Daniele Piomelli
Italian-born American neuroscientist
Daniele Piomelli's AcademicInfluence.com Rankings

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Biology
Why Is Daniele Piomelli Influential?
(Suggest an Edit or Addition)According to Wikipedia, Daniele Piomelli is an Italian-born American scientist. He studied neuroscience in New York City, with James H. Schwartz and Eric R. Kandel at Columbia University College of Physicians and Surgeons and later with Paul Greengard at the Rockefeller University . Two of his mentors received in 2000 the Nobel Prize for their contributions to medicine. After working at the INSERM in Paris and at the Neurosciences Institute in La Jolla with Nobel Prize winner Gerald Edelman, he joined the University of California Irvine School of Medicine, where he is now Louise Turner Arnold Chair in Neurosciences and Professor of Anatomy and Neurobiology, Pharmacology and Biological Chemistry. He is also founding director of the department of Drug Discovery and Development at the Istituto Italiano di Tecnologia in Genova, Italy. He is also the editor of Cannabis and Cannabinoid Research and a board member of the non-profit International Association for Cannabinoid Medicines.
Daniele Piomelli's Published Works
Published Works
- The molecular logic of endocannabinoid signalling (2003) (1881)
- Role of endogenous cannabinoids in synaptic signaling. (2003) (1537)
- A second endogenous cannabinoid that modulates long-term potentiation (1997) (1480)
- Identification and Functional Characterization of Brainstem Cannabinoid CB2 Receptors (2005) (1434)
- Brain monoglyceride lipase participating in endocannabinoid inactivation (2002) (1301)
- Control of pain initiation by endogenous cannabinoids (1998) (1056)
- Modulation of anxiety through blockade of anandamide hydrolysis (2003) (1029)
- Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α (2003) (1020)
- Functional role of high-affinity anandamide transport, as revealed by selective inhibition. (1997) (810)
- Dopamine activation of endogenous cannabinoid signaling in dorsal striatum (1999) (796)
- Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia (2012) (795)
- The Nuclear Receptor Peroxisome Proliferator-Activated Receptor-α Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide (2005) (790)
- An endocannabinoid mechanism for stress-induced analgesia (2005) (706)
- An anorexic lipid mediator regulated by feeding (2001) (684)
- Correction for Gobbi et al., Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis (2005) (653)
- Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells (1987) (633)
- Molecular Composition of the Endocannabinoid System at Glutamatergic Synapses (2006) (508)
- A Peripheral Mechanism for CB1 Cannabinoid Receptor-Dependent Modulation of Feeding (2002) (502)
- The endocannabinoid system as a target for therapeutic drugs. (2000) (455)
- Cerebrospinal Anandamide Levels are Elevated in Acute Schizophrenia and are Inversely Correlated with Psychotic Symptoms (2004) (435)
- Elevated endogenous cannabinoids in schizophrenia. (1999) (431)
- Segregation of two endocannabinoid‐hydrolyzing enzymes into pre‐ and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala (2004) (428)
- Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3′-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation (2005) (423)
- Occurrence and Biosynthesis of Endogenous Cannabinoid Precursor,N-Arachidonoyl Phosphatidylethanolamine, in Rat Brain (1997) (404)
- PER2 controls lipid metabolism by direct regulation of PPARγ. (2010) (387)
- Pharmacological profile of the selective FAAH inhibitor KDS-4103 (URB597). (2006) (359)
- Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes (1995) (355)
- The lipid messenger OEA links dietary fat intake to satiety. (2008) (344)
- Anandamide Amidohydrolase Activity in Rat Brain Microsomes (1995) (341)
- A neuroscientist's guide to lipidomics (2007) (331)
- Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress (2007) (321)
- Biosynthesis of an Endogenous Cannabinoid Precursor in Neurons and its Control by Calcium and cAMP (1996) (317)
- Rapid Broad-Spectrum Analgesia through Activation of Peroxisome Proliferator-Activated Receptor-α (2006) (316)
- Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism (2010) (310)
- A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. (2002) (293)
- Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models (2006) (283)
- Elevated Brain Cannabinoid CB1 Receptor Availability in Posttraumatic Stress Disorder: A Positron Emission Tomography Study (2013) (280)
- Exercise activates the endocannabinoid system (2003) (277)
- Dopamine activation of the arachidonic acid cascade as a basis for D1D2 receptor synergism (1991) (275)
- Arachidonic Acid in Cell Signaling (1993) (273)
- Structural determinants for recognition and translocation by the anandamide transporter. (1999) (267)
- Oleoylethanolamide Stimulates Lipolysis by Activating the Nuclear Receptor Peroxisome Proliferator-activated Receptor α (PPAR-α)* (2004) (264)
- Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies. (2004) (263)
- Oleoylethanolamide, an endogenous PPAR-α agonist, lowers body weight and hyperlipidemia in obese rats (2005) (262)
- Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. (2001) (243)
- The search for the palmitoylethanolamide receptor. (2005) (236)
- The endocannabinoid system in brain reward processes (2008) (232)
- Reversal of Dopamine D2 Receptor Responses by an Anandamide Transport Inhibitor (2000) (231)
- Food Intake Regulates Oleoylethanolamide Formation and Degradation in the Proximal Small Intestine* (2007) (230)
- Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. (2001) (226)
- Carrier‐mediated transport and enzymatic hydrolysis of the endogenous cannabinoid 2‐arachidonylglycerol (2000) (226)
- N-Acylethanolamines in human reproductive fluids. (2002) (222)
- Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172. (2004) (220)
- Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: Impact of cannabis use (2007) (215)
- RNA Interference Suggests a Primary Role for Monoacylglycerol Lipase in the Degradation of the Endocannabinoid 2-Arachidonoylglycerol (2004) (214)
- Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation (2009) (211)
- Anxiolytic-Like Properties of the Anandamide Transport Inhibitor AM404 (2006) (210)
- Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome (2012) (205)
- Peripheral gating of pain signals by endogenous lipid mediators (2014) (205)
- Bidirectional control of airway responsiveness by endogenous cannabinoids (2000) (196)
- Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signalling. (1990) (191)
- Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease (2010) (190)
- Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus (2005) (188)
- The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3′-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice (2007) (185)
- Stimulation of Endocannabinoid Formation in Brain Slice Cultures through Activation of Group I Metabotropic Glutamate Receptors (2005) (184)
- Long-Term Plasticity of Endocannabinoid Signaling Induced by Developmental Febrile Seizures (2003) (184)
- Quantification of bioactive acylethanolamides in rat plasma by electrospray mass spectrometry. (2000) (180)
- Brain cannabinoids in chocolate (1996) (178)
- Endocannabinoid signal in the gut controls dietary fat intake (2011) (173)
- A catalytically silent FAAH-1 variant drives anandamide transport in neurons (2011) (172)
- A fatty gut feeling (2013) (170)
- Regulation of food intake by oleoylethanolamide (2005) (169)
- Design, synthesis, and structure-activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors. (2003) (166)
- Modulation of Meal Pattern in the Rat by the Anorexic Lipid Mediator Oleoylethanolamide (2003) (164)
- Endogenous Cannabinoid Signaling (1998) (163)
- Oleoylethanolamide stimulates lipolysis by activating the nuclear receptor peroxisome proliferator-activated receptor alpha (PPAR-alpha). (2004) (162)
- A Key Role for Diacylglycerol Lipase-α in Metabotropic Glutamate Receptor-Dependent Endocannabinoid Mobilization (2007) (162)
- Fatty Acid Amide Hydrolase Inhibition Heightens Anandamide Signaling Without Producing Reinforcing Effects in Primates (2008) (156)
- The endocannabinoid system: a drug discovery perspective. (2005) (152)
- Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa‐induced dyskinesias (2003) (150)
- Endocannabinoid signaling mediates oxytocin-driven social reward (2015) (148)
- TRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice (2017) (147)
- Anandamide elevation in cerebrospinal fluid in initial prodromal states of psychosis. (2009) (144)
- The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition (2008) (143)
- Eicosanoids in synaptic transmission. (1994) (143)
- Inhibition of Anandamide Hydrolysis by Cyclohexyl Carbamic Acid 3′-Carbamoyl-3-yl Ester (URB597) Reverses Abuse-Related Behavioral and Neurochemical Effects of Nicotine in Rats (2008) (139)
- Fat-induced satiety factor oleoylethanolamide enhances memory consolidation (2009) (138)
- Acute Intracerebroventricular Administration of Palmitoylethanolamide, an Endogenous Peroxisome Proliferator-Activated Receptor-α Agonist, Modulates Carrageenan-Induced Paw Edema in Mice (2007) (137)
- Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia. (2009) (133)
- Dopamine D2 Receptors Potentiate Arachidonate Release via Activation of Cytosolic, Arachidonate‐Specific Phospholipase A2 (1995) (133)
- Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. (2011) (131)
- Elevated circulating levels of anandamide after administration of the transport inhibitor, AM404. (2000) (131)
- Metabolites of arachidonic acid in the nervous system of Aplysia: possible mediators of synaptic modulation (1987) (131)
- Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity (2013) (126)
- Peripheral antinociceptive effects of inhibitors of monoacylglycerol lipase in a rat model of inflammatory pain (2011) (122)
- Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease. (2012) (117)
- Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease (2011) (116)
- Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat (2008) (115)
- Blockade of Nicotine Reward and Reinstatement by Activation of Alpha-Type Peroxisome Proliferator-Activated Receptors (2011) (114)
- The thrifty lipids: endocannabinoids and the neural control of energy conservation (2012) (113)
- The Fat-Induced Satiety Factor Oleoylethanolamide Suppresses Feeding through Central Release of Oxytocin (2010) (113)
- Release of Fatty Acid Amides in a Patient With Hemispheric Stroke: A Microdialysis Study (2002) (110)
- Genetic Deletion of Fatty Acid Amide Hydrolase Alters Emotional Behavior and Serotonergic Transmission in the Dorsal Raphe, Prefrontal Cortex, and Hippocampus (2010) (110)
- The Endogenous Cannabinoid Anandamide Produces δ-9-Tetrahydrocannabinol-Like Discriminative and Neurochemical Effects That Are Enhanced by Inhibition of Fatty Acid Amide Hydrolase but Not by Inhibition of Anandamide Transport (2007) (109)
- Lipidomic analysis of endocannabinoid metabolism in biological samples. (2009) (108)
- Targeted enhancement of oleoylethanolamide production in proximal small intestine induces across-meal satiety in rats. (2008) (104)
- Anandamide hydrolysis: a new target for anti-anxiety drugs? (2003) (104)
- Modulation of Neuropathic and Inflammatory Pain by the Endocannabinoid Transport Inhibitor AM404 [N-(4-Hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide] (2006) (102)
- Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study. (2003) (102)
- More surprises lying ahead. The endocannabinoids keep us guessing (2014) (102)
- Effects of Palmitoylethanolamide on Signaling Pathways Implicated in the Development of Spinal Cord Injury (2008) (101)
- URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. (2007) (101)
- Arachidonate 5‐Lipoxygenase and Its Activating Protein: Prominent Hippocampal Expression and Role in Somatostatin Signaling (1996) (101)
- Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice. (2009) (101)
- Regulation of brain anandamide by acute administration of ethanol. (2007) (100)
- Potentiation of anandamide hypotension by the transport inhibitor, AM404. (1997) (97)
- Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models (2013) (97)
- Oleoylethanolamide inhibits food intake in free-feeding rats after oral administration. (2004) (96)
- Isotope dilution GC/MS determination of anandamide and other fatty acylethanolamides in rat blood plasma (1998) (95)
- Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions. (2012) (92)
- Discovery of potent and reversible monoacylglycerol lipase inhibitors. (2009) (92)
- The Cannabis sativa Versus Cannabis indica Debate: An Interview with Ethan Russo, MD (2016) (91)
- Expression of a cloned rat histamine H2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation. (1992) (90)
- The endocannabinoid system as a target for the treatment of cannabis dependence (2009) (89)
- An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease (2012) (88)
- Pharmacological Characterization of Hydrolysis-Resistant Analogs of Oleoylethanolamide with Potent Anorexiant Properties (2006) (87)
- 2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism. (2012) (86)
- The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease (2011) (84)
- Interleukin-1 Enhances the ATP-Evoked Release of Arachidonic Acid from Mouse Astrocytes (1997) (83)
- The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs. (2009) (82)
- Intestinal lipid-derived signals that sense dietary fat. (2015) (82)
- Formation and action of 8-hydroxy-11,12-epoxy-5,9,14-icosatrienoic acid in Aplysia: a possible second messenger in neurons. (1989) (80)
- Decoding Functional Metabolomics with Docosahexaenoyl Ethanolamide (DHEA) Identifies Novel Bioactive Signals* (2011) (79)
- Effects of Fatty Acid Amide Hydrolase (FAAH) Inhibitors in Non-Human Primate Models of Nicotine Reward and Relapse (2015) (79)
- Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-α Initiates 2-Arachidonoylglycerol Formation and Endocannabinoid-Mediated Analgesia (2012) (78)
- Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines. (1995) (78)
- Proinflammatory Stimuli Control N-Acylphosphatidylethanolamine-Specific Phospholipase D Expression in Macrophages (2011) (78)
- The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat (2008) (77)
- A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity. (2014) (76)
- Inhibition of intestinal motility by anandamide, an endogenous cannabinoid. (1997) (76)
- Pharmacological Characterization of Memoquin, a Multi-Target Compound for the Treatment of Alzheimer's Disease (2013) (74)
- Endocannabinoids at the spinal level regulate, but do not mediate, nonopioid stress-induced analgesia (2006) (74)
- Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats (2010) (73)
- A critical cysteine residue in monoacylglycerol lipase is targeted by a new class of isothiazolinone‐based enzyme inhibitors (2009) (73)
- Role of the basolateral nucleus of the amygdala in endocannabinoid-mediated stress-induced analgesia (2006) (72)
- Endocannabinoid Signaling in the Control of Social Behavior (2017) (71)
- Inhibition of Ca2+/calmodulin-dependent protein kinase II by arachidonic acid and its metabolites. (1989) (71)
- Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition (2011) (70)
- Endocannabinoid signaling in the gut mediates preference for dietary unsaturated fats (2013) (70)
- Enhancement of Anandamide-Mediated Endocannabinoid Signaling Corrects Autism-Related Social Impairment (2016) (69)
- A Second Generation of Carbamate‐Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo (2009) (69)
- Conformational effects in enzyme catalysis: reaction via a high energy conformation in fatty acid amide hydrolase. (2007) (69)
- Structure of human N-acylphosphatidylethanolamine-hydrolyzing phospholipase D: regulation of fatty acid ethanolamide biosynthesis by bile acids. (2015) (68)
- Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain (2010) (68)
- Identification and characterization of carprofen as a multitarget fatty acid amide hydrolase/cyclooxygenase inhibitor. (2012) (68)
- The anandamide transport inhibitor AM404 reduces ethanol self‐administration (2007) (68)
- Enhancement of endocannabinoid signaling and the pharmacotherapy of depression. (2007) (67)
- A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation. (2015) (66)
- Distribution and function of monoacylglycerol lipase in the gastrointestinal tract. (2008) (66)
- FAAH deficiency promotes energy storage and enhances the motivation for food (2010) (66)
- Evaluation of the emotional phenotype and serotonergic neurotransmission of fatty acid amide hydrolase-deficient mice (2010) (66)
- Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates. (2008) (65)
- Brown Adipose Tissue Quantification in Human Neonates Using Water-Fat Separated MRI (2013) (65)
- Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain (2008) (65)
- The endocannabinoid system: a physiological perspective on its role in psychomotor control. (2000) (65)
- Leukotriene biosynthesis by canine and human coronary arteries. (1987) (64)
- Postprandial increase of oleoylethanolamide mobilization in small intestine of the Burmese python (Python molurus). (2006) (64)
- QM/MM modelling of oleamide hydrolysis in fatty acid amide hydrolase (FAAH) reveals a new mechanism of nucleophile activation. (2005) (63)
- Peroxisome Proliferator-Activated Receptor α Mediates Acute Effects of Palmitoylethanolamide on Sensory Neurons (2012) (63)
- Endocannabinoid transport tightly controls 2‐arachidonoyl glycerol actions in the hippocampus: effects of low temperature and the transport inhibitor AM404 (2004) (62)
- Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat (2006) (62)
- Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring (2006) (61)
- The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew) (2009) (61)
- Plasma lipidomics reveals potential prognostic signatures within a cohort of cystic fibrosis patients (2011) (61)
- The ligand that came from within. (2001) (61)
- A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations (2012) (60)
- An endocannabinoid signaling system modulates anxiety-like behavior in male Syrian hamsters (2008) (60)
- Determination of anandamide and other fatty acyl ethanolamides in human serum by electrospray tandem mass spectrometry. (2007) (59)
- Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? (2006) (59)
- Circadian Control of Fatty Acid Elongation by SIRT1 Protein-mediated Deacetylation of Acetyl-coenzyme A Synthetase 1* (2014) (59)
- Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. (2016) (58)
- Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling. (2008) (58)
- Rapid pain modulation with nuclear receptor ligands (2009) (57)
- Multitarget fatty acid amide hydrolase/cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti‐inflammatory drug‐dependent gastrointestinal damage (2015) (56)
- Advances in the discovery of N-acylethanolamine acid amidase inhibitors. (2014) (56)
- Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities (2017) (56)
- Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation (2016) (55)
- Synthesis and structure-activity relationships of N-(2-oxo-3-oxetanyl)amides as N-acylethanolamine-hydrolyzing acid amidase inhibitors. (2010) (54)
- The identification of peroxisome proliferator‐activated receptor alpha‐independent effects of oleoylethanolamide on intestinal transit in mice (2009) (53)
- Bidirectional control of phospholipase A2 activity by Ca2+/calmodulin-dependent protein kinase II, cAMP-dependent protein kinase, and casein kinase II. (1991) (53)
- Role of endocannabinoids and their analogues in obesity and eating disorders (2011) (52)
- Effects of peripheral FAAH blockade on NTG-induced hyperalgesia—evaluation of URB937 in an animal model of migraine (2015) (52)
- A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation (2016) (52)
- Formation and biological activity of 12-ketoeicosatetraenoic acid in the nervous system of Aplysia. (1988) (52)
- A Lipid Gate for the Peripheral Control of Pain (2014) (52)
- A Novel Lipidomic Strategy Reveals Plasma Phospholipid Signatures Associated with Respiratory Disease Severity in Cystic Fibrosis Patients (2009) (51)
- Feeding-induced oleoylethanolamide mobilization is disrupted in the gut of diet-induced obese rodents. (2015) (51)
- Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C (1993) (51)
- Role of the endogenous cannabinoid system as a modulator of dopamine transmission: Implications for Parkinson’s disease and schizophrenia (2009) (50)
- Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-alpha receptor agonist GW7647. (2007) (49)
- Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy (2008) (48)
- A binding site for nonsteroidal anti-inflammatory drugs in fatty acid amide hydrolase. (2013) (48)
- Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity (2013) (48)
- Acid Ceramidase in Melanoma (2015) (48)
- Cannabinoid Type 1 Receptor Availability in the Amygdala Mediates Threat Processing in Trauma Survivors (2014) (47)
- Endocannabinoid System and Migraine Pain: An Update (2018) (47)
- N-(2-oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships. (2012) (47)
- Role of the satiety factor oleoylethanolamide in alcoholism (2016) (47)
- Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. (2015) (46)
- A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy. (2010) (46)
- Sympathetic Activity Controls Fat-Induced Oleoylethanolamide Signaling in Small Intestine (2011) (46)
- Anandamide transport inhibition by the vanilloid agonist olvanil. (1999) (46)
- Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid (2009) (45)
- Tandem mass spectrometric data-FAAH inhibitory activity relationships of some carbamic acid O-aryl esters. (2004) (44)
- Oleylethanolamide activates Ras-Erk pathway and improves myocardial function in doxorubicin-induced heart failure. (2006) (44)
- Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells (2017) (44)
- An Important Role for N-Acylethanolamine Acid Amidase in the Complete Freund’s Adjuvant Rat Model of Arthritis (2016) (42)
- Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure. (2011) (42)
- Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways. (2015) (41)
- Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors. (2013) (41)
- Neurophysiology of space travel: energetic solar particles cause cell type-specific plasticity of neurotransmission (2016) (41)
- Monoglyceride lipase: Structure and inhibitors. (2016) (41)
- Atypical Endocannabinoid Signaling Initiates a New Form of Memory-Related Plasticity at a Cortical Input to Hippocampus (2018) (40)
- Structure–Property Relationships of a Class of Carbamate‐Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability (2009) (40)
- Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs. (2010) (40)
- Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR). (2013) (40)
- The endogenous cannabinoid system and the treatment of marijuana dependence (2004) (39)
- N-acylethanolamine Acid Amidase (NAAA): Structure, Functions and Inhibition. (2020) (39)
- The Antinociceptive Effects of Local Injections of Propofol in Rats Are Mediated in Part by Cannabinoid CB1 and CB2 Receptors (2007) (39)
- Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis. (2016) (39)
- Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas. (2011) (38)
- Inhibition of anandamide hydrolysis in rat brain tissue by (E)‐6‐(bromomethylene) tetrahydro‐3‐(1‐naphthalenyl)‐2H‐pyran‐2‐one (1997) (38)
- Rapid evaluation of 25 key sphingolipids and phosphosphingolipids in human plasma by LC-MS/MS (2015) (38)
- Ten years of Nature Reviews Neuroscience: insights from the highly cited (2010) (37)
- CD36 gene deletion decreases oleoylethanolamide levels in small intestine of free-feeding mice. (2010) (37)
- Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats (2016) (37)
- Attenuation of spontaneous opiate withdrawal in mice by the anandamide transport inhibitor AM404. (2002) (37)
- A role for the endogenous cannabinoid system in the peripheral control of pain initiation. (2000) (37)
- An endocannabinoid signal associated with desire for alcohol is suppressed in recently abstinent alcoholics (2009) (37)
- Sample preparation and orthogonal chromatography for broad polarity range plasma metabolomics: application to human subjects with neurodegenerative dementia. (2014) (37)
- Therapeutic opportunities through modulation of the endocannabinoid system (2005) (36)
- Cold Exposure Stimulates Synthesis of the Bioactive Lipid Oleoylethanolamide in Rat Adipose Tissue* (2006) (36)
- The challenge of brain lipidomics. (2005) (36)
- Barium Evokes Glutamate Release from Rat Brain Synaptosomes by Membrane Depolarization: Involvement of K+, Na+, and Ca2+ Channels (1993) (36)
- Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice (2015) (36)
- β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine. (2012) (36)
- Towards a whole-body systems [multi-organ] lipidomics in Alzheimer's disease. (2011) (35)
- The N-Acylethanolamine Acid Amidase Inhibitor ARN077 Suppresses Inflammation and Pruritus in a Mouse Model of Allergic Dermatitis. (2017) (35)
- Methamphetamine Accelerates Cellular Senescence through Stimulation of De Novo Ceramide Biosynthesis (2015) (35)
- Membrane localization of N-acylphosphatidylethanolamine in central neurons: studies with exogenous phospholipases. (1996) (35)
- Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus (2007) (34)
- Lipidomic analysis of biological samples by liquid chromatography coupled to mass spectrometry. (2009) (34)
- Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase. (2007) (34)
- Decreased body weight and hepatic steatosis with altered fatty acid ethanolamide metabolism in aged L-Fabp −/− mice[S] (2012) (34)
- Bile Acid Recognition by NAPE-PLD. (2016) (32)
- Quantum mechanics/molecular mechanics modeling of fatty acid amide hydrolase reactivation distinguishes substrate from irreversible covalent inhibitors. (2013) (32)
- Characterization of the fatty-acid amide hydrolase inhibitor URB 597 : Effects on anandamide and oleoylethanolamide deactivation (2004) (32)
- Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons. (2015) (32)
- Participation of Prostaglandin E2 in Dopamine D2 Receptor‐Dependent Potentiation of Arachidonic Acid Release (1992) (31)
- Mast Cell-Derived Histamine Regulates Liver Ketogenesis via Oleoylethanolamide Signaling. (2019) (31)
- Synthesis, Structure–Activity, and Structure–Stability Relationships of 2‐Substituted‐N‐(4‐oxo‐3‐oxetanyl) N‐Acylethanolamine Acid Amidase (NAAA) Inhibitors (2014) (30)
- Pharmacokinetic, behavioral, and brain activity effects of Δ9-tetrahydrocannabinol in adolescent male and female rats (2020) (30)
- Ion mobility mass spectrometry enhances low-abundance species detection in untargeted lipidomics (2016) (30)
- Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male Mice (2020) (30)
- Elevated plasma ceramide levels in post-menopausal women: a cross-sectional study (2018) (30)
- Treating a novel plasticity defect rescues episodic memory in Fragile X model mice (2017) (30)
- Molecular mechanism of activation of the immunoregulatory amidase NAAA (2018) (29)
- A role for the endocannabinoid 2-arachidonoyl-sn-glycerol for social and high-fat food reward in male mice (2016) (29)
- Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety (2018) (29)
- Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies. (2016) (29)
- Endogenous N-acyl taurines regulate skin wound healing (2016) (29)
- Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats (2016) (29)
- Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats (2017) (29)
- Associations of Fatty Acids in Cerebrospinal Fluid with Peripheral Glucose Concentrations and Energy Metabolism (2012) (28)
- Synthesis and structure-activity relationships of a series of pyrrole cannabinoid receptor agonists. (2003) (28)
- Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat[S] (2016) (27)
- FAAH inhibition as a preventive treatment for migraine: A pre-clinical study (2020) (27)
- The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues. (2006) (26)
- Cannabinoid CB2 receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear (2020) (26)
- Synergistic effects of galantamine and memantine in attenuating scopolamine-induced amnesia in mice. (2012) (25)
- Erratum: Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis (Proceedings of the National Academy of Sciences of the United States of America (December 20, 2005) 102, 51 (18620-18625) DOI: 10.1073/pnas.0509591102) (2006) (25)
- Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase** (2014) (25)
- Synthesis and characterization of the first inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD). (2017) (25)
- Fluorine nuclear magnetic resonance-based assay in living mammalian cells. (2016) (25)
- Acid Ceramidase in Melanoma EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION (2016) (25)
- Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus. (2017) (25)
- The ABC membrane transporter ABCG2 prevents access of FAAH inhibitor URB937 to the central nervous system. (2011) (24)
- Understanding the role of carbamate reactivity in fatty acid amide hydrolase inhibition by QM/MM mechanistic modelling. (2011) (24)
- 3‐Aminoazetidin‐2‐one Derivatives as N‐Acylethanolamine Acid Amidase (NAAA) Inhibitors Suitable for Systemic Administration (2014) (24)
- Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies. (2015) (24)
- Potent α-amino-β-lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure-activity relationship (SAR) studies. (2016) (24)
- Increased Renal 2-Arachidonoylglycerol Level Is Associated with Improved Renal Function in a Mouse Model of Acute Kidney Injury (2016) (24)
- Wagging the Tail: Essential Role of Substrate Flexibility in FAAH Catalysis. (2013) (23)
- Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood‐placenta barrier (2012) (23)
- Identification of a bioactive impurity in a commercial sample of 6-methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754). (2007) (23)
- A role for endocannabinoids in viral-induced dyskinetic and convulsive phenomena (2005) (23)
- A phospholipase A2-stimulating protein regulated by protein kinase C in Aplysia neurons. (1991) (22)
- Effects of Acute Stress on Cardiac Endocannabinoids, Lipogenesis, and Inflammation in Rats (2014) (22)
- Characterization of the peripheral FAAH inhibitor, URB937, in animal models of acute and chronic migraine (2020) (22)
- Activity-Based Probe for N-Acylethanolamine Acid Amidase. (2015) (22)
- Antipsychotic Effects of Cannabidiol (2009) (21)
- Applying a multitarget rational drug design strategy: the first set of modulators with potent and balanced activity toward dopamine D3 receptor and fatty acid amide hydrolase. (2014) (21)
- Diacylglycerol Lipase-α and -β Control Neurite Outgrowth in Neuro-2a Cells through Distinct Molecular Mechanisms (2011) (21)
- Synthesis and structure-activity relationship studies of O-biphenyl-3-yl carbamates as peripherally restricted fatty acid amide hydrolase inhibitors. (2013) (21)
- Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic–ischemic brain injury in rats (2012) (20)
- Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability. (2011) (20)
- Familial abnormalities of endocannabinoid signaling in schizophrenia (2019) (20)
- Responses to stress: from the periphery to the brain. (2009) (20)
- Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain (2012) (20)
- Divergence in vascular actions of prostacyclin during vertebrate evolution (1985) (19)
- Divergence in vascular actions of prostacyclin during vertebrate evolution (1985) (19)
- Remote memories are enhanced by COMT activity through dysregulation of the endocannabinoid system in the prefrontal cortex (2018) (19)
- Endocannabinoid-Based Therapies. (2021) (19)
- The role of arachidonic acid metabolites in signal transduction in an identified neural network mediating presynaptic inhibition in Aplysia. (1988) (19)
- Erratum: Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus (Nature Neuroscience (2005) 8, (1139-1141)) (2007) (18)
- Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report. (2008) (18)
- THC: moderation during implantation (2004) (18)
- Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit. (2018) (18)
- Dysfunctional oleoylethanolamide signaling in a mouse model of Prader‐Willi syndrome (2017) (17)
- Metabolism of arachidonic acid in nervous system of marine mollusk Aplysia californica. (1991) (17)
- Dopamine D2 receptor signaling via the arachidonic acid cascade: modulation by cAMP-dependent protein kinase A and prostaglandin E2. (1993) (17)
- Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice (2015) (16)
- Targeted lipidomics as a tool to investigate endocannabinoid function. (2009) (16)
- Development of Fragment‐Based n‐FABS NMR Screening Applied to the Membrane Enzyme FAAH (2013) (16)
- Role of oleoylethanolamide as a feeding regulator in goldfish (2014) (16)
- Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease. (2014) (16)
- Fast and Sensitive Quantification of Δ9-Tetrahydrocannabinol and Its Main Oxidative Metabolites by Liquid Chromatography/Tandem Mass Spectrometry (2019) (15)
- Medicinal plants for the treatment of urogenital tract pathologies according to Dioscorides' De Materia Medica. (1997) (15)
- Peripheral Endocannabinoids Associated With Energy Expenditure in Native Americans of Southwestern Heritage (2018) (15)
- A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation (2016) (15)
- Pitfalls and solutions in assaying anandamide transport in cells[S] (2010) (15)
- Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin (2021) (14)
- Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL (2016) (14)
- Pharmacokinetic and pharmacodynamic properties of aerosolized (“vaped”) THC in adolescent male and female rats (2021) (14)
- Suppression of acute and anticipatory nausea by peripherally restricted fatty acid amide hydrolase inhibitor in animal models: role of PPARα and CB1 receptors (2017) (14)
- Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N-acylethanolamine acid amidase (NAAA) inhibitors. (2014) (14)
- Progress in the development of β-lactams as N-Acylethanolamine Acid Amidase (NAAA) inhibitors: Synthesis and SAR study of new, potent N-O-substituted derivatives. (2017) (13)
- Inhibition of monoacylglycerol lipase: Another signalling pathway for potential therapeutic targets in migraine? (2018) (13)
- Cannabinoid activity curtails cocaine craving (2001) (13)
- Endogenous cannabinoid signaling and psychomotor disorders. (2000) (13)
- Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware (2017) (13)
- New lipidomic approaches in cystic fibrosis. (2011) (12)
- Dietary and Behavioral Interventions Protect against Age Related Activation of Caspase Cascades in the Canine Brain (2011) (12)
- A study in Renaissance psychotropic plant ointments. (1994) (12)
- Erratum: Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs (Journal of Alzheimer's Disease (2010) 22:1 (135-150) DOI: 10.3233/JAD-2010-100639) (2011) (12)
- Different distribution of serotonin in an elasmobranch (Scyliorhinus stellaris) and in a teleost (Conger conger) fish. (1983) (12)
- Patch clamp-assisted single neuron lipidomics (2017) (12)
- Inhibition of anandamide hydrolysis by URB597 reverses abuse-related behavioral and neurochemical effects of nicotine in rats (2009) (11)
- Fluorine NMR‐Based Screening on Cell Membrane Extracts (2014) (11)
- Inhibition of fatty acid amide hydrolase in the CNS prevents and reverses morphine tolerance in male and female mice (2020) (11)
- O‐(Triazolyl)methyl Carbamates as a Novel and Potent Class of Fatty Acid Amide Hydrolase (FAAH) Inhibitors (2015) (11)
- Anandamide transport inhibition by ARN272 attenuates nausea‐induced behaviour in rats, and vomiting in shrews (Suncus murinus) (2013) (11)
- N-Acylethanolamine Acid Amidase (NAAA): Mechanism of Palmitoylethanolamide Hydrolysis Revealed by Mechanistic Simulations (2020) (11)
- Bedside to Bench: The element of surprise (2008) (11)
- A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration (2019) (11)
- Ablation of Acid Ceramidase Impairs Autophagy and Mitochondria Activity in Melanoma Cells (2021) (10)
- Selective cannabinoid-1 receptor blockade benefits fatty acid and triglyceride metabolism significantly in weight-stable nonhuman primates. (2012) (10)
- Targeted lipidomics: signaling lipids and drugs of abuse. (2005) (10)
- FAAH deficiency promotes energy storage and enhances the motivation for food (2012) (10)
- Biologically Active Metabolites of the 12‐Lipoxygenase Pathway Are Formed by Aplysia Nervous Tissue (1989) (10)
- 12‐Keto‐Eicosatetraenoic Acid A Biologically Active Eicosanoid in the Nervous System of Aplysia (1989) (10)
- Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition. (2016) (9)
- The Synthetic Cannabinoid URB447 Reduces Brain Injury and the Associated White Matter Demyelination after Hypoxia-Ischemia in Neonatal Rats (2020) (9)
- Erratum: Brain monoglyceride lipase participating in endocannabinoid inactivation (Proceedings of the National Academy of Sciences of the United States of America (August 6, 2002) 99:16 (10819-10824)) (2002) (9)
- N-Acylethanolamine Acid Amidase contributes to disease progression in a mouse model of multiple sclerosis. (2020) (9)
- Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain. (2014) (9)
- Dual cyclooxygenase–fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site (2018) (9)
- A simple and accurate protocol for absolute polar metabolite quantification in cell cultures using quantitative nuclear magnetic resonance. (2016) (9)
- Serum Endocannabinoid Levels in Patients With End-Stage Renal Disease (2019) (9)
- The cyclo-oxygenase pathway in the avascular heart of the frog, Rana esculenta L. (1984) (9)
- The endocannabinoid system in the adipose organ (2021) (9)
- NAAA-regulated lipid signaling governs the transition from acute to chronic pain (2021) (9)
- Circulating Endocannabinoids and Mortality in Hemodialysis Patients (2020) (8)
- Chapter 4.5 The endocannabinoid system and anxiety responses (2008) (8)
- Pot of gold for glioma therapy (2000) (8)
- Title Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM 1172 (2004) (8)
- Endogenous Lipids that Activate Cannabinoid Receptors (1997) (8)
- Cannabis and the Opioid Crisis (2018) (8)
- A thickening network of lipids (2012) (7)
- Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood (2022) (7)
- Palmitoylethanolamide and hemp oil extract exert synergistic anti-nociceptive effects in mouse models of acute and chronic pain. (2021) (7)
- Exposure to the cannabinoid agonist WIN 55, 212-2 in adolescent rats causes sleep alterations that persist until adulthood. (2020) (7)
- Comparative Pharmacokinetics of Δ9-Tetrahydrocannabinol in Adolescent and Adult Male and Female Rats. (2022) (7)
- Cannabinoids and Endocannabinoids (2015) (7)
- Pharmacokinetics, pharmacodynamics and safety studies on URB937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats (2019) (7)
- Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamate FAAH inhibitors. (2007) (7)
- Neurobiology of Marijuana (2014) (7)
- Legal or Illegal, Cannabis Is Still Addictive (2016) (7)
- Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence (2019) (7)
- Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy (2020) (6)
- Waiting for the Entourage. (2019) (6)
- Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign. (2020) (6)
- Development of a Multigram Synthesis of URB937, a Peripherally Restricted FAAH Inhibitor (2013) (6)
- The endogenous cannabinoid anandamide produces THC-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase ( FAAH ) but not by inhibition of anandamide transport (2007) (6)
- Ceramide contributes to pathogenesis and may be targeted for therapy in VCP inclusion body myopathy. (2020) (6)
- Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteines. (2019) (5)
- N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats (2020) (5)
- Moving beyond "good fat, bad fat": the complex roles of dietary lipids in cellular function and health: session abstracts. (2012) (5)
- A mighty (ochondrial) fight? (2014) (5)
- Endocannabinoid Anandamide Mediates the Effect of Skeletal Muscle Sphingomyelins on Human Energy Expenditure (2018) (5)
- Title Anxiolytic-like properties of the anandamide transport inhibitor AM 404 Permalink (2006) (5)
- Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis (2021) (5)
- Pleiotropic Effect of Human ApoE4 on Cerebral Ceramide and Saturated Fatty Acid Levels. (2017) (5)
- Novel activity-based probes for N-acylethanolamine acid amidase. (2017) (5)
- Pyrazole-Based Acid Ceramidase Inhibitors: Design, Synthesis, and Structure–Activity Relationships (2016) (4)
- Cannabinoids and Cancer Chemotherapy-Associated Adverse Effects. (2021) (4)
- The FAAH inhibitor PF‐04457845 has THC‐like rewarding and reinstatement effects in squirrel monkeys and increases dopamine levels in the nucleus accumbens shell in rats (838.6) (2014) (4)
- Distribution and function of monoacylglycerol lipase in the gastrointestinal tract (vol 295, pg G1255, 2008) (2011) (4)
- Diurnal Profiles of N-Acylethanolamines in Goldfish Brain and Gastrointestinal Tract: Possible Role of Feeding (2019) (4)
- The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity. (2009) (4)
- Peripheral gating of pain signals by endogenous analgesic lipids (2014) (4)
- Fatty acid amide hydrolase inhibition in the central nervous system prevents and reverses morphine tolerance in male and female mice. (2020) (4)
- Short communication Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-α receptor agonist GW7647 (2007) (3)
- Le cannabis: De la drogue au médicament (1999) (3)
- Proinflammatory stimuli control NAPE-PLD expression in macrophages (2011) (3)
- Endogenous lipids that activate cannabinoid receptors. Formation and inactivation. (1997) (3)
- Leukotrienes in teleost fish gills (1985) (3)
- Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase (2021) (3)
- Specific Skeletal Muscle Sphingolipid Compounds in Energy Expenditure Regulation and Weight Gain in Native Americans of Southwestern Heritage (2017) (3)
- Pancreatic Pain—Knowledge Gaps and Research Opportunities in Children and Adults (2021) (3)
- A Guide to the National Academy of Science Report on Cannabis: An Exclusive Discussion with Panel Members (2017) (3)
- Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase. (2016) (3)
- Cannabinoid-Based Drugs: Potential Applications in Addiction and Other Mental Disorders (2015) (3)
- W1350 the Distribution and Function of Monoacylglycerol Lipase, An Endogenous Cannabinoid Inactivation Enzyme, in the Enteric Nervous System (2008) (2)
- Regulatory Barriers to Research on Cannabis and Cannabinoids: A Proposed Path Forward. (2019) (2)
- Absolute nutrient concentration measurements in cell culture media: 1H q-NMR spectra and data to compare the efficiency of pH-controlled protein precipitation versus CPMG or post-processing filtering approaches (2016) (2)
- Persistent Exposure to Δ9-Tetrahydrocannabinol during Adolescence Does Not Affect Nociceptive Responding in Adult Mice (2021) (2)
- 39th Annual European Brain and Behaviour Society Abstracts (2007) (2)
- Persistent sexually dimorphic effects of adolescent THC exposure on hippocampal synaptic plasticity and episodic memory in rodents (2021) (2)
- Title The antinociceptive effects of local injections of propofol in rats are mediated in part by cannabinoid CB 1 and CB 2 receptors (2007) (2)
- Inside Cover: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. Int. Ed. 2/2015) (2015) (2)
- Erratum: The endocannabinoid system in brain reward processes (British Journal of Pharmacology (2008) 154:2 (369-383)) (2011) (2)
- The fat-induced satiety factor OEA suppresses feeding through central release of oxytocin (2010) (2)
- Erratum: Peripheral gating of pain signals by endogenous lipid mediators (2014) (2)
- Before Metabolism: Arachidonate as an Intracellular Second Messenger (1996) (2)
- Diet-Induced Obesity Disrupts Histamine-Dependent Oleoylethanolamide Signaling in the Mouse Liver (2022) (2)
- Effects of URB937 on an animal model of migraine pain (2013) (2)
- Central and peripheral endocannabinoids and cognate acylethanolamides in humans: Association with race, adiposity, and energy expenditure (Journal of Clinical Endocrinology and Metabolism (2011) 96, (787-791)) (2011) (2)
- Potent a -amino- b -lactam carbamic acid ester as NAAA inhibitors. Synthesis and structure e activity relationship (SAR) studies European (2)
- Lipidomics of Alzheimer’s disease: a liver peroxisomal dysfunction in the metabolism of omega-3 fatty acids (2011) (2)
- Reduced DMPC and PMPC in lung surfactant promote SARS-CoV-2 infection in obesity (2022) (1)
- Lack of abuse liability of the FAAH inhibitor URB597 in squirrel monkeys (2007) (1)
- A KEY ROLE FOR THE ENDOCANNABINOID SYSTEM IN INFLAMMATORY BOWEL DISEASE (2008) (1)
- Adipose Tissue Quantification in Human Neonates Using Water-Fat Separated MRI Permalink (2013) (1)
- Lipids | The Endocannabinoid System (2020) (1)
- Vasoconstrictory effects of adrenalin on the perfused head of the eel (Anguilla anguilla L.). (1983) (1)
- Reply: cannabinoid paths to anti-diarrheal drugs (2000) (1)
- The case for medical marijuana (2009) (1)
- Introduction to Cannabis and Cannabinoid Research (2016) (1)
- Impact of Circulating N-Acylethanolamine Levels with Clinical and Laboratory End Points in Hemodialysis Patients (2021) (1)
- The effects of oleoylethanolamide on feeding behaviour involve hypothalamic oxytocin neurons (2008) (1)
- Erratum: Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat (Psychopharmacology DOI: 10.1007/s00213-008-1104-0) (2011) (1)
- Next Stop for Fatty Acid Amide Hydrolase Inhibitors, the Clinic? (2020) (1)
- N-acylethanolamine acid amide hydrolase is a novel target for drugs against SARS-CoV-2 and Zika virus (2022) (1)
- Feeding Stimulates Sphingosine-1-Phosphate Mobilization in Mouse Hypothalamus (2019) (1)
- Erratum: Improvement of general symptoms in a chronic psychotic patient treated with finasteride: Case report (Pharmacopsychiatry (2008) 41 (115-116)) (2011) (1)
- Reply: Trick or treat from food endocannabinoids? (1998) (1)
- Potentiation of endocannabinoids and other lipid amides prevents hyperalgesia and inflammation in a pre-clinical model of migraine (2022) (1)
- PPAR α mediates acute effects of palmitoylethanolamide on sensory neurons (2012) (1)
- NAPE-specific phospholipase D regulates LRRK2 association with neuronal membranes. (2021) (1)
- Frequent Δ9- tetrahydrocannabinol exposure during adolescence impairs sociability in adult mice exposed to an aversive painful stimulus (2021) (1)
- Corrigendum to “Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus” [Neuroscience 174 (2011) 50–63] (2011) (1)
- Sympathetic activity controls fat-induced OEA signaling in small intestine (2011) (1)
- The endocannabinoid anandamide in CSF is related to the patterns of cannabis use in first-episode schizophrenia (2005) (1)
- Antagonistic actions of prostaglandins E2 and F2 alpha on the isolated lungs of the frog, Rana esculenta L. (1987) (1)
- The Element of Surprise: (2022) (1)
- Cannabinoids in periodontal disease amid the COVID-19 pandemic (2020) (1)
- Fluorine NMR-based assay in living mammalian cells (2015) (1)
- Corrigendum to “Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats” [Neuroscience 168(2) (2010) 371–386] (2011) (1)
- The role of the endogenous cannabinoid system in schizophrenia (2005) (1)
- Endocannabinoids: Discovery of a unique signaling system for regulating sperm function and fertilization. (2001) (1)
- Endogenous acylethanolamides modulates pain perception in mice (2002) (1)
- A Sensitive Ultrahigh-Performance Liquid Chromatography/Tandem Mass Spectrometry Method for the Simultaneous Analysis of Phytocannabinoids and Endocannabinoids in Plasma and Brain. (2022) (1)
- S1670 The Identification of Peroxisome Proliferator-Activated Receptor Alpha-Independent Effects of Oleoylethanolamide On Intestinal Transit in Mice (2008) (1)
- Endogenous cannabinoids and their neurobiological and functional role in schizophrenia spectrum disorders (2004) (1)
- Synthesis and QSAR of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates (2013) (1)
- A Discount on Cannabinoids (2014) (1)
- Endocannabinoid-Mediated Analgesia (2012) (1)
- Antinociceptive Profile of ARN19702, (2-Ethylsulfonylphenyl)-[(2S)-4-(6-fluoro-1,3-benzothiazol-2-yl)-2-methylpiperazin-1-yl]methanone, a Novel Orally Active N-Acylethanolamine Acid Amidase Inhibitor, in Animal Models (2021) (1)
- SYSTEM IN INFLAMMATORY BOWEL DISEASE (2008) (1)
- Altered Fatty Acid Amide Signaling Contributes to Reduced Body Weight and Food Consumption in Liver Fatty Acid Binding Protein Knockout (L-FABP−/−) Mice (2011) (1)
- Fat intake stimulates endocannabinoid mobilization in the small intestine through a cephalic mechanism (2010) (0)
- Chapter 9. Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity (2020) (0)
- ADOLESCENT EXPOSURE TO LOW-DOSE THC DISRUPTS ENERGY BALANCE AND ADIPOSE ORGAN HOMEOSTASIS IN ADULTHOOD (2022) (0)
- The Eicosanoids in Cellular Signaling (1996) (0)
- Title Isotope dilution GC / MS determination of anandamide and other fatty acylethanolamides in rat blood plasma Permalink (1998) (0)
- Nasal accumulation and metabolism of Δ9-tetrahydrocannabinol following aerosol ('vaping') administration in an adolescent rat model. (2022) (0)
- Inhibition of N-acylethanolamine acid amidase reverses effects of chronic binge ethanol drinking on ventral tegmental area dopamine neuron firing (2017) (0)
- Erratum to: Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat (2011) (0)
- Abstracts of the European Behavioural Pharmacology Society Workshop ‘Eating Behaviour and Obesity’, Lecce, 7–9 September 2012 PLENARY LIPID SIGNALS AS FAT SENSORS: THE ROLE OF OLEOYLETHANOLAMIDE IN ENERGY BALANCE BODY WEIGHT LOWERING EFFECT OF GASTRIC BYPASS (RYGB) SURGERY (2017) (0)
- Editorial Board (1992) (0)
- Nasal Accumulation and Metabolism of Δ9-Tetrahydrocannabinol Following Aerosol (‘Vaping’) Administration in Adolescent Rats (2022) (0)
- B37 Aberrant sphingosine-1-phosphate metabolism as druggable target in huntington’s disease (2016) (0)
- Acetyl-CoA Synthetase 1 by SIRT1-mediated Deacetylation of Circadian Control of Fatty Acid Elongation (2014) (0)
- Endocannabinoids and Peripheral Pain (2000) (0)
- Neurophysiology of space travel: energetic solar particles cause cell type-specific plasticity of neurotransmission (2016) (0)
- Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) in complex with non-covalent benzothiazole-piperazine inhibitor ARN19702, in presence of Triton X-100 (2018) (0)
- ERRATA (2012) (0)
- Title Increased Renal 2-Arachidonoylglycerol Level Is Associated with Improved Renal Function in a Mouse Model of Acute Kidney Injury (2016) (0)
- Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of parkinsonism. (2022) (0)
- A TWIN STUDY ON ABNORMALITIES OF ENDOCANNABINOID FUNCTIONING IN SCHIZOPHRENIA AND BIPOLAR DISORDER (2012) (0)
- Expression of a cloned rat histamine H 2 receptor mediating inhibition of arachidonate release and activation of cAMP accumulation ( second messengers / phospholipase A 2 / [ 125 I ] iodoaminopotentidine / Chinese hamster ovary cells ) (0)
- Ion mobility mass spectrometry enhances low-abundance species detection in untargeted lipidomics (2016) (0)
- Adolescent exposure to low-dose Δ9-tetrahydrocannabinol (THC) depletes the ovarian reserve in female mice. (2023) (0)
- CD36 deletion is associated with decreased OEA production in the mouse small intestine (2009) (0)
- Combining galantamine and memantine in dual-target new chemical entities for the treatment of Alzheimer’s disease (2012) (0)
- Tissue Quantification in Human Neonates Using Water-Fat Separated (2013) (0)
- Selective cannabinoid-1 receptor blockade significantly benefits fatty acid and triglyceride 1 metabolism in weight-stable nonhuman primates 2 (2012) (0)
- Title Potentiation of anandamide hypotension by the transport inhibitor , AM 404 Permalink (1997) (0)
- Assay of Monoacylglycerol Lipase Activity. (0)
- Author Correction: Patch clamp-assisted single neuron lipidomics (2018) (0)
- Call for Special Issue Papers: Sex and Gender Differences: Focus on Cannabis and Cannabinoids. (2022) (0)
- Seventh European Workshop on Cannabinoid Research and IACM Eighth Conference on Cannabinoids in Medicine (2016) (0)
- Bidirectional control of phospholipase A 2 activity by Ca 2 / calmodulin-dependent protein kinase II , cAMP-dependent protein kinase , and casein kinase II ( Eicosanolds / nerve terminals / neurotrasmltter release ) (0)
- Complete Acid Ceramidase ablation prevents cancer-initiating cell formation in melanoma cells (2017) (0)
- 566 The cross-talk between lipid mediators and growth factors in the control of wound healing (2016) (0)
- Publisher Correction: Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin (2021) (0)
- Rabbit N-acylethanolamine-hydrolyzing acid amidase (NAAA) with fatty acid (myristate), in presence of Triton X-100 (2018) (0)
- Neural Circuitry and Plasticity in the Adult Vertebrate Inner Retina (1999) (0)
- Microglia Depletion Selectively Eliminates a Singular Form of Hippocampal Long-Term Potentiation (2022) (0)
- Molecular dynamics and mutagenesis studies indicate structural flexibility as a key factor for substrate specificity in FAAH catalysis (2014) (0)
- EHMTI-0141. URB937 as a potential therapeutic option for migraine: evaluation in animal model of migraine (2014) (0)
- Revealing potential plasma lipid biomarkers of cystic fibrosis by mass spectrometry (2009) (0)
- Correction: Brown Adipose Tissue Quantification in Human Neonates Using Water-Fat Separated MRI (2014) (0)
- S23. Symposium: Progress in the Genetics of Psychiatric Disorders (2004) (0)
- Cover Picture: Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability / A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo (ChemMedChem 9/2009) (2009) (0)
- Erratum: Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors (Biological Psychiatry (2011) 69 (633-644)) (2011) (0)
- Arachidonate Derivatives as Endogenous Cannabinoid Substances (1996) (0)
- Title Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice Permalink (2015) (0)
- Intestinal biosynthesis of the satiety-promoting lipid OEA is regulated by feeding (2005) (0)
- Title Effects of peripheral FAAH blockade on NTG-induced hyperalgesia-Evaluation of URB 937 in an animal model of migraine Permalink (2015) (0)
- Python molurus mobilization in small intestine of the Burmese python ( Postprandial increase of oleoylethanolamide (2006) (0)
- Inside Cover: Fluorine NMR‐Based Screening on Cell Membrane Extracts (ChemMedChem 2/2014) (2014) (0)
- Biosynthesis, Storage and Mobilization of Arachidonic Acid (1996) (0)
- Guinea pig N-acylethanolamine-hydrolyzing acid amidase (NAAA) covalently bound to beta-lactam inhibitor ARN726 (2018) (0)
- Retraction Note: Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors (2014) (0)
- Corrigendum to “Lipidomic analysis of endocannabinoid metabolism in biological samples” [J. Chromatogr. B 877 (2009) 2755] (2011) (0)
- Effects of fatty acid amide hydrolase (FAAH) inhibitors on working memory in rats (2015) (0)
- Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety (2018) (0)
- Title Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain Permalink (2016) (0)
- One route to religious ecstasy (1991) (0)
- of Acetyl-coenzyme A Synthetase 1 by SIRT 1 Protein-mediated Deacetylation Circadian Control of Fatty Acid Elongation Gene Regulation : (2014) (0)
- lanthipeptide with marked antinociceptive activity. (2014) (0)
- quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors : Modulation at the N-portion of biphenyl-3-yl alkylcarbamates Permalink (2013) (0)
- Erratum: FAAH deficiency promotes energy storage and enhances the motivation for food (International Journal of Obesity (2012) 36 (477) DOI: 10.1038/ijo.2011.112) (2012) (0)
- Corrigendum to “The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew)” [Physiology & Behavior. Volume (97) 121–124] (2011) (0)
- Role of the anandamide reuptake inhibitor AM404 in the modulation of emotional reactivity in rats (2005) (0)
- Erratum: Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: Modulation at the N-portion of biphenyl-3-yl alkylcarbamates (Journal of Medicinal Chemistry (2008) 51 (3487)) (2009) (0)
- Regulation of satiety by the nuclear receptor PPAR-α. Neuroscience (2005) (0)
- Targeted lipidomics: endocannabinoids and other endolipid modulators (2005) (0)
- Biosynthesis of the anandamide precursor, N-Acylphosphatidylethanolamine, is regulated by Ca2+ and depolarisation in cortical neurons (1994) (0)
- Title Activity-Based Probe for N-Acylethanolamine Acid Amidase Permalink (2015) (0)
- N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats (2020) (0)
- Oleoylethanolamide Stimulates Lipolysis by Activating PPAR-27850 (2017) (0)
- Central administration of reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia. (2009) (0)
- Murine N-acylethanolamine-hydrolyzing acid amidase (NAAA) (2018) (0)
- Innentitelbild: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. 2/2015) (2015) (0)
- Fatty acid amide hydrolase (FAAH) substrate specificity understood via molecular dynamics (2013) (0)
- ROLE OF THE ENDOCANNABINOID SYSTEM IN ISCHEMIA-REPERFUSION RENAL INJURY (2013) (0)
- Title Dysfunctional oleoylethanolamide signaling in a mouse model of Prader-Willi syndrome Permalink (2017) (0)
- Title The fat-induced satiety factor oleoylethanolamide suppresses feeding through central release of oxytocin Permalink (2010) (0)
- Diacylglycerol Lipase- (cid:1) and - (cid:2) Control Neurite Outgrowth in Neuro-2a Cells through Distinct Molecular Mechanisms □ (2011) (0)
- Title Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury (2017) (0)
- DETERMINANTS OF MATERNAL AND INFANTICIDAL BEHAVIOR IN FEMALE MOUSE F1 HYBRIDS (2007) (0)
- Patch clamp-assisted single neuron lipidomics (2017) (0)
- Author Correction: Patch clamp-assisted single neuron lipidomics (2018) (0)
- Editorial Board (2010) (0)
- Fatty acid amide hydrolase inhibition alleviates anxiety-like symptoms in a rat model used to study post-traumatic stress disorder. (2023) (0)
- Sympathetic system controls feeding-induced mobilization of NAPE and OEA in the small intestine (2009) (0)
- Rabbit N-acylethanolamine-hydrolyzing acid amidase (NAAA) covalently bound to beta-lactam inhibitor ARN726, in presence of Triton X-100 (2018) (0)
- Medicinal Cannabis in California: An Interview with Igor Grant, MD (2016) (0)
- A Decision 85 Years in the Making. (2022) (0)
- Assay of Monoacylglycerol Lipase Activity. (2016) (0)
- Comparative Pharmacokinetics of D 9 -Tetrahydrocannabinol in Adolescent and Adult Male Mice s (2020) (0)
- Targeted enhancement of oleoylethanolamide mobilization in proximal small intestine induces across-meal satiety in rats (2008) (0)
- Control of pain initiationby endogenouscannabinoids (1998) (0)
- Functional Foods for Health Promotion : Moving Beyond “ Good Fat , Bad Fat ” Moving Beyond “ Good Fat , Bad Fat ” : The Complex Roles of Dietary Lipids in Cellular Function and Health 1 , 2 (2012) (0)
- Intestinal endocannabinoid metabolism mediates the cephalic control of dietary fat intake (2011) (0)
- A mighty (ochondrial) fi ght? (2014) (0)
- Title Synergistic Effects of Galantamine and Memantine in Attenuating Scopolamine-Induced Amnesia in Mice Permalink (2012) (0)
- Medicinal plants (1994) (0)
- Call for Special Issue Papers: Sex and Gender Differences: Focus on Cannabis and Cannabinoids. (2021) (0)
- Progress in the development of b -lactams as N -Acylethanolamine Acid Amidase (NAAA) inhibitors: Synthesis and SAR study of new, potent N - O -substituted derivatives European Journal of Medicinal Chemistry (2017) (0)
- 12-KETO-EICOSATETRAENOIC ACID 209 Extraction of Lipids (2006) (0)
- MOLECULAR BIOLOGY AND PHARMACOLOGY OF HISTAMINE RECEPTOR SUBTYPES (1992) (0)
- LIPID SIGNALS AS FAT SENSORS: THE ROLE OF OLEOYLETHANOLAMIDE IN ENERGY BALANCE (2012) (0)
- Evidence for a role of endogenous cannabinoids in schizophrenia (2003) (0)
- enhances the ATP-evoked release of acid from mouse astrocytes. (1997) (0)
- Title Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients : Impact of cannabis use Permalink (2007) (0)
- Editorial Board (2007) (0)
- Identification and characterization of carprofen as a multi-target FAAH/COX inhibitor (2013) (0)
- P.2.143 Does cannabis use affect endogenouscannabinoids in schizophrenia? (2004) (0)
- Nogo-a Pathway Contributes to Neural Injury and Pain in Sickle Cell Disease (2021) (0)
- Erratum to: The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat (2011) (0)
- O-(Triazolyl)methyl carbamates as a novel and potent class of FAAH inhibitors (2015) (0)
- Rapid Participation of Prostaglandin E, in Dopamine D2 Receptor-Dependent Potentiation of Arachidonic Acid Release (2006) (0)
- Feeding regulates levels of the satiety mediator oleoylethanolamide in rat small intestine (2004) (0)
- Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) precursor (C126A) (2018) (0)
- Increased OMAR MA1 DV in PTSD (2013) (0)
- Modulating endogenous cannabinoids to treat pain and affective disorders (2008) (0)
- Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'- carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide (2017) (0)
- Title The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease (2011) (0)
- Purification and High-Resolution Analysis of Anandamide and Other Fatty Acylethanolamides (2020) (0)
- Expert Panel on Understanding Cannabis: Medicine, Society, Government (2017) (0)
- Molecular modelling studies on PEA hydrolysis by the enzyme N-acylethanolamine acid amidase (2021) (0)
- P256 The Endocannabinoid System in Inflammatory Bowel Disease (2008) (0)
- P.1.016 N-acylphosphatidylethanolamines: early players in Parkinson’s disease (2017) (0)
- as a feeding regulator in goldfish. (2014) (0)
- Synthesis and Structure - Activity Relationships of N - ( 2-Oxo-3-oxetanyl ) amides as N -Acylethanolamine-hydrolyzing Acid Amidase Inhibitors in activated inflammatory cells and (2010) (0)
- Age-dependent changes in nervonic acid-containing sphingolipids in mouse hippocampus Molecular and cell biology of lipids (2017) (0)
- characterization of the peripheral FAAH inhibitor in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier. (2012) (0)
- N-acylethanolamines in goldfish: feeding regulation and interaction with circadian system (2017) (0)
- The Arachidonic Acid Cascade (1996) (0)
- P007. Inhibition of monoacylglycerol lipase activity modulates the activation of brain structures relevant for migraine pathogenesis (2015) (0)
- Disruption of intestinal OEA biosynthesis and feeding behavior in the rodents fed high fat diet (2017) (0)
- Omega-3 fatty acid deficit in Alzheimer's disease (2009) (0)
- Title An amyloid β 42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer ' s disease Permalink (2012) (0)
- Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of Parkinson’s disease (2022) (0)
- Demystifying Cannabis (2019) (0)
- CS3.5 A KEY ROLE FOR THE ENDOCANNABINOID SYSTEM IN INFLAMMATORY BOWEL DISEASE (2008) (0)
- Title Endogenous cannabinoids and their neurobiological and functional role in schizophrenia spectrum disorders (2017) (0)
- W1168 A Key Role for the Endocannabinoid System in Dampening T Helper Cell Type 1 Response in Inflammatory Bowel Disease (2008) (0)
- Perspectives in Pharmacology Mechanisms of Endocannabinoid Inactivation : Biochemistry and Pharmacology (2017) (0)
- FAAH and soluble epoxide hydrolase inhibitors are ynergistically antinociceptive (2015) (0)
- Title Multitarget Fatty acid amide hydrolase / cyclooxygenase blockade suppresses intestinal inflammation and protects against nonsteroidal anti-inflammatory drug-dependent gastrointestinal damage Permalink (2015) (0)
- Title Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition Permalink (2016) (0)
- P.3.f.001 Does anandamide elevation in cerebrospinal fluid protect against transition into frank psychosis? (2008) (0)
- It is Déjà Vu All Over Again (2019) (0)
- Title Synthesis and structure-activity relationships of FAAH inhibitors : Cyclohexylcarbamic acid biphenyl esters with chemical modulation at the proximal phenyl ring Permalink (2005) (0)
- A role for the endocannabinoid 2-arachidonoyl-sn-glycerol for social and high-fat food reward in male mice (2016) (0)
- Pain relief with anandamide (1999) (0)
- Caenorhabditis elegans N-acylethanolamine-hydrolyzing acid amidase (NAAA) ortholog (2018) (0)
- Title Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor (2017) (0)
- Reply: cannabinoid paths to anti-diarrheal drugs.: cannabinoid paths to anti-diarrheal drugs. (2000) (0)
- Pain relief with endogenous cannabinoid (1999) (0)
- Alterations in plasma endocannabinoids (eCB) in 4-week abstinent alcoholics: A biological marker for hedonic tone? (2007) (0)
- Title Sleep deprivation increases oleoylethanolamide in human cerebrospinal fluid Permalink (2009) (0)
- Elimination de la douleur au moyen de cannabinoides endogenes (1999) (0)
- Synergistic antinociceptive effects of concomitant NAAA and peripheral FAAH inhibition (2022) (0)
- Aspects of Heritability of Altered Endocannabinoid Functioning in Schizophrenia and Bipolar Disorder (2012) (0)
- Scientifically speaking, this drug’s on the wrong list (2005) (0)
- Role of Exogenous and Endogenous Cannabinoids in Psychosis and Cognition Friday, April 30, 2:30 PM-5:00 PM Location: Jade Chair: Deepak Cyril D'Souza 368. Effects on Simulated Driving and Test of Visual Attention (2017) (0)
- Exposure Stimulates Synthesis of the Bioactive Lipid Oleoylethanolamide in Rat Adipose Tissue * (2006) (0)
- Corrigendum: The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease (2011) (0)
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