Daved H. Fremont
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American professor
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Engineering Computer Science
Daved H. Fremont's Degrees
- Masters Computer Engineering Stanford University
- Bachelors Electrical Engineering University of California, Berkeley
Why Is Daved H. Fremont Influential?
(Suggest an Edit or Addition)According to Wikipedia, Daved H. Fremont is a professor at the Washington University School of Medicine in St. Louis with dual appointments in the Departments of Pathology and Immunology/Biochemistry and Molecular Biophysics. He is currently director of the Computational and Molecular Biophysics Program. Fremont is also a principal investigator in the Center for Structural Genomics of Infectious Disease and his laboratory has deposited structures of proteins from several major human pathogens to the protein data bank .
Daved H. Fremont's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb. (1994) (871)
- Recognition of a virus-encoded ligand by a natural killer cell activation receptor (2002) (807)
- Emerging principles for the recognition of peptide antigens by MHC class I molecules. (1992) (734)
- Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies (2021) (702)
- Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization (2021) (570)
- Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus (2005) (505)
- A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies (2020) (435)
- Structures of an MHC Class II Molecule with Covalently Bound Single Peptides (1996) (409)
- High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling. (1998) (350)
- Structural basis of West Nile virus neutralization by a therapeutic antibody (2005) (345)
- A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2 (2020) (340)
- Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice (2016) (338)
- Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins (2008) (332)
- Structural Basis of Zika Virus-Specific Antibody Protection (2016) (317)
- Cutting Edge: Murine UL16-Binding Protein-Like Transcript 1: A Newly Described Transcript Encoding a High-Affinity Ligand for Murine NKG2D1 (2002) (304)
- Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors (2003) (301)
- Antibody Recognition and Neutralization Determinants on Domains I and II of West Nile Virus Envelope Protein (2006) (299)
- The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection. (2007) (296)
- Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes (2007) (269)
- Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. (1998) (268)
- Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove. (1995) (264)
- Crystal Structure of the West Nile Virus Envelope Glycoprotein (2006) (257)
- An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies (2022) (251)
- Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus (2013) (246)
- Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development. (2008) (238)
- Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc γ Receptor-Dependent and -Independent Mechanisms (2006) (230)
- West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H (2006) (229)
- Discovery of a proteinaceous cellular receptor for a norovirus (2016) (217)
- Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice. (2000) (213)
- The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1 (2010) (212)
- Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. (2008) (205)
- Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2 (2020) (204)
- Mxra8 is a receptor for multiple arthritogenic alphaviruses (2018) (204)
- An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies (2021) (203)
- Structure and Function Analysis of Therapeutic Monoclonal Antibodies against Dengue Virus Type 2 (2010) (202)
- Accessory protein recruitment motifs in clathrin-mediated endocytosis. (2002) (201)
- Structural basis for the preferential recognition of immature flaviviruses by a fusion‐loop antibody (2009) (198)
- Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity. (2001) (194)
- Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist (2017) (190)
- Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2. (2020) (182)
- Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly. (1999) (181)
- Crystal Structure of the Japanese Encephalitis Virus Envelope Protein (2011) (180)
- Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus (2007) (178)
- Identification of a Gammaherpesvirus Selective Chemokine Binding Protein That Inhibits Chemokine Action (2000) (176)
- Structure and Intracellular Targeting of the SARS-Coronavirus Orf7a Accessory Protein (2005) (165)
- MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution (2009) (160)
- Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor (2017) (160)
- Evidence for MR1 Antigen Presentation to Mucosal-associated Invariant T Cells* (2005) (159)
- A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection (2020) (158)
- Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion (2020) (148)
- Genotype-Specific Neutralization and Protection by Antibodies against Dengue Virus Type 3 (2010) (147)
- Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice (2020) (142)
- Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization (2020) (141)
- Oncogenic potential of the DNA replication licensing protein CDT1 (2002) (141)
- Antibody Recognition of Cell Surface-Associated NS1 Triggers Fc-γ Receptor-Mediated Phagocytosis and Clearance of West Nile Virus-Infected Cells (2007) (140)
- Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress (2015) (140)
- MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells (2008) (139)
- Evidence for a Genetic and Physical Interaction between Nonstructural Proteins NS1 and NS4B That Modulates Replication of West Nile Virus (2012) (137)
- The structural immunology of antibody protection against West Nile virus (2008) (132)
- Neutralizing Monoclonal Antibodies against Hepatitis C Virus E2 Protein Bind Discontinuous Epitopes and Inhibit Infection at a Postattachment Step (2011) (130)
- Costimulation through NKG2D Enhances Murine CD8+ CTL Function: Similarities and Differences between NKG2D and CD28 Costimulation1 (2005) (126)
- Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion (2017) (123)
- West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody (2006) (120)
- Antigen‐specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis (2007) (120)
- Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner. (2007) (119)
- Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor (2002) (113)
- In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains (2021) (112)
- Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites (2015) (112)
- RANKL employs distinct binding modes to engage RANK and the osteoprotegerin decoy receptor. (2012) (111)
- Structural basis of Flavivirus NS1 assembly and antibody recognition (2014) (110)
- N-domain–dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation (2004) (105)
- Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope (2012) (103)
- A Therapeutic Antibody against West Nile Virus Neutralizes Infection by Blocking Fusion within Endosomes (2009) (101)
- Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2 (2020) (101)
- Biochemical Features of the MHC-Related Protein 1 Consistent with an Immunological Function1 (2003) (101)
- Crystal structure of mouse H2-M. (1998) (100)
- The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse. (2007) (97)
- Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. (2008) (97)
- Molecular Basis for Recognition of an Arthritic Peptide and a Foreign Epitope on Distinct MHC Molecules by a Single TCR1 (2000) (92)
- Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus. (2009) (91)
- Endogenous MHC-Related Protein 1 Is Transiently Expressed on the Plasma Membrane in a Conformation That Activates Mucosal-Associated Invariant T Cells (2011) (89)
- Ligands for murine NKG2D display heterogeneous binding behavior. (2002) (88)
- In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains. (2021) (83)
- Structural definition of the F-actin–binding THATCH domain from HIP1R (2006) (80)
- Functional Analysis of Antibodies against Dengue Virus Type 4 Reveals Strain-Dependent Epitope Exposure That Impacts Neutralization and Protection (2013) (79)
- A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1. (2009) (78)
- Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets (2021) (77)
- Structural and Functional Consequences of Altering a Peptide MHC Anchor Residue1 (2001) (76)
- Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor (2019) (76)
- SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike (2020) (76)
- Structural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus Release (2010) (76)
- Dual Engagement Regulation of Protein Interactions with the AP-2 Adaptor α Appendage* (2004) (73)
- SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies (2021) (71)
- Biophysical studies of T-cell receptors and their ligands. (1996) (70)
- A single intranasal or intramuscular immunization with chimpanzee adenovirus vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters (2020) (69)
- Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor (2018) (69)
- An infectious SARS-CoV-2 B.1.1.529 Omicron virus escapes neutralization by several therapeutic monoclonal antibodies (2021) (69)
- Capturing a Flavivirus Pre-Fusion Intermediate (2009) (68)
- An intranasal vaccine durably protects against SARS-CoV-2 variants in mice (2021) (68)
- A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques (2021) (66)
- Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains (2022) (66)
- A Short N-Terminal Peptide Motif on Flavivirus Nonstructural Protein NS1 Modulates Cellular Targeting and Immune Recognition (2010) (62)
- Patterns of nonclassical MHC antigen presentation (2007) (62)
- Enhanced Immune Presentation of a Single-chain Major Histocompatibility Complex Class I Molecule Engineered to Optimize Linkage of a C-terminally Extended Peptide* (2003) (60)
- Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association. (1993) (60)
- The unusual dynamics of parasite actin result from isodesmic polymerization (2013) (59)
- Structural principles of MHC class II antigen presentation. (1999) (57)
- A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope (2021) (56)
- The Chemokine Binding Protein M3 Prevents Diabetes Induced by Multiple Low Doses of Streptozotocin1 (2007) (53)
- Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. (2020) (53)
- Soluble class I MHC with beta2-microglobulin covalently linked peptides: specific binding to a T cell hybridoma. (1999) (53)
- Disulfide Bond Engineering to Trap Peptides in the MHC Class I Binding Groove1 (2007) (53)
- Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes (2019) (52)
- Structural engineering of pMHC reagents for T cell vaccines and diagnostics. (2007) (52)
- The role of mhc polymorphism in anti-microbial resistance. (2004) (50)
- Structural Basis of Cytochrome c Presentation by IEk (2002) (50)
- An unusual Fc receptor-related protein expressed in human centroblasts (2002) (50)
- Natural killer cell‐mediated lysis of dorsal root ganglia neurons via RAE1/NKG2D interactions (2003) (49)
- Subversion of cytokine networks by virally encoded decoy receptors (2012) (49)
- Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor (2007) (49)
- Structural analysis of MHC class I molecules with bound peptide antigens. (1993) (49)
- A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters (2021) (46)
- Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in Mice (2018) (46)
- Potent Dengue Virus Neutralization by a Therapeutic Antibody with Low Monovalent Affinity Requires Bivalent Engagement (2014) (45)
- Myeloid skewing in murine autoimmune arthritis occurs in hematopoietic stem and primitive progenitor cells. (2012) (45)
- Human C-type Lectin Domain Family 4, Member C (CLEC4C/BDCA-2/CD303) Is a Receptor for Asialo-galactosyl-oligosaccharides* (2011) (44)
- Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming (2012) (44)
- Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans (2020) (43)
- Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy (2016) (43)
- A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques (2021) (41)
- LDLRAD3 is a receptor for Venezuelan equine encephalitis virus (2020) (41)
- Dual engagement regulation of protein interactions with the AP-2 adaptor alpha appendage. (2004) (41)
- Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity (2019) (40)
- Structural Determinants of Chemokine Binding by an Ectromelia Virus-Encoded Decoy Receptor (2006) (40)
- Tumour necrosis factor superfamily cytokines and the pathogenesis of inflammatory osteolysis (2002) (40)
- Recognition of open conformers of classical MHC by chaperones and monoclonal antibodies (2005) (38)
- Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses (2018) (37)
- A molecular understanding of alphavirus entry (2020) (36)
- Correlating RANK Ligand/RANK Binding Kinetics With Osteoclast Formation and Function (2015) (36)
- Structural Determinants of Herpesvirus Entry Mediator Recognition by Murine B and T Lymphocyte Attenuator1 (2008) (36)
- T cell receptor (TCR) recognition of MHC class I variants: intermolecular second-site reversion provides evidence for peptide/MHC conformational variation (1996) (35)
- X-ray crystallographic analysis of free and antigen-complexed Fab fragments to investigate structural basis of immune recognition. (1991) (35)
- Altered compensatory cytokine signaling underlies the discrepancy between Flt3–/– and Flt3l–/– mice (2018) (34)
- Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein (2018) (34)
- Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature. (2012) (33)
- Structural Mechanism of ER Retrieval of MHC Class I by Cowpox (2012) (33)
- Crystallization of murine major histocompatibility complex class I H-2Kb with single peptides. (1992) (32)
- Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily (2015) (32)
- Structural Definition of the H-2Kd Peptide-binding Motif* (2006) (32)
- Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion (2019) (31)
- Basic and translational applications of engineered MHC class I proteins. (2010) (31)
- Structural aspects of antibodies and antibody-antigen complexes. (2007) (30)
- Cutting Edge: FcR-Like 5 on Innate B Cells Is Targeted by a Poxvirus MHC Class I-Like Immunoevasin (2010) (29)
- Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective. (2020) (29)
- Structure of the St. Louis Encephalitis Virus Postfusion Envelope Trimer (2012) (28)
- A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion (2017) (27)
- Identification and Sequencing of a Novel Rodent Gammaherpesvirus That Establishes Acute and Latent Infection in Laboratory Mice (2011) (26)
- Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge (2019) (26)
- Preparation of Stable Single‐Chain Trimers Engineered with Peptide, β2 Microglobulin, and MHC Heavy Chain (2009) (25)
- Mutations changing the kinetics of class II MHC peptide exchange. (2001) (24)
- T-Cell Tolerance for Variability in an HLA Class I-Presented Influenza A Virus Epitope (2009) (24)
- Human Major Histocompatibility Complex (MHC) Class I Molecules with Disulfide Traps Secure Disease-related Antigenic Peptides and Exclude Competitor Peptides* (2008) (24)
- Crystal Structure of the Cowpox Virus-Encoded NKG2D Ligand OMCP (2012) (23)
- Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus (2018) (23)
- Structure, Expression, and Intracellular Localization of the SARS-CoV Accessory Proteins 7a and 7b (2006) (22)
- An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. (2020) (21)
- A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy (2019) (20)
- Peptide selection by an MHC H-2Kb class I molecule devoid of the central anchor ("C") pocket. (1998) (20)
- Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution (2004) (20)
- Distinct B cell subsets give rise to antigen-specific antibody responses against SARS-CoV-2 (2020) (19)
- Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy (2020) (19)
- Molluscum contagiosum virus MC80 sabotages MHC-I antigen presentation by targeting tapasin for ER-associated degradation (2019) (19)
- The Fc Region of an Antibody Impacts the Neutralization of West Nile Viruses in Different Maturation States (2013) (18)
- Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis (2020) (18)
- The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1. (2013) (18)
- Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors. (2016) (18)
- The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies (2021) (17)
- Rodent Herpesvirus Peru Encodes a Secreted Chemokine Decoy Receptor (2013) (17)
- Oxidative refolding from inclusion bodies. (2014) (17)
- Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope (2021) (17)
- Seroprevalence of SARS-CoV-2 Antibodies in Children and Adults in St. Louis, Missouri, USA (2021) (17)
- Dual role of endothelial Myct1 in tumor angiogenesis and tumor immunity (2021) (17)
- SARS-CoV-2 Infection Severity Is Linked to Superior Humoral Immunity against the Spike (2021) (16)
- Cowpox virus employs a two-pronged strategy to outflank MHCI antigen presentation. (2013) (16)
- A Library of Infectious Hepatitis C Viruses with Engineered Mutations in the E2 Gene Reveals Growth-Adaptive Mutations That Modulate Interactions with Scavenger Receptor Class B Type I (2016) (15)
- Functional Evidence That Conserved TCR CDRα3 Loop Docking Governs the Cross-Recognition of Closely Related Peptide:Class I Complexes1 (2001) (15)
- Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses (2021) (15)
- Identification of somatic JAK 1 mutations in patients with acute myeloid leukemia (2008) (14)
- Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice (2019) (14)
- Polyclonal epitope mapping reveals temporal dynamics and diversity of human antibody responses to H5N1 vaccination (2021) (14)
- Cross-priming induces immunodomination in the presence of viral MHC class I inhibition (2018) (12)
- A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope (2021) (11)
- Manipulation of receptor oligomerization as a strategy to inhibit signaling by TNF superfamily members (2014) (11)
- STRUCTURE OF THE SARS-CoV-2 ORF7A ENCODED ACCESSORY PROTEIN (2020) (10)
- Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD (2021) (10)
- Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor (2021) (9)
- Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation (2019) (8)
- A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis. (2021) (8)
- Targeting of IL-2 to cytotoxic lymphocytes as an improved method of cytokine-driven immunotherapy (2017) (7)
- Antigen-specific depletion of CD4+ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity (2022) (7)
- Antibody-mediated immunity to SARS-CoV-2 spike (2022) (7)
- MMTV Superantigens Coerce an Unconventional Topology between the TCR and MHC Class II (2014) (7)
- Potent neutralization of Rift Valley fever virus by human monoclonal antibodies through fusion inhibition (2021) (7)
- Immune recognition of viral antigens. (1994) (7)
- MR1 antigen presentation to mucosal-associated invariant T cells is highly conserved in mammals (78.7) (2009) (6)
- Improved integration of single-cell transcriptome and surface protein expression by LinQ-View (2021) (6)
- mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes (2022) (6)
- Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunity. (2021) (5)
- Complex phenotypes in mosquitoes and mice associated with neutralization escape of a Dengue virus type 1 monoclonal antibody. (2012) (5)
- Minecraftr on Demand – A new IGN service which combines game and 3D cartography (2018) (5)
- A single intranasal dose of chimpanzee adenovirus-vectored vaccine confers sterilizing immunity against SARS-CoV-2 infection (2020) (5)
- A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement (2018) (4)
- Progression of SARS-CoV-2 Seroprevalence in St. Louis, Missouri, through January 2021 (2021) (3)
- Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain (2021) (3)
- Isolation of a Potently Neutralizing and Protective Human Monoclonal Antibody Targeting Yellow Fever Virus (2022) (3)
- Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors (2020) (3)
- Eukaryotic expression systems for structural studies. (2014) (3)
- CD300LF Polymorphisms of Inbred Mouse Strains Confer Resistance to Murine Norovirus Infection in a Cell Type-Dependent Manner (2020) (3)
- RANKL employs distinct binding modes to engage RANK and the OPG decoy receptor (2013) (2)
- Structural characterization of broadly neutralizing alphavirus antibodies (2018) (2)
- STRUCTURE OF THE SARS-CoV-2 ORF8 ENCODED ACCESSORY PROTEIN (2020) (2)
- tyrosine kinase genes of patients with de novo acute myeloid leukemia Somatic mutations and germline sequence variants in the expressed (2013) (2)
- Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D (2014) (1)
- The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors (2022) (1)
- Structural basis of cowpox evasion of NKG2D immunosurveillance (2019) (1)
- Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA (2022) (1)
- Crystal structure of hemagglutinin from influenza virus A/Pennsylvania/14/2010 (H3N2) (2019) (1)
- Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein (2018) (1)
- Target selection for structural genomics of infectious diseases. (2014) (1)
- mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in patients with antibody deficiency syndromes (2022) (1)
- Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor (2019) (1)
- CRYSTAL STRUCTURE OF THE EPSIN N-TERMINAL HOMOLOGY (ENTH) DOMAIN AT 1.56 ANGSTROM RESOLUTION (2000) (1)
- Structural basis of neutralization of Powassan virus by monoclonal antibodies (2020) (1)
- Ligands for murine NKG2D display heterogeneous binding behavior (2002) (1)
- current as Distinct MHC Molecules by a Single TCR Arthritic Peptide and a Foreign Epitope on Molecular Basis for Recognition of an Fremont and (2000) (1)
- Crystal Structure of Von Willebrand Factor (VWF) A1 Domain in Complex with Aptamer ARC1172, An Inhibitor of VWF-Platelet Binding (2009) (1)
- Altering a Peptide MHC Anchor Residue Structural and Functional Consequences of (2001) (1)
- Biochemical Features of the MHC-Related (2003) (1)
- Ebola images emerge from the cave. (2008) (1)
- Health Care Associated Outbreak of SARS CoV2 in a Rural Hospital - Missouri, March 2020. (2020) (1)
- Polyclonal epitope cartography reveals the temporal dynamics and diversity of human antibody responses to H5N1 vaccination (2020) (1)
- Hydrogen-deuterium exchange mass spectrometry identifies spatially distinct antibody epitopes on domain III of the Zika virus envelope protein. (2020) (1)
- CRYSTAL STRUCTURE OF TRANCE/RANKL CYTOKINE. (2001) (1)
- Induction of Epitope-Specific Neutralizing Antibodies against (2007) (1)
- Crystal Structure of the Lectin Domain From the F17-like Adhesin, UclD (2017) (0)
- Structure of Cowpox CPXV203 in complex with MHCI (H-2Kb) (2012) (0)
- Zbtb46 coordinates angiogenesis and immunity to control tumor outcome (2023) (0)
- STRUCTURE OF THE SARS-CORONAVIRUS ORF7A ACCESSORY PROTEIN (2004) (0)
- Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and Herpies Simplex Virus Mutant Glycoprotein B Peptide (2004) (0)
- THE AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE IN COMPLEX WITH AMPHIPHYSIN FXDXF (2002) (0)
- LDLRAD3 is a receptor for Venezuelan equine encephalitis virus (2020) (0)
- CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE (2002) (0)
- HIP1R THATCH DOMAIN CORE (2004) (0)
- Crystal structure of hemagglutinin from influenza virus A/Phillipines/2/1982 (H3N2) (2019) (0)
- Crystal structure of Fab 1A1D-2 complexed with E-DIII of Dengue virus at 3.8 angstrom resolution (2007) (0)
- Mxra8 is a receptor for multiple arthritogenic alphaviruses (2018) (0)
- Positive‐strand RNA viruses—a Keystone Symposia report (2023) (0)
- Identification and Sequencing of a Novel Rodent Gammaherpesvirus That Establishes Acute and Latent Infection in Laboratory Mice (cid:1) (2011) (0)
- Crystal Structure of the Japanese Encephalitis Virus Envelope Protein, strain SA-14-14-2. (2010) (0)
- Poxvirus subversion of B7-mediated T cell co-stimulation (2018) (0)
- Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid (2018) (0)
- West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab (2005) (0)
- Crystal structure of viral chemokine binding protein R17 in complex with CCL3 (2015) (0)
- Crystal Structure of Murine CD300lf in complex with phosphocholine (2018) (0)
- Characterization of a novel dengue virus strain and its implication for vaccine development (2020) (0)
- Mucosal-Associated Invariant T Cells Membrane in a Conformation That Activates Transiently Expressed on the Plasma Endogenous MHC-Related Protein 1 Is Diamond and (2011) (0)
- University of Groningen Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus Pal, (2013) (0)
- Development of a computational model to quantify antigenic similarity between Dengue viruses (2018) (0)
- Crystal structure of hemagglutinin from influenza virus A/Sichuan/2/1987 (H3N2) (2020) (0)
- The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53 (2009) (0)
- Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80 (2021) (0)
- Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B Peptide (2004) (0)
- SARS-CoV-2 Spike in complex with neutralizing Fab 2B04 (one up, two down conformation) (2021) (0)
- OHP-025 Investigations following increasing complaints about infusion sets for safe administration of cytostatics (2015) (0)
- Antigen-guided depletion of anti-HLA antibody-producing cells by HLA-Fc fusion proteins. (2022) (0)
- VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS68 IN COMPLEX WITH THE P8A VARIANT OF CC-CHEMOKINE MCP-1 (2002) (0)
- Zika specific antibody, ZV-48, bound to ZIKA envelope DIII (2016) (0)
- Protection Against Influenza B Viruses by Human Monoclonal Antibodies that Target the Neuraminidase Active Site (2020) (0)
- HISTOCOMPATIBILITY ANTIGEN I-AG7 (1998) (0)
- SARS-CoV-2 Spike RBD in complex with neutralizing Fab SARS2-38 (local refinement) (2021) (0)
- Integration of Transcriptome and Cell Surface Protein Expression by LinQ-View Identifies Unique Immune Subpopulations (2021) (0)
- Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013 (2020) (0)
- Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor (2018) (0)
- Healthcare-associated outbreak of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in a rural hospital in Missouri, March 2020 (2020) (0)
- Translational and basic applications of peptide-MHCI single chain trimers (2010) (0)
- In This Issue (2006) (0)
- Crystal structure of DENV1-E111 single chain variable fragment bound to DENV-1 DIII, strain 16007. (2012) (0)
- Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013 (2020) (0)
- Mhc Class I Natural H-2Kb Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Mutant Glycoprotein B Peptide (2004) (0)
- Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography (2007) (0)
- Structural basis of MHCI antigen presentation sabotage by cowpox CPXV203 (2012) (0)
- MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND YEAST ALPHA-GLUCOSIDASE (1996) (0)
- MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND SENDAI VIRUS NUCLEOPROTEIN (1996) (0)
- The structure of cowpox virus CPXV018 (OMCP) (2012) (0)
- Antigen processing and presentation (PP-026) (2010) (0)
- Antibody Recognition of Cell Surface-Associated NS1 Triggers Fc- (cid:2) Receptor-Mediated Phagocytosis and Clearance of West Nile Virus-Infected Cells (cid:1) (2007) (0)
- STRUCTURE OF THE BTLA ECTODOMAIN (2004) (0)
- MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN (1996) (0)
- Use of CART cells to selectively target autoantigen-specific T cells for the treatment of autoimmune diabetes (2020) (0)
- Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C, beta-2microglobulin, and ovalbumin-derived peptide. (2007) (0)
- COVID-19 Infection Induces Substantial Memory B Cell Maturation to Non-Neutralizing Viral Targets (2021) (0)
- SARS-CoV-2 Spike in complex with neutralizing Fab SARS2-38 (three down conformation) (2021) (0)
- Function Protein 1 Consistent with an Immunological Biochemical Features of the MHC-Related Lonnie (2003) (0)
- Identification of Novel, Non-Synonymous Sequence Changes in the Tyrosine Kinase Genes of Patients with Acute Myeloid Leukemia. (2007) (0)
- Toxoplasma Gondii Actin Assembles via Isodesmic Polymerization (2013) (0)
- Structural and Antigenic Features of Powassan Virus Envelope Protein (2018) (0)
- Release Evolutionary Conserved Design to Inhibit BST-2 / Tetherin Ectodomains Reveals an Structural and Biophysical Analysis of Immunology : (2011) (0)
- C1q Reduces the Stoichiometric Threshold for Antibody-Mediated Neutralization of West Nile Virus (2009) (0)
- Crystal Structure of Swine Flu Virus NS1 Effector Domain from H1N1 Influenza A/California/07/2009 (2010) (0)
- Crystal structure of hemagglutinin from influenza virus A/Texas/1/1977 (H3N2) (2019) (0)
- Structural immunology of mouse MHC class 1 (1993) (0)
- Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The CC-Chemokine CCL2/MCP-1 (2007) (0)
- Structural basis of MHCI antigen presentation sabotage by cowpox encoded protein CPXV203 (168.18) (2012) (0)
- MHC Class I H-2Kd heavy chain in complex with beta-2microglobulin and peptide derived from influenza nucleoprotein (2006) (0)
- to a T Cell Hybridoma Covalently Linked Peptides: Specific Binding 2-Microglobulin β Soluble Class I MHC with (2013) (0)
- Crystal Structure of mouse RANK bound to RANKL (2012) (0)
- Antigen-specific MAIT cell subsets involved in TB immunity (INC2P.420) (2015) (0)
- Crystal structure of hemagglutinin from influenza virus A/Netherlands/209/1980 (H3N2) (2019) (0)
- Crystal structure of an H-2 Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove ( murine major histocompatibility complex class I / allele-specific motifs / x-ray crystallography ) (2005) (0)
- Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain). (2012) (0)
- by binding the regulatory protein factor H From the Cover : West Nile virus nonstructural protein NS 1 inhibits complement activation (2006) (0)
- CLM-1 Mouse Myeloid Receptor Extracellular Domain (2005) (0)
- Crystal structure of ZIKV-116 Fab in complex with ZIKV envelope DIII (2019) (0)
- Structure of the St. Louis Encephalitis Virus envelope protein in the fusogenic trimer conformation. (2012) (0)
- Crystal Structure of a single chain trimer composed of the MHC I heavy chain H-2Kb Y84A, beta-2microglobulin, and ovalbumin-derived peptide. (2007) (0)
- Specific for Riboflavin Metabolites Mucosal-Associated Invariant T Cells Antimycobacterial Effects of Mouse Functional Heterogeneity and (2015) (0)
- Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII (2013) (0)
- CryoEM structure of Venezuelan equine encephalitis virus VLP (2021) (0)
- MURINE CYTOMEGALOVIRUS IMMUNOMODULATORY PROTEIN M144 (2004) (0)
- ImmunoevasinIs Targeted by a Poxvirus MHC Class I-Like Cutting Edge: FcR-Like 5 on Innate B Cells (2010) (0)
- and T Lymphocyte Attenuator Entry Mediator Recognition by Murine B Structural Determinants of Herpesvirus (2007) (0)
- SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response in primary antibody deficiency patients (2022) (0)
- MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND CHICKEN OVALBUMIN (1996) (0)
- Crystal Structure of Bos taurus Mxra8 Ectodomain (2020) (0)
- Crystal structure analysis of dengue-1 envelope protein domain III (2008) (0)
- VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS 68 (2002) (0)
- AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE IN COMPLEX WITH EPS15 DPF PEPTIDE (2002) (0)
- Molluscum contagiosum virus subverts MHC-I antigen presentation by targeting tapasin for degradation (2018) (0)
- West Nile Virus NS1 in complex with neutralizing 22NS1 antibody Fab (2014) (0)
- Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Glycochenodeoxycholic Acid (2018) (0)
- CryoEM structure of Venezuelan equine encephalitis virus VLP in complex with the LDLRAD3 receptor (2021) (0)
- Crystal structure of murine Mxra8 ectodomain (2019) (0)
- PocketMolecule Devoid of the Central Anchor (''C'') Class I b Peptide Selection by an MHC H-2K (1998) (0)
- leukemia Identification of somatic JAK1 mutations in patients with acute myeloid (2013) (0)
- CRYSTAL STRUCTURE OF THE AP-2 CLATHRIN ADAPTOR ALPHA-APPENDAGE (1999) (0)
- West Nile Virus Non-structural Protein NS1 (2014) (0)
- Structural studies of West Nile virus in complex with neutralizing antibodies (2008) (0)
- Viral chemokine binding protein R17 encoded by rodent gammaherpesvirus Peru ( RHVP) (2015) (0)
- Mhc Class I H-2Kb Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B peptide (2004) (0)
- Crystal structure of ectromelia virus EVM1 chemokine binding protein (2006) (0)
- Crystal structure of mouse RANKL-OPG complex (2012) (0)
- Electron Cryo-Microscopy Of Chikungunya VLP (2019) (0)
- Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron Variants in Mice and Hamsters (2023) (0)
- Herpesvirus Entry Mediator and Cytomegalovirus ORF UL144 bind a common region of B and T Lymphocyte Attenuator (2007) (0)
- Crystal structure of phospholipase A 2 from Indian cobra reveals a trimeric association ( x-ray crystallography / protein structure / protein trimer / nolecular replacement ) (0)
- Mechanisms of Zika virus antibody neutralization (2018) (0)
- Crystal structure of mouse CD300lf at 1.6 Angstroms resolution. (2016) (0)
- Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor (2019) (0)
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