David Baker
#14,212
Most Influential Person Now
American biochemist, computational biologist
David Baker 's AcademicInfluence.com Rankings
David Baker biology Degrees
Biology
#773
World Rank
#1337
Historical Rank
#416
USA Rank
Computational Biology
#10
World Rank
#10
Historical Rank
#6
USA Rank
Biochemistry
#98
World Rank
#127
Historical Rank
#57
USA Rank
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Biology
David Baker 's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is David Baker Influential?
(Suggest an Edit or Addition)According to Wikipedia, David Baker is an American biochemist and computational biologist who has pioneered methods to predict and design the three-dimensional structures of proteins. He is the Henrietta and Aubrey Davis Endowed Professor in Biochemistry and an adjunct professor of genome sciences, bioengineering, chemical engineering, computer science, and physics at the University of Washington. He serves as the director of the Rosetta Commons, a consortium of labs and researchers that develop biomolecular structure prediction and design software. The problem of protein structure prediction to which Baker has contributed significantly has now been largely solved by DeepMind using artificial intelligence. Baker is a Howard Hughes Medical Institute investigator and a member of the United States National Academy of Sciences. He is also the director of the University of Washington's Institute for Protein Design.
David Baker 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Protein structure prediction and analysis using the Robetta server (2004) (1622)
- Protein Structure Prediction Using Rosetta (2004) (1591)
- Protein Structure Prediction and Structural Genomics (2001) (1586)
- Design of a Novel Globular Protein Fold with Atomic-Level Accuracy (2003) (1522)
- ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules. (2011) (1504)
- Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions. (1997) (1401)
- Contact order, transition state placement and the refolding rates of single domain proteins. (1998) (1384)
- Predicting protein structures with a multiplayer online game (2010) (1302)
- Quantitative reactivity profiling predicts functional cysteines in proteomes (2010) (1196)
- Kemp elimination catalysts by computational enzyme design (2008) (1139)
- Improving physical realism, stereochemistry, and side‐chain accuracy in homology modeling: Four approaches that performed well in CASP8 (2009) (1093)
- Accurate prediction of protein structures and interactions using a 3-track neural network (2021) (1055)
- Protein-protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations. (2003) (1051)
- De Novo Computational Design of Retro-Aldol Enzymes (2008) (1011)
- High-resolution comparative modeling with RosettaCM. (2013) (874)
- The coming of age of de novo protein design (2016) (869)
- Macromolecular modeling with rosetta. (2008) (857)
- Toward High-Resolution de Novo Structure Prediction for Small Proteins (2005) (852)
- Improved protein structure prediction using predicted interresidue orientations (2019) (835)
- Consistent blind protein structure generation from NMR chemical shift data (2008) (806)
- A simple physical model for binding energy hot spots in protein–protein complexes (2002) (789)
- The Rosetta all-atom energy function for macromolecular modeling and design (2017) (788)
- Native protein sequences are close to optimal for their structures. (2000) (785)
- Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction (2010) (759)
- Using chlorophyll fluorescence to assess the fraction of absorbed light allocated to thermal dissipa (2008) (743)
- A surprising simplicity to protein folding (2000) (708)
- Assessing the utility of coevolution-based residue–residue contact predictions in a sequence- and structure-rich era (2013) (578)
- Ab initio protein structure prediction of CASP III targets using ROSETTA (1999) (574)
- Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy (2012) (538)
- Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin (2011) (537)
- Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information (2014) (517)
- Crystal structure of a monomeric retroviral protease solved by protein folding game players (2011) (505)
- High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis (2014) (504)
- Computational Alanine Scanning of Protein-Protein Interfaces (2004) (496)
- Ca2+ indicators based on computationally redesigned calmodulin-peptide pairs. (2006) (492)
- Role of conformational sampling in computing mutation‐induced changes in protein structure and stability (2011) (489)
- An orientation-dependent hydrogen bonding potential improves prediction of specificity and structure for proteins and protein-protein complexes. (2003) (485)
- Principles for designing ideal protein structures (2012) (473)
- Algorithm discovery by protein folding game players (2011) (460)
- Improved recognition of native‐like protein structures using a combination of sequence‐dependent and sequence‐independent features of proteins (1999) (459)
- High Resolution Mapping of Protein Sequence–Function Relationships (2010) (458)
- Structure prediction for CASP8 with all‐atom refinement using Rosetta (2009) (446)
- Accurate design of co-assembling multi-component protein nanomaterials (2014) (442)
- Mechanisms of protein folding. (2001) (433)
- RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite (2011) (427)
- Protein-protein docking with backbone flexibility. (2007) (425)
- Automated de novo prediction of native-like RNA tertiary structures (2007) (415)
- ROSETTALIGAND: Protein–small molecule docking with full side‐chain flexibility (2006) (409)
- RosettaLigand docking with full ligand and receptor flexibility. (2009) (385)
- Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila (1991) (383)
- Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation (2011) (372)
- The 3D profile method for identifying fibril-forming segments of proteins. (2006) (371)
- Accurate design of megadalton-scale two-component icosahedral protein complexes (2016) (370)
- Measurement of Catalyst Layer Electrolyte Resistance in PEFCs Using Electrochemical Impedance Spectroscopy (2005) (369)
- Experiment and theory highlight role of native state topology in SH3 folding (1999) (367)
- Prediction of protein-folding mechanisms from free-energy landscapes derived from native structures. (1999) (359)
- Computational design of ligand-binding proteins with high affinity and selectivity (2013) (358)
- Topology, stability, sequence, and length: defining the determinants of two-state protein folding kinetics. (2000) (356)
- Global analysis of protein folding using massively parallel design, synthesis, and testing (2017) (348)
- Direct in situ measurements of Li transport in Li-ion battery negative electrodes (2009) (347)
- Prediction of local structure in proteins using a library of sequence-structure motifs. (1998) (347)
- HMMSTR: a hidden Markov model for local sequence-structure correlations in proteins. (2000) (344)
- Atomic model of the type III secretion system needle (2012) (341)
- Ab initio protein structure prediction: progress and prospects. (2001) (340)
- Macromolecular modeling and design in Rosetta: recent methods and frameworks (2020) (339)
- Modeling structurally variable regions in homologous proteins with rosetta (2004) (336)
- Critical role of β-hairpin formation in protein G folding (2000) (332)
- Contact order revisited: Influence of protein size on the folding rate (2003) (332)
- Computational redesign of endonuclease DNA binding and cleavage specificity (2006) (330)
- Multipass membrane protein structure prediction using Rosetta (2005) (329)
- Atomic accuracy in predicting and designing non-canonical RNA structure (2010) (325)
- New algorithms and an in silico benchmark for computational enzyme design (2006) (313)
- High-resolution structure prediction and the crystallographic phase problem (2007) (311)
- Reconstitution of SEC gene product-dependent intercompartmental protein transport (1988) (311)
- A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins. (2003) (310)
- Rosetta in CASP4: Progress in ab initio protein structure prediction (2001) (306)
- Atomic accuracy models from 4.5 Å cryo-electron microscopy data with density-guided iterative local refinement (2015) (298)
- Massively parallel de novo protein design for targeted therapeutics (2017) (298)
- Progress in Modeling of Protein Structures and Interactions (2005) (298)
- Elicitation of structure-specific antibodies by epitope scaffolds (2010) (292)
- Computational redesign of protein-protein interaction specificity (2004) (292)
- Important role of hydrogen bonds in the structurally polarized transition state for folding of the src SH3 domain (1998) (291)
- Automated prediction of CASP‐5 structures using the Robetta server (2003) (290)
- Assigning function to yeast proteins by integration of technologies. (2003) (290)
- Functional rapidly folding proteins from simplified amino acid sequences (1997) (287)
- Measurement of Oxygen Transport Resistance in PEM Fuel Cells by Limiting Current Methods (2009) (286)
- Design of a hyperstable 60-subunit protein icosahedron (2016) (280)
- Refinement of protein structures into low-resolution density maps using rosetta. (2009) (277)
- Simultaneous Optimization of Biomolecular Energy Functions on Features from Small Molecules and Macromolecules. (2016) (276)
- Clustering of low-energy conformations near the native structures of small proteins. (1998) (274)
- De novo prediction of three-dimensional structures for major protein families. (2002) (269)
- Solution structure of a minor and transiently formed state of a T4 lysozyme mutant (2011) (267)
- Relaxation of backbone bond geometry improves protein energy landscape modeling (2014) (266)
- RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design (2011) (265)
- Alternate states of proteins revealed by detailed energy landscape mapping. (2011) (265)
- De Novo Enzyme Design Using Rosetta3 (2011) (264)
- A protein-folding reaction under kinetic control (1992) (263)
- Increased Diels-Alderase activity through backbone remodeling guided by Foldit players (2012) (261)
- De novo protein structure generation from incomplete chemical shift assignments (2009) (261)
- De novo design of picomolar SARS-CoV-2 miniprotein inhibitors (2020) (250)
- Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus (2019) (250)
- Computational design of protein-protein interactions. (2004) (245)
- De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity (2016) (234)
- Computational protein design enables a novel one-carbon assimilation pathway (2015) (233)
- Improved side‐chain modeling for protein–protein docking (2005) (229)
- Improved molecular replacement by density- and energy-guided protein structure optimization (2011) (228)
- Engineering an allosteric transcription factor to respond to new ligands (2015) (227)
- Structural basis for gating charge movement in the voltage sensor of a sodium channel (2011) (227)
- Voltage sensor conformations in the open and closed states in ROSETTA structural models of K(+) channels. (2006) (226)
- High thermodynamic stability of parametrically designed helical bundles (2014) (226)
- Structure prediction for CASP7 targets using extensive all‐atom refinement with Rosetta@home (2007) (222)
- Close agreement between the orientation dependence of hydrogen bonds observed in protein structures and quantum mechanical calculations. (2004) (221)
- Kinetics versus thermodynamics in protein folding. (1994) (221)
- A breakdown of symmetry in the folding transition state of protein L. (2000) (220)
- Large-scale determination of previously unsolved protein structures using evolutionary information (2015) (218)
- Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold (2011) (217)
- Computer-based redesign of a protein folding pathway (2001) (216)
- Coupled prediction of protein secondary and tertiary structure (2003) (207)
- A Vast Repertoire of Dscam Binding Specificities Arises from Modular Interactions of Variable Ig Domains (2007) (207)
- Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase (2016) (207)
- Structure of the Type VI Secretion System Contractile Sheath (2015) (205)
- Evaluation of structural and evolutionary contributions to deleterious mutation prediction. (2002) (205)
- Combined covalent-electrostatic model of hydrogen bonding improves structure prediction with Rosetta. (2015) (202)
- Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus (2011) (200)
- Evolution of a designed retro-aldolase leads to complete active site remodeling (2013) (200)
- Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes (2018) (199)
- Exploring the repeat protein universe through computational protein design (2015) (199)
- Toward high-resolution prediction and design of transmembrane helical protein structures (2007) (199)
- De novo design of a fluorescence-activating β-barrel (2018) (198)
- Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples (2012) (196)
- Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59 (2012) (196)
- Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis. (2012) (195)
- Prospects for ab initio protein structural genomics. (2001) (194)
- Rosetta predictions in CASP5: Successes, failures, and prospects for complete automation (2003) (193)
- Scientific benchmarks for guiding macromolecular energy function improvement. (2013) (191)
- A Pareto-Optimal Refinement Method for Protein Design Scaffolds (2013) (191)
- Design of ordered two-dimensional arrays mediated by noncovalent protein-protein interfaces (2015) (191)
- Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling (2017) (190)
- De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy (2015) (189)
- A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system (2009) (188)
- Proton Conduction and Oxygen Reduction Kinetics in PEM Fuel Cell Cathodes: Effects of Ionomer-to-Carbon Ratio and Relative Humidity (2009) (185)
- Protein–DNA binding specificity predictions with structural models (2005) (185)
- De novo protein structure determination using sparse NMR data (2000) (184)
- Realistic protein–protein association rates from a simple diffusional model neglecting long‐range interactions, free energy barriers, and landscape ruggedness (2004) (182)
- Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity (2019) (182)
- De novo determination of protein backbone structure from residual dipolar couplings using Rosetta. (2002) (182)
- In situ investigation of water transport in an operating PEM fuel cell using neutron radiography: Part 2 – Transient water accumulation in an interdigitated cathode flow field (2006) (181)
- Generalized Fragment Picking in Rosetta: Design, Protocols and Applications (2011) (179)
- Modeling Symmetric Macromolecular Structures in Rosetta3 (2011) (177)
- Computed structures of core eukaryotic protein complexes (2021) (176)
- An improved protein decoy set for testing energy functions for protein structure prediction (2003) (174)
- Folding dynamics of the src SH3 domain. (1997) (174)
- The challenge of designing scientific discovery games (2010) (173)
- A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3). (2009) (173)
- Prediction of the structure of symmetrical protein assemblies (2007) (172)
- Physically realistic homology models built with ROSETTA can be more accurate than their templates. (2006) (172)
- De novo protein design by deep network hallucination (2020) (170)
- Chain collapse can occur concomitantly with the rate-limiting step in protein folding (1999) (169)
- An exciting but challenging road ahead for computational enzyme design (2010) (167)
- Improved low-resolution crystallographic refinement with Phenix and Rosetta (2013) (167)
- De novo protein structure determination from near-atomic resolution cryo-EM maps (2015) (166)
- The role of pro regions in protein folding. (1993) (164)
- A de novo protein binding pair by computational design and directed evolution. (2011) (164)
- Progress and challenges in high‐resolution refinement of protein structure models (2005) (163)
- GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction. (1990) (160)
- The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. (2011) (158)
- Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis (1993) (158)
- Prediction of CASP6 structures using automated robetta protocols (2005) (156)
- megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering (2013) (155)
- De Novo Design of Bioactive Protein Switches (2019) (155)
- Optimization of the in-silico-designed kemp eliminase KE70 by computational design and directed evolution. (2011) (155)
- Matching theory and experiment in protein folding. (1999) (155)
- Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series. (2010) (154)
- Free modeling with Rosetta in CASP6 (2005) (153)
- Prediction of membrane protein structures with complex topologies using limited constraints (2009) (153)
- Emergence of symmetry in homooligomeric biological assemblies (2008) (152)
- Computational design of a new hydrogen bond network and at least a 300-fold specificity switch at a protein-protein interface. (2006) (151)
- De novo design of picomolar SARS-CoV-2 miniprotein inhibitors (2020) (149)
- Limited internal friction in the rate-limiting step of a two-state protein folding reaction. (1998) (147)
- A “solvated rotamer” approach to modeling water‐mediated hydrogen bonds at protein–protein interfaces (2005) (146)
- Protein interaction networks revealed by proteome coevolution (2019) (146)
- Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability. (1997) (145)
- Evolution of a designed protein assembly encapsulating its own RNA genome (2017) (144)
- Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast (1988) (143)
- Molecular dynamics in the endgame of protein structure prediction. (2001) (143)
- The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3. (2009) (140)
- The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection (2007) (140)
- Simultaneous prediction of protein folding and docking at high resolution (2009) (140)
- Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring. (2014) (139)
- Community-wide assessment of protein-interface modeling suggests improvements to design methodology. (2011) (139)
- Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy (2007) (137)
- The trRosetta server for fast and accurate protein structure prediction (2021) (135)
- Origins of coevolution between residues distant in protein 3D structures (2017) (134)
- Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3 (2017) (133)
- Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130. (2003) (133)
- Long-range order in the src SH3 folding transition state. (2000) (132)
- Kinetics of folding of the IgG binding domain of peptostreptococcal protein L. (1997) (131)
- phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta (2012) (131)
- Global properties of the mapping between local amino acid sequence and local structure in proteins. (1996) (130)
- Improved protein structure refinement guided by deep learning based accuracy estimation (2020) (130)
- RosettaHoles: Rapid assessment of protein core packing for structure prediction, refinement, design, and validation (2008) (126)
- A general strategy to construct small molecule biosensors in eukaryotes (2015) (125)
- A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells (2014) (124)
- Cooperative hydrogen bonding in amyloid formation (2007) (124)
- Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection (2011) (123)
- Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling (2017) (122)
- Programmable design of orthogonal protein heterodimers (2018) (120)
- Symmetry recognizing asymmetry: analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and MHC class I-like ligands. (2003) (120)
- Robust deep learning based protein sequence design using ProteinMPNN (2022) (119)
- Accurate computational design of multipass transmembrane proteins (2018) (118)
- Rapid protein fold determination using unassigned NMR data (2003) (117)
- Protein structure determination from pseudocontact shifts using ROSETTA. (2012) (116)
- Homology modeling using parametric alignment ensemble generation with consensus and energy-based model selection (2006) (116)
- Automated prediction of domain boundaries in CASP6 targets using Ginzu and RosettaDOM (2005) (114)
- Comprehensive computational design of ordered peptide macrocycles (2017) (114)
- Forced Protein Unfolding Leads to Highly Elastic and Tough Protein Hydrogels (2013) (113)
- Protein–protein docking predictions for the CAPRI experiment (2003) (113)
- The sequences of small proteins are not extensively optimized for rapid folding by natural selection. (1998) (112)
- The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction (2010) (112)
- De novo design of protein logic gates (2020) (111)
- NMR characterization of residual structure in the denatured state of protein L. (2000) (111)
- FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants (2015) (110)
- A Double S Shape Provides the Structural Basis for the Extraordinary Binding Specificity of Dscam Isoforms (2008) (109)
- Progress in protein–protein docking: Atomic resolution predictions in the CAPRI experiment using RosettaDock with an improved treatment of side‐chain flexibility (2005) (109)
- Contact order and ab initio protein structure prediction (2002) (107)
- Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle (2019) (107)
- Recurring local sequence motifs in proteins. (1995) (106)
- High-resolution structure of a Shigella type III secretion needle by solid-state NMR and cryo-electron microscopy (2014) (106)
- Improved de novo structure prediction in CASP11 by incorporating coevolution information into Rosetta (2016) (106)
- Critical role of beta-hairpin formation in protein G folding. (2000) (105)
- Sampling bottlenecks in de novo protein structure prediction. (2009) (104)
- Protease pro region required for folding is a potent inhibitor of the mature enzyme (1992) (104)
- Enantioselective enzymes by computational design and in silico screening. (2015) (103)
- A simple physical model for the prediction and design of protein-DNA interactions. (2004) (103)
- Evaluation and ranking of enzyme designs (2010) (102)
- Computational Design of Self-Assembling Cyclic Protein Homo-oligomers (2016) (102)
- Quadrivalent influenza nanoparticle vaccines induce broad protection (2021) (101)
- Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs (2010) (101)
- Exploitation of binding energy for catalysis and design (2009) (100)
- Control over overall shape and size in de novo designed proteins (2015) (100)
- Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant (2011) (99)
- Protein structure prediction in 2002. (2002) (98)
- Structural plasticity of helical nanotubes based on coiled-coil assemblies. (2015) (98)
- Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes (2014) (97)
- Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase (2014) (97)
- Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging (2006) (97)
- CASP6 assessment of contact prediction (2005) (96)
- Density profile consistency and its relation to the transport of trapped versus passing electrons in tokamaks (1998) (96)
- Computational Design of an α-Gliadin Peptidase (2012) (96)
- Community‐wide evaluation of methods for predicting the effect of mutations on protein–protein interactions (2013) (96)
- What has de novo protein design taught us about protein folding and biophysics? (2019) (96)
- Ranking predicted protein structures with support vector regression (2007) (96)
- Exploring folding free energy landscapes using computational protein design. (2004) (95)
- Computational design of trimeric influenza neutralizing proteins targeting the hemagglutinin receptor binding site (2017) (93)
- Hierarchy of structure loss in MD simulations of src SH3 domain unfolding. (1999) (93)
- De novo design of modular and tunable protein biosensors (2021) (93)
- Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope (2011) (93)
- Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution (2012) (93)
- Removing T-cell epitopes with computational protein design (2014) (92)
- Structural and energetic basis of folded protein transport by the FimD usher (2013) (92)
- De novo design of self-assembling helical protein filaments (2018) (91)
- De novo protein design by citizen scientists (2019) (91)
- One contact for every twelve residues allows robust and accurate topology‐level protein structure modeling (2014) (91)
- The Use of Limiting Current to Determine Transport Resistance in PEM Fuel Cells (2006) (91)
- Characterization of the folding energy landscapes of computer generated proteins suggests high folding free energy barriers and cooperativity may be consequences of natural selection. (2004) (90)
- Blind testing of routine, fully automated determination of protein structures from NMR data. (2012) (89)
- Rational design of alpha-helical tandem repeat proteins with closed architectures (2015) (89)
- Computational design of a protein-based enzyme inhibitor. (2013) (89)
- Engineering V-type nerve agents detoxifying enzymes using computationally focused libraries. (2013) (88)
- Origins of catalysis by computationally designed retroaldolase enzymes (2010) (88)
- Advances, interactions, and future developments in the CNS, Phenix, and Rosetta structural biology software systems. (2013) (88)
- A desolvation barrier to hydrophobic cluster formation may contribute to the rate‐limiting step in protein folding (1997) (87)
- High-resolution Structural and Thermodynamic Analysis of Extreme Stabilization of Human Procarboxypeptidase by Computational Protein Design (2007) (87)
- Structural inference of native and partially folded RNA by high-throughput contact mapping (2008) (85)
- Design of protein-binding proteins from the target structure alone (2022) (85)
- Protein structure prediction using Rosetta in CASP12 (2018) (85)
- The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope (2015) (85)
- Computational Design of Transmembrane Pores (2020) (84)
- Improving the performance of rosetta using multiple sequence alignment information and global measures of hydrophobic core formation (2001) (84)
- Improvement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design (2005) (83)
- Computational design of a pH-sensitive IgG binding protein (2013) (83)
- Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens (2020) (83)
- Evolutionary conservation in protein folding kinetics. (2000) (83)
- Accurate computer-based design of a new backbone conformation in the second turn of protein L. (2002) (82)
- Distributions of beta sheets in proteins with application to structure prediction (2002) (82)
- Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals (2006) (82)
- Segmented α-helical coiled-coil structure of the protein giardin from the Giardia cytoskeleton (1988) (82)
- Scoring functions for protein-protein interactions. (2013) (82)
- Conserved residue clustering and protein structure prediction (2003) (82)
- De novo design of tunable, pH-driven conformational changes (2019) (81)
- Resolution-adapted recombination of structural features significantly improves sampling in restraint-guided structure calculation (2011) (81)
- Catalytic mechanism and performance of computationally designed enzymes for Kemp elimination. (2008) (81)
- Transport of photoassimilates (1989) (79)
- Local sequence-structure correlations in proteins. (1996) (79)
- Conversion of monomeric protein L to an obligate dimer by computational protein design (2001) (79)
- Simple physical models connect theory and experiment in protein folding kinetics. (2002) (79)
- Modular and tunable biological feedback control using a de novo protein switch (2019) (79)
- Blind docking of pharmaceutically relevant compounds using RosettaLigand (2009) (77)
- Prediction and design of macromolecular structures and interactions (2006) (77)
- Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions. (2015) (77)
- Contrasting roles for symmetrically disposed beta-turns in the folding of a small protein. (1997) (77)
- Recapitulation of protein family divergence using flexible backbone protein design. (2005) (75)
- Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design. (2015) (74)
- Control of repeat protein curvature by computational protein design (2014) (74)
- Intrinsic disorder drives N-terminal ubiquitination by Ube2w (2014) (74)
- A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly (2013) (73)
- De novo design of a non-local β-sheet protein with high stability and accuracy (2018) (73)
- Temperature and Current Distribution in Thin‐Film Batteries (1999) (73)
- Designed protein logic to target cells with precise combinations of surface antigens (2020) (73)
- A general computational approach for repeat protein design. (2015) (72)
- The dynamic disulphide relay of quiescin sulphydryl oxidase (2012) (72)
- Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions (2016) (72)
- Foldit Standalone: a video game-derived protein structure manipulation interface using Rosetta (2017) (72)
- Computational design of environmental sensors for the potent opioid fentanyl (2017) (71)
- CASD-NMR: critical assessment of automated structure determination by NMR (2009) (71)
- A new hydrogen-bonding potential for the design of protein-RNA interactions predicts specific contacts and discriminates decoys. (2004) (71)
- Scaffolding protein functional sites using deep learning (2022) (71)
- Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration (2017) (71)
- Protein sequence design by conformational landscape optimization (2021) (70)
- A phage display system for studying the sequence determinants of protein folding (1995) (69)
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- Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy (2015) (69)
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- A cell-free platform for the prenylation of natural products and application to cannabinoid production (2019) (68)
- Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings (2011) (68)
- Improved beta‐protein structure prediction by multilevel optimization of nonlocal strand pairings and local backbone conformation (2006) (67)
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- Structures of the B1 domain of protein L from Peptostreptococcus magnus with a tyrosine to tryptophan substitution. (2001) (65)
- Immobilizing affinity proteins to nitrocellulose: a toolbox for paper-based assay developers (2016) (65)
- Improvement of comparative model accuracy by free-energy optimization along principal components of natural structural variation. (2004) (64)
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- Protein contact prediction using metagenome sequence data and residual neural networks (2020) (64)
- Ab Initio Modeling of the Herpesvirus VP26 Core Domain Assessed by CryoEM Density (2006) (64)
- Simplified proteins: minimalist solutions to the 'protein folding problem'. (1998) (64)
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- Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry (2020) (61)
- Understanding protein hydrogen bond formation with kinetic H/D amide isotope effects (2002) (61)
- Protein NMR Structures Refined with Rosetta Have Higher Accuracy Relative to Corresponding X-ray Crystal Structures (2014) (60)
- Superfamily Assignments for the Yeast Proteome through Integration of Structure Prediction with the Gene Ontology (2007) (59)
- Protein structure prediction for the male-specific region of the human Y chromosome. (2004) (59)
- The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles (2013) (59)
- Rational Design of Intercellular Adhesion Molecule-1 (ICAM-1) Variants for Antagonizing Integrin Lymphocyte Function-associated Antigen-1-dependent Adhesion* (2006) (59)
- Heat and Water Transport in Hydrophobic Diffusion Media (2009) (59)
- Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus. (2001) (59)
- Recapitulation and design of protein binding peptide structures and sequences. (2006) (58)
- Proton Conduction in PEM Fuel Cell Cathodes: Effects of Electrode Thickness and Ionomer Equivalent Weight (2010) (58)
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- Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4* (2015) (57)
- Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo. (2020) (57)
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- Prediction of structures of multidomain proteins from structures of the individual domains (2006) (56)
- Local interactions and the optimization of protein folding (1997) (55)
- Structure of the BamC two-domain protein obtained by Rosetta with a limited NMR data set. (2011) (54)
- Circularization changes the folding transition state of the src SH3 domain. (2001) (54)
- Structure of the ultra-high-affinity colicin E2 DNase--Im2 complex. (2012) (54)
- WeFold: A coopetition for protein structure prediction (2014) (53)
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- Profile–profile comparisons by COMPASS predict intricate homologies between protein families (2003) (53)
- Design of Biologically Active Binary Protein 2D Materials (2020) (53)
- Incorporation of evolutionary information into Rosetta comparative modeling (2011) (53)
- Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. (2011) (53)
- Low free energy cost of very long loop insertions in proteins (2003) (53)
- Conservation, Variability and the Modeling of Active Protein Kinases (2007) (52)
- The single helix in protein L is largely disrupted at the rate-limiting step in folding. (1998) (52)
- 2.1 and 1.8 Å Average Cα RMSD Structure Predictions on Two Small Proteins, HP-36 and S15 (2001) (52)
- Simple yet functional phosphate-loop proteins (2018) (51)
- Intercalate Diffusion in Multiphase Electrode Materials and Application to Lithiated Graphite (2012) (51)
- Transient diffusion and migration to a disk electrode (1992) (51)
- Determining crystal structures through crowdsourcing and coursework (2016) (50)
- Evaluation of Models of Electrostatic Interactions in Proteins (2003) (50)
- The effects of mutations on motions of side-chains in protein L studied by 2H NMR dynamics and scalar couplings. (2003) (50)
- Uncertainties in Air Toxics Calculated by the Dispersion Models AERMOD and ISCST3 in the Houston Ship Channel Area (2007) (50)
- The dual role of fragments in fragment‐assembly methods for de novo protein structure prediction (2012) (50)
- Analysis of social gameplay macros in the Foldit cookbook (2011) (50)
- The utility of early end-tidal capnography in monitoring ventilation status after severe injury. (2009) (50)
- A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response (2016) (49)
- Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers (2017) (49)
- The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface : Integrin a IIb b 3 (2009) (49)
- Designed proteins assemble antibodies into modular nanocages (2021) (49)
- Post-translational modification of the N-terminal His tag interferes with the crystallization of the wild-type and mutant SH3 domains from chicken src tyrosine kinase. (2001) (49)
- Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS (2018) (49)
- Analysis of anisotropic side-chain packing in proteins and application to high-resolution structure prediction. (2004) (49)
- The structure, dynamics, and energetics of protein adsorption—lessons learned from adsorption of statherin to hydroxyapatite (2007) (49)
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- Diffusion probabilistic modeling of protein backbones in 3D for the motif-scaffolding problem (2022) (48)
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- Improved chemical shift based fragment selection for CS-Rosetta using Rosetta3 fragment picker (2013) (44)
- Determination of Electrode Sheet Resistance in Cathode Catalyst Layer by AC Impedance (2007) (44)
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- Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation* (2009) (43)
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- Ab initio methods. (2003) (42)
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- Hotspot-centric de novo design of protein binders. (2011) (41)
- Metastable states and folding free energy barriers (1998) (41)
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- High-throughput characterization of protein–protein interactions by reprogramming yeast mating (2017) (41)
- Computational design of closely related proteins that adopt two well-defined but structurally divergent folds (2020) (41)
- Accurate protein structure modeling using sparse NMR data and homologous structure information (2012) (41)
- Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases (2012) (40)
- Automatic structure prediction of oligomeric assemblies using Robetta in CASP12 (2018) (40)
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- The modular structure of the inner-membrane ring component PrgK facilitates assembly of the type III secretion system basal body. (2015) (40)
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- Structural genomics of pathogenic protozoa: an overview. (2008) (39)
- Interactions of the Transmembrane Polymeric Rings of the Salmonella enterica Serovar Typhimurium Type III Secretion System (2010) (39)
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- Applications of contact predictions to structural biology (2017) (39)
- Modulation of Integrin Activation by an Entropic Spring in the β-Knee* (2010) (38)
- Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro (2016) (38)
- CSAR Benchmark Exercise 2013: Evaluation of Results from a Combined Computational Protein Design, Docking, and Scoring/Ranking Challenge (2016) (38)
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- The road to fully programmable protein catalysis (2022) (38)
- Computational design of novel protein binders and experimental affinity maturation. (2013) (37)
- Experimental constraints on transport from dimensionless parameter scaling studies (1998) (37)
- Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study. (2011) (37)
- Thermal diffusivities in DIII-D show evidence of critical gradients (2001) (37)
- Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models (2022) (36)
- Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice (2022) (36)
- Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering (2011) (36)
- First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor (2017) (36)
- Elucidation of N‐linked oligosaccharide structures of recombinant human factor VIII using fluorophore‐assisted carbohydrate electrophoresis (1996) (36)
- Prospects for de novo phasing with de novo protein models (2009) (36)
- Designing Two-Dimensional Protein Arrays through Fusion of Multimers and Interface Mutations. (2015) (35)
- De novo design of transmembrane β barrels (2021) (35)
- Experimental and Theoretical Characterization of Electrode Materials That Undergo Large Volume Changes and Application to the Lithium-Silicon System (2015) (35)
- RosettaDock in CAPRI rounds 6–12 (2007) (35)
- Functional inferences from blind ab initio protein structure predictions. (2001) (34)
- A hybrid NMR/SAXS‐based approach for discriminating oligomeric protein interfaces using Rosetta (2015) (34)
- ProteinGCN: Protein model quality assessment using Graph Convolutional Networks (2020) (34)
- A general expression for bimolecular association rates with orientational constraints (2002) (34)
- De novo design of a non-local beta-sheet protein with high stability and accuracy (2018) (34)
- Modular repeat protein sculpting using rigid helical junctions (2020) (33)
- Sampling and energy evaluation challenges in ligand binding protein design (2017) (33)
- LINEAR GEOMETRICAL MAGNETORESISTANCE EFFECT : INFLUENCE OF GEOMETRY AND MATERIAL COMPOSITION (1999) (33)
- Comparison of quantum mechanics and molecular mechanics dimerization energy landscapes for pairs of ring-containing amino acids in proteins (2004) (33)
- Motif‐directed flexible backbone design of functional interactions (2009) (33)
- Computational design of a homotrimeric metalloprotein with a trisbipyridyl core (2016) (33)
- Centenary Award and Sir Frederick Gowland Hopkins Memorial Lecture. Protein folding, structure prediction and design. (2014) (33)
- An α-Helical Burst in the src SH3 Folding Pathway (2007) (33)
- Improving 3D structure prediction from chemical shift data (2013) (32)
- Intracellular delivery system for antibody-Peptide drug conjugates. (2015) (32)
- Mechanistic Analysis of an Engineered Enzyme that Catalyzes the Formose Reaction (2015) (32)
- High-Resolution Modeling of Transmembrane Helical Protein Structures from Distant Homologues (2014) (32)
- Design of multi-scale protein complexes by hierarchical building block fusion (2021) (32)
- APOBEC2 is a monomer in solution: implications for APOBEC3G models. (2012) (31)
- High‐accuracy refinement using Rosetta in CASP13 (2019) (31)
- Receptor subtype discrimination using extensive shape complementary designed interfaces (2019) (30)
- Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. (2014) (30)
- Nonlinear development of the two ion beam instability (1973) (30)
- Self-Assembling 2D Arrays with de Novo Protein Building Blocks. (2019) (30)
- Crystal structure of a monomeric retroviral protease solved by protein folding game players (2012) (30)
- Front Cover: Improved Free‐Energy Landscape Quantification Illustrated with a Computationally Designed Protein–Ligand Interaction (ChemPhysChem 1/2018) (2018) (30)
- Isotope signatures allow identification of chemically cross-linked peptides by mass spectrometry: a novel method to determine interresidue distances in protein structures through cross-linking. (2010) (30)
- Trapping a transition state in a computationally designed protein bottle (2015) (29)
- Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design. (2018) (29)
- Rational design of α-helical tandem repeat proteins with closed architectures (2015) (29)
- Crystal structure of XMRV protease differs from the structures of other retropepsins (2010) (28)
- Modeling Disordered Regions in Proteins Using Rosetta (2011) (28)
- Complementary Chimeric Isoforms Reveal Dscam1 Binding Specificity In Vivo (2012) (28)
- CASP11 refinement experiments with ROSETTA (2016) (28)
- Mis-translation of a computationally designed protein yields an exceptionally stable homodimer: implications for protein engineering and evolution. (2006) (28)
- Mapping of IFN-beta epitopes important for receptor binding and biologic activation: comparison of results achieved using antibody-based methods and alanine substitution mutagenesis. (2001) (27)
- Corrigendum: Design of a hyperstable 60-subunit protein icosahedron (2016) (27)
- Design of proteins presenting discontinuous functional sites using deep learning (2020) (27)
- Increased Diels-Alderase Activity through Foldit Player Guided Backbone Remodeling (2012) (27)
- Mutations Designed to Destabilize the Receptor-Bound Conformation Increase MICA-NKG2D Association Rate and Affinity* (2007) (27)
- Deep learning and protein structure modeling (2022) (27)
- A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila* (2007) (27)
- O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity (2021) (27)
- Peptide solvation and H-bonds (2006) (26)
- Efficient minimization of angle‐dependent potentials for polypeptides in internal coordinates (2003) (26)
- Predictive model for depressurization-induced blistering of type IV tank liners for hydrogen storage (2017) (26)
- Plants against Helicobacter pylori to combat resistance: An ethnopharmacological review (2020) (26)
- High-resolution structure of a retroviral protease folded as a monomer (2011) (26)
- De novo protein design by deep network hallucination (2021) (26)
- Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit (2021) (26)
- ION-WAVE ECHOES. (1968) (26)
- Searching for folded proteins in vitro and in silico. (2004) (26)
- Modeling Two-Phase Water Transport in Hydrophobic Diffusion Media for PEM Fuel Cells (2011) (25)
- Elicitation of broadly protective immunity to influenza by multivalent hemagglutinin nanoparticle vaccines (2020) (25)
- Plasma production with rotating ion cyclotron waves excited by Nagoya Type-III antennas in RFC-XX (1985) (25)
- Protein tertiary structure prediction and refinement using deep learning and Rosetta in CASP14 (2021) (25)
- Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2 (2002) (24)
- Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression (2015) (24)
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- Hallucinating symmetric protein assemblies (2022) (24)
- Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion (2020) (24)
- Advances in Rosetta protein structure prediction on massively parallel systems (2008) (24)
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- The fumarate sensor DcuS: progress in rapid protein fold elucidation by combining protein structure prediction methods with NMR spectroscopy. (2005) (23)
- VaxCelerate II: Rapid development of a self-assembling vaccine for Lassa fever (2014) (23)
- High-resolution structural validation of the computational redesign of human U1A protein. (2006) (23)
- De novo carborane-containing macrocyclic peptides targeting human EGFR. (2019) (23)
- Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2. (2002) (23)
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- Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease (2021) (22)
- Dependent‐Variable Transformation for the Treatment of Diffusion, Migration, and Homogeneous Reactions Application to a Corroding Pit (1993) (21)
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- Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein (2019) (21)
- Rosetta in CAPRI rounds 13–19 (2010) (21)
- Force Field Optimization Guided by Small Molecule Crystal Lattice Data Enables Consistent Sub-Angstrom Protein-Ligand Docking. (2021) (21)
- Multivalent Display of Antifreeze Proteins by Fusion to Self-Assembling Protein Cages Enhances Ice-Binding Activities. (2016) (21)
- Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1 (2021) (21)
- Active Site Plasticity of a Computationally Designed Retro‐Aldolase Enzyme (2014) (21)
- EFFICIENT MODULATION COUPLING BETWEEN ELECTRON AND ION RESONANCES IN MAGNETOACTIVE PLASMAS. (1970) (21)
- AN ANALYTIC SOLUTION FOR THE MICRODISK ELECTRODE AND ITS USE IN THE EVALUATION OF CHARGE-TRANSFER RATE CONSTANTS (1990) (21)
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- Expanding the Scope of Lithium Coordination Chemistry by Placing Sodium Nearby: A Mixed Lithium-Sodium Benzyl Compound Having TMEDA-Chelated Li+ Cations in an Unprecedented Tetrameric Environment (1994) (21)
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- Isostructural potassium and sodium di-nitrogen functionalized amides: Syntheses and crystal structures of [Ph(2-Pyr)NK·TMEDA]2 and [Me(2-Pyr)NNa·TMEDA]2 (1991) (20)
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- TraDIS-Xpress: a high-resolution whole-genome assay identifies novel mechanisms of triclosan action and resistance (2020) (20)
- Achillea millefolium L. ethyl acetate fraction induces apoptosis and cell cycle arrest in human cervical cancer (HeLa) cells (2020) (20)
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- CO2 interferometer operation in doublet III (1980) (19)
- Disentangling Rotational Dynamics and Ordering Transitions in a System of Self-Organizing Protein Nanorods via Rotationally Invariant Latent Representations. (2021) (19)
- Accurate prediction of nucleic acid and protein-nucleic acid complexes using RoseTTAFoldNA (2022) (18)
- Thermodynamic Model for Substitutional Materials: Application to Lithiated Graphite, Spinel Manganese Oxide, Iron Phosphate, and Layered Nickel-Manganese-Cobalt Oxide (2018) (18)
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- Engineered Biosensors from Dimeric Ligand-Binding Domains. (2018) (18)
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- Frontiers in Application of Impedance Diagnostics to H2-Fed Polymer Electrolyte Fuel Cells (2008) (18)
- A computational method for design of connected catalytic networks in proteins (2019) (18)
- Phytochemical Investigation and Radical Scavenging Activity of Wastes of Some Grape Varieties Grown in Egypt (2013) (18)
- Anti-Inflammatory and Antioxidant Activities of Rhubarb Roots Extract (2016) (18)
- Reducing Nonlinear Systems of Transport Equations to Laplace's Equation (1993) (18)
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- Single Layers of Attention Suffice to Predict Protein Contacts (2020) (17)
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- Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIβ binding protein 1 (2009) (16)
- Feature Selection Methods for Improving Protein Structure Prediction with Rosetta (2007) (16)
- Structure similarity measure with penalty for close non-equivalent residues (2009) (16)
- Computational design of a synthetic PD-1 agonist (2021) (16)
- Structure of Lmaj006129AAA, a hypothetical protein from Leishmania major. (2006) (16)
- Contributions of solvent-solvent hydrogen bonding and van der Waals interactions to the attraction between methane molecules in water. (1998) (16)
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- Ecology and the science of small-scale fisheries: A synthetic review of research effort for the Anthropocene (2021) (13)
- Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide‐rich de novo designed peptides (2018) (13)
- Suppression of flute instability in an axisymmetric double-cusp plasma by RF ponderomotive force (1984) (13)
- Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations (2020) (13)
- Structurally Mapping Endogenous Heme in the CcmCDE Membrane Complex for Cytochrome c Biogenesis. (2018) (13)
- Thermodynamics, stress, and Stefan-Maxwell diffusion in solids: application to small-strain materials used in commercial lithium-ion batteries (2015) (12)
- Design and characterization of stabilized derivatives of human CD4D12 and CD4D1. (2011) (12)
- Large-scale design and refinement of stable proteins using sequence-only models (2021) (12)
- An integrated device for the rapid and sensitive detection of the influenza hemagglutinin. (2019) (12)
- Coordinate‐space formulation of polymer lattice cluster theory (1993) (12)
- Modeling Overcharge at Graphite Electrodes: Plating and Dissolution of Lithium (2019) (12)
- Battery State Estimator Based on a Finite Impulse Response Filter (2013) (12)
- Improving de novo Protein Binder Design with Deep Learning (2022) (11)
- Simultaneous Transport of Water and Adsorbed Solutes Through Soil Under Transient Flow Conditions (1975) (11)
- Accelerated electron transport from photosystem I to redox partners by covalently linked ferredoxin. (2013) (11)
- Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes (2014) (11)
- Building de novo cryo-electron microscopy structures collaboratively with citizen scientists (2019) (11)
- Cyclic oligomer design with de novo αβ‐proteins (2017) (11)
- Template‐based modeling by ClusPro in CASP13 and the potential for using co‐evolutionary information in docking (2019) (11)
- Redesigning the specificity of protein-DNA interactions with Rosetta. (2014) (11)
- Constructing Structural Profiles for Protein Torsion Angle Prediction (2015) (11)
- Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants (2022) (11)
- De novo design of a homo-trimeric amantadine-binding protein (2019) (11)
- 2.1 and 1.8 A average C(alpha) RMSD structure predictions on two small proteins, HP-36 and s15. (2001) (11)
- Role of backbone strain in de novo design of complex α/β protein structures (2021) (11)
- Protein oligomer modeling guided by predicted interchain contacts in CASP14 (2021) (10)
- A perturbative solution of the drift kinetic equation yields pinch type convective terms in the particle and energy fluxes for strong electrostatic turbulence (2004) (10)
- Use of the drift kinetic equation to describe electrostatic turbulent transport (2002) (10)
- Accurate de novo design of membrane-traversing macrocycles (2022) (10)
- Two common structural motifs for TCR recognition by staphylococcal enterotoxins (2016) (10)
- De novo design of transmembrane beta-barrels (2021) (10)
- Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus (2014) (10)
- Measurements of Ion Acoustic Fluctuations in a Low Density Plasma by Scattering of Pulsed CO_sub.2 Laser Light (1975) (10)
- Deep learning enables the atomic structure determination of the Fanconi Anemia core complex from cryoEM (2020) (9)
- Super-enhancer-based identification of a BATF3/IL-2R−module reveals vulnerabilities in anaplastic large cell lymphoma (2021) (9)
- Measurements of Atomic Hydrogen-Density Profiles in the RFC-XX-M Machine Using Laser Fluorescence Spectroscopy at the Hα Transition (1985) (9)
- Density profile consistency, particle pinch, and cold pulse propagation in DIII-D (1997) (9)
- Reaction distribution in a corroding pit (1993) (9)
- Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs (2022) (9)
- Progress in AB Initio Protein Structure Prediction (2002) (9)
- MARINE ALGAL STEROL HYDROCARBON WITH ANTI-INFLAMMATORY, ANTICANCER AND ANTI-OXIDANT PROPERTIES (2016) (9)
- Author response: Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information (2014) (9)
- Structure Predictions on Two Small Proteins , HP-36 and S 15 (9)
- Mathematical analysis of potentiometric oxygen sensors for combustion-gas streams (1994) (9)
- Multivalent designed proteins protect against SARS-CoV-2 variants of concern (2021) (9)
- F-domain valency determines outcome of signaling through the angiopoietin pathway (2020) (9)
- Airway Management in Emergencies. (2009) (9)
- Multi-Species, Multi-Reaction Model for Porous Intercalation Electrodes: Part I. Model Formulation and a Perturbation Solution for Low-Scan-Rate, Linear-Sweep Voltammetry of a Spinel Lithium Manganese Oxide Electrode (2018) (9)
- Structures and disulfide cross‐linking of de novo designed therapeutic mini‐proteins (2018) (8)
- De novo design of transmembrane β-barrels (2020) (8)
- De novo design of modular and tunable allosteric biosensors (2020) (8)
- Improved Free-Energy Landscape Quantification Illustrated with a Computationally Designed Protein-Ligand Interaction. (2018) (8)
- Robust de novo design of protein binding proteins from target structural information alone (2021) (8)
- In-situ solid hydrogen pellet experiments in Doublet III (1981) (8)
- Computational design of mixed chirality peptide macrocycles with internal symmetry (2020) (8)
- Limiting Current as a Tool to Study Oxygen Transport in PEM Fuel Cells (2013) (8)
- Comparison of gyrokinetic stability code calculated critical ion temperature gradients and growth rates to DIII-D measured gradients and diffusivities (2003) (8)
- Dependence of Electrode Proton Resistivity on Electrode Thickness and Ionomer Equivalent Weight in Cathode Catalyst Layer in PEM Fuel Cell (2008) (8)
- Introduction of a polar core into the de novo designed protein Top7 (2016) (7)
- Multi-Species, Multi-Reaction Model for Porous Intercalation Electrodes: Part II. Model-Experiment Comparisons for Linear-Sweep Voltammetry of Spinel Lithium Manganese Oxide Electrodes (2019) (7)
- STEROLS BIOACTIVITY OF RUTA GRAVEOLENS L. AND MURRAYA PANICULATA L. (2017) (7)
- Elfin: An algorithm for the computational design of custom three-dimensional structures from modular repeat protein building blocks. (2017) (7)
- From folding towards function (2002) (7)
- Detection of Protein Coding Sequences Using a Mixture Model for Local Protein Amino Acid Sequence (2000) (7)
- Ion-dependent protein–surface interactions from intrinsic solvent response (2021) (7)
- Similarities and Differences between Potential-Step and Impedance Methods for Determining Diffusion Coefficients of Lithium in Active Electrode Materials (2013) (7)
- Diffusion‐Induced Stress within Core–Shell Structures and Implications for Robust Electrode Design and Materials Selection (2015) (7)
- Electron density redistribution accounts for half the cooperativity of alpha helix formation. (2006) (7)
- Swelling and Elastic Deformation of Lithium-Silicon Electrode Materials (2016) (7)
- The role of charge separation in the response of electrochemical systems (1998) (7)
- PRISM: application to the solution of two protein structures. (1993) (7)
- A Simple Formula Describing Impedance Artifacts due to the Size and Surface Resistance of a Reference-Electrode Wire in a Thin-Film Cell (2017) (7)
- The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach (2021) (7)
- The influence of surface inhomogeneity on the overcharge and lithium plating of graphite electrodes (2019) (7)
- Designed protein aggregates entrapping carbon nanotubes for bioelectrochemical oxygen reduction (2016) (7)
- Transferrin receptor targeting by de novo sheet extension (2021) (7)
- Determination of the structural parameters for the van der Waals complexes between N2 and ClF molecules (1992) (7)
- Isolating Conformers to Assess Dynamics of Peptidic Catalysts Using Computationally Designed Macrocyclic Peptides. (2021) (7)
- De novo design of luciferases using deep learning (2023) (7)
- Erratum: Native protein sequences are close to optimal for their structures (Proceedings of the National Academy of Sciences of the United States of America (September 12, 2000) 97 (10383-10388)) (2000) (7)
- Stability studies of a hollow plasma in the double cusp experiment (1984) (7)
- Parallelization and performance characterization of protein 3D structure prediction of Rosetta (2006) (6)
- Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold. (2018) (6)
- Multimerization of an Alcohol Dehydrogenase by Fusion to a Designed Self-Assembling Protein Results in Enhanced Bioelectrocatalytic Operational Stability. (2019) (6)
- Sampling of structure and sequence space of small protein folds (2021) (6)
- Theory and Simulation of Solid‐Electrolyte Wide‐Range Sensors for Combustion‐Gas Streams (1996) (6)
- De novo design of immunoglobulin-like domains (2021) (6)
- Structure-Based Design of Non-Natural Amino Acid Inhibitors of Amyloid Fibrillation (2014) (6)
- Fabrication and Characterization of Lithium-Silicon Thick-Film Electrodes for High-Energy-Density Batteries (2017) (6)
- Kinetics and Kinetically Limited Performance in PEMFCs and DMFCs with State-of-the-Art Catalysts (2008) (6)
- Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks (2020) (5)
- De novo design and directed folding of disulfide-bridged peptide heterodimers (2022) (5)
- Pulsed plasmoid electric thruster (1991) (5)
- Rapid Online Buffer Exchange: A Method for Screening of Proteins, Protein Complexes, and Cell Lysates by Native Mass Spectrometry (2019) (5)
- Grape Seeds Extract as Brain Food: A Review (2017) (5)
- Interpreting neural networks for biological sequences by learning stochastic masks (2021) (5)
- Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks (2021) (5)
- The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice (2022) (5)
- Design of biologically active binary protein 2D materials (2021) (5)
- dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region (2022) (5)
- Natural and designed proteins inspired by extremotolerant organisms can form condensates and attenuate apoptosis in human cells (2021) (4)
- Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock (2022) (4)
- Ultrapotent miniproteins targeting the receptor-binding domain protect against SARS-CoV-2 infection and disease in mice (2021) (4)
- De novo design of obligate ABC-type heterotrimeric proteins (2022) (4)
- Corrigendum: Determining crystal structures through crowdsourcing and coursework (2016) (4)
- Convective Diffusion to a Microdisk Sensor Subject to Uniform Shear Flow (1996) (4)
- A covariation analysis reveals elements of selectivity in quorum sensing systems (2021) (4)
- Corrigendum: Atomic model of the type III secretion system needle (2012) (4)
- A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy (2022) (4)
- De novo design of high-affinity protein binders to bioactive helical peptides (2022) (4)
- De novo design of tyrosine and serine kinase-driven protein switches (2021) (4)
- Crystallization and preliminary X-ray diffraction studies of mutants of B1 IgG-binding domain of protein L from Peptostreptococcus magnus. (2000) (4)
- Epistasis on the stability landscape of de novo TIM barrels explored by a modular design approach (2020) (4)
- Amyloid beta peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Abeta mediated toxicity in vitro (2019) (4)
- POTENTIAL EFFECTS OF GLIMEPIRIDE AND A HERBAL MIXTURE ON HYPERGLYCAEMIA, HYPERCHOLESTEROLAEMIA AND OXIDATIVE STRESS (2020) (4)
- Computational Protein Design for Synthetic Biology (2013) (4)
- Electroanalytical Methods Utilizing Small Signal Current or Potential Excitations for the Characterization of Porous Electrodes Comprising Insertion Materials (2013) (4)
- Publisher's Note: Proton Conduction and Oxygen Reduction Kinetics in PEM Fuel Cell Cathodes: Effects of Ionomer-to-Carbon Ratio and Relative Humidity [ J. Electrochem. Soc. , 156 , B970 (2009) ] (2009) (4)
- Author Correction: A cell-free platform for the prenylation of natural products and application to cannabinoid production (2019) (4)
- Sentinel cells enable genetic detection of SARS-CoV-2 Spike protein (2021) (4)
- Quality Assessment of Low Free-Energy Protein Structure Predictions (2005) (4)
- Cloning, expression, purification, crystallization and preliminary X-ray diffraction data of the Pyrococcus horikoshii RadA intein. (2011) (3)
- Rotational dynamics and transition mechanisms of surface-adsorbed proteins (2022) (3)
- Conditional Recruitment to a DNA-Bound CRISPR-Cas Complex Using a Colocalization-Dependent Protein Switch. (2020) (3)
- Exploring particle dynamics during self-organization processes via rotationally invariant latent representations (2020) (3)
- Special Issue: Special Issue on Protein Evolution and Design July 2016 (2016) (3)
- Folding and binding (1991) (3)
- Smoothing Methods for Numerical Differentiation to Identify Electrochemical Reactions from Open-Circuit-Potential Data (2018) (3)
- Characterizing disease-associated human proteins without available protein structures or homologues (2021) (3)
- Interpreting Potts and Transformer Protein Models Through the Lens of Simplified Attention (2021) (3)
- Modeling Overcharge at Lithiated-Graphite Porous Electrodes: Plating and Dissolution of Lithium (2020) (3)
- Template Scoring Methods for Protein Torsion Angle Prediction (2015) (3)
- Symmetry Recognizing Asymmetry : Analysis of the Interactions between the C-Type Lectin-like Immunoreceptor NKG 2 D and MHC Class (2003) (3)
- Heterodyne Detection of Pulsed Co2 Laser Light Scattered from Ion Acoustic Waves in a Plasma (1977) (3)
- De novo design of transmembrane b barrels (2021) (3)
- Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes (2022) (3)
- RoseTTAFold: The first release of RoseTTAFold (2021) (2)
- Publisher Correction: Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets (2018) (2)
- Protein Torsion Angle Class Prediction by a Hybrid Architecture of Bayesian and Neural Networks (2012) (2)
- Learning a force field from small-molecule crystal lattice predictions enables consistent sub-Angstrom protein-ligand docking (2020) (2)
- recurrent amino acid sequence patterns Three-dimensional structures and contexts associated with (2002) (2)
- Computer Designed PRC2 Inhibitor, EBdCas9, Reveals Functional TATA boxes in Distal Promoter Regions (2020) (2)
- Bacterial expression and protein purification of mini-fluorescence-activating proteins (2021) (2)
- Correction for Lee et al., RNA design rules from a massive open laboratory (2015) (2)
- A Monte Carlo Study of the Uncertainties in Predictions by ISC3ST and AERMOD of Annual Average Benzene and 1,3-Butadiene Concentrations around the Houston Ship Channel (2004) (2)
- RECENT CHALLENGES IN TUBERCULOSIS TREATMENTS: A REVIEW (2020) (2)
- ModelCIF: An extension of PDBx/mmCIF data representation for computed structure models (2022) (2)
- Full title Improved de novo Structure Prediction in CASP 11 by Incorporating Co-evolution Information into Rosetta Short title Structure Prediction using Co-evolution (2015) (2)
- Hallucinating protein assemblies (2022) (2)
- Self-assembly–based posttranslational protein oscillators (2020) (2)
- On the role of a conserved, potentially helix-breaking residue in the tRNA-binding alpha-helix of archaeal CCA-adding enzymes. (2008) (2)
- Ab initio structure prediction (2005) (2)
- Tests of an ICRH Resonant Cavity Launcher with Faraday Shield (1986) (2)
- Low Frequency Impedance of Polymer Electrolyte Fuel Cells (2006) (2)
- Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system (2021) (2)
- Experimental and Theoretical Examination of Low-Current Overcharge at Lithiated-Graphite Porous Electrodes (2020) (2)
- De novo design of protein homodimers containing tunable symmetric protein pockets (2022) (2)
- Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection (2022) (2)
- Competitive Displacement of De Novo Designed HeteroDimers Can Reversibly Control Protein–Protein Interactions and Implement Feedback in Synthetic Circuits (2022) (2)
- Human iPSC Derived Enamel Organoid Guided by Single-Cell Atlas of Human Tooth Development (2022) (1)
- Reaction distribution over a nodule in a thin-film battery (1995) (1)
- Generation of Potent and Stable GLP-1 Analogues Via "Serine Ligation". (2022) (1)
- Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins (2023) (1)
- De novo design of modular peptide-binding proteins by superhelical matching (2022) (1)
- Top-down design of protein nanomaterials with reinforcement learning (2022) (1)
- De Novo Design of Novel Covalent Constrained Meso-size Peptide Scaffolds with Unique Tertiary Structures (2017) (1)
- Computational design of nanoscale rotational mechanics in de novo protein assemblies (2021) (1)
- Rapid and Sensitive Detection of Antigen from SARS-CoV-2 Variants of Concern by a Multivalent Minibinder-Functionalized Nanomechanical Sensor (2022) (1)
- Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains (2022) (1)
- Capsid model of M13 bacteriophage virus from Magic-angle spinning NMR and Rosetta modeling (2015) (1)
- The Combined Influence of Interfacial Reaction Resistance and Fluid Flow on Microelectrode Sensors (1996) (1)
- A Computationally Designed Protein-Ligand Interaction is Mechanically Robust (2017) (1)
- Molecular replacement and model-building using distant homology models as templates (2012) (1)
- Molecular Mechanisms of RNA Interference (2016) (1)
- REMOTE PLASMA CONTROL, HEATING, MEASUREMENTS OF ELECTRON DISTRIBUTION, AND TRAPPED PARTICLES BY NONLINEAR ELECTROMAGNETIC INTERACTIONS. (1971) (1)
- Randomized gates eliminate bias in sort‐seq assays (2022) (1)
- Accurate Computational Design of 3D Protein Crystals (2022) (1)
- An R-Helical Burst in the src SH 3 Folding Pathway (2006) (1)
- Alignment of Au nanorods along de novo designed protein nanofibers studied with automated image analysis. (2021) (1)
- Publisher Correction: Modular and tunable biological feedback control using a de novo protein switch (2020) (1)
- P05-09. 4e10 epitope-scaffolds mimic the antibody-bound epitope conformation and block neutralization by sera from rare HIV+ individuals (2009) (1)
- Self-assembly based post-translational protein oscillators (2020) (1)
- Computational protein design with rosetta (2008) (1)
- Application of a helicopter mathematical model to the Langley differential maneuvering simulator for use in a helicopter/fighter evasive maneuver study (1976) (1)
- Slow Current or Potential Scanning of Battery Porous Electrodes: Generalized Perturbation Solution and the Merits of Sinusoidal Current Cycling (2021) (1)
- EVALUATION OF ANTIOXIDANT, ANTI-INFLAMMATORY, ANTI-ALZHEIMER’S AND ANTICANCER ACTIVITIES OF TAONIA ATOMARIA (2016) (1)
- Improved chemical shift based fragment selection for CS-Rosetta using Rosetta3 fragment picker (2013) (1)
- Stapled β-Hairpins Featuring 4-Mercaptoproline. (2021) (1)
- THE ROAD TO CLOSURE FOR THE LOVELACE RESPIRATORY RESEARCH INSTITUTE (2005) (1)
- Crystal structure of a computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein (2014) (1)
- Post Situ neutron and gamma radiation damage tests on different quartz types (2016) (1)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR494. (2014) (1)
- Author response: Precise assembly of complex beta sheet topologies from de novo designed building blocks (2015) (1)
- Author response: Large-scale determination of previously unsolved protein structures using evolutionary information (2015) (1)
- VaxCelerate: the use of MTBhsp70-avidin as an adjuvant to rapidly generate self-assembling vaccines with biotinylated, antigen-specific peptides targeting emerging pathogens. (VAC6P.941) (2014) (1)
- Apo Structure of the De Novo PD-1 Binding Miniprotein GR918.2 (2020) (1)
- Author Correction: Design of biologically active binary protein 2D materials (2021) (1)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR94 (2012) (1)
- Connectivity and the phase problem in macromolecular crystallography (1993) (1)
- Importance of Substrate-Particle Repulsion for Protein-Templated Assembly of Metal Nanoparticles. (2021) (1)
- In silico designed of an improved Kemp eliminase KE70 mutant by computational design and directed evolution (2011) (1)
- Editorial (2016) (1)
- Regulatory DNA keyholes enable specific and persistent multi-gene expression programs in primary T cells without genome modification (2020) (1)
- High-Resolution Structural Modeling of Voltage-Dependent Conformational Changes in the Voltage Sensor of NaChBac (2011) (1)
- Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein (2022) (1)
- High-Throughput Characterization of Protein-Protein Interactions by Reprogramming Yeast Mating (2017) (0)
- Abstract B073: Protein nanoparticles for controllable T cell activation (2016) (0)
- De Novo Design of Protein Binders: Targeting Human IgG (Fc) (2012) (0)
- De novo design of energy transfer proteins housing excitonically coupled chlorophyll special pairs (2023) (0)
- A computationally designed hemagglutinin stem-binding protein provides in vivo protection from influenza in the ferret model. (2016) (0)
- P12-12. Analysis of antibody and B cell responses following inoculation with computationally designed HIV-1 2F5 epitope scaffold proteins (2009) (0)
- 4427 Angiopoietin F-domain valency determines outcome of Tie2 receptor engagement and accelerates angiogenesis in tissue regeneration (2020) (0)
- Abstract 5573: A high-affinity Optide (optimized peptide) inhibitor of the Hippo pathway’s YAP-TEAD interaction (2017) (0)
- De novo Design of a Highly Specific Inhibitor of Integrin Αvβ6 for Pulmonary Fibrosis (2021) (0)
- A Geometric Filter for Unbound Protein-Protein Docking ∗ (2005) (0)
- Design and Characterization of Stabilized Derivatives of Human CD 4 D 12 and CD 4 D 1 (2011) (0)
- Expression of de novo disulfide-rich proteins with α, β-hydrolase-type folds (2015) (0)
- Abstract 2971: Optides (optimized knottin peptides) computationally designed to target the oncogenic HIPPO pathway (2016) (0)
- 3P021 Refolding of src SH3 domain protein by CD-stopped-flow at 4℃ (2004) (0)
- The role of I ; ‘ 0 regions in protein folding (2004) (0)
- Surface assisted self-assembly of designed helix repeated protein (2018) (0)
- Cryo-EM structure of a de novo designed 16-helix transmembrane nanopore, TMHC8_R. (2020) (0)
- Studying the Structural Origins of Microtubule Dynamic Instability through Combining Computational Modeling and cryoEM (2014) (0)
- Protein Scaffolding for Small Molecule Catalysts (2014) (0)
- Adventures in the Engineering of the Small Laccase (SLAC) from Streptomyces Coelicolor for Incorporation into Enzymatic Biofuel Cell Cathodes (2014) (0)
- Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups (2022) (0)
- protein folding A phage display system for studying the sequence determinants of (2002) (0)
- Influenza hemagglutinin: kinetic control of protein function In response to decreased pH, influenza hemagglutinin changes to a more stable conformation. Such changes, which can be controlled thermodynamically or kinetically, are the method by which many biological 'switches' are thrown. (1994) (0)
- New Approach Builds Better Proteins Inside a Computer (2007) (0)
- High-Resolution Structural Modeling of Ion Channel Pore-Forming Domains Using Rosetta (2010) (0)
- Secretion System Serovar Typhimurium Type III Salmonella enterica of the Interactions of the Transmembrane Polymeric Rings 2010 (2010) (0)
- Symmetry-Based Design and Structure of Self-Assembling Protein Cages and Nanomaterials (2014) (0)
- Parallelized identification of on- and off-target protein interactions. (2020) (0)
- 1 A MONTE CARLO STUDY OF UNCERTAINTIES IN BENZENE AND 1 , 3-BUTADIENE CONCENTRATIONS CALCULATED BY AERMOD AND ISC IN THE HOUSTON SHIP CHANNEL AREA (2005) (0)
- High-Throughput Protein Design Reveals Quantitative Protein Stability Requirements (2017) (0)
- Milk Thistle Seeds Powder: A Potential Source of High Value-Added for Functional Pan Bread (2021) (0)
- Study of the Protective Effects of Summer Savory against Multiple Organ Damage Induced by Lead Acetate in Rats (2019) (0)
- BP2_disulf: A Novel Therapeutic for Idiopathic Pulmonary Fibrosis Improves Clinically Relevant Endpoints in Bleomycin Mouse Model (0)
- Erratum: Slow Current or Potential Scanning of Battery Porous Electrodes: Generalized Perturbation Solution and the Merits of Sinusoidal Current Cycling [ J. Electrochem. Soc., 168, 050526 (2021)] (2021) (0)
- 3.1 Nonlinear Collisionless Interaction Between Electron and Ion Modes and Feedback Stabilization in Fusion Plasmas (1970) (0)
- (Invited) Thermodynamics, Stress, and Stefan-Maxwell Diffusion in Solids: Application to Small-Strain Materials Used in Commercial Lithium-Ion Batteries (2016) (0)
- Controlling i.c. engine turbocharger compressor surge using EGR flow (2006) (0)
- Real time two wavelength interferometer system (1982) (0)
- Gas diffusion layer can be positioned between an electrode and a flow field in a PEM fuel cell (2009) (0)
- Invited) Limiting Current As a Tool to Study Oxygen Transport in PEM Fuel Cells (2015) (0)
- TRANSPORT AND TURBULENCE (1999) (0)
- Reduced Order Models Derived from Perturbation Solutions and Applied to a Lithium Ion Intercalation Electrode (2022) (0)
- The effect of turbulent stresses on the experimental determination of a thermal diffusivity due to turbulent transport (2002) (0)
- Structural and mechanistic variations in the alkali metal amide chemistry of dibenzylamine (1993) (0)
- Publisher's Note: Proton Conduction and Oxygen Reduction Kinetics in PEM Fuel Cell Cathodes: Effects of Ionomer-to-Carbon Ratio and Relative Humidity (2009) (0)
- CouplingAnalysisforthe ICRF Resonant Cavity Launcheron DJII-D (1987) (0)
- Discharge initiation with an in-situ hydrogen pellet in Doublet III (1981) (0)
- Properties of diverted plasmas with magnetically expanded flux surfaces (1980) (0)
- Design of long pulse heating systems for Doublet III-D (1984) (0)
- Plasma Confinement by a Radio Frequency Plugging Potential in an Axisymmetric Mirror-Cusp Device (1986) (0)
- EFFECTS OF PARTICLE FUELlNlG AND DISCHARGES PLASMA WALL INTERACTIONS ON DIII-D (2007) (0)
- Comparison of Data and Modeling Results for an Optical Li-Ion Cell (2010) (0)
- Cation Mixing and Capacity Loss in Li||Ni0.6Mn0.2Co0.2O2 Cells: Experimental Investigation and Application of the Multi-Site, Multi-Reaction Model (2022) (0)
- A system for controlling a turbocharger compressor surge (2006) (0)
- Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells (2022) (0)
- Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg (2019) (0)
- Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic (2019) (0)
- Title Structures and disulfide cross-linking of de novo designed therapeutic mini-proteins Permalink (2018) (0)
- A de novo designed transmembrane nanopore, TMH4C4 (2020) (0)
- De novo design of potent and selective mimics of IL-2 and IL-15 (2019) (0)
- Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds. (2023) (0)
- High resolution, high throughput protein structure prediction using IBM Blue Gene supercomputers: predicting CASP targets in record time (2006) (0)
- De novo design of potent and selective mimics of IL-2 / IL-15 1 (2018) (0)
- Dataset For Article: "Massively Parallel De Novo Protein Design For Targeted Therapeutics", Doi: 10.1038/Nature23912 (2017) (0)
- De novo design of BMP mimics. (2023) (0)
- Abstract 1075: Conditionally activede novoIL-2 cytokine mimetics for targeted immunotherapy:de novosplit technology (2020) (0)
- De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy. Nature Chemical Biology, 12(1), 29-34. (2015) (0)
- Lawrence Berkeley National Laboratory Recent Work Title De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity Permalink (0)
- Improving 3D structure prediction from chemical shift data (2013) (0)
- Complex Structure of the Activation Domain of Gcn4 bound to the Mediator Co-Activator Domain of Gal11/Med15 (2010) (0)
- Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry (2020) (0)
- Crystal structure of computationally designed protein 2DS25.5 in complex with the human Transferrin receptor ectodomain (0)
- Crystal structure of computationally designed protein 2DS25.1 in complex with the human Transferrin receptor ectodomain (0)
- Structure of the complex of the central activation doamin of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15 (2012) (0)
- Minimized average structure of GDP-bound dynamic microtubules (2014) (0)
- Towards a synthetic post-translational protein oscillator (2020) (0)
- Crystal structure of P8C9 bound to CK2alpha (2021) (0)
- Energy minimized average structure of Microtubules stabilized by GmpCpp (2014) (0)
- Organizing cell-free expressed membrane proteins in synthetic membranes using lipid-protein interactions (2022) (0)
- 1769-Pos Board B499 Tubulin Heterodimers Reversibly Dissociate with Moderate Kinetics as Demonstrated using SedimentationVelocity Analytical Ultracentrifugation (2014) (0)
- Minimized average structure of microtubules stabilized by taxol (2014) (0)
- Solution NMR Structure of De novo designed protein, Northeast Structural Genomics Consortium (NESG) Target OR459 (2014) (0)
- Crystal structure of the F5/8 type C domain of Q5LFR2_BACFN protein from Bacteroides fragilis. Northeast Structural Genomics Consortium Target BfR258E (2010) (0)
- Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T32-28 (2014) (0)
- CRYSTAL STRUCTURE OF ACYLENZYME INTERMEDIATE OF DE NOVO DESIGNED CYSTEINE ESTERASE ECH13, Northeast Structural Genomics Consortium Target OR51 (2011) (0)
- Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR43 (2012) (0)
- Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR404 (2013) (0)
- Crystal Structure of de Novo design of cystein esterase ECH13 at the resolution 1.6A, Northeast Structural Genomics Consortium Target OR51 (2011) (0)
- Crystal Structure of PVX_084705 (2014) (0)
- Computationally Designed Symmetric Homotetramer (2017) (0)
- Solution structure of a phosphate-loop protein (2018) (0)
- Crystal Structure of PF3D7_1436600 (2014) (0)
- Crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum - Apo form (2015) (0)
- C3 symmetric peptide design number 1, Sporty, crystal form 1 (2020) (0)
- The Effects of Mutations on Motions of Side-chains in Protein L Studied by 2 H NMR Dynamics and (2003) (0)
- C3_HD-1069 (1BH-69) - fusion protein of helical bundle and repeat protein (2020) (0)
- In silico and in vitro co-evolution of a high affinity complementary protein-protein interface (2011) (0)
- S2 symmetric peptide design number 2, Morticia (2020) (0)
- Structure of a bacterial filament solved by solid-state NMRa: The type III secretion system needle. (2013) (0)
- Crystal structure of rescued two-component self-assembling tetrahedral cage T33-31 (2015) (0)
- Crystal structure of designed two-component self-assembling icosahedral cage I52-32 (2016) (0)
- Crystal Structure of a De Novo Designed Ferredoxin Fold, Northeast Structural Genomics Consortium (NESG) Target OR461 (2014) (0)
- Crystal structure of a de novo designed protein homodimer with curved beta-sheet (2017) (0)
- Crystal Structure of engineered Kumamolisin-As from Alicyclobacillus sendaiensis, Northeast Structural Genomics Consortium (NESG) Target OR367 (2013) (0)
- Hyperstable de novo TIM barrel variant DeNovoTIM15 (2020) (0)
- Chemical shift assignments and structure of the alpha-crystallin domain from human, HSPB5 (2015) (0)
- Towards the de novo design of metallohydrolases (2019) (0)
- Solution NMR Structure of DE NOVO DESIGNED PROTEIN Top7NNSTYCC, Northeast Structural Genomics Consortium (NESG) Target OR34 (2015) (0)
- Designed protein KE59 R1 7/10H with G130S mutation (2012) (0)
- Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414 (2014) (0)
- Crystal structure of computationally designed protein 3DS18 in complex with the human Transferrin receptor ectodomain (2021) (0)
- 1H1648 P22 Computational De Novo Design of Protein Structures(Protein: Property 2,The 49th Annual Meeting of the Biophysical Society of Japan) (2011) (0)
- Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T33-28 (2014) (0)
- Crystal structure of a de novo designed protein with curved beta-sheet (2017) (0)
- DE NOVO DESIGNED HEMAGGLUTININ BINDING PROTEINS (2018) (0)
- Solution NMR structure of De novo designed PLOOP2X3_50 fold protein, Northeast Structural Genomics Consortium (NESG) target OR258 (2016) (0)
- Solution NMR Structure de novo designed rossmann 2x2 fold protein, Northeast Structural Genomics Consortium (NESG) Target OR16 (2009) (0)
- Solution NMR Structure of De novo designed Top7 Fold Protein Top7m13, Northeast Structural Genomics Consortium (NESG) Target OR33 (2013) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR366. (2015) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR264. (2012) (0)
- Crystal structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1, covalently bound with diisopropyl fluorophosphate (DFP), Northeast Structural Genomics Consortium (NESG) Target OR273 (2013) (0)
- Solution structure of the de novo mini protein gHEEE_02 (2016) (0)
- Computationally Designed Cyclic Tetramer ank1C4_7 (2017) (0)
- Three-dimensional structure of the de novo designed serine hydrolase 2bfq_3, Northeast Structural Genomics Consortium (NESG) Target OR248 (2012) (0)
- Crystal Structure of the evolved variant of the computationally designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR275 (2013) (0)
- De novo designed homo-trimeric amantadine-binding protein (2019) (0)
- De novo design of a four-fold symmetric tIM-barrel protein with atomic-level accuracy po-ssu (0)
- Solution NMR Structure of De novo designed FR55, Northeast Structural Genomics Consortium (NESG) Target OR109 (2014) (0)
- Solution NMR structure of de novo designed TMB2.3 (2021) (0)
- Crystal Structure of engineered protein at the resolution 1.98A, Northeast Structural Genomics Consortium Target OR128 (2011) (0)
- Designed two-ring homotetramer at 3.8A resolution (2016) (0)
- Crystal Structure of an engineered protein with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR276 (2014) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63. (2011) (0)
- Crystal structure of designed two-component self-assembling icosahedral cage I53-40 (2016) (0)
- Computationally Designed Self-assembling tetrahedron protein, T308, Crystallized in space group F23 (2012) (0)
- Solution NMR Structure of DE NOVO DESIGNED PROTEIN, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446 (2015) (0)
- Solution NMR Structure of DE NOVO DESIGNED Ferredoxin Fold PROTEIN sfr3, Northeast Structural Genomics Consortium (NESG) Target OR358 (2015) (0)
- Crystal Structure of PVX_084705 in presence of Compound 2 (2015) (0)
- Crystal structure of leukemia inhibitory factor in complex with gp130 (2003) (0)
- Hybrid structure of the Shigella flexneri MxiH Type three secretion system needle (2014) (0)
- NMR ensemble of computationally designed protein XAA (2020) (0)
- 1P089 Theoretical design of functionalized proteins with ideal scaffold(01F. Protein:Engineering,Poster) (2013) (0)
- Design strategy for creating catalytically active metal binding proteins (2019) (0)
- Crystal structure of the formolase FLS_v2 in space group P 21 (2015) (0)
- Computationally Designed Self-assembling Octahedral Cage protein, O333, Crystallized in space group R32 (2012) (0)
- Designed protein KE59 R13 3/11H with benzotriazole (2012) (0)
- Co-LOCKR: de novo designed protein switch (2020) (0)
- Computationally Designed Trimer 1na0C3_3 (2017) (0)
- De novo design of a non-local β-sheet protein with high stability and accuracy (2018) (0)
- Crystal structure of monomeric M-PMV retroviral protease (2011) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR258. (2013) (0)
- Histone deacetylases complex with peptide macrocycles (2021) (0)
- C3 symmetric peptide design number 3 (2020) (0)
- S2 symmetric peptide design number 5, Uncle Fester (2020) (0)
- Solution NMR structure of a de novo designed double-stranded beta-helix (2018) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR266. (2012) (0)
- SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, P-LOOP NTPASE FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR136 (2011) (0)
- Computationally designed C3-symmetric homotrimer from TPR repeat protein (2020) (0)
- NMR ensemble of computationally designed protein XAA_GVDQ mutant M4L (2020) (0)
- Computationally designed protein activation (2019) (0)
- C2 symmetric peptide design number 1, Zappy, crystal form 1 (2020) (0)
- Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR120 (2012) (0)
- Solution NMR Structure of De novo designed protein, Northeast Structural Genomics Consortium (NESG) Target OR462 (2014) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR70 (2011) (0)
- Computationally Designed Two-Component Self-Assembling Tetrahedral Cage T33-15 (2014) (0)
- Designed protein DHD1:234_A, Designed protein DHD1:234_B (2018) (0)
- Crystal structure of Top7: A computationally designed protein with a novel fold (2003) (0)
- Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422 (2013) (0)
- S2 symmetric peptide design number 4 crystal form 1, Pugsley (2020) (0)
- Crystal structure of the designed protein DNCR2/danoprevir/NS3a complex (2019) (0)
- NMR structure of the FF domain L24A mutant's folding transition state (2011) (0)
- Directed evolution and rational design of a de novo designed esterase toward improved catalysis. Northeast Structural Genomics Consortium (NESG) Target OR184 (2013) (0)
- THREE DIMENSIONAL STRUCTURE OF DE NOVO DESIGNED CYSTEINE ESTERASE ECH19, Northeast Structural Genomics Consortium Target OR49 (2011) (0)
- Terbium(III)-bound de novo TIM barrel-ferredoxin fold fusion dimer with 4-glutamate binding site and tryptophan antenna (TFD-EE N6W) (2020) (0)
- 1P088 Principles for designing ideal protein structures(01F. Protein:Engineering,Poster) (2013) (0)
- Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. (2016) (0)
- F86A mutant of E9 DNase domain in complex with Im9 (2008) (0)
- De novo TIM barrel-ferredoxin fold fusion homodimer with 2-histidine 2-glutamate centre TFD-HE (2020) (0)
- Computationally Designed Cyclic Dimer ank3C2_1 (2017) (0)
- Computationally Designed Two-Component Self-Assembling Tetrahedral Cage, T33-21, Crystallized in Space Group F4132 (2014) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR48 (2011) (0)
- S2 symmetric peptide design number 6, London Bridge (2020) (0)
- Crystal Structure of the Sixth BRCT Domain of TopBP1 (2010) (0)
- NMR structure of beta alpha alpha 38 (2014) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR69. (2011) (0)
- X-ray Structure of De Novo design cysteine esterase FR29, Northeast Structural Genomics Consortium Target OR52 (2011) (0)
- Crystal Structure of E6A/L130D/A155H variant of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR186 (2012) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR267. (2012) (0)
- Publisher Correction: Modular and tunable biological feedback control using a de novo protein switch (2020) (0)
- CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900 (2020) (0)
- Solution NMR Structure of DE NOVO DESIGNED PROTEIN, PFK fold, Northeast Structural Genomics Consortium Target OR134 (2012) (0)
- Crystal Structure of the E7_G/Im7_G complex; a designed interface between the colicin E7 DNAse and the Im7 immunity protein (2006) (0)
- S2 symmetric peptide design number 1, Wednesday (2020) (0)
- Crystal structure of the E7_C/Im7_C complex; a computationally designed interface between the colicin E7 DNase and the Im7 Immunity protein (2004) (0)
- NMR solution structure of ALG13 --- obtained with iterative CS-Rosetta from backbone NMR data. (2011) (0)
- Solution NMR Structure of DE NOVO DESIGNED PROTEIN, IF3-like fold, Northeast Structural Genomics Consortium Target OR135 (CASD target) (2012) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR280. (2012) (0)
- Cage photolysis initiates protein folding under native conditions (1999) (0)
- De novo designed protein Foldit1 (2019) (0)
- Backbone 1H, 13C, and 15N Chemical Shift Assignments for gHEEE_02 in presence of 10 mM TCEP (2018) (0)
- Solution structure of the de novo mini protein gEHE_06 (2016) (0)
- Crystal structure of cyclophilin D in complex with CsA analogue, JW47. (2015) (0)
- Solution NMR Structure of de novo designed ferredoxin-like fold protein, Northeast Structural Genomics Consortium Target OR15 (2009) (0)
- Solution NMR structure of the de novo mini protein HEEH_rd4_0097 (2017) (0)
- Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301 (2013) (0)
- Designing de novo retroaldolase catalysts (2019) (0)
- Solution NMR Structure of Maltose-binding protein from Escherichia coli, Northeast Structural Genomics Consortium (NESG) Target ER690 (2014) (0)
- Crystal Structure of the apo form of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1. Northeast Structural Genomics Consortium (NESG) Target OR273 (2013) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR62. (2011) (0)
- 3P098 Computational de novo design of "ideal" protein structures(Protein: Engineering,The 48th Annual Meeting of the Biophysical Society of Japan) (2010) (0)
- Crystal Structure of a gE-gI/Fc complex (2006) (0)
- Crystal Structure of de novo designed serine hydrolase OSH55.14_E3, Northeast Structural Genomics Consortium Target OR342 (2012) (0)
- The crystal structure of Im2 in complex with colicin E9 DNase (2010) (0)
- Crystal Structure of De Novo designed cysteine esterase ECH14, Northeast Structural Genomics Consortium Target OR54 (2011) (0)
- Solution structure of the de novo mini protein EHEE_rd1_0284 (2017) (0)
- S2 symmetric peptide design number 3 crystal form 1, Lurch (2020) (0)
- De novo designed protein Foldit4 (2020) (0)
- Crystal Structure of PVX_084705 bound to compound (2017) (0)
- Crystal Structure of E6H variant of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium (NESG) Target OR185 (2012) (0)
- Chemical shifts for the de novo mini protein gHH_44 in the reduced state. (2018) (0)
- C2 symmetric peptide design number 1, Zappy, crystal form 2 (2020) (0)
- S4 symmetric peptide design number 1, Tim zinc-bound form (2020) (0)
- 2P-097 De novo computational design of "ideal" protein structure(The 46th Annual Meeting of the Biophysical Society of Japan) (2008) (0)
- S2 symmetric peptide design number 4 crystal form 2, Pugsley (2020) (0)
- Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR288 (2013) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR464. (2014) (0)
- Crystal Structure of an engineered protein with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR277 (2014) (0)
- Solution structure of the Aha1 dimer from Colwellia psychrerythraea (2013) (0)
- Solution NMR Structure of denovo designed ferrodoxin fold like protein, Northeast Structural Genomics Consortium Target Target OR15 (2009) (0)
- Crystal Structure of the evolved variant of the computationally designed serine hydrolase, OSH55.4_H1 covalently bound with FP-alkyne, Northeast Structural Genomics Consortium (NESG) Target OR273 (2013) (0)
- C3 symmetric peptide design number 1, Sporty, crystal form 2 (2020) (0)
- Crystal Structure of E6D/L155R variant of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium (NESG) Target OR187 (2012) (0)
- Designed protein KE59 R13 3/11H (2012) (0)
- Crystal Structure of the C-terminal domain of the HSV-1 gE ectodomain (2006) (0)
- De novo Designed Protein Foldit3 (2019) (0)
- De Novo Design of a Protein Heterodimer with Specificity Mediated by Hydrogen Bond Networks (2018) (0)
- Solution Structure of Cold Shock Protein CspA Using Combined NMR and CS-Rosetta method (2010) (0)
- PNAS Plus Significance Statements (2015) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR265. (2012) (0)
- Crystal structure of a de novo designed hexameric helical-bundle protein (2020) (0)
- Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303 (2015) (0)
- de novo Design of Ion Conducting Transmembrane Protein Nanopores (2020) (0)
- Crystal structure of a de novo designed switch protein caging a hemagglutinin binder (2020) (0)
- Crystal structure of pRO-2.3 (2019) (0)
- Crystal structure of engineered protein. northeast structural genomics Consortium target or117 (2013) (0)
- Solution structure of the de novo mini protein EEHEE_rd3_1049 (2017) (0)
- Crystal structure of a putative, de novo designed unnatural amino acid dependent metalloprotein, northeast structural genomics consortium target OR61 (2013) (0)
- Designed protein KE59 R5_11/5F (2012) (0)
- S2 symmetric peptide design number 3 crystal form 2, Lurch (2020) (0)
- Crystal structure of designed two-component self-assembling icosahedral cage I32-28 (2016) (0)
- Crystal Structure of the free human NKG2D immunoreceptor (2003) (0)
- Computationally Designed Self-assembling tetrahedron protein, T310 (2012) (0)
- Solution NMR Structure DE NOVO DESIGNED PFK fold PROTEIN, Northeast Structural Genomics Consortium (NESG) Target OR250 (2012) (0)
- Solution structure of de novo macrocycle design12_ss (2017) (0)
- Three-dimensional structure of triclinic form of de novo design insertion domain, Northeast Structural Genomics Consortium (NESG) Target OR327 (2013) (0)
- Solution NMR Structure of Denovo Beta Sheet Design Protein, Northeast Structural Genomics Consortium (NESG) Target OR664 (2016) (0)
- Catalytic Improvement of an Artificial Metalloenzyme by Computational Design (2015) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR497. (2014) (0)
- A Structural Biology and Protein Engineering Approach to the Engineering Highly Proficient Catalytic Bioscavengers for In Vivo Detoxification of a Broad Spectrum of Nerve Agents (2016) (0)
- Self-assembly of protein-made structures (2019) (0)
- SOLUTION NMR STRUCTURE OF DE NOVO DESIGNED PROTEIN, ROSSMANN 3x1 FOLD, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR157 (2012) (0)
- S4 symmetric peptide design number 1, Tim apo form (2020) (0)
- Crystal Structure of the computationally designed serine hydrolase 3mmj_2, Northeast Structural Genomics Consortium (NESG) Target OR318 (2013) (0)
- Three-dimensional Structure of the orthorhombic crystal of computationally designed insertion domain , Northeast Structural Genomics Consortium (NESG) Target OR327 (2013) (0)
- Solution NMR Structure of De novo designed Protein, Northeast Structural Genomics Consortium (NESG) Target OR457 (2014) (0)
- Prediction and design of protein structures and interactions (2007) (0)
- Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability. (2004) (0)
- C3 symmetric peptide design number 2, Baby Basil (2020) (0)
- De novo designed protein Peak6 (2019) (0)
- Prediction and design of protein folding dynamics (2001) (0)
- 1SB-01 Computational De Novo Design of Protein Structures(1SB Exploring design principles of life,The 49th Annual Meeting of the Biophysical Society of Japan) (2011) (0)
- 13C and 15N chemical shifts for Shigella Flexneri MxiH Type three secretion system needle subunit (2013) (0)
- Structure of URNdesign, a complete computational redesign of human U1A protein (2006) (0)
- Crystal Structure of HTC1 (2016) (0)
- Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR465 (2014) (0)
- De novo TIM barrel-ferredoxin fold fusion homodimer with 4-glutamate centre TFD-EE (2020) (0)
- Crystal Structure of a De Novo Designed Beta Sheet Protein, Cystatin Fold, Northeast Structural Genomics Consortium (NESG) Target OR486 (2014) (0)
- De novo designed protein Ferredog-Diesel (2019) (0)
- NMR structure of a strand-swapped dimer of the WW domain (2014) (0)
- X-ray diffraction data for the dHD15_closed (6DMA) (2018) (0)
- Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR329 (2012) (0)
- Models for 58 protein families predicted with Rosetta-GREMLIN (2015) (0)
- Reporting@Home: Delivering Dynamic Graphical Feedback to Participants and Researchers in Community Computing Projects (2007) (0)
- Erratum: Conversion of monomeric protein L to an obligate dimer by computational protein design (Proceedings of the National Academy of Sciences of the United States of America (September 11, 2001) 98:19 (10687-10691)) (2002) (0)
- Increasing computational protein design literacy through cohort-based learning for undergraduate students (2022) (0)
- Structure Prediction using Coevolution (2015) (0)
- 3-D Enzymatic Nanomaterial Architectures for Energy Harvesting (2016) (0)
- Monomeric Protein L B1 Domain with a G15A Mutation (2001) (0)
- An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12 (2018) (0)
- De novo design of small beta barrel proteins (2023) (0)
- Accurate Mutation Effect Prediction using RoseTTAFold (2022) (0)
- A G55A Mutation Induces 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus (2001) (0)
- Combining Crystallographic and Structure-Modeling Approaches in Macromolecular Crystallography (2014) (0)
- Crystal structure of beta sheet heterodimer LHD29 (2021) (0)
- Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions (2023) (0)
- Genetic manipulation of candidate phyla radiation bacteria provides functional insights into microbial dark matter (2023) (0)
- Elucidating bacterial lipid transport mechanisms by the envelope-spanning LetAB complex. (2022) (0)
- Hallucination of closed repeat proteins containing central pockets (2022) (0)
- phenix.mr_rosetta: a new tool for difficult molecular replacement problems (2011) (0)
- Molecular Traffic Jams on DNA (2018) (0)
- The Origin of Consistent P rotein Structure Refinement from Structural Averaging Graphical Abstract Highlights (0)
- Crystal Structure of Actin-like protein Alp7A (2016) (0)
- Programmable design of orthogonal protein heterodimers (2018) (0)
- De Novo model of Bacteriophage P22 virion coat protein (2011) (0)
- Thermodynamic hyperstability in parametrically designed helical bundles (2014) (0)
- Extending the limits in solving and rebuilding molecular replacement structures (2011) (0)
- Lidless D386A Mm-cpn in the pre-hydrolysis ATP-bound state (2011) (0)
- Structure Technical Advance High-ResolutionComparativeModelingwithRosettaCM (2013) (0)
- Independent reconstruction of Mm-cpn cryo-EM density map from half dataset in the closed state (training map) (2013) (0)
- De Novo model of Bacteriophage P22 procapsid coat protein (2011) (0)
- Computationally designed three helix bundle (2014) (0)
- De novo protein design by citizen scientists (2019) (0)
- Atomic model of the VipA/VipB, the type six secretion system contractile sheath of Vibrio cholerae from cryo-EM (2015) (0)
- Model-building with PHENIX and Rosetta (2011) (0)
- Author response for "Perturbing the energy landscape for improved packing during computational protein design" (2020) (0)
- De novo design of proteins with two isoenergetic but structurally divergent ground states (2019) (0)
- Supplemental Information High-Resolution Comparative Modeling with RosettaCM (2013) (0)
- Advances, Interactions, and Future Developments in the CNS, Phenix, and Rosetta Structural Biology Software Systems Annual Review of Biophysics (2012) (0)
- Computational design of transmembrane pores (2020) (0)
- Crystal structure of transmembrane protein TMHC2_E (2018) (0)
- Lidless Mm-cpn in the closed state with ATP/AlFx (2011) (0)
- Crystal structure of De novo designed ferredoxin-ferredoxin domain insertion protein (2015) (0)
- Varying the Directionality of Protein Catalysts for Aldol and Retro‐Aldol Reactions (2021) (0)
- Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies (2023) (0)
- Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6. (2023) (0)
- Exploiting conformational dynamics to modulate the function of designed proteins. (2023) (0)
- Design of stimulus-responsive two-state hinge proteins (2023) (0)
- Design and optimization of enzymatic activity in a de novo β‐barrel scaffold (2022) (0)
- Design of amyloidogenic peptide traps (2023) (0)
- Precisely patterned nanofibers made from extendable protein multiplexes (2022) (0)
- Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks (2022) (0)
- Designed sensors reveal normal and oncogenic Ras signaling in endomembranes and condensates (2022) (0)
- Computational design of non-porous, pH-responsive antibody nanoparticles (2023) (0)
- Top-down design of protein architectures with reinforcement learning (2023) (0)
- Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers (2023) (0)
- Stepwise design of pseudosymmetric protein hetero-oligomers (2023) (0)
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