Daria D. Mochly-rosen
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Daria D. Mochly-rosenbiology Degrees
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Molecular Biology
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#593
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Neuroscience
#693
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Biochemistry
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Biology
Daria D. Mochly-rosen's Degrees
- PhD Biochemistry University of California, San Francisco
- Bachelors Chemistry University of California, Berkeley
Why Is Daria D. Mochly-rosen Influential?
(Suggest an Edit or Addition)Daria D. Mochly-rosen's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Localization of protein kinases by anchoring proteins: a theme in signal transduction. (1995) (938)
- Protein kinase C isozymes and the regulation of diverse cell responses. (2000) (732)
- Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins. (1994) (716)
- Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart (2008) (661)
- Anchoring proteins for protein kinase C: a means for isozyme selectivity. (1998) (606)
- Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC (2001) (515)
- Identification of intracellular receptor proteins for activated protein kinase C. (1991) (499)
- Protein kinase C, an elusive therapeutic target? (2012) (487)
- Targeting aldehyde dehydrogenase 2: new therapeutic opportunities. (2014) (420)
- A Protein Kinase C Translocation Inhibitor as an Isozyme-selective Antagonist of Cardiac Function* (1996) (395)
- A Selective ε-Protein Kinase C Antagonist Inhibits Protection of Cardiac Myocytes from Hypoxia-induced Cell Death* (1997) (376)
- Localization of protein kinase C isozymes in cardiac myocytes. (1994) (366)
- Adaptor proteins in protein kinase C-mediated signal transduction (2001) (364)
- Sustained in vivo cardiac protection by a rationally designed peptide that causes ɛ protein kinase C translocation (1999) (353)
- A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity (2013) (345)
- An Inhibitor of p38 Mitogen-activated Protein Kinase Protects Neonatal Cardiac Myocytes from Ischemia* (1999) (335)
- C2 Region-derived Peptides Inhibit Translocation and Function of β Protein Kinase C in Vivo(*) (1995) (332)
- Chronic Hypersensitivity For Inflammatory Nociceptor Sensitization Mediated by the ε Isozyme of Protein Kinase C (2000) (288)
- Inhibition of &dgr;-Protein Kinase C Protects Against Reperfusion Injury of the Ischemic Heart In Vivo (2003) (278)
- Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration. (2013) (276)
- Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC. (2001) (271)
- Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration (2019) (264)
- Protein Kinase C- ξ is Responsible for the Protection of Preconditioning in Rabbit Cardiomyocytes (1999) (258)
- Evidence of ζ Protein Kinase C Involvement in Polymorphonuclear Neutrophil Integrin-dependent Adhesion and Chemotaxis* (1998) (257)
- Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. (1986) (247)
- The Coatomer Protein β′-COP, a Selective Binding Protein (RACK) for Protein Kinase Cε* (1997) (244)
- Acute Inhibition of Excessive Mitochondrial Fission After Myocardial Infarction Prevents Long‐term Cardiac Dysfunction (2013) (243)
- Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo (2011) (237)
- A protein kinase C isozyme is translocated to cytoskeletal elements on activation. (1990) (230)
- Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation (2018) (229)
- Peptide modulators of protein–protein interactions in intracellular signaling (1998) (218)
- εPKC Is Required for the Induction of Tolerance by Ischemic and NMDA-Mediated Preconditioning in the Organotypic Hippocampal Slice (2003) (212)
- Protein kinase Cdelta activation induces apoptosis in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria. (2004) (210)
- An autoregulatory region in protein kinase C: the pseudoanchoring site. (1995) (207)
- Additive Protection of the Ischemic Heart Ex Vivo by Combined Treatment With &dgr;-Protein Kinase C Inhibitor and &egr;-Protein Kinase C Activator (2003) (205)
- Protein kinase C in heart failure: a therapeutic target? (2008) (205)
- Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C. (2000) (203)
- Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzyme. (1991) (199)
- The Role of Protein Kinase C in Cerebral Ischemic and Reperfusion Injury (2005) (197)
- Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant (2010) (194)
- Chronic ethanol causes heterologous desensitization of receptors by reducing αsmessenger RNA (1988) (185)
- Cardiotrophic Effects of Protein Kinase C ε Analysis by In Vivo Modulation of PKCε Translocation (2000) (185)
- Intracoronary KAI-9803 as an Adjunct to Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction (2008) (182)
- Protein Kinase C δ Mediates Cerebral Reperfusion Injury In Vivo (2004) (181)
- Restoring metabolism of myeloid cells reverses cognitive decline in ageing (2021) (175)
- Mitochondrial aldehyde dehydrogenase and cardiac diseases (2010) (173)
- Translocation Inhibitors Define Specificity of Protein Kinase C Isoenzymes in Pancreatic β-Cells* (1997) (172)
- Correcting mitochondrial fusion by manipulating mitofusin conformations (2016) (167)
- Binding Specificity for RACK1 Resides in the V5 Region of βII Protein Kinase C* (2001) (166)
- Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation. (1999) (161)
- Localization, anchoring, and functions of protein kinase C isozymes in the heart. (2001) (161)
- RACK1, a protein kinase C anchoring protein, coordinates the binding of activated protein kinase C and select pleckstrin homology domains in vitro. (1999) (158)
- Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury. (2007) (158)
- Peptidomimetic therapeutics: scientific approaches and opportunities. (2017) (158)
- Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts. (2002) (157)
- Intracellular transport mechanisms of signal transducers. (2002) (156)
- Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7). (2001) (153)
- Epsilon protein kinase C as a potential therapeutic target for the ischemic heart. (2006) (147)
- PKC isozymes in chronic cardiac disease: possible therapeutic targets? (2008) (146)
- Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: role of epsilon protein kinase C. (1999) (144)
- Mitochondrial reactive oxygen species at the heart of the matter: new therapeutic approaches for cardiovascular diseases. (2015) (143)
- Pharmacologic modulation of protein kinase C isozymes: the role of RACKs and subcellular localisation. (1999) (143)
- MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A (2018) (140)
- A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death. (1997) (139)
- Domain structure and phosphorylation of protein kinase C. (1987) (130)
- Reperfusion-Induced Translocation of &dgr;PKC to Cardiac Mitochondria Prevents Pyruvate Dehydrogenase Reactivation (2005) (126)
- VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease (2016) (124)
- Opposing roles of δ and εPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery (2003) (120)
- Preservation of Base-line Hemodynamic Function and Loss of Inducible Cardioprotection in Adult Mice Lacking Protein Kinase Cϵ* (2004) (118)
- Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells (1994) (116)
- Interaction of protein kinase C with RACK1, a receptor for activated C-kinase: a role in beta protein kinase C mediated signal transduction. (1995) (116)
- Agonists and antagonists of protein kinase C function, derived from its binding proteins. (1994) (116)
- Mitochondrial import of PKCε is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury (2010) (116)
- Cardioprotection by &egr;-Protein Kinase C Activation From Ischemia: Continuous Delivery and Antiarrhythmic Effect of an &egr;-Protein Kinase C-Activating Peptide (2005) (114)
- Aldehyde dehydrogenase 2 in cardiac protection: a new therapeutic target? (2009) (112)
- Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C. (1987) (112)
- Targeting mitochondrial dysfunction and oxidative stress in heart failure: Challenges and opportunities (2018) (109)
- Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator. (2003) (109)
- Modulating protein kinase C signal transduction. (1998) (108)
- Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2. (2009) (107)
- An Inhibitory Fragment Derived from Protein Kinase Cε Prevents Enhancement of Nerve Growth Factor Responses by Ethanol and Phorbol Esters* (1997) (107)
- Protein kinase C delta mediates cerebral reperfusion injury in vivo. (2004) (106)
- Aldehyde dehydrogenase 2 activation in heart failure restores mitochondrial function and improves ventricular function and remodelling. (2014) (106)
- The HIV Nef Protein Associates with Protein Kinase C Theta* (1996) (105)
- Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington’s disease (2015) (105)
- The PKCδ -Abl complex communicates ER stress to the mitochondria – an essential step in subsequent apoptosis (2008) (104)
- Epsilon Protein Kinase C Mediated Ischemic Tolerance Requires Activation of the Extracellular Regulated Kinase Pathway in the Organotypic Hippocampal Slice (2004) (104)
- Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure (2017) (100)
- A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant. (2015) (100)
- Evidence for functional role of εPKC isozyme in the regulation of cardiac Ca2+ channels (2000) (99)
- Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice. (2010) (98)
- Rationally designed peptide regulators of protein kinase C (2009) (98)
- Distinct cellular and regional localization of immunoreactive protein kinase C in rat brain. (1987) (97)
- Protein kinase C-epsilon is responsible for the protection of preconditioning in rabbit cardiomyocytes. (1999) (96)
- Inhibition of the spontaneous rate of contraction of neonatal cardiac myocytes by protein kinase C isozymes. A putative role for the epsilon isozyme. (1995) (95)
- Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis (2018) (94)
- Monoclonal anti-acetylcholine-receptor antibodies directed against the cholinergic binding site. (1981) (94)
- Insight into intra- and inter-molecular interactions of PKC: design of specific modulators of kinase function. (2007) (93)
- p65 fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C. (1992) (93)
- The βγ Subunit of Heterotrimeric G Proteins Interacts with RACK1 and Two Other WD Repeat Proteins* (2002) (92)
- Cardiotrophic effects of protein kinase C epsilon: analysis by in vivo modulation of PKCepsilon translocation. (2000) (92)
- Dopamine-induced exocytosis of Na,K-ATPase is dependent on activation of protein kinase C-ε and -δ (2002) (92)
- Peptides and peptidomimetics as regulators of protein-protein interactions. (2017) (91)
- An improved permeabilization protocol for the introduction of peptides into cardiac myocytes. Application to protein kinase C research. (1996) (90)
- The roles of PKCδ and ϵ isoenzymes in the regulation of myocardial ischaemia/reperfusion injury (2007) (89)
- Aldehyde dehydrogenase activation prevents reperfusion arrhythmias by inhibiting local renin release from cardiac mast cells. (2010) (88)
- Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system (2014) (88)
- C2 Region–Derived Peptides of β-Protein Kinase C Regulate Cardiac Ca2+ Channels (1997) (87)
- Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: a role for MARCKS in an integrin signaling pathway. (2002) (87)
- Binding specificity for RACK1 resides in the V5 region of beta II protein kinase C. (2001) (87)
- Biodistribution of intracellularly acting peptides conjugated reversibly to Tat. (2004) (86)
- Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Phosphorylation by Protein Kinase Cδ (PKCδ) Inhibits Mitochondria Elimination by Lysosomal-like Structures following Ischemia and Reoxygenation-induced Injury* (2013) (85)
- Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain (2014) (84)
- Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease (2017) (83)
- Ischaemic preconditioning improves proteasomal activity and increases the degradation of δPKC during reperfusion (2009) (80)
- Mitochondrial protein kinase Cepsilon (PKCepsilon): emerging role in cardiac protection from ischaemic damage. (2007) (78)
- Opposing roles of delta and epsilonPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery. (2003) (77)
- Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism (2014) (76)
- ALDH2 Activator Inhibits Increased Myocardial Infarction Injury by Nitroglycerin Tolerance (2011) (75)
- Happy birthday protein kinase C: past, present and future of a superfamily. (2007) (74)
- The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon. (1997) (72)
- Involvement of protein kinase Cepsilon (PKCepsilon) in thyroid cell death. A truncated chimeric PKCepsilon cloned from a thyroid cancer cell line protects thyroid cells from apoptosis. (1999) (72)
- Protein Kinase C ϵ and γ: Involvement in Formalin-Induced Nociception in Neonatal Rats (2004) (71)
- Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C. (1994) (71)
- The roles of PKCdelta and epsilon isoenzymes in the regulation of myocardial ischaemia/reperfusion injury. (2007) (71)
- Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy. (2019) (71)
- Cardioprotection by epsilon-protein kinase C activation from ischemia: continuous delivery and antiarrhythmic effect of an epsilon-protein kinase C-activating peptide. (2005) (71)
- Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop (2019) (67)
- Exercise Training Restores Cardiac Protein Quality Control in Heart Failure (2012) (67)
- Sustained inhibition of PKCα reduces intravasation and lung seeding during mammary tumor metastasis in an in vivo mouse model (2010) (66)
- Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases* (2011) (65)
- deltaPKC participates in the endoplasmic reticulum stress-induced response in cultured cardiac myocytes and ischemic heart. (2007) (64)
- Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator (2018) (64)
- Protein Kinase C Delta Cleavage Initiates an Aberrant Signal Transduction Pathway after Cardiac Arrest and Oxygen Glucose Deprivation (2005) (64)
- Nitroglycerin use in myocardial infarction patients. (2012) (64)
- Involvement of a p38 mitogen-activated protein kinase phosphatase in protecting neonatal rat cardiac myocytes from ischemia. (2000) (63)
- Sustained pharmacological inhibition of deltaPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats. (2007) (62)
- Peptides Derived from the C2 Domain of Protein Kinase Cϵ (ϵPKC) Modulate ϵPKC Activity and Identify Potential Protein-Protein Interaction Surfaces* (2006) (62)
- Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis (1996) (62)
- Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through ϵ protein kinase C (2001) (61)
- A Critical Intramolecular Interaction for Protein Kinase Cϵ Translocation* (2004) (59)
- βIIPKC and εPKC isozymes as potential pharmacological targets in cardiac hypertrophy and heart failure. (2011) (59)
- Pharmacological Inhibition of ϵ-Protein Kinase C Attenuates Cardiac Fibrosis and Dysfunction in Hypertension-Induced Heart Failure (2008) (58)
- A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo (2011) (57)
- Opposing Effects of δ and ξ PKC in Ethanol-induced Cardioprotection ☆ (2001) (57)
- δPKC-annexin V interaction; a required step in δPKC translocation and function (2006) (56)
- Impaired perfusion after myocardial infarction is due to reperfusion-induced deltaPKC-mediated myocardial damage. (2007) (55)
- Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy (2020) (55)
- Opposing effects of δ- and ζ-protein kinase C isozymes on cardiac fibroblast proliferation: use of isozyme-selective inhibitors (2003) (54)
- Dopamine and Ethanol Cause Translocation of ϵPKC Associated with ϵRACK: Cross-Talk between cAMP-Dependent Protein Kinase A and Protein Kinase C Signaling Pathways (2008) (54)
- Tissue Angiotensin II During Progression or Ventricular Hypertrophy to Heart Failure in Hypertensive Rats; Differential Effects on PKCε and PKCβ (2002) (54)
- Isozyme-specific inhibitors and activators of protein kinase C. (2002) (53)
- A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats (2019) (52)
- Inhibition of protein kinase C function by injection of intracellular receptors for the enzyme. (1992) (51)
- Mitochondrial aldehyde dehydrogenase-2 activation prevents &bgr;-amyloid-induced endothelial cell dysfunction and restores angiogenesis (2013) (50)
- Suppression of δPKC Activation after Focal Cerebral Ischemia Contributes to the Protective Effect of Hypothermia (2007) (50)
- Dopamine-induced exocytosis of Na,K-ATPase is dependent on activation of protein kinase C-epsilon and -delta. (2002) (50)
- PKCδ activation mediates angiogenesis via NADPH oxidase activity in PC‐3 prostate cancer cells (2011) (48)
- Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: benefits of Alda-1. (2015) (48)
- Pharmacological recruitment of aldehyde dehydrogenase 3A1 (ALDH3A1) to assist ALDH2 in acetaldehyde and ethanol metabolism in vivo (2015) (48)
- Centrosomal PKCbetaII and pericentrin are critical for human prostate cancer growth and angiogenesis. (2008) (48)
- Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo (2018) (48)
- Regulation of mitochondrial processes: a target for heart failure. (2010) (48)
- The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor. (1995) (48)
- Molecular Dynamics Characterization of the C2 Domain of Protein Kinase Cβ* (2002) (47)
- δPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo (2007) (47)
- Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C ε and γ (2004) (47)
- deltaPKC inhibition or varepsilonPKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification. (2010) (46)
- Protein Quality Control Disruption by PKCβII in Heart Failure; Rescue by the Selective PKCβII Inhibitor, βIIV5-3 (2012) (46)
- The Role of Adenosine and Adenosine Transport in Ethanol‐Induced Cellular Tolerance and Dependence (1991) (45)
- Exposure of HeLa DNA polymerase alpha to protein kinase C affects its catalytic properties. (1987) (45)
- The betagamma subunit of heterotrimeric G proteins interacts with RACK1 and two other WD repeat proteins. (2002) (45)
- Stimulus-dependent subcellular localization of activated protein kinase C; a study with acidic fibroblast growth factor and transforming growth factor-beta 1 in cardiac myocytes. (1995) (44)
- Peptides derived from the C2 domain of protein kinase C epsilon (epsilon PKC) modulate epsilon PKC activity and identify potential protein-protein interaction surfaces. (2007) (44)
- Cell-specific role for ε- and βI-protein kinase C isozymes in protecting cortical neurons and astrocytes from ischemia-like injury (2004) (44)
- The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained. (2016) (44)
- Interaction of monoclonal antibodies to torpedo acetylcholine receptor with the receptor of skeletal muscle (1983) (43)
- Matrix metalloproteinases modulated by protein kinase Cε mediate resistin-induced migration of human coronary artery smooth muscle cells. (2011) (42)
- Common ALDH2 genetic variants predict development of hypertension in the SAPPHIRe prospective cohort: Gene-environmental interaction with alcohol consumption (2012) (42)
- The Role of Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) in Neuropathology and Neurodegeneration. (2016) (42)
- Suppression of Graft Coronary Artery Disease by a Brief Treatment With a Selective &egr;PKC Activator and a &dgr;PKC Inhibitor in Murine Cardiac Allografts (2004) (42)
- Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes (2018) (41)
- Mortal engines: Mitochondrial bioenergetics and dysfunction in neurodegenerative diseases. (2018) (41)
- PKC isozyme selective regulation of cloned human cardiac delayed slow rectifier K current. (2003) (40)
- Drp1/Fis1-mediated mitochondrial fragmentation leads to lysosomal dysfunction in cardiac models of Huntington's disease. (2019) (39)
- Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model. (2007) (39)
- Potential biomarkers to follow the progression and treatment response of Huntington’s disease (2016) (39)
- Proteins kinase Cɛ is required for non-small cell lung carcinoma growth and regulates the expression of apoptotic genes (2012) (39)
- RACK1 regulates Src-mediated Sam68 and p190RhoGAP signaling (2004) (38)
- Isozyme-specific abnormalities of PKC in thyroid cancer: evidence for post-transcriptional changes in PKC epsilon. (2002) (37)
- Pharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy. (2011) (37)
- Pharmacological regulation of network kinetics by protein kinase C localization. (2000) (37)
- Mast cells and epsilonPKC: a role in cardiac remodeling in hypertension-induced heart failure. (2008) (37)
- PKC-{epsilon}-dependent survival signals in diabetic hearts. (2005) (36)
- Nociceptive-induced myocardial remote conditioning is mediated by neuronal gamma protein kinase C (2013) (36)
- Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes. (2019) (36)
- Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones (2014) (35)
- β2-adrenergic receptors mediate cardioprotection through crosstalk with mitochondrial cell death pathways. (2011) (35)
- Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta. (2002) (34)
- ALDH1 Bio-activates Nifuroxazide to Eradicate ALDHHigh Melanoma-Initiating Cells (2018) (34)
- Glucose-6-Phosphate Dehydrogenase Deficiency and the Need for a Novel Treatment to Prevent Kernicterus. (2016) (34)
- Ethanol Withdrawal–Associated Allodynia and Hyperalgesia: Age-Dependent Regulation by Protein Kinase Cϵ and γ Ιsozymes (2005) (33)
- Coupling between Protein Stability and Catalytic Activity Determines Pathogenicity of G6PD Variants. (2017) (33)
- New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases (2015) (33)
- Arachidonic acid protects neonatal rat cardiac myocytes from ischaemic injury through epsilon protein kinase C. (2001) (32)
- Selective activation of protein kinase C∊ in mitochondria is neuroprotective in vitro and reduces focal ischemic brain injury in mice (2013) (32)
- Transient Receptor Potential Vanilloid 1 Regulates Mitochondrial Membrane Potential and Myocardial Reperfusion Injury (2016) (32)
- Opposing effects of delta- and zeta-protein kinase C isozymes on cardiac fibroblast proliferation: use of isozyme-selective inhibitors. (2003) (31)
- Regulation of cardiac excitability by protein kinase C isozymes. (2012) (31)
- Surviving in the Valley of Death: Opportunities and Challenges in Translating Academic Drug Discoveries. (2019) (31)
- Identification of εPKC targets during cardiac ischemic injury. (2012) (31)
- Transcriptome analysis and prognosis of ALDH isoforms in human cancer (2018) (31)
- Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes’ toxicity (2020) (30)
- PKCε activation promotes FGF-2 exocytosis and induces endothelial cell proliferation and sprouting. (2013) (30)
- Focus on: The cardiovascular system: what did we learn from the French (Paradox)? (2010) (30)
- Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells. (2016) (30)
- Therapeutic Potential for Protein Kinase C Inhibitor in Vascular Restenosis (2011) (29)
- Cardioprotection induced by a brief exposure to acetaldehyde: role of aldehyde dehydrogenase 2 (2018) (29)
- Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer’s disease related pathology (2019) (29)
- Exaggerated nociceptive responses on morphine withdrawal: roles of protein kinase C epsilon and gamma. (2004) (29)
- Protein kinase Cγ mediates ethanol withdrawal hyper‐responsiveness of NMDA receptor currents in spinal cord motor neurons (2005) (29)
- Evidence for functional role of epsilonPKC isozyme in the regulation of cardiac Ca(2+) channels. (2000) (29)
- Aldehyde dehydrogenase 2*2 knock-in mice show increased reactive oxygen species production in response to cisplatin treatment (2017) (28)
- Opposing effects of delta and xi PKC in ethanol-induced cardioprotection. (2001) (28)
- Highly Specific Modulators of Protein Kinase C Localization: Applications to Heart Failure. (2010) (27)
- δPKC-mediated activation of εPKC in ethanol-induced cardiac protection from ischemia (2005) (27)
- Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: a personal account and progress report on transferring academic discoveries to the clinic. (2007) (27)
- A critical intramolecular interaction for protein kinase Cepsilon translocation. (2004) (27)
- ACETYLCHOLINE RECEPTOR: MOLECULAR DISSECTION AND MONOCLONAL ANTIBODIES IN THE STUDY OF EXPERIMENTAL MY ASTHENIA * (1981) (27)
- Evidence for functional role of epsilonPKC isozyme in the regulation of cardiac Na(+) channels. (2001) (27)
- Distinct responses of protein kinase C isozymes to c-erbB-2 activation in SKBR-3 human breast carcinoma cells. (1994) (26)
- Immunoglobulin Y for Potential Diagnostic and Therapeutic Applications in Infectious Diseases (2021) (26)
- A Novel Aldehyde Dehydrogenase-3 Activator (Alda-89) Protects Submandibular Gland Function from Irradiation without Accelerating Tumor Growth (2013) (25)
- Peripheral Sensitization Increases Opioid Receptor Expression and Activation by Crotalphine in Rats (2014) (25)
- PKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responses (2011) (25)
- Nicotinic acetylcholine receptor desensitization is regulated by activation-induced extracellular adenosine accumulation (1992) (25)
- The identification and purification of a mammalian- like protein kinase C in the yeast Saccharomyces cerevisiae (1991) (25)
- ALDH2 and Cardiovascular Disease. (2019) (25)
- C2 region-derived peptides of beta-protein kinase C regulate cardiac Ca2+ channels. (1997) (24)
- Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo. (2016) (24)
- Protein kinase C delta (deltaPKC)-annexin V interaction: a required step in deltaPKC translocation and function. (2006) (24)
- Prolonged phorbol ester treatment down-regulates protein kinase C isozymes and increases contraction rate in neonatal cardiac myocytes. (1995) (23)
- Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts. (2004) (23)
- PKC-ALDH2 Pathway Plays a Novel Role in Adipocyte Differentiation (2016) (22)
- Mitigation of Radiation-Induced Dermatitis by Activation of Aldehyde Dehydrogenase 2 Using Topical Alda-1 in Mice1 (2012) (22)
- Chronic ethanol causes heterologous desensitization of receptors by reducing alpha s messenger RNA. (1988) (22)
- Characterization of the binding and phosphorylation of cardiac calsequestrin by e protein kinase C1 (1999) (21)
- Differential activation of protein kinase C isozymes by phorbol ester and collagen in human skin microvascular endothelial cells. (1996) (21)
- Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death* (2016) (21)
- Ethanol withdrawal-associated allodynia and hyperalgesia: age-dependent regulation by protein kinase C epsilon and gamma isoenzymes. (2005) (21)
- Use of a novel method to find substrates of protein kinase C delta identifies M2 pyruvate kinase. (2007) (21)
- Sustained Inhibition of &egr; Protein Kinase C Inhibits Vascular Restenosis After Balloon Injury and Stenting (2010) (21)
- A general procedure for screening inhibitory antibodies: application for identifying anti-protein kinase C antibodies. (1988) (20)
- Cell-specific role for epsilon- and betaI-protein kinase C isozymes in protecting cortical neurons and astrocytes from ischemia-like injury. (2004) (20)
- Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor (2017) (20)
- Inhibition of heart transplant injury and graft coronary artery disease after prolonged organ ischemia by selective protein kinase C regulators. (2005) (20)
- ɛPKC confers acute tolerance to cerebral ischemic reperfusion injury (2008) (20)
- RBCK1, a Protein Kinase CβI (PKCβI)-interacting Protein, Regulates PKCβ-dependent Function* (2006) (19)
- Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes (2018) (18)
- In Vivo Post–Cardiac Arrest Myocardial Dysfunction Is Supported by Ca2+/Calmodulin-Dependent Protein Kinase II–Mediated Calcium Long-Term Potentiation and Mitigated by Alda-1, an Agonist of Aldehyde Dehydrogenase Type 2 (2016) (17)
- In vivo measurement of aldehyde dehydrogenase‐2 activity in rat liver ethanol model using dynamic MRSI of hyperpolarized [1‐13C]pyruvate (2013) (17)
- Aldehyde dehydrogenase 2 activation and coevolution of its εPKC-mediated phosphorylation sites (2017) (17)
- Small‐Molecule Activators of Glucose‐6‐phosphate Dehydrogenase (G6PD) Bridging the Dimer Interface (2019) (17)
- Developmental expression of protein kinase C subspecies in rat brain-pituitary axis (1994) (17)
- A Practical Guide to Drug Development in Academia (2014) (16)
- DeltaPKC-mediated activation of epsilonPKC in ethanol-induced cardiac protection from ischemia. (2005) (16)
- Rational design of a selective antagonist of epsilon protein kinase C derived from the selective allosteric agonist, pseudo-RACK peptide. (2007) (15)
- Genetic Polymorphisms of Alcohol Metabolizing Enzymes and Alcohol Consumption are Associated With Asymptomatic Cardiac Remodeling and Subclinical Systolic Dysfunction in Large Community-Dwelling Asians (2017) (15)
- Ethanol for cardiac ischemia: the role of protein kinase c (2008) (15)
- Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese (2016) (15)
- State-specific Monoclonal Antibodies Identify an Intermediate State in Epsilon Protein Kinase C Activation* (2004) (15)
- Immune regulation of experimental myasthenia. (1980) (15)
- Targeting aldehyde dehydrogenase activity in head and neck squamous cell carcinoma with a novel small molecule inhibitor. (2017) (15)
- Peptide inhibitors of protein-protein interactions: From rational design to the clinic (2010) (15)
- Chronic ethanol-induced heterologous desensitization is mediated by changes in adenosine transport. (1990) (15)
- Paired SARS-CoV-2 spike protein mutations observed during ongoing SARS-CoV-2 viral transfer from humans to minks and back to humans (2020) (14)
- The many hats of protein kinase Cδ: one enzyme with many functions. (2014) (14)
- Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19 (2022) (13)
- Peptide modulators of Src activity in G1 regulate entry into S phase and proliferation of NIH 3T3 cells. (2007) (13)
- Islet cell survival during isolation improved through protein kinase C epsilon activation. (2008) (13)
- Abstract 13618: Sustained Inhibition of Epsilon Protein Kinase C Inhibits Vascular Restenosis After Balloon Injury and Stenting (2010) (13)
- Myocardial salvage in acute myocardial infarction--challenges in clinical translation. (2011) (13)
- Disruption of mitochondrial quality control in peripheral artery disease: New therapeutic opportunities (2017) (12)
- Long-range structural defects by pathogenic mutations in most severe glucose-6-phosphate dehydrogenase deficiency (2021) (12)
- Nitroglycerin Use in Myocardial Infarction Patients: Risks and Benefits (2012) (12)
- Engineered Substrate-Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics. (2016) (12)
- Glutathione S-transferase pull-down assay. (2003) (12)
- Alteration of gene expression during progression of hypertension-induced cardiac dysfunction in rats. (2008) (12)
- Antigenic specificity of acetylcholine receptor in developing muscle Studies with monoclonal antibodies (1985) (12)
- Cytotoxicity of pEGFP vector is due to residues encoded by multiple cloning site. (2003) (12)
- Overlay method for detecting protein-protein interactions. (2003) (11)
- Protein Kinase Cδ Activation Induces Apoptosis in Response to Cardiac Ischemia and Reperfusion Damage (2004) (11)
- Preserved coronary endothelial function by inhibition of delta protein kinase C in a porcine acute myocardial infarction model. (2009) (10)
- Structural analysis of clinically relevant pathogenic G6PD variants reveals the importance of tetramerization for G6PD activity (2017) (10)
- Natural variants in SARS-CoV-2 Spike protein pinpoint structural and functional hotspots with implications for prophylaxis and therapeutic strategies (2021) (10)
- Aldehyde dehydrogenase activator attenuates diabetic cardiomyopathy; a role in improving the quality of resident cardiac stem cells? (2010) (10)
- Activating δPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats (2009) (9)
- RBCK1, a protein kinase CbetaI (PKCbetaI)-interacting protein, regulates PKCbeta-dependent function. (2007) (9)
- Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants’ spike protein–an in silico analysis (2021) (8)
- RSA 2004: combined basic research satellite symposium - session three: alcohol and mitochondrial metabolism: at the crossroads of life and death. (2005) (8)
- δPKC inhibition or εPKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification (2013) (8)
- The challenge in translating basic research discoveries to treatment of Huntington disease (2014) (8)
- Affordable IgY-based antiviral prophylaxis for resource-limited settings to address epidemic and pandemic risks (2022) (7)
- Treatment strategies for glucose-6-phosphate dehydrogenase deficiency: past and future perspectives. (2021) (7)
- ALDH2 deficiency induces atrial fibrillation through dysregulated cardiac sodium channel and mitochondrial bioenergetics: a multi-omics analysis. (2021) (7)
- Non-volume-loaded heart provides a more relevant heterotopic transplantation model. (2010) (7)
- Activation of εPKC reduces reperfusion arrhythmias and improves recovery from ischemia: optical mapping of activation patterns in the isolated guinea-pig heart. (2012) (7)
- Modification of acetylcholine receptor: chemical and immunological characterization of polyalanyl acetylcholine receptor (1980) (6)
- Antibodies to the Acetylcholine Receptor (1984) (6)
- New Therapeutic Approaches for Cardiovascular Diseases (2015) (6)
- ALDH2 variance in disease and populations (2022) (6)
- Scaffold proteins LACK and TRACK as potential drug targets in kinetoplastid parasites: Development of inhibitors (2016) (6)
- Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1 (2022) (6)
- Translational medicine: mitigating risks for investigators (2013) (6)
- Annotation of 1350 Common Genetic Variants of the 19 ALDH Multigene Family from Global Human Genome Aggregation Database (gnomAD) (2021) (5)
- Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCε) knockout mice (2010) (5)
- Monoclonal antibodies modify acetylcholine-induced ionic channel properties in cultured chick myoballs (2005) (5)
- Anchoring proteins for protein kinase C: a means for isozyme selectivity (1998) (5)
- Alcohol Consumption, ALDH2 Polymorphism as Risk Factors for Upper Aerodigestive Tract Cancer Progression and Prognosis (2022) (5)
- Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants (2022) (5)
- GTP-binding proteins are restricted to signal transduction sites. (1990) (5)
- A Possible Physiological Role of Acetylcholine Receptor on Mouse Thymocytes (1983) (4)
- Focus On: The Cardiovascular System (2010) (4)
- Thiophene bridged aldehydes (TBAs) image ALDH activity in cells via modulation of intramolecular charge transfer† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03017g Click here for additional data file. (2017) (4)
- Activation of PKCε-ALDH2 Axis Prevents 4-HNE-Induced Pain in Mice (2021) (4)
- A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice (2021) (4)
- Spontaneous occurrence of an inhibitor of protein kinase C localization in a thyroid cancer cell line: role in thyroid tumorigenesis. (2001) (4)
- Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation. (2022) (4)
- Natural variants in SARS-CoV-2 S protein pinpoint structural and functional hotspots: implications for prophylaxis and therapeutic strategies (2021) (4)
- Molecular Genetic Approaches II (1998) (4)
- An anti‐acetylcholine receptor monoclonal antibody cross‐reacts with phosvitin (1983) (4)
- Molecular genetic approaches. II. Expression-interaction cloning. (1998) (3)
- A Selective Inhibitor of Cardiac Troponin I Phosphorylation by Delta Protein Kinase C (δPKC) as a Treatment for Ischemia-Reperfusion Injury (2022) (3)
- Protein quality control disruption by PKCbetaII in heart failure (2012) (3)
- Drp1/Fis1-Dependent Pathologic Fission and Associated Damaged Extracellular Mitochondria Contribute to Macrophage Dysfunction in Endotoxin Tolerance (2022) (3)
- Acute capsaicin treatment reduces myocardial infarct size in rats via the transient receptor potenti (2010) (3)
- The Role of Alcohol, LPS Toxicity, and ALDH2 in Dental Bony Defects (2021) (3)
- Involvement of Protein Kinase Cε (PKCε) in Thyroid Cell Death (1999) (3)
- 23 Delta PKC in cerebral ischemic and reperfusion injury in vivo (2002) (3)
- Cardioprotection caused by ischemic preconditioning or by an alpha 1-adrenergic receptor agonist is blocked in hearts from Epsilon Protein Kinase C knockout mice (2002) (2)
- Induced Fit and Wit: Celebrating the Life of Daniel E. Koshland, Jr. (1920 ‐ 2007) (2007) (2)
- Protein Kinase C δ (δPKC)-Annexin V Interaction (2006) (2)
- Activation of Aldehyde Dehydrogenase 2 Ameliorates Glucolipotoxicity of Pancreatic Beta Cells (2021) (2)
- Abstract 376: Ischemic Preconditioning Regulates Myocardial Viability Through The Proteasomal Regulation Of Two Opposing PKC Isozymes (2008) (2)
- The Effect of Ethanol Consumption on Composition and Morphology of Femur Cortical Bone in Wild-Type and ALDH2*2-Homozygous Mice (2020) (2)
- Abstract 5363: Sustained Pharmacological {beta}IIPKC Inhibition Is Cardioprotective In Late-stage Hypertrophy And End-stage Heart Failure In Two Rat Models (2008) (2)
- Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes (2018) (1)
- Commercialization and Entrepreneurship (2014) (1)
- GAPDH oligomerization as a switch for its functions 1 GAPDH ( glyceraldehyde-3-phosphate dehydrogenase ) Protein-Protein Interaction Inhibitor Reveals a Non-Catalytic Role for GAPDH Oligomerization in Cell Death (2016) (1)
- A75. Nanoparticles: Novel cardioprotective devices that utilize a preconditioning-like mechanism (2006) (1)
- 22 A role for delta PKC in cardiac reperfusion injury in vivo (2002) (1)
- Molecular aspects of experimental autoimmune myasthenia gravis. (1981) (1)
- Aldehyde dehydrogenase 2*2 knock-in mice show increased reactive oxygen species production in response to cisplatin treatment (2017) (1)
- Alcohol consumption and vascular disease: other points to consider (2019) (1)
- The Effect of Ethanol Consumption on Composition and Morphology of Femur Cortical Bone in Wild-Type and ALDH2*2-Homozygous Mice (2020) (1)
- 21 Enhanced protection of the ischemic heart by combined treatment with δPKC inhibitor and εPKC activator (2002) (1)
- Inhibition of Epsilon Protein Kinase C Attenuates Cardiac Mast Cell Degranulation and Remodeling in Hypertension Induced Heart Failure (2008) (1)
- ALDH2 Expression, Alcohol Intake and Semen Parameters among East Asian Men (2022) (1)
- A novel inhibitor of _protein kinase-C as a therapeutic for ischemic reperfusion injury in acute coronary syndromes (2002) (1)
- Methods for detecting binding proteins: an introduction. (2003) (1)
- Pharmacologic Activation of Aldehyde Metabolism to Protect Hematopoietic Stem Cells (HSC) in Murine Models of Fanconi Anemia (FA) (2019) (1)
- A81. Ischemic preconditioining decreases delta PKC levels resulting in diminished translocation during reperfusion (2006) (1)
- New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases (2015) (1)
- DE NOVO NAD+ SYNTHESIS RESCUES NEUROINFLAMMATION AND ALZHEIMER’S DISEASE PHENOTYPES: MODULATING IMMUNE CELL RESPONSES AND MITOCHONDRIAL BIOENERGETICS (2018) (1)
- Activation of Aldehyde Dehydrogenase 2 Reduces Nitroglycerin‐Induced Cardiac Damage (2010) (1)
- Elucidation of the role of glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) interaction with mutant huntingtin (mtHtt) for mitochondrial elimination in Huntington's disease (2015) (1)
- Increasing Cases of SARS-CoV-2 Omicron Reinfection Reveals Ineffective Post-COVID-19 Immunity in Denmark and Conveys the Need for Continued Next-Generation Sequencing (2022) (1)
- Discovery and Preclinical Work (2013) (1)
- Human Chitotriosidase Does Not Catabolize Hyaluronan. (2018) (1)
- Regulation of PKC by Protein–Protein Interactions in Cancer (2010) (1)
- PEPTIDES DERIVED FROM THE C2 DOMAIN OF (cid:2) PKC MODULATE (cid:2) PKC ACTIVITY AND IDENTIFY POTENTIAL PROTEIN-PROTEIN INTERACTION SURFACES (2006) (0)
- Aprotein kinase Cisozyme istranslocated tocytoskeletal elements on activation (1990) (0)
- 134: MITOCHONDRIAL FISSION & CELL-FREE MITOCHONDRIA MEDIATE CARDIAC DYSFUNCTION IN OBESITY CARDIOMYOPATHY (2022) (0)
- Altering substrate specificity of aldehyde dehydrogenase 3A1 to enhance acetaldehyde metabolism, in vivo (585.9) (2014) (0)
- Combined treatment with epsilon protein kinase C activator and delta protein kinase C inhibitor ameliorates ischemia reperfusion injury and graft coronary artery disease in murine cardiac allografts (2004) (0)
- Abstract 5061: ALDH2 restricts esophageal stem/progenitor cell expansion via autophagy under alcohol-induced mitochondrial stress (2018) (0)
- OE-005 Additive Protection of Ischemic Heart by Combined Treatment with a Delta PKC Inhibitor and an Epsilon PKC Activator(Acute Myocardial Infarction, Basic 1 (IHD) : OE1)(Oral Presentation (English)) (2004) (0)
- Role of Protein Kinase C in Mitochondrial Functions in Cardiac Ischemia- Reperfusion Injury (2012) (0)
- 2 . 1 Robustness of Preclinical Studies (2019) (0)
- Antiarrhythmic Effect of an-Protein Kinase C Activation From Ischemia : Continuous Delivery ε Cardioprotection by Print (2004) (0)
- Conservation: Homes on the range (2008) (0)
- Astronomy: Fossils on Titan (2008) (0)
- 41: ROLE OF DRP1/FIS1-MEDIATED MITOCHONDRIAL FRAGMENTATION IN SEPSIS-INDUCED MYOCARDIAL DYSFUNCTION (2019) (0)
- Berichtigung: Engineered Substrate‐Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics (2017) (0)
- Characterization of a Human ALDH2 Mutant that Causes Alcohol Flushing in Non‐east Asians (2020) (0)
- A Noncanonical Role of Delta Protein Kinase C (δPKC) Phosphorylation of Troponin I in Cardiac Reperfusion Injury (2019) (0)
- Abstract 4748: Identifying PKC Epsilon as a Target Molecule to Control Intimal Hyperplasia (2009) (0)
- Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy (2020) (0)
- Phenotyping aldehyde metabolism in humans uncovers novel genetic mutations in aldehyde dehydrogenase 2 (2020) (0)
- Protein Kinase Cε Regulates Histone Deacetylase 6 in Cardiac Fibrosis (2008) (0)
- 1693: MITOCHONDRIAL DYSFUNCTION MEDIATED THROUGH DRP1-FIS1 INTERACTION PROPAGATES SEPTIC ENCEPHALOPATHY (2020) (0)
- Preparing for the Clinic (2014) (0)
- 1517: EVALUATION OF THE TEMPORAL CHANGES IN CARDIAC BIOENERGETICS IN THE SETTING OF SEPSIS (2018) (0)
- Biochemistry: Protecting the heart (2008) (0)
- Author Correction: Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration (2020) (0)
- Phenotyping genetic differences in aldehyde dehydrogenase 2 after an alcohol challenge in humans (2020) (0)
- Abstract 3782: {beta}2-Adrenergic Receptor Signaling Positively Modulates Pro-Survival Kinases and Ameliorates Mitochondrial Dysfunction during Doxorubicin Cardiotoxicity (2008) (0)
- Coevolution and Disease‐Causing Mutations in Glucose‐6‐Phosphate Dehydrogenase (G6PD) (2016) (0)
- Attenuation of Diabetic Cardiomyopathy Using Small Molecule Activators of Aldehyde Dehydrogenase (2010) (0)
- Genetic variations of aldehyde dehydrogenase 2 and alcohol dehydrogenase 1B are associated with the etiology of atrial fibrillation in Japanese (2016) (0)
- Mitochondrial import of PKC epsilon is mediated by the HSP90-TOM pathway: role in cardioprotective signaling (2007) (0)
- Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration (2019) (0)
- Correcting glucose-6-phosphate dehydrogenase deficiency with a small-molecule activator (2018) (0)
- Abstract 17443: Inhibition of the Calcineurin Interaction Site on TRPV1 Reduces Myocardial Infarct Size in Rats (2014) (0)
- cPKC isozyme specific substrates in murine embryonic stem cells. (2008) (0)
- Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy. (2023) (0)
- Structural defect leads to human severe (Class I) loss of function in glucose‐6‐phosphate dehydrogenase (2020) (0)
- RBCK1, a protein kinase C βI binding partner and its splice variant RBCK2: potential role in cardiac hypertrophy? (2003) (0)
- Engineering a delta protein kinase C inhibitor that selectively inhibits interaction and phosphorylation of one substrate of the multi‐substrate kinase (582.3) (2014) (0)
- 93 Activation of Aldehyde Dehydrogenase Type 2 (ALDH2) by Alda-1 Significantly Enhances the Function of the DCD Heart (2012) (0)
- endothelial cell dysfunction and restores angiogenesis 2 3 (2013) (0)
- Abstract 3749: Novel aldehyde dehydrogenase inhibitors as potential anti-chemoresistance drugs for head and neck cancers (2014) (0)
- SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant (2023) (0)
- Crystal structure of glucose-6-phosphate dehydrogenase W509A mutant in complex with catalytic NADP+ (2021) (0)
- Protection against mammary tumor metastasis by inhibition of PKCα (2007) (0)
- Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation (2018) (0)
- Cardiac Troponin I Directly Binds and Inhibits Mitochondrial ATP Synthase: a Noncanonical Role in the Post-Ischemic Heart (2023) (0)
- A novel pharmacological modulator abrogates physiological mitochondrial fission though specifically inhibiting the Mff‐Drp1 protein‐protein interaction (2018) (0)
- Cardioprotection by (cid:1) -Protein Kinase C Activation From Ischemia Continuous Delivery and Antiarrhythmic Effect of an (cid:1) -Protein Kinase C–Activating Peptide (2004) (0)
- Extracellular release of damaged mitochondria induced by cytotoxic conditioning exacerbates GVHD (2023) (0)
- Proteasomal alterations in the ratios of two novel PKC isoforms regulates myocardial injury following ischemia/reperfusion (2007) (0)
- Abstract 219: Diabetes-induced Mitochondrial Dna Damage and Cardiac Dysfunction are Aggravated Due to Low Aldehyde Dehydrogenase 2 (aldh2) Activity in Aldh 2*2 (e487k) Knock-in Mutant Mice (2015) (0)
- MONOTERPENE ACTIVATORS OF ALDEHYDE DEHYDROGENASE 3A1 AND METHODS OF USE THEREOF (2019) (0)
- Abstract 145: Rational Design of a Novel Peptide That Selectively Inhibits δPkc-mediated Pyruvate Dehydrogenase Kinase Phosphorylation Induce Protection From Ischemia and Reperfusion Injury (2017) (0)
- Abstract 3879: Activation of Aldehyde Dehydrogenase 2 Confers Cardioprotection In Protein Kinase C Epsilon Knockout Mice (2008) (0)
- δPKC inhibition during ishchemia and reperfusion: targeting BAD and the cell death machinery (2003) (0)
- 51: Identifying PKC Epsilon as a Target Molecule To Control Intimal Hyperplasia (2009) (0)
- COVID-19 prophylaxis with immunoglobulin Y (IgY) for the world population: The critical role that governments and non-governmental organizations can play (2022) (0)
- Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible SARS-CoV-2 variants’ spike protein: Analysis of the new UK and SA SARS-CoV-2 variants (2021) (0)
- to the Heart Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage (2014) (0)
- A common East Asian-specific ALDH2 mutation causes obesity and insulin resistance: therapeutic effect of reducing toxic aldehydes by ALDH2 activation (2020) (0)
- Stanford Medicine Surprising Finding Could Change Views on Double Mastectomy (2014) (0)
- Inhibition of angiogenesis and tumor growth by inhibitors of beta ii or delta protein kinase c (2007) (0)
- Common Non‐East Asian Aldehyde Dehydrogenase 2 Deficiencies; Potential Drug Target for Alzheimer's Disease and Mitochondrial Dysfunction (2019) (0)
- ALDH2 dysfunction accelerates ESCC pathogenesis (2023) (0)
- Postnatal cardiac hypertrophy is modulated by εPKC activity (2003) (0)
- 1051-131 Combined treatment with epsilon protein kinase C activator and delta protein kinase C inhibitor ameliorates ischemia reperfusion injury with prolonged ischemia in rat cardiac allografts (2004) (0)
- 1136-81 Epsilon protein kinase C (PKC) activation by delta PKC in ethanol-induced cardiac protection from ischemia (2004) (0)
- Mast Cells, the Allergic Responders, a Target of Heart Failure Therapy? (2008) (0)
- 4-HNE-mediated post-translational modulation of DICER in heart failure (2018) (0)
- BLOOD-BRAIN BARRIER INTEGRITY IN HYPERTENSIVE SUBJECTS USINGA DELTA-PKC INHIBITOR (2017) (0)
- Transcriptome analysis and prognosis of ALDH isoforms in human cancer (2018) (0)
- Abstract 388: High-throughput Single Cell Tracking of Mitochondrial Function in Cardiomyocytes (2015) (0)
- Delivery of a deltaPKC inhibitor peptide improves stroke survival in a rat model of hypertension, and increases cerebral blood flow following transient focal ischemia in normotensive rats (2005) (0)
- δPKC-Mediated DRP1 Phosphorylation Impacts Macrophage Mitochondrial Function and Inflammatory Response to Endotoxin (2021) (0)
- Corrigendum: Engineered Substrate-Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics. (2017) (0)
- Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo (2018) (0)
- 05 Acetylcholine-induced production of reactive oxygen species in A7r5 cells is dependent on protein kinase C (2002) (0)
- 1236: DRP1/P53 INTERACTION PLAYS A KEY ROLE IN MITOCHONDRIAL DYSFUNCTION OF SEPTIC CARDIOMYOPATHY (2022) (0)
- Evolution: Sexy and doomed (2008) (0)
- Abstract 15589: Protein-Protein Inhibitor Peptide of Drp1/Fis1 Interaction Protects the Heart Against Ischemia/Reperfusion Injury (2013) (0)
- aldehydes ( TBAs ) image ALDH activity in cells via modulation of intramolecular charge transfer † (2017) (0)
- A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats (2019) (0)
- PO389 ALDH2 IS A POSITIVE REGULATOR OF ADIPOCYTE DIFFERENTIATION (2014) (0)
- Active aphids (2008) (0)
- Analysis of well-annotated next-generation sequencing data reveals increasing cases of SARS-CoV-2 reinfection with Omicron (2023) (0)
- ALDH7A1 rs12514417 polymorphism may increase ischemic stroke risk in alcohol-exposed individuals (2022) (0)
- Aldehyde dehydrogenase 2 activation and coevolution of its εPKC-mediated phosphorylation sites (2017) (0)
- Methods for Detecting Binding Proteins (2003) (0)
- 1281: EXTRACELLULAR MITOCHONDRIA EXACERBATE GRAFT-VERSUS-HOST DISEASE MORTALITY IN A MOUSE MODEL (2022) (0)
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