausal Stage. The Study of Women's Health Across the Nation Hdl Ancillary Study (2020) (0)
- Nanoparticle Aerosols Form Knudsen Layers at Walls (2009) (0)
- Abstract 414: In Hyperalphalipoproteinemic Subjects, the Presence of Coronary Artery Disease is Associated With Marked Changes in the High-Density Lipoprotein Phosphosphingolipidome (2014) (0)
- Coronary artery disease-protective A43T variant in APOC3 alters circulating ApoC-III levels in vivo (2015) (0)
- In vivo kinetics of a mutant protein, APO A-I IOWA (1992) (0)
- Early Midlife Cardiovascular Health Influences Future HDL Metrics in Women: The SWAN HDL Study (2022) (0)
- Considerations relating to pulsed-beam modification of materials (1990) (0)
- 4WS26-6 Endogenously expressed endothelial lipase modifies transport of free and esterified cholesterol between HDL and cells (2003) (0)
- The role of TTC39B in atherosclerosis and non-alcoholic steatohepatitis. (2017) (0)
- Abstract 126: Identification of an Individual With Extremely High HDL-C Who is Homozygous for a Loss-of-function Mutation in Scavenger Receptor BI (SR-BI) and Functional Characterization of the Mutation (2013) (0)
- Abstract MP16: Multi-trait Gwas Of Atherosclerosis Detects Novel Loci And Potential Therapeutic Targets (2021) (0)
- Noncontinuum Effects in Gas-Phase Heat Transfer in Microdevices (2005) (0)
- Contents Vol. 25, 2005 (2005) (0)
- 2003 Mixed meal effects of neprilysin inhibition (2018) (0)
- Abstract P066: Associations Between Coronary Artery Calcium and HDL Particle Characteristics in MESA Participants with Very-High Levels of HDL Cholesterol (>80mg/dL) (2013) (0)
- Dyslipidemia Profile in Cholesteryl Ester Storage Disorder (2013) (0)
- Abstract 18321: Analysis of a Consanguineous Cohort to Identify and Characterize Human Knockouts (2015) (0)
- Mo-W3:5 A carboxyterminal region of endothelial lipase is a binding site for HDL (2006) (0)
- University of Groningen Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Tragante, (2014) (0)
- Human genetics shines a light on ischaemic stroke (2016) (0)
- Abstract 329: Mechanism by Which Anacetrapib Lowers Plasma Lipoprotein (a) Concentration (2012) (0)
- Abstract 17565: High-Throughput Analysis of Full-Text Cardiac Catheterization Reports Using Open-Source Natural Language Processing and Machine Learning Tools (2017) (0)
- PLASMA APOC-III LEVELS, TRIGLYCERIDES, AND CORONARY ARTERY CALCIFICATION IN TYPE 2 DIABETICS (2015) (0)
- EFFECT OF CONTINUOUS-POSITIVE AIRWAY PRESSURE, WEIGHT LOSS OR BOTH ON PERIPHERAL AND CENTRAL BLOOD PRESSURE IN OBESE SUBJECTS WITH OBSTRUCTS SLEEP APNEA (2013) (0)
- ORAL ABSTRACT PRESENTATIONS S-1. Evaluation of a Discussion Guide to Promote Understanding of Menopause and Informed Decision Making (2020) (0)
- CHANGES IN HOMOCYSTEINE CONCENTRATION AFTER ORTHOTOPIC HEART TRANSPLANTATION (1998) (0)
- Chapter 45 – Lipoprotein Disorders (2013) (0)
- Familial Chylomicron Syndrome: Importance of Discerning the Rare Among the Common (2017) (0)
- Lipoprotein(a) and Risk of Myocardial Infarction and Death in Persons with Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study (2017) (0)
- Abstract 190: Classic Lipid and Novel Inflammatory Phenotypes in an Induced Pluripotent Stem Cell--Derived Macrophage Model of Tangier Disease (2014) (0)
- Syddansk Universitet Variant ASGR1 associated with a reduced risk of coronary artery disease (2016) (0)
- Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program (2018) (0)
- Abstract 14363: Genetics of Coronary Atherosclerotic Plaque Rupture and Myocardial Infarction (2010) (0)
- 768 The Relationship Between Circadian Rhythm and Autism Spectrum Disorder Traits and Executive Function Across the Life Span (2021) (0)
- Abstract 5054: Apolipoprotein B, but not Low-Density Lipoprotein Cholesterol is Associated with Coronary Atherosclerosis Beyond Total Cholesterol in Diabetics and Non-Diabetics (2008) (0)
- P-172 Association of high density lipoprotein with MCI and verbal memory in an ethnically diverse cohort (2007) (0)
- Microscale Gas-Surface Interactions (2004) (0)
- Abstract 16736: The Long Intergenic Non-coding RNA Landscape in Human Macrophage Activation (2016) (0)
- Supplementary Material (nature09270-s1) (2012) (0)
- Abstract 71: AAV-Mediated Expression of Human IDOL in Mouse Liver Increases LDL Cholesterol in a Dose-Dependent Fashion (2014) (0)
- Pre-transplant Macrophage Cholesterol Efflux Capacity is Associated With Angiographic Cardiac Allograft Vasculopathy in a Multi-center Observational Study (2018) (0)
- Contents Vol. 33, 2011 (2011) (0)
- Abstract 1182: Inflammation Impairs Reverse Cholesterol Transport in vivo (2007) (0)
- Inverse Correlation of Cholesterol Efflux Capacity of High Density Lipoprotein With Survival After Cardiac Transplantation.: Abstract# B1252 (2014) (0)
- Abstract 18960: RNA-binding Protein A1CF Modulates Plasma Triglyceride Levels Through Transcriptomic Regulation of Stress-Induced VLDL Secretion (2017) (0)
- Abstract 455: Role of Transcription Co-Factor Friend of GATA 2 (FOG2) in a Hypertensive-Diabetic Mouse Model of Coronary Microvascular Disease (2018) (0)
- Abstract 16: Tribbles1 Regulates Hepatic Lipogenesis in Mice through Post-Translational Regulation of C/EBPα (2015) (0)
- High velocity electromagnetic particle launcher for aerosol production studies (1986) (0)
- Abstract 19434: Smaller Ldl Peak Diameter is Causally Associated With Higher Risk of Coronary Heart Disease (2016) (0)
- Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis (2020) (0)
- Abstract 574: A Role for TWIST1 as GWAS Risk Gene for Coronary Artery Disease (2016) (0)
- UTILIZING RUBIDIUM-82 CARDIAC POSITRON EMISSION TOMOGRAPHY REGIONAL MYOCARDIAL BLOOD FLOW TO DEVELOP NAIVE BAYES CLASSIFIER FOR CORONARY ARTERY DISEASE PREDICTION (2019) (0)
- Targeting ASGR1 to lower cholesterol (2022) (0)
- Abstract 13310: Anti-Inflammatory HDL Function and Incident Cardiovascular/Death Events: A Secondary Analysis of the JUPITER Trial (2018) (0)
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants Myocardial Infarction Genetics Consortium * (2009) (0)
- Abstract 17862: Protection From Acute Myocardial Infarction in Humans is Associated With a Genetic Variation Near a Novel Gene Encoding a Human Protein Binding to a Mouse Model of Vulnerable Plaque (2010) (0)
- Abstract 20280: Impact of the Cholesteryl Ester Transfer Protein Inhibitor Evacetrapib on Cholesterol Efflux Capacity in High Risk Patients Within the ACCELERATE Trial (2016) (0)
- Clinical Use of Apolipoprotein Quantitation (1995) (0)
- Insulin Resistance : Should We Incorporate Measures of Insulin Resistance Into Clinical Practice ? (2003) (0)
- Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study. (2023) (0)
- Extracellular calcium concentration influences lysosomal behavior in the in vitro xenotransplant hyperacute rejection model. (1997) (0)
- Genome-wide association meta-analysis in 652,134 participants identifies 9 novel susceptibility loci for aortic stenosis (2020) (0)
- The Role of Emerging Biomarkers in Unraveling the Complex Biology Underlying Associations between HDL Cholesterol and Cardiovascular Diseases. (2017) (0)
- Coronary Artery Disease Candidate Gene Association Study of Coronary Artery Calcification in Chronic Kidney Disease FindingsFromtheCRICStudy ( ChronicRenal Insuf fi ciencyCohort ) (0)
- Abstract P101: Premenopausal Life’s Simple 7 Score Is Associated With High-density Lipoprotein Metrics Later In Life: The SWAN HDL Study (2021) (0)
- Abstract 13601: Risk of Coronary Artery Disease Associated With Familial Hypercholesterolemia Genetic Variants is Independent of Historical Low-density Lipoprotein Cholesterol Exposure (2020) (0)
- Abstract 11298: Absence of Rare Coding Sequence Variants of Large Effect in GWAS Loci for High-Density Lipoprotein Cholesterol (2013) (0)
- University of Groningen Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (0)
- Laboratory and Field Studies of Gas-Aerosol Reactions (1986) (0)
- The Effects of a Microsomal Triglyceride Transfer Protein Inhibitor on Fat Soluble Compounds (2007) (0)
- Abstract 405: Functional Characterization of Coronary Artery Disease (CAD) Associated SNPs at the ADAMTS7 Locus (2015) (0)
- Review Gene therapy for lipid disorders (2000) (0)
- Safety, Health and Environment (2014) (0)
- CSL112, A NOVEL FORMULATION OF HUMAN APOA-I, ROBUSTLY ENHANCES THE ABILITY OF SERUM TO EFFLUX CHOLESTEROL (2012) (0)
- Annular-beam laser for in situ particle sizing/velocimetry (1998) (0)
- Literature Survey Of Lcat Deficiency: Natural History And Biomarker Identification (2019) (0)
- Abstract 5: Sortilin Regulates Hepatic VLDL Secretion and LDL Uptake in a Lysosome-Dependent Manner (2012) (0)
- CLINICAL USE, INSURANCE APPROVAL, AND LIPID LOWERING OF PCSK9 INHIBITORS IN A LARGE HEALTH SYSTEM (2020) (0)
- Glucose metabolism in plaque macrophage: Molecular mechanism for FDG-PET imaging of atherosclerosis (2009) (0)
- Th-P15:214 Characterization of bone marrow-derived macrophages for studies of cholesterol efflux in vitro and reverse cholesterol transport in vivo (2006) (0)
- EFFICACY AND SAFETY OF THE PCSK9 INHIBITOR ALIROCUMAB 300 MG EVERY 4 WEEKS IN INDIVIDUALS WITH TYPE 2 DIABETES ON MAXIMALLY TOLERATED STATIN THERAPY (2017) (0)
- Stage response of an Andersen cascade impactor to monodisperse droplets (1989) (0)
- Burden of genetic testing in an academic biobank by pathological and family history-based criteria in prostate cancer (PCa). (2020) (0)
- Abstract 116: A Targeted Sequencing Approach in Subjects with Extremely High HDL-C Identifies individuals with Potentially Causal Mutations in Both Alleles of 53 Genes (2013) (0)
- Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes (2018) (0)
- Abstract 19506: Relevance of Fibroblast Growth Factor 21 in Cardio-metabolic Diseases (2015) (0)
- Abstract 498: A Single Nucleotide Polymorphism in the CDKN1B Gene is Associated With Carotid Plaque Progression (2014) (0)
- Monocyte chemoattractant protein-1 promotes macrophage oxidation of low density lipoprotein (2000) (0)
- Rare sequence variants that disrupt ASGR 1 function lower non-HDL cholesterol and protect against coronary artery disease (2016) (0)
- Abstract: 1060 UPDATE ON CETP INHIBITION (2009) (0)
- Abstract 465: Deciphering the Genetic Regulation of ADAMTS7, a Novel Locus for Coronary Artery Disease (2014) (0)
- Abstract 1611: PPAR {alpha} Agonism Promotes Reverse Cholesterol Transport in a Macrophage PPAR {alpha} and Liver X Receptor Dependent Manner (2009) (0)
- Sex differences regarding the effect of dietary vitamin E on the liver and metabolic profile. (2023) (0)
- Antisense oligonucleotides for atherosclerotic disease (2020) (0)
- Abstract 567: Causal Assessment of Uric Acid and Risk of Myocardial Infarction, a Mendelian Randomization Study (2013) (0)
- Contents (2020) (0)
- Enhancing Atherosclerosis Regression in Diabetic Mice Through Apo AI (Apolipoprotein AI). (2019) (0)
- Abstract: 612 ROLE OF ENDOTHELIAL LIPASE IN HUMAN PHYSIOLOGY (2009) (0)
- 9. AAV-Mediated Gene Transfer as a Therapeutic Approach for Familial LCAT Deficiency (2015) (0)
- The development of CETP (cholesteryl Trials and Tribulations of CETP Inhibitors (2017) (0)
- Cholesterol and all-cause mortality in Honolulu (2001) (0)
- Web of Science’s Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor (2022) (0)
- Abstract 20468: Regional Myocardial Blood Flow Variability Is Associated With the Presence of Coronary Artery Disease in Clinical Rubidium-82 Cardiac Positron Emission Tomography (2016) (0)
- PPP1R3B is a metabolic switch that shifts hepatic energy storage from lipid to glycogen (2023) (0)
- Improving Outcomes in Patients with Severe Familial Hypercholesterolemia (2012) (0)
- Short title: Musunuru et al; Design of NHLBI CARe (2017) (0)
- Abstract P2001: Vessel Normalization By Targeting Endothelial Cell Plasticity To Improve Cardiac Repair After Myocardial Infarction (2022) (0)
- Lipids and Guidelines -- "Let Me Be Simple-Minded Doctor!!" LDL-C Less Than 70 mg/dL and Pay Attention to HDL (2020) (0)
- Characteristics of Patients in the 10th and 90th Percentile of LDL-C Reductions with Alirocumab: ODYSSEY Pooled Analyses (2018) (0)
- Using the Direct Simulation Monte Carlo (DSMC) Method to Determine the Force on and Heat Transfer to a Spherical Particle in a Rarefied Gas Flow (2001) (0)
- Vascular protection of ace inhibitors. Authors'reply (2003) (0)
- Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations (2019) (0)
- Abstract 367: Extreme High-Density Lipoprotein Cholesterol Genetics: An Assortment of Large and Small Polygenic Effects (2017) (0)
- Abstract 332: Coronary Artery Disease-Protective Variant A43T in APOC3 Alters Circulating ApoC-III Levels In vivo (2015) (0)
- Familial Hypercholesterolemia: Challenges for a High-Risk Population: JACC Focus Seminar 1/3. (2023) (0)
- W09-P-012 ApoA-I is required for HDL anti-atherogenic function in vivo (2005) (0)
- Translating HDL Science to Clinical Practice (2011) (0)
- Abstract 15464: Serum CXCL12 Levels Decrease Following Acute Myocardial Infarction - Data from the Pakistan Risk of Myocardial Infarction Study (PROMIS) (2011) (0)
- 4365 Family-Based Study of Sleep in Autism Spectrum Disorder without Intellectual Disability (2020) (0)
- Letter to the Editor in response to “Response to Kovanen PT, et al. Letter to the Editor” for original article COVID-19 increases risk of myocardial infarction in persons with familial hypercholesterolemia with or without ASCVD (2021) (0)
- Abstract 157: Alternative Splicing of PLD1 and Its Role in Modulating Inflammatory Phenotypes in Primary Human Macrophages (2016) (0)
- Electromagnetic launcher studies of breakup and aerosol formation in molten uranium alloy (1990) (0)
- Multiplexed targeted resequencing identifies coding and regulatory variation underlying phenotypic extremes of HDL-cholesterol in humans (2017) (0)
- Abstract: S3-35 CHOLESTEROL FLUX BETWEEN CELLS AND LIPOPROTEINS (2009) (0)
- Abstract 4093: CXCL16 is Marker of Inflammation, Atherosclerosis and Acute Coronary Syndromes in Humans (NPAM Young Investigator Awardee) (2006) (0)
- Gene Sequencing in US Patients with Severe Clinical Familial Hypercholesterolemia (2014) (0)
- Novel cardiovascular disease (CVD) risk factors elevated in young women with PCOS – possible link between NEFA and androgens identified (2012) (0)
- Diagnosing Familial Hypercholesterolemia (FH) in the United States: Results from the CASCADE FH Patient Registry*† (2015) (0)
- CHAPTER 55 – Lipoprotein Disorders (2009) (0)
- Abstract 449: Expression of Type IIA Secretory Phospholipase A 2 (sPLA 2 ) Inhibits Cholesteryl Ester Transfer Protein (CETP) Activity in Transgenic Mice (2013) (0)
- Associations of abdominal and cardiovascular adipose tissue depots with HDL metrics in midlife women: The SWAN Study. (2022) (0)
- Apolipoprotein B mRNA Editing: Modulation and Clinical Implications (1993) (0)
- Clinical Management of Elevated Lipoprotein(a) in A Large Cohort of Familial Hypercholesterolemia Patients (2019) (0)
- Abstract: P1297 THE LOW SERUM MAGNESIUM OF METABOLIC SYNDROME IS ASSOCIATED WITH INCREASED INTRACELLULAR MAGNESIUM RATHER THAN DEFICIENCY (2009) (0)
- Nanoparticle Knudsen Layers in Gases (2007) (0)
- Abstract 390: Perilipin 1 (plin1) Genotype and Not Gpr109a Associated with Free Fatty Acid Rebound Following Niacin Administration (2013) (0)
- The Molecular Basis of Genetic Defects in HDL Metabolism (1993) (0)
- APOLIPOPROTEIN J/CLUSTERIN IS THE PRIMARY DETERMINANT OF THE CHOLESTEROL EFFLUX CAPACITY OF CEREBROSPINAL FLUID (2018) (0)
- DSMC Simulations of Transient Microbeam Gas Flow (2004) (0)
- Abstract # 10083: From Genotype to Phenotype at a Novel Cholesterol and Myocardial Infarction Locus (2010) (0)
- Abstract P105: Associations Of Subclasses, Content And Function Metrics Of High-density Lipoprotein With Carotid Intima-media Thickness In Women Transitioning Through Menopause Swan Hdl And Swan Heart Studies (2021) (0)
- COVID-19 outcomes and the human genome (2020) (0)
- Apolipoprotein E-Deficient Mice Results in Reduced Atherosclerosis in Deficiency in Inducible Nitric Oxide Synthase (2000) (0)
- Author response: A Mendelian randomization study of the role of lipoprotein subfractions in coronary artery disease (2021) (0)
- TRIPLE THERAPY WITH STATIN, FIBRATE (TRILIPIX) AND NIACIN RAISES HIGH-DENSITY LIPOPROTEIN CHOLESTEROL WITHOUT CHANGING APOLIPOPROTEIN A-I LEVELS (2010) (0)
- Hepatic Manifestations of Mendelian Disorders of Cholesterol Biosynthesis and Cellular Metabolism (2021) (0)
- 1008-184 The effects of pravastatin and atorvastatin on markers of oxidant stress in vivo (2004) (0)
- Polygenic Risk Score Identifies Patients at Increased Risk for Abdominal Aortic Aneurysm and May Benefit from Ultrasound Screening (2020) (0)
- Impaired in vivo metabolism of HDL in familial hypercholesterolemia (1993) (0)
- Abstract 16710: CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention (PCI) in the Million Veterans Program (MVP) (2020) (0)
- Mo-W1:1 Effects of cholesteryl ester transfer protein inhibition on lipoprotein metabolism in humans (2006) (0)
- Abstract 691: Arv1 Deletion Alters Fat Storage via Adipose-Extrinsic Mechanisms (2015) (0)
- CETP , Lipoprotein Metabolism , and Atherosclerosis in Humans Genetic CETP Deficiency in Humans and Effects on Lipoprotein Metabolism (2003) (0)
- Abstract 17038: Twist1 Modulates Smooth Muscle Cell Phenotypes in Atherosclerosis (2018) (0)
- Abstract 170: Statin Therapy Increases Plasma Levels of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Hypercholesterolemic Subjects (2012) (0)
- Application of boundary element techniques to the motion of aerosol particles (1992) (0)
- Abstract 1086: Biliary Sterol Secretion is Required for Functional in vivo Reverse Cholesterol Transport (2009) (0)
- The V122I Variant in Hereditary Transthyretin-Mediated Amyloidosis is Significantly Associated with Polyneuropathy (2020) (0)
- Characterization of the lipid efflux pathways in RPE (2017) (0)
- Tu-S8:3 Modification of cardiovascular risk factors: Clinical benefits (2006) (0)
- Apheresis Treatment did not Impact the Efficacy of Lomitapide in Patients with Homozygous Familial Hypercholesterolemia: Results from the Pivotal Phase† (2013) (0)
- Abstract 482: Peroxisome Proliferator-Activated Receptor α Modulation with Fenofibrate Does Not Alter the Clinical or Inflammatory Responses to Evoked Endotoxemia in Humans (2012) (0)
- Anti-Inflammatory and Antioxidant Functions of High Density Lipoproteins (2006) (0)
- Exome-wide evaluation of rare coding variants using electronic health records identifies new gene–phenotype associations (2021) (0)
- 0974 Family-Based Study Of Sleep In Autism Spectrum Disorder Without Intellectual Disability (2020) (0)
- Effect of increasing doses of micronized fenofibrate on post-prandial triglycerides and fasting plasma lipids and lipoproteins in hypertriglyceridemic patients (2000) (0)
- Convergence Behavior of Bird's Sophisticated DSMC Algorithm (2007) (0)
- ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer’s disease (2022) (0)
- CHAPTER 45 – Therapeutic Targeting of High-Density Lipoprotein Metabolism (2009) (0)
- Abstract 219: Role of Transcription Co-Factor Friend of GATA 2 (FOG2) in a Hypertensive-Diabetic Mouse Model of Coronary Microvascular Disease (2018) (0)
- Abstract 868: Prevalence, Underdiagnosis, and Undertreatment of Cardiovascular Risk Factors in Patients With Moderate-to-Severe Psoriasis (2009) (0)
- The HDL Quandary (2020) (0)
- An Electronic Health Records Query for Severe Hypercholesterolemia Identifies Individuals With Undiagnosed Clinical and Molecular FH at a Tertiary Academic Centre (2017) (0)
- Abstract 17067: Circulating Lipoprotein (a) Level, Apolipoprotein (a) Isoform Size, and Risk of Unexplained Ischemic Stroke in Younger Adults (The THrombophilia in Cryptogenic stroKe [THICK] Study) (2014) (0)
- Abstract 20145: Multiple Novel Plasma Biomarkers are Associated With Aortic Stenosis (2016) (0)
- Edinburgh Research Explorer The role of survival motor neuron protein (SMN) in protein homeostasis (2018) (0)
- Consultants for the American Journal of Nephrology 2005 (2005) (0)
- Familial Hypercholesterolemia: Gene Therapy (2006) (0)
- Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Historical Cholesterol Exposure (2020) (0)
- Abstract 115: Trib1 Hepatic Deficiency Impairs Low Density Lipoprotein Cholesterol Clearance, and Raises Plasma Lipids Through Both Low Density Lipoprotein Receptor Dependent and Independent Mechanisms (2019) (0)
- Abstract 364: Modulation of Novel Long Intergenic Noncoding RNAs in Human Macrophage Polarization (2014) (0)
- A coding variant in SR-BI (I179N) significantly increases atherosclerosis in mice (2013) (0)
- Edinburgh Research Explorer Efficacy and safety of lipid lowering by alirocumab in chronic kidney disease (2018) (0)
- Therapeutic Targeting of High‐Density Lipoproteins (2007) (0)
- 4P-1026 Apolipoproteins regulate the remodelling of high density lipoproteins by endothelial lipase (2003) (0)
- Abstract 348: TNFα-induced Expression of Adamts7 Affects Primary Mouse Smooth Muscle Cell Migration ex vivo (2015) (0)
- Experimental Determination of Thermal Accommodation Coefficients in a Parallel-Plate Geometry. (2007) (0)
- Association of Chromosome 9p21.3 with Disease Location, Including the Number of Diseased Vessels, but not with Greater Burden of Coronary Disease (2013) (0)
- Chapter 313 CHAPTER 8 DISORDERS OF LIPOPROTEIN METABOLISM (0)
- In Vivo Metabolism of a Mutant Apolipoprotein A-I (ARG-26) Associated with Hereditary Amyloidosis (1991) (0)
- Abstract 329: CRISPR/Cas-mediated Gene Editing in Human iPSC-derived Macrophage Reveals Lysosomal Acid Lipase Functions in Human Macrophages (2015) (0)
- Challenges in Interpreting Genetic Reports in Familial Hypercholesterolemia: Variants of Uncertain Significance (2017) (0)
- Assessment of statin therapy guidelines in cardiac transplant patients (2001) (0)
- A deleterious mutation in scarb1 significantly alters HDL level, composition, and biological function in humans (2014) (0)
- Edinburgh Research Explorer Secretory Phospholipase A2-IIA and Cardiovascular Disease (2018) (0)
- Abstract 627: A Deleterious Mutation in SCARB1 Significantly Alters High-Density Lipoprotein Level, Composition and Biological Function in Humans (2014) (0)
- Metabolic effects of guggulipid: results from a randomised controlled trial (2010) (0)
- Deficient Mice − Normal Production Rate of Apolipoprotein B in LDL Receptor (2002) (0)
- LACK PREDICTIVE UTILITY IN END STAGE RENAL DISEASE (2018) (0)
- Role of CETP in the Development of Atherosclerosis in Animals Expression of CETP in Transgenic Mice (2003) (0)
- HDL Functionality: How Do We Measure It and Is It Relevant for Everyday Clinical Practice? (2011) (0)
- Revisiting Genome Sequencing Data in Light of (0)
- Abstract: P470 EFFICACY, SAFETY AND TOLERABILITY OF THE MTP INHIBITOR AEGR-733 COMBINED WITH ATORVASTATIN (2009) (0)
- Aerosol formation from high-velocity uranium drops: Comparison of number and mass distributions. Final report (1995) (0)
- Abstract 21: Sortilin Is a Novel Mediator of Cellular Low-Density Lipoprotein Uptake (2012) (0)
- Abstract 14579: Hepatic TRIB1 Regulates ApoB Metabolism by Modulating Its Production and Catabolism (2019) (0)
- Abstract 13073: Chr10q11 Atherosclerosis Locus Modulation of Plasma and Adipose CXCL12 to in vivo Inflammation (2011) (0)
- Abstract 668: Whole Body and Hematopoietic Sortilin Deficiency Reduces Atherosclerosis in Mice Independent of Effects on LDL Cholesterol (2014) (0)
- The response of the aerodynamic particle sizer to nonspherical particles and use in experimental determination of dynamic shape factor (1989) (0)
- Percentage Lipid Composition of VLDL , IDL , and LDL Fractions During the Placebo and 120 mg Torcetrapib (2006) (0)
- Human Plasma Apolipoproteins A-IV-O and A-IV-3 (2001) (0)
- Abstract P109: Hypertension in a Large Cohort of Patients With Lipoprotein(a) at a Tertiary Academic Center (2019) (0)
- Normal Solutions of the Boltzmann Equation for Fourier and Couette Flow (2005) (0)
- The plasma proteome of tangier disease patients reveals perturbations of diabetic and inflammatory pathways (2016) (0)
- The Role of the Beta5 Loop of Endothelial Lipase in the Hydrolysis of Reconstituted High-Density Lipoprotein Phospholipids (2005) (0)
- Angiopoietin-like Protein 3 Inhibits Lipoprotein Lipase Activity through Enhancing Its Cleavage by Proprotein Convertases * □ S (2020) (0)
- Cholesterol efflux capacity inversely correlates with HDL cholesterol fractional catabolic rate (2015) (0)
- Does myeloid expression of TRIB1 regulate plasma lipid levels (2015) (0)
- mTOR signaling in adipose tissue influences systemic lipid metabolism (2018) (0)
- Abstract 9542: HDL is Dysfunctional in Patients with Ischemic Cardiomyopathy (2012) (0)
- Abstract 18159: Transcriptomic Profiling of Isogenic PBMC-derived and iPSC-derived Macrophages and Their Polarization (2014) (0)
- Effects of Novel Biologics to Treat Hypertriglyceridemia in Familial Chylomicronemia Syndrome with Two Different Genotypes (2020) (0)
- Abstract 540: Correlation of Improved Cholesterol Efflux Capacity of High Density Lipoprotein With Survival and Allograft Vasculopathy in Cardiac Transplant Recipients (2015) (0)
- Abstract 20: Tribbles1 (Trib1) is a Novel Regulator of in vivo Hepatic Fatty Acid Lipogenesis in the Mouse. (2013) (0)
- Errata (2011) (0)
- Exome-wide association studies in general and long-lived populations identify genetic variants related to human age (2020) (0)
- Abstract 18832: Trans-ethnic Genome-wide Association Study of Peripheral Artery Disease in the VA Million Veteran Program (2017) (0)
- DSMC Simulations of Transiently Decaying Shear Flow (2006) (0)
- Lack of pathogenic germline DICER1 variants in males with testicular germ-cell tumors. (2020) (0)
- A genome-first approach to aggregating rare genetic variants in LMNA for association with electronic health record phenotypes (2019) (0)
- Proprotein convertases are responsible for proteolysis and inactivation of endothelial lipase. VOLUME 280 (2005) PAGES 36551-36559 (2005) (0)
- Strategies for Early Detection: The Role of Genetic Testing in Patients with Severe Hypercholesterolemia (2012) (0)
- Gene burden analysis identifies genes associated with increased risk and severity of adult-onset hearing loss in a diverse hospital-based cohort (2023) (0)
- Generation of aerosolized particulate contamination by the wear of stainless steels (1992) (0)
- Novel therapeutic opportunities for familial lecithin:cholesterol acyltransferase deficiency: promises and challenges (2022) (0)
- Comparison of the structure-function properties of wild-type human apoA-V and a C-terminal truncation associated with elevated plasma triglycerides (2023) (0)
- Implementation of Flag, Identify, Network, Deliver (FIND FH) Machine Learning Algorithm: A Quality Improvement Initiative to Perform Targeted Screening for Familial Hypercholesterolemia within a Single Healthcare System (2020) (0)
- Subject Index Vol. 25, 2005 (2005) (0)
- 123 Myeloid TRIB1 controls experimental atherosclerosis (2018) (0)
- Abstract 16668: Serum Gamma Glutamyl Transferase and Risk of Coronary Artery Disease: A Causal Assessment by Mendelian Randomization (2013) (0)
- Disease Presenting as Autosomal Recessive Hypercholesterolemia Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage (2013) (0)
- Abstract 2260: On-treatment Cholesteryl Ester Transfer Protein Mass and Risk for MI in the PROVE-IT Study (2006) (0)
- Familial Chylomicronemia Syndrome: Distinguishing the Rare Among the Common in Adults for Appropriate Management† (2019) (0)
- Abstract 20318: Elevated Levels of Lipoprotein(a) Are Causally Associated With Chronic Kidney Disease (2014) (0)
- Polygenic risk scores for dyslipidemia and atherosclerotic cardiovascular disease: progress toward clinical implementation (2022) (0)
- Abstract 558: CETP Inhibitor Increases HDL-C and Cholesterol Efflux Capacity, but Reduces Subsequent Cholesterol Esterification and Hepatic Cell Uptake (2019) (0)
- A loss-of-function mutation in scarb1 severely impairs sr-bi processing and activity in humans (2014) (0)
- Th-P15:20 Thiazolidinediones inhibit endothelial lipase expression in cultured endothelial cells and human plasma (2006) (0)
- Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci (2022) (0)
- ASSOCIATION OF CORONARY RISK FACTORS WITH PROXIMAL AND DISTAL ATHEROSCLEROSIS (2010) (0)
- Abstract 200: Functional Mapping of the 8q24 Noncoding Region Reveals Enhancer Elements and Association Between GWAS SNPs and TRIB1 Gene Expression (2017) (0)
- The V122I Mutation in Hereditary Transthyretin-Mediated Amyloidosis is Significantly Associated with Polyneuropathy (2019) (0)
- SAI-24: Longitudinal study of lipid-modifying therapies on carotid atherosclerotic plaque morphology in vivo using magnetic resonance imaging (2001) (0)
- A Phase 3 Study of the Microsomal Triglyceride Transfer Protein (MTP) Inhibitor Lomitapide in Patients with Homozygous Familial Hypercholesterolemia (2012) (0)
- Abstract 022: Hepatic Sortilin Regulates Apolipoprotein B Secretion only Under Conditions of Secretory StressDependent of the Presence of Secretory Stress (2018) (0)
- ATVB In Focus Novel Approaches to the Treatment of Dyslipidemia (2005) (0)
- Systematically Sifting Big Data to Identify Novel Causal Genes for Human Traits. (2020) (0)
- 103: Changes in Core Temperature Are Related to Free Fatty Acid Rebound from Niacin (2008) (0)
- OR21-3 Familial Chylomicronemia Syndrome: Distinguishing the Rare Among the Common in Adults for Appropriate Management (2019) (0)
- Abstract 13093: Height as a Causal Risk Factor for Atrial Fibrillation: A Mendelian Randomization Study (2019) (0)
- Contrasting Postprandial Triglyceride Response of Two Niacin Formulations and Regimen To Modify Coronary Heart Disease Risk (2020) (0)
- Modeling of Brownian Dynamics with DSMC Using the Langevin Equation (2001) (0)
- Abstract 121: Exploiting Natural Genetic Variation In The Human Triglyceride Regulator APOA5 To Understand Its Function (2021) (0)
- Abstract 16398: Effect of CETP Inhibition With Anacetrapib on VLDL Triglyceride and Plasma ApoC-II, ApoC-III and ApoE Metabolism (2016) (0)
- Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications (2023) (0)
- Abstract 16536: Implementation Of Flag, Identify, Network, Deliver: Find FH Using The Electronic Medical Record To Identify Familial Hypercholesterolemia Within A Single Healthcare System (2019) (0)
- Tu-W23:5 Intravenous administration of large unilamellar vesicles and Apo AI/Phospholipid complexes increases free cholesterol in plasma by different mechanism (2006) (0)
- Angiopoietin-likeProtein3InhibitsLipoproteinLipaseActivity throughEnhancingItsCleavagebyProproteinConvertases *□ (2010) (0)
- In hyperalphalipoproteinemic subjects, the presence of coronary artery disease is associated with marked changes in the HDL phosphosphingolipidome (2014) (0)
- Abstract 705: Investigating the Clinical Presentation and Progression of Familial LCAT Deficiency: An Analysis of the Literature (2019) (0)
- An Improved-Efficiency DSMC Algorithm. (2008) (0)
- SAT-578 A Rare Case of Laboratory Hypertriglyceridemia: Glycerol Kinase Deficiency (2020) (0)
- Abstract 3705: Pioglitazone Augments Niacin-Induced Increases in Adiponectin in Non-Diabetics with Metabolic Syndrome and Low HDL (2008) (0)
- Abstract 18477: Understanding the Causal Relevance of Apo(a) Isoform Size, Lipoprotein (a) and Oxidized Phospholipids in Coronary Heart Disease (2016) (0)
- Abstract 5097: High Density SNP Association Analysis of Potential HDL Candidate Genes Reveals Molecular Architecture and Functionally Relevant Domains: Focus on CETP (2008) (0)
- Thyroid hormone binding to isolated human apolipoproteins A-II, C-I, C-II, and C-III: homology in thyroxine binding sites. (1994) (0)
- Abstract 132: Risk Factors for Lower-Extremity Claudication in South Asians (2014) (0)
- Abstract 5522: Niacin Increases HDL Through Reduced Phospholipase A1 Activtiy And CETP mRNA Stability In The Mice Expressing Human ApoA-I And CETP (2008) (0)
- Abstract 1618: High-Density Lipoprotein Cholesterol but Not Apolipoprotein A-I or -II is Associated With Coronary Calcium in Type 2 Diabetes (2009) (0)
- PLASMA BIOMARKERS FOR RISK STRATIFICATION OF OUTCOMES IN PATIENTS WITH AORTIC STENOSIS (2021) (0)
- Glypican- versus Syndecan-Mediated Ligand Catabolism in vitro. Side-by-Side Comparison (2006) (0)
- Abstract 115: Microsomal Triglyceride Transfer Protein Is a Major Determinant of Plasma Ceramide And Sphingomyelin but Not of Hexosylceramide and Lactosylceramide (2015) (0)
- Management of Aminotransferase Elevations Observed in a Phase 3 Study of Patients with Homozygous Familial Hypercholesterolemia Treated with Lomitapide (2013) (0)
- Abstract 5479: PPARgamma Agonist Redirects Macrophage Cholesterol from Fecal Excretion to Adipose Tissue Uptake in Mice (2008) (0)
- Tu-PL2:2 Molecular and pharmacologic regulation of reverse cholesterol transport (2006) (0)
- Abstract 15075: Genomic Risk Stratification Predicts All-Cause Mortality After Cardiac Catheterization (2018) (0)
- Translational Medicine in Atherosclerosis: From Human Genetics to New Biology to Novel Therapeutics (2012) (0)
- Abstract 75: Somatic Overexpression and Knockdown in Mice to Identify Causal Genes Underlying 26 Lipid-associated Loci (2013) (0)
- Author Correction: Longitudinal urinary biomarkers of immunological activation in covid-19 patients without clinically apparent kidney disease versus acute and chronic failure (2021) (0)
- Abstract 18399: Higher Plasma Cxcl12 Levels Are Causally Associated With Increased Risk of Coronary Heart Disease (2016) (0)
- Abstract 17619: Deep RNA-Sequencing Uncovers a Broad Species- And Cell-Specific lincRNA Repertoire That Modulates Human Macrophage Activation and Associates With Cardiometabolic Diseases (2017) (0)
- The affect of gravity on particle collection in inertial impactors (1990) (0)
- FENOFIBRIC AND NICOTINIC ACID PROGRESSIVELY SUPPRESS POSTPRANDIAL TRIGLYCERIDEMIA IN STATIN-TREATED PATIENTS WITH LOW HIGH-DENSITY LIPOPROTEIN CHOLESTEROL (2010) (0)
- SUN-593 Variants in Known Monogenic Causal Genes of Hypertriglyceridemia Are Not Major Contributors for Hypertriglyceridemia in Lipodystrophy Due to a LMNA Mutation (2020) (0)
- TBG . mLDLR and AAV 8 . TBG . hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia (2017) (0)
- CHOLESTEROL EFFLUX CAPACITY, HDL-PARTICLE NUMBER, AND INCIDENT CARDIOVASCULAR EVENTS: RESULTS FROM THE JUPITER TRIAL (2016) (0)
- Lack of MTTP Activity in P luripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress Graphical Abstract Highlights (2017) (0)
- The V122I mutation in hereditary transthyretin-mediated amyloidosis is significantly associated with an increased incidence of polyneuropathy (2020) (0)
- Performance of polygenic risk scores for cancer prediction in an academic biobank. (2020) (0)
- Whole genome sequencing reveals host factors underlying critical Covid-19 Accelerated Article Preview (2022) (0)
- LIPOPROTEIN(A) AND THE RISK FOR ATHEROSCLEROTIC CARDIOVASCULAR EVENTS AMONG ADULTS WITH CHRONIC KIDNEY DISEASE AND A HISTORY OF ATHEROSCLEROTIC CARDIOVASCULAR DISEASE (2022) (0)
- HDL, ABC Transporters and Cholesterol Efflux as Therapeutic Targets in Atherosclerosis (2012) (0)
- Rare loss of function variants in candidate genes and risk of colorectal cancer (2018) (0)
- Oral Administration of the Apolipoprotein A-1 Mimetic Peptide D-4f Promotes Cholesterol Efflux and Inhibits Atherosclerosis Progression in Chow-Fed Low Density Lipoprotein Receptor /apobec-1 Null Mice Even in the Absence of Endogenous Apolipoprotein A-1 (2006) (0)
- Methods for the treatment of disorders or diseases associated with hyperlipidemia and hypercholesterolemia, minimizing side effects (2005) (0)
- Genes Affecting Atherosclerosis in Mice Primarily Via Influencing Plasma Cholesterol Levels (2012) (0)
- Abstract 285: Association Of Patient Out-of-pocket Costs And Financial Assistance With Prescription Abandonment: The Case Of PCSK9 Inhibitors (2020) (0)
- Abstract 024: Association of APOL1 Risk Alleles with Coronary Heart Disease in Million Veteran Program (2018) (0)
- Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies (2023) (0)
- 157 Myeloid expression of trib1 regulates the polarisation state of tissue resident macrophages that has consequences on plasma lipid and metabolic homeostasis (2017) (0)
- Tangier disease ipsc-derived hepatocytes recapitulate HDL biogenesis defects and display elevated triglyceride secretion (2014) (0)
- Contrasting Views of Autism Spectrum Traits in Adults, Especially in Self-Reports vs. Informant-Reports for Women High in Autism Spectrum Traits (2022) (0)
- Endothelial lipase colon; a new member of the triglyceride lipase gene family (2000) (0)
- Abstract 18064: Lipid Reduction Measurements in a Veteran Population - Implications for Genetic Modeling in the Million Veteran Program (2016) (0)
- P4-041: The relationship of coronary calcification and cognitive performance in a multiethnic elderly cohort (2008) (0)
- Abstract 49: Adipose-Specific Knockout of Trib1 Reduces Plasma Lipids and Diet-Induced Insulin Resistance, and Increases Circulating Adiponectin (2017) (0)
- Mapping and characterization of structural variation in 17,795 human genomes (2020) (0)
- 25 ADIPOSITY AND PRO-ATHEROSCLEROTIC RESPONSES TO INNATE IMMUNE CHALLENGE IN HUMANS (2005) (0)
- In Memoriam: Julian B. Marsh (1926–2018) (2019) (0)
- Abstract 279: Using the Familial Hypercholesterolemia ICD-10 Code to Track Clinical Management of Patients at a Tertiary Academic Center (2019) (0)
- Abstract 16836: Ttc39b Deficiency Attenuates Atherosclerosis and Hepatic Steatosis Through Lxrα Dependent Manner (2016) (0)
- DSMC Simulations Investigating Chapman-Enskog Behavior in a Motionless Gas with Heat Flow (2003) (0)
- NOVEL CARDIOVASCULAR DISEASE (CVD) RISK FACTORS EL- EVATED IN YOUNG WOMEN WITH PCOS - POSSIBLE LINK BE- (2012) (0)
- Abstract 17262: Identification of a Rare Variant Near Neurexin 1 Associated with Coronary Artery Disease (2010) (0)
- The Majority of Outpatients With Severe Hypercholesterolemia at an Academic Tertiary Centre Have Not Been Screened for FH (2017) (0)
- IS022 Use of Gene Transfer as a Systemic Therapeutic Approach to Atherosclerosis (2000) (0)
- Abstract 20114: Impact of Genetic Testing on Cascade Screening for Familial Hypercholesterolemia - A Randomized Controlled Trial (2017) (0)
- Methods of treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia minimizing the adverse effects (2005) (0)
- Abstract 49: Knockout of ADAMTS7, a Novel Human CAD Locus, Reduces Atherosclerosis in Both LDLR and APOE Hyperlipidemic Mouse Models (2014) (0)
- Increased Cholesterol Efflux Capacity is Associated with Improved Survival in Heart Transplant Recipients (2014) (0)
- Role of Coronary Calcification Scanning in Risk Factor Assessment (2000) (0)
- Human knockouts and phenotypic analysis 1 in a cohort with a high rate of consanguinity 2 3 (2016) (0)
- Successful Nutritional Intervention for an Infant with Abetalipoproteinemia: A Novel Modular Formula (AbetaMF) (2021) (0)
- Clinical and biochemical characteristics are varied in subjects with ABCA1 mutations (2015) (0)
- Determination of thermal accommodation coefficients from heat transfer measurements between parallel plates. (2010) (0)
- Functional Biology of Genes at Novel Loci Associated With Coronary Artery Disease (2015) (0)
- Abstract 387: HDL Structure and Function in Individuals with Extreme High HDL-C Who Have Coronary Artery Disease Compared with Those Without CAD (2013) (0)
- Future Directions in HDL Research (2007) (0)
- Abstract 110: Deficiency of Apolipoprotein F Protects Mice from Western Diet-Induced Atherosclerosis on an LDL Receptor Knockout Background (2012) (0)
- Abstract P037: Progression Of Coronary Artery Calcification And Risk Of Clinical Events In Chronic Kidney Disease (2021) (0)
- Systemic Eicosanoid and Cytokine Response to Niacin: Implications in HPS2-THRIVE Trial and Beyond†∗ (2014) (0)
- Fatty acid and sterol induced lipotoxicity in yeast; modeling human pathophysiology? (2007) (0)
- Elimination of Platelet Factor 4 (PF4) from Platelets Reduces Atherosclerosis and Increases HDL Cholesterol in C57Bl/6 and ApoE−/− Mice. (2006) (0)
- Myeloid Tribbles 1 Regulates Experimental Atherosclerosis (2018) (0)
- Gain-of-Function Variants in Lipid Genes Enhance Biological Insight and Point Toward Therapeutic Opportunities. (2022) (0)
- Abstract 18128: Phenome-Wide Association Study of Familial Hypercholesterolemia Variants Among Multi-Ethnic Veterans (2017) (0)
- Abstract 16198: Ttc39b Deficiency Causes an Intestinal Lxr Activation Phenotype With Increased Expression Of Abca1 and HDL-Cholesterol Levels (2013) (0)
This paper list is powered by the following services:
Other Resources About Daniel Rader
What Schools Are Affiliated With Daniel Rader?
Daniel Rader is affiliated with the following schools:
- University of Washington
- University of Adelaide
- University of Cambridge
- University of Pennsylvania
- University of Leicester
- Jikei University School of Medicine
- Université de Montréal
- University of Delaware
- Lehigh University
- Tufts University
- Icahn School of Medicine at Mount Sinai
- University of California, Los Angeles
- Drexel University
- University of Toronto
- Columbia University
- University of Western Australia
- McGill University
- Massachusetts Institute of Technology
- Stanford University
