Daniela Salvemini
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Researcher ORCID 0000-0002-0612-4448
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(Suggest an Edit or Addition)Daniela Salvemini's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Nitric oxide activates cyclooxygenase enzymes. (1993) (1423)
- Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. (2001) (1130)
- A fluorometric assay for the measurement of nitrite in biological samples. (1993) (1043)
- Nitric oxide: a key mediator in the early and late phase of carrageenan‐induced rat paw inflammation (1996) (695)
- A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. (1999) (481)
- Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. (2003) (409)
- A Newly Identified Role for Superoxide in Inflammatory Pain (2004) (387)
- Modulation of Prostaglandin Biosynthesis by Nitric Oxide and Nitric Oxide Donors (2005) (336)
- Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. (1994) (318)
- Manganese superoxide dismutase, MnSOD and its mimics. (2012) (310)
- Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. (1989) (305)
- A role for superoxide in gentamicin-mediated nephropathy in rats. (2002) (279)
- Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. (1996) (273)
- Regulation of prostaglandin production by nitric oxide; an in vivo analysis (1995) (268)
- Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology. (1998) (260)
- On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies (2003) (244)
- Roles of reactive oxygen and nitrogen species in pain. (2011) (241)
- Sod mimetics are coming of age (2002) (241)
- Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. (1995) (235)
- Characterization of the Cytoprotective Action of Peroxynitrite Decomposition Catalysts* (1998) (229)
- Regulation of cyclooxygenase enzymes by nitric oxide (1997) (223)
- Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock. (2000) (197)
- Immediate release of a nitric oxide-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide (1990) (190)
- Oxidative stress in septic shock and disseminated intravascular coagulation. (2002) (188)
- Oxidative stress and neuroAIDS: triggers, modulators and novel antioxidants (2001) (185)
- Superoxide, peroxynitrite and oxidative/nitrative stress in inflammation. (2006) (179)
- Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators. (1996) (178)
- Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics (2015) (166)
- Synthesis of a nitric oxide-like factor from L-arginine by rat serosal mast cells: stimulation of guanylate cyclase and inhibition of platelet aggregation. (1990) (150)
- Roles of nitric oxide and superoxide in inflammation. (2003) (148)
- Superoxide anions enhance platelet adhesion and aggregation (1989) (147)
- Potential therapeutic effect of antioxidant therapy in shock and inflammation. (2004) (137)
- Targeting the Overproduction of Peroxynitrite for the Prevention and Reversal of Paclitaxel-Induced Neuropathic Pain (2012) (135)
- Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice. (2007) (134)
- Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403 (2001) (129)
- Protective effects of a superoxide dismutase mimetic and peroxynitrite decomposition catalysts in endotoxin‐induced intestinal damage (1999) (127)
- Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. (2015) (122)
- Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications. (2013) (121)
- Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion (2001) (120)
- Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. (2009) (120)
- Nitric Oxide: A Regulatory Mediator of Mast Cell Reactivity (1991) (119)
- The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1* (2014) (115)
- Molecular mechanisms involved in the reciprocal regulation of cyclooxygenase and nitric oxide synthase enzymes. (2007) (113)
- Interactions of nitric oxide with cyclooxygenase: in vitro, ex vivo, and in vivo studies. (1996) (109)
- Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy (2015) (105)
- Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine. (2003) (104)
- Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase (2013) (103)
- SUPEROXIDE POTENTIATES NF-κB ACTIVATION AND MODULATES ENDOTOXIN-INDUCED CYTOKINE PRODUCTION IN ALVEOLAR MACROPHAGES (2005) (99)
- A Role for Nitric Oxide-Mediated Peroxynitrite Formation in a Model of Endotoxin-Induced Shock (2006) (98)
- Blockade of Phencyclidine-Induced Cortical Apoptosis and Deficits in Prepulse Inhibition by M40403, a Superoxide Dismutase Mimetic (2003) (98)
- Superoxide: a key player in hypertension (2004) (97)
- Controlling murine and rat chronic pain through A3 adenosine receptor activation (2012) (97)
- Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development (2019) (95)
- Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain (2018) (93)
- Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo (2002) (91)
- Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic. (2001) (91)
- Nitric oxide from vascular smooth muscle cells: regulation of platelet reactivity and smooth muscle cell guanylate cyclase (1991) (90)
- Effect of M40403 treatment of diabetic rats on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve (2001) (90)
- Superoxide, superoxide dismutase and ischemic injury. (2002) (89)
- Counter-Regulation of Opioid Analgesia by Glial-Derived Bioactive Sphingolipids (2010) (88)
- Superoxide-mediated nitration of spinal manganese superoxide dismutase: a novel pathway in N-methyl-d-aspartate-mediated hyperalgesia (2004) (88)
- A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways (2014) (86)
- Cyclooxygenases 1 and 2 contribute to peroxynitrite‐mediated inflammatory pain hypersensitivity (2008) (86)
- Nitroxidative Signaling Mechanisms in Pathological Pain (2016) (85)
- Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide. (1992) (83)
- Modulation of platelet function by free radicals and free-radical scavengers. (1993) (81)
- The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic (2003) (80)
- Mitotoxicity in distal symmetrical sensory peripheral neuropathies (2014) (79)
- Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain (2010) (76)
- Spinal Ceramide Modulates the Development of Morphine Antinociceptive Tolerance via Peroxynitrite-Mediated Nitroxidative Stress and Neuroimmune Activation (2009) (75)
- Mitotoxicity in distal symmetrical sensory peripheral neuropathies (2014) (74)
- The role of superoxide and nuclear factor-kappaB signaling in N-methyl-D-aspartate-induced necrosis and apoptosis. (2002) (74)
- A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects (2003) (73)
- M40403, a superoxide dismutase mimetic, protects cochlear hair cells from gentamicin, but not cisplatin toxicity. (2003) (73)
- Manganese(III) complexes of bis(hydroxyphenyl)dipyrromethenes are potent orally active peroxynitrite scavengers. (2011) (71)
- Ceramide: a Key Signaling Molecule in a Guinea Pig Model of Allergic Asthmatic Response and Airway Inflammation (2008) (69)
- Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis. (2001) (69)
- Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion. (1999) (66)
- Engagement of the GABA to KCC2 Signaling Pathway Contributes to the Analgesic Effects of A3AR Agonists in Neuropathic Pain (2015) (66)
- Therapeutic manipulations of peroxynitrite. (1998) (65)
- Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels through astrocyte-dependent mechanisms (2018) (64)
- Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain (2019) (62)
- Effects of combination M40403 and dexamethasone therapy on joint disease in a rat model of collagen-induced arthritis. (2005) (62)
- Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic. (2005) (61)
- NCI Clinical Trials Planning Meeting for prevention and treatment of chemotherapy-induced peripheral neuropathy. (2019) (61)
- Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: Correlation with preserved circulating catecholamines* (2003) (60)
- Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins. (2009) (59)
- The use of oxyhaemoglobin to explore the events underlying inhibition of platelet aggregation induced by NO or NO‐donors (1990) (59)
- Mast cells as a source of superoxide anions and nitric oxide-like factor: relevance to histamine release. (1991) (58)
- Identification of A3 adenosine receptor agonists as novel non‐narcotic analgesics (2016) (55)
- Therapeutic targeting of the ceramide-to-sphingosine 1-phosphate pathway in pain. (2013) (55)
- Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance (2009) (54)
- NMDA-receptor activation and nitroxidative regulation of the glutamatergic pathway during nociceptive processing (2010) (53)
- Superoxide dismutase mimetics. (2002) (53)
- Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance (2010) (52)
- Nitric Oxide and Inflammation (2012) (52)
- Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)‐deficient mice (2003) (52)
- Expression of Inducible Nitric-oxide Synthase and Intracellular Protein Tyrosine Nitration in Vascular Smooth Muscle Cells (2003) (52)
- Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation (2017) (51)
- In Vivo Phenotypic Screening for Treating Chronic Neuropathic Pain: Modification of C2-Arylethynyl Group of Conformationally Constrained A3 Adenosine Receptor Agonists (2014) (50)
- Increased superoxide production causes coronary endothelial dysfunction and depressed oxygen consumption in the failing heart. (2005) (50)
- Diphenylene iodonium, an inhibitor of free radical formation, inhibits platelet aggregation. (1991) (49)
- The contribution of oxidative stress in apoptosis of human‐cultured astroglial cells induced by supernatants of HIV‐1‐infected macrophages (2002) (47)
- Bergamot Polyphenols Improve Dyslipidemia and Pathophysiological Features in a Mouse Model of Non-Alcoholic Fatty Liver Disease (2020) (47)
- Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways. (2009) (46)
- Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain. (2013) (46)
- The Protective Effect of Superoxide Dismutase Mimetic M40401 on Balloon Injury-Related Neointima Formation: Role of the Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 (2004) (46)
- Conversion of glyceryl trinitrate to nitric oxide in tolerant and non‐tolerant smooth muscle and endothelial cells (1993) (45)
- Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism (2013) (44)
- REDUCTION IN THE DEVELOPMENT OF CERULEIN-INDUCED ACUTE PANCREATITIS BY TREATMENT WITH M40401, A NEW SELECTIVE SUPEROXIDE DISMUTASE MIMETIC (2004) (44)
- Pharmacological manipulation of cyclo‐oxygenase‐2 in the inflamed hydronephrotic kidney (1996) (44)
- Paraquat-Induced Hair Cell Damage and Protection with the Superoxide Dismutase Mimetic M40403 (2004) (43)
- Treatment of chronic neuropathic pain: purine receptor modulation. (2020) (43)
- Oxaliplatin-induced blood brain barrier loosening: a new point of view on chemotherapy-induced neurotoxicity (2018) (42)
- Peroxynitrite: a strategic linchpin of opioid analgesic tolerance. (2009) (41)
- A catalyst of peroxynitrite decomposition inhibits murine experimental autoimmune encephalomyelitis (2000) (40)
- Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance (2013) (39)
- Efficient, large-scale synthesis and preclinical studies of MRS5698, a highly selective A3 adenosine receptor agonist that protects against chronic neuropathic pain (2015) (38)
- Cardioprotective activity of endogenous and exogenous nitric oxide on ischaemia reperfusion injury in isolated guinea pig hearts (1999) (38)
- GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents. (2020) (38)
- THE ROLE OF CYCLOOXYGENASE‐2 IN INFLAMMATION (1995) (38)
- Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion (2000) (38)
- Supraspinal Peroxynitrite Modulates Pain Signaling by Suppressing the Endogenous Opioid Pathway (2012) (37)
- Anti-superoxide and anti-peroxynitrite strategies in pain suppression. (2012) (37)
- Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins. (2011) (35)
- Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin (1992) (35)
- Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine (1991) (35)
- Targeting peroxynitrite driven nitroxidative stress with synzymes: A novel therapeutic approach in chronic pain management. (2010) (35)
- Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats (2011) (34)
- Retooling manganese(III) porphyrin-based peroxynitrite decomposition catalysts for selectivity and oral activity: a potential new strategy for treating chronic pain. (2011) (33)
- Intraplantar‐injected ceramide in rats induces hyperalgesia through an NF‐κB‐ and p38 kinase‐dependent cyclooxygenase 2/prostaglandin E2 pathway (2011) (32)
- Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance. (2005) (32)
- Activation of Sphingosine-1-Phosphate Receptor 1 in the Spinal Cord Produces Mechanohypersensitivity Through the Activation of Inflammasome and IL-1β Pathway. (2019) (32)
- Endothelial Nitric Oxide Synthase Is a Key Mediator of Interleukin-2-Induced Hypotension and Vascular Leak Syndrome (2011) (32)
- Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation. (2004) (31)
- Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia (2013) (30)
- Discovery of a better aspirin. (1995) (30)
- Nitric oxide and the cyclooxygenase pathway. (1995) (30)
- Peroxynitrite and opiate antinociceptive tolerance: a painful reality. (2009) (30)
- Sphingosine-1-phosphate acting via the S1P1 receptor is a downstream signaling pathway in ceramide-induced hyperalgesia (2011) (29)
- Human cells and networks of pain: Transforming pain target identification and therapeutic development (2021) (29)
- Inducible nitric oxide synthase and inflammation. (1998) (29)
- Antioxidant modulation of sirtuin 3 during acute inflammatory pain: The ROS control. (2020) (28)
- Adenosine A3 receptor activation inhibits pronociceptive N-type Ca2+ currents and cell excitability in dorsal root ganglion neurons. (2019) (28)
- The cystine/glutamate antiporter system xc− drives breast tumor cell glutamate release and cancer-induced bone pain (2016) (28)
- Nonpeptidyl mimetics of superoxide dismutase in clinical therapies for diseases (2000) (28)
- Cultured astrocytoma cells inhibit platelet aggregation by releasing a nitric oxide-like factor. (1990) (27)
- NITRIC OXIDE ACTIVATES THE CYCLOOXYGENASE PATHWAY IN INFLAMMATION (1995) (26)
- Lipopolysaccharide increases release of a nitric oxide-like factor from endothelial cells. (1989) (26)
- Accumulation of Porphyrin-based SOD Mimics in Mitochondria is Proportional to Their Lipophilicity: S. cerevisiae Study of ortho Mn(III) N-alkylpyridylporphyrins (2010) (24)
- Adenosine A3 agonists reverse neuropathic pain via T cell-mediated production of IL-10. (2021) (24)
- Sphingosine 1-Phosphate Receptor Subtype 1 as a Therapeutic Target for Brain Trauma. (2018) (24)
- Cultured astrocytoma cells generate a nitric oxide‐like factor from endogenous L‐arginine and glyceryl trinitrate: effect of E. coli lipopolysaccharide (1992) (24)
- Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury (2020) (24)
- INHIBITION OF CERAMIDE BIOSYNTHESIS AMELIORATES PATHOLOGICAL CONSEQUENCES OF SPINAL CORD INJURY (2009) (24)
- Chronic Morphine-Induced Changes in Signaling at the A3 Adenosine Receptor Contribute to Morphine-Induced Hyperalgesia, Tolerance, and Withdrawal (2020) (23)
- Cancer and orofacial pain (2016) (23)
- NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice (2013) (23)
- Lipophilicity of Mn(III) N-Alkylpyridylporphyrins Dominates Their Accumulation Within Mitochondria and Therefore in Vivo Efficacy: a Mouse Study (2011) (23)
- Anti-Inflammatory and Anti-Apoptotic Effects of Fumonisin B1, an Inhibitor of Ceramide Synthase, in a Rodent Model of Splanchnic Ischemia and Reperfusion Injury (2008) (22)
- Superoxide Dismutase Cooperates with Prostacyclin to Inhibit Platelet Aggregation: a Comparative Study in Washed Platelets and Platelet Rich Plasma (1991) (22)
- Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats. (1991) (21)
- Structural Probing of Off-Target G Protein-Coupled Receptor Activities within a Series of Adenosine/Adenine Congeners (2014) (21)
- Natural Antioxidant Control of Neuropathic Pain—Exploring the Role of Mitochondrial SIRT3 Pathway (2020) (21)
- Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance (2009) (20)
- Peripheral Adenosine A3 Receptor Activation Causes Regulated Hypothermia in Mice That Is Dependent on Central Histamine H1 Receptors (2016) (20)
- The effect of peroxynitrite decomposition catalyst MnTBAP on aldehyde dehydrogenase-2 nitration by organic nitrates: role in nitrate tolerance. (2014) (20)
- Severity of sepsis alters the effects of superoxide anion inhibition in a rat sepsis model. (2004) (19)
- Mini-Review: Mitochondrial dysfunction and chemotherapy-induced neuropathic pain (2021) (19)
- P2Y14 Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model. (2020) (19)
- Sexually dimorphic therapeutic response in bortezomib-induced neuropathic pain reveals altered pain physiology in female rodents. (2019) (19)
- Inhibition of human platelet aggregation by endothelium-derived relaxing factor, sodium nitroprusside or iloprost is potentiated by captopril and reduced thiols. (1991) (19)
- The metabolism of glyceryl trinitrate to nitric oxide in the macrophage cell line J774 and its induction by Escherichia coli lipopolysaccharide. (1992) (19)
- Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents. (2020) (18)
- Rigidified A3 Adenosine Receptor Agonists: 1-Deazaadenine Modification Maintains High in Vivo Efficacy. (2015) (18)
- Transient Receptor Potential Melastatin-3 (TRPM3) Mediates Nociceptive-Like Responses in Hydra vulgaris (2016) (18)
- Peroxynitrite decomposition catalyst prevents apoptotic cell death in a human astrocytoma cell line incubated with supernatants of HIV-infected macrophages (2002) (17)
- The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils (2003) (17)
- Exploration of Alternative Scaffolds for P2Y14 Receptor Antagonists Containing a Biaryl Core. (2020) (17)
- Structure-Based Design, Synthesis by Click Chemistry and in Vivo Activity of Highly Selective A3 Adenosine Receptor Agonists. (2015) (17)
- Acute visceral pain relief mediated by A3AR agonists in rats: involvement of N-type voltage-gated calcium channels. (2020) (16)
- FUMONISIN B1 REDUCES THE DEVELOPMENT OF MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN MICE (2009) (15)
- Studies on the importance of the proposed release of nitric oxide from platelets. (1991) (15)
- Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters. (2017) (14)
- Protective effects of M40401, a selective superoxide dismutase mimetic, on zymosan-induced nonseptic shock (2004) (13)
- New concepts in inflammation and therapy (1996) (13)
- Release of nitric oxide from glyceryl trinitrate by captopril but not enalaprilat: in vitro and in vivo studies (1993) (13)
- Targeting the Sphingosine-1-Phosphate Axis for Developing Non-narcotic Pain Therapeutics. (2020) (13)
- Exploring the Role of N6-Substituents in Potent Dual Acting 5'-C-Ethyltetrazolyladenosine Derivatives: Synthesis, Binding, Functional Assays, and Antinociceptive Effects in Mice ∇. (2017) (13)
- Design and in vivo activity of A3 adenosine receptor agonist prodrugs (2020) (12)
- Adenosine A3 receptor activation inhibits pro-nociceptive N-type Ca2+ currents and cell excitability in dorsal root ganglion neurons. (2019) (12)
- Uncovering the Mechanisms of Adenosine Receptor-Mediated Pain Control: Focus on the A3 Receptor Subtype (2021) (12)
- Rat mast cells inhibit platelet aggregation by releasing a nitric oxide-like factor: influence of histamine release. (1991) (11)
- Protective Effect of Antioxidants in Nitric Oxide/COX-2 Interaction during Inflammatory Pain: The Role of Nitration (2020) (11)
- Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists (2016) (11)
- The protective role of bergamot polyphenolic fraction on several animal models of pain (2016) (11)
- Inducible Nitric Oxide Synthase (iNOS) is Not Required for IL-2–induced Hypotension and Vascular Leak Syndrome in Mice (2008) (10)
- Targeting the A3 adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice (2022) (9)
- Structure-Activity Relationship of Heterocyclic P2Y14 Receptor Antagonists: Removal of the Zwitterionic Character with Piperidine Bioisosteres. (2021) (9)
- GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain (2020) (9)
- Vascular and anti‐platelet actions of 1,2‐ and 1,3‐glyceryl dinitrate (1993) (8)
- Chronic Pain: New Insights in Molecular and Cellular Mechanisms (2015) (8)
- DAGLα Inhibition as a Non-invasive and Translational Model of Episodic Headache (2021) (8)
- Highly selective A3 adenosine receptor agonists relieve chronic neuropathic pain (2017) (8)
- Extended N(6) substitution of rigid C2-arylethynyl nucleosides for exploring the role of extracellular loops in ligand recognition at the A3 adenosine receptor. (2014) (7)
- Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels via astrocyte-dependent mechanisms (2018) (7)
- Pure MnTBAP selectively scavenges peroxynitrite over superoxide: Comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two different models of oxidative stress injuries, SOD-specific E. coli model and carrageenan-induced pleurisy (2009) (7)
- Nitroblue tetrazolium inhibits oxidation of glyceryl trinitrate to nitric oxide in bovine aortic smooth muscle cells. (1994) (6)
- Past, present and future of cocaine- and amphetamine-regulated transcript peptide (2021) (6)
- The effect of relaxin on myocardial ischaemia-reperfusion injury and histamine release in vitro and in vivo (1996) (6)
- Behavioral / Cognitive Engagement of the GABA to KCC 2 Signaling Pathway Contributes to the Analgesic Effects of A 3 AR Agonists in Neuropathic Pain (2015) (5)
- DDD-028: a potent potential non-opioid, non-cannabinoid analgesic for neuropathic and inflammatory pain. (2014) (5)
- Nitroxidative stress in pain and opioid-induced adverse effects: therapeutic opportunities. (2021) (5)
- Targeting metabotropic adenosine receptors for neuropathic pain: Focus on A2A (2018) (5)
- Peroxynitrite decomposition catalyst blocks paclitaxel-induced neuropathic pain: microarray analysis of spinal cord gene expression (2011) (4)
- Adenosine Metabotropic Receptors in Chronic Pain Management (2021) (4)
- Nitric Oxide and Cyclooxygenases (1997) (4)
- Spinal A3 adenosine receptor activation acutely restores morphine antinociception in opioid tolerant male rats (2021) (4)
- The Protective Effect of Bergamot Polyphenolic Fraction (BPF) on Chemotherapy-Induced Neuropathic Pain (2021) (4)
- Effects of the SOD mimetic, M40403, on prostaglandin production in an in vivo model of ischemia and reperfusion in rat heart (2003) (4)
- Anti-Inflammatory and Anti-Apoptotic Effects of Fumonisin B 1 , an Inhibitor of Ceramide Synthase , in a Rodent Model of Splanchnic Ischemia and Reperfusion Injury (2008) (4)
- Targeting reactive nitroxidative species in preclinical models of migraine (2021) (3)
- Sphingosine-1-phosphate receptor 1 activation in the central nervous system drives cisplatin-induced cognitive impairment (2022) (3)
- The protective effect of bergamot derived flavonoid on the post-translational modulation of glutamate transmission: a new therapeutic approach for opioid tolerance management (2010) (3)
- Superoxide and chronic hypoxia-induced pulmonary hypertension in newborn piglets. (2005) (3)
- (336) A3 adenosine receptor agonists reverse established oxaliplatin-induced neuropathic pain through an IL-10 mediated mechanism of action in spinal cord (2014) (3)
- 297) Central adenosine A3 receptor (A3AR) activation reverses neuropathic pain (2014) (3)
- Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain (2021) (3)
- The Contribution of Nitroxidative Stress to Pathophysiological Pain and Opioid Analgesic Failure (2016) (2)
- (326) Supraspinal adenosine A3 receptor (A3AR) activation reverses chemotherapy-induced neuropathic pain through an IL-10 dependent mechanism (2015) (2)
- Evaluation of a Superoxide Dismutase Mimetic As an Adjunct to Interleukin 2 Based Cancer Therapy (2013) (2)
- The Adenosine-Receptor Axis in Chronic Pain (2018) (2)
- Supplemental Data Peripheral Adenosine A 3 Receptor Activation Causes Regulated Hypothermia in Mice that is Dependent on Central Histamine H 1 Receptors (2016) (2)
- Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents (2020) (2)
- Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y14R Antagonist. (2022) (2)
- The Deductive Reasoning Strategy Enables Biomedical Breakthroughs. (2021) (2)
- Investigating the Molecular Mechanisms Driving 7α,25‐dihydroxycholesterol‐GPR183‐Induced Hypersensitivity (2022) (2)
- Overcoming Stress, Hunger, and Pain: Cocaine- and Amphetamine-Regulated Transcript Peptide’s Promise (2021) (2)
- The Neurotoxin DSP-4 Induces Hyperalgesia in Rats that is Accompanied by Spinal Oxidative Stress and Cytokine Production (2018) (2)
- Role of manganese superoxide dismutase in cancer (2003) (2)
- Overcoming Stress, Hunger, and Pain,: CART Peptide's Promise. (2021) (2)
- Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo (2002) (1)
- (193) Contribution of IL-10 and T cells in beneficial effects exerted by A3 adenosine receptor agonists in blocking and reversing neuropathic pain (2017) (1)
- Correction: Ford et al., Engagement of the GABA to KCC2 Signaling Pathway Contributes to the Analgesic Effects of A3AR Agonists in Neuropathic Pain (2015) (1)
- Adenosine receptor subtype 3 (A3AR) agonists as novel analgesics in chronic neuropathic pain (2013) (1)
- Peroxynitrite Decomposition Catalysts as Adjuncts to Morphine for the Management of Chronic Pain States (2008) (1)
- Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury (2020) (1)
- Rigidi fi ed A 3 Adenosine Receptor Agonists : 1 ‐ Deazaadenine Modi fi cation Maintains High in Vivo E ffi cacy (2015) (1)
- A selective H4R antagonist prevents antigen-induced asthma-like reaction and airway inflammation in guinea pigs (2009) (1)
- Temporospatial expression of reactive nitroxidative species in supraspinal regions during the induction and maintenance of central sensitization (2010) (1)
- (341) Sphingosine 1-phosphate receptor 1 antagonism prevents morphine-induced antinociceptive tolerance and hyperalgesia (2014) (1)
- 187) Identification of spinal GPR160 as a novel protein promoting chronic neuropathic pain states (2017) (1)
- Superoxide derived peroxynitrite is essential to supraspinal descending facilitation of nociception (2011) (1)
- Development of GPR183 Antagonists to Treat Neuropathic Pain (2020) (1)
- Preclinical industrial research. (1996) (1)
- In response to the letter of Malfroy and Doctrow (2002) (1)
- Supraspinal descending facilitation of central sensitization depends on peroxynitrite regulation of opioid signaling (2011) (1)
- Role of Adenosine Kinase in Sphingosine-1-Phosphate Receptor 1-Induced Mechano-Hypersensitivities (2021) (1)
- Toll-like receptor-mediated neuroinflammation: relevance for cognitive dysfunctions. (2022) (1)
- Dexamethasone Inhibits the Inducible Bioconversion of Glyceryl Trinitrate to Nitric Oxide (2002) (1)
- Morphine-induced antinociceptive tolerance and hyperalgesia is mediated through sphingosine 1-phosphate receptor 1-dependent p38 and neuroinflammatory mechanisms (2013) (1)
- Cultured astrocytoma cells release a nitric oxide-like factor (1990) (0)
- Modulation of sirtuins during acute inflammatory pain: the role of ROS (2013) (0)
- Substituted pyridinio pentaazamakrozykle complex activity superoxide dismutase-with (2000) (0)
- Bergamot Polyphenols Improve Dyslipidemia and Pathophysiological Features in a Mouse Model of Non-Alcoholic Fatty Liver Disease (2020) (0)
- OP-JNCI190013 531..537 (2019) (0)
- P2Y14 receptor inhibition reverses mechanical sensitivity in a mouse model of chronic neuropathic pain (2022) (0)
- CD4 + T cells and IL-10 are required for the beneficial effects exerted by A 3 AR agonists in neuropathic pain (2018) (0)
- SUPEROXIDE DISMUTASE MIMETICS: NOVEL SMALL MOLECULES ANTI‐INFLAMMATORY AGENTS: 504 (2004) (0)
- The Phytochemical Synergistic Properties of Combination of Bergamot Polyphenolic Fraction and Cynara cardunculus Extract in Non-Alcoholic Fatty Liver Disease (2023) (0)
- Editorial Board (1991) (0)
- J774 Cells metabolise glyceryl trinitrate by an enzymic pathway which can be induced by E. colt lipopolysaccharide (1992) (0)
- Adenosine A3 Receptor (A3AR) Agonist for the Treatment of Bleomycin-Induced Lung Fibrosis in Mice (2022) (0)
- Regulation ofprostaglandin production bynitric oxide; an in (1995) (0)
- 1 Activation of GPR183 by 7α,25-dihydroxycholesterol induces behavioral hypersensitivity through MAPK and NF-κB (2022) (0)
- Adenosine A3 Receptor Expression and Function in Mitochondria (2016) (0)
- Substituted Pyridinopentaazamakrocyclokomplexe with superoxide dismutase (2000) (0)
- Mast cell derived relaxing factor and the effect of nitric oxide generators on mast cell histamine release (1990) (0)
- Synzymes of superoxide dismutase as anti-infianunatory agents (2001) (0)
- Center for Neurosciences Responsive to Jesuit Catholic Mission of Saint Louis University. (2021) (0)
- Peripheral Adenosine A 3 Receptor Activation Causes Regulated Hypothermia in Mice That Is Dependent on Central Histamine (2016) (0)
- Inhibition of chemotherapy‐induced neuropathic pain with S1P receptor modulators (2013) (0)
- Substituted pyridino-pentaazamakrocykluskomplekser with superoxide dismutaseaktivitet (2000) (0)
- Activation of GPR183 by 7α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through Mitogen-Activated Protein Kinase and Nuclear Factor-κB (2022) (0)
- A Role of NOD2 in CARTp‐mediated Mechano‐hypersensitivity (2022) (0)
- Protective effects of a superoxide dismutase mimetic, M40403 in acute and chronic inflammation (1999) (0)
- Nitric oxide regulation of eicosanoid production (2001) (0)
- Structure Activity Relationship and Biological Evaluation of Small Molecule Antagonists for G‐Protein Coupled Receptor Associated with Neuropathic Pain (2022) (0)
- Sphingosine-1-phosphate receptor subtype 1 activation in the central nervous system contributes to morphine withdrawal in rodents (2020) (0)
- Reply to “Role of manganese superoxide dismutase in cancer” (2003) (0)
- Contents Vol. 9, 2004 (2004) (0)
- (337) Bortezomib-induced neuropathic pain is blocked and reversed by blocking the S1P/S1PR1 axis (2014) (0)
- Targeting neuroinflammation in neuropathic pain and opioid use. (2023) (0)
- Sphingosine 1‐phosphate receptor 1 mediates morphine‐induced antinociceptive tolerance and hyperalgesia (2013) (0)
- Novel Non-Opioid Based Therapeutics for Chronic Neuropathic Pain. (2021) (0)
- (192) Targeting A3 adenosine receptor in HIV-1 gp120-induced neuropathic pain (2017) (0)
- (182) Sphingosine 1-phosphate receptor subtype 1: a neuroinflammatory rheostat of the spinal cord in the development of chronic pain (2017) (0)
- Subject Index Vol. 9, 2004 (2004) (0)
- BENEFICIAL EFFECT OF SUPEROXIDE DISMUTASE MIMETICS THE MULTIPLE ORGAN FAILURE INDUCED BY ZYMOSAN IN THE RAT.: 185 (2002) (0)
- Use of substituted pyridino pentaaazamykrozyklen complexes with superoxide dismutase activity (2000) (0)
- Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain (2010) (0)
- Targeting the A3 adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice (2022) (0)
- 42 SPHINGOSINE 1-PHOSPHATE: REGULATOR OF INFLAMMATION AND PAIN (2011) (0)
- (338) The role of peroxynitrite in peripheral nerve sensory axon mitotoxicity during chemotherapy-induced neuropathic pain (2014) (0)
- Searching for new strategies for the pharmacological treatment of chronic pain. (2010) (0)
- Methods of using peroxynitrite hajoamiskatalyyttien, pharmaceutical compositions for this purpose (1996) (0)
- Efficient, large-scale synthesis and preclinical studies of MRS5698, a highly selective A3 adenosine receptor agonist that protects against chronic neuropathic pain (2015) (0)
- (339) Spontaneous pain response in S-nitrosoglutathione reductase (GSNOR) deficient mice: the role of S-nitrosylation (2014) (0)
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What Schools Are Affiliated With Daniela Salvemini?
Daniela Salvemini is affiliated with the following schools:
