David E. Metzler
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Biology
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Biochemistry
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Biology
Why Is David E. Metzler Influential?
(Suggest an Edit or Addition)David E. Metzler's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biochemistry: The Chemical Reactions of Living Cells (1977) (739)
- A General Mechanism for Vitamin B6-catalyzed Reactions1 (1954) (535)
- Band Shapes of the Electronic Spectra of Complex Molecules (1969) (301)
- Spectra and Ionization Constants of the Vitamin B6 Group and Related 3-Hydroxypyridine Derivatives1 (1955) (238)
- Equilibriums and absorption spectra of Schiff bases (1980) (212)
- Some Transamination Reactions Involving Vitamin B61 (1952) (198)
- Equilibria between Pyridoxal and Amino Acids and their Imines1 (1957) (172)
- Transamination of Pyridoxamine and Amino Acids with Glyoxylic Acid1 (1954) (115)
- Spectra of 3-hydroxypyridines. Band-shape analysis and evaluation of tautomeric equilibria. (1973) (114)
- The photochemical degradation of riboflavin (1963) (111)
- The Reversible Catalytic Cleavage of Hydroxyamino Acids by Pyridoxal and Metal Salts1 (1953) (107)
- The oxidation of a reduced pyridine nucleotide analog by flavins (1960) (106)
- Deamination of serine. I. Catalytic deamination of serine and cysteine by pyridoxal and metal salts. (1952) (95)
- Refinement and Comparisons of the Crystal Structures of Pig Cytosolic Aspartate Aminotransferase and Its Complex with 2-Methylaspartate* (1997) (95)
- Chemistry of the inactivation of cytosolic aspartate aminotransferase by serine O-sulfate. (1982) (92)
- A novel reaction of the coenzyme of glutamate decarboxylase with L-serine O-sulfate. (1982) (82)
- Structures of Thiamine in Basic Solution1 (1957) (81)
- PHOTOCHEMICAL DEGRADATION OF FLAVINS‐IV. STUDIES OF THE ANAEROBIC PHOTOLYSIS OF RIBOFLAVIN * (1967) (80)
- Band-shape analysis and resolution of electronic spectra of pyridoxal phosphate and other 3-hydroxypyridine-4-aldehydes. (1976) (79)
- Catalytic racemization of amino acids by pyridoxal and metal salts. (1952) (70)
- Photochemical degradation of flavins. V. Chromatographic studies of the products of photolysis of riboflavin. (1968) (67)
- ACID-CATALYZED ADDITION OF WATER TO 1,4-DIHYDRONICOTINAMIDE DERIVATIVES. (1963) (63)
- 2 Pyridoxal-Linked Elimination and Replacement Reactions (1972) (62)
- Machine computation of equilibrium constants and plotting of spectra of individual ionic species in the pyridoxal--alanine system. (1967) (62)
- [77] Analyzing spectra of vitamin B6 derivatives (1970) (61)
- Reaction of apoaspartate aminotransferase with analogs of pyridoxal phosphate. (1969) (55)
- Deamination of serine. II. D-Serine dehydrase, a vitamin B6 enzyme from Escherichia coli. (1952) (52)
- Photochemical Degradation of Flavins. II. The Mechanism of Alkaline Hydrolysis of 6,7-Dimethyl-9-formylmethylisoalloxazine1,2 (1965) (48)
- Quantitative description of absorption spectra of a pyridoxal phosphate-dependent enzyme using lognormal distribution curves. (1987) (43)
- Metal Chelates of Imines Derived from Pyridoxal and Amino Acids1 (1961) (38)
- Equilibria and absorption spectra of tryptophanase. (1991) (38)
- Preliminary crystallographic study of aspartate: 2-oxoglutarate aminotransferase from pig heart. (1977) (38)
- Photochemical degradation of flavins. VI. A new photoproduct and its use in studying the photolytic mechanism. (1971) (37)
- 2-(Hydroxymethyl) aspartic acid: synthesis, crystal structure, and reaction with a transaminase (1980) (36)
- Complexes of riboflavin with silver and other metal ions. (1961) (33)
- The Distribution of Ferric Iron between Hydrochloric Acid and Isopropyl Ether Solutions. III. Spectral, Isopiestic and Magnetic Susceptibility Studies (1950) (33)
- Crystalline enzyme.substrate complexes of asparate aminotransferase. (1978) (33)
- Pyridoxal 5'-phosphate and analogs as probes of coenzyme-protein interaction. (1979) (31)
- The Distribution of Ferric Iron between Hydrochloric Acid and Isopropyl Ether Solutions. I. The Compound Extracted and the Extraction at Constant Acid Concentration (1950) (30)
- The Widespread Applicability of Lognormal Curves for the Description of Absorption Spectra (1985) (29)
- Schiff bases and geminal diamines derived from pyridoxal 5'-phosphate and diamines (1989) (29)
- Spectroscopic studies of quinonoid species from pyridoxal 5'-phosphate. (1988) (28)
- Role of an active site residue analyzed by combination of mutagenesis and coenzyme analog. (1993) (27)
- Shapes of spectral bands of visual pigments (1978) (25)
- Correlation of polarized absorption spectroscopic and X-ray diffraction studies of crystalline cytosolic aspartate aminotransferase of pig hearts. (1988) (24)
- Photoconversion of riboflavin to lumichrome in plant tissues. (1972) (24)
- PHOTCHEMICAL DEGRADATION OF FLAVINS—III. HYDROXYETHYL AND FORMYLMETHYL ANALOGS OF RIBOFLAVIN * (1967) (23)
- NMR observation of exchangeable protons of pyridoxal phosphate and histidine residues in cytosolic aspartate aminotransferase. (1991) (23)
- Digital analysis of electronic absorption spectra (1977) (21)
- Decarboxylation of pyruvate by thiamine analogues. (1959) (20)
- Tautomerism in pyridoxal phosphate and in enzymatic catalysis. (1979) (20)
- Enzymatically active truncated cat brain glutamate decarboxylase: expression, purification, and absorption spectrum. (1994) (19)
- The catalytic decarboxylation of pyruvate by thiamine. (1959) (19)
- Reaction of pyridoxal 5'-sulfate with apoenzyme of aspartate aminotransferase. Covalent labeling of the protein with elimination of sulfate. (1974) (18)
- Schiff bases of pyridoxal 5′-phosphate with Tris and glycine (1988) (16)
- Resonance Raman spectra of the pyridoxal coenzyme in aspartate aminotransferase. Evidence for pyridine protonation and a novel photochemical H/D exchange at the imine carbon atom. (1985) (16)
- Circular dichroism of L-glutamic acid decarboxylase. (1967) (15)
- Band-shape analysis and display of fine structure in protein spectra: a new approach to perturbation spectroscopy. (1972) (15)
- Use of 1H-15N heteronuclear multiple-quantum coherence NMR spectroscopy to study the active site of aspartate aminotransferase. (1997) (15)
- The reversible inactivation of L-threonine hydratase of sheep liver by L-serine. (1968) (15)
- Convulsant activity of pyridoxal sulphate and phosphonoethyl pyridoxal: Antagonism by GABA and its synthetic analogues (1983) (15)
- Is pyridoxal 5'-phosphate an affinity label for phosphate-binding sites in proteins?: The case of bovine glutamate dehydrogenase. (1993) (15)
- Studies of 6-fluoropyridoxal and 6-fluoropyridoxamine 5'-phosphates in cytosolic aspartate aminotransferase. (1985) (15)
- NMR studies of 1H resonances in the 10-18-ppm range for cytosolic aspartate aminotransferase. (1994) (15)
- Water-Soluble Vitamins Part II (1956) (14)
- Synthesis of vitamin B6 derivatives. III. 3- (4-formyl-3-hydroxy-2-methyl-5-pyridyl)propionic acid, an analog of pyridoxal phosphate† (1967) (13)
- The Distribution of Ferric Iron between Hydrochloric Acid and Isopropyl Ether Solutions. II. Polymerization of the Iron in the Ether Phase, the Effect of the Acid Concentration on the Distribution, and the Two-Ether-Phase Region (1950) (13)
- Formation and Possible Structure of Covalent Hydrates of Alloxazines (1972) (13)
- Sulfur in proteins (1981) (12)
- A TRICYCLIC FORM OF THIAMINE (1962) (12)
- A role for pyridoxal phosphate in the control of dephosphorylation of phosphorylase a. (1979) (12)
- NMR studies of 1H resonances in the 10-18-ppm range for aspartate aminotransferase from Escherichia coli. (1994) (12)
- Properties of 4-ethenyl and 4-ethynyl analogs of pyridoxal phosphate and their reactions with the apo form of asparatate aminotransferase. (1975) (11)
- Reactions of phosphonate analogs of pyridoxal phosphate with apo-aspartate aminotransferase. (1989) (11)
- Synthesis of vitamin b6 derivatives. II. 3‐Hydroxy‐4‐hydroxymethyl‐2‐methyl‐5‐pyridine acetic acid and related substances (1966) (11)
- The pH dependence of the kinetic parameters of threonine dehydrase. (1962) (11)
- NMR spectroscopy of exchangeable protons of glucoamylase and of complexes with inhibitors in the 9-15-ppm range. (1994) (10)
- ANALOGS OF GLUTAMIC ACID : SYNTHESIS AND BIOLOGICAL EVALUATION (1990) (10)
- Reactions of 3'-O-methylpyridoxal 5'-phosphate in aspartate aminotransferase. (1987) (10)
- Conformationally defined imine derivative of pyridoxal: 7,8-dihydro-3-methyl-2,6-naphthyridine-4-ol (1969) (10)
- Interaction of a 5-trans-vinylcarboxylic acid analogue of pyridoxal 5'-phosphate with apoaspartate aminotransferase. Covalent labeling of the enzyme. (1976) (9)
- Inhibition of L-glutamic acid decarboxylase by cycloglutamates. (1971) (8)
- Modeling Inhibitors in the Active Site of Aspartate Aminotransferase a (1990) (8)
- Investigation of crystalline enzyme-substrate complexes of pyridoxal phosphate-dependent enzymes. (1979) (7)
- Additions and Corrections: Structures of Thiamine in Basic Solution. (1957) (6)
- The oxidation of ethyl 1,2-dihydro-2-naphthoate by flavins and its stimulation by light. (1970) (6)
- Synthesis of vitamin B6 derivatives I. Preparation of some isopyridoxamine derivatives from isopyridoxal (1966) (6)
- NMR spectra of exchangeable protons of pyridoxal phosphate-dependent enzymes. (1991) (6)
- Analysis of protein structure: a method of choice? (1986) (5)
- Use of Iodine Monochloride in Standardization of Permanganate Solutions with Arsenious Oxide (1944) (5)
- The Transcription of Genes (1969) (5)
- The Metabolism of Nitrogen and Amino Acids (2001) (4)
- Nuclear magnetic resonance in study of active sites of pyridoxal-dependent enzymes. (1997) (4)
- X-Ray Crystallographic, 19F-NMR and UV-Visible Spectroscopic Studies of Pig Heart Cytosolic Aspartate Aminotransferase (1987) (4)
- Phosphonate analogues of pyridoxal phosphate with shortened side chains. (1983) (4)
- Studies on the Inactivated Coenzyme in the Beta Subform of Cytosolic Aspartate Aminotransferase (1987) (4)
- Crystallographic and chemical studies on cytosolic aspartate aminotransferase. (1984) (4)
- [1] Buffer preparation☆ (1971) (4)
- Charge-transfer-to-solvent spectrum of potassium iodide and the configuration-coordinate model (1972) (3)
- Starch‐Binding Domain of Aspergillus Glucoamylase‐I: Interaction with β‐Cyclodextrin and Maltoheptaosea (1994) (3)
- 4 – How Molecules Stick Together (1977) (3)
- Specific Aspects of Lipid Metabolism (2001) (3)
- Fluorine-19, Phosphorus-31, and Proton NMR Spectroscopy of Aspartate Aminotransferase Containing 6-Fluoropyridoxal Phosphate or 6-Fluoropyridoxamine Phosphate (1991) (3)
- 8 – Coenzymes—Nature's Special Reagents (1977) (3)
- An Introduction to Metabolism (2001) (3)
- 6 – Enzymes: The Protein Catalysts of Cells (1977) (3)
- REACTIONS OF PYRIDOXAL-N-METHOCHLORIDE WITH AMINO ACIDS* (1963) (2)
- Transition Metals in Catalysis and Electron Transport (2001) (2)
- Individual Components of the Beta Subform of Cytosolic Aspartate Aminotransferase (1991) (2)
- Ribosomes and the Synthesis of Proteins (2001) (2)
- Development and application of methods for the study of free flavins in plant tissues. (1972) (2)
- 15 – Biochemical Genetics and the Synthesis of Nucleic Acids and Proteins (1977) (1)
- The Organization of Metabolism (2001) (1)
- 1 – The Scene of Action (1977) (1)
- 10 – How Oxygen Meets the Electrons with Generation of ATP, and Other Stories (1977) (1)
- Amino Acids, Peptides, and Proteins (2001) (1)
- Electron Transport, Oxidative Phosphorylation, and Hydroxylation (2001) (1)
- 9 – Organization of Metabolism: Catabolic Pathways (1977) (1)
- Covalently modified peptides isolated from aspartate aminotransferase after reaction with pyridoxal 5'-sulfate. (1982) (1)
- The Chemistry of Movement (2001) (1)
- Pyrrolopyridine derivatives from pyridoxal 5'-sulfate. (1982) (1)
- Sugars, Polysaccharides, and Glycoproteins (2001) (1)
- Using 1H-and 15N-NMR spectroscopy to observe active sites of porcine cytosolic and Escherichia coli aspartate aminotransferases (1994) (1)
- The Nucleic Acids (2001) (1)
- Polyprenyl (Isoprenoid) Compounds (2001) (1)
- Schiff Bases and Geminal Diamines Derived from Pyridoxal 5′-Phosphate and Diamines. (1989) (1)
- Metal-binding by pyridoxal derivatives and possible relationships to tryptophan metabolism. (1961) (1)
- 14 – The Metabolism of Nitrogen-Containing Compounds (1977) (1)
- 7 – The Kinds of Reactions Catalyzed by Enzymes (1977) (1)
- Metals and Enzyme Activity. (1959) (0)
- Regulation and function of pyridoxal phosphate in CNS (1981) (0)
- 2 – The Molecules from Which We Are Made (1977) (0)
- NUMERICAL ANALYSIS OF ABSORPTION SPECTRA OF BIOCHEMICAL SUBSTANCES (1978) (0)
- Biochemical Defense Mechanisms (2001) (0)
- Preface for Volume 2 (2001) (0)
- Microspectrophotometry on Crystals of Cytosolic Aspartate Aminotransferase (1991) (0)
- Vitamins and Coenzymes (2003) (0)
- The Regulation of Enzymatic Activity and Metabolism (2001) (0)
- 16 – Growth, Differentiation, and Chemical Communication between Cells (1977) (0)
- NMR studies of 6-fluoropyridoxal 5'-phosphate-containing cytosolic aspartate aminotransferase. (1984) (0)
- Coenzymes of Oxidation—Reduction Reactions (2001) (0)
- Light and Life (2001) (0)
- Growth and Development (2001) (0)
- 12 – Some Specific Pathways of Metabolism of Carbohydrates and Lipids (1977) (0)
- Determining Structures and Analyzing Cells (2001) (0)
- 1H and15N NMR Spectroscopy of Aspartate Aminotransferase and Related Schiff Bases and Tautomerism in Enzyme Active Sites (2000) (0)
- Preface for Volume 1 (2001) (0)
- 3 – Energetics of Biochemical Reactions (1977) (0)
- Organization, Replication, Transposition, and Repair of DNA (2001) (0)
- Chemical Communication Between Cells (2001) (0)
- How Macromolecules Associate (2001) (0)
- Transferring Groups by Displacement Reactions (2001) (0)
- Mathematical Induction Again (Divisibility Proof) (2011) (0)
- Enzymatic Addition, Elimination, Condensation, and Isomerization (2001) (0)
- 5 – Membranes and Cell Coats (1977) (0)
- 11 – Biosynthesis: How New Molecules Are Put Together (1977) (0)
- 13 – Light in Biology (1977) (0)
- Water-soluble vitamins. II. Vitamin B6, nicotinic acid, biotin, ascorbic acid. (1956) (0)
- Some Pathways of Carbohydrate Metabolism (2001) (0)
- PHOSPHONATE ANALOGS OF PYRIDOXAL PHOSPHATE WITH SHORTENED SIDE CHAINS (1983) (0)
- Thermodynamics and Biochemical Equilibria (2001) (0)
- Lipids, Membranes, and Cell Coats (2001) (0)
- Metabolism of Aromatic Compounds and Nucleic Acid Bases (2001) (0)
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