David Gius | Academic Influence

David Gius's AcademicInfluence.com Rankings

David Gius

Engineering

#5212

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#6457

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#1182

USA Rank

Biomedical Engineering

#795

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#807

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#53

USA Rank

engineering Degrees

David Gius

Philosophy

#10916

World Rank

#14985

Historical Rank

#2040

USA Rank

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#7823

World Rank

#9716

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#1227

USA Rank

philosophy Degrees

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Engineering
Philosophy

David Gius's Degrees

Doctorate Medicine Johns Hopkins University
PhD Biomedical Engineering Johns Hopkins University

Why Is David Gius Influential?

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According to Wikipedia, David R. Gius is an American physician-scientist the Zell Family Scholar Professor, Women's Cancer Research Program director, and Vice Chair of Translational Research at Northwestern University's Feinberg School of Medicine Department of Radiation Oncology and Pharmacology. His research focuses into the mechanistic connection between aging, cellular and/or mitochondrial metabolism, and carcinogenesis focusing on the Sirtuin gene family.

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David Gius's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA (2008) (847)
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. (2010) (806)
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. (2010) (763)
Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology (2004) (661)
Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice (2013) (512)
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. (2011) (466)
Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation. (2011) (351)
Ionizing Radiation-Induced Oxidative Stress Alters miRNA Expression (2009) (315)
Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb. (1997) (299)
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial SIRT3 (2015) (294)
Intracellular oxidation/reduction status in the regulation of transcription factors NF-kappaB and AP-1. (1999) (271)
Oxidative stress, redox, and the tumor microenvironment. (2004) (269)
Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death (2002) (259)
SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression (2008) (248)
Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity. (2004) (207)
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation. (2000) (204)
Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements (1990) (198)
SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice* (2010) (192)
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. (2004) (190)
Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing (2014) (185)
Redox signaling in cancer biology. (2006) (183)
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity. (2003) (182)
Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. (2019) (172)
SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis. (2012) (165)
Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. (2005) (162)
SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity. (2010) (158)
2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism. (2003) (151)
Regulation of MnSOD enzymatic activity by Sirt3 connects the mitochondrial acetylome signaling networks to aging and carcinogenesis. (2014) (149)
SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells. (2014) (148)
Thioredoxin reductase as a novel molecular target for cancer therapy. (2006) (148)
SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient- and exercise-induced stress. (2014) (147)
Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress (2011) (144)
Transduced p16INK4a peptides inhibit hypophosphorylation of the retinoblastoma protein and cell cycle progression prior to activation of Cdk2 complexes in late G1. (1999) (131)
The human sirtuin family: Evolutionary divergences and functions (2011) (130)
Exosomes as a Drug Delivery System in Cancer Therapy: Potential and Challenges. (2018) (120)
SIRT3 Is Crucial for Maintaining Skeletal Muscle Insulin Action and Protects Against Severe Insulin Resistance in High-Fat–Fed Mice (2015) (117)
Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation (2002) (116)
Thioredoxin Reductase as a Potential Molecular Target for Anticancer Agents That Induce Oxidative Stress (2004) (112)
Characterization of the murine SIRT3 mitochondrial localization sequence and comparison of mitochondrial enrichment and deacetylase activity of long and short SIRT3 isoforms (2010) (108)
Inhibition of nuclear factor-kappaB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma. (2005) (106)
Heat Shock Inhibits Radiation-induced Activation of NF-κB via Inhibition of I-κB Kinase* (1999) (103)
Radiosensitizing and anti-proliferative effects of resveratrol in two human cervical tumor cell lines. (2002) (98)
BAT3 and SET1A Form a Complex with CTCFL/BORIS To Modulate H3K4 Histone Dimethylation and Gene Expression (2008) (94)
G Protein-Coupled Bile Acid Receptor TGR5 Activation Inhibits Kidney Disease in Obesity and Diabetes. (2016) (93)
Sirt3, Mitochondrial ROS, Ageing, and Carcinogenesis (2011) (93)
SIRT2 is a tumor suppressor that connects aging, acetylome, cell cycle signaling, and carcinogenesis. (2012) (90)
Inducible and constitutive enhancer domains in the noncoding region of human papillomavirus type 18 (1988) (89)
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy (2021) (86)
Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy. (2017) (85)
Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariates. (2007) (84)
SIRT2 directs the replication stress response through CDK9 deacetylation (2012) (83)
SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis (2017) (83)
A novel p53‐inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis‐inducing factor (AIF) (2002) (83)
Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2 (2017) (81)
Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase. (2001) (77)
Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3-mediated activation of superoxide dismutase 2 (2017) (77)
SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth. (2016) (76)
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase. (2002) (76)
Redox-sensitive signaling factors as a novel molecular targets for cancer therapy. (2005) (75)
Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells (2011) (75)
Cell cycle-coupled variation in topoisomerase IIalpha mRNA is regulated by the 3'-untranslated region. Possible role of redox-sensitive protein binding in mRNA accumulation. (2000) (72)
CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance (2015) (70)
Dietary restriction: standing up for sirtuins. (2010) (70)
Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress. (2012) (70)
Thioredoxin and thioredoxin reductase as redox-sensitive molecular targets for cancer therapy. (2007) (69)
Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer (2013) (69)
Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer. (2014) (68)
Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress (2017) (68)
Manganese superoxide dismutase (SOD2): is there a center in the universe of mitochondrial redox signaling? (2017) (64)
Co-activation of ERK, NF-κB, and GADD45β in Response to Ionizing Radiation* (2005) (63)
Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor. (1993) (58)
ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA. (2016) (54)
SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis (2014) (54)
Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity. (2012) (53)
Activation of human papillomavirus type 18 gene expression by herpes simplex virus type 1 viral transactivators and a phorbol ester (1989) (53)
SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor Growth. (2017) (53)
Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts. (2013) (52)
Site-specific processing of Ras and Rap1 Switch I by a MARTX toxin effector domain (2015) (52)
CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region. (2008) (50)
Emerging evidence for targeting mitochondrial metabolic dysfunction in cancer therapy (2018) (48)
DNMT1 as a Molecular Target in a Multimodality-Resistant Phenotype in Tumor Cells (2008) (46)
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation. (2008) (43)
BAG-4/SODD and Associated Antiapoptotic Proteins Are Linked to Aggressiveness of Epithelial Ovarian Cancer (2007) (42)
Redox factor-1 (Ref-1) mediates the activation of AP-1 in HeLa and NIH 3T3 cells in response to heat shock. (1999) (40)
Co-activation of ERK, NF-kappaB, and GADD45beta in response to ionizing radiation. (2005) (39)
SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer (2019) (38)
Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype. (2016) (37)
Patterns of care for women with cervical cancer in the United States (2008) (36)
Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas. (2013) (36)
Redox Factor-1 (Ref-1) Mediates the Activation of AP-1 in HeLa and NIH 3T3 Cells in Response to Heat Shock* (1999) (36)
Molecular and clinical responses in a pilot study of gefitinib with paclitaxel and radiation in locally advanced head-and-neck cancer. (2010) (35)
Inhibition of Stress-Inducible Kinase Pathways by Tumorigenic Mutant p53 (2003) (35)
Genomic and phenotypic analysis reveals a key role for CCN1 (CYR61) in BAG3—modulated adhesion and invasion (2009) (34)
In vitro and In vivo Radiosensitization Induced by the Ribonucleotide Reductase Inhibitor Triapine (3-Aminopyridine-2-Carboxaldehyde-Thiosemicarbazone) (2006) (33)
Superoxide mediates acute liver injury in irradiated mice lacking sirtuin 3. (2014) (33)
Metabolic regulation of Sirtuins upon fasting and the implication for cancer (2013) (33)
SIRT 3 interacts with the daf-16 homolog FOXO 3 a in the Mitochondria , as well as increases FOXO 3 a Dependent Gene expression (2008) (33)
Heat shock inhibits radiation-induced activation of NF-kappaB via inhibition of I-kappaB kinase. (1999) (30)
SIRT2 knockout exacerbates insulin resistance in high fat-fed mice (2018) (30)
Distinct Effects of Ionizing Radiation on In vivo Murine Kidney and Brain Normal Tissue Gene Expression (2006) (29)
Increased activator protein 1 activity as well as resistance to heat-induced radiosensitization, hydrogen peroxide, and cisplatin are inhibited by indomethacin in oxidative stress-resistant cells. (2001) (29)
Heat shock and the activation of AP-1 and inhibition of NF-κB DNA-binding activity: possible role of intracellular redox status (2004) (28)
SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status (2016) (27)
Cancer of the Lung: Non–Small Cell Lung Cancer and Small Cell Lung Cancer (2014) (26)
Identification of chromosomal alterations important in the development of cervical intraepithelial neoplasia and invasive carcinoma using alignment of DNA microarray data. (2006) (26)
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter (2019) (25)
Indomethacin and ibuprofen induce Hsc70 nuclear localization and activation of the heat shock response in HeLa cells. (2004) (25)
Evidence that activation of the Egr-1 promoter by v-Raf involves serum response elements. (1992) (25)
The epigenome as a molecular marker and target (2005) (24)
Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas (2016) (23)
Indomethacin lowers the threshold thermal exposure for hyperthermic radiosensitization and heat-shock inhibition of ionizing radiation-induced activation of NF-κB (2002) (22)
The new field of epigenomics: implications for cancer and other common disease research. (2004) (22)
WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis (2014) (22)
Loss of Nrf2 promotes alveolar type 2 cell loss in irradiated, fibrotic lung. (2017) (21)
High Incidence of Oral Dysesthesias on a Trial of Gefitinib, Paclitaxel, and Concurrent External Beam Radiation for Locally Advanced Head and Neck Cancers (2008) (20)
Oxidative Stress in Cancer Biology and Therapy (2012) (20)
Redox-sensitive signaling factors and antioxidants: how tumor cells respond to ionizing radiation. (2004) (20)
An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth (2020) (19)
Sirtuin 2–mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses (2018) (19)
The Makes Caterpillars Floppy (MCF)-Like Domain of Vibrio vulnificus Induces Mitochondrion-Mediated Apoptosis (2015) (19)
Histone Deacetylase Inhibitor and Demethylating Agent Chromatin Compaction and the Radiation Response by Cancer Cells (2007) (18)
Strategies of Dose Escalation in the Treatment of Locally Advanced Non-Small Cell Lung Cancer: Image Guidance and Beyond (2014) (15)
Inhibition of Sirtuin 6 Induces Neuroblastoma Differentiation. (2018) (15)
SIRT3 Overexpression Ameliorates Asbestos-Induced Pulmonary Fibrosis, mt-DNA Damage, and Lung Fibrogenic Monocyte Recruitment (2021) (14)
Thermal stress and the disruption of redox-sensitive signalling and transcription factor activation: possible role in radiosensitization (2004) (13)
Impact of NCI Clinical Announcement upon use of chemoradiation for women with cervical cancer (2007) (13)
A unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screening (2008) (13)
Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice (2018) (10)
Transduced p 16 INK 4 a Peptides Inhibit Hypophosphorylation of the Retinoblastoma Protein and Cell Cycle Progression Prior to Activation of Cdk 2 Complexes in Late G 1 1 (2000) (9)
DNA (cytosine-5)-methyltransferase 1 as a mediator of mutant p53-determined p16(ink4A) down-regulation. (2008) (9)
Antioxidant inhibition of steady-state reactive oxygen species and cell growth in neuroblastoma. (2015) (8)
Will targeting insulin growth factor help us or hurt us?: An oncologist's perspective (2011) (8)
Cell Cycle-coupled Variation in Topoisomerase IIα mRNA Is Regulated by the 3′-Untranslated Region (2000) (7)
Rearrangement of chromatin domains in cancer and development (2000) (7)
Inhibition of cyclooxygenase‐2 with NS‐398 and the prevention of radiation‐induced transformation, micronuclei formation and clonogenic cell death in C3H 10T1/2 cells (2003) (6)
Proteasome inhibitor bortezomib & re-irradiation (rRT) with scheduled treatment break in patients (pts) with head/neck squamous carcinoma (HNSCC) (2005) (5)
The holy grail of radiation oncology: lessons learned from hyperthermia. (2003) (5)
Pilot phase I study of gefitinib (GEF) in combination with paclitaxel (PAC) and radiation therapy (RT) in patients with locally advanced head and neck squamous cell carcinoma (HNSCC) and effects on epidermal growth factor receptor (EGFR) signaling pathway (2007) (5)
Glycogen Phosphorylase: A Novel Biomarker in Doxorubicin-Induced Cardiac Injury (2018) (4)
Regulation of KLF4 by posttranslational modification circuitry in endocrine resistance. (2020) (4)
MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism (2021) (4)
Systemic application of honokiol prevents cisplatin ototoxicity without compromising its antitumor effect. (2020) (4)
Homeostatic Roles of STING in Cell Proliferation and Chromosomal Instability. (2019) (4)
Low-Dose Radiation-Induced Enhancement of Thymic Lymphomagenesis in Lck-Bax Mice is Dependent on LET and Gender (2013) (4)
Changes in gene expression in SIRT3 knockout liver cells (2015) (3)
CURRENT STATUS and RECOMMENDATIONS for the FUTURE of RESEARCH, TEACHING and TESTING in the BIOLOGICAL SCIENCES of RADIATION ONCOLOGY (2014) (3)
Treatment of nasopharyngeal cancer: raising the "Barr". (2002) (3)
Increased radiosensitization in cervical tumor cells following HSP90 inhibition with geldanamycin (2003) (2)
Abstract SY11-01: Knockout mouse models for sirtuins: Genome integrity, metabolism, and cancer (2011) (2)
The role of thioredoxin in the regulation of AP-1 DNA-binding and cytotoxicity in response to ionizing radiation ASTRO research fellowship (2000) (2)
52 TAT mediated protein transduction into cells: Examination of the phosphorylation status of the retinoblastona protein in vivo (1997) (1)
Mammalian Sirtuins, Cellular Energy Regulation, and Metabolism, and Carcinogenesis (2018) (1)
Acetylation activates an alternative function of SOD2 as a stemness factor in breast cancer (2018) (1)
Thioredoxin reductase is a novel cytoplasmic signaling factor regulating radiation-induced AP-1 DNA-binding activity and gene expression via active cysteine residues (2001) (1)
Changes in sub‐nuclear structures and functional perturbations: Implications for radiotherapy (2000) (1)
In response to Drs. Van der Zee and Hulshof; and Drs. DeWhirst and Sneed (2003) (1)
Active site cysteine residues in thioredoxin reductase regulate cell cycle progression and NF-κb activity (2001) (1)
Clinical, signaling pathway, and cellular effects of epidermal growth factor receptor (EGFR) inhibition with gefitinib in combination with paclitaxel and radiation in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN). (2006) (1)
Bortezomib with Concurrent Radiation Therapy in Head and Neck Squamous Cell Carcinoma (2004) (1)
Thioredoxin reductase as a potential molecular target in the hela cellular oxidative stress response (2003) (1)
Inhibition of tumor growth by a novel engineered chimeric toxin that cleaves activated mutant and wild-type RAS (2019) (1)
66 A SIRT3/FOXO3a/MnSOD signaling model for mitochondrial superoxide levels (2007) (1)
Accommodating for Covariates Genomic Signatures for Cervical Carcinogenesis Profiling Microdissected Epithelium and Stroma to Model (2007) (1)
Ionizing radiation alters localization and phosphorylation of caveolin-1 in glioblastoma cells and blood-brain barrier endothelium. (2004) (1)
2-Deoxy-D-Glucose-induced Cytotoxicity and Radiosensitization in Tumor Cells Is Mediated via Disruptions in Thiol Metabolism 1 (2003) (1)
Targeting of gene therapy with radiation therapy (1992) (0)
metastasis via regulating alternative splicing Cell type-restricted activity of hnRNPM promotes breast cancer Material Supplemental (2014) (0)
Ionizing Radiation-induced Apoptosis of Cerebral Microvascular Endothelium Occurs with Mitochondrial Mediated Sirtuin, p53, and Grp75 Expression (2008) (0)
Cell cycle regulation following HSP90 inhibition: implications for the radiation response (2003) (0)
SIRT2 is required for in vivo tissue‐specific and whole body insulin action in mice (2018) (0)
Lysine 68 acetylation regulates the dichotomous role of MnSOD: a protective tetrameric detoxification complex versus a monomeric oncoprotein (2018) (0)
Indomethacin induced inhibition of AP-1 DNA-binding activity inhibits resistance of H202-resistant tumor cells to the cytotoxicity of hyperthermia, H202, and cisplatin (2000) (0)
OP-JNCI210063 1285..1298 (2021) (0)
SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis (2014) (0)
Clinical Trials Referral Resource. Clinical trials in cervical cancer. (2003) (0)
Aging-related Tumor Suppressor SIRT2 Modulates Cancer Metabolism Through Regulation of Pyruvate Kinase M2 (PKM2) (2012) (0)
Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice (2018) (0)
Abstract 5005: Combined targeting of IKKα and β effectively suppresses NF-κB activation, cell survival and migration in head and neck squamous cell cancers (2011) (0)
2-Deoxy-d-Glucose is a cytotoxic and radiosensitizing agent in tumor cells (2001) (0)
Contents: proteomics 12/2008. (2008) (0)
Thioredoxin nuclear localization and interaction with Ref-1 induces AP-1 DNA-binding following IR (1999) (0)
2076 Optimal 3-D conformal treatment planning of posterior lateral supratentorial tumors (1995) (0)
Abstract #3976: The response of the microRNA let-7b to ionizing radiation may involve p53 (2009) (0)
Sirtuin 3−/−Thymocytes Demonstrate Increased Levels of Superoxide, a Diminished Radiation-Induced Adaptive Response, and Accelerated Bax-Induced Thymic Lymphoma in the C57BL/6 mice (2011) (0)
MicroRNA Expression is Altered by Ionizing Radiation: A Novel Potential Therapeutic Target (2007) (0)
Post-translational Regulation of Superoxide Dismutase as a Tumor-suppressor Effect of SIRT3 (2010) (0)
SIRT3 is a Mitochondrial Tumor Suppressor and Genetic Loss Results in a Murine Model for ER/PR-Positive Mammary Tumors Connecting Metabolism and Carcinogenesis SIRT3 is a Mitochondrial Tumor Suppressor (2012) (0)
Peek Metabolism in Mice Cycle Drives Mitochondrial Oxidative + Circadian Clock NAD (2013) (0)
Erratum: Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of γ-glutamylcysteine synthetase (Free Radical Biology and Medicine (2002) 32 (650-662) PII: S089158490200755) (2002) (0)
Thioredoxin reductase regulates cell cycle progression and mediates H2O2- induced NF-kappaB and AP-1 activation (2003) (0)
Abstract 92: Sirtuin 2 mediated-deacetylation regulates cellular iron homeostasis (2014) (0)
Abstract 1328: p53 represses microRNAs let-7a and let-7b in response to ionizing radiation (2010) (0)
The Genetics of Mitochondrial Aging and the Normal Tissue Cellular Response to Radiation (2011) (0)
The Epigenome as Molecular Target for Multi-Modality Resistant Tumor Cells (2007) (0)
Abstract CN11-03: SIRT3 is a mitochrondial tumor suppressor in breast cancer (2015) (0)
72 Heat shock inhibits radiation-induced activation of a NF-kB DNA-binding via inhibition of I-kB kinase (IKK): Possible novel mechanim of hyperthermic radiosensitization (1999) (0)
The Role of Sirtuin 3 in Hepatic Injury and Loss of Cytochrome Oxidase Following Ionizing Radiation (2011) (0)
Abstract SY20-02: The SIRT3-MnSOD-Ac axis in carcinogenesis and tumor resistance (2019) (0)
Manganese Superoxide Dismutase Acetylation and Regulation of Protein Structure in Breast Cancer Biology and Therapy (2022) (0)
An antisense RNA induces epigenetic silencing of a tumor suppressor gene (2008) (0)
Pathways by Tumorigenic Mutant p53 Inhibition of Stress-Inducible Kinase (2014) (0)
Thioredoxin reductase regulates cell cycle progression through late G1 phase (2000) (0)
Therapeutic Implications of Targeting of the Sonic Hedgehog Pathway in Non-small Cell Lung Cancer (2011) (0)
Significance of Extensive Lymphovascular Space Invasion in Breast Cancer (2016) (0)
Abstract 12425: Sirt2 Mediated-Deacetylation Regulates Cellular Iron Homeostasis (2014) (0)
Low Dose (10-100cGy) Whole Body Irradiation Increases Steady-state Levels of Superoxide in C57BL/6 Thymocytes (2010) (0)
2701 : Microarray Analysis of Differential Gene Expression in Cerebral Microvasculature of C3H Mice Following Whole Brain Radiation (2006) (0)
Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter (2019) (0)
157 Nuclear localization of cytoplasmic thioredoxin in response to ionizing radiation induces AP-1 DNA-binding via an interaction between thioredoxin and redox factor-1 (ref-1) (1999) (0)
Thioredoxin reductase regulates TNFalpha-induced NF-kappaB DNA-binding and gene expression (2000) (0)
Dysregulation of MnSOD-K68 acetylation status leads to neurological and tumor-permissive phenotypes (2018) (0)
microRNA Expression is Altered In Vivo by Ionizing Radiation and may be a Target to Prevent Fibrosis (2008) (0)
SIRT3 as a Mediator of Intracellular Superoxide Levels (2008) (0)
The role of thioredoxin reductase in the regulation of AP-1 DNA-binding activity and in the cytotoxic response to ionizing radiation (2000) (0)

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