David Goltzman
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(Suggest an Edit or Addition)David Goltzman's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults (2017) (3677)
- Common genetic determinants of vitamin D insufficiency: a genome-wide association study (2010) (1177)
- The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women (2007) (1115)
- Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture (2012) (1045)
- Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism (2009) (802)
- Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction (2001) (585)
- A Meta‐Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX (2016) (467)
- Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation (1994) (460)
- An atlas of genetic influences on osteoporosis in humans and mice (2018) (409)
- Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture (2015) (399)
- A Meta‐Analysis of the Association of Fracture Risk and Body Mass Index in Women (2014) (397)
- Calcium-independent and 1,25(OH)2D3-dependent regulation of the renin-angiotensin system in 1alpha-hydroxylase knockout mice. (2008) (396)
- Relation between fractures and mortality: results from the Canadian Multicentre Osteoporosis Study (2009) (395)
- Effect of selective serotonin reuptake inhibitors on the risk of fracture. (2007) (391)
- Inactivation of the 25-Hydroxyvitamin D 1α-Hydroxylase and Vitamin D Receptor Demonstrates Independent and Interdependent Effects of Calcium and Vitamin D on Skeletal and Mineral Homeostasis* (2004) (380)
- Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death (1995) (343)
- Primary hyperparathyroidism: review and recommendations on evaluation, diagnosis, and management. A Canadian and international consensus (2016) (337)
- Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders. (2004) (329)
- Rising rural body-mass index is the main driver of the global obesity epidemic in adults (2019) (300)
- Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications. (2004) (296)
- Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type β signaling (2001) (292)
- Interaction of calcitonin and calcitonin gene-related peptide at receptor sites in target tissues. (1985) (291)
- The Autosomal Dominant Hypophosphatemic Rickets R176Q Mutation in Fibroblast Growth Factor 23 Resists Proteolytic Cleavage and Enhances in Vivo Biological Potency* (2003) (267)
- Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34. (2005) (259)
- WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk (2012) (257)
- Haploinsufficiency of parathyroid hormone-related peptide (PTHrP) results in abnormal postnatal bone development. (1996) (243)
- Structural requirements for the growth factor activity of the amino-terminal domain of urokinase. (1992) (241)
- Parathyroid hormone is essential for normal fetal bone formation. (2002) (238)
- Peak bone mass from longitudinal data: Implications for the prevalence, pathophysiology, and diagnosis of osteoporosis (2010) (237)
- Urokinase overproduction results in increased skeletal metastasis by prostate cancer cells in vivo. (1994) (236)
- Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation (2006) (221)
- Influence of calcium and 1,25-dihydroxycholecalciferol on proliferation and proto-oncogene expression in primary cultures of bovine parathyroid cells. (1989) (218)
- Direct in vivo demonstration by radioautography of specific binding sites for calcitonin in skeletal and renal tissues of the rat (1980) (211)
- Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis. (2004) (206)
- Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. (2009) (199)
- The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone. (2003) (198)
- An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells. (1990) (179)
- Cortical and trabecular bone microarchitecture as an independent predictor of incident fracture risk in older women and men in the Bone Microarchitecture International Consortium (BoMIC): a prospective study. (2019) (179)
- Bone strength: the whole is greater than the sum of its parts. (2006) (176)
- 25-Hydroxyvitamin D in Canadian adults: biological, environmental, and behavioral correlates (2011) (175)
- Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos (2011) (171)
- The impact of incident fractures on health-related quality of life: 5 years of data from the Canadian Multicentre Osteoporosis Study (2009) (167)
- Characterization of the human parathyroid hormone-like peptide gene. Functional and evolutionary aspects. (1989) (164)
- Identification of adenylate cyclase-stimulating activity and cytochemical glucose-6-phosphate dehydrogenase-stimulating activity in extracts of tumors from patients with humoral hypercalcemia of malignancy. (1983) (162)
- Discoveries, drugs and skeletal disorders (2002) (161)
- In vivo distribution of parathyroid hormone receptors in bone: evidence that a predominant osseous target cell is not the mature osteoblast. (1988) (157)
- Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition. (2001) (157)
- Plasma FGF23 levels increase rapidly after acute kidney injury (2013) (153)
- Parathyroid hormone-like peptide in normal and neoplastic human endocrine tissues. (1990) (153)
- Calcitonin receptors in the central nervous system of the rat. (1981) (148)
- Osteoporosis-related fracture case definitions for population-based administrative data (2012) (148)
- Evidence for a humoral mechanism for enhanced osteogenesis after head injury. (1990) (142)
- Cytochemical bioassay of parathyroid hormone: characteristics of the assay and analysis of circulating hormonal forms. (1980) (141)
- Mechanisms of the development of osteoblastic metastases (1997) (139)
- Circulating concentrations of parathyroid hormone‐like peptide in malignancy and in hyperparathyroidism (1990) (139)
- Circulating concentrations of parathyroid hormone‐like peptide in malignancy and in hyperparathyroidism (1990) (139)
- The osteoporosis care gap in men with fragility fractures: the Canadian Multicentre Osteoporosis Study (2008) (138)
- Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants (2020) (138)
- Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment (2011) (134)
- Defective bone mineralization and osteopenia in young adult FGFR3-/- mice. (2003) (133)
- Bisphosphonates for treatment of osteoporosis: expected benefits, potential harms, and drug holidays. (2014) (133)
- Rat parathyroid hormone-like peptide: comparison with the human homologue and expression in malignant and normal tissue. (1989) (132)
- Enhanced growth of a human keratinocyte cell line induced by antisense RNA for parathyroid hormone-related peptide. (1992) (131)
- Change in bone mineral density as a function of age in women and men and association with the use of antiresorptive agents (2008) (129)
- Regulation of parathyroid hormone-like peptide in cultured normal human keratinocytes. Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion. (1991) (128)
- The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion. (2009) (127)
- Comparison of fracture risk prediction among individuals with reduced and normal kidney function. (2015) (125)
- Programmed cell death of chondrocytes and aberrant chondrogenesis in mice homozygous for parathyroid hormone-related peptide gene deletion. (1996) (124)
- Analysis of the requirements for parathyroid hormone action in renal membranes with the use of inhibiting analogues. (1975) (120)
- The calcium-sensing receptor in bone—mechanistic and therapeutic insights (2015) (120)
- Parathyroid hormone-related peptide is required for increased trabecular bone volume in parathyroid hormone-null mice. (2004) (118)
- Malignancy-associated hypercalcemia: evaluation with a cytochemical bioassay for parathyroid hormone. (1981) (116)
- Construction and validation of a simplified fracture risk assessment tool for Canadian women and men: results from the CaMos and Manitoba cohorts (2011) (116)
- Parathyroid hormone binding in vivo to renal, hepatic, and skeletal tissues of the rat using a radioautographic approach. (1986) (115)
- Functions of vitamin D in bone (2018) (114)
- The parathyroid hormone-like peptide gene is expressed in the normal and neoplastic human endocrine pancreas. (1989) (113)
- Abundant expression of parathyroid hormone-related protein in primary rat aortic smooth muscle cells accompanies serum-induced proliferation. (1991) (113)
- Parathyroid Hormone and Parathyroid Hormone-related Peptide Inhibit the Apical Na+/H+ Exchanger NHE-3 Isoform in Renal Cells (OK) via a Dual Signaling Cascade Involving Protein Kinase A and C (*) (1995) (112)
- Characteristics of prostate-derived growth factors for cells of the osteoblast phenotype. (1987) (112)
- Osteocrin, a Novel Bone-specific Secreted Protein That Modulates the Osteoblast Phenotype* (2003) (112)
- Parathyroid Hormone-related Peptide Stimulates Osteogenic Cell Proliferation through Protein Kinase C Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway* (2001) (111)
- Cloning of Human PEX cDNA (1998) (110)
- Characterization of the major parathyroid hormone target cell in the endosteal metaphysis of rat long bones (1990) (110)
- Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein (2008) (109)
- Physiology of the Calcium-Parathyroid Hormone-Vitamin D Axis. (2018) (105)
- Dietary patterns and incident low-trauma fractures in postmenopausal women and men aged ≥ 50 y: a population-based cohort study. (2011) (102)
- Over‐production of parathyroid hormone–related peptide results in increased osteolytic skeletal metastasis by prostate cancer cells In vivo (1999) (101)
- Vitamin D receptor as a master regulator of the c-MYC/MXD1 network (2012) (101)
- Management of corticosteroid-induced osteoporosis. (2000) (101)
- Bone formation regulates circulating concentrations of fibroblast growth factor 23. (2009) (101)
- 1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling (2019) (99)
- The Relationship Between Proton Pump Inhibitor Use and Longitudinal Change in Bone Mineral Density: A Population-Based From the Canadian Multicentre Osteoporosis Study (CaMos) (2012) (99)
- The vitamin D analogue EB 1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells. (2000) (99)
- Purification of peptides with parathyroid hormone-like bioactivity from human and rat malignancies associated with hypercalcemia. (1986) (99)
- Regulation of vitamin D metabolism in normal human pregnancy. (1983) (97)
- Rat prostate adenocarcinoma cells disseminate to bone and adhere preferentially to bone marrow-derived endothelial cells. (1992) (97)
- Antisense-mediated inhibition of parathyroid hormone-related peptide production in a keratinocyte cell line impedes differentiation. (1994) (96)
- The Transcription Factor SOX9 Regulates Cell Cycle and Differentiation Genes in Chondrocytic CFK2 Cells* (2001) (96)
- Partial rescue of the Hyp phenotype by osteoblast-targeted PHEX (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) expression. (2002) (96)
- Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo. (2013) (94)
- Benefits and safety of dietary protein for bone health—an expert consensus paper endorsed by the European Society for Clinical and Economical Aspects of Osteopororosis, Osteoarthritis, and Musculoskeletal Diseases and by the International Osteoporosis Foundation (2018) (93)
- Skeletal abnormalities in Pth-null mice are influenced by dietary calcium. (2004) (92)
- Osteolysis and cancer. (2001) (89)
- Dietary patterns in Canadian men and women ages 25 and older: relationship to demographics, body mass index, and bone mineral density (2010) (87)
- A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo. (1993) (87)
- Parathyroid-hormone-related peptide in hematologic malignancies. (1996) (87)
- Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development. (2005) (87)
- Mechanisms of vitamin D₃ metabolite repression of IgE-dependent mast cell activation. (2014) (86)
- PTH and PTHrP Effects on the Skeleton (2000) (85)
- Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways. (2001) (85)
- Defects in mesenchymal stem cell self‐renewal and cell fate determination lead to an osteopenic phenotype in Bmi‐1 null mice (2010) (85)
- Association Between Change in BMD and Fragility Fracture in Women and Men (2009) (84)
- Meta‐analysis of genome‐wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women (2013) (84)
- Calcitonin as a tumor marker. Use of the radioimmunoassay for calcitonin in the postoperative evaluation of patients with medullary thyroid carcinoma. (1974) (84)
- 1α,25‐Dihydroxyvitamin D3 Promotes Vascularization of the Chondro‐osseous Junction by Stimulating Expression of Vascular Endothelial Growth Factor and Matrix Metalloproteinase 9 (2002) (83)
- Co‐Treatment of PTH With Osteoprotegerin or Alendronate Increases Its Anabolic Effect on the Skeleton of Oophorectomized Mice (2006) (83)
- A mammalian serine/threonine kinase receptor specifically binds BMP-2 and BMP-4. (1994) (83)
- Chemical and biological properties of synthetic, sulfur-free analogues of parathyroid hormone. (1976) (83)
- Parathyroid hormone for the treatment of osteoporosis: a systematic review (2006) (83)
- Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease (2016) (82)
- Repeat Low‐Trauma Fractures Occur Frequently Among Men and Women Who Have Osteopenic BMD (2009) (81)
- Studies on the mechanisms of the skeletal anabolic action of endogenous and exogenous parathyroid hormone. (2008) (80)
- Dysregulation of parathyroid hormone-like peptide expression and secretion in a keratinocyte model of tumor progression. (1991) (80)
- Does the maternal kidney contribute to the increased circulating 1,25-dihydroxyvitamin D concentrations during pregnancy? (1988) (79)
- Impaired endochondral bone development and osteopenia in Gli2-deficient mice. (2004) (79)
- Antidepressant use and 10-year incident fracture risk: the population-based Canadian Multicentre Osteoporosis Study (CaMoS) (2014) (78)
- Repositioning of the global epicentre of non-optimal cholesterol (2020) (77)
- Influence of the amino-terminus on in vitro and in vivo biological activity of synthetic parathyroid hormone-like peptides of malignancy. (1988) (77)
- Gene-encoding parathyroid hormone-like peptide: nucleotide sequence of the rat gene and comparison with the human homologue. (1990) (76)
- PTHrP Inhibits Adipocyte Differentiation by Down-Regulating PPARγ Activity via a MAPK-Dependent Pathway. (2001) (76)
- Hydroxychloroquine treatment of hypercalcemia in a patient with sarcoidosis undergoing hemodialysis. (1987) (76)
- Parathyroid hormone-related peptide interacts with bone morphogenetic protein 2 to increase osteoblastogenesis and decrease adipogenesis in pluripotent C3H10T 1/2 mesenchymal cells. (2003) (74)
- Cell cycle regulation of menin expression. (1999) (73)
- A comparison of the in vivo biochemical responses to exogenous parathyroid hormone-(1-34) [PTH-(1-34)] and PTH-related peptide-(1-34) in man. (1992) (73)
- Vertebral Fracture Status and the World Health Organization Risk Factors for Predicting Osteoporotic Fracture Risk (2009) (73)
- Identification and Characterization of 1,25-Dihydroxyvitamin D3-responsive Repressor Sequences in the Rat Parathyroid Hormone-related Peptide Gene* (1996) (73)
- Exogenous 1,25-dihydroxyvitamin D3 exerts a skeletal anabolic effect and improves mineral ion homeostasis in mice that are homozygous for both the 1alpha-hydroxylase and parathyroid hormone null alleles. (2006) (72)
- Role of the RET proto-oncogene in sporadic hyperparathyroidism and in hyperparathyroidism of multiple endocrine neoplasia type 2. (1996) (71)
- Trends in cardiometabolic risk factors in the Americas between 1980 and 2014: a pooled analysis of population-based surveys (2019) (71)
- Mechanisms of homologous and heterologous regulation of parathyroid hormone receptors in the rat osteosarcoma cell line UMR-106. (1990) (70)
- Comparative Analysis of the Radiology of Osteoporotic Vertebral Fractures in Women and Men: Cross‐Sectional and Longitudinal Observations from the Canadian Multicentre Osteoporosis Study (CaMos) (2018) (70)
- Altered ovarian function affects skeletal homeostasis independent of the action of follicle-stimulating hormone. (2007) (70)
- Signalling by fibroblast growth factor receptor 3 and parathyroid hormone-related peptide coordinate cartilage and bone development. (2004) (70)
- Calcitonin gene-related peptide mimics calcitonin actions in brain on growth hormone release and feeding. (1985) (69)
- Defective female reproductive function in 1,25(OH)2D-deficient mice results from indirect effect mediated by extracellular calcium and/or phosphorus. (2010) (69)
- Effects of calcium and of the Vitamin D system on skeletal and calcium homeostasis: lessons from genetic models (2004) (68)
- Cell-Specific Expression of the Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Gene in Kidney from Kidney-Specific and Ubiquitous Promoters1. (1997) (68)
- Expression of FGFR3 with the G380R Achondroplasia Mutation Inhibits Proliferation and Maturation of CFK2 Chondrocytic Cells (2000) (68)
- Structurally Diverse N-terminal Peptides of Parathyroid Hormone (PTH) and PTH-related Peptide (PTHRP) Inhibit the Na+/H+ Exchanger NHE3 Isoform by Binding to the PTH/PTHRP Receptor Type I and Activating Distinct Signaling Pathways* (1996) (66)
- Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension. (2016) (65)
- Cloning and characterization of the promoter regions of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene: analysis of deoxyribonucleic acid from normal subjects and patients with pseudohypoparathyroidism type 1b. (1997) (65)
- Temporal trends and determinants of longitudinal change in 25‐hydroxyvitamin D and parathyroid hormone levels (2012) (65)
- New insights into mineral and skeletal regulation by active forms of vitamin D. (2006) (65)
- Regulation of expression of the chondrocytic phenotype in a skeletal cell line (CFK2) in vitro (1993) (63)
- The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study (2014) (63)
- Characterization of the immunochemical forms of calcitonin released by a medullary thyroid carcinoma in tissue culture. (1978) (62)
- Interactions of PTH and PTHrP with the PTH/PTHrP Receptor and with Downstream Signaling Pathways: Exceptions That Provide the Rules (1999) (62)
- Constitutive expression of parathyroid hormone‐related peptide PTHnP stimulates growth and inhibits differentiation of CFK2 chondrocytes (1996) (61)
- Regulation of parathyroid hormone-related peptide production in normal human mammary epithelial cells in vitro. (1994) (60)
- Ten-year incident osteoporosis-related fractures in the population-based Canadian Multicentre Osteoporosis Study - comparing site and age-specific risks in women and men. (2015) (60)
- Protein kinase signalling pathways involved in the up-regulation of the rat alpha1(I) collagen gene by transforming growth factor beta1 and bone morphogenetic protein 2 in osteoblastic cells. (1999) (59)
- Molecular basis of the spectrum of skeletal complications of neoplasia (2000) (59)
- Calcium and vitamin D intake and mortality: results from the Canadian Multicentre Osteoporosis Study (CaMos). (2013) (57)
- Trabecular Bone Score and Incident Fragility Fracture Risk in Adults with Reduced Kidney Function. (2016) (57)
- Frailty and Risk of Fractures in Patients With Type 2 Diabetes (2019) (56)
- Parathyroid hormone-related peptide and survival of patients with cancer and hypercalcemia. (2003) (56)
- Comparison of renal and osseous binding of parathyroid hormone and hormonal fragments. (1985) (56)
- Identification and functional characterization of a novel mutation in the calcium-sensing receptor gene in familial hypocalciuric hypercalcemia: modulation of clinical severity by vitamin D status. (2007) (56)
- 25‐Hydroxyvitamin D 1α‐Hydroxylase: Structure of the Mouse Gene, Chromosomal Assignment, and Developmental Expression (2001) (55)
- The Radiology of Osteoporotic Vertebral Fractures Revisited (2019) (55)
- Proparathyroid Hormone-related Protein Is Associated with the Chaperone Protein BiP and Undergoes Proteasome-mediated Degradation* (1998) (54)
- The LDLR deficient mouse as a model for aortic calcification and quantification by micro-computed tomography. (2011) (54)
- Effects of human prostatic mitogens on rat bone cells and fibroblasts. (1987) (53)
- Vertebral Fractures in Individuals With Type 2 Diabetes: More Than Skeletal Complications Alone (2019) (53)
- Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donation. (2012) (53)
- Regulation of parathyroid hormone-related peptide production in vitro by the rat hypercalcemic Leydig cell tumor H-500. (1993) (53)
- Induction in human osteoblastic cells (SaOS2) of the early response genes fos, jun, and myc by the amino terminal fragment (ATF) of urokinase (1997) (52)
- Fibroblast Growth Factor 23 Regulation by Systemic and Local Osteoblast-Synthesized 1,25-Dihydroxyvitamin D. (2017) (52)
- Regulation in vivo of the growth of Leydig cell tumors by antisense ribonucleic acid for parathyroid hormone-related peptide. (1995) (51)
- Fragility fractures and the osteoporosis care gap in women: the Canadian Multicentre Osteoporosis Study (2011) (51)
- Cartilage abnormalities are associated with abnormal Phex expression and with altered matrix protein and MMP-9 localization in Hyp mice. (2004) (51)
- Associations of protein intake and protein source with bone mineral density and fracture risk: A population-based cohort study (2015) (51)
- The effect of cyclooxygenase-2 inhibitors on bone mineral density: results from the Canadian Multicentre Osteoporosis Study (2006) (50)
- Induction of parathyroid hormone-related peptide by the Ras oncogene: role of Ras farnesylation inhibitors as potential therapeutic agents for hypercalcemia of malignancy. (1997) (50)
- A Compilation of Partial Sequences of Randomly Selected cDNA Clones from the Rat Incisor (1995) (49)
- Therapeutic potential of non-adherent BM-derived mesenchymal stem cells in tissue regeneration (2009) (49)
- Effects of dietary iron intake and chronic kidney disease on fibroblast growth factor 23 metabolism in wild-type and hepcidin knockout mice. (2016) (49)
- Active vitamin D deficiency mediated by extracellular calcium and phosphorus results in male infertility in young mice. (2015) (48)
- Vitamin D3 differentially regulates parathyroid hormone/parathyroid hormone-related peptide receptor expression in bone and cartilage. (1999) (48)
- Impact of Femoral Neck and Lumbar Spine BMD Discordances on FRAX Probabilities in Women: A Meta-analysis of International Cohorts (2014) (48)
- Vitamin D analogs as therapeutic agents: a clinical study update. (2004) (48)
- Selective osteoblast mitogens can be extracted from prostatic tissue (1986) (47)
- In Healthy Adults, Biological Activity of Vitamin D, as Assessed by Serum PTH, Is Largely Independent of DBP Concentrations (2014) (47)
- Comparison of the pharmacokinetics of parenteral parathyroid hormone-(1-34) [PTH-(1-34)] and PTH-related peptide-(1-34) in healthy young humans. (1995) (47)
- Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans. (1999) (47)
- Discordant disappearance of bioactive and immunoreactive parathyroid hormone after parathyroidectomy. (1984) (47)
- Changes to Osteoporosis Prevalence According to Method of Risk Assessment (2006) (47)
- On the Interpretation of Rat Carcinogenicity Studies for Human PTH(1‐34) and Human PTH(1‐84) (2008) (47)
- 1,25(OH)2D deficiency induces temporomandibular joint osteoarthritis via secretion of senescence-associated inflammatory cytokines. (2013) (46)
- 1,25‐Dihydroxyvitamin D protects against age‐related osteoporosis by a novel VDR‐Ezh2‐p16 signal axis (2019) (46)
- Parathyroid hormone-like peptide: Molecular characterization and biological properties (1989) (44)
- Pretreatment with anticatabolic agents blunts but does not eliminate the skeletal anabolic response to parathyroid hormone in oophorectomized mice. (2007) (44)
- CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders. (2016) (44)
- Abnormal neurogenesis in the dentate gyrus of adult mice lacking 1,25‐dihydroxy vitamin D3 (1,25‐(OH)2D3) (2012) (44)
- Vitamin D analogs: new therapeutic agents for the treatment of squamous cancer and its associated hypercalcemia (1995) (43)
- Early lethality in Hyp mice with targeted deletion of Pth gene. (2007) (43)
- Physiology of Parathyroid Hormone. (2018) (43)
- Recent studies on the biological action of parathyroid hormone (PTH)-related peptide (PTHrP) and PTH/PTHrP receptor in cartilage and bone. (2000) (42)
- 1, 25(OH)₂D₃ inhibits hepatocellular carcinoma development through reducing secretion of inflammatory cytokines from immunocytes. (2013) (42)
- Regulation of Calcium and Magnesium (2013) (42)
- Changes in body mass index in Canadians over a five-year period: Results of a prospective, population-based study (2007) (42)
- Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice (2010) (41)
- Adrenocorticotropin and calcitonin in medullary thyroid carcinoma: frequency of occurrence and localization in the same cell type by immunocytochemistry. (1979) (41)
- Brain receptors for blood-borne calcitonin in rats: circumventricular localization and vasopressin-resistant deficiency in hereditary diabetes insipidus. (1982) (41)
- Metabolism and biological activity of parathyroid hormone in renal cortical membranes. (1976) (41)
- Isolation and analysis of human parathyrin in parathyroid tissue and plasma. Use of reversed-phase liquid chromatography. (1981) (41)
- Recombinant human parathyroid hormone synthesized in Escherichia coli. Purification and characterization. (1988) (41)
- Assessment of gene‐by‐sex interaction effect on bone mineral density (2012) (41)
- Distinctive anabolic roles of 1,25-dihydroxyvitamin D(3) and parathyroid hormone in teeth and mandible versus long bones. (2009) (40)
- Cell-specific expression of the parathyroid hormone (PTH)/PTH-related peptide receptor gene in kidney from kidney-specific and ubiquitous promoters. (1997) (40)
- Effectiveness of antiresorptive agents in the prevention of recurrent hip fractures (2007) (40)
- 1,25‐Dihydroxy vitamin D prevents tumorigenesis by inhibiting oxidative stress and inducing tumor cellular senescence in mice (2018) (40)
- Densitometer-Specific Differences in the Correlation Between Body Mass Index and Lumbar Spine Trabecular Bone Score. (2017) (40)
- Vitamin D action (2010) (39)
- Heterogeneous intracellular free calcium responses to parathyroid hormone correlate with morphology and receptor distribution in osteogenic sarcoma cells. (1992) (39)
- Population‐Wide Impact of Non‐Hip Non‐Vertebral Fractures on Mortality (2017) (39)
- Exogenous PTH‐Related Protein and PTH Improve Mineral and Skeletal Status in 25‐Hydroxyvitamin D‐1α‐Hydroxylase and PTH Double Knockout Mice (2005) (38)
- Health-related Quality of Life in Canadian Adolescents and Young Adults: Normative Data Using the SF-36 (2009) (38)
- Developmental upregulation of human parathyroid hormone (PTH)/PTH-related peptide receptor gene expression from conserved and human-specific promoters. (1998) (38)
- Examination of interspecies differences in renal and skeletal receptor binding and adenylate cyclase stimulation with human calcitonin. (1980) (38)
- Influence of guanyl nucleotides on parathyroid hormone-stimulated adenylyl cyclase activity in renal cortical membranes. (1978) (38)
- Inhibition of processing of parathyroid hormone‐related peptide by anti‐sense furin: Effect in vitro and in vivo on rat leydig (H‐500) tumor cells (1995) (38)
- Isolation and characterization of multiple isoforms of the rat urokinase receptor in osteoblasts (1994) (38)
- Identification and functional characterization of adenylate cyclase-linked receptors for parathyroid hormone-like peptides on immortalized human keratinocytes. (1992) (37)
- Bioactivity of parathyroid hormone and parathyroid hormone-like peptide: agonist and antagonist activities of amino-terminal fragments as assessed by the cytochemical bioassay and in situ biochemistry. (1991) (37)
- Role of Activator Protein 1 Transcriptional Activity in the Regulation of Gene Expression by Transforming Growth Factor β1 and Bone Morphogenetic Protein 2 in ROS 17/2.8 Osteoblast‐like Cells (2000) (37)
- Parathyroid hormone-related peptide. (1993) (37)
- Reversal of hypercalcemia with the vitamin D analogue EB1089 in a human model of squamous cancer. (1999) (37)
- Identification of an Epigenetic Signature of Osteoporosis in Blood DNA of Postmenopausal Women (2018) (37)
- Tissue-specific targeting of the pthrp gene: the generation of mice with floxed alleles. (2001) (37)
- LRP5, serotonin, and bone: Complexity, contradictions, and conundrums (2011) (37)
- Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype. (2009) (37)
- The Calcium-Sensing Receptor Mediates Bone Turnover Induced by Dietary Calcium and Parathyroid Hormone in Neonates (2010) (36)
- Association between AAAG repeat polymorphism in the P3 promoter of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene and adult height, urinary pyridinoline excretion, and promoter activity. (2002) (36)
- Proton pump inhibitors: balancing the benefits and potential fracture risks (2008) (35)
- National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries (2019) (35)
- Spine-hip T-score difference predicts major osteoporotic fracture risk independent of FRAX(®): a population-based report from CAMOS. (2011) (34)
- A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus (2013) (34)
- The calcium‐sensing receptor and 25‐hydroxyvitamin D–1α‐hydroxylase interact to modulate skeletal growth and bone turnover (2010) (33)
- Characteristics of hyperparathyroid states in the Canadian multicentre osteoporosis study (CaMos) and relationship to skeletal markers (2015) (33)
- PARATHYROID HORMONE STIMULATES MAMMALIAN RENAL 25-HYDROXYVITAMIN D3-1α-HYDROXYLASE IN VITRO (1982) (33)
- Fracture risk prediction: importance of age, BMD and spine fracture status (2013) (33)
- The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice. (2012) (33)
- Fracture risk prediction: importance of age, BMD and spine fracture status (2013) (33)
- Common genetic determinants of vitamin D insufficiency (2011) (32)
- Parathyroid Hormone and Parathyroid Hormone-related Peptide Activate the Na+/H+ Exchanger NHE-1 Isoform in Osteoblastic Cells (UMR-106) via a cAMP-dependent Pathway (*) (1995) (32)
- Teriparatide and bone turnover and formation in a hemodialysis patient with low-turnover bone disease: a case report. (2015) (32)
- Effects of passive immunization against parathyroid hormone (PTH)-like peptide and PTH in hypercalcemic tumor-bearing rats and normocalcemic controls. (1990) (32)
- The full-length calcium-sensing receptor dampens the calcemic response to 1alpha,25(OH)2 vitamin D3 in vivo independently of parathyroid hormone. (2009) (32)
- Preproparathyroid Hormone-related Protein, a Secreted Peptide, Is a Substrate for the Ubiquitin Proteolytic System* (1997) (32)
- Regulation of parathyroid hormone-related peptide by estradiol: effect on tumor growth and metastasis in vitro and in vivo. (2005) (32)
- Longitudinal changes in calcium and vitamin D intakes and relationship to bone mineral density in a prospective population-based study: the Canadian Multicentre Osteoporosis Study (CaMos). (2013) (31)
- Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight (2020) (30)
- Androgen regulation of parathyroid hormone-related peptide production in human prostate cancer cells. (2003) (30)
- Role of mitogen-activated protein kinases in the induction of parathyroid hormone-related peptide. (2000) (30)
- The Role of Parathyroid Hormone-Related Protein (PTHrP) in Osteoblast Response to Microgravity: Mechanistic Implications for Osteoporosis Development (2016) (30)
- Mechanisms of tumor metastasis to bone. (2000) (30)
- Effect of protein and steroidal osteotropic agents on differentiation and epidermal growth factor‐mediated growth of the CFK1 osseous cell line (1992) (30)
- PTHrP inhibits adipocyte differentiation by down-regulating PPAR gamma activity via a MAPK-dependent pathway. (2001) (29)
- Vitamin D and its receptor during late development. (2015) (29)
- Biochemical and morphological characterization of parathyroid hormone receptor binding to the rat osteosarcoma cell line UMR-106. (1990) (29)
- Predictors of imminent non-vertebral fracture in elderly women with osteoporosis, low bone mass, or a history of fracture, based on data from the population-based Canadian Multicentre Osteoporosis Study (CaMos) (2019) (29)
- The association between sclerostin and incident type 2 diabetes risk: a cohort study (2017) (28)
- Amplification of the parathyroid hormone-related peptide gene in a colonic carcinoma. (1996) (28)
- Using the same bone density reference database for men and women provides a simpler estimation of fracture risk (2010) (28)
- Effect of Anticholinergic Medications on Falls, Fracture Risk, and Bone Mineral Density Over a 10-Year Period (2014) (28)
- Establishment of an osseous cell line from fetal rat calvaria using an immunocytolytic method of cell selection: Characterization of the cell line and of derived clones (1990) (28)
- Examination of the requirement for metabolism of parathyroid hormone in skeletal tissue before biological action. (1978) (28)
- Specific receptors for calcitonin in the subfornical organ of the brain. (1984) (27)
- Examination of circulating parathyroid hormone in pseudohypoparathyroidism. (1985) (27)
- The Abnormal Phenotypes of Cartilage and Bone in Calcium-Sensing Receptor Deficient Mice Are Dependent on the Actions of Calcium, Phosphorus, and PTH (2011) (27)
- Biosynthesis and processing of endogenous parathyroid hormone related peptide (PTHRP) by rat Leydig cell tumor H-500. (1993) (27)
- Vascular Calcification Induced by Chronic Kidney Disease Is Mediated by an Increase of 1α‐Hydroxylase Expression in Vascular Smooth Muscle Cells (2016) (26)
- Parathyroid hormone desensitization in renal membranes of vitamin D-deficient rats is associated with a postreceptor defect. (1988) (26)
- Endogenous PTH Deficiency Impairs Fracture Healing and Impedes the Fracture-Healing Efficacy of Exogenous PTH(1-34) (2011) (26)
- Ubiquitin ligase RNF146 coordinates bone dynamics and energy metabolism (2017) (26)
- Electron and immunoelectron microscopic study of thyroidal medullary carcinoma (1978) (26)
- Synthesis and characterization of extended and deleted recombinant analogues of parathyroid hormone-(1-84): correlation of peptide structure with function. (1990) (26)
- FAM210A is a novel determinant of bone and muscle structure and strength (2018) (26)
- Absence of detectable calcitonin synthesis in the pituitary using cloned complementary deoxyribonucleic acid probes. (1982) (26)
- Geographic variation of bone mineral density and selected risk factors for prediction of incident fracture among Canadians 50 and older. (2008) (26)
- Expression and action of parathyroid hormone-related peptide in human cervical epithelial cells. (1996) (25)
- Do cyclooxygenase-2 knockout mice have primary hyperparathyroidism? (2005) (25)
- Phosphorylation of parathyroid hormone by human and bovine parathyroid glands. (1984) (25)
- Processing of pro-PTHRP by the prohormone convertase, furin: effect on biological activity. (1995) (25)
- Characterization of the rabbit renal receptor for native parathyroid hormone employing a radioligand purified by reversed-phase liquid chromatography. (1982) (25)
- Osteoporotic fractures and obesity affect frailty progression: a longitudinal analysis of the Canadian multicentre osteoporosis study (2018) (25)
- Ihh enhances differentiation of CFK-2 chondrocytic cells and antagonizes PTHrP-mediated activation of PKA. (2002) (24)
- Approach to Hypercalcemia (2016) (24)
- Evolution of Our Understanding of the Hyperparathyroid Syndromes: A Historical Perspective (2018) (24)
- Administration of exogenous 1,25(OH)2D3 normalizes overactivation of the central renin-angiotensin system in 1α(OH)ase knockout mice (2015) (23)
- Expression and regulation of parathyroid hormone-related peptide in normal and malignant melanocytes. (2000) (23)
- Meta-analysis of genome-wide studies identifies MEF2C SNPs associated with bone mineral density at forearm (2013) (23)
- Expression of parathyroid hormone-related peptide (PTHrP) and PTH/PTHrP receptor in newborn human calvaria osteoblastic cells. (1997) (23)
- Messenger ribonucleic acid from tumors associated with humoral hypercalcemia of malignancy directs the synthesis of a secretory parathyroid hormone-like peptide. (1985) (23)
- 1Alpha,25-dihydroxyvitamin D3 promotes vascularization of the chondro-osseous junction by stimulating expression of vascular endothelial growth factor and matrix metalloproteinase 9. (2002) (23)
- Total parathyroidectomy: parathyroid hormone levels and supernumerary glands in hemodialysis patients. (1984) (23)
- TIP39/parathyroid hormone type 2 receptor signaling is a potent inhibitor of chondrocyte proliferation and differentiation. (2009) (23)
- Parathyroid hormone contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium. (2009) (22)
- Mortality risk reduction differs according to bisphosphonate class: a 15-year observational study (2019) (22)
- Impaired Transforming Growth Factor-β (TGF-β) Transcriptional Activity and Cell Proliferation Control of a Menin In-frame Deletion Mutant Associated with Multiple Endocrine Neoplasia Type 1 (MEN1)* (2012) (21)
- Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification. (2019) (21)
- RETRACTED ARTICLE: Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study (2009) (21)
- Incident Fragility Fractures Have a Long‐Term Negative Impact on Health‐Related Quality of Life of Older People: The Canadian Multicentre Osteoporosis Study (2019) (21)
- The Aging Skeleton. (2019) (21)
- Cellular and molecular mechanisms of abnormal calcification following ischemia–reperfusion injury in human liver transplantation (2007) (21)
- Conversion of proparathyroid hormone to parathyroid hormone: studies in vitro with trypsin. (1976) (21)
- Tumor-associated macrophages induce the expression of FOXQ1 to promote epithelial-mesenchymal transition and metastasis in gastric cancer cells (2017) (21)
- Reduced Bone Loss Is Associated With Reduced Mortality Risk in Subjects Exposed to Nitrogen Bisphosphonates: A Mediation Analysis (2019) (21)
- Up‐regulation of Wnt‐1 and β‐catenin production in patients with advanced metastatic prostate carcinoma (2004) (20)
- Biochemical and morphological analysis of the interaction of epidermal growth factor and parathyroid hormone with UMR 106 osteosarcoma cells. (1991) (20)
- Induction of hypocalcemia by intracerebroventricular injection of calcitonin: evidence for control of blood calcium by the nervous system (1987) (20)
- Predicting fracture using 2D finite element modelling. (2012) (20)
- Calcium Sensing Receptor Absence Delays Postnatal Brain Development via Direct and Indirect Mechanisms (2013) (20)
- ras Activation of human prostate epithelial cells induces overexpression of parathyroid hormone-related peptide. (1997) (20)
- Screening for multiple endocrine neoplasia type 2A with DNA-polymorphism analysis. (1992) (20)
- A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism (2014) (19)
- In vivo demonstration of receptors in rat liver to the amino-terminal region of parathyroid hormone. (1981) (19)
- Increased PTHRP production by a tyrosine kinase oncogene, Tpr-Met: role of the Ras signaling pathway. (1996) (19)
- CaSR-mediated interactions between calcium and magnesium homeostasis in mice. (2013) (19)
- Calcium homeostasis and skeletal integrity in individuals with familial hypercholesterolemia and aortic calcification. (2010) (19)
- Exogenous PTH and Endogenous 1,25‐Dihydroxyvitamin D Are Complementary in Inducing an Anabolic Effect on Bone (2008) (19)
- Parathyroid hormone‐like peptide in normal and neoplastic mesothelial cells (1990) (19)
- Characteristics of secondary hyperparathyroidism in vitamin D-deficient dogs. (1989) (18)
- Immunohistologig study of thyroidal medullary carcinoma and pancreatic insulinoma (1977) (18)
- Parity and lactation are not associated with incident fragility fractures or radiographic vertebral fractures over 16 years of follow-up: Canadian Multicentre Osteoporosis Study (CaMos) (2019) (18)
- Studies of the effects of 1,25-dihydroxyvitamin D on skeletal and calcium homeostasis and on inhibition of tumor cell growth (2001) (18)
- Studies of the multiple molecular forms of bioactive parathyroid hormone and parathyroid hormone-like substances. (1986) (18)
- Absence of PTHrP Nuclear Localization and Carboxyl Terminus Sequences Leads to Abnormal Brain Development and Function (2012) (17)
- Dietary patterns in men and women are simultaneously determinants of altered glucose metabolism and bone metabolism. (2016) (17)
- Metabolism and biological activity of proparathyroid hormone and synthetic analogues in renal cortical membranes. (1975) (17)
- Basal bone phenotype and increased anabolic responses to intermittent parathyroid hormone in healthy male COX-2 knockout mice. (2010) (17)
- Longitudinal assessment of health-related quality of life in osteoporosis: data from the population-based Canadian Multicentre Osteoporosis Study (2019) (17)
- Kenny syndrome: description of additional abnormalities and molecular studies (1988) (16)
- The effects of antifracture therapies on the components of bone strength: assessment of fracture risk today and in the future. (2006) (16)
- Androgens Attenuate Vitamin D Production Induced by UVB Irradiation of the Skin of Male Mice by an Enzymatic Mechanism. (2015) (16)
- The p27 Pathway Modulates the Regulation of Skeletal Growth and Osteoblastic Bone Formation by Parathyroid Hormone–Related Peptide (2015) (16)
- Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment (2016) (15)
- Comparison of active vitamin D compounds and a calcimimetic in mineral homeostasis. (2010) (15)
- Correction: Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study (2016) (15)
- Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency. (2021) (15)
- 1,25-Dihydroxyvitamin D insufficiency accelerates age-related bone loss by increasing oxidative stress and cell senescence. (2020) (14)
- Defective postnatal endochondral bone development by chondrocyte-specific targeted expression of parathyroid hormone type 2 receptor. (2012) (14)
- Nonparathyroid Hypercalcemia. (2018) (14)
- Dissection of differentially regulated (G+C)-rich promoters of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene. (2000) (14)
- 1,25-Dihydroxyvitamin D₃ contributes to regulating mammary calcium transport and modulates neonatal skeletal growth and turnover cooperatively with calcium. (2011) (14)
- Bone marrow ablation demonstrates that excess endogenous parathyroid hormone plays distinct roles in trabecular and cortical bone. (2012) (14)
- The Polycomb Protein Bmi1 Plays a Crucial Role in the Prevention of 1,25(OH)2D Deficiency‐Induced Bone Loss (2019) (14)
- Gene for parathyroid hormone-like peptide is on mouse chromosome 6. (1990) (14)
- PTHrP Nuclear Localization and Carboxyl Terminus Sequences Modulate Dental and Mandibular Development in Part via the Action of p27. (2016) (13)
- Hypophosphatemia-mediated hypotension in transgenic mice overexpressing human FGF-23. (2009) (13)
- Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis. (2015) (13)
- 1,25‐dihydroxyvitamin D deficiency accelerates alveolar bone loss independent of aging and extracellular calcium and phosphorus (2018) (13)
- An Efficient Paradigm for Genetic Epidemiology Cohort Creation (2010) (12)
- Vertebral Fractures and Morphometric Deformities (2018) (12)
- Fibroblast growth factor 23 overexpression impacts negatively on dentin mineralization and dentinogenesis in mice (2011) (12)
- Differences in fracture prevalence and in bone mineral density between Chinese and White Canadians: the Canadian Multicentre Osteoporosis Study (CaMos) (2020) (12)
- Developmental and tissue-specific regulation of parathyroid hormone (PTH)/PTH-related peptide receptor gene expression. (2000) (11)
- Bioactive parathyroid hormone in canine progressive renal insufficiency. (1984) (11)
- Molecular characterization of an intragenic minisatellite (VNTR) polymorphism in the human parathyroid hormone-related peptide gene in chromosome region 12p12.1-p11.2. (1993) (11)
- Prospectively measured 10-year changes in health-related quality of life and comparison with cross-sectional estimates in a population-based cohort of adult women and men (2014) (11)
- DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide (2018) (11)
- Severe hypercalcemia associated with hydrochlorothiazide and calcium carbonate therapy. (1979) (11)
- Normative bone mineral density z-scores for Canadians aged 16 to 24 years: the Canadian Multicenter Osteoporosis Study. (2010) (11)
- Gene expression of epimorphin in rat incisor ameloblasts. (1995) (11)
- Use of genetically modified mice to examine the skeletal anabolic activity of vitamin D (2007) (11)
- Endogenous parathyroid hormone–related protein compensates for the absence of parathyroid hormone in promoting bone accrual in vivo in a model of bone marrow ablation (2013) (11)
- Emerging roles for calcium-regulating hormones beyond osteolysis (2010) (11)
- The PTH/Vitamin D/FGF23 Axis (2015) (10)
- Effectiveness of antiresorptives for the prevention of nonvertebral low-trauma fractures in a population-based cohort of women (2009) (10)
- Regulation of Calcium Homeostasis (2018) (10)
- SIRT1/FOXO3a axis plays an important role in the prevention of mandibular bone loss induced by 1,25(OH)2D deficiency (2020) (10)
- Endocrine aryl hydrocarbon receptor signaling is induced by moderate cutaneous exposure to ultraviolet light (2018) (10)
- Role of 5'-guanylylimidodiphosphate in the activation of adenylyl cyclase by parathyroid hormone. (1976) (9)
- Medullary carcinoma of the human thyroid in monolayer culture. Morphological and cytochemical correlations (1977) (9)
- An Atlas of Human and Murine Genetic Influences on Osteoporosis (2018) (9)
- Choice of lumbar spine bone density reference database for fracture prediction in men and women: a population-based analysis. (2014) (9)
- Immunoreactive parathyroid hormone-related protein: its association with preterm labor. (1995) (9)
- Inferences from genetically modified mouse models on the skeletal actions of vitamin D (2015) (9)
- Does calcitriol have actions independent from the vitamin D receptor in maintaining skeletal and mineral homeostasis? (2005) (9)
- A Risk Assessment Tool for Predicting Fragility Fractures and Mortality in the Elderly (2020) (8)
- Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan (2022) (8)
- Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk (2021) (8)
- Calcitonin receptor binding as a marker of osteoclast heterogeneity in osteopetrotic rodents (1986) (8)
- Cognitive decline is associated with an accelerated rate of bone loss and increased fracture risk in women: a prospective study from the Canadian Multicentre Osteoporosis Study (2021) (8)
- Variable number of tandem repeats polymorphism in parathyroid hormone-related protein as predictor of peak bone mass in young healthy Finnish males. (2008) (8)
- Gene for parathyroid hormone-like peptide is on rat chromosome 2. (1988) (8)
- Studies on the pathogenesis of osteoblastic metastases by prostate cancer. (1992) (8)
- A Meta-Analysis Of Trabecular Bone Score In Fracture Risk Prediction And Its Interaction With Frax (2015) (7)
- Chapter 21. Regulation of Calcium and Magnesium (2009) (7)
- Methylation patterns of human parathyroid hormone (PTH)/PTH-related peptide receptor gene promoters are established several weeks prior to onset of their function. (2000) (7)
- Determining whether women with osteopenic bone mineral density have low, moderate, or high clinical fracture risk (2010) (7)
- Salmon stanniocalcin and bovine parathyroid hormone have dissimilar actions on mammalian bone (1991) (6)
- Urokinase and the mechanism of osteoblastic metastases by prostate cancer (1992) (6)
- Vertebral Fractures: Which Radiological Criteria Are Better Associated With the Clinical Course of Osteoporosis? (2020) (6)
- Parathyroid hormone-related peptide and hypercalcemia of malignancy. (1997) (6)
- The biologic action of parathyroid hormone-related Peptide on bone and cartilage cells. (1996) (6)
- Parathyroid hormone stimulates mammalian renal 25-hydroxyvitamin D3-1 alpha-hydroxylase in vitro. (1982) (5)
- A 51-item calcium-focused food frequency questionnaire is a reliable tool to assess dietary calcium intake in postmenopausal women. (2017) (5)
- Effects of the Administration of 25(OH) Vitamin D3 in an Experimental Model of Chronic Kidney Disease in Animals Null for 1-Alpha-Hydroxylase (2017) (5)
- Parathyroid hormone and hyperparathyroidism: current concepts. (1978) (5)
- Bone mineral acquisition during childhood and adolescence: physical exercise as a preventative measure (2000) (5)
- Systemic Factors in Skeletal Manifestations of Malignancy (2002) (5)
- The Cytochemical Bioassay for Parathyroid Hormone (1983) (5)
- Bone microarchitecture, density, and geometry predict incident fracture independently of DXA BMD in older women and men: The Bone Microarchitecture International Consortium (BoMIC) (2017) (4)
- Expression and characterization of recombinant rat parathyroid hormone-related peptide (1–141) and an amino-terminally-truncated analogue (38–141) (1997) (4)
- Extending preclinical models of skeletal manifestations of malignancy to the clinical setting. (2001) (4)
- Endogenous Parathyroid Hormone–Related Protein Compensates for the Absence of Parathyroid Hormone in Promoting Bone Accrual In Vivo in a Model of Bone Marrow Ablation (2018) (4)
- Analysis of the P3 promoter of the human parathyroid hormone (PTH)/PTH-related peptide receptor gene in pseudohypoparathyroidism type 1b. (2001) (4)
- Do calcimimetics directly alter bone remodeling? (2010) (4)
- Expression of adenylate cyclase-coupled osseous parathyroid hormone and parathyroid hormone-like peptide receptors in Xenopus oocytes. (1991) (4)
- Transplantation of bone marrow-derived mesenchymal stem cells rescues partially rachitic phenotypes induced by 1,25-Dihydroxyvitamin D deficiency in mice. (2016) (4)
- Hormonal derangements in uremia (1980) (4)
- Pathophysiology of Hypercalcemia. (2021) (3)
- Modulators of Fam210a and Roles of Fam210a in the Function of Myoblasts (2020) (3)
- Novel Glial Cells Missing-2 (GCM2) variants in parathyroid disorders (2022) (3)
- Ubiquitin ligase RNF 146 coordinates bone dynamics and energy metabolism (3)
- Bone and Calcium Metabolism (2015) (3)
- A Sonic Hedgehog-Gli-Bmi1 signaling pathway plays a critical role in p27 deficiency induced bone anabolism (2022) (3)
- Retraction to: Nitrate use and changes in bone mineral density: the Canadian Multicentre Osteoporosis Study (2009) (3)
- Feasibility of a clinical trial to assess the effect of dietary calcium v. supplemental calcium on vascular and bone markers in healthy postmenopausal women (2016) (3)
- Deficiency of the parathyroid hormone‐related peptide nuclear localization and carboxyl terminal sequences leads to premature skin ageing partially mediated by the upregulation of p27 (2015) (3)
- The Osteoporosis Primer: List of contributors (2000) (3)
- THE HYPOTHALMIC MEDIAN EMINENCE OF THE HOMOZYGOUS BRATTLEBORO RAT IS DEFICIENT IN CALCITONIN‐SPECIFIC BINDING SITES * (1982) (2)
- Mechanisms of action of vitamin D in delaying aging and preventing disease by inhibiting oxidative stress. (2023) (2)
- Parathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium‐sensing receptor gene deletion (2013) (2)
- Vitamin D 3 differentially regulates parathyroid hormone / parathyroid hormone-related peptide receptor expression in bone and cartilage (1999) (2)
- Physiologic Actions of PTH I (2015) (2)
- Familial hypocalciuric hypercalcemia in an index male: grey zones of the differential diagnosis from primary hyperparathyroidism in a 13-year clinical follow up. (2020) (2)
- Identification of an Epigenetic Signature of Osteoporosis in Blood DNA of Postmenopausal Women (2021) (2)
- Combining Frailty and Trabecular Bone Score Did Not Improve Predictive Accuracy in Risk of Major Osteoporotic Fractures (2020) (2)
- Understanding Vitamin D From Mouse Knockout Models (2018) (2)
- Parathyroid hormone-related peptide and other mediators of skeletal manifestations of malignancy (2020) (2)
- Vertebral Fractures: Which Radiological Criteria Are Better Associated With the Clinical Course of Osteoporosis? (2020) (2)
- CHAPTER 43 – Target Genes: PTHrP (2005) (2)
- The three common polymorphisms p.A986S, p.R990G and p.Q1011E in the calcium sensing receptor (CASR) are not associated with chronic pancreatitis. (2021) (2)
- Testing a theoretical model of imminent fracture risk in elderly women: an observational cohort analysis of the Canadian Multicentre Osteoporosis Study (2020) (2)
- Probing the Scope and Mechanisms of Calcitriol Actions Using Genetically Modified Mouse Models (2020) (2)
- Parity and Lactation Are Not Associated with BMD Loss or Incident Major Fragility Fractures Over 15 Years: Canadian Multicentre Osteoporosis Study (CaMos) (2017) (2)
- Muscle density is associated with fragility fractures in postmenopausal women who are less frail: The CaMOS muscle quality study (2014) (1)
- Skeletal and Reproductive Abnormalities in Pth-Null Mice (2005) (1)
- Parathyroid Hormone: Its Role in Calcium and Phosphate Homeostasis (2014) (1)
- Regulation of parathyroid hormone-related peptide production in vitro by the hypercalcemic leydig cell tumor H-500 (1992) (1)
- Identification and Validation of Targets for Osteoporosis: Evidence from Whole exome Sequencing in 42,263 individuals, CRISPR-Cas9 and murine models (2019) (1)
- Alterations in phosphorus, calcium and PTHrP appear to contribute to defects of dental formation in calcium-sensing receptor deficient mice (2008) (1)
- Genetic Deletion of Menin in Mouse Mesenchymal Stem Cells: An Experimental and Computational Analysis (2022) (1)
- Interaction of parathyroid hormone and of parathyroid hormone-related peptide with target cells in the skeleton (2005) (1)
- Corrigendum: The Relationship Between Proton Pump Inhibitor Use and Longitudinal Change in Bone Mineral Density: A Population-Based From the Canadian Multicentre Osteoporosis Study (CaMos) (2013) (1)
- Opening remarks: establishing a scientific foundation for clinical medicine in the medical curriculum. (2000) (1)
- Author Correction: An atlas of genetic influences on osteoporosis in humans and mice (2019) (1)
- 1st IOF-ESCEO Pre-Clinical Symposium (2011) (1)
- Dietary calcium intake and cardiovascular health: Is there any relationship? (2016) (1)
- Effect of Menin Deletion in Early Osteoblast Lineage on the Mineralization of an In Vitro 3D Osteoid-like Dense Collagen Gel Matrix (2022) (1)
- Studies of the molecular biology of parathyroid hormone-like peptide. (1992) (1)
- Morphological Approach to Biological Action of PTHrP and Vitamin D3 on Endochondral Ossification (2004) (1)
- Role of Mitogen-activated Protein Kinases in the Induction of Parathyroid Hormone-related Peptide 1 (2000) (1)
- Expression and characterization of recombinant human parathyroid hormone-like peptide using a bacterial excretion system (1991) (1)
- Proton Pump Inhibitors Are Associated with Decreased Bone Mineral Density: 1089 (2011) (1)
- Warfarin Use Was Not Associated With Changes in Bone Mineral Density in the Population-Based Canadian Multicentre Osteoporosis Study (CaMos) (2015) (1)
- Value of high-resolution computerized tomography in localizing diseased parathyroid glands. (1984) (1)
- The estrogen debate: to be (old) or not to be (old) (1995) (1)
- The Calcium‐Sensing Receptor and 25‐Hydroxyvitamin D–1α‐Hydroxylase Interact to Modulate Skeletal Growth and Bone Turnover (2018) (1)
- Interaction of Parathyroid Hormone-related Peptide with the Skeleton (2006) (1)
- The Osteoporosis Primer: Molecular genetic analysis of growth factor signaling in bone (2000) (1)
- Role of 1,25-dihydroxyvitamin D in alleviating alveolar bone loss and gingival inflammation in ligature-induced periodontitis. (2022) (1)
- [Table, Table 1. Hypercalcemic Disorders]. (2016) (0)
- Osteoporose-Update 1/2007 (2007) (0)
- Abstract 36: Menin Functions Critically In Mesenchymal Stem Cells And Osteoblast Progenitors To Promote Bone Development And Maintenance In Vivo (2020) (0)
- Grade 1 Vertebral Height Loss is Not Associated with Decreased Quality of Life (2017) (0)
- Table 1, Hypercalcemic Disorders (2013) (0)
- Table 4, Guidelines for Surgery in Primary HPTH (2015) (0)
- The diagnosis of osteoporotic vertebral fractures redux. (2021) (0)
- Modulators of Fam210a and Roles of Fam210a in the Function of Myoblasts (2020) (0)
- [Table, Table 2. Manifestations of Hypercalcemia]. (2016) (0)
- 1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice (2023) (0)
- Reply to: The Association Between Cognitive Decline and Bone Loss and Fracture Risk Is Not Affected by Medication With Anticholinergic Effect (2022) (0)
- Transition to re-fracture and mortality in the elderly : An individualized risk assessment tool for fracture and its outcomes from two large population-based prospective cohort studies. (2017) (0)
- Inhibition of Wnt-1 in human prostate cancer cells blocks prostate cancer cell proliferation, invasion, growth and skeletal metastasis in vitro and in vivo (2006) (0)
- Endocrine aryl hydrocarbon receptor signaling is induced by moderate cutaneous exposure to ultraviolet light (2019) (0)
- Parathyroid Hormone-Related Peptide and Other Systemic Factors in Skeletal Manifestations of Malignancy (2008) (0)
- Abstract 29: An Experimental And Computational Analysis Of Mouse Femur Biomechanics Following The Deletion Of Menin In The Osteoblast Lineage (2020) (0)
- Defective bone mineralization and osteopenia in young adult FGFR3 (cid:1) / (cid:1) mice (2004) (0)
- Table 1, Manifestations of Hypercalcemia (2015) (0)
- 1,25(OH)2D3 contributes to regulating milk calcium content and modulates neonatal bone formation cooperatively with calcium (2008) (0)
- Hip and vertebral fractures increase mortality rates in Canadians (2009) (0)
- ACompilation ofPartial Sequences ofRandomly Selected cDNAClones fromtheRatIncisor (2011) (0)
- Cell Cycle Regulation of Menin Expression 1 (1999) (0)
- Advances in Brief Cell Cycle Regulation of Menin Expression 1 (1999) (0)
- Parathyroid Hormone-related Peptide Role of Mitogen-activated Protein Kinases in the Induction of Updated Version (2000) (0)
- Isolation of hormone-responsive cells from the epiphysis/ metaphysis of rat long bones (1992) (0)
- The 7Q31 locus, containing WNT16, is associated with bone mineral density, osteoporotic fracture and bone strength (2012) (0)
- development and progression of pulmonary hypertension Pathogenic role of calcium-sensing receptors in the (2016) (0)
- Faculty Opinions recommendation of Denosumab and cinacalcet for primary hyperparathyroidism (DENOCINA): a randomised, double-blind, placebo-controlled, phase 3 trial. (2020) (0)
- Wnt16 Is associated with bone mineral density, osteoporotic fracture and bone strength: a Large-Scale Meta-Analysis of Genomewide Association Studies (2012) (0)
- Table 2E, Medication-Induced (2015) (0)
- The coordinated action of parathyroid hormone and parathyroid hormone related peptide is essential for normal fetal axial skeletal development (2010) (0)
- Functions of vitamin D in bone (2018) (0)
- Contributions of Genetically Modified Mouse Models to Understanding the Physiology and Pathophysiology of the 25-Hydroxyvitamin D-1-Alpha Hydroxylase Enzyme (1α(OH)ase) and the Vitamin D Receptor (VDR) (2011) (0)
- Race/ethnic differences in the prevalence of osteoporosis, falls and fractures: a cross-sectional analysis of the Canadian Longitudinal Study on Aging (2022) (0)
- Variation in bone mineral density and fractures over 20 years among Canadians: a comparison of the Canadian Multicenter Osteoporosis Study and the Canadian Longitudinal Study on Aging (2022) (0)
- Pathogenesis of Disturbed Calcium Phosphate Metabolism in Renal Failure-We Have to Rewrite the Textbooks: Transgenic Mice Overexpressing Human Fibroblast Growth Factor 23 (R176Q) Delineate a Putative Role for Parathyroid Hormone in Renal Phosphate Wasting Disorders. Endocrinology 145: 5269-5279, 200 (2005) (0)
- Edinburgh Research Explorer Assessment of gene-by-sex interaction effect on bone mineral density (2018) (0)
- 25-Hydroxyvitamin D-1α Hydroxylase: Studies in Mouse Models and Implications for Human Disease (2009) (0)
- An atlas of genetic influences on osteoporosis in humans and mice (2018) (0)
- CHAPTER 17 – Interaction of Parathyroid Hormone-related Peptide with the Skeleton (2006) (0)
- Table 2C, Granulomatous Disorders Causing Hypercalcemia (2015) (0)
- Author Correction: An atlas of genetic influences on osteoporosis in humans and mice (2019) (0)
- Studies of antiresorptive agents plus parathyroid hormone in the treatment of bone loss (2009) (0)
- Whole-genome sequencing and deep imputation identifies non-coding variants near Engrailed-1 with large effects on bone mineral density and fracture (2015) (0)
- Hypercalcemia Due to PTHrP (2015) (0)
- Activation of human embryonic kidney cell line adenylate cyclase by parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrp) (1992) (0)
- Calcium and Vitamin D: Regulation of Mineral Homeostasis (2006) (0)
- A high-calcium, high-phosphorus, high-lactose diet rescues the intervertebral disc degeneration phenotype induced by the deficiency of 1,25(OH)2D3 (2016) (0)
- The Effect of Bisphosphonates on Mortality Risk Reduction is Partly Mediated Through a Reduction in the Rate of Bone Loss. (2017) (0)
- Table 2, Manifestations of Hypercalcemia (2013) (0)
- Impact of Femoral Neck and Lumbar Spine BMD Discordances on FRAX Probabilities in Women: A Meta-analysis of International Cohorts (2014) (0)
- PTHrP physiology and pathophysiology, and the PTH/PTHrP receptor (2010) (0)
- Parathyroid Hormone-Related Peptide and Malignancy (2005) (0)
- Diminishing benefits of urban living for children and adolescents’ growth and development (2023) (0)
- The calcium sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone (2008) (0)
- Multiglandular Parathyroid Disease in Primary Hyperparathyroidism With Inconclusive Conventional Imaging. (2022) (0)
- Reproductive toxicology. Methacrylamide. (1997) (0)
- Osteoporotic Vertebral Fracture Prevalence Varies Widely: Reply Letter to the Editor (2018) (0)
- Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway (2023) (0)
- Calcium Sensing Receptor Absence Delays Postnatal Brain Development via Direct and Indirect Mechanisms (2013) (0)
- Association Between Dietary Calcium Intake, Dairy Product Consumption and Body Composition Indices in Healthy Postmenopausal Women: A Cross‐Sectional Analysis (2017) (0)
- Human parathyroid hormone-like peptide gene: HindIII and TaqI RFLPs. (1990) (0)
- Abstract 5567: The Ldlr -/- Mouse as a Novel Model of Aortic Calcification: Application of Micro-Computerized Tomography (2009) (0)
- Parathyroid Anatomy, Hormone Synthesis, Secretion, Action, and Receptors (2021) (0)
- List of Contributors (2020) (0)
- Figure 8, [Laboratory approach to the diagnosis...]. (2013) (0)
- The association between body mass index and health-related quality of life: data from CaMos, a stratified population study Wilma M. HopmanClaudie BergerLawrence JosephSusan I. Barr • Yongjun GaoJerilynn C. PriorSuzette PoliquinTanveer Towheed • Tassos AnastassiadesCaMos Research Group (2007) (0)
- Table 2A, Endocrine Disorders Associated with Hypercalcemia (2015) (0)
- Characteristics of Brain Calcitonin Receptors (1989) (0)
- Table 2D, Pediatric Syndromes (2015) (0)
- Table 3, Management of Acute Hypercalcemia (2015) (0)
- A Possible Role of Recurrent Major Depression in Risk of Fracture—Reply (2007) (0)
- Table 2B, Malignancy-Associated Hypercalcemia (MAH) (2015) (0)
- A Fracture Risk Assessment Tool for High Resolution Peripheral Quantitative Computed Tomography. (2023) (0)
- 17β-estradiol plays the anti-osteoporosis role via a novel ESR1-Keap1-Nrf2 axis-mediated stress response activation and Tmem119 upregulation. (2022) (0)
- Epigenomic effects of vitamin D in colorectal cancer. (2022) (0)
- Warfarin use and changes in bone mineral density in the population-based canadian multicentre osteoporosis study (CaMos) (2016) (0)
- Chapter 42 - Hypercalcemia Due to PTHrP (2001) (0)
- The abnormal phenotypes of cartilage and bone in calcium-sensing receptor deficient mice are dependent on the actions of calcium, phosphorus and parathyroid hormone (2008) (0)
- How adequate are follow up times in prospective studies for estimating 10-year absolute risk of fracture among the elderly? (2010) (0)
- Alternatives to Hormonal Replacement Therapy for Prevention of Osteoporosis (2002) (0)
- Deficiency of the PTHrP Nuclear Localization and Carboxyl Terminal Sequences Leads to Pre-mature Skin Aging Partially Mediated by the Upregulation of p27 (2015) (0)
- Management of Endocrine Disorders (1981) (0)
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What Schools Are Affiliated With David Goltzman?
David Goltzman is affiliated with the following schools:
