David Botstein

Q: What Schools Are Affiliated With David Botstein

David Botstein is affiliated with the following schools: Harvard University, University of Vermont, University of Oslo, University of Hong Kong, University of Tokyo, University of Michigan, Princeton University, Stanford University, Massachusetts Institute of Technology, Baylor College of Medicine, Cornell University, National Taiwan University

David Botstein's AcademicInfluence.com Rankings

David Botstein

Biology

#227

World Rank

#414

Historical Rank

#132

USA Rank

Molecular Biology

#51

World Rank

#52

Historical Rank

#36

USA Rank

Genetics

#39

World Rank

#64

Historical Rank

#28

USA Rank

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Biology

Why Is David Botstein Influential?

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According to Wikipedia, David Botstein is an American biologist serving as the chief scientific officer of Calico. He served as the director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University from 2003 to 2013, where he remains an Anthony B. Evnin Professor of Genomics.

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David Botstein's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Gene Ontology: tool for the unification of biology (2000) (34828)
Cluster analysis and display of genome-wide expression patterns. (1998) (16936)
Molecular portraits of human breast tumours (2000) (14829)
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications (2001) (10949)
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling (2000) (9767)
Construction of a genetic linkage map in man using restriction fragment length polymorphisms. (1980) (7885)
Repeated observation of breast tumor subtypes in independent gene expression data sets (2003) (5412)
Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. (1998) (5332)
Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. (1989) (5316)
Genomic expression programs in the response of yeast cells to environmental changes. (2000) (4895)
Missing value estimation methods for DNA microarrays (2001) (3484)
Exploring the new world of the genome with DNA microarrays (1999) (2562)
Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource (2004) (2444)
Advanced bacterial genetics (1980) (2390)
Systematic variation in gene expression patterns in human cancer cell lines (2000) (2228)
The transcriptional program in the response of human fibroblasts to serum. (1999) (2092)
Singular value decomposition for genome-wide expression data processing and modeling. (2000) (2023)
The transcriptional program of sporulation in budding yeast. (1998) (1984)
Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data (2003) (1826)
GO: : TermFinder--open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes (2004) (1821)
Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease (2003) (1576)
Identification of genes periodically expressed in the human cell cycle and their expression in tumors. (2002) (1529)
Genome-wide analysis of DNA copy-number changes using cDNA microarrays (1999) (1510)
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. (1999) (1478)
A gene expression database for the molecular pharmacology of cancer (2000) (1461)
Gene expression profiling identifies clinically relevant subtypes of prostate cancer. (2004) (1350)
Diversity of gene expression in adenocarcinoma of the lung (2001) (1320)
Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase (1982) (1289)
Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia (2001) (1215)
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors (2002) (1200)
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF (2001) (1191)
SGD: Saccharomyces Genome Database (1998) (1106)
A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. (1987) (1101)
Diversity, topographic differentiation, and positional memory in human fibroblasts (2002) (1065)
Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds (2004) (967)
Homozygosity mapping: a way to map human recessive traits with the DNA of inbred children. (1987) (931)
Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. (2004) (927)
A genetic linkage map of the human genome (1987) (882)
Gene expression patterns in human liver cancers. (2002) (871)
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer (1998) (834)
Sterile host yeasts (SHY): a eukaryotic system of biological containment for recombinant DNA experiments. (1979) (827)
A common language for physical mapping of the human genome. (1989) (817)
Saccharomyces Genome Database. (2002) (802)
Advanced Bacterial Genetics: A Manual for Genetic Engineering (1980) (786)
The Gene Ontology project in 2008 (2007) (741)
Endothelial cell diversity revealed by global expression profiling (2003) (729)
DNA topoisomerase II is required at the time of mitosis in yeast (1985) (672)
Promoter-specific binding of Rap1 revealed by genome-wide maps of protein–DNA association (2001) (654)
The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery (1988) (627)
'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns (2000) (625)
Genome-wide analysis of DNA copy number variation in breast cancer using DNA microarrays (1999) (601)
A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae) (2003) (597)
Molecular characterisation of soft tissue tumours: a gene expression study (2002) (597)
Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. (2002) (591)
Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. (2001) (581)
The Stanford Microarray Database (2001) (569)
Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae (2002) (567)
Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast. (2008) (559)
Genetic engineering in vivo using translocatable drug-resistance elements. New methods in bacterial genetics. (1977) (543)
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. (1998) (541)
Plasmid construction by homologous recombination in yeast. (1987) (540)
Yeast: An Experimental Organism for 21st Century Biology (2011) (509)
Systematic changes in gene expression patterns following adaptive evolution in yeast. (1999) (508)
Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. (2005) (508)
Phenotypic analysis of temperature-sensitive yeast actin mutants (1985) (503)
Pervasive Genetic Hitchhiking and Clonal Interference in 40 Evolving Yeast Populations (2013) (486)
Yeast as a Model Organism (1997) (473)
SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data (2003) (466)
The Gene Ontology in 2010: extensions and refinements (2009) (449)
Stereotyped and specific gene expression programs in human innate immune responses to bacteria (2002) (447)
Comparison of the complete protein sets of worm and yeast: orthology and divergence. (1998) (442)
Mutants of yeast defective in sucrose utilization. (1981) (438)
The Repertoire and Dynamics of Evolutionary Adaptations to Controlled Nutrient-Limited Environments in Yeast (2008) (437)
Different gene expression patterns in invasive lobular and ductal carcinomas of the breast. (2004) (432)
A THEORY OF MODULAR EVOLUTION FOR BACTERIOPHAGES * (1980) (421)
The Gene Ontology Consortium (2000) (419)
Genome-wide Analysis of Gene Expression Regulated by the Calcineurin/Crz1p Signaling Pathway in Saccharomyces cerevisiae * (2002) (414)
Systemic and cell type-specific gene expression patterns in scleroderma skin (2003) (410)
Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane (1994) (397)
Isolation of the β-tubulin gene from yeast and demonstration of its essential function in vivo (1983) (386)
Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO) (2002) (383)
Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth (2000) (380)
The Stanford Microarray Database: data access and quality assessment tools (2003) (379)
Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae (2006) (378)
Cold-sensitive cell-division-cycle mutants of yeast: isolation, properties, and pseudoreversion studies. (1982) (378)
Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation (2002) (372)
Genetic and physical maps of Saccharomyces cerevisiae. (1997) (371)
Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. (1995) (366)
High-throughput genotyping with single nucleotide polymorphisms. (2001) (365)
A deletion map of the human Y chromosome based on DNA hybridization. (1986) (360)
Nonparametric methods for identifying differentially expressed genes in microarray data (2002) (338)
Gene expression patterns in ovarian carcinomas. (2003) (333)
Systematic mutational analysis of the yeast ACT1 gene. (1992) (327)
Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms (2003) (325)
Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. (1993) (325)
DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage (1989) (322)
ADP-ribosylation factor is functionally and physically associated with the Golgi complex. (1990) (321)
Diverse effects of beta-tubulin mutations on microtubule formation and function (1988) (321)
The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response. (2003) (318)
Variation in gene expression patterns in human gastric cancers. (2003) (316)
Saccharomyces Genome Database (SGD) provides tools to identify and analyze sequences from Saccharomyces cerevisiae and related sequences from other organisms (2004) (315)
Many random sequences functionally replace the secretion signal sequence of yeast invertase. (1987) (313)
A rapid, efficient method for isolating DNA from yeast. (1986) (309)
Diverse and specific gene expression responses to stresses in cultured human cells. (2004) (300)
Yeast actin-binding proteins: evidence for a role in morphogenesis (1988) (299)
Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast. (2000) (298)
Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition. (1975) (296)
Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression (1991) (296)
A group of interacting yeast DNA replication genes. (1991) (296)
Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. (2000) (290)
Yeast: an experimental organism for modern biology. (1988) (289)
[9] Construction and use of gene fusions to lacZ (β-galactosidase) that are expressed in yeast (1983) (289)
Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. II. Properties of a high-frequency-transducing lysate. (1972) (287)
Mechanism of head assembly and DNA encapsulation in Salmonella phage p22. I. Genes, proteins, structures and DNA maturation. (1973) (287)
Suppressors of yeast actin mutations. (1989) (279)
Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy. (1992) (278)
Movement of yeast cortical actin cytoskeleton visualized in vivo. (1996) (278)
The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. (1999) (272)
Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I (1990) (269)
Lethal disruption of the yeast actin gene by integrative DNA transformation. (1982) (265)
A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds (2009) (264)
Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity. (1993) (263)
Secretion of beta-lactamase requires the carboxy end of the protein (1980) (263)
Gene Ontology annotations at SGD: new data sources and annotation methods (2007) (259)
Conservation of the metabolomic response to starvation across two divergent microbes (2006) (259)
Genetically essential and nonessential alpha-tubulin genes specify functionally interchangeable proteins (1986) (257)
Genome-Wide Detection of Polymorphisms at Nucleotide Resolution with a Single DNA Microarray (2006) (252)
Functional Analysis of the Genes of Yeast Chromosome V by Genetic Footprinting (1996) (250)
Imputing Missing Data for Gene Expression Arrays (2001) (249)
The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase. (1992) (248)
Molecular genetics of bacteriophage P22. (1978) (243)
A DNA microarray survey of gene expression in normal human tissues (2005) (242)
Transformation of follicular lymphoma to diffuse large-cell lymphoma: Alternative patterns with increased or decreased expression of c-myc and its regulated genes (2002) (241)
Structure and function of the yeast URA3 gene: expression in Escherichia coli. (1984) (235)
Introductory Science and Mathematics Education for 21st-Century Biologists (2004) (234)
Growth-limiting Intracellular Metabolites in Yeast Growing under Diverse Nutrient Limitations (2010) (233)
DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli. (2000) (226)
Systems-level analysis of mechanisms regulating yeast metabolic flux (2016) (226)
Occurrence of a transposition from the X-chromosome long arm to the Y-chromosome short arm during human evolution (1984) (225)
ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes (1990) (224)
Defining protein interactions with yeast actin in vivo (1995) (222)
Requirement of yeast fimbrin for actin organization and morphogenesis in vivo (1991) (221)
Simple Mendelian inheritance of the reiterated ribosomal DNA of yeast. (1977) (220)
Comparing whole genomes using DNA microarrays (2008) (218)
A suppressor of SNF1 mutations causes constitutive high-level invertase synthesis in yeast. (1984) (218)
A manic depressive history (1996) (216)
Supervised harvesting of expression trees (2001) (215)
Subcellular localization of yeast CDC46 varies with the cell cycle. (1990) (211)
Host/vector interactions which affect the viability of recombinant phage lambda clones. (1986) (210)
Mechanism of head assembly and DNA encapsulation in Salmonella phage P22. II. Morphogenetic pathway. (1973) (208)
Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins. (1975) (203)
Two functional alpha-tubulin genes of the yeast Saccharomyces cerevisiae encode divergent proteins (1986) (202)
Non-random circular permutation of phage P22 DNA. (1974) (201)
Evidence for transcriptional regulation of orotidine-5'-phosphate decarboxylase in yeast by hybridization of mRNA to the yeast structural gene cloned in Escherichia coli. (1979) (199)
Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes. (1990) (199)
Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. (2003) (199)
BIM1 encodes a microtubule-binding protein in yeast. (1997) (198)
Analysis of topoisomerase function in bacterial replication fork movement: use of DNA microarrays. (2000) (197)
Mapping complex genetic traits in humans: new methods using a complete RFLP linkage map. (1986) (195)
High resolution analysis of functional determinants on human tissue-type plasminogen activator. (1991) (187)
Structure of the yeast endoplasmic reticulum: Localization of ER proteins using immunofluorescence and immunoelectron microscopy (1991) (185)
Aip3p/Bud6p, a yeast actin-interacting protein that is involved in morphogenesis and the selection of bipolar budding sites. (1997) (183)
Strategies for studying heterogeneous genetic traits in humans by using a linkage map of restriction fragment length polymorphisms. (1986) (183)
Properties of the translocatable tetracycline-resistance element Tn10 in Escherichia coli and bacteriophage lambda. (1978) (183)
Desferrioxamine-mediated Iron Uptake in Saccharomyces cerevisiae (2000) (182)
Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae. (1988) (181)
Strategies and applications of in vitro mutagenesis. (1985) (181)
Genetic Variation and the Fate of Beneficial Mutations in Asexual Populations (2011) (179)
Genetic analysis of the yeast cytoskeleton. (1987) (178)
Nutritional homeostasis in batch and steady-state culture of yeast. (2004) (176)
Homeostatic adjustment and metabolic remodeling in glucose-limited yeast cultures. (2005) (176)
Construction and genetic characterization of temperature-sensitive mutant alleles of the yeast actin gene. (1984) (174)
Genetic footprinting: a genomic strategy for determining a gene's function given its sequence. (1995) (172)
A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. (2002) (170)
Universal Reference RNA as a standard for microarray experiments (2004) (169)
Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis (2002) (168)
Misfolded Proteins Are Competent to Mediate a Subset of the Responses to Heat Shock in Saccharomyces cerevisiae * 210 (2002) (166)
Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function. (1990) (166)
Single-copy sequence hybridizes to polymorphic and homologous loci on human X and Y chromosomes. (1982) (165)
RERG Is a Novel ras-related, Estrogen-regulated and Growth-inhibitory Gene in Breast Cancer* (2001) (163)
Large-scale identification of secreted and membrane-associated gene products using DNA microarrays (1999) (162)
Three Cell Wall Mannoproteins Facilitate the Uptake of Iron in Saccharomyces cerevisiae * (2001) (160)
GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction. (1990) (160)
Variation in gene expression patterns in follicular lymphoma and the response to rituximab (2003) (158)
Extrachromosomal circular DNA is common in yeast (2015) (158)
Isolation and Characterization of Mutations in the β-Tubulin Gene of SACCHAROMYCES CEREVISIAE (1985) (157)
The cost of gene expression underlies a fitness trade-off in yeast (2009) (157)
A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation. (1989) (156)
Nomenclature of transposable elements in prokaryotes. (1979) (155)
Characterization of amber and ochre suppressors in Salmonella typhimurium (1979) (154)
The secreted form of invertase in Saccharomyces cerevisiae is synthesized from mRNA encoding a signal sequence (1983) (154)
NDC1: a nuclear periphery component required for yeast spindle pole body duplication (1993) (152)
Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. (2003) (150)
Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12 (2003) (149)
Synthesis and maturation of phage P22 DNA. I. Identification of intermediates. (1968) (149)
Slow growth induces heat-shock resistance in normal and respiratory-deficient yeast. (2008) (146)
Properties of hybrids between Salmonella phage P22 and coliphage λ (1974) (145)
Diverse essential functions revealed by complementing yeast calmodulin mutants. (1994) (142)
Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast (2012) (140)
Ammonium Toxicity and Potassium Limitation in Yeast (2006) (139)
Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer (2006) (136)
Evidence for posttranslational translocation of β-lactamase across the bacterial inner membrane (1982) (134)
Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. (2003) (133)
Role of thioredoxin reductase in the Yap1p‐dependent response to oxidative stress in Saccharomyces cerevisiae (2001) (132)
A gene required for the separation of chromosomes on the spindle apparatus in yeast (1986) (132)
Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. I. Transduction of R factor 222 by phage P22. (1972) (131)
Saccharomyces Genome Database provides mutant phenotype data (2009) (128)
A recombination function essential to the growth of bacteriophage P22. (1970) (128)
Yeast genes fused to beta-galactosidase in Escherichia coli can be expressed normally in yeast. (1981) (128)
Yeast actin cytoskeleton mutants accumulate a new class of Golgi-derived secretary vesicle. (1997) (127)
Influence of genotype and nutrition on survival and metabolism of starving yeast (2008) (127)
Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae (2011) (126)
Principles and Practice of Recombinant DNA Research with Yeast (1982) (126)
Overview of the Alliance for Cellular Signaling (2002) (125)
Coupling among growth rate response, metabolic cycle, and cell division cycle in yeast (2011) (125)
Evolution of the Lambdoid Phages (1983) (124)
Molecular genetics of bacteriophage P22 (1978) (123)
Structure-function relationships in yeast tubulins. (2000) (120)
Diverse effects of methylseleninic acid on the transcriptional program of human prostate cancer cells. (2003) (119)
Genome-Wide Analysis of Nucleotide-Level Variation in Commonly Used Saccharomyces cerevisiae Strains (2007) (119)
Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium. III. Failure of superinfecting phage DNA to enter sieA+ lysogens. (1974) (119)
Inversions and deletions of the Salmonella chromosome generated by the translocatable tetracycline resistance element Tn10. (1979) (117)
Genetics of bacteriophage P22. II. Gene order and gene function. (1972) (116)
The residual enzymatic phosphorylation activity of hexokinase II mutants is correlated with glucose repression in Saccharomyces cerevisiae. (1989) (115)
Statement on use of DNA testing for presymptomatic identification of cancer risk. National Advisory Council for Human Genome Research. (1994) (115)
Inference of combinatorial regulation in yeast transcriptional networks: a case study of sporulation. (2005) (114)
Integrating functional genomic information into the Saccharomyces Genome Database (2000) (113)
Effects of null mutations in the hexokinase genes of Saccharomyces cerevisiae on catabolite repression (1986) (112)
Clustering methods for the analysis of DNA microarray data (1999) (111)
The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response. (1987) (111)
Orthology and functional conservation in eukaryotes. (2007) (110)
Predicting Cellular Growth from Gene Expression Signatures (2009) (110)
Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4 (1993) (109)
Construction and use of gene fusions to lacZ (beta-galactosidase) that are expressed in yeast. (1983) (109)
Genetic properties of chromosomally integrated 2μ plasmid DNA in yeast (1982) (109)
T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression (2003) (108)
Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium. II. Genetic evidence for two exclusion systems. (1971) (107)
Dissemination of an antibiotic resistance plasmid in hospital patient flora (1980) (107)
Organization of the SUC gene family in Saccharomyces (1983) (107)
The Princeton Protein Orthology Database (P-POD): A Comparative Genomics Analysis Tool for Biologists (2007) (106)
A genetic method for determining the order of events in a biological pathway. (1973) (105)
Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes (2013) (104)
Saccharomyces cerevisiae S288C genome annotation: a working hypothesis (2006) (103)
Packaging of an oversize transducing genome by Salmonella phage P22. (1974) (103)
Diverse effects of mutations in the signal sequence on the secretion of β-lactamase in Salmonella typhimurium (1982) (101)
Saccharomyces genome database: Underlying principles and organisation (2004) (100)
Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function (2011) (99)
Genetics of bacteriophage P22. I. Isolation of prophage deletions which affect immunity to superinfection. (1972) (98)
Genome Snapshot: a new resource at the Saccharomyces Genome Database (SGD) presenting an overview of the Saccharomyces cerevisiae genome (2005) (98)
Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate (2010) (98)
Mechanism of action of Salmonella phage P22 antirepressor. (1975) (97)
Transcriptional response of steady-state yeast cultures to transient perturbations in carbon source. (2006) (96)
Isolation and characterization of conditional-lethal mutations in the TUB1 alpha-tubulin gene of the yeast Saccharomyces cerevisiae. (1988) (95)
Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus (2010) (95)
A systematic approach to reconstructing transcription networks in Saccharomyces cerevisiae (2002) (94)
Two alanine racemase genes in Salmonella typhimurium that differ in structure and function (1983) (92)
Generalized transduction by phage P22 in Salmonella typhimurium. I. Molecular origin of transducing DNA. (1972) (91)
Propagation of some human DNA sequences in bacteriophage lambda vectors requires mutant Escherichia coli hosts. (1985) (91)
Yeast proteins associated with microtubules in vitro and in vivo. (1992) (90)
Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. (2003) (90)
Genome-Scale Identification of Membrane-Associated Human mRNAs (2006) (90)
Metabolic cycling without cell division cycling in respiring yeast (2011) (89)
Catabolic alanine racemase from Salmonella typhimurium: DNA sequence, enzyme purification, and characterization. (1984) (89)
A Tn10-lacZ-kanR-URA3 gene fusion transposon for insertion mutagenesis and fusion analysis of yeast and bacterial genes. (1987) (88)
Probing Lymphocyte Biology by Genomic-Scale Gene Expression Analysis (1998) (87)
Visualization of receptor-mediated endocytosis in yeast. (1999) (87)
CDC46/MCM5, a yeast protein whose subcellular localization is cell cycle-regulated, is involved in DNA replication at autonomously replicating sequences. (1992) (87)
Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiae (2014) (86)
Secretion-defective mutations in the signal sequence for Saccharomyces cerevisiae invertase (1986) (86)
Expanded protein information at SGD: new pages and proteome browser (2006) (84)
Specificity of genetic elements controlling regulation of early functions in temperate bacteriophages. (1976) (84)
Genetic approaches to the analysis of microbial development. (1982) (83)
System-Level Analysis of Genes and Functions Affecting Survival During Nutrient Starvation in Saccharomyces cerevisiae (2011) (80)
Dominant suppressors of yeast actin mutations that are reciprocally suppressed. (1989) (80)
A rapid chromosome-mapping method for cloned fragments of yeast DNA. (1983) (79)
Transcriptional response of human mast cells stimulated via the FcεRI and identification of mast cells as a source of IL-11 (2002) (79)
Manipulating yeast genome using plasmid vectors. (1990) (79)
Of Genes and Genomes (1999) (77)
Saccharomyces Genome Database (SGD) provides biochemical and structural information for budding yeast proteins (2003) (77)
Structure and function of the yeast URA3 gene. Differentially regulated expression of hybrid beta-galactosidase from overlapping coding sequences in yeast. (1983) (76)
Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype. (2000) (75)
Gene Shaving: a new class of clustering methods for expression arrays (2000) (73)
Disruption of yeast forkhead-associated cell cycle transcription by oxidative stress. (2004) (71)
Isolation and analysis of recombinant DNA molecules containing yeast DNA. (1978) (70)
Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporter (2015) (70)
Saccharomyces Genome Database provides tools to survey gene expression and functional analysis data (2001) (69)
Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p. (1993) (67)
Structure and assembly of the capsid of bacteriophage P22. (1976) (66)
Identification of amino acid substitutions that alter the substrate specificity of TEM-1 beta-lactamase (1992) (66)
Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. (2000) (65)
Determination of the order of gene function in the yeast nuclear division pathway using cs and ts mutants. (1982) (64)
Yeast actin filaments display ATP-dependent sliding movement over surfaces coated with rabbit muscle myosin. (1992) (63)
Regulation of HIS4-lacZ fusions in Saccharomyces cerevisiae (1982) (63)
Encapsulation of phage P22 DNA in vitro. (1979) (62)
Probing β‐lactamase structure and function using random replacement mutagenesis (1992) (62)
Directed mutagenesis with sodium bisulfite. (1983) (62)
Using the Saccharomyces Genome Database (SGD) for analysis of protein similarities and structure (1999) (61)
Specificity of insertion by the translocatable tetracycline-resistance element Tn10. (1979) (60)
Superinfection exclusion by λ prophage in lysogens ofSalmonella typhimurium (1971) (60)
Isolation, cloning, and sequencing of the Salmonella typhimurium ddlA gene with purification and characterization of its product, D-alanine:D-alanine ligase (ADP forming). (1988) (60)
Identification of more than 500 RFLPs by screening random genomic clones. (1988) (60)
A genome scan for hypertension susceptibility loci in populations of Chinese and Japanese origins. (2003) (59)
Recurated protein interaction datasets (2009) (58)
Yeast suppressors of UAA and UAG nonsense codons work efficiently in vitro via tRNA (1976) (58)
Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD) (2004) (58)
Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. (2000) (57)
Genetic variation in aldosterone synthase predicts plasma glucose levels (2001) (57)
Systematic mutagenesis of the yeast mating pheromone receptor third intracellular loop. (1994) (56)
Transformation of yeast with linearized plasmid DNA. Formation of inverted dimers and recombinant plasmid products. (1985) (56)
Identification of alterations in DNA copy number in host stromal cells during tumor progression (2006) (55)
Gap misrepair mutagenesis: efficient site-directed induction of transition, transversion, and frameshift mutations in vitro. (1982) (55)
Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium. IV. Genetics and physiology of sieB exclusion. (1974) (54)
Changing perspectives in yeast research nearly a decade after the genome sequence. (2005) (54)
Intermediates in the synthesis of phage P22 DNA. (1968) (53)
Regional specificity of illegitimate recombination by the translocatable ampicillin-resistance element Tn1 in the genome of phage P22. (1979) (53)
Identification, cloning and sequence determination of the genes specifying hexokinase A and B from yeast. (1986) (52)
The glycine allele of a glycine/arginine polymorphism in the beta2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin. (2001) (52)
Conditional lethality of a yeast strain expressing human RHOA in place of RHO1. (1994) (51)
Biosynthetic alr alanine racemase from Salmonella typhimurium: DNA and protein sequence determination. (1986) (51)
Isolation and characterization of mutations in the beta-tubulin gene of Saccharomyces cerevisiae. (1985) (48)
Molecular sequence accuracy and the analysis of protein coding regions. (1991) (48)
Homologous Recombination between Episomal Plasmids and Chromosomes in Yeast. (1983) (47)
Synthesis and maturation of phage P22 DNA. II. Properties of temperature-sensitive phage mutants defective in DNA metabolism. (1968) (46)
Microarrays in primary breast cancer--lessons from chemotherapy studies. (2001) (45)
Structure-based systematic isolation of conditional-lethal mutations in the single yeast calmodulin gene. (1994) (45)
Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes (2010) (45)
Processing and modeling genome-wide expression data using singular value decomposition (2001) (45)
Segment-directed mutagenesis: construction in vitro of point mutations limited to a small predetermined region of a circular DNA molecule. (1980) (45)
A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes (2012) (45)
Purification and properties of proteins essential to DNA encapsulation by phage P22. (1979) (45)
TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae (2013) (44)
Fine structure recombinational analysis of cloned genes using yeast transformation. (1987) (44)
Dominant-Lethal α-Tubulin Mutants Defective in Microtubule Depolymerization in Yeast (2001) (44)
Genetic evidence for a silent SUC gene in yeast. (1981) (43)
Nomenclature of transposable elements in prokaryotes. (1979) (41)
Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway (2012) (41)
Functional interchangeability of DNA replication genes in Salmonella typhimurium and Escherichia coli demonstrated by a general complementation procedure. (1984) (41)
Genetic variation in the human urea transporter-2 is associated with variation in blood pressure. (2001) (41)
Back to the future: education for systems-level biologists (2006) (41)
Superinfection exclusion by P22 prophage in lysogens of Salmonella typhimurium. 1. Exclusion of generalized transducing particles. (1971) (39)
Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathway (2012) (39)
Insertions of up to 17 amino acids into a region of alpha-tubulin do not disrupt function in vivo (1987) (39)
Generalized transduction by bacteriophage P22 in Salmonella typhimurium. II. Mechanism of integration of transducing DNA. (1972) (38)
Multiple functions for actin during filamentous growth of Saccharomyces cerevisiae. (1998) (37)
A Test of the Coordinated Expression Hypothesis for the Origin and Maintenance of the GAL Cluster in Yeast (2011) (36)
Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression (2013) (36)
Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast (2011) (36)
A locus for Fanconi anemia on 16q determined by homozygosity mapping. (1996) (36)
Nonrandom Mutagenesis of the Escherichia coli Genome by Nitrosoguanidine (1969) (35)
Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells. (2016) (35)
Di erent types of di use large b-cell lymphoma identi ed by gene expression pro ling (2000) (34)
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. (1997) (34)
An early regulatory gene of Salmonella phage P22 analogous to gene N of coliphage lambda. (1975) (33)
Genome-wide Analysis of Gene Expression Regulated by the Calcineurin / Crz 1 p Signaling Pathway in Saccharomyces cerevisiae * (2002) (33)
McClintock Myths. (Book Reviews: The Dynamic Genome. Barbara McClintock's Ideas in the Century of Genetics.) (1992) (33)
Substitution of tyrosine for either cysteine in beta-lactamase prevents release from the membrane during secretion. (1987) (32)
Simple Mendelian inheritance of the repeating yeast ribosomal DNA genes. (1978) (32)
Mutational analysis of the role of hydrophobic residues in the 338-348 helix on actin in actomyosin interactions. (1996) (31)
Specialized transduction by bacteriophage P22 in Salmonella typhimurium: genetic and physical structure of the transducing genomes and the prophage attachment site. (1976) (31)
Transcription Termination and Regulation in Bacteriophages P22 and Lambda (1976) (31)
Molecular linguistics: extracting information from gene and protein sequences. (1997) (30)
Synapsis-mediated fusion of free DNA ends forms inverted dimer plasmids in yeast. (1990) (29)
A new yeast gene with a myosin-like heptad repeat structure (1993) (29)
EXPLORATORY SCREENING OF GENES AND CLUSTERS FROM MICROARRAY EXPERIMENTS (2002) (29)
Efficiency and diversity of protein localization by random signal sequences (1990) (29)
Recessive lethal amber suppressors in yeast. (1975) (29)
1 The Yeast Cytoskeleton (1997) (29)
It's the Data! (2010) (28)
SUC genes of yeast: a dispersed gene family. (1981) (28)
Expression array technology in the diagnosis and treatment of breast cancer. (2002) (28)
Diverse biological functions of small GTP-binding proteins in yeast. (1988) (28)
Substitution of serine caused by a recessive lethal suppressor in yeast. (1976) (27)
Loss of a 20S Proteasome Activator in Saccharomyces cerevisiae Downregulates Genes Important for Genomic Integrity, Increases DNA Damage, and Selectively Sensitizes Cells to Agents With Diverse Mechanisms of Action (2012) (27)
Maize transposable elements: a story in four parts. (1992) (26)
The future of humans as model organisms (2018) (25)
A New System for Comparative Functional Genomics of Saccharomyces Yeasts (2013) (25)
Isolation and characterization of mutations in the HXK2 gene of Saccharomyces cerevisiae (1989) (24)
Missing Value Estimation (2003) (24)
Visualization and Analysis of mRNA Molecules Using Fluorescence In Situ Hybridization in Saccharomyces cerevisiae (2013) (22)
Systematic structure-function analysis of the small GTPase Arf1 in yeast. (2002) (22)
Module Networks : Discovering Regulatory Modules and their Condition Specific Regulators from Gene Expression Data (2003) (22)
GeneXplorer: an interactive web application for microarray data visualization and analysis (2004) (21)
Selection of functional signal peptide cleavage sites from a library of random sequences (1994) (20)
Identification of functional connections between calmodulin and the yeast actin cytoskeleton. (1998) (19)
Genetics of bacteriophage P22. III. The late operon. (1980) (18)
Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast. (2001) (17)
Accumulation of Recessive Lethal Mutations in Saccharomyces cerevisiae mlh1 Mismatch Repair Mutants Is Not Associated With Gross Chromosomal Rearrangements (2006) (16)
A genome-scale yeast library with inducible expression of individual genes (2020) (16)
Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiae (2015) (16)
Why we need more basic biology research, not less (2012) (16)
Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case (2013) (16)
Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data (2010) (16)
Tumor classification using gene expression patterns from DNA microarrays (2000) (16)
NOVEL GENOME-SCALE CORRELATION BETWEEN DNA REPLICATION AND RNA TRANSCRIPTION DURING THE CELL CYCLE IN YEAST IS PREDICTED BY DATA-DRIVEN MODELS (2004) (15)
Simultaneous Profiling of DNA Accessibility and Gene Expression Dynamics with ATAC-Seq and RNA-Seq. (2018) (15)
Automating the construction of gene ontologies (2013) (15)
Genetic analysis of DNA replication in bacteria: dnaB mutations that suppress dnaC mutations and dnaQ mutations that suppress dnaE mutations in Salmonella typhimurium. (1984) (14)
Regional assignments of three polymorphic DNA segments on human chromosome 15 (1986) (14)
Deoxyribonucleic Acid Repair in a Highly Radiation-Resistant Strain of Salmonella typhimurium (1973) (14)
A MODULAR THEORY OF VIRUS EVOLUTION (1980) (14)
Ira Herskowitz: 1946-2003. (2004) (14)
Repression and immunity in Salmonella phages P22 and L: phage L lacks a functional secondary immunity system. (1978) (13)
Immunoelectron microscopy of aldehyde-fixed yeast cells. (2002) (13)
A method for detecting and correcting feature misidentification on expression microarrays (2004) (13)
Novel insights from a multiomics dissection of the Hayflick limit (2022) (13)
Alignment of partial denaturation maps of circularly permuted DNA by computer. (1974) (13)
implications Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical (2001) (12)
The Harvey lectures, Series 82 (1988) (12)
P22 morphogenesis. II: Mechanism of DNA encapsulation. (1974) (12)
Involvement of residues 296-299 in the enzymatic activity of tissue-type plasminogen activator. (1992) (12)
Challenges in developing a molecular characterization of cancer. (2002) (11)
Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast (2018) (11)
Decoding the Language of Genetics (2015) (11)
The 15 N‐terminal amino acids of hexokinase II are not required for in vivo function: Analysis of a truncated form of hexokinase II in Saccharomyces cerevisiae (1989) (11)
Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters (2013) (11)
Regional specificity of illegitimate recombination associated with the translocatable ampicillin-resistance element Tn1. (1979) (11)
Formation of inverted dimer plasmids after transformation of yeast with linearized plasmid DNA. (1984) (11)
Control of lysogenization by phage P22. I. The P22 cro gene. (1981) (11)
Gene Ontology: a controlled vocabulary to describe the function, biological process and cellular location of gene products in genome databases (1999) (11)
Superinfection exclusion by lambda prophage in lysogens of Salmonella typhimurium. (1980) (11)
A genome‐scale yeast library with inducible expression of individual genes (2021) (11)
Why study the cytoskeleton in yeast? (1986) (10)
Universality, specificity and regulation of S. cerevisiae growth rate response in different carbon s (2010) (10)
Regulation of DNA replication during the yeast cell cycle. (1991) (10)
Ordered Linear Tetrads Are Produced by the Sporulation of Newly Formed Zygotes of Saccharomyces cerevisiae. (1987) (9)
The ends of Tn10 are not IS3 (1979) (9)
Control of lysogenization by phage P22. II. Mutations (clyA) in the cl gene that cause increased lysogenization. (1981) (9)
Technological Innovation Leads to Fundamental Understanding in Cell Biology (2010) (8)
Extracting information from protein sequences using random replacement mutagenesis (1991) (8)
Planning the Genome Institute's Future (2003) (8)
Minor Isozymes Tailor Yeast Metabolism to Carbon Availability (2018) (8)
Why yeast? (1991) (7)
Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase. (2018) (7)
Extensive Regulation of Metabolism and Growth during the Cell Division Cycle (2014) (7)
Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual (2020) (7)
Probing beta-lactamase structure and function using random replacement mutagenesis. (1992) (6)
Intragenic revertants of yeast invertase variants with secretion-defective leader sequences (1989) (5)
The residual enzymatic phosphorylation activity of hexokinase II mutants is correlated with glucose repression in Saccharomyces cerevisiae (1989) (5)
Consanguinity and heterogeneity: cystic fibrosis need not be homogeneous in Italy. (1986) (5)
IV. Yeast sequencing reports. Nucleotide sequence of the SAC2 gene of Saccharomyces cerevisiae (1994) (5)
1989 Allen Award address: the American Society of Human Genetics annual meeting, Baltimore. (1990) (5)
Identification of clinically distinct types of diffuse large B-cell lymphoma based on gene expressio (2000) (5)
A cDNA microarray gene expression database for cancer drug discovery (1999) (5)
The molecular biology of color vision. (1986) (5)
GENETIC ANALYSIS OF DNA REPLICATION IN SALMONELLA TYPHIMURIUM (1981) (5)
Correction: A DNA microarray survey of gene expression in normal human tissues (2005) (4)
Genetics of bacteriophage P22. IV. Correlation of genetic and physical map using translocatable drug-resistance elements. (1980) (4)
Single-stranded gaps as localized targets for in vitro mutagenesis. (1982) (4)
Recombinant DNA methods: applications to human genetics. (1988) (4)
Fruits of Genome Sequences for Biology (2011) (4)
Genetic mapping of mutations in a highly radiation-resistant mutant of Salmonella typhimurium LT2 (1982) (3)
Anecdotal, Historical and Critical Commentaries on Genetics (2004) (3)
Phylogenetic Portrait of the Saccharomyces cerevisiae Functional Genome (2013) (3)
Basic References (3)
Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, (6946-6951) 10.1073/pnas.1002422107) (2011) (3)
A Molecular Approach to Defining the Inherited Components in Epilepsy and Other Diseases of Uncertain Etiology (1984) (3)
Revisiting the Hayflick Limit: Insights from an Integrated Analysis of Changing Transcripts, Proteins, Metabolites and Chromatin (2021) (2)
Erratum: Diversity of gene expression in adenocarcinoma of the lung (Proceedings of the National Academy of Sciences of the United States of America (2001) 98 (13784-13789)) (2002) (2)
Genome-scale Identification of Secreted and Membrane-associated Tumor Markers (2005) (2)
A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1 (2020) (2)
Formation of P22 generalized transducing particles in vitro. (1979) (2)
Twenty-five years of transposable element research in Köln. (1992) (2)
GENETIC ANALYSIS OF THE CYTOSKELETON YEAST (1987) (2)
Genome-wide maps of DNA-protein interactions using a yeast ORF and intergenic microarray (1999) (2)
135. Evidence for linkage of bipolar disorder to HC 18 with a parent-of-origin effect (1996) (2)
Functional clustering of genes using microarray gene expression data (1999) (2)
Gene function, metabolic pathways and comparative genomics in yeast (2003) (2)
Considerations affecting the feasibility of mapping a single-gene disorder using restriction fragment polymorphisms, with special reference to ataxia-telangiectasia. (1985) (2)
Genetic Analysis of Cytoskeletal Protein Function in Yeast (1984) (1)
Relation of gene expression-based tumor subclasses to clinical phenotypes (2000) (1)
Mapping the Human Genome Using Restriction Fragment Length Polymorphisms (1985) (1)
Genomic perspective and cancer. (2003) (1)
Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes (1990) (1)
The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response Running title: The role of HSF1 in the heat shock response (2003) (1)
Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases (2020) (1)
Fusions of bacteriophage P22 late genes to the Escherichia coli lacZ gene (1987) (1)
Short Communication Expression of Cytokeratins 17 and 5 Identifies a Group of Breast Carcinomas with Poor Clinical Outcome (2002) (1)
1992 Genetics Society of America Medal: Maynard V. Olson. (1992) (1)
DNA MICROARRAYS AS "MICROSCOPES" FOR WATCHING A GENOME IN ACTION (1998) (1)
Genetics in the post-sequence era. (1993) (1)
Global analysis of the yeast knock-out phenome (2022) (1)
Yeast genes fused to fi-galactosidase in Escherichia coli can be expressed normally in yeast (deletion (1)
Using universal human reference RNA in microarray gene expression studies (2001) (1)
Nonsense suppressor mutants of bacteriophage T5. (1982) (1)
The Saccharomyces Genome Database provides comprehensive information about the biology of S. cerevisiae and tools for studies in comparative genomics (2007) (1)
Pollution Indicators: Pollution Ecology of Freshwater Invertebrates . C. W. Hart, Jr., and Samuel L. H. Fuller, Eds. Academic Press, New York, 1974. xvi, 390 pp., illus. $24.50. Water Pollution. (1975) (0)
Computational Methods and Bioinformatic Tools (2004) (0)
Studying breast cancer on a genomic scale using DNA microarrays (2000) (0)
Editorial Board (2013) (0)
Loss of major nutrient sensing and signaling pathways suppresses starvation lethality in electron transport chain mutants (2021) (0)
Using the Genetic Linkage Map of the Human Genome to Understand Complex Inherited Diseases (1989) (0)
Compositions and methods for the diagnosis and treatment of tumor diseases (2000) (0)
Planning the Genome Institute's future [1] (multiple letters) (2003) (0)
MAKING MUTATIONS IN VITRO AND PUTTING THEM BACK INTO YEAST (1982) (0)
Genes, genomes, and cancer (2005) (0)
02-Chromosome structure and function (2007) (0)
Improving the specificity of biological signal detection from microarray data (2003) (0)
The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response (1987) (0)
Analysis of gene expression in normal and malignant lymphocytes using the Lymphochip cDNA microarray (1999) (0)
A method for preparing a variant of plasmogen activator tissue. (1989) (0)
ISOLATION AND CHARACTERIZATION OF MUTATIONS IN T H E @-TUBULIN GENE OF SACCHAROMYCES CEREVISIAE (2003) (0)
Polymorphisms High-Throughput Genotyping with Single Nucleotide Material (2001) (0)
Homozygosity mapping of Fanconi anemia (1994) (0)
Intellectual Origins of Genomics Genomic Perspective and Cancer (0)
Efficiency andDiversity ofProtein Localization by RandomSignal Sequences (1990) (0)
DcR3 polypeptide, TNFR homologue (1998) (0)
Methods for diagnosis of tumors. (2000) (0)
Abstracts of papers presented at the 1990 Meeting on Function and Evolution of RAS Proteins, May 9-May 13, 1990 (1990) (0)
Editorial Board (2008) (0)
Genomicampli ® cationof a decoy receptor for Fas ligand in lungandcoloncancer (0)
RETROSPECTIVE It's the Data! (2010) (0)
From gene expression to the bedside: A high-throughput approach for identifying serum diagnostic markers and immunotherapy targets in human malignancies using DNA microarrays (2001) (0)
Editorial Board (1981) (0)
The interactions of tissue-type plasminogen activator with fibrin (1994) (0)
0 Distinguished Lecturer Series Distinguished Lecturer Series Duke University Program in Genetics and Genomics (2005) (0)
Broken chromosomes and telomeres. (1992) (0)
Genetic footprinting and functional maps of the yeast genome (1999) (0)
Gap misrepair mutagenesis: Efficie transition, transversion, and frame. (site-specific mutagenesis/base substitutions/DNA polymerase/fide (2016) (0)
Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases. (2020) (0)
Selection ofFunctional Signal Peptide Cleavage Sites froma Library ofRandomSequences (1994) (0)
1989AllenAwardAddress: TheAmerican Society ofHuman Genetics AnnualMeeting, Baltimore (1990) (0)
How the Genome and the Computer Have Transformed Biological Science (2011) (0)
Transcriptional regulation of the yeast orotidine 5'-phosphate decarboxylase gene [proceedings]. (1978) (0)
Bacteriophage P22 gene 23 product acts preferentially in cis (1987) (0)
13 How genomics has reshaped our view of cancer (2010) (0)
Gene Chips: A New Tool for Biology (2005) (0)
Vævsplasminoaktivator- (t-PA) variant with zymogenic or fibrin or plasma clot-specific properties, process for their preparation, DNA sequence encoding the variant, a replicable expression vector for this, and host cells transformed (1991) (0)
The Art and Science of Cell Biology (ASCB 2 ) (2012) (0)
254 exonucleolytic degradation of single and double-stranded DNA , low-level endonucleolytic cleavage of single-stranded DNA (1986) (0)
Secreted and transmembrane polypeptides and nucleic acids to their codes (2000) (0)
P-POD, The Princeton Protein Orthology Database, as a Tool for Identifying Gene Function (2009) (0)
ANALYSIS OF YEAST CELL-CYCLE MUTATIONS BY PSEUDO-REVERSION (1979) (0)
cancer clinical treatment response in locally advanced breast Gene expression profiles do not consistently predict the (2011) (0)
Willing to do the math: an interview with David Botstein. Interview by Jane Gitschier. (2006) (0)
in Yeast Diverse Biological Functions of Small GTP-binding Proteins (2008) (0)
Secreted polypeptides and nucleic acids encoding (1999) (0)
Process for tissue plasminogen activator (t-PA) for preparing and identifying variants (1991) (0)
TwoAlanine Racemase GenesinSalmonella typhimurium ThatDiffer inStructure andFunction (1983) (0)
Lasker∼Koshland to Genetics Pioneer (2014) (0)
Methods for diagnosing tumors (2000) (0)
Reproductive toxicology. Feed restriction in Swiss CD-1 mice. (1997) (0)
DcR3 polypeptide, a homolog of TNFR. (1998) (0)
DNA Topoisomerase II MustActatMitosis ToPrevent Nondisjunction andChromosome Breakage (1989) (0)
Phylogenetic Portrait of the S. cerevisiae Functional Genome (2013) (0)
Discovery of distinctive gene expression profiles in human arthritides by cDNA micro-array analysis (2002) (0)
Palace flags up science (2006) (0)
Composition and method for the diagnosis of tumors (1999) (0)
genome sequence Changing perspectives in yeast research nearly a decade after the (2008) (0)
DNA modification procedures and detection of the effects on the interaction of modified polypeptides and white substrates. (1991) (0)
Update from the DANA consortium on the genetics of bipolar disorder (1996) (0)
McClintock (1933): implications for meiotic chromosome pairing. (1992) (0)
Homologues tie ligands. (1998) (0)
A rapid chromosome mapping method for cloned fragments of yeast saccharomyces cerevisiae dna (1983) (0)
Book Review:Essentials of Bacterial and Viral Genetics. David M. Carlberg (1978) (0)
Genome-wide study of human hepatocellular carcinoma with 23K cDNA microarray (2000) (0)
The mutable waxy and bronze1 alleles of maize. (1992) (0)
Potential role of yeast genetics for industry (1984) (0)

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