David. A. Gewirtz
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Philosophy Biology
David. A. Gewirtz's Degrees
- PhD Molecular Biology University of California, Berkeley
- Doctorate Medicine Stanford University
Why Is David. A. Gewirtz Influential?
(Suggest an Edit or Addition)David. A. Gewirtz's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
- A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. (1999) (2059)
- Molecular definitions of autophagy and related processes (2017) (1036)
- Autophagy in malignant transformation and cancer progression (2015) (941)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells. (1994) (447)
- Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. (1994) (438)
- The four faces of autophagy: implications for cancer therapy. (2014) (348)
- Autophagy in major human diseases (2021) (282)
- Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation. (2008) (276)
- Adriamycin-induced Senescence in Breast Tumor Cells Involves Functional p53 and Telomere Dysfunction* (2002) (263)
- A comprehensive glossary of autophagy-related molecules and processes (2nd edition) (2011) (259)
- A comprehensive glossary of autophagy-related molecules and processes (2010) (253)
- Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells. (1994) (175)
- Rapid catabolism of 5-fluorouracil in freshly isolated rat hepatocytes as analyzed by high performance liquid chromatography. (1982) (142)
- p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells (2005) (134)
- Therapy-Induced Senescence: An “Old” Friend Becomes the Enemy (2020) (134)
- Dual functions of autophagy in the response of breast tumor cells to radiation (2012) (132)
- Evasion of a Single-Step, Chemotherapy-Induced Senescence in Breast Cancer Cells: Implications for Treatment Response (2005) (131)
- Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy. (2019) (129)
- Autophagy, senescence and tumor dormancy in cancer therapy (2009) (126)
- Autophagy and senescence (2013) (121)
- Cytotoxic Autophagy in Cancer Therapy (2014) (115)
- The Autophagy-Senescence Connection in Chemotherapy: Must Tumor Cells (Self) Eat Before They Sleep? (2012) (115)
- Autophagy and Senescence in Cancer Therapy (2013) (106)
- A Switch Between Cytoprotective and Cytotoxic Autophagy in the Radiosensitization of Breast Tumor Cells by Chloroquine and Vitamin D (2011) (103)
- Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA. (1992) (100)
- Autophagy Inhibition for Chemosensitization and Radiosensitization in Cancer: Do the Preclinical Data Support This Therapeutic Strategy? (2013) (98)
- The combination of a potent vitamin D3 analog, EB 1089, with ionizing radiation reduces tumor growth and induces apoptosis of MCF-7 breast tumor xenografts in nude mice. (2003) (95)
- Promotion of autophagy as a mechanism for radiation sensitization of breast tumor cells. (2009) (94)
- Tumor cell escape from therapy‐induced senescence (2019) (93)
- Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells. (1994) (90)
- Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin. (1994) (89)
- Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy (2021) (86)
- Outcome of early clinical trials of the combination of hydroxychloroquine with chemotherapy in cancer (2014) (84)
- Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery (2006) (82)
- Apoptosis, autophagy, accelerated senescence and reactive oxygen in the response of human breast tumor cells to adriamycin. (2009) (81)
- Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse (2017) (80)
- A novel cytostatic form of autophagy in sensitization of non-small cell lung cancer cells to radiation by vitamin D and the vitamin D analog, EB 1089 (2014) (77)
- Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin. (1996) (76)
- Is Senescence Reversible? (2016) (76)
- HIV-1 and Morphine Regulation of Autophagy in Microglia: Limited Interactions in the Context of HIV-1 Infection and Opioid Abuse (2014) (75)
- The vitamin D3 analog EB 1089 enhances the antiproliferative and apoptotic effects of adriamycin in MCF-7 breast tumor cells (2000) (73)
- Growth arrest and cell death in the breast tumor cell in response to ionizing radiation and chemotherapeutic agents which induce DNA damage (2000) (73)
- Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison. (2007) (73)
- The vitamin D3 analog EB 1089 enhances the response of human breast tumor cells to radiation. (1999) (69)
- The vitamin D3 analog, ILX-23-7553, enhances the response to Adriamycin and irradiation in MCF-7 breast tumor cells (2001) (69)
- Clearance of therapy‐induced senescent tumor cells by the senolytic ABT‐263 via interference with BCL‐XL–BAX interaction (2020) (63)
- An accelerated senescence response to radiation in wild-type p53 glioblastoma multiforme cells. (2006) (61)
- Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells (2016) (61)
- Influence of the phosphodiesterase-5 inhibitor, sildenafil, on sensitivity to chemotherapy in breast tumor cells (2010) (59)
- Erythropoietin Fails to Interfere with the Antiproliferative and Cytotoxic Effects of Antitumor Drugs (2006) (54)
- Formation of methotrexate polyglutamates in rat hepatocytes. (1979) (54)
- Cytoprotective and nonprotective autophagy in cancer therapy (2013) (54)
- Cytotoxicity, DNA strand breakage and DNA-protein crosslinking by a novel transplatinum compound in human A2780 ovarian and MCF-7 breast carcinoma cells. (2004) (54)
- Does bulk damage to DNA explain the cytostatic and cytotoxic effects of topoisomerase II inhibitors? (1991) (53)
- Transport, binding, and polyglutamation of methotrexate in freshly isolated rat hepatocytes. (1980) (52)
- Non-Cell Autonomous Effects of the Senescence-Associated Secretory Phenotype in Cancer Therapy (2018) (52)
- The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy. (2016) (50)
- Influence of p53 and caspase 3 activity on cell death and senescence in response to methotrexate in the breast tumor cell. (2004) (49)
- Yet Another Function of p53—The Switch That Determines Whether Radiation-Induced Autophagy Will Be Cytoprotective or Nonprotective: Implications for Autophagy Inhibition as a Therapeutic Strategy (2015) (46)
- Senolytics for Cancer Therapy: Is All that Glitters Really Gold? (2021) (45)
- Comparative Cardiac Toxicity of Anthracyclines In Vitro and In Vivo in the Mouse (2013) (45)
- Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy (2018) (45)
- Anibamine, a natural product CCR5 antagonist, as a novel lead for the development of anti-prostate cancer agents. (2010) (44)
- An autophagic switch in the response of tumor cells to radiation and chemotherapy. (2014) (44)
- Toxicity issues in cancer drug development. (2010) (44)
- Young plasma reverses age‐dependent alterations in hepatic function through the restoration of autophagy (2017) (44)
- Photocaged permeability: a new strategy for controlled drug release. (2012) (43)
- Docking and hydropathic scoring of polysubstituted pyrrole compounds with antitubulin activity. (2008) (43)
- A chemotherapy-associated senescence bystander effect in breast cancer cells (2008) (42)
- Influence of ionizing radiation on proliferation, c-myc expression and the induction of apoptotic cell death in two breast tumour cell lines differing in p53 status. (1997) (42)
- Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy (2018) (37)
- Effect of the vitamin D3 analog ILX 23-7553 on apoptosis and sensitivity to fractionated radiation in breast tumor cells and normal human fibroblasts (2003) (36)
- The Autophagic Response to Radiation: Relevance for Radiation Sensitization in Cancer Therapy (2014) (36)
- Some considerations in the experimental approach to distinguishing between membrane transport and intracellular disposition of antineoplastic agents, with specific reference to fluorodeoxyuridine, actinomycin D, and methotrexate. (1981) (34)
- Antagonism between tamoxifen and doxorubicin in the MCF-7 human breast tumor cell line. (1994) (33)
- Characterization of a K562 multidrug-resistant cell line. (1989) (33)
- The Roles of Autophagy and Senescence in the Tumor Cell Response to Radiation (2020) (33)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein (2005) (32)
- Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089 (2004) (32)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- A mouse model of radiation-induced cardiomyopathy. (2012) (29)
- Metabolism of adriamycin in hepatocytes isolated from the rat and the rabbit. (1987) (29)
- Triangular Relationship between p53, Autophagy, and Chemotherapy Resistance (2020) (29)
- Evidence for inhibition of growth related to compromised DNA synthesis in the interaction of daunorubicin with H-35 rat hepatoma. (1988) (29)
- Role of Interleukin-1 in Radiation-Induced Cardiomyopathy (2015) (28)
- Influence of amsacrine (m-AMSA) on bulk and gene-specific DNA damage and c-myc expression in MCF-7 breast tumor cells. (1994) (28)
- The lysosome as an imperative regulator of autophagy and cell death (2021) (27)
- Potent bile salt and organic anion inhibition of methotrexate uptake and accumulation in the freshly isolated rat hepatocyte. (1980) (27)
- Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14 (2013) (27)
- When cytoprotective autophagy isn’t… and even when it is (2014) (27)
- Colchicine site inhibitors of microtubule integrity as vascular disrupting agents (2008) (27)
- Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN (2018) (26)
- Apoptosis, senescence, and cancer (2007) (26)
- Importance of Autophagy in Mediating Human Immunodeficiency Virus (HIV) and Morphine-Induced Metabolic Dysfunction and Inflammation in Human Astrocytes (2017) (26)
- Ionizing radiation-induced DNA strand breakage and rejoining in specific genomic regions as determined by an alkaline unwinding/Southern blotting method. (1995) (26)
- Combined Antiproliferative Effects of the Aminoalkylindole WIN55,212-2 and Radiation in Breast Cancer Cells (2014) (26)
- Induction of DNA damage, inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog, idarubicin (4-demethoxy-daunorubicin) in the MCF-7 breast tumor cell line (1998) (26)
- Roles of autophagy in breast cancer treatment: target, bystander or benefactor. (2019) (25)
- Autophagy as a Mechanism of Radiation Sensitization in Breast Tumor Cells (2007) (25)
- Promotion of DNA strand breaks, interstrand cross-links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes. (2007) (25)
- Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer. (2016) (24)
- Tumor Cell Recovery from Senescence Induced by Radiation with PARP Inhibition (2016) (23)
- Modulation of 5-fluorouracil catabolism in isolated rat hepatocytes with enhancement of 5-fluorouracil glucuronide formation. (1985) (23)
- Dissociation between bulk damage to DNA and the antiproliferative activity of teniposide (VM-26) in the MCF-7 breast tumor cell line: evidence for induction of gene-specific damage and alterations in gene expression. (1993) (22)
- A non-calcemic sulfone version of the vitamin D(3) analogue seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin. (2001) (22)
- The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal (2019) (22)
- Induction of Taurocholate Release from Isolated Rat Hepatocytes in Suspension by α‐Adrenergie Agents and Vasopressin: Implications for Control of Bile Salt Secretion (1984) (21)
- Differential Radiation Sensitivity in p53 Wild-Type and p53-Deficient Tumor Cells Associated with Senescence but not Apoptosis or (Nonprotective) Autophagy (2018) (21)
- Effect of pharmacologically relevant concentrations of mitoxantrone on the in vitro growth of leukemic blast progenitors. (1991) (21)
- Targeting tumor cell senescence and polyploidy as potential therapeutic strategies. (2020) (21)
- Effects of Tamoxifen on the Radiosensitivity of Hormonally Responsive and Unresponsive Breast Carcinoma Cells (1993) (19)
- Stimulation of taurocholate and glycocholate efflux from the rat hepatocyte by arginine vasopressin. (1988) (19)
- Interference with endothelial cell function by JG-03-14, an agent that binds to the colchicine site on microtubules. (2009) (19)
- Autophagy and radiosensitization in cancer (2014) (19)
- Sustained enhancement of liposome-mediated gene delivery and gene expression in human breast tumour cells by ionizing radiation. (1999) (18)
- Suppression of c-myc expression and c-Myc function in response to sustained DNA damage in MCF-7 breast tumor cells. (2001) (17)
- Modulation of transplanaramine platinum complex reactivity by systematic modification of carrier and leaving groups (2009) (17)
- Vitamin D3 and vitamin D3 analogues as an adjunct to cancer chemo-therapy and radiotherapy. (2002) (17)
- Interaction of probenecid with methotrexate transport and release in the isolated rat hepatocyte in suspension. (1984) (17)
- The natural product CCR5 antagonist anibamine and its analogs as anti-prostate cancer agents. (2011) (16)
- QW-1624F2-2, a synthetic analogue of 1,25-dihydroxyvitamin D3, enhances the response to other deltanoids and suppresses the invasiveness of human metastatic breast tumor cells (2006) (15)
- Targeting Peroxisome Proliferator-Activated Receptor-α (PPAR- α) to reduce paclitaxel-induced peripheral neuropathy (2021) (15)
- A combined alkaline unwinding/Southern blotting assay for measuring low levels of cellular DNA breakage within specific genomic regions. (1992) (15)
- The Influence of Nicotine on Lung Tumor Growth, Cancer Chemotherapy, and Chemotherapy-Induced Peripheral Neuropathy (2018) (15)
- Young plasma attenuates age‐dependent liver ischemia reperfusion injury (2018) (14)
- Accelerated partial-breast irradiation: trial by media or by science? (2012) (14)
- Influence of nonprotective autophagy and the autophagic switch on sensitivity to cisplatin in non-small cell lung cancer cells. (2020) (14)
- Biochemical lesions in DNA associated with the antiproliferative effects of mitoxantrone in the hepatoma cell. (1990) (14)
- Metabolism of the anthracycline antibiotic daunorubicin to daunorubicinol and deoxydaunorubicinol aglycone in hepatocytes isolated from the rat and the rabbit. (1986) (14)
- Induction of DNA damage, inhibition of DNA synthesis, and suppression of c-myc expression by the topoisomerase I inhibitor, camptothecin, in MCF-7 human breast tumor cells. (1998) (13)
- Efflux in isolated hepatocytes as a possible correlate of secretion in vivo: induced exit of the folic acid analog methotrexate, by dibutyryl cyclic AMP or isobutyl methyl xanthine. (1981) (13)
- Estradiol enhances gene delivery to human breast tumor cells (1998) (13)
- Autophagy, senescence, and apoptosis. (2013) (13)
- Evidence from rat hepatocytes of an unrecognized pathway of 5-fluorouracil metabolism with the formation of a glucuronide derivative. (1985) (13)
- Proteomics Insights into Autophagy (2017) (12)
- Characteristics of the formation and membrane transport of 7-hydroxymethotrexate in freshly isolated rabbit hepatocytes. (1985) (12)
- Influence of topoisomerase II inhibitors and ionizing radiation on growth arrest and cell death pathways in the breast tumor cell (2007) (12)
- Enhancement of radiation sensitivity, delay of proliferative recovery after radiation and abrogation of MAPK (p44/42) signaling by imatinib in glioblastoma cells. (2006) (11)
- Radiosensitization of HL-60 human leukaemia cells by bryostatin-1 in the absence of increased DNA fragmentation or apoptotic cell death. (1996) (11)
- The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer (2020) (11)
- DNA damage, gene expression, growth arrest and cell death. (1993) (11)
- Ionizing radiation and teniposide increase p21(waf1/cip1) and promote Rb dephosphorylation but fail to suppress E2F activity in MCF-7 breast tumor cells. (1997) (10)
- Is Autophagy Always a Barrier to Cisplatin Therapy? (2022) (10)
- Androgen-deprivation induced senescence in prostate cancer cells is permissive for the development of castration-resistance but susceptible to senolytic therapy. (2021) (10)
- Catecholamine-induced release of the folic acid analogue, methotrexate, from rat hepatocytes in suspension. An alpha-adrenergic phenomenon. (1982) (10)
- Estradiol enhances liposome-mediated uptake, preferential nuclear accumulation and functional expression of exogenous genes in MDA-MB231 breast tumor cells. (1999) (10)
- Considering therapy-induced senescence as a mechanism of tumour dormancy contributing to disease recurrence (2022) (10)
- Abstract 4652: The autophagy-senescence connection in chemotherapy of breast tumor cells; senescence accelerated by autophagy but not dependent on autophagy (2012) (9)
- Enhanced sensitivity of the rat hepatoma cell to the daunorubicin analogue 4-demethoxydaunorubicin associated with induction of DNA damage. (1989) (9)
- Enhancement of liposomal gene delivery in human breast cancer cells by dimethyl sulfoxide. (1998) (9)
- Senescence and castration resistance in prostate cancer: A review of experimental evidence and clinical implications. (2020) (8)
- The potentially conflicting cell autonomous and cell non‐autonomous functions of autophagy in mediating tumor response to cancer therapy (2018) (8)
- Apoptosis as the predominant tumor cell response to chemotherapy and irradiation: a case of TUNEL vision? (2005) (8)
- Transcriptional down-regulation of c-myc expression in the MCF-7 breast tumor cell line by the topoisomerase II inhibitor, VM-26. (1995) (8)
- Protein binding as a component of drug interaction in cellular pharmacokinetic studies. Effects of probenecid on transport and accumulation of methotrexate in Ehrlich ascites tumor cells in vitro. (1985) (8)
- Receptor-mediated stimulation of taurocholate efflux from the rat hepatocyte and the ex vivo perfused rat liver. (1990) (8)
- Rb dephosphorylation and suppression of E2F activity in human breast tumor cells exposed to a pharmacological concentration of estradiol. (2001) (7)
- A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice (2020) (7)
- Stilbene 5c, a microtubule poison with vascular disrupting properties that induces multiple modes of growth arrest and cell death. (2013) (7)
- Fluvastatin Induces Apoptosis in Primary and Transformed Mast Cells (2020) (6)
- Autophagy Inhibition and Chemosensitization in Cancer Therapy (2019) (6)
- An overview of chemotoxicity and radiation toxicity in cancer therapy. (2022) (6)
- Autophagy and senescence in cancer therapy. (2021) (5)
- Reversibility of chemotherapy-induced senescence is independent of autophagy and a potential model for tumor dormancy and cancer recurrence (2017) (5)
- Characteristics of the accumulation of methotrexate polyglutamate derivatives in Ehrlich ascites tumor cells and isolated rat hepatocytes. (1983) (5)
- N‐acylethanolamine‐hydrolysing acid amidase: A new potential target to treat paclitaxel‐induced neuropathy (2021) (4)
- The Cytoprotective, Cytotoxic and Nonprotective Functional Forms of Autophagy Induced by Microtubule Poisons in Tumor Cells—Implications for Autophagy Modulation as a Therapeutic Strategy (2022) (4)
- Senolytic-Mediated Elimination of Head and Neck Tumor Cells Induced Into Senescence by Cisplatin (2021) (4)
- Therapeutic Potential for Targeting Autophagy in ER+ Breast Cancer (2022) (3)
- Disentangling the Mechanisms of Radiation-Induced Heart Disease in the Treatment of Breast Cancer (2015) (3)
- Anibamine, a Natural Product CCR5 Antagonist, as a Novel Lead for the Development of Antiprostate Cancer Agents. (2010) (3)
- Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization. (1989) (3)
- Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor (2021) (3)
- Abstract 2663: Dual cytoprotective and cytotoxic functions of autophagy in the response ofbreast tumor cells to radiation and in radiosensitization by vitamin D3 (2011) (2)
- Abstract 17799: Role Of Interleukin-1 In Acute Radiation-induced Cardiomyopathy (2012) (2)
- Application of quantitative phase imaging mass accumulation measurements to research and clinical problems in cancer (2019) (2)
- Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors (2022) (2)
- Autophagy, Stem Cells, and Tumor Dormancy (2014) (2)
- Abstract 14774: Preserved Left Ventricular Contractile Reserve After Thoracic Irradiation in the Interleukin-1 Receptor Knock Out Mouse (2013) (2)
- Loss of sphingosine kinase 2 protects against cisplatin induced-kidney injury. (2022) (2)
- Abstract 3528: Induction of cytoprotective autophagy and senescence in response to chemotherapy and ionizing-radiation as possible mechanisms of tumor dormancy (2016) (1)
- Abstract 902: The antiandrogen bicalutamide induces senescence in LNCaP cells and quiescence in Myc CaP cells (2019) (1)
- Abstract 2385: Involvement of autophagy and senescence in DNA repair in irradiated tumor cells (2014) (1)
- Abstract 998: Induction of non-protective autophagy by radiation in tumor cells: Implications for autophagy inhibition as a therapeutic strategy (2015) (1)
- Abstract 2846: Proliferative recovery after chemotherapy-induced senescence in non-small cell lung cancer (NSCLC) cells as a model of tumor dormancy and disease recurrence (2016) (1)
- The nuclear receptor TLX (NR2E1) inhibits growth and progression of triple- negative breast cancer. (2022) (1)
- Topoisomerase I poisons-induced autophagy: Cytoprotective, Cytotoxic or Non-protective. (2022) (1)
- Ionizing Radiation and Teniposide Increase p 21 waf 1 / cip 1 and Promote Rb Dephosphorylation but Fail to Suppress E 2 F Activity in MCF-7 Breast Tumor Cells (1997) (1)
- Sorafenib, rapamycin, and venetoclax attenuate doxorubicin-induced senescence and promote apoptosis in HCT116 cells (2021) (1)
- Serum protein reduction of the enhancement of methotrexate accumulation by vincristine and 4'-demethylepipodophyllotoxin in the Ehrlich ascites tumor cell in vitro. (1985) (1)
- Variable effects of tamoxifen on human hematopoietic progenitor cell growth and sensitivity to doxorubicin (2004) (1)
- Evidencefrom Rat Hepatocytesof an UnrecognizedPathwayof 5-Fluorouracil Metabolismwith the Formationof a GlucuronideDerivative1 (1985) (1)
- The BET inhibitor/degrader ARV-825 prolongs the growth arrest response to Fulvestrant + Palbociclib and suppresses proliferative recovery in ER-positive breast cancer (2023) (1)
- Leveraging Epigenetics to Enhance the Cellular Response to Chemotherapies and Improve Tumor Immunogenicity (2018) (1)
- Abstract 14880: Interleukin-18 in Radiation-induced Cardiomyopathy (2014) (1)
- Abstract 1453: The cannabinoid Win55, 212-2 enhances the response of breast cancer cells to radiation (2012) (1)
- Induction of methotrexate release from rat hepatocytes in suspension by alpha-adrenergic agents: involvement of calcium and metabolic energy. (1985) (1)
- The role of senescence in the action of antitumor drugs. (2008) (1)
- Abstract 460: Reversibility of chemotherapy-induced senescence in breast tumor cells in culture and in vivo (2018) (0)
- Abstract 5665: New alternatives to photodynamic therapy based on light-enabled drug delivery. (2013) (0)
- Abstract 5550: Autophagic potentiation of radiosensitization by vitamin D3 and the analog, EB1089 (2010) (0)
- Hepatoma Synthesis in the Interaction of Daunorubicin with H-35 Rat Evidence for Inhibition of Growth Related to Compromised DNA Updated (2006) (0)
- The Natural Product CCR5 Antagonist Anibamine and Its Analogues as Antiprostate Cancer Agents. (2012) (0)
- Association with Enhanced Fragmentation of Mature DNA by the Protein Kinase C Activator Bryostatin 1 in HL-60 Cells :d-Arabinofuranosylcytosine β Potentiation of the Activity of 1-Updated (2006) (0)
- Abstract 5459: Autophagy and senescence as possible mechanisms leading to proliferative recovery and escape from treatment-induced tumor dormancy (2017) (0)
- Molecular basis for the accelerated senescence response to Adriamycin in MCF-7 breast and HCT-116 tumor cells (2006) (0)
- Comprar Apoptosis, Senescence and Cancer | Gewirtz, David A. | 9781588295279 | Springer (2008) (0)
- Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy? (2023) (0)
- Vitamin D and the Risk of Cancer (2005) (0)
- Investigations into the cellular mechanism of action of transplanaramines of the type trans-[Pt (O2CR)2 (L) (L’)] (2007) (0)
- Senolytic Therapy: A Potential Approach for the Elimination of Oncogene-Induced Senescent HPV-Positive Cells (2022) (0)
- Abstract 3299: Radiation induced p53-dependent cytoprotective autophagy fails to reduce radiation sensitivity in H460 non-small cell lung cancer cells (2017) (0)
- Review article: AUTOPHAGY AND RADIOSENSITIZATION IN CANCER (2014) (0)
- Abstract 2675: Radiosensitization of breast cancer cells by Vitamin D or chloroquine through modulation of the dual cytoprotective and cytotoxic functions of autophagy (2011) (0)
- Knockout of fatty acid amide hydrolase (FAAH) gene attenuates cisplatin‐induced nephrotoxicity in mice (2022) (0)
- Characterization of a K 562 Multidrug-resistant Cell Line 1 (2006) (0)
- Abstract 1330: Role of epigenetic remodeling in sensitizing triple-negative breast cancer cells to treatment through enhanced chemotherapy-induced autophagy (2018) (0)
- Treatment Induced Autophagy Associated with Tumor Dormancy and Relapse (2016) (0)
- Abstract #869: Potentiation of the response to ionizing radiation in breast tumor cells by the vitamin D3 analog, EB 1089 (2009) (0)
- Abstract 1326: Nonprotective autophagy fails to confer resistance to radiation (2018) (0)
- Cleavage/Repair and Signal Transduction Pathways in Irradiated Breast Tumor Cells (2000) (0)
- Award Number: W81XWH-06-1-0360 TITLE: Sildenafil and Phosphofiesterase-5 Inhibitors to Reduce Cardiotoxicity and Enhance the Response of Breast Tumors to Doxrubicin (2008) (0)
- Abstract 993: The relationship between autophagy, senescence, and DNA repair (2015) (0)
- Abstract 1329: Sensitization of non-small cell lung cancer cells (NSCLC) to radiation by Vitamin D (EB 1089) (2013) (0)
- Medical Science 7 nAChR NEGATIVE ALLOSTERISM : A PROMISING APPROACH FOR COGNITIVE DISORDERS (0)
- TITLE : Stimulation of Breast Tumor Cell Proliferative Recovery by the Peptide Hormone Erythropoietin PRINCIPAL INVESTIGATOR : (2006) (0)
- Abstract 2024: Studying the effects of interfering with doxorubicin-induced senescence in human colon cancer HCT116 cells (2021) (0)
- Abstract 459: Therapy-induced senescence is reversible in vitro and in vivo (2018) (0)
- Abstract LB133: EGFR upregulation in breast cancer cells: A key mechanism of escape from antiestrogen induced death, autophagy, and senescence (2022) (0)
- Analysis of 3H fluorouracil (FUra) catabolism by HPLC in freshly isolated rat hepatocytes (1982) (0)
- Abstract 4114: Dual cytoprotective and cytotoxic functions of autophagy in the response of breast tumor cells to radiation and in radiosensitization by vitamin D3 (2012) (0)
- Abstract 15830: ‘Out of Target’ Radiation Therapy Leads to Impaired Cardiac Contractile Reserve in the Mouse (2015) (0)
- Sildenafil and Phosphodiesterase-5 Inhibitors to Reduce Cardiotoxicity and Enhance the Response of Breast Tumor Cells to Doxorubicin (2010) (0)
- Abstract 1454: The role of AMPK in the radiosensitization of breast tumor cells by Vitamin D (2012) (0)
- Abstract 3539: Vitamin D/EB 1089 mediated radio-sensitization of lung cancer cells and head and neck cancer cells (2016) (0)
- Cellular senescence as a target to inhibit epithelial‐mesenchymal transition in HK‐2 cells (2021) (0)
- Potentiation of the Activity of l-ß-o-Arabinofuranosylcytosine by the Protein Kinase C Activator Bryostatin 1 in HL-60 Cells: Association with Enhanced Fragmentation of Mature DNA1 (2006) (0)
- Ionizing radiation-induced senescence of breast tumor cells is dependent on p53 and associated with telomere dysfunction. (2004) (0)
- Nephrotoxicity in cancer treatment: An update. (2022) (0)
- “Emerging Concepts”: New Article Category in Molecular Pharmacology (2020) (0)
- Abstract 986: Targeting nicotinic acetylcholine receptors for the prevention and reversal of chemotherapy-induced peripheral neuropathy (2017) (0)
- Abstract 602: The α7 nicotinic acetylcholine receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy without enhancing the proliferation of lung cancer cells or interfering with paclitaxel-induced antitumor activity (2018) (0)
- Abstract 1465: Radiosensitization of NSCLC through modulation of autophagy and senescence (2012) (0)
- Abstract 4272: Suppression of epigenetic regulator NURF leads to autophagy mediated chemo-and immune sensitization of triple negative breast cancer (2019) (0)
- Editorial: Risks and Benefits of Adjuvants to Cancer Therapies (2022) (0)
- Alpha adrenergic agents and vasopressin induce release (secretion) of the bile salt taurocholate from isolated rat hepatocytes in suspension (1982) (0)
- Abstract 227: Mass spectrometry-based proteomics analysis of the non-small cell lung cancer secretome (2017) (0)
- Abstract 3574: Nicotine prevents chemotherapy-induced peripheral neuropathy in vivo, and fails to stimulate the growth of lung cancer cells or interfere with the effectiveness of chemotherapy in vitro (2016) (0)
- Elucidation of the mechanisms underlying the potentiation of cell killing by ionizing radiation in MCF-7 breast tumor cells by the vitamin D3 analog EB 1089 (2006) (0)
- Preface. (2022) (0)
- Genetic Knockout of Fatty Acid Amide Hydrolase Ameliorates Cisplatin-Induced Nephropathy in Mice (2023) (0)
- Studies on the heat-precipitated phosphoenzyme complex of eel electric organ (Na + K).ATPase. (1979) (0)
- Abstract 3957: Cell death and growth arrest pathways mediating the actions of stilbene 5C in HCT-116 colon cancer cells (2012) (0)
- Fornari Induction of DNA damage , inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog (0)
- Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach (2019) (0)
- Involvement of the Endocannabinoid System in the Development and Treatment of Breast Cancer (2014) (0)
- Abstract 1400: Mitigation of radiation-induced injury with the nitric oxide synthase co-factor, tetrahydrobiopterin (2010) (0)
- Senescence in prostate cancer: is there sufficient evidence to move forward? (2021) (0)
- Abstract 2848: Autophagy, senescence and proliferative recovery subsequent to DNA damage in radiation sensitization by PARP inhibition (2016) (0)
- Abstract 1013: Understanding the molecular pathways underlying radio-sensitization of non-small cell lung cancer (NSCLC) by vitamin D (EB1089) (2015) (0)
- Functional Characterization of the Orphan Nuclear Receptor TLX in Triple Negative Breast Cancer (2021) (0)
- Stimulation of Breast Tumor Cell Proliferative Recovery by the Peptide Hormone Erythropoietin (2006) (0)
- List of Referees, 2009 (2010) (0)
- Microsoft Word-25600871-file00.docx (2013) (0)
- Abstract 2638: Association between Adriamycin-induced autophagy and senescence in breast cancer cells (2011) (0)
- Involvement of p53 in senescence arrest and caspase 3 activity in the cell death response to methotrexate in the breast tumor cell (2004) (0)
- The Endocannabinoid System as a Target for Treatment of Breast Cancer (2009) (0)
- Caveolin and stat-5 signaling: Potential overlap in lactation and breast tumor promotion (2006) (0)
- EMPLOYMENT REGISTER OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (2006) (0)
- SILDENAFIL PREVENTS RADIATION-INDUCED CARDIOMYOPATHY IN THE MOUSE (2011) (0)
- Abstract 1323: A p53-dependent switch between cytoprotective and nonprotective autophagy influences tumor cell sensitivity to cisplatin (2018) (0)
- Award Number: W81XWH-06-1-0360 TITLE: Sildenafil and phosphodiesterase-5 inhibitors to reduce cardiotoxicity and enhance the response of breast tumors to doxorubicin (2007) (0)
- Abstract 4278: A comparison of drug sensitivity in isogenic tumor cell lines confirms that cytoprotective autophagy confers intrinsic resistance to cisplatin (2019) (0)
- Abstract 5470: Reversibility of therapy-induced senescence in non-small cell lung cancer as a model of cancer recurrence (2017) (0)
- Abstract 899: Selective clearance of cells undergoing therapy-induced senescence in a model of triple negative breast cancer (2019) (0)
- Abstract 5831: Clearance of therapy-induced senescent cancer cells by the senolytic ABT-263 in a model of non-small cell lung cancer (2020) (0)
- Abstract 3221: Analysis of the relationship between autophagy and senescence in response to Adriamycin in breast tumor cells (2010) (0)
- Overview. A new discovery phase for antitumor drugs? (2000) (0)
- Preface. (2021) (0)
- The spectrum of single cell drug response through the lens of long-term high-speed live cell interferometry (2021) (0)
- Abstract 3314: Synergistic effects of chemotherapy-induced autophagy and epigenetic remodeling (2017) (0)
- Special issue: Autophagic Molecules, Mediators and Modulators in Cancer. (2020) (0)
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