David Curtis
#138,175
Most Influential Person Now
Researcher
David Curtis's AcademicInfluence.com Rankings
David Curtiscomputer-science Degrees
Computer Science
#6463
World Rank
#6815
Historical Rank
Artificial Intelligence
#2366
World Rank
#2406
Historical Rank
Database
#3551
World Rank
#3700
Historical Rank

Download Badge
Computer Science
David Curtis's Degrees
- PhD Computer Science Stanford University
Similar Degrees You Can Earn
Why Is David Curtis Influential?
(Suggest an Edit or Addition)David Curtis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological Insights From 108 Schizophrenia-Associated Genetic Loci (2014) (6445)
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs (2013) (2011)
- Rare chromosomal deletions and duplications increase risk of schizophrenia (2008) (1506)
- Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder (2008) (1189)
- A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016) (1125)
- Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder (2017) (998)
- Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder (2017) (998)
- Monte Carlo tests for associations between disease and alleles at highly polymorphic loci (1995) (957)
- The UK10K project identifies rare variants in health and disease (2015) (926)
- Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects (2016) (736)
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders (2019) (724)
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways (2015) (676)
- An extended transmission/disequilibrium test (TDT) for multi‐allele marker loci (1995) (639)
- Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats. (1996) (538)
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
- Model-Free Analysis and Permutation Tests for Allelic Associations (1999) (443)
- Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. (2001) (396)
- Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders (2016) (363)
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022) (361)
- A note on the calculation of empirical P values from Monte Carlo procedures. (2002) (361)
- Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel (2015) (296)
- Meta-analysis of 32 genome-wide linkage studies of schizophrenia (2009) (269)
- Genetic mapping of a major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q. (1997) (256)
- Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology (2021) (240)
- Use of siblings as controls in case‐control association studies (1997) (206)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- A note on the application of the transmission disequilibrium test when a parent is missing. (1995) (184)
- Association between clozapine response and allelic variation in the 5-HT2C receptor gene (1995) (183)
- Allelic variation in the vitamin D receptor influences susceptibility to IDDM in Indian Asians (1997) (182)
- The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability (2017) (182)
- DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder (2009) (178)
- Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study. Schizophrenia Linkage Collaborative Group for Chromosomes 3, 6 and 8. (1996) (175)
- Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23‐q24, and suggests the presence of additional loci on 1p and 1q (2003) (163)
- Rare coding variants in ten genes confer substantial risk for schizophrenia (2022) (154)
- A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia (1998) (137)
- Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia (2017) (129)
- Decreased Hippocampal Expression of a Glutamate Receptor Gene in Schizophrenia (1991) (127)
- Case–control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders (2009) (113)
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia (2017) (107)
- Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1‐q32 (1995) (106)
- Linkage analysis of idiopathic generalized epilepsy (IGE) and marker loci on chromosome 6p in families of patients with juvenile myoclonic epilepsy: no evidence for an epilepsy locus in the HLA region. (1993) (100)
- Catechol-O-methyltransferase Val158Met polymorphism: frequency analysis in Han Chinese subjects and allelic association of the low activity allele with bipolar affective disorder. (1997) (99)
- Genetic evidence for the neuronal nitric oxide synthase gene (NOS1) as a susceptibility locus for infantile pyloric stenosis. (1996) (98)
- Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia. (2006) (98)
- Model-free linkage analysis using likelihoods. (1995) (95)
- Exome sequencing identifies rare coding variants in 10 genes which confer substantial risk for schizophrenia (2020) (94)
- Polygenic risk score for schizophrenia is more strongly associated with ancestry than with schizophrenia (2018) (94)
- Two-locus admixture linkage analysis of bipolar and unipolar affective disorder supports the presence of susceptibility loci on chromosomes 11p15 and 21q22. (1997) (93)
- SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent. (2002) (92)
- Complement genes contribute sex-biased vulnerability in diverse illnesses (2020) (92)
- Haplotype combinations of calpain 10 gene polymorphisms associate with increased risk of impaired glucose tolerance and type 2 diabetes in South Indians. (2002) (88)
- Mutations of the KIT (mast/stem cell growth factor receptor) proto-oncogene account for a continuous range of phenotypes in human piebaldism. (1992) (86)
- A genome‐wide family‐based linkage study of coeliac disease (2000) (86)
- Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3 (2006) (86)
- Linkage findings in bipolar disorder (1995) (83)
- Case–case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes (2011) (83)
- Linkage of Wolfram syndrome to chromosome 4p16.1 and evidence for heterogeneity. (1996) (79)
- Autosomal Dominant Gene Transmission in a Large Kindred with Gilles de la Tourette Syndrome (1992) (76)
- The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. (2005) (74)
- Using risk calculation to implement an extended relative pair analysis (1994) (74)
- Study of Regions of Extended Homozygosity Provides a Powerful Method to Explore Haplotype Structure of Human Populations (2008) (73)
- Cloning of the human dopamine D5 receptor gene and identification of a highly polymorphic microsatellite for the DRD5 locus that shows tight linkage to the chromosome 4p reference marker RAF1P1. (1993) (73)
- A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans (2014) (69)
- Cardiovascular disease risk (1996) (64)
- Application of Logistic Regression to Case-Control Association Studies Involving Two Causative Loci (2005) (60)
- New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. (2015) (58)
- Use of an artificial neural network to detect association between a disease and multiple marker genotypes (2001) (58)
- Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder (2011) (58)
- Haplotype Association Analysis of Discrete and Continuous Traits Using Mixture of Regression Models (2004) (56)
- A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia (2010) (56)
- Genetic association between alleles of pancreatic phospholipase A2 gene and bipolar affective disorder (1995) (56)
- Support of association between BRD1 and both schizophrenia and bipolar affective disorder (2010) (55)
- No Evidence for a Susceptibility Locus Predisposing to Manic Depression in the Region of the Dopamine (D2) Receptor Gene (1991) (55)
- Linkage between tyrosine hydroxylase gene and affective disorder cannot be excluded in two of six pedigrees. (1993) (53)
- Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia (2009) (52)
- Evaluation of the positional candidate gene CHRNA7 at the juvenile myoclonic epilepsy locus (EJM2) on chromosome 15q13–14 (2002) (52)
- CTLA-4/CD28 gene region is associated with genetic susceptibility to coeliac disease in UK families (2002) (50)
- Program Report: GENECOUNTING Support Programs (2006) (50)
- The genetic susceptibility to Gilles de la Tourette Syndrome in a large multiple affected british kindred: Linkage analysis excludes a role for the genes coding for dopamine D1, D2, D3, D4, D5 receptors, dopamine beta hydroxylase, tyrosinase, and tyrosine hydroxylase (1995) (49)
- Exclusion of the 5-HT1A serotonin neuroreceptor and tryptophan oxygenase genes in a large British kindred multiply affected with Tourette's syndrome, chronic motor tics, and obsessive-compulsive behavior. (1995) (49)
- Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data (2014) (48)
- Schizophrenia susceptibility and chromosome 6p24–22 (1995) (47)
- Genetic dissection of complex traits (1996) (45)
- Genetic association of the tachykinin receptor 1 TACR1 gene in bipolar disorder, attention deficit hyperactivity disorder, and the alcohol dependence syndrome (2014) (44)
- Further tests for linkage of bipolar affective disorder to the tyrosine hydroxylase gene locus on chromosome 11p15 in a new series of multiplex British affective disorder pedigrees. (1996) (43)
- A procedure for combining two-point lod scores into a summary multipoint map. (1993) (43)
- Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2 (2005) (43)
- Assessing Optimal Neural Network Architecture for Identifying Disease‐associated Multi‐marker Genotypes using a Permutation Test, and Application to Calpain 10 Polymorphisms Associated with Diabetes (2003) (43)
- Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (43)
- Linkage disequilibrium between two highly polymorphic microsatellites. (1991) (42)
- Multimarkerhaplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder. (2000) (42)
- Linkage analysis of chromosome 22q12-13 in a United Kingdom/Icelandic sample of 23 multiplex schizophrenia families. (1995) (42)
- A rapid method for combined analysis of common and rare variants at the level of a region, gene, or pathway (2012) (42)
- A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12 (1998) (41)
- Coeliac disease: investigation of proposed causal variants in the CTLA4 gene region. (2003) (41)
- Genome scan of Tourette syndrome in a single large pedigree shows some support for linkage to regions of chromosomes 5, 10 and 13 (2004) (41)
- A Genetic Linkage Study of the D2 Dopamine Receptor Locus in Heavy Drinking and Alcoholism (1996) (40)
- Coeliac disease: follow‐up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11 (2001) (39)
- Pathway analysis of whole exome sequence data provides further support for the involvement of histone modification in the aetiology of schizophrenia (2016) (38)
- Genetic linkage analysis of the X chromosome in autism, with emphasis on the fragile X region (2005) (37)
- Chromosome 22 markers demonstrate transmission disequilibrium with schizophrenia (1995) (37)
- Fine Mapping by Genetic Association Implicates the Chromosome 1q23.3 Gene UHMK1, Encoding a Serine/Threonine Protein Kinase, as a Novel Schizophrenia Susceptibility Gene (2007) (37)
- Psychiatric morbidity in policemen and the effect of brief psychotherapeutic intervention — a pilot study (1994) (37)
- Power comparison of parametric and nonparametric linkage tests in small pedigrees. (2000) (37)
- No evidence for excess runs of homozygosity in bipolar disorder (2009) (37)
- The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder (2014) (37)
- A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia. (2007) (36)
- Failure to find linkage and increased homozygosity for the dopamine D3 receptor gene in Tourette's syndrome (1993) (34)
- Failure to confirm genetic association between schizophrenia and markers on chromosome 1q23.3 in the region of the gene encoding the regulator of G‐protein signaling 4 protein (RGS4) (2006) (34)
- A simple method for assessing the strength of evidence for association at the level of the whole gene (2008) (34)
- Failure to Confirm Allelic Association Between Markers at the CAPON Gene Locus and Schizophrenia in a British Sample (2006) (33)
- Case report: rapidly fatal bowel ischaemia on clozapine treatment (2006) (33)
- Optimal weighting scheme for affected sib‐pair analysis of sibship data (1997) (32)
- A pedigree‐based linkage study of coeliac disease: failure to replicate previous positive findings (1998) (32)
- A note on calculation of empirical P values from Monte Carlo procedure. (2003) (32)
- A novel method of two‐locus linkage analysis applied to a genome scan for late onset Alzheimer's disease (2001) (32)
- Allelic Association, DNA Resequencing and Copy Number Variation at the Metabotropic Glutamate Receptor GRM7 Gene Locus in Bipolar Disorder (2014) (32)
- No allelic association between bipolar affective disorder and the tryptophan hydroxylase gene. (1998) (31)
- Unsound Methodology in Investigating a Pseudoautosomal Locus in Schizophrenia (1990) (31)
- Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters. (2002) (31)
- A polygenic resilience score moderates the genetic risk for schizophrenia (2019) (31)
- Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis (2019) (31)
- Genetic association studies of schizophrenia using the 8p21-22 genes: prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CHRNA2) and arylamine N-acetyltransferase 1 (NAT1) (2001) (30)
- Chromosome 21 workshop. (1999) (29)
- Advances and Applications in Bioinformatics and Chemistry (29)
- Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population (2015) (28)
- Comparison of GENEHUNTER and MFLINK for analysis of COGA linkage data (1999) (28)
- Genetic association, mutation screening, and functional analysis of a Kozak sequence variant in the metabotropic glutamate receptor 3 gene in bipolar disorder. (2013) (28)
- Two microsatellite polymorphisms at the D5S39 locus. (1991) (27)
- OCTET does not demonstrate a lack of effectiveness for community treatment orders (2014) (27)
- A program for the monte carlo evaluation of significance of the extended transmission/disequilibrium test. (1999) (26)
- Mini‐review: Update on the genetics of schizophrenia (2018) (26)
- Genetic association and sequencing of the insulin‐like growth factor 1 gene in bipolar affective disorder (2011) (26)
- Linkage analysis and exclusion of regions of chromosomes 3 and 8 in Gilles de la Tourette syndrome following the identification of a balanced reciprocal translocation 46 XY, t(3: 8)(p21.3 q24.1) in a case of Tourette syndrome (1996) (26)
- Intensive cognitive behaviour therapy for chronic schizophrenia (1999) (25)
- The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations (2000) (25)
- Complement genes contribute sex-biased vulnerability in diverse disorders (2020) (25)
- Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology (2017) (24)
- Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia (2022) (24)
- Genetic linkage analysis of manic depression in Iceland. (1993) (24)
- A program to draw pedigrees using LINKAGE or LINKSYS data files (1990) (24)
- Neuroreceptor subunit genes and the genetic susceptibility to gilles de la tourette syndrome (1997) (23)
- Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia (2007) (23)
- Linkage studies in bipolar affective disorder with markers on chromosome 21. (1996) (23)
- Distribution of risk behaviour for HIV infection amongst intravenous drug users. (1988) (23)
- Segregation and linkage analysis in five manic depression pedigrees excludes the 5HT1a receptor gene (HTR1A) (1993) (23)
- Genome-wide association study identifies 30 loci associated with bipolar disorder (2019) (22)
- Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2018) (22)
- Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis (2020) (20)
- Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3 (2008) (20)
- Practical Experience of the Application of a Weighted Burden Test to Whole Exome Sequence Data for Obesity and Schizophrenia (2015) (20)
- Exclusion of linkage of schizophrenia to the gene for the dopamine D2 receptor (DRD2) and chromosome 11q translocation sites (1995) (20)
- A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk score (2018) (20)
- EXOME SEQUENCING IN BIPOLAR DISORDER REVEALS SHARED RISK GENE AKAP11 WITH SCHIZOPHRENIA (2021) (19)
- A pragmatic suggestion for dealing with results for candidate genes obtained from genome wide association studies (2007) (19)
- Clinical relevance of genome‐wide polygenic score may be less than claimed (2018) (19)
- Extended homozygosity is not usually due to cytogenetic abnormality (2007) (19)
- Linkage study of the D5 dopamine receptor gene (DRD5) in multiplex Icelandic and English schizophrenia pedigrees. (1996) (19)
- Linkage analysis of manic depression (bipolar affective disorder) in Icelandic and British kindreds using markers on the short arm of chromosome 18. (1997) (18)
- Comparison of artificial neural network analysis with other multimarker methods for detecting genetic association (2007) (18)
- Description of the Genetic Analysis Workshop 10 bipolar disorder linkage data sets (1997) (18)
- Schizophrenia following prenatal exposure to influenza epidemics between 1939 and 1960 (1992) (17)
- Identification of the Slynar gene (AY070435) and related brain expressed sequences as a candidate gene for susceptibility to affective disorders through allelic and haplotypic association with bipolar disorder on chromosome 12q24. (2006) (17)
- Variation in the DCP1 gene, encoding the angiotensin converting enzyme ACE, is not associated with increased susceptibility to Alzheimer's disease (2003) (17)
- Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia (2017) (17)
- Exome sequence analysis and follow up genotyping implicates rare ULK1 variants to be involved in susceptibility to schizophrenia (2017) (17)
- Investigation by Linkage Analysis of the XY Pseudoautosomal Region in the Genetic Susceptibility to Schizophrenia (1995) (17)
- Recent and future molecular genetic research into schizophrenia. (1989) (16)
- Estimated haplotype counts from case-control samples cannot be treated as observed counts. (2006) (15)
- Possible linkage of Tourette syndrome to markers on short arm of chromosome 3 (C3p21-14) (1990) (15)
- Multiple linear regression allows weighted burden analysis of rare coding variants in an ethnically heterogeneous population (2020) (15)
- The Marfan syndrome gene locus as a favoured locus for susceptibility to schizophrenia (1994) (15)
- Consideration of plausible genetic architectures for schizophrenia and implications for analytic approaches in the era of next generation sequencing (2013) (15)
- A linkage study of schizophrenia with DNA markers from chromosome 8p21-p22 in 25 multiplex families (1996) (15)
- Common HLA alleles, rather than rare mutants, confer susceptibility to coeliac disease (1999) (14)
- Likelihood ratio tests for linkage and linkage disequilibrium: asymptotic distribution and power. (1996) (14)
- Population stratifications can cause false positive linkage results if founders are untyped (1996) (14)
- A novel polymorphism in exon 11 of the WKL1 gene, shows no association with schizophrenia (2002) (14)
- Using a dummy quantitative variable to deal with multiple affection categories in genetic linkage analysis (1991) (14)
- Audit of psychiatric discharge summaries: completing the cycle (2004) (14)
- A quick and simple method for detecting subjects with abnormal genetic background in case-control samples. (2002) (13)
- New DNA markers with increased informativeness show diminished support for a chromosome 5q11–13 schizophrenia susceptibility locus and exclude linkage in two new cohorts of British and Icelandic families (1999) (13)
- Schizophrenia genetics moves into the light. (2016) (13)
- Tests of linkage and allelic association between markers in the 1p36 PRKCZ (Protein Kinase C Zeta) gene region and bipolar affective disorder (2012) (13)
- A quick and simple method for detecting subjects with abnormal genetic background in case‐control samples (2002) (13)
- Allelic association studies of genome wide association data can reveal errors in marker position assignments (2007) (13)
- Weighted burden analysis of exome‐sequenced late‐onset Alzheimer's cases and controls provides further evidence for a role for PSEN1 and suggests involvement of the PI3K/Akt/GSK‐3β and WNT signalling pathways (2020) (13)
- NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis (2019) (13)
- Semantic priming in schizophrenia (1998) (13)
- Investigation of the Ability of Haplotype Association and Logistic Regression to Identify Associated Susceptibility Loci (2006) (13)
- Linkage analysis between bipolar affective disorder and markers on chromosome X (1998) (13)
- Lack of evidence for close linkage of the glutamate GluR6 receptor gene with schizophrenia. (1996) (13)
- Combining the sibling disequilibrium test and transmission/disequilibrium test for multiallelic markers. (1999) (13)
- Minor differences in haplotype frequency estimates can produce very large differences in heterogeneity test statistics (2007) (12)
- A possible role for sarcosine in the management of schizophrenia (2019) (12)
- Family linkage study of the T-cell receptor genes in coeliac disease. (1999) (12)
- Test of Xq26.3–28 linkage in bipolar and unipolar affective disorder in families selected for absence of male to male transmission (1997) (12)
- Yin Yang Haplotypes Revisited – Long, Disparate Haplotypes Observed in European Populations in Regions of Increased Homozygosity (2010) (12)
- Mini‐review: Role of the PI3K/Akt pathway and tyrosine phosphatases in Alzheimer's disease susceptibility (2020) (12)
- Should all babies have their genome sequenced at birth? (2021) (12)
- Coeliac disease and Down syndrome: associations not due to genetic linkage on chromosome 21. (2000) (12)
- A cosmid clone for the 5HT1A receptor (HTR1A) reveals a TaqI RFLP that shows tight linkage to dna loci D5S6, D5S39, and D5S76. (1991) (11)
- Exclusion of linkage of schizophrenia of the gene for the glutamate GluR5 receptor (1997) (11)
- Adjacent genetic markers on chromosome 11p15.5 at or near the tyrosine hydroxylase locus that show population linkage disequilibrium with each other do not show allelic association with bipolar affective disorder (1999) (10)
- Rare variant analysis in multiply affected families, association studies and functional analysis suggest a role for the ITGΒ4 gene in schizophrenia and bipolar disorder (2018) (10)
- Assessing the Contribution Family Data Can Make to Case‐Control Studies of Rare Variants (2011) (10)
- Heterozygote expression in Grebe Chondrodysplasia (1986) (10)
- In-silico investigation of coding variants potentially affecting the functioning of the glutamatergic N-methyl-D-aspartate receptor in schizophrenia (2019) (10)
- Genetic variation in the miR‐708 gene and its binding targets in bipolar disorder (2016) (10)
- Markers typed in genome-wide analysis identify regions showing deviation from Hardy-Weinberg equilibrium (2009) (9)
- Microsatellite polymorphisms for chromosome 5 bands q11.2-q13.3. (1993) (9)
- Further Investigation of Linkage Disequilibrium SNPs and their Ability to Identify Associated Susceptibility Loci (2004) (9)
- Should ambiguous trios for the TDT be discarded? (2000) (9)
- Analysis of 200 000 exome-sequenced UK Biobank subjects illustrates the contribution of rare genetic variants to hyperlipidaemia (2021) (9)
- Approaches to the detection of recessive effects using next generation sequencing data from outbred populations (2013) (9)
- Re-analysis of Collaborative Study on the Genetics of Alcoholism pedigrees suggests the presence of loci influencing novelty-seeking near D12S391 and D17S1299 (2004) (9)
- CLUMPHAP: a simple tool for performing haplotype‐based association analysis (2008) (9)
- Perception of risk of HIV infection by injecting drug users and effects on medical clinic attendance. (1988) (9)
- Linkage analysis of idiopathic generalised epilepsy in families of probands with Juvenile Myoclonic Epilepsy and marker loci in the region of EPM 1 on chromosome 21 q: Unverricht-Lundborg disease and JME are not allelic variants. (1994) (8)
- Variants in ACE2 and TMPRSS2 Genes Are Not Major Determinants of COVID-19 Severity in UK Biobank Subjects (2021) (8)
- Weighted burden analysis of exome-sequenced late onset Alzheimer’s cases and controls provides further evidence for involvement of PSEN1 and demonstrates protective role for variants in tyrosine phosphatase genes (2019) (8)
- Coeliac disease: follow-up linkage study provides further support for existence of a susceptibility locus on chromosome 11p11. (2001) (8)
- Another procedure for the preliminary ordering of loci based on two point lod scores (1994) (8)
- Construction of an exome-wide risk score for schizophrenia based on a weighted burden test (2017) (7)
- Dysphagia Evaluation, Treatment, and Recommendations (2004) (7)
- Investigation of Recessive Effects in Schizophrenia Using Next‐Generation Exome Sequence Data (2015) (7)
- Initial genome wide parametric genetic linkage analysis of schizophrenia and schizophrenia spectrum disorders finds lod scores above 3.00 on four chromosomes at 1Q22-23, 5Q22-35, 8P21-23 and 11Q14-24. a further lod above 3.00 at 4Q21-31 was found within a single family. (1999) (7)
- Rare schizophrenia risk variants are enriched in genes shared with neurodevelopmental disorders (2016) (7)
- Analysis of 200,000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral (2020) (7)
- Common variants of NRXN1, LRP1B and RORA are associated with increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study (2017) (7)
- Analysis of rare coding variants in 200,000 exome‐sequenced subjects reveals novel genetic risk factors for type 2 diabetes (2021) (7)
- Medication patient safety incidents linked to rapid tranquillisation: one year's data from the National Reporting and Learning System (2015) (7)
- Community treatment orders in England: review of usage from national data (2018) (7)
- DIDMOAD SYNDROME - CONFIRMATION OF LINKAGE TO CHROMOSOME-4P, EVIDENCE FOR LOCUS HETEROGENEITY AND A PATIENT WITH UNIPARENTAL ISODISOMY FOR CHROMOSOME-49 (1995) (6)
- Polygenic risk score for schizophrenia is not strongly associated with the expression of specific genes or gene sets (2017) (6)
- Prenatal exposure to the 1957 influenza epidemic (1996) (6)
- Exclusion of linkage between schizophrenia and the gene encoding a neutral amino acid glutamate/aspartate transporter, SLC1A5. (1996) (6)
- Coding variants in ACE2 and TMPRSS2 are not major drivers of COVID-19 severity in UK Biobank subjects. (2020) (5)
- DOLINK ‐ a computer program to facilitate management of genetic data and analyses (1993) (5)
- Tests of linkage, allelic and genotypic association between schizophrenia and the gene for the D3 dopamine receptor, DRD3. (1998) (5)
- Assessment of Potential Clinical Role for Exome Sequencing in Schizophrenia. (2019) (5)
- Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia (2020) (5)
- A linkage study with the D5 dopamine receptor in Icelandic pedigrees with multiple cases of manic depression (1993) (5)
- Mapping loci influencing blood pressure in the Framingham pedigrees using model-free LOD score analysis of a quantitative trait (2003) (5)
- Weighted burden analysis in 200,000 exome-sequenced subjects characterises rare variant effects on risk of type 2 diabetes (2021) (5)
- Editorial: Topical ethical issues in the publication of human genetics research (2020) (5)
- No evidence for linkage of schizophrenia to DXS7 at chromosome Xp11. (1999) (5)
- A linkage study of affective disorder with DNA markers for the ABO-AK1-ORM linkage group near the dopamine beta hydroxylase gene (1994) (5)
- Concerns about the use of polygenic embryo screening for psychiatric and cognitive traits. (2022) (4)
- Linkage analysis of Norrie disease with an X-chromosomal ornithine aminotransferase locus. (1993) (4)
- The UCP2 exon8-insertion polymorphism is associated with Type 2 diabetes in south Asians (2003) (4)
- Effect of antipsychotics on stroke risk remains unproved (2008) (4)
- Analysis of 200,000 Exome-Sequenced UK Biobank Subjects Implicates Genes Involved in Increased and Decreased Risk of Hypertension (2021) (4)
- Use of siblings as controls in case‐control association studies (1998) (4)
- Pursuing parity: genetic tests for psychiatric conditions in the UK National Health Service (2019) (4)
- Chromosome markers in Tourette's syndrome (1991) (4)
- Family association studies of markers on chromosome 2q and Type 1 diabetes in subjects from South India (2000) (4)
- Evidence for genetic susceptibility to the alcohol dependence syndrome from the thiamine transporter 2 gene solute carrier SLC19A3 (2014) (3)
- The reality of sex (2021) (3)
- A transmission disequilibrium study on Catechol-O-Methyltransferase polymorphism in schizophrenia families (1996) (3)
- LD scores are associated with differences in allele frequencies between populations but LD score regression can still distinguish confounding from polygenicity (2019) (3)
- Standardized pedigree nomenclature. (1995) (3)
- Weighted Burden Analysis of Exome-Sequenced Case-Control Sample Implicates Synaptic Genes in Schizophrenia Aetiology (2018) (3)
- Cognitive therapy is no better than supportive counselling in schizophrenia (1999) (3)
- Lindage analysis in a large pedigree multiply affected with Gilles de la Tourette syndrome (1991) (3)
- Genome wide parametric genetic linkage analysis of bipolar and related unipolar affective disorders (manic depression) implicates chromosomes 1 and 12. (1999) (3)
- Estimating hospital bed numbers (1988) (3)
- Letter to the Editor: Schizophrenia does not represent the extreme of a normally distributed trait (2017) (3)
- Exclusion of the familial Mediterranean fever locus as a susceptibility region for autosomal dominant familial Hibernian fever. (1998) (3)
- Efficient strategies for genome scanning with affected sib pairs. (1998) (3)
- Positive allelic association between bipolar affective disorder and G6PD polymorphisms on chromosome Xq28. (1999) (2)
- [Cleft lip and palate in the Chilean population: association with BamH1 polymorphism of the transforming growth factor alpha (TGFA) gene]. (1993) (2)
- Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (2)
- Study of variants in genes implicated in rare familial migraine syndromes and their association with migraine in 200,000 exome‐sequenced UK Biobank participants (2022) (2)
- Exclusion of linkage between schizophrenia and the putative chromosome 3p24-p26 susceptibility locus (1996) (2)
- Genetic association and functional characterization of MCPH1 gene variation in bipolar disorder and schizophrenia (2019) (2)
- Analysis of whole genome sequenced cases and controls shows that the association of variants in TOMM40, BCAM, NECTIN2 and APOC1 with late onset Alzheimer’s disease is driven by linkage disequilibrium with APOE ε2/ε3/ε4 alleles (2021) (2)
- Association study of schizophrenia with variants in miR-137 binding sites (2017) (2)
- Weighted burden analysis of exome-sequenced late onset Alzheimer’s cases and controls provides further evidence for a role for PSEN1 and suggests involvement of the PI3K/Akt/GSK-3β and WNT signalling pathways (2019) (2)
- Linkage analysis in a large pedigree multiply affected with Gilles de la Tourette syndrome (1991) (2)
- Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (2)
- A new method of linkage analysis using LOD scores for quantitative traits supports linkage of monoamine oxidase activity to D17S250 in the Collaborative Study on the Genetics of Alcoholism pedigrees (2005) (2)
- Risk behaviours for HIV infection. (1989) (2)
- The role of the satellite clinic in reaching intravenous drug users at risk from HIV (1989) (2)
- Rare missense variants within a single gene form yin yang haplotypes (2015) (2)
- The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations. (2000) (1)
- CTLA-4 gene polymorphisms and susceptibility to coeliac disease (2001) (1)
- Defending attacks on statistics (1996) (1)
- Letter to the Editor: Association between smoking and psychosis may be mediated by maternal smoking during pregnancy (2017) (1)
- Replication and combined genetic analyses show that a non conservative amino acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar and unipolar affective disorders (2008) (1)
- Further genetic analyses of the PCM1 gene association with schizophrenia on chromosome 8p21 and tests of the G72, Dysbindin, RGS4, calcineurin, comt, frizzled 3, MRDS1, AKT1 and CAPON associations (2004) (1)
- Study of Transgender Patients: Conclusions Are Not Supported by Findings. (2020) (1)
- Evidence of allelic association of bipolar disorder with two genes P2RX7 and AY070435 6 MB apart on 12q24 (2005) (1)
- Exploration of weighting schemes based on allele frequency and annotation for weighted burden association analysis of complex phenotypes. (2021) (1)
- High prevalence and low fecundity of mental disorders may reflect recessive effects. (2013) (1)
- Genome wide linkage anlaysis supports the presence of two separate susceptibility loci on chromosome 1q32 for biopolar disorder and 1q21-22.3 for schizophrenia (2000) (1)
- Investigation into the Ability of SNP Chipsets and Microsatellites to Detect Association with a Disease Locus (2008) (1)
- Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2019) (1)
- Erratum: Schizophrenia susceptibility and chromosome 6p24-22 (1996) (1)
- A linkage study between a D3 dopamine receptor (DRD3) gene polymorphism and schizophrenia. (1997) (1)
- Haploinsufficiency of the HIRA gene may not always produce severe neurodevelopmental consequences (2021) (1)
- Identification of specific genes involved in schizophrenia aetiology – what difference does it make? (2022) (1)
- Positive allelic association of the marker D21S171 with bipolar disorder identifies TRPC7, a calcium channel protein on chromosome 21 at 21q22.3, as being a candidate gene for increasing susceptibility to bipolar and related unipolar affective disorders (2002) (1)
- Weighted burden analysis in 200 000 exome-sequenced UK Biobank subjects characterises effects of rare genetic variants on BMI (2021) (1)
- Pseudoautosomal linkage in schizophrenia (1994) (1)
- Analysis of 200 000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of developing a mood disorder resulting in psychiatric referral (2021) (1)
- A simple approach for assessing the strength of evidence for association at the level of the whole gene (2007) (1)
- A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. (2001) (1)
- Linkage and allelic association studies of the 8p schizophrenia locus. (1999) (1)
- Weighted burden analysis in 200,000 exome-sequenced subjects characterises rare variant effects on BMI (2022) (1)
- NICE recommendations for valproate treatment are unhelpful (2005) (1)
- Genetic analysis of complex disease (1995) (1)
- Confounding factors may account for the association (2010) (1)
- Patient experience – the ingredient missing from cost-effectiveness calculations (2011) (1)
- Postviral fatigue syndrome. (1992) (1)
- Thrombolysis in acute ischaemic stroke (2012) (1)
- In silico investigation of coding variants potentially affecting the functioning of the glutamatergic N-methyl-D-aspartate receptor in schizophrenia (2018) (1)
- An allelic association study of candidate genes in the chromosome 21q22.3 region implicated in bipolar affective disorder (1998) (0)
- Obituary (1914) (0)
- How to manage the first episode of schizophrenia. Innovations in service provision need evidence, not opinion. (2001) (0)
- 65 IDENTIFYING SUSCEPTIBILITY LOCI FOR TOURETTE'S SYNDROME IN A DENSELY AFFECTED PEDIGREE (2019) (0)
- A genetic association study implicates the chromosome 11q23.3 gene FXYD6 encoding phopshohippolin in susceptibility to schizophrenia in University College London and Aberdeen case control samples (2007) (0)
- Study of association of migraine susceptibility genes with common migraine in 200,000 exome-sequenced UK Biobank participants (2021) (0)
- X linkage in bipolar disorder: Allelic association studies of the Xq26-28 region implicate the G6PD locus and flanking region but not the a3 subunit of the GABA receptor gene (GABRA3) in a UK bipolar case-control sample (2002) (0)
- P.3.e.012 Potential involvement of a CLSTN3 variant in susceptibility to schizophrenia (2016) (0)
- Author's reply (2020) (0)
- A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk score (2018) (0)
- Detection of potential aetiological base pair changes causing genetic susceptibility to schizophrenia in the pericentriolar material 1 (PCM1) gene on chromosome 8p22 supports evidence from allelic association (2005) (0)
- Stamp of Approval. (1977) (0)
- Genome scan of alcoholism in multiplex British families supports the presence of susceptibility loci on chromosome 1p and 1q (2002) (0)
- F130EXOME SEQUENCE ANALYSIS IDENTIFY RARE GENETIC VARIANT IMPLICATED IN SUSCEPTIBILITY TO SCHIZOPHRENIA (2019) (0)
- Attempted confirmation of the fine mapping of a putative bipolar susceptibility locus on chromosome 4P16.1 at the PPP2R2C gene locus (2004) (0)
- Strain and stress measurement (2006) (0)
- Elastic modulus and related properties (2010) (0)
- Friction - types of (2006) (0)
- Resequencing of the TRPM2 and TSPEAR genes provides additional SNPs in the 21q22.3 region of chromosome 21 that show strengthened allelic and haploptypic association with bipolar disorder (2004) (0)
- PSEUDOAUTOSOMAL LINKAGE IN SCHIZOPHENIA. AUTHOR'S REPLY (1994) (0)
- Prion disease (1997) (0)
- PW01-232 - Connectivity Genes In Comorbid Alcoholism And Bipolar Disorder (2010) (0)
- Analysis of 50,000 exome-sequenced UK Biobank subjects fails to identify genes influencing probability of psychiatric referral (2020) (0)
- Unexplained Allele-Calling Errors May Account for Apparent Denisovan-Neanderthal F1 Genome (2018) (0)
- Clinical features of UK Biobank subjects carrying loss of function variants in genes implicated in schizophrenia pathogenesis (2022) (0)
- The Role of the IDDM Genes in the Genetic Aetiology of Coeliac Disease: A Linkage Study (1997) (0)
- Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (0)
- No linkage found between chromosome 11p15.5 markers and manic-depressive illness. (1998) (0)
- depression in the region of the dopamine (D2) receptor gene No evidence for a susceptibility locus predisposing to manic (2011) (0)
- Clinical features of UK Biobank subjects carrying protein-truncating variants in genes implicated in schizophrenia pathogenesis (2021) (0)
- Strain and stress (2006) (0)
- Fine mapping of the chromosome 1q23-24.2 schizophrenia susceptibility region near the RGS4 D1S196 and Capon loci (2004) (0)
- Do damaging variants of SLC6A9, the gene for the glycine transporter 1 (GlyT-1), protect against schizophrenia? (2019) (0)
- Gene brain structure relationships: arbitrary assumptions of heterogeneity generate unfalsifiable claims. (2007) (0)
- PW01-233 - Searching For Alcoholism Vulnerability Genes: Uk-Coga Provisional Clinical Findings (2010) (0)
- A genetic association study implicates the chromosome 11q23.3 gene FXYD6 in susceptibility to schizophrenia (2006) (0)
- Genetic linkage studies of the functional psychoses (1993) (0)
- Further tests of allelic association and transmission disequilibrium between the tyrosine hydroxylase gene locus on chromosome 11p15 with bipolar and related unipolar affective disorders in familial and case-control samples. (1997) (0)
- Universitet Low-frequency variation in TP 53 has large effects on head circumference and intracranial (2019) (0)
- Report of a total genome scan for genes increasing susceptibility to alcoholism by genetic linkage analysis in multiplex British families. (2000) (0)
- Identification of specific genes involved in schizophrenia aetiology – what difference does it make? – CORRIGENDUM (2022) (0)
- Extension of conditional model-free likelihood-based linkage analysis to additive and other models. (2002) (0)
- RE: Extending the vulnerability–stress model of mental disorders: three-dimensional NPSR1 × environment × coping interaction study in anxiety (2022) (0)
- In memoriam: Hugh Malcolm Douglas Gurling. (2014) (0)
- Genetic epidemiology of binging and vomiting. (1998) (0)
- ARE FIRST-RANK SYMPTOMS ENCRYPTION ERRORS ? AUTHOR'S REPLY (1998) (0)
- Bipolar Related Functional Variants in Calcium Channel Genes (2017) (0)
- CONNECTIVITY GENES IN COMORBID ALCOHOLISM AND BIPOLAR DISORDER (2010) (0)
- M23 GENETIC ASSOCIATION AND FUNCTIONAL CHARACTERIZATION OF A VARIANT IN THE MCPH1 GENE IN BIPOLAR DISORDER AND SCHIZOPHRENIA (2019) (0)
- Fine mapping of a new bipolar and unipolar affective disorder locus on chromosome 1p36 (2006) (0)
- Estimation of haplotypes at DRD2 may have produced misleading results. (2006) (0)
- Report of current progress in linkage analysis of manic depression in Iceland and at University College and Middlesex School of Medicine (1991) (0)
- Professor Hugh Gurling MBBS (2014) (0)
- VKučinskas-2001-2016 (2016) (0)
- Investigation of Association of Rare, Functional Genetic Variants With Heavy Drinking and Problem Drinking in Exome Sequenced UK Biobank Participants (2021) (0)
- Toughness and crack prevention (2006) (0)
- Consider factors that are important to patients when quantifying harms (2013) (0)
- Coeliac Disease and the Ctla-4/CD28 Gene Region: Evidence for Association in UK Families (2002) (0)
- Antidepressants and counselling for major depression in primary care. Counselling is not demonstrably as effective as drug treatment for depression. (2001) (0)
- C282Y mutation and type 2 diabetes. Study was much too small for inferences to be drawn. (2000) (0)
- GENETIC EPIDEMIOLOGY OF BINGING AND VOMITING. AUTHOR'S REPLY (1998) (0)
- Failure to confirm allelic association between COMT and bipolar disorder in a large UK sample (2006) (0)
- Report fails to acknowledge problems with at-home HIV test (2013) (0)
- Waking Up the Nation , One Reader at a Time . . . Finally an Answer to the Most Common Medical Complaint-Fatigue (0)
- Prion diseases. (1997) (0)
- Suspension of nurse who gave drug on consultant's instructions. Patients should be alert to doctors' willingness to use subterfuge to give drugs. (1997) (0)
- Margaret Curtis (née Fisher) (2005) (0)
- Translational research in medical education: What constitutes as evidence? (2018) (0)
- Genetic mapping of disease genes. Edited by I‐H. Pawlowitzki, J. H. Edwards and E. A. Thompson. London: Academic Press. 1997. Pp. 288. £45.00. (1998) (0)
- Link between outcome and service quality is not clear (2013) (0)
- Knowledge to practice: How health professions educators implement educational research into teaching practice (2017) (0)
- UK 10 K Consortium (2019) (0)
- Age at first birth in women is genetically associated with increased risk of schizophrenia (2018) (0)
- A microarray gene expression and genetic association study of the RGS4 gene in schizophrenia (2004) (0)
- First-aid Training (1970) (0)
- Recurrent pyoderma in a family with a defect in leucocyte locomotion (1985) (0)
- Follow-up linkage study of coeliac disease: Further evidence for the existence of a susceptibility locus on chromosome 11p11 (2001) (0)
- With Rhyme and Reason. (1975) (0)
- Systematic genome scan of alcoholism using genetic linkage analysis in multiplex British families supports the presence of susceptibility loci on chromosome 1p and 16p. (2001) (0)
- An allelic association study in a UK case-control sample testing the schizophrenia susceptibility locus on chromosome 1q21-22 (2002) (0)
- GENOMIC CLONING, LOCALIZATION AND IDENTIFICATION OF A HIGHLY POLYMOROHIC MICROSATELLITE SEQUENCE FOR THE D5-DOPAMINE NEURORECEOTOR GENE LOCUS (DRD5) ON CHROMOSOME-4P WHICH SHOWS NO LINKAGE TO SCHIZOPHRENIA, MANIC-DEPRESSION AND TOURETTE SYNDROME (1993) (0)
- Genome-wide Associated Schizophrenia Snps Do Not Predict Age-of-onset in Bipolar I Disorder (2015) (0)
- A search for the risk allele for bipolar affective disorder on chromosome 12q24.2. (2000) (0)
- Pontefract Hospitals NHS Trust: Interim evaluation of the (1997) (0)
- Linkage analysis of the beta-1 GABAA receptor subunit gene locus in the genetic susceptibility to schizophrenia in British and Icelandic families. (1997) (0)
- Psychiatry SHOs should consider psychological treatment for depression (2007) (0)
- Allelic and haplotypic association with bipolar disorder implicates a 300 kilobase region on chromosome 12q24.3 containing novel brain expressed gene sequences (2005) (0)
- 22 . 1-11 . 2 and 1 q 21 . 3-24 . 2 (2015) (0)
- Association study of rare nonsynonymous variants of FTO in bipolar disorder. (2016) (0)
- Association study between patients with bipolar disorder and markers from the candidate region on chromosome 12q24.2-12q24.3. (1999) (0)
- Corrigendum to "Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia " [131/1-2 (2020) 277-283]. (2021) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With David Curtis?
David Curtis is affiliated with the following schools: