David. A. Gewirtz

David. A. Gewirtz's AcademicInfluence.com Rankings

David. A. Gewirtz

Philosophy

#7293

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#10485

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#4349

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#5632

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philosophy Degrees

David. A. Gewirtz

Biology

#9892

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#13154

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Molecular Biology

#1389

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#1416

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Philosophy
Biology

David. A. Gewirtz's Degrees

PhD Molecular Biology University of California, Berkeley
Doctorate Medicine Stanford University

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David. A. Gewirtz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. (1999) (2059)
Molecular definitions of autophagy and related processes (2017) (1036)
Autophagy in malignant transformation and cancer progression (2015) (941)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells. (1994) (447)
Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. (1994) (438)
The four faces of autophagy: implications for cancer therapy. (2014) (348)
Autophagy in major human diseases (2021) (282)
Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation. (2008) (276)
Adriamycin-induced Senescence in Breast Tumor Cells Involves Functional p53 and Telomere Dysfunction* (2002) (263)
A comprehensive glossary of autophagy-related molecules and processes (2nd edition) (2011) (259)
A comprehensive glossary of autophagy-related molecules and processes (2010) (253)
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells. (1994) (175)
Rapid catabolism of 5-fluorouracil in freshly isolated rat hepatocytes as analyzed by high performance liquid chromatography. (1982) (142)
p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells (2005) (134)
Therapy-Induced Senescence: An “Old” Friend Becomes the Enemy (2020) (134)
Dual functions of autophagy in the response of breast tumor cells to radiation (2012) (132)
Evasion of a Single-Step, Chemotherapy-Induced Senescence in Breast Cancer Cells: Implications for Treatment Response (2005) (131)
Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy. (2019) (129)
Autophagy, senescence and tumor dormancy in cancer therapy (2009) (126)
Autophagy and senescence (2013) (121)
Cytotoxic Autophagy in Cancer Therapy (2014) (115)
The Autophagy-Senescence Connection in Chemotherapy: Must Tumor Cells (Self) Eat Before They Sleep? (2012) (115)
Autophagy and Senescence in Cancer Therapy (2013) (106)
A Switch Between Cytoprotective and Cytotoxic Autophagy in the Radiosensitization of Breast Tumor Cells by Chloroquine and Vitamin D (2011) (103)
Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA. (1992) (100)
Autophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy? (2013) (98)
The combination of a potent vitamin D3 analog, EB 1089, with ionizing radiation reduces tumor growth and induces apoptosis of MCF-7 breast tumor xenografts in nude mice. (2003) (95)
Promotion of autophagy as a mechanism for radiation sensitization of breast tumor cells. (2009) (94)
Tumor cell escape from therapy‐induced senescence (2019) (93)
Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells. (1994) (90)
Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin. (1994) (89)
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy (2021) (86)
Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer (2014) (84)
Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery (2006) (82)
Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin. (2009) (81)
Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse (2017) (80)
A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089 (2014) (77)
Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin. (1996) (76)
Is Senescence Reversible? (2016) (76)
HIV-1 and Morphine Regulation of Autophagy in Microglia: Limited Interactions in the Context of HIV-1 Infection and Opioid Abuse (2014) (75)
The vitamin D3 analog EB 1089 enhances the antiproliferative and apoptotic effects of adriamycin in MCF-7 breast tumor cells (2000) (73)
Growth arrest and cell death in the breast tumor cell in response to ionizing radiation and chemotherapeutic agents which induce DNA damage (2000) (73)
Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison. (2007) (73)
The vitamin D3 analog EB 1089 enhances the response of human breast tumor cells to radiation. (1999) (69)
The vitamin D3 analog, ILX-23-7553, enhances the response to Adriamycin and irradiation in MCF-7 breast tumor cells (2001) (69)
Clearance of therapy‐induced senescent tumor cells by the senolytic ABT‐263 via interference with BCL‐XL–BAX interaction (2020) (63)
An accelerated senescence response to radiation in wild-type p53 glioblastoma multiforme cells. (2006) (61)
Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells (2016) (61)
Influence of the phosphodiesterase-5 inhibitor, sildenafil, on sensitivity to chemotherapy in breast tumor cells (2010) (59)
Erythropoietin Fails to Interfere with the Antiproliferative and Cytotoxic Effects of Antitumor Drugs (2006) (54)
Formation of methotrexate polyglutamates in rat hepatocytes. (1979) (54)
Cytoprotective and nonprotective autophagy in cancer therapy (2013) (54)
Cytotoxicity, DNA strand breakage and DNA-protein crosslinking by a novel transplatinum compound in human A2780 ovarian and MCF-7 breast carcinoma cells. (2004) (54)
Does bulk damage to DNA explain the cytostatic and cytotoxic effects of topoisomerase II inhibitors? (1991) (53)
Transport, binding, and polyglutamation of methotrexate in freshly isolated rat hepatocytes. (1980) (52)
Non-Cell Autonomous Effects of the Senescence-Associated Secretory Phenotype in Cancer Therapy (2018) (52)
The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy. (2016) (50)
Influence of p53 and caspase 3 activity on cell death and senescence in response to methotrexate in the breast tumor cell. (2004) (49)
Yet Another Function of p53—The Switch That Determines Whether Radiation-Induced Autophagy Will Be Cytoprotective or Nonprotective: Implications for Autophagy Inhibition as a Therapeutic Strategy (2015) (46)
Senolytics for Cancer Therapy: Is All that Glitters Really Gold? (2021) (45)
Comparative Cardiac Toxicity of Anthracyclines In Vitro and In Vivo in the Mouse (2013) (45)
Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy (2018) (45)
Anibamine, a natural product CCR5 antagonist, as a novel lead for the development of anti-prostate cancer agents. (2010) (44)
An autophagic switch in the response of tumor cells to radiation and chemotherapy. (2014) (44)
Toxicity issues in cancer drug development. (2010) (44)
Young plasma reverses age‐dependent alterations in hepatic function through the restoration of autophagy (2017) (44)
Photocaged permeability: a new strategy for controlled drug release. (2012) (43)
Docking and hydropathic scoring of polysubstituted pyrrole compounds with antitubulin activity. (2008) (43)
A chemotherapy-associated senescence bystander effect in breast cancer cells (2008) (42)
Influence of ionizing radiation on proliferation, c-myc expression and the induction of apoptotic cell death in two breast tumour cell lines differing in p53 status. (1997) (42)
Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy (2018) (37)
Effect of the vitamin D3 analog ILX 23-7553 on apoptosis and sensitivity to fractionated radiation in breast tumor cells and normal human fibroblasts (2003) (36)
The Autophagic Response to Radiation: Relevance for Radiation Sensitization in Cancer Therapy (2014) (36)
Some considerations in the experimental approach to distinguishing between membrane transport and intracellular disposition of antineoplastic agents, with specific reference to fluorodeoxyuridine, actinomycin D, and methotrexate. (1981) (34)
Antagonism between tamoxifen and doxorubicin in the MCF-7 human breast tumor cell line. (1994) (33)
Characterization of a K562 multidrug-resistant cell line. (1989) (33)
The Roles of Autophagy and Senescence in the Tumor Cell Response to Radiation (2020) (33)
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein (2005) (32)
Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089 (2004) (32)
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
A mouse model of radiation-induced cardiomyopathy. (2012) (29)
Metabolism of adriamycin in hepatocytes isolated from the rat and the rabbit. (1987) (29)
Triangular Relationship between p53, Autophagy, and Chemotherapy Resistance (2020) (29)
Evidence for inhibition of growth related to compromised DNA synthesis in the interaction of daunorubicin with H-35 rat hepatoma. (1988) (29)
Role of Interleukin-1 in Radiation-Induced Cardiomyopathy (2015) (28)
Influence of amsacrine (m-AMSA) on bulk and gene-specific DNA damage and c-myc expression in MCF-7 breast tumor cells. (1994) (28)
The lysosome as an imperative regulator of autophagy and cell death (2021) (27)
Potent bile salt and organic anion inhibition of methotrexate uptake and accumulation in the freshly isolated rat hepatocyte. (1980) (27)
Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14 (2013) (27)
When cytoprotective autophagy isn’t… and even when it is (2014) (27)
Colchicine site inhibitors of microtubule integrity as vascular disrupting agents (2008) (27)
Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN (2018) (26)
Apoptosis, senescence, and cancer (2007) (26)
Importance of Autophagy in Mediating Human Immunodeficiency Virus (HIV) and Morphine-Induced Metabolic Dysfunction and Inflammation in Human Astrocytes (2017) (26)
Ionizing radiation-induced DNA strand breakage and rejoining in specific genomic regions as determined by an alkaline unwinding/Southern blotting method. (1995) (26)
Combined Antiproliferative Effects of the Aminoalkylindole WIN55,212-2 and Radiation in Breast Cancer Cells (2014) (26)
Induction of DNA damage, inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog, idarubicin (4-demethoxy-daunorubicin) in the MCF-7 breast tumor cell line (1998) (26)
Roles of autophagy in breast cancer treatment: target, bystander or benefactor. (2019) (25)
Autophagy as a Mechanism of Radiation Sensitization in Breast Tumor Cells (2007) (25)
Promotion of DNA strand breaks, interstrand cross-links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes. (2007) (25)
Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer. (2016) (24)
Tumor Cell Recovery from Senescence Induced by Radiation with PARP Inhibition (2016) (23)
Modulation of 5-fluorouracil catabolism in isolated rat hepatocytes with enhancement of 5-fluorouracil glucuronide formation. (1985) (23)
Dissociation between bulk damage to DNA and the antiproliferative activity of teniposide (VM-26) in the MCF-7 breast tumor cell line: evidence for induction of gene-specific damage and alterations in gene expression. (1993) (22)
A non-calcemic sulfone version of the vitamin D(3) analogue seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin. (2001) (22)
The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal (2019) (22)
Induction of Taurocholate Release from Isolated Rat Hepatocytes in Suspension by α‐Adrenergie Agents and Vasopressin: Implications for Control of Bile Salt Secretion (1984) (21)
Differential Radiation Sensitivity in p53 Wild-Type and p53-Deficient Tumor Cells Associated with Senescence but not Apoptosis or (Nonprotective) Autophagy (2018) (21)
Effect of pharmacologically relevant concentrations of mitoxantrone on the in vitro growth of leukemic blast progenitors. (1991) (21)
Targeting tumor cell senescence and polyploidy as potential therapeutic strategies. (2020) (21)
Effects of Tamoxifen on the Radiosensitivity of Hormonally Responsive and Unresponsive Breast Carcinoma Cells (1993) (19)
Stimulation of taurocholate and glycocholate efflux from the rat hepatocyte by arginine vasopressin. (1988) (19)
Interference with endothelial cell function by JG-03-14, an agent that binds to the colchicine site on microtubules. (2009) (19)
Autophagy and radiosensitization in cancer (2014) (19)
Sustained enhancement of liposome-mediated gene delivery and gene expression in human breast tumour cells by ionizing radiation. (1999) (18)
Suppression of c-myc expression and c-Myc function in response to sustained DNA damage in MCF-7 breast tumor cells. (2001) (17)
Modulation of transplanaramine platinum complex reactivity by systematic modification of carrier and leaving groups (2009) (17)
Vitamin D3 and vitamin D3 analogues as an adjunct to cancer chemo-therapy and radiotherapy. (2002) (17)
Interaction of probenecid with methotrexate transport and release in the isolated rat hepatocyte in suspension. (1984) (17)
The natural product CCR5 antagonist anibamine and its analogs as anti-prostate cancer agents. (2011) (16)
QW-1624F2-2, a synthetic analogue of 1,25-dihydroxyvitamin D3, enhances the response to other deltanoids and suppresses the invasiveness of human metastatic breast tumor cells (2006) (15)
Targeting Peroxisome Proliferator-Activated Receptor-α (PPAR- α) to reduce paclitaxel-induced peripheral neuropathy (2021) (15)
A combined alkaline unwinding/Southern blotting assay for measuring low levels of cellular DNA breakage within specific genomic regions. (1992) (15)
The Influence of Nicotine on Lung Tumor Growth, Cancer Chemotherapy, and Chemotherapy-Induced Peripheral Neuropathy (2018) (15)
Young plasma attenuates age‐dependent liver ischemia reperfusion injury (2018) (14)
Accelerated partial-breast irradiation: trial by media or by science? (2012) (14)
Influence of nonprotective autophagy and the autophagic switch on sensitivity to cisplatin in non-small cell lung cancer cells. (2020) (14)
Biochemical lesions in DNA associated with the antiproliferative effects of mitoxantrone in the hepatoma cell. (1990) (14)
Metabolism of the anthracycline antibiotic daunorubicin to daunorubicinol and deoxydaunorubicinol aglycone in hepatocytes isolated from the rat and the rabbit. (1986) (14)
Induction of DNA damage, inhibition of DNA synthesis, and suppression of c-myc expression by the topoisomerase I inhibitor, camptothecin, in MCF-7 human breast tumor cells. (1998) (13)
Efflux in isolated hepatocytes as a possible correlate of secretion in vivo: induced exit of the folic acid analog methotrexate, by dibutyryl cyclic AMP or isobutyl methyl xanthine. (1981) (13)
Estradiol enhances gene delivery to human breast tumor cells (1998) (13)
Autophagy, senescence, and apoptosis. (2013) (13)
Evidence from rat hepatocytes of an unrecognized pathway of 5-fluorouracil metabolism with the formation of a glucuronide derivative. (1985) (13)
Proteomics Insights into Autophagy (2017) (12)
Characteristics of the formation and membrane transport of 7-hydroxymethotrexate in freshly isolated rabbit hepatocytes. (1985) (12)
Influence of topoisomerase II inhibitors and ionizing radiation on growth arrest and cell death pathways in the breast tumor cell (2007) (12)
Enhancement of radiation sensitivity, delay of proliferative recovery after radiation and abrogation of MAPK (p44/42) signaling by imatinib in glioblastoma cells. (2006) (11)
Radiosensitization of HL-60 human leukaemia cells by bryostatin-1 in the absence of increased DNA fragmentation or apoptotic cell death. (1996) (11)
The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer (2020) (11)
DNA damage, gene expression, growth arrest and cell death. (1993) (11)
Ionizing radiation and teniposide increase p21(waf1/cip1) and promote Rb dephosphorylation but fail to suppress E2F activity in MCF-7 breast tumor cells. (1997) (10)
Is Autophagy Always a Barrier to Cisplatin Therapy? (2022) (10)
Androgen-deprivation induced senescence in prostate cancer cells is permissive for the development of castration-resistance but susceptible to senolytic therapy. (2021) (10)
Catecholamine-induced release of the folic acid analogue, methotrexate, from rat hepatocytes in suspension. An alpha-adrenergic phenomenon. (1982) (10)
Estradiol enhances liposome-mediated uptake, preferential nuclear accumulation and functional expression of exogenous genes in MDA-MB231 breast tumor cells. (1999) (10)
Considering therapy-induced senescence as a mechanism of tumour dormancy contributing to disease recurrence (2022) (10)
Abstract 4652: The autophagy-senescence connection in chemotherapy of breast tumor cells; senescence accelerated by autophagy but not dependent on autophagy (2012) (9)
Enhanced sensitivity of the rat hepatoma cell to the daunorubicin analogue 4-demethoxydaunorubicin associated with induction of DNA damage. (1989) (9)
Enhancement of liposomal gene delivery in human breast cancer cells by dimethyl sulfoxide. (1998) (9)
Senescence and castration resistance in prostate cancer: A review of experimental evidence and clinical implications. (2020) (8)
The potentially conflicting cell autonomous and cell non‐autonomous functions of autophagy in mediating tumor response to cancer therapy (2018) (8)
Apoptosis as the predominant tumor cell response to chemotherapy and irradiation: a case of TUNEL vision? (2005) (8)
Transcriptional down-regulation of c-myc expression in the MCF-7 breast tumor cell line by the topoisomerase II inhibitor, VM-26. (1995) (8)
Protein binding as a component of drug interaction in cellular pharmacokinetic studies. Effects of probenecid on transport and accumulation of methotrexate in Ehrlich ascites tumor cells in vitro. (1985) (8)
Receptor-mediated stimulation of taurocholate efflux from the rat hepatocyte and the ex vivo perfused rat liver. (1990) (8)
Rb dephosphorylation and suppression of E2F activity in human breast tumor cells exposed to a pharmacological concentration of estradiol. (2001) (7)
A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice (2020) (7)
Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death. (2013) (7)
Fluvastatin Induces Apoptosis in Primary and Transformed Mast Cells (2020) (6)
Autophagy Inhibition and Chemosensitization in Cancer Therapy (2019) (6)
An overview of chemotoxicity and radiation toxicity in cancer therapy. (2022) (6)
Autophagy and senescence in cancer therapy. (2021) (5)
Reversibility of chemotherapy-induced senescence is independent of autophagy and a potential model for tumor dormancy and cancer recurrence (2017) (5)
Characteristics of the accumulation of methotrexate polyglutamate derivatives in Ehrlich ascites tumor cells and isolated rat hepatocytes. (1983) (5)
N‐acylethanolamine‐hydrolysing acid amidase: A new potential target to treat paclitaxel‐induced neuropathy (2021) (4)
The Cytoprotective, Cytotoxic and Nonprotective Functional Forms of Autophagy Induced by Microtubule Poisons in Tumor Cells—Implications for Autophagy Modulation as a Therapeutic Strategy (2022) (4)
Senolytic-Mediated Elimination of Head and Neck Tumor Cells Induced Into Senescence by Cisplatin (2021) (4)
Therapeutic Potential for Targeting Autophagy in ER+ Breast Cancer (2022) (3)
Disentangling the Mechanisms of Radiation-Induced Heart Disease in the Treatment of Breast Cancer (2015) (3)
Anibamine, a Natural Product CCR5 Antagonist, as a Novel Lead for the Development of Antiprostate Cancer Agents. (2010) (3)
Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization. (1989) (3)
Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor (2021) (3)
Abstract 2663: Dual cytoprotective and cytotoxic functions of autophagy in the response ofbreast tumor cells to radiation and in radiosensitization by vitamin D3 (2011) (2)
Abstract 17799: Role Of Interleukin-1 In Acute Radiation-induced Cardiomyopathy (2012) (2)
Application of quantitative phase imaging mass accumulation measurements to research and clinical problems in cancer (2019) (2)
Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors (2022) (2)
Autophagy, Stem Cells, and Tumor Dormancy (2014) (2)
Abstract 14774: Preserved Left Ventricular Contractile Reserve After Thoracic Irradiation in the Interleukin-1 Receptor Knock Out Mouse (2013) (2)
Loss of sphingosine kinase 2 protects against cisplatin induced-kidney injury. (2022) (2)
Abstract 3528: Induction of cytoprotective autophagy and senescence in response to chemotherapy and ionizing-radiation as possible mechanisms of tumor dormancy (2016) (1)
Abstract 902: The antiandrogen bicalutamide induces senescence in LNCaP cells and quiescence in Myc CaP cells (2019) (1)
Abstract 2385: Involvement of autophagy and senescence in DNA repair in irradiated tumor cells (2014) (1)
Abstract 998: Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy (2015) (1)
Abstract 2846: Proliferative recovery after chemotherapy-induced senescence in non-small cell lung cancer (NSCLC) cells as a model of tumor dormancy and disease recurrence (2016) (1)
The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer. (2022) (1)
Topoisomerase I poisons-induced autophagy: Cytoprotective, Cytotoxic or Non-protective. (2022) (1)
Ionizing Radiation and Teniposide Increase p 21 waf 1 / cip 1 and Promote Rb Dephosphorylation but Fail to Suppress E 2 F Activity in MCF-7 Breast Tumor Cells (1997) (1)
Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells (2021) (1)
Serum protein reduction of the enhancement of methotrexate accumulation by vincristine and 4'-demethylepipodophyllotoxin in the Ehrlich ascites tumor cell in vitro. (1985) (1)
Variable effects of tamoxifen on human hematopoietic progenitor cell growth and sensitivity to doxorubicin (2004) (1)
Evidencefrom Rat Hepatocytesof an UnrecognizedPathwayof 5-Fluorouracil Metabolismwith the Formationof a GlucuronideDerivative1 (1985) (1)
The BET inhibitor/degrader ARV-825 prolongs the growth arrest response to Fulvestrant + Palbociclib and suppresses proliferative recovery in ER-positive breast cancer (2023) (1)
Leveraging Epigenetics to Enhance the Cellular Response to Chemotherapies and Improve Tumor Immunogenicity (2018) (1)
Abstract 14880: Interleukin-18 in Radiation-induced Cardiomyopathy (2014) (1)
Abstract 1453: The cannabinoid Win55, 212-2 enhances the response of breast cancer cells to radiation (2012) (1)
Induction of methotrexate release from rat hepatocytes in suspension by alpha-adrenergic agents: involvement of calcium and metabolic energy. (1985) (1)
The role of senescence in the action of antitumor drugs. (2008) (1)
Abstract 460: Reversibility of chemotherapy-induced senescence in breast tumor cells in culture and in vivo (2018) (0)
Abstract 5665: New alternatives to photodynamic therapy based on light-enabled drug delivery. (2013) (0)
Abstract 5550: Autophagic potentiation of radiosensitization by vitamin D3 and the analog, EB1089 (2010) (0)
Hepatoma Synthesis in the Interaction of Daunorubicin with H-35 Rat Evidence for Inhibition of Growth Related to Compromised DNA Updated (2006) (0)
The Natural Product CCR5 Antagonist Anibamine and Its Analogues as Antiprostate Cancer Agents. (2012) (0)
Association with Enhanced Fragmentation of Mature DNA by the Protein Kinase C Activator Bryostatin 1 in HL-60 Cells :d-Arabinofuranosylcytosine β Potentiation of the Activity of 1-Updated (2006) (0)
Abstract 5459: Autophagy and senescence as possible mechanisms leading to proliferative recovery and escape from treatment-induced tumor dormancy (2017) (0)
Molecular basis for the accelerated senescence response to Adriamycin in MCF-7 breast and HCT-116 tumor cells (2006) (0)
Comprar Apoptosis, Senescence and Cancer | Gewirtz, David A. | 9781588295279 | Springer (2008) (0)
Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy? (2023) (0)
Vitamin D and the Risk of Cancer (2005) (0)
Investigations into the cellular mechanism of action of transplanaramines of the type trans-[Pt (O2CR)2 (L) (L’)] (2007) (0)
Senolytic Therapy: A Potential Approach for the Elimination of Oncogene-Induced Senescent HPV-Positive Cells (2022) (0)
Abstract 3299: Radiation induced p53-dependent cytoprotective autophagy fails to reduce radiation sensitivity in H460 non-small cell lung cancer cells (2017) (0)
Review article: AUTOPHAGY AND RADIOSENSITIZATION IN CANCER (2014) (0)
Abstract 2675: Radiosensitization of breast cancer cells by Vitamin D or chloroquine through modulation of the dual cytoprotective and cytotoxic functions of autophagy (2011) (0)
Knockout of fatty acid amide hydrolase (FAAH) gene attenuates cisplatin‐induced nephrotoxicity in mice (2022) (0)
Characterization of a K 562 Multidrug-resistant Cell Line 1 (2006) (0)
Abstract 1330: Role of epigenetic remodeling in sensitizing triple-negative breast cancer cells to treatment through enhanced chemotherapy-induced autophagy (2018) (0)
Treatment Induced Autophagy Associated with Tumor Dormancy and Relapse (2016) (0)
Abstract #869: Potentiation of the response to ionizing radiation in breast tumor cells by the vitamin D3 analog, EB 1089 (2009) (0)
Abstract 1326: Nonprotective autophagy fails to confer resistance to radiation (2018) (0)
Cleavage/Repair and Signal Transduction Pathways in Irradiated Breast Tumor Cells (2000) (0)
Award Number: W81XWH-06-1-0360 TITLE: Sildenafil and Phosphofiesterase-5 Inhibitors to Reduce Cardiotoxicity and Enhance the Response of Breast Tumors to Doxrubicin (2008) (0)
Abstract 993: The relationship between autophagy, senescence, and DNA repair (2015) (0)
Abstract 1329: Sensitization of non-small cell lung cancer cells (NSCLC) to radiation by Vitamin D (EB 1089) (2013) (0)
Medical Science 7 nAChR NEGATIVE ALLOSTERISM : A PROMISING APPROACH FOR COGNITIVE DISORDERS (0)
TITLE : Stimulation of Breast Tumor Cell Proliferative Recovery by the Peptide Hormone Erythropoietin PRINCIPAL INVESTIGATOR : (2006) (0)
Abstract 2024: Studying the effects of interfering with doxorubicin-induced senescence in human colon cancer HCT116 cells (2021) (0)
Abstract 459: Therapy-induced senescence is reversible in vitro and in vivo (2018) (0)
Abstract LB133: EGFR upregulation in breast cancer cells: A key mechanism of escape from antiestrogen induced death, autophagy, and senescence (2022) (0)
Analysis of 3H fluorouracil (FUra) catabolism by HPLC in freshly isolated rat hepatocytes (1982) (0)
Abstract 4114: Dual cytoprotective and cytotoxic functions of autophagy in the response of breast tumor cells to radiation and in radiosensitization by vitamin D3 (2012) (0)
Abstract 15830: ‘Out of Target’ Radiation Therapy Leads to Impaired Cardiac Contractile Reserve in the Mouse (2015) (0)
Sildenafil and Phosphodiesterase-5 Inhibitors to Reduce Cardiotoxicity and Enhance the Response of Breast Tumor Cells to Doxorubicin (2010) (0)
Abstract 1454: The role of AMPK in the radiosensitization of breast tumor cells by Vitamin D (2012) (0)
Abstract 3539: Vitamin D/EB 1089 mediated radio-sensitization of lung cancer cells and head and neck cancer cells (2016) (0)
Cellular senescence as a target to inhibit epithelial‐mesenchymal transition in HK‐2 cells (2021) (0)
Potentiation of the Activity of l-ÃŸ-o-Arabinofuranosylcytosine by the Protein Kinase C Activator Bryostatin 1 in HL-60 Cells: Association with Enhanced Fragmentation of Mature DNA1 (2006) (0)
Ionizing radiation-induced senescence of breast tumor cells is dependent on p53 and associated with telomere dysfunction. (2004) (0)
Nephrotoxicity in cancer treatment: An update. (2022) (0)
“Emerging Concepts”: New Article Category in Molecular Pharmacology (2020) (0)
Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy (2017) (0)
Abstract 602: The α7 nicotinic acetylcholine receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy without enhancing the proliferation of lung cancer cells or interfering with paclitaxel-induced antitumor activity (2018) (0)
Abstract 1465: Radiosensitization of NSCLC through modulation of autophagy and senescence (2012) (0)
Abstract 4272: Suppression of epigenetic regulator NURF leads to autophagy mediated chemo-and immune sensitization of triple negative breast cancer (2019) (0)
Editorial: Risks and Benefits of Adjuvants to Cancer Therapies (2022) (0)
Alpha adrenergic agents and vasopressin induce release (secretion) of the bile salt taurocholate from isolated rat hepatocytes in suspension (1982) (0)
Abstract 227: Mass spectrometry-based proteomics analysis of the non-small cell lung cancer secretome (2017) (0)
Abstract 3574: Nicotine prevents chemotherapy-induced peripheral neuropathy in vivo, and fails to stimulate the growth of lung cancer cells or interfere with the effectiveness of chemotherapy in vitro (2016) (0)
Elucidation of the mechanisms underlying the potentiation of cell killing by ionizing radiation in MCF-7 breast tumor cells by the vitamin D3 analog EB 1089 (2006) (0)
Preface. (2022) (0)
Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice (2023) (0)
Studies on the heat-precipitated phosphoenzyme complex of eel electric organ (Na + K).ATPase. (1979) (0)
Abstract 3957: Cell death and growth arrest pathways mediating the actions of stilbene 5C in HCT-116 colon cancer cells (2012) (0)
Fornari Induction of DNA damage , inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog (0)
Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach (2019) (0)
Involvement of the Endocannabinoid System in the Development and Treatment of Breast Cancer (2014) (0)
Abstract 1400: Mitigation of radiation-induced injury with the nitric oxide synthase co-factor, tetrahydrobiopterin (2010) (0)
Senescence in prostate cancer: is there sufficient evidence to move forward? (2021) (0)
Abstract 2848: Autophagy, senescence and proliferative recovery subsequent to DNA damage in radiation sensitization by PARP inhibition (2016) (0)
Abstract 1013: Understanding the molecular pathways underlying radio-sensitization of non-small cell lung cancer (NSCLC) by vitamin D (EB1089) (2015) (0)
Functional Characterization of the Orphan Nuclear Receptor TLX in Triple Negative Breast Cancer (2021) (0)
Stimulation of Breast Tumor Cell Proliferative Recovery by the Peptide Hormone Erythropoietin (2006) (0)
List of Referees, 2009 (2010) (0)
Microsoft Word-25600871-file00.docx (2013) (0)
Abstract 2638: Association between Adriamycin-induced autophagy and senescence in breast cancer cells (2011) (0)
Involvement of p53 in senescence arrest and caspase 3 activity in the cell death response to methotrexate in the breast tumor cell (2004) (0)
The Endocannabinoid System as a Target for Treatment of Breast Cancer (2009) (0)
Caveolin and stat-5 signaling: Potential overlap in lactation and breast tumor promotion (2006) (0)
EMPLOYMENT REGISTER OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (2006) (0)
SILDENAFIL PREVENTS RADIATION-INDUCED CARDIOMYOPATHY IN THE MOUSE (2011) (0)
Abstract 1323: A p53-dependent switch between cytoprotective and nonprotective autophagy influences tumor cell sensitivity to cisplatin (2018) (0)
Award Number: W81XWH-06-1-0360 TITLE: Sildenafil and phosphodiesterase-5 inhibitors to reduce cardiotoxicity and enhance the response of breast tumors to doxorubicin (2007) (0)
Abstract 4278: A comparison of drug sensitivity in isogenic tumor cell lines confirms that cytoprotective autophagy confers intrinsic resistance to cisplatin (2019) (0)
Abstract 5470: Reversibility of therapy-induced senescence in non-small cell lung cancer as a model of cancer recurrence (2017) (0)
Abstract 899: Selective clearance of cells undergoing therapy-induced senescence in a model of triple negative breast cancer (2019) (0)
Abstract 5831: Clearance of therapy-induced senescent cancer cells by the senolytic ABT-263 in a model of non-small cell lung cancer (2020) (0)
Abstract 3221: Analysis of the relationship between autophagy and senescence in response to Adriamycin in breast tumor cells (2010) (0)
Overview. A new discovery phase for antitumor drugs? (2000) (0)
Preface. (2021) (0)
The spectrum of single cell drug response through the lens of long-term high-speed live cell interferometry (2021) (0)
Abstract 3314: Synergistic effects of chemotherapy-induced autophagy and epigenetic remodeling (2017) (0)
Special issue: Autophagic Molecules, Mediators and Modulators in Cancer. (2020) (0)

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