David Borsook
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David Borsook's Degrees
- Doctorate Medicine Harvard University
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(Suggest an Edit or Addition)David Borsook's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Migraine: Multiple Processes, Complex Pathophysiology (2015) (505)
- Reward Circuitry Activation by Noxious Thermal Stimuli (2001) (488)
- Human brain activation under controlled thermal stimulation and habituation to noxious heat: An fMRI study (1999) (334)
- Neural circuitry underlying pain modulation: expectation, hypnosis, placebo (2003) (332)
- Alterations in brain structure and functional connectivity in prescription opioid-dependent patients. (2010) (327)
- Thalamic sensitization transforms localized pain into widespread allodynia (2010) (308)
- Neuroimaging of the periaqueductal gray: State of the field (2012) (308)
- Psychological processing in chronic pain: A neural systems approach (2014) (294)
- Understanding Migraine through the Lens of Maladaptive Stress Responses: A Model Disease of Allostatic Load (2012) (270)
- A key role of the basal ganglia in pain and analgesia - insights gained through human functional imaging (2010) (258)
- The cerebellum and pain: Passive integrator or active participator? (2010) (255)
- Preclinical Assessment of Candidate Analgesic Drugs: Recent Advances and Future Challenges (2006) (246)
- Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial (2015) (238)
- Acute plasticity in the human somatosensory cortex following amputation (1998) (225)
- Common Brain Mechanisms of Chronic Pain and Addiction (2016) (215)
- Somatotopic Activation in the Human Trigeminal Pain Pathway (2002) (204)
- Neurological diseases and pain. (2012) (203)
- Interictal Dysfunction of a Brainstem Descending Modulatory Center in Migraine Patients (2008) (201)
- Painful heat reveals hyperexcitability of the temporal pole in interictal and ictal migraine States. (2011) (198)
- A role for fMRI in optimizing CNS drug development (2006) (191)
- The human amygdala and pain: Evidence from neuroimaging (2014) (190)
- Trigeminal Neuropathic Pain Alters Responses in CNS Circuits to Mechanical (Brush) and Thermal (Cold and Heat) Stimuli (2006) (183)
- The corneal pain system. Part I: the missing piece of the dry eye puzzle. (2012) (174)
- fMRI reveals distinct CNS processing during symptomatic and recovered complex regional pain syndrome in children. (2008) (173)
- Aversion-Related Circuitry in the Cerebellum: Responses to Noxious Heat and Unpleasant Images (2011) (170)
- Her versus his migraine: multiple sex differences in brain function and structure. (2012) (169)
- Pain and suicidality: Insights from reward and addiction neuroscience (2013) (168)
- Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study (2000) (168)
- Concurrent functional and structural cortical alterations in migraine (2012) (165)
- Pain and analgesia: The value of salience circuits (2013) (162)
- Cortical Projections of Functionally Identified Thalamic Trigeminovascular Neurons: Implications for Migraine Headache and Its Associated Symptoms (2011) (149)
- Reward deficiency and anti-reward in pain chronification (2016) (149)
- Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities (2020) (146)
- Ocular neuropathic pain (2015) (144)
- Migraine attacks the Basal Ganglia (2011) (141)
- The cerebellum and addiction: insights gained from neuroimaging research (2014) (137)
- Functional Magnetic Resonance Imaging Measures of the Effects of Morphine on Central Nervous System Circuitry in Opioid-Naive Healthy Volunteers (2006) (137)
- Food Intake and Reward Mechanisms in Patients with Schizophrenia: Implications for Metabolic Disturbances and Treatment with Second-Generation Antipsychotic Agents (2006) (136)
- The opioid contract in the management of chronic pain. (1999) (135)
- Common hippocampal structural and functional changes in migraine (2013) (131)
- The young brain and concussion: Imaging as a biomarker for diagnosis and prognosis (2012) (127)
- Reward‐aversion circuitry in analgesia and pain: Implications for psychiatric disorders (2007) (127)
- Colocalized Structural and Functional Changes in the Cortex of Patients with Trigeminal Neuropathic Pain (2008) (125)
- Signal valence in the nucleus accumbens to pain onset and offset (2008) (123)
- When pain gets stuck: the evolution of pain chronification and treatment resistance (2018) (120)
- Surgically Induced Neuropathic Pain: Understanding the Perioperative Process (2013) (119)
- Robust Reproducible Resting State Networks in the Awake Rodent Brain (2011) (114)
- Altered Hypothalamic Functional Connectivity with Autonomic Circuits and the Locus Coeruleus in Migraine (2014) (113)
- The missing p in psychiatric training: why it is important to teach pain to psychiatrists. (2011) (112)
- fMRI measurement of CNS responses to naloxone infusion and subsequent mild noxious thermal stimuli in healthy volunteers. (2004) (109)
- The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations. (2017) (108)
- Migraine photophobia originating in cone-driven retinal pathways. (2016) (108)
- Adherence monitoring and drug surveillance in chronic opioid therapy. (2000) (108)
- Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. (2013) (106)
- Specificity of Hemodynamic Brain Responses to Painful Stimuli: A functional near-infrared spectroscopy study (2015) (105)
- Biomarkers for chronic pain and analgesia. Part 1: the need, reality, challenges, and solutions. (2011) (102)
- The Insula (2016) (101)
- Migraine changes the brain: neuroimaging makes its mark. (2012) (100)
- Mayer waves reduce the accuracy of estimated hemodynamic response functions in functional near-infrared spectroscopy. (2016) (97)
- Autologous Serum Tears for Treatment of Photoallodynia in Patients with Corneal Neuropathy: Efficacy and Evaluation with In Vivo Confocal Microscopy. (2015) (97)
- Breaking down the barriers: fMRI applications in pain, analgesia and analgesics (2006) (97)
- Fos-like immunoreactivity in the superficial medullary dorsal horn induced by noxious and innocuous thermal stimulation of facial skin in the rat. (1993) (96)
- Functional imaging of the human trigeminal system: opportunities for new insights into pain processing in health and disease. (2004) (95)
- Unmasking the mysteries of the habenula in pain and analgesia (2012) (94)
- The responsive amygdala: Treatment-induced alterations in functional connectivity in pediatric complex regional pain syndrome (2014) (92)
- Lost but making progress—Where will new analgesic drugs come from? (2014) (91)
- Mapping pain activation and connectivity of the human habenula. (2012) (87)
- Intravenous methadone for cancer pain unrelieved by morphine and hydromorphone: clinical observations (1997) (86)
- Excitatory neurotransmitters in brain regions in interictal migraine patients (2009) (86)
- An fMRI case report of photophobia: Activation of the trigeminal nociceptive pathway (2009) (86)
- Rapid treatment-induced brain changes in pediatric CRPS (2016) (84)
- Analogous responses in the nucleus accumbens and cingulate cortex to pain onset (aversion) and offset (relief) in rats and humans. (2013) (84)
- Migraine: Maladaptive Brain Responses to Stress (2012) (82)
- Neuroimaging revolutionizes therapeutic approaches to chronic pain (2007) (82)
- Specific and Somatotopic Functional Magnetic Resonance Imaging Activation in the Trigeminal Ganglion by Brush and Noxious Heat (2003) (80)
- BOLD Responses in Somatosensory Cortices Better Reflect Heat Sensation than Pain (2012) (80)
- The Pain Imaging Revolution: Advancing Pain Into the 21st Century (2010) (80)
- Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress. (1994) (79)
- Short separation regression improves statistical significance and better localizes the hemodynamic response obtained by near-infrared spectroscopy for tasks with differing autonomic responses (2015) (77)
- Human cerebellar responses to brush and heat stimuli in healthy and neuropathic pain subjects (2008) (76)
- Neurochemical Pathways That Converge on Thalamic Trigeminovascular Neurons: Potential Substrate for Modulation of Migraine by Sleep, Food Intake, Stress and Anxiety (2014) (76)
- Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome (2014) (75)
- Sex and the migraine brain (2014) (75)
- Role of brain imaging in disorders of brain–gut interaction: a Rome Working Team Report (2019) (72)
- Increased Amplitude of Thalamocortical Low-Frequency Oscillations in Patients with Migraine (2016) (70)
- Diffuse optical tomography of pain and tactile stimulation: Activation in cortical sensory and emotional systems (2008) (69)
- Injection of the Piriformis Muscle by Fluoroscopic and Electromyographic Guidance (1998) (68)
- Brodmann area 10: Collating, integrating and high level processing of nociception and pain (2017) (67)
- Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: A potential biomarker of efficacy (2014) (67)
- Biomarkers for chronic pain and analgesia. Part 2: how, where, and what to look for using functional imaging. (2011) (65)
- Nitroglycerin as a comparative experimental model of migraine pain: From animal to human and back (2019) (63)
- Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: Implications for photophobia (2012) (62)
- Imaging Drugs with and without Clinical Analgesic Efficacy (2011) (62)
- CNS animal fMRI in pain and analgesia (2011) (61)
- The enigma of the dorsolateral pons as a migraine generator (2012) (61)
- Capsaicin-induced thermal hyperalgesia and sensitization in the human trigeminal nociceptive pathway: An fMRI study (2007) (58)
- Molecular neurobiology of pain (1997) (56)
- Psychosocial stress and its relationship to gambling urges in individuals with pathological gambling. (2010) (56)
- Distraction Analgesia in Chronic Pain Patients: The Impact of Catastrophizing (2014) (55)
- Children With Chronic Pain: Response Trajectories After Intensive Pain Rehabilitation Treatment. (2017) (53)
- Segmentally arranged somatotopy within the face representation of human primary somatosensory cortex (2009) (52)
- Activation of pial and dural macrophages and dendritic cells by cortical spreading depression (2018) (51)
- Habenula functional resting-state connectivity in pediatric CRPS. (2014) (50)
- Pediatric Pain Screening Tool: rapid identification of risk in youth with pain complaints (2015) (50)
- Functional Imaging of the Trigeminal System: Applications to Migraine Pathophysiology (2006) (49)
- Diffuse Optical Tomography Activation in the Somatosensory Cortex: Specific Activation by Painful vs. Non-Painful Thermal Stimuli (2009) (49)
- Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine (2012) (49)
- Noninvasive mapping of human trigeminal brainstem pathways (2008) (48)
- Anesthesia and perioperative stress: Consequences on neural networks and postoperative behaviors (2010) (48)
- Retrospective accounts of initial subjective effects of opioids in patients treated for pain who do or do not develop opioid addiction: a pilot case-control study. (2008) (47)
- Harnessing the placebo effect in pediatric migraine clinic. (2014) (47)
- Transient and Persistent Pain Induced Connectivity Alterations in Pediatric Complex Regional Pain Syndrome (2013) (47)
- CNS activation maps in awake rats exposed to thermal stimuli to the dorsum of the hindpaw (2011) (46)
- Neuropeptides and Neurotransmitters That Modulate Thalamo‐Cortical Pathways Relevant to Migraine Headache (2017) (46)
- The migraine brain in transition: girls vs boys (2015) (45)
- Can functional magnetic resonance imaging improve success rates in central nervous system drug discovery? (2011) (45)
- Use of functional imaging across clinical phases in CNS drug development (2013) (45)
- Increased Functional Activation of Limbic Brain Regions during Negative Emotional Processing in Migraine (2016) (45)
- Abdominal Pain, the Adolescent and Altered Brain Structure and Function (2016) (45)
- Distinct lateral and medial projections of the spinohypothalamic tract of the rat (1996) (44)
- Brain changes after spinal cord injury, a quantitative meta-analysis and review (2018) (43)
- Threat Response System: Parallel Brain Processes in Pain vis-à-vis Fear and Anxiety (2018) (43)
- Brain Changes in Responders vs. Non-Responders in Chronic Migraine: Markers of Disease Reversal (2016) (43)
- An Approach to Localizing Corneal Pain Representation in Human Primary Somatosensory Cortex (2012) (43)
- Neural mechanism for hypothalamic-mediated autonomic responses to light during migraine (2017) (43)
- Enhanced false discovery rate using Gaussian mixture models for thresholding fMRI statistical maps (2009) (43)
- CNS Measures of Pain Responses Pre- and Post-Anesthetic Ketamine in a Patient with Complex Regional Pain Syndrome. (2009) (42)
- Losses and gains: chronic pain and altered brain morphology (2013) (42)
- Anesthesia, brain changes, and behavior: Insights from neural systems biology (2017) (41)
- Inflaming the Brain: CRPS a Model Disease to Understand Neuroimmune Interactions in Chronic Pain (2013) (41)
- Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain. (2012) (41)
- Female migraineurs show lack of insular thinning with age (2015) (38)
- Cortico–Cortical Connections of Primary Sensory Areas and Associated Symptoms in Migraine (2016) (38)
- The role of imaging (2014) (38)
- Parallel Buprenorphine phMRI Responses in Conscious Rodents and Healthy Human Subjects (2013) (37)
- Primary Somatosensory Cortices Contain Altered Patterns of Regional Cerebral Blood Flow in the Interictal Phase of Migraine (2015) (37)
- Identifying Rodent Resting-State Brain Networks with Independent Component Analysis (2017) (35)
- Frontal Lobe Hemodynamic Responses to Painful Stimulation: A Potential Brain Marker of Nociception (2016) (35)
- Migrainomics — identifying brain and genetic markers of migraine (2017) (35)
- Behavioral and pharmacological characterization of a distal peripheral nerve injury in the rat (2005) (33)
- Secondary effects on brain physiology caused by focused ultrasound-mediated disruption of the blood-brain barrier. (2020) (33)
- Chronic (neuropathic) corneal pain and blepharospasm: Five case reports (2011) (33)
- Comparison of evoked vs. spontaneous tics in a patient with trigeminal neuralgia (tic doloureux) (2007) (33)
- Resting-State Functional Connectivity in the Infant Brain: Methods, Pitfalls, and Potentiality (2017) (32)
- Capturing Pain in the Cortex during General Anesthesia: Near Infrared Spectroscopy Measures in Patients Undergoing Catheter Ablation of Arrhythmias (2016) (32)
- Oculofacial Pain: Corneal Nerve Damage Leading to Pain Beyond the Eye (2016) (32)
- Brain network alterations in the inflammatory soup animal model of migraine (2017) (31)
- Cyclic AMP‐Dependent Activation of the Proenkephalin Gene Requires Phosphorylation of CREB at Serine‐133 and a Src‐Related Kinase (1999) (30)
- A ‘BOLD’ experiment in defining the utility of fMRI in drug development (2008) (30)
- Proenkephalin gene regulation in the neuroendocrine hypothalamus: a model of gene regulation in the CNS. (1995) (30)
- Responsivity of Periaqueductal Gray Connectivity Is Related to Headache Frequency in Episodic Migraine (2018) (30)
- Utilizing brain imaging for analgesic drug development. (2002) (29)
- Reward and aversion processing in patients with post-traumatic stress disorder: functional neuroimaging with visual and thermal stimuli (2018) (29)
- The effect of naltrexone on body fat mass in olanzapine-treated schizophrenic or schizoaffective patients: A randomized double-blind placebo-controlled pilot study (2014) (29)
- Calcitonin Gene-Related Peptide Modulates Heat Nociception in the Human Brain - An fMRI Study in Healthy Volunteers (2016) (28)
- Transforming pain medicine: Adapting to science and society (2013) (28)
- Basal ganglia dysfunction in complex regional pain syndrome – A valid hypothesis? (2017) (28)
- Parental Attitudes About Placebo Use in Children (2017) (28)
- Endometriosis and pain in the adolescent- striking early to limit suffering: A narrative review (2019) (28)
- A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements. (2011) (28)
- A ‘complex’ of brain metabolites distinguish altered chemistry in the cingulate cortex of episodic migraine patients (2016) (28)
- A Future Without Chronic Pain: Neuroscience and Clinical Research (2012) (27)
- Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy (2016) (27)
- A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices. (2011) (27)
- Yohimbine-Induced Amygdala Activation in Pathological Gamblers: A Pilot Study (2012) (27)
- Fear and Reward Circuit Alterations in Pediatric CRPS (2016) (26)
- Expression and regulation of a proenkephalin beta-galactosidase fusion gene in the reproductive system of transgenic mice. (1992) (26)
- A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study. (2010) (26)
- Pain Facilitation Brain Regions Activated by Nalbuphine Are Revealed by Pharmacological fMRI (2013) (26)
- The failing cascade: Comorbid post traumatic stress- and opioid use disorders (2019) (26)
- Triptans disrupt brain networks and promote stress-induced CSD-like responses in cortical and subcortical areas. (2016) (26)
- Systemic lipopolysaccharide and interleukin-1β activate the interleukin 6: STAT intracellular signaling pathway in neurons of mouse trigeminal ganglion (2000) (25)
- Nocebo Effect in Randomized Clinical Trials of Antidepressants in Children and Adolescents: Systematic Review and Meta-Analysis (2014) (25)
- Insights and Advances in Post-traumatic Headache: Research Considerations (2014) (24)
- Cluster headache: A review of neuroimaging findings (2007) (24)
- Focused ultrasound induced opening of the blood-brain barrier disrupts inter-hemispheric resting state functional connectivity in the rat brain (2018) (24)
- Test–retest reliability of evoked heat stimulation BOLD fMRI (2015) (24)
- Estrogen and Stress Interact to Regulate the Hypothalamic Expression of a Human Proenkephalin Promoter‐β‐Galactosidase Fusion Gene in a Site‐Specific and Sex‐Specific Manner (1997) (24)
- Is There Such Thing as a Schizophrenic Stomach? (2006) (24)
- Pain and motor system plasticity (2007) (23)
- Phenotyping central nervous system circuitry in chronic pain using functional MRI: Considerations and potential implications in the clinic (2007) (23)
- Placebo: From Pain and Analgesia to Preferences and Products (2005) (23)
- Pain response measured with arterial spin labeling (2013) (22)
- Ketamine and chronic pain – Going the distance (2009) (22)
- Improved characterization of BOLD responses for evoked sensory stimuli (2010) (22)
- NIRS measures in pain and analgesia: Fundamentals, features, and function (2020) (21)
- Modulation of brain function by targeted delivery of GABA through the disrupted blood-brain barrier (2019) (21)
- Morphine Attenuates fNIRS Signal Associated With Painful Stimuli in the Medial Frontopolar Cortex (medial BA 10) (2018) (20)
- A critical evaluation of validity and utility of translational imaging in pain and analgesia: Utilizing functional imaging to enhance the process (2018) (20)
- Age- and sex-related differences in the presentation of paediatric migraine: A retrospective cohort study (2018) (20)
- CNS activation by noxious heat to the hand or foot: site-dependent delay in sensory but not emotion circuitry. (2004) (20)
- Stress-induced regulation of a human proenkephalin-beta-galactosidase fusion gene in the hypothalamus of transgenic mice. (1994) (20)
- Daily rhythms of benzodiazepine receptor numbers in frontal lobe and cerebellum of the rat. (1985) (20)
- The migraine eye: distinct rod-driven retinal pathways' response to dim light challenges the visual cortex hyperexcitability theory (2018) (19)
- GABA and circadian timekeeping: implications for manic-depression and sleep disorders. (1986) (19)
- Using prerecorded hemodynamic response functions in detecting prefrontal pain response: a functional near-infrared spectroscopy study (2017) (19)
- Implications of the putamen in pain and motor deficits in complex regional pain syndrome. (2019) (19)
- Molecular and functional PET-fMRI measures of placebo analgesia in episodic migraine: Preliminary findings (2017) (19)
- Circles of engagement: Childhood pain and parent brain (2016) (19)
- Regulation of opioid gene expression: a model to understand neural plasticity. (1992) (19)
- Effects of naltrexone on food intake and body weight gain in olanzapine-treated rats (2012) (18)
- Pain imaging: future applications to integrative clinical and basic neurobiology. (2003) (18)
- Challenges of functional imaging research of pain in children (2009) (18)
- Ictal and interictal brain activation in episodic migraine: Neural basis for extent of allodynia. (2021) (18)
- The febrile responses in rabbits and rats to leucocyte pyrogens of different species. (1978) (18)
- Pain in an era of armed conflicts: Prevention and treatment for warfighters and civilian casualties (2016) (17)
- Probing Intrinsic Resting-State Networks in the Infant Rat Brain (2016) (17)
- The neurovascular response is attenuated by focused ultrasound-mediated disruption of the blood-brain barrier (2019) (17)
- Functional imaging of pain and analgesia—A valid diagnostic tool? (2005) (16)
- Longitudinal Evaluation of Pain, Flare‐Up, and Emotional Health in Fibrodysplasia Ossificans Progressiva: Analyses of the International FOP Registry (2019) (16)
- The Effect of Antinociceptive Drugs Tested at Different Times After Nerve Injury in Rats (2005) (16)
- Color-selective photophobia in ictal vs interictal migraineurs and in healthy controls (2018) (16)
- In child and adult migraineurs the somatosensory cortex stands out … again: An arterial spin labeling investigation (2017) (16)
- A Simple and Objective Method for Reproducible Resting State Network (RSN) Detection in fMRI (2011) (16)
- Emotional Pain without Sensory Pain—Dream On? (2009) (16)
- Intravenous lidocaine for treatment-resistant pruritus. (1997) (15)
- Managing insomnia : an overview of insomnia and pharmacologic treatment strategies in use and on the horizon (15)
- Migraine Tweets – What can online behavior tell us about disease? (2013) (15)
- Metabolic and Addiction Indices in Patients on Opioid Agonist Medication-Assisted Treatment: A Comparison of Buprenorphine and Methadone (2020) (15)
- Pain Detection with fNIRS-Measured Brain Signals: A Personalized Machine Learning Approach Using the Wavelet Transform and Bayesian Hierarchical Modeling with Dirichlet Process Priors (2019) (15)
- Opioidergic tone and pain susceptibility: interactions between reward systems and opioid receptors. (2017) (14)
- Shifting brain circuits in pain chronicity (2019) (14)
- CNS Measures of Pain Responses Pre- and Post-Anesthetic Ketamine in a Patient with Complex Regional Pain Syndrome. (2015) (14)
- CNS response to a thermal stressor in human volunteers and rats may predict the clinical utility of analgesics (2007) (14)
- How Close Are We in Utilizing Functional Neuroimaging in Routine Clinical Diagnosis of Neuropathic Pain? (2011) (14)
- A Single Intravenous Injection of KRN5500 (Antibiotic Spicamycin) Produces Long-Term Decreases in Multiple Sensory Hypersensitivities in Neuropathic Pain (2003) (13)
- A dissociation between temperature regulation and fever in the rabbit. (1977) (13)
- Corticosteroid-induced mania after single regional application at the celiac plexus. (1996) (13)
- Brain signatures of threat-safety discrimination in adolescent chronic pain. (2019) (13)
- Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: a model of endogenous opioid gene regulation by exogenous opioids (1994) (13)
- The Migraine Brain: Imaging Structure and Function (2012) (13)
- Chapter 42 – Migraine (2015) (12)
- Antineuropathic effects of the antibiotic derivative spicamycin KRN5500. (2004) (12)
- Clinical features and sex differences in pediatric post-traumatic headache: A retrospective chart review at a Boston area concussion clinic (2019) (12)
- Subliminal (latent) processing of pain and its evolution to conscious awareness (2018) (11)
- Massachusetts General Hospital tratamiento del dolor (1999) (11)
- Pain: Do ACE inhibitors exacerbate complex regional pain syndrome? (2009) (11)
- The brain and behavioral correlates of motor-related analgesia (MRA) (2020) (10)
- Taking the headache out of migraine. (2015) (10)
- Brain Imaging in Migraine Research (2010) (10)
- The Challenges and Opportunities (2010) (10)
- Robust, unbiased general linear model estimation of phMRI signal amplitude in the presence of variation in the temporal response profile (2010) (10)
- Biological and behavioral markers of pain following nerve injury in humans (2019) (10)
- Microstructural White Matter Abnormalities in the Dorsal Cingulum of Adolescents with IBS (2018) (10)
- The Effects of KRN5500, a Spicamycin Derivative, on Neuropathic and Nociceptive Pain Models in Rats (2000) (10)
- Proenkephalin transgene regulation in the paraventricular nucleus of the hypothalamus by lipopolysaccharide and interleukin‐1β (1999) (10)
- Alterations in the structure and function of the brain in adolescents with new daily persistent headache: A pilot MRI study (2022) (9)
- Opioids modulate stress-induced proenkephalin gene expression in the hypothalamus of transgenic mice: A model of endogenous opioid gene regulation by exogenous opioids (1994) (9)
- Cumulative effects of multiple pain sites in youth with chronic pain (2018) (9)
- Using NMR approaches to drive the search for new CNS therapeutics. (2010) (9)
- A water-soluble synthetic spicamycin derivative (San-Gly) decreases mechanical allodynia in a rodent model of neuropathic pain (2002) (9)
- Migraine in the Young Brain: Adolescents vs. Young Adults (2019) (9)
- Imaging in CNS Drug Discovery and Development (2009) (9)
- Multi-task multiple kernel machines for personalized pain recognition from functional near-infrared spectroscopy brain signals (2018) (8)
- C-Fiber Assays in the Cornea vs. Skin (2019) (8)
- A new electronic diary tool for mapping and tracking spatial and temporal head pain patterns in migraine (2015) (8)
- Beating pain with psychedelics: Matter over mind? (2021) (8)
- Modulation of Resting State Functional Connectivity of the Brain by Naloxone Infusion (2008) (8)
- Neuropathic corneal pain and dry eye: a continuum of nociception (2021) (8)
- Modulation of Brain Networks by Sumatriptan-Naproxen in the Inflammatory-Soup Migraine Model. (2019) (7)
- PhosphoCREB and CREM/ICER (1999) (7)
- Pain and spinal cord imaging measures in children with demyelinating disease (2015) (7)
- Delineating conditions and subtypes in chronic pain using neuroimaging (2019) (7)
- Evaluation of novel drugs using fMRI in early-phase clinical trials: safety monitoring. (2010) (7)
- Pain: the past, present and future. (2003) (6)
- Migraine Mistakes (2014) (6)
- Blue light activates pulvinar nuclei in longstanding idiopathic photophobia: A case report (2019) (6)
- Altered Brain Network Connectivity underlies Persistent Post-Traumatic Headache following mTBI in Youth. (2020) (6)
- Adriamycin injection into the medial cord of the brachial plexus: computed tomography-guided targeted pain therapy. (2008) (6)
- Temperature acclimation and learning in fish (2005) (6)
- Thalamocortical Connectivity in Experimentally-Induced Migraine Attacks: A Pilot Study (2021) (6)
- Targeted manipulation of pain neural networks: The potential of focused ultrasound for treatment of chronic pain (2020) (5)
- Pharmacological approaches to the treatment of chronic pain: New concepts and critical issues. Progress in pain research and management, vol 1. Edited by Howard L. Fields and John C. Liebeskind Seattle, IASP, 1994 312 pp, illustrated, $55.00 (1994) (5)
- Completing the Pain Circuit: Recent Advances in Imaging Pain and Inflammation beyond the Central Nervous System (2013) (5)
- Mechanism-based Classifications of Pain and Analgesic Drug Discovery (2003) (5)
- Scale-Free Amplitude Modulation of Low-Frequency Fluctuations in Episodic Migraine. (2019) (5)
- Amygdala functional connectivity mediates the association between catastrophizing and threat-safety learning in youth with chronic pain. (2021) (5)
- Stressful experiences in youth: “Set-up” for diminished resilience to chronic pain (2020) (5)
- Erratum to “Noxious heat induces fMRI activation in two anatomically distinct clusters within the nucleus accumbens” [Neurosci. Lett. 392 (2006) 159–164] (2006) (4)
- Developing Common Data Elements (CDEs) for headache clinical research: A National Institute of Neurological Disorders and Stroke (NINDS), NIH initiative (2012) (4)
- Mechanisms regulating proenkephalin gene expression: contributions of transgenic models. (1996) (4)
- Targeting the stress response in pediatric pain: current evidence for psychosocial intervention and avenues for future investigation (2021) (4)
- Proenkephalin Gene Regulation in the Paraventricular Nucleus by GABA: Interactions with Opioid Systems in a Transgenic Model (1998) (4)
- Stress, hypoglycemia, and the autonomic nervous system (2022) (3)
- A lateralized model of the pain-depression dyad (2021) (3)
- The effect of evening light on circadian-related outcomes: A systematic review. (2022) (3)
- Opioids and neurotrophic effects (1994) (3)
- Insights into pain mechanisms through functional MRI (2006) (3)
- Pain mechanisms and management in corneal cross-linking: a review (2021) (3)
- Rhythmic Change of Cortical Hemodynamic Signals Associated with Ongoing Nociception in Awake and Anesthetized Individuals: An Exploratory Functional Near Infrared Spectroscopy Study (2021) (3)
- Random Forest Segregation of Drug Responses May Define Regions of Biological Significance (2016) (3)
- Reasons to Believe: The Potential of Imaging in CNS Drug Development (2010) (3)
- Brain resting-state connectivity in the development of secondary hyperalgesia in healthy men (2019) (3)
- A Statistical Framework for Optimal Design Matrix Generation With Application to fMRI (2009) (3)
- Morphological Brain Changes in Chronic Pain (2014) (2)
- Preventing pediatric chronic postsurgical pain: Time for increased rigor (2022) (2)
- Decreased Brain Neurokinin-1 Receptor Availability in Chronic Tennis Elbow (2016) (2)
- Comparison of BOLD Response Modulation During Pain Stimulation and Resting-State Conditions Under Intravenous ( 0 . 2 mg / 70 kg ) or Sublingual ( 2 mg ) Buprenorphine Treatment (2009) (2)
- Objectifying chronic pain: from the patient to diagnostic metrics. (2013) (2)
- fNIRS brain measures of ongoing nociception during surgical incisions under anesthesia (2022) (2)
- Functional MRI of pain: Noxious heat and cold stimuli (1997) (2)
- Children with Chronic Pain: Response Trajectories following Intensive Pain Rehabilitation Treatment (2018) (2)
- Enhancing Choice and Outcomes for Therapeutic Trials in Chronic Pain: N-of-1 + Imaging (+ i). (2020) (2)
- Visuospatial and Sensory Integration Tasks in Patients With Schizophrenia or Schizoaffective Disorder: Relationship to Body Mass Index and Smoking (2018) (2)
- Theoretical basis of pain (2021) (2)
- Brain-based measures of nociception during general anesthesia with remifentanil: A randomized controlled trial (2022) (2)
- Migraine: interactions between brain’s trait and state (2021) (2)
- Functional Brain Imaging of Facial Pain: Functional Magnetic Resonance Imaging (FMRI) Studies of the Trigeminal System (2007) (2)
- Comparison of Cortical Responses to Noxious Contact Heat using fMRI in Interictal Migraine Patients and Matched Healthy Controls. (2009) (2)
- Mechanisms Underlying Unconscious Processing and Their Alterations in Post-traumatic Stress Disorder: Neuroimaging of Zero Monetary Outcomes Contextually Framed as “No Losses” vs. “No Gains” (2020) (2)
- Biological laterality and peripheral nerve DTI metrics (2021) (1)
- 5-Hydroxytryptamine depletion attenuates hypothermia in rats. (1980) (1)
- The role of hippocampus and amygdala morphology in memory bias of learned fear in youth with chronic pain (2021) (1)
- CNS Animal fMRI imaging in Pain and Analgesia (2011) (1)
- Comorbid opioid use disorder and post-traumatic stress disorder. (2022) (1)
- ADIS - A robust pursuit algorithm for probabilistic, constrained and non-square blind source separation with application to fMRI (2009) (1)
- ‘Hot Feet – Hot Brain’: Gene and brain dysfunction in erythromelalgia (2012) (1)
- Contribution of Loss of Large Fiber Function to Pain in 2 Samples of Oncology Patients (2019) (1)
- Proenkephalin transgene regulation in the paraventricular nucleus of the hypothalamus by lipopolysaccharide and interleukin-1beta. (1999) (1)
- (322) Detecting brain activity related to pain using near-infrared spectroscopy (2014) (1)
- The Promise of Effective Pain Treatment Outcomes: Rallying Academic Centers to Lead the Charge. (2015) (1)
- Left to themselves: Time to target chronic pain in childhood rare diseases (2021) (1)
- SMART: A statistical framework for optimal design matrix generation with application to fMRI (2009) (1)
- Neuroimaging of pain: Possibilities of objective measurements of analgesic actions in human subjects (2003) (1)
- Measuring “pain load” during general anesthesia (2022) (1)
- Inadequately Explained Chronic Dry Eye Symptoms and Corneal Pain: New Insights and Concepts (2014) (1)
- Chapter 8.1:Imaging as a CNS Biomarker (2011) (1)
- DTI and MTR Measures of Nerve Fiber Integrity in Pediatric Patients With Ankle Injury (2021) (1)
- Neural response to fear learning in pediatric chronic pain (2018) (1)
- Capturing brain metrics of neuropathic pain using nuclear magnetic resonance. (2013) (1)
- The cornucopia of central disinhibition pain – An evaluation of past and novel concepts (2020) (1)
- Sensitization of Trigeminovascular Pathway (2012) (1)
- fMRI Measures of Drug Modulation of CNS Activation by Noxious Stimuli: Differential effects of a Failed Analgesic (fosaprepitant) vs. an Opioid Analgesic (Buprenorphine) (2009) (1)
- Commentary: Novel Use of Offset Analgesia to Assess Adolescents and Adults with Treatment Resistant Endometriosis-Associated Pain (2020) (1)
- The solitary nucleus connectivity to key autonomic regions in humans (2022) (1)
- Pain stickiness in pediatric complex regional pain syndrome: A role for the nucleus accumbens (2021) (1)
- ADIS: A robust pursuit algorithm for probabilistic and constrained blind source separation (2009) (1)
- Chapter 223 – Neuropathic Pain (2003) (1)
- Altered anterior insula functional connectivity in adolescent and young women with endometriosis-associated pain: Pilot resting-state fMRI study. (2022) (1)
- Integrated Features for Optimizing Machine Learning Classifiers of Pediatric and Young Adults With a Post-Traumatic Headache From Healthy Controls (2022) (0)
- Probing white matter microstructure in youth with chronic pain (2021) (0)
- Pre-treatment non-ictal cephalic allodynia identifies responders to prophylactic treatment of chronic and episodic migraine patients with galcanezumab: A prospective quantitative sensory testing study (NCT04271202). (2023) (0)
- Noxious heat stimuli activate nucleus accumbens (2001) (0)
- Caudal Medulla of the Rat Tract Neurons in the Upper Cervical Spinal Cord and Trigeminohypothalamic and Reticulohypothalamic (2015) (0)
- De Novo CNS Activation following Infusion of Fosaprepitant (NK-1 antagonist) in Healthy Human Subjects (2009) (0)
- relief) in rats and humans cingulate cortex to pain onset (aversion) and offset Analogous responses in the nucleus accumbens and (2015) (0)
- Recurrent ulceration and hypergastrinaemia in the gastrectomized patient. An approach to diagnosis. (1983) (0)
- Common hippocampal structural and functional changes in migraine (2012) (0)
- Functional Brain Imaging in Migraine (2015) (0)
- Galcanezumab effects on incidence of headache after occurrence of triggers, premonitory symptoms, and aura in responders, non-responders, super-responders, and super non-responders (2023) (0)
- Network Effects of Brain Lesions Causing Central Poststroke Pain (2022) (0)
- Pain Imaging: Progress in Pain Research and Management, Volume 18: Edited by Kenneth L. Casey and M. Catherine Bushnell Published by International Association for the Study of Pain, Seattle, Washington, USA, 2000 239 pages, $89.00 (Hardcover) (2002) (0)
- A mean field theory (MFT) approach to fMRI analysis reveals multiphasic activation in response to pain (2000) (0)
- Evidence of Chronic Complement Activation in Asymptomatic Pediatric Brain Injury Patients: A Pilot Study (2022) (0)
- Dissecting Salience Network Responsivity to Evoked Nociception and Pain: Model Free Analyses (2021) (0)
- The Future of Imaging in Migraine Diagnosis and Treatment (2012) (0)
- Structural Brain Changes Are Associated with Pain Sensitivity in New Daily Persistent Headache (2022) (0)
- (756): Case-control study on risk factors for prescription opioid abuse among patients with pain (2007) (0)
- Brain resting-state connectivity in the development of secondary hyperalgesia in healthy men (2019) (0)
- Application of painDETECT in Pediatric Chronic Pain: How Well Does It Identify Neuropathic Pain and Its Characteristics? (2022) (0)
- Reply Adverse Reactions to Nonindicated Medications (1997) (0)
- Imaging Pain and Headache (2017) (0)
- Pulvinar activation in a case of congenital idiopathic photophobia (2019) (0)
- ProcessingLateralization of Somatosensory (2015) (0)
- Alterations of Excitatory Neurotransmitter Systems in Brain Regions of Acute Migraine Patients during the Interictal State (2008) (0)
- Acknowledgement of reviewers 2011 (2011) (0)
- Author Correction: Metabolic and Addiction Indices in Patients on Opioid Agonist Medication-Assisted Treatment: A Comparison of Buprenorphine and Methadone (2020) (0)
- Headache Professional Societies: Ethical Challenges and Suggested Solutions (2017) (0)
- Stimuli in Healthy Volunteers Infusion and Subsequent Mild Noxious Thermal FMRI Measurement of CNS Responses to Naloxone (2015) (0)
- Towards a deeper understanding of pain: How machine learning and deep learning algorithms are needed to provide the next generation of pain medicine for use in the clinic (2022) (0)
- (219) Regional brain structure differences in learning, motivation, and emotion between treatment responders and non-responders in pediatric CRPS. (2016) (0)
- 309) Evoked brain response to fearful faces in pediatric complex regional pain syndrome (CRPS) (2015) (0)
- Can Imaging Change Migraine Treatment Paradigms (2012) (0)
- Chemical Stimulation of the Subarachnoid Space Recordings From Brain Stem Neurons Responding to (2015) (0)
- Contextual Processing and its Alterations in Patients with Addictive Disorders (2023) (0)
- Pre-Treatment Cephalic Interictal Allodynia Predicts Outcome of Prophylactic Treatment of Chronic and Episodic Migraine Patients with Galcanezumab: A Prospective Quantitative Sensory Testing Study (S47.008) (2023) (0)
- Acknowledgement to reviewers 2008 (2009) (0)
- Imaging of Migraine (2015) (0)
- Inflaming the Brain: CRPS a Model Disease to Understand Neuroimmune Interactions in Chronic Pain (2012) (0)
- Reviewer List for 2007 (2007) (0)
- Reply to Letter: "Surgically Induced Neuropathic Pain: Understanding the Perioperative Process". (2015) (0)
- Genetic Addiction Risk Testing Coupled with Pro-Dopamine Homeostasis, and Electro Therapy, May Overcome Aberrant Reward Seeking Behaviors: Analytic Evidence (2018) (0)
- ADVERSE REACTIONS TO NONINDICATED MEDICATIONS. AUTHORS' REPLY (1997) (0)
- 493) The influence of fear level on structural brain changes in Pediatric Complex Regional Pain Syndrome (2015) (0)
- Towards a Clinical Measure of Pain: Hemodynamic Brain Responses to Pain measured by Near-Infrared Spectroscopy (2016) (0)
- Green light alleviates migraine photophobia (S47.005) (2017) (0)
- DE NOVO BUPRENORPHINE PHMRI EFFECTS IN CONSCIOUS RATS PARALLELS BRAIN ACTIVATION IN HUMANS (2010) (0)
- Modified Addiction Center Research Inventory (2015) (0)
- Metabolic and Addiction Indices in Patients on Opioid Agonist Medication-Assisted Treatment: A Comparison of Buprenorphine and Methadone (2020) (0)
- Analgesia after Dorsal Root Ganglionic injection under CT-guidance in a patient with intractable phantom limb pain. (2023) (0)
- The Omnipresence of Autonomic Modulation in Health and Disease (2022) (0)
- Ocular neuropathic pain The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2015) (0)
- pediatric CRPS Habenula functional resting-state connectivity in (2015) (0)
- The effects of KRN5500, a spicamycin derivative, on neuropathic and nociceptive pain models in rats. (Massachusetts General Hospital, Charlestown, MA) Anesth Analg 2000;91:955–959. (2001) (0)
- CircuitryDelay in Sensory But Not Emotion CNS Activation by Noxious Heat to the Hand or Foot (2013) (0)
- Cutaneous Allodynia in a Rat Model of Migraine Stimulation Reflect Central Sensitization and Cardiovascular and Neuronal Responses to Head (2015) (0)
- Alterations In Resting-State Low-Frequency Fluctuation In Patients With Surgically Confirmed Endometriosis (2023) (0)
- 264) Impaired contingency learning in youth with chronic pain (2017) (0)
- Efficacy of Valproate in Manic-Depressive Psychosis: Mechanism of Action and Implications for Pathophysiology (1985) (0)
- Galcanezumab effects on incidence of headache after occurrence of triggers, prodromes, and aura in responders, non-responders, super-responders and super non-responders (P12-12.012) (2023) (0)
- Placebos and Nocebos in Migraine: Children and Adolescents (2019) (0)
- Pain Stickiness in Complex Regional Pain Syndrome: A role for the Nucleus Accumbens (2019) (0)
- Functional Magnetic Resonance Imaging in Drug Development (2010) (0)
- involvement of transient receptor potential channels neurons implicated in basal tearing in rats: Ocular dryness excites two classes of corneal afferent (2015) (0)
- 456 Structural and Functional Brain Changes in Adolescents With Irritable Bowel Syndrome (2016) (0)
- Pain Comes of Age: A More Rational Scientific Approach to Treating Patients (2002) (0)
- Reproducible Piriformis Injection Methodology by Fluoroscopic and Electromyographic Guidance (1998) (0)
- Visceral Pain: A Distinct Neurologic Entity (1999) (0)
- NEUROPATHIC PAIN SECTION Original Research Article A fMRI Evaluation of Lamotrigine for the Treatment of Trigeminal Neuropathic Pain: Pilot Study (2016) (0)
- Rapid treatment-induced brain changes in pediatric CRPS (2014) (0)
- 447 DOES TREATING THE PAIN HEAL THE BRAIN? ANATOMICAL AND FUNCTIONAL CHANGES IN PEDIATRIC COMPLEX REGIONAL PAIN SYNDROME AFTER MULTIDISCIPLINARY TREATMENT (2010) (0)
- Pain and neurological diseases Disease Prevalence of pain Pain symptoms Co-morbid depression Degenerative Parkinson ’ s disease (2012) (0)
- Author Correction: Metabolic and Addiction Indices in Patients on Opioid Agonist Medication-Assisted Treatment: A Comparison of Buprenorphine and Methadone (2020) (0)
- Isolating Brain Regions Implicated in the Affective Components of Neuropathic Pain (2019) (0)
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What Schools Are Affiliated With David Borsook?
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