David Rowitch
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American physician-scientist
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David Rowitchphilosophy Degrees
Philosophy
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#8765
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#1471
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Logic
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#4155
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#662
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David Rowitchbiology Degrees
Biology
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#9570
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#2118
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Developmental Biology
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#99
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#26
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Philosophy Biology
David Rowitch's Degrees
- Doctorate Medicine University of California, San Francisco
- PhD Developmental Biology University of California, San Francisco
Why Is David Rowitch Influential?
(Suggest an Edit or Addition)According to Wikipedia, David Rowitch, FMedSci, FRS is an American physician-scientist known for his contributions to developmental glial biology and treatment of white matter diseases. He heads the Department of Paediatrics at the University of Cambridge and is an adjunct professor of pediatrics at the University of California San Francisco .
David Rowitch's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neurotoxic reactive astrocytes are induced by activated microglia (2017) (4001)
- Conserved Role of Intragenic DNA Methylation in Regulating Alternative Promoters (2010) (1601)
- Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. (2000) (1343)
- Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase (1998) (1270)
- Malignant glioma: genetics and biology of a grave matter. (2001) (1253)
- Single-cell reconstruction of the early maternal–fetal interface in humans (2018) (1163)
- Fate of the mammalian cardiac neural crest. (2000) (1133)
- Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. (2001) (1084)
- Common Developmental Requirement for Olig Function Indicates a Motor Neuron/Oligodendrocyte Connection (2002) (1011)
- Origin of Oligodendrocytes in the Subventricular Zone of the Adult Brain (2006) (947)
- Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System (2000) (853)
- Corridors of Migrating Neurons in Human Brain and Their Decline during Infancy (2011) (755)
- Reactive astrocyte nomenclature, definitions, and future directions (2021) (698)
- Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. (2002) (698)
- Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. (2008) (632)
- Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. (2008) (600)
- Astrocytes and disease: a neurodevelopmental perspective. (2012) (586)
- Developmental genetics of vertebrate glial–cell specification (2010) (574)
- Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. (2009) (569)
- CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. (2010) (560)
- Sonic hedgehog Promotes G1 Cyclin Expression and Sustained Cell Cycle Progression in Mammalian Neuronal Precursors (2000) (531)
- Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors (2003) (527)
- Olig2-Regulated Lineage-Restricted Pathway Controls Replication Competence in Neural Stem Cells and Malignant Glioma (2007) (479)
- Single-cell genomics identifies cell type–specific molecular changes in autism (2019) (431)
- Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair (2012) (430)
- Glial specification in the vertebrate neural tube (2004) (424)
- Myelin Gene Regulatory Factor Is a Critical Transcriptional Regulator Required for CNS Myelination (2009) (423)
- Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis (2004) (421)
- bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS (2004) (415)
- Challenges to curing primary brain tumours (2019) (414)
- Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest (2003) (405)
- Sonic hedgehog Regulates Proliferation and Inhibits Differentiation of CNS Precursor Cells (1999) (397)
- Functional diversity of astrocytes in neural circuit regulation (2016) (395)
- The Oligodendroglial Lineage Marker OLIG2 Is Universally Expressed in Diffuse Gliomas (2004) (393)
- Smaller inner ear sensory epithelia in Neurog1 null mice are related to earlier hair cell cycle exit (2005) (382)
- Expression pattern of the transcription factor Olig2 in response to brain injuries: implications for neuronal repair. (2005) (379)
- Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. (2001) (346)
- Dlx1 and Dlx2 Control Neuronal versus Oligodendroglial Cell Fate Acquisition in the Developing Forebrain (2007) (344)
- Glioma Stem Cells: A Midterm Exam (2008) (341)
- Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. (1996) (324)
- Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination (2011) (317)
- A Dramatic Increase of C1q Protein in the CNS during Normal Aging (2013) (315)
- Development of mice expressing a single D-type cyclin. (2002) (304)
- Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade (2009) (303)
- Myelin regeneration: a recapitulation of development? (2011) (288)
- Oligodendrocyte-Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis (2014) (288)
- A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. (2006) (286)
- Neuronal vulnerability and multilineage diversity in multiple sclerosis (2019) (275)
- Extensive migration of young neurons into the infant human frontal lobe (2016) (269)
- Astrocyte development and heterogeneity. (2014) (269)
- Neural Stem Cell Engraftment and Myelination in the Human Brain (2012) (267)
- Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa. (2004) (256)
- Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas. (2010) (252)
- Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma (2011) (248)
- Astrocyte-encoded positional cues maintain sensorimotor circuit integrity (2014) (243)
- RESEARCH ARTICLE: Myelin Abnormalities without Oligodendrocyte Loss in Periventricular Leukomalacia (2008) (237)
- Olig gene function in CNS development and disease (2006) (235)
- Molecular diversity of astrocytes with implications for neurological disorders. (2004) (230)
- Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors (2004) (229)
- Niche stiffness underlies the aging of central nervous system progenitor cells (2019) (227)
- Brain charts for the human lifespan (2021) (224)
- Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map (2020) (220)
- Development of NG2 neural progenitor cells requires Olig gene function (2006) (217)
- The Proneural Gene Mash1 Specifies an Early Population of Telencephalic Oligodendrocytes (2007) (208)
- Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma. (2006) (200)
- Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination (2011) (196)
- A Centrosomal Cdc20-APC Pathway Controls Dendrite Morphogenesis in Postmitotic Neurons (2009) (191)
- The metabolic defect of methionine dependence occurs frequently in human tumor cell lines. (1983) (186)
- Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination (2009) (186)
- Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases (2012) (181)
- Overcoming remyelination failure in multiple sclerosis and other myelin disorders (2010) (179)
- GDNF induces branching and increased cell proliferation in the ureter of the mouse. (1997) (178)
- An ‘oligarchy’ rules neural development (2002) (175)
- Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors (2001) (172)
- Insulin‐like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination (2007) (172)
- Specification of astrocytes by bHLH protein SCL in a restricted region of the neural tube (2005) (170)
- NIH Consensus Development Conference Statement: Inhaled Nitric-Oxide Therapy for Premature Infants (2011) (162)
- Origin and dynamics of oligodendrocytes in the developing brain: Implications for perinatal white matter injury (2017) (161)
- Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1 (1995) (160)
- N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth. (2006) (160)
- Evolving Concepts of Gliogenesis: A Look Way Back and Ahead to the Next 25 Years (2013) (153)
- Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers. (2004) (152)
- Targeted Therapy for BRAFV600E Malignant Astrocytoma (2011) (147)
- Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination (2010) (146)
- A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. (2018) (145)
- The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. (2011) (144)
- Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube (2001) (141)
- Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2 (2012) (139)
- Whole genome sequencing reveals that genetic conditions are frequent in intensively ill children (2019) (139)
- The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors. (2005) (135)
- Oligodendrocyte development in the spinal cord and telencephalon: common themes and new perspectives (2001) (126)
- A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool (2007) (123)
- A Genome-Wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development (2009) (120)
- Species-Dependent Posttranscriptional Regulation of NOS1 by FMRP in the Developing Cerebral Cortex (2012) (120)
- Transcription factor co‐expression patterns indicate heterogeneity of oligodendroglial subpopulations in adult spinal cord (2006) (119)
- Hypomyelinating leukodystrophies: Translational research progress and prospects (2014) (119)
- Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex (2001) (117)
- Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism. (2009) (114)
- Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration (2020) (110)
- Phosphorylation State of Olig2 Regulates Proliferation of Neural Progenitors (2011) (110)
- Towards improved animal models of neonatal white matter injury associated with cerebral palsy (2010) (106)
- Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage (2017) (106)
- Extent of DNA methylation in human tumor cells. (1983) (103)
- Forkhead Transcription Factor FoxM1 Regulates Mitotic Entry and Prevents Spindle Defects in Cerebellar Granule Neuron Precursors (2007) (101)
- Six3 promotes the formation of ectopic optic vesicle‐like structures in mouse embryos (2001) (100)
- Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer (2014) (100)
- Histology-Based Expression Profiling Yields Novel Prognostic Markers in Human Glioblastoma (2005) (98)
- Sonic Hedgehog Is Required during an Early Phase of Oligodendrocyte Development in Mammalian Brain (2001) (96)
- Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength (2018) (92)
- Behaviorally consequential astrocytic regulation of neural circuits (2020) (90)
- Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice. (2003) (89)
- A FOXO-Pak1 transcriptional pathway controls neuronal polarity. (2010) (87)
- Oligodendrocyte Regeneration after Neonatal Hypoxia Requires FoxO1-Mediated p27Kip1 Expression (2012) (83)
- Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma. (2012) (82)
- Reactive astrocyte COX2‐PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury (2017) (81)
- Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem (2012) (81)
- Identification of the Kappa-Opioid Receptor as a Therapeutic Target for Oligodendrocyte Remyelination (2016) (80)
- Origins and Proliferative States of Human Oligodendrocyte Precursor Cells (2020) (76)
- Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy (2012) (76)
- Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach (2002) (76)
- Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate. (1998) (75)
- Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain. (2019) (74)
- Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord (2012) (72)
- Expression of Oligodendroglial and Astrocytic Lineage Markers in Diffuse Gliomas: Use of YKL-40, ApoE, ASCL1, and NKX2-2 (2006) (72)
- Medulloblastoma: a problem of developmental biology. (2002) (71)
- Olig2 expression, GFAP, p53 and 1p loss analysis contribute to glioma subclassification (2005) (71)
- A Small-Molecule Smoothened Agonist Prevents Glucocorticoid-Induced Neonatal Cerebellar Injury (2011) (71)
- Interactions between DNA and coat protein in the structure and assembly of filamentous bacteriophage fd (1987) (70)
- Cross-Repressive Interaction of the Olig2 and Nkx2.2 Transcription Factors in Developing Neural Tube Associated with Formation of a Specific Physical Complex (2003) (69)
- Dysregulation of astrocyte extracellular signaling in Costello syndrome (2015) (69)
- Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. (2012) (68)
- Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes (2017) (65)
- Topical iodine and neonatal hypothyroidism. (1995) (63)
- Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity (2018) (62)
- Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord. (2012) (62)
- Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes (2002) (61)
- Neurocritical Care for Neonates (2010) (61)
- Protein Kinase C-associated Kinase (PKK), a Novel Membrane-associated, Ankyrin Repeat-containing Protein Kinase* (2001) (60)
- Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives. (2001) (58)
- OLIG2 is differentially expressed in pediatric astrocytic and in ependymal neoplasms (2010) (57)
- Olig1 Function Is Required to Repress Dlx1/2 and Interneuron Production in Mammalian Brain (2014) (56)
- Identification of molecular compartments and genetic circuitry in the developing mammalian kidney (2012) (55)
- Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. (2019) (55)
- Expression profiling of Aldh1l1‐precursors in the developing spinal cord reveals glial lineage‐specific genes and direct Sox9‐Nfe2l1 interactions (2013) (55)
- A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain (1995) (54)
- Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia (2003) (53)
- Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury (2016) (52)
- Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis (2018) (50)
- β-catenin function is required for cerebellar morphogenesis (2007) (50)
- NIH consensus development conference (2010) (49)
- Myelin Regeneration in Multiple Sclerosis: Targeting Endogenous Stem Cells (2011) (49)
- Cerebellar ‘transcriptome’ reveals cell-type and stage-specific expression during postnatal development and tumorigenesis (2006) (47)
- The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors (2013) (42)
- Astrocytes: The Final Frontier… (2016) (42)
- Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease. (2013) (42)
- Expression of the Homeobox‐containing Genes EN1 and EN2 in Human Fetal Midgestational Medulla and Cerebellum (1997) (41)
- Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome (2015) (38)
- An update on human astrocytes and their role in development and disease (2020) (38)
- Disease specific therapies in leukodystrophies and leukoencephalopathies. (2015) (38)
- Beta-catenin function is required for cerebellar morphogenesis. (2007) (37)
- Ablation of NG2 Proteoglycan Leads to Deficits in Brown Fat Function and to Adult Onset Obesity (2012) (37)
- Cerebellar abnormalities following hypoxia alone compared to hypoxic–ischemic forebrain injury in the developing rat brain (2011) (37)
- Lineage-Restricted OLIG2-RTK Signaling Governs the Molecular Subtype of Glioma Stem-like Cells. (2016) (35)
- Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury (2020) (33)
- Long-Term Safety, Immunologic Response, and Imaging Outcomes following Neural Stem Cell Transplantation for Pelizaeus-Merzbacher Disease (2019) (32)
- Postnatal growth of the human pons: A morphometric and immunohistochemical analysis (2015) (32)
- Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum. (1999) (30)
- Diversity and Function of Glial Cell Types in Multiple Sclerosis. (2021) (30)
- Nuclear Localization of the Mitochondrial Factor HIGD1A during Metabolic Stress (2013) (29)
- Expression Profiling of Aldh 1 l 1-Precursors in the Developing Spinal Cord Reveals Glial Lineage-Specific Genes and Direct Sox 9-Nfe 2 l 1 Interactions (2013) (29)
- Evidence that nuclear factor IA inhibits repair after white matter injury (2012) (29)
- MC3R links nutritional state to childhood growth and the timing of puberty (2021) (28)
- Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit (2020) (27)
- Identification of proliferative progenitors associated with prominent postnatal growth of the pons (2016) (26)
- Genetic correlates of phenotypic heterogeneity in autism (2020) (26)
- A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2. (2017) (25)
- Variable electrostatic interaction between DNA and coat protein in filamentous bacteriophage assembly. (1988) (25)
- Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma. (2010) (23)
- Cerebellar cortical lamination and foliation require cyclin A2. (2014) (22)
- Olig1 function is required for remyelination potential of transplanted neural progenitor cells in a model of viral-induced demyelination (2012) (21)
- Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. (2006) (21)
- Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence (2021) (20)
- NIH consensus development conference: Inhaled nitric oxide therapy for premature infants. (2010) (19)
- Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury (2017) (19)
- Single-cell reconstruction of the early maternal–fetal interface in humans (2018) (19)
- Myelin Restoration: Progress and Prospects for Human Cell Replacement Therapies (2011) (18)
- Cystic malformation of the posterior cerebellar vermis in transgenic mice that ectopically express Engrailed-1, a homeodomain transcription factor. (1999) (17)
- An Amino Terminal Phosphorylation Motif Regulates Intranuclear Compartmentalization of Olig2 in Neural Progenitor Cells (2014) (17)
- NEONATAL HERPES SIMPLEX VIRUS INFECTION PRESENTING AS FULMINANT LIVER FAILURE (1995) (17)
- The Role of the Neurointensive Care Nursery for Neonatal Encephalopathy. (2016) (17)
- Expression and function of Nkx6.3 in vertebrate hindbrain (2008) (16)
- Synchronization of goat fibroblast cells at quiescent stage and determination of their transition from G0 to G1 by detection of cyclin D1 mRNA. (2004) (14)
- The neurointensive nursery: concept, development, and insights gained (2019) (13)
- Single-cell in situ transcriptomic map of astrocyte cortical layer diversity (2018) (13)
- Mechanisms of astrocyte development (2020) (13)
- The role of prenatal steroids at 34–36 weeks of gestation (2017) (12)
- Cell interactions in patterning the mammalian midbrain. (1997) (11)
- Olig1 is required for noggin‐induced neonatal myelin repair (2017) (11)
- Niche stiffness underlies the ageing of central nervous system progenitor cells (2019) (11)
- Ferret brain possesses young interneuron collections equivalent to human postnatal migratory streams (2019) (9)
- Moderate-Grade Germinal Matrix Haemorrhage Activates Cell Division in the Neonatal Mouse Subventricular Zone (2017) (8)
- Sustaining careers of physician-scientists in neonatology and pediatric critical care medicine: formulating supportive departmental policies (2016) (8)
- Cucurbit[8]uril-Derived Graphene Hydrogels. (2019) (7)
- Evidence for glutamine synthetase function in mouse spinal cord oligodendrocytes (2021) (7)
- Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury (2018) (7)
- Cancer Therapy : Preclinical Targeted Therapy for BRAFV 600 E Malignant Astrocytoma (2011) (6)
- Faculty Opinions recommendation of m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. (2020) (6)
- Effect of coat protein mutations in bacteriophage fd studied by sedimentation analysis. (1992) (6)
- Author Correction: Niche stiffness underlies the ageing of central nervous system progenitor cells (2019) (6)
- 803 (2019) (6)
- Nutritional signals rapidly activate oligodendrocyte differentiation in the adult hypothalamic median eminence (2019) (5)
- Faculty Opinions recommendation of Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. (2013) (5)
- On-chip perivascular niche supporting stemness of patient-derived glioma cells in a serum-free, flowable culture† (2021) (5)
- Cloning and expression of the filamentous bacteriophage Pf1 major coat protein gene in Escherichia coli. Membrane protein processing and virus assembly. (1987) (4)
- Neuroprotective effects of Sonic hedgehog agonist SAG in a rat model of neonatal stroke (2021) (4)
- Time-resolved single-cell RNAseq profiling identifies a novel Fabp5-expressing subpopulation of inflammatory myeloid cells in chronic spinal cord injury (2020) (4)
- Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion (2022) (4)
- Corrigendum: Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer (2014) (3)
- Neural stem cell engraftment and myelination in the human brain (Science Translational Medicine (1988) 17, (351-360)) (2012) (3)
- DEVELOPMENT AND DISEASE Loss of Emx 2 function leads to ectopic expression of Wnt 1 in the developing telencephalon and cortical dysplasia (2003) (3)
- Comprar Fetal And Neonatal Physiology, 2 Vols. (Online And Print) 5th Ed. | R. Polin | 9780323352147 | Elsevier España (2016) (3)
- Molecular diversity and lineage commitment of human interneuron progenitors (2021) (2)
- Refinements and considerations for trio whole-genome sequence analysis when investigating Mendelian diseases presenting in early childhood (2022) (2)
- Oligodendrocytes: Cells of origin for white matter injury in the developing brain (2016) (2)
- Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells (2022) (2)
- Multicenter Consensus Approach to Evaluation of Neonatal Hypotonia in the Genomic Era: A Review. (2022) (2)
- Faculty Opinions recommendation of Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity. (2019) (1)
- Region-restricted origins of astrocytes in the developing spinal cord (2008) (1)
- Publisher Correction: Brain charts for the human lifespan (2022) (1)
- Erratum: Molecular diversity of astrocytes with implications for neurological disorders (Proceedings of the National Academy of Sciencs of the United States of America (June 1, 2004) 101, 22 (8384-8389)) (2004) (1)
- Faculty of 1000 evaluation for Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development. (2018) (1)
- Applying support-vector machine learning algorithms toward predicting host-guest interactions with cucurbit[7]uril. (2020) (1)
- OLIG2 (oligodendrocyte lineage transcription factor 2) (2011) (1)
- Summary Hedgehog and PI-3 kinase signaling converge on Nmyc 1 to promote cell cycle progression in cerebellar neuronal precursors (2003) (1)
- Characterising a SOX2+ OLIG2+ glioma stem cell using Crispr-engineered fluorescent reporters in primary patient-derived GBM and DIPG cells. (2019) (1)
- Faculty Opinions recommendation of Saltatory Conduction along Myelinated Axons Involves a Periaxonal Nanocircuit. (2020) (1)
- Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination (2023) (1)
- On-chip perivascular niche with patient-derived glioma cells (2020) (1)
- Faculty Opinions recommendation of Three-dimensional intact-tissue sequencing of single-cell transcriptional states. (2018) (1)
- Faculty Opinions recommendation of Epigenetic control of region-specific transcriptional programs in mouse cerebellar and cortical astrocytes. (2021) (1)
- Supplement: GLIA Bilbao 2017: Abstracts Oral Presentations, Posters, Indexes. (2017) (1)
- A classification of video-conferencing related illness: the zoomnotic diseases. (2020) (1)
- Reactive astrocyte COX 2-PGE 2 production inhibits oligodendrocyte 1 maturation in neonatal white matter injury 2 3 Running Title : PGE 2 inhibits OPC maturation 4 5 (2017) (1)
- Abstract 1446: Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem (2012) (1)
- Faculty Opinions recommendation of Oligodendrocytes provide antioxidant defense function for neurons by secreting ferritin heavy chain. (2020) (1)
- A role for C1q in normal brain aging (2012) (1)
- Faculty Opinions recommendation of Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice. (2020) (1)
- DNA-protein interactions and DNA packaging in filamentous bacteriophages (1986) (1)
- Faculty Opinions recommendation of Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization. (2019) (0)
- Faculty Opinions recommendation of Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling. (2016) (0)
- Reply to ‘Assembling the brain trust: the multidisciplinary imperative in neuro-oncology’ (2019) (0)
- Faculty Opinions recommendation of Apelin signaling drives vascular endothelial cells towards a pro-angiogenic state. (2020) (0)
- Dandy-Walker Malformation in Transgenic Mice That Ectopically Express Engrailed-1, A Homeodomain Transcription Factor, in the Embryonic Brain • 302 (1998) (0)
- Predicting Macrocyclic Molecular Recognition with Machine Learning (2019) (0)
- Oligodendrocyte-encoded Kir4.1 function is required for integrity. (2018) (0)
- New Recipes for Myelinating Oligodendrocytes. (2018) (0)
- PRECLINICAL EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY (2010) (0)
- Faculty Opinions recommendation of Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia. (2019) (0)
- The oligodendrocyte lineage genes Olig1 and Olig2 in CNS development (2008) (0)
- Faculty Opinions recommendation of Live-imaging of astrocyte morphogenesis and function in zebrafish neural circuits. (2020) (0)
- Optimising the health-care experiences of babies, children, and young people (2021) (0)
- David Rowitch (2017) (0)
- Chapter 33 – ‘Glial’ Biology: Has it Come to the Beginning of the End? (2013) (0)
- Edinburgh Explorer Myelin regeneration in multiple sclerosis (2011) (0)
- Therapy for Premature Infants NIH Consensus Development Conference Statement: Inhaled Nitric-Oxide (2011) (0)
- PM-03ROLE OF Olig2 PHOSPHORYLATION IN PEDIATRIC GLIOMA FORMATION (2014) (0)
- Inhibiting the Prostaglandin Pathway for Neonatal Neuroprotection (2015) (0)
- I-05 Astrocytes (2017) (0)
- Novel regulation of PDGFRα activation in Glioblastoma (2012) (0)
- vulnerability and multilineage diversity in multiple sclerosis. (2019) (0)
- Faculty Opinions recommendation of Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain. (2018) (0)
- Faculty of 1000 evaluation for Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers. (2018) (0)
- Response to: is zoomnosis an human-driven human zoonosis? A call for action. (2021) (0)
- Abstract LB-206: Role of Olig2 phosphorylation in pediatric glioma formation (2014) (0)
- Faculty Opinions recommendation of Motor skill learning requires active central myelination. (2014) (0)
- as regulatory therapeutic target in newborn brain injury and remyelination. (2016) (0)
- Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map (2020) (0)
- Symposium S9: Molecular Cues Directing Progenitor Cell Migration/Differentiation: Can We Enhance These Processes in the Diseased Nervous System? (2004) (0)
- Faculty Opinions recommendation of CNS myelin wrapping is driven by actin disassembly. (2015) (0)
- Faculty Opinions recommendation of Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset. (2020) (0)
- 803: WHOLE GENOME SEQUENCE ANALYSIS FOR RAPID DIAGNOSIS OF SEVERELY ILL CHILDREN IN INTENSIVE CARE (2019) (0)
- Abstract SY02-04: Overlapping mechanisms in CNS development and gliomagenesis (2014) (0)
- Silencing neuroinflammatory reactive astrocyte activating factors ameliorates disease outcomes in perinatal white matter injury (2022) (0)
- during both Normal and Neoplastic Cerebellar Growth Is an Essential Downstream Effector of Shh Signaling myc (0)
- Financial Support: M.C. acknowledges fellowship awards from the American Heart Association and The Children’s Heart Foundation and funding support from a Career Development Grant awarded by Cerebral Palsy (2021) (0)
- TMIC-49. POTASSIUM CHANNEL KIR4.1 AND GLUTAMINE SYNTHETASE ARE DYSREGULATED IN GLIOMA (2017) (0)
- Faculty Opinions recommendation of Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis. (2020) (0)
- Development of functionally heterogeneous astrocytes in mammalian CNS (2017) (0)
- Supplementary Material for: Moderate-Grade Germinal Matrix Haemorrhage Activates Cell Division in the Neonatal Mouse Subventricular Zone (2017) (0)
- Author index (1995) (0)
- Faculty Opinions recommendation of Multifunctional glial support by Semper cells in the Drosophila retina. (2017) (0)
- Faculty Opinions recommendation of Synapse location during growth depends on glia location. (2013) (0)
- Clinical and Neurophysiologic Phenotypes in Neonates With BRAT1 Encephalopathy (2023) (0)
- ANGI-04Olig2 REGULATES Wnt7b EXPRESSION AND VASCULATURE CHARACTERISTICS IN GLIOMA (2015) (0)
- A retroviral origin of vertebrate myelin (2022) (0)
- The neuroprotective effects of Sonic hedgehog pathway agonist SAG in a rat model of neonatal stroke (2021) (0)
- CS-34EVIDENCE FOR OLIGODENDROCYTE ORIGINS OF PEDIATRIC GLIOMA (2014) (0)
- Title Long-Term Safety , Immunologic Response , and Imaging Outcomes following Neural Stem Cell Transplantation for Pelizaeus-Merzbacher Disease (2019) (0)
- Macrophage activation in perinatal brain injury (2015) (0)
- Author Correction: Niche stiffness underlies the ageing of central nervous system progenitor cells (2019) (0)
- Faculty Opinions recommendation of Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system. (2015) (0)
- Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury (2017) (0)
- A golden age for glial biology (2020) (0)
- Regulation of Early Events in Cell Cycle Progression by Hedgehog Signaling in CNS Development and Tumorigenesis (2006) (0)
- The Microglial Secretome Regulates Flavivirus Infection of Developing and Malignant Human Neural Stem Cells (2022) (0)
- Novel origins of medulloblastoma from Olig2+ progenitors of the rhombic lip (2008) (0)
- Identifying the Zika Virus Target Cell in Malignant Glioma (2019) (0)
- Olig2 function in adult neural stem and progenitor cells (2008) (0)
- Glioma invasion: Identification of determinants of invasion using time‐lapse imaging (2008) (0)
- Heine Neonatal Cerebellar Injury A Small-Molecule Smoothened Agonist Prevents Glucocorticoid-Induced (2011) (0)
- Correction (2002) (0)
- Faculty Opinions recommendation of Gene suppressing therapy for Pelizaeus-Merzbacher disease using artificial microRNA. (2019) (0)
- Macrophage activation in perinatal white matter injury (2015) (0)
- Separate progenitors for somatic and visceral motor neurons in mouse spinal cord. (2013) (0)
- The Myeloid Cell Secretome Regulates Zika Flavivirus Infection of Developing and Malignant Human Neural Progenitor Cells (2022) (0)
- Faculty Opinions recommendation of Capillary pericytes regulate cerebral blood flow in health and disease. (2014) (0)
- Role of academic medical centers in cell-based therapeutic clinical trials. (2011) (0)
- Faculty Opinions recommendation of Microglial remodeling of the extracellular matrix promotes synapse plasticity. (2020) (0)
- Faculty Opinions recommendation of Oligodendrocyte neurofascin independently regulates both myelin targeting and sheath growth in the CNS. (2019) (0)
- Single-cell reconstruction of the human early maternal-fetal interface (2018) (0)
- Abstract 4186: Development of a novel, genetically faithful model of pediatric glioblastoma (2010) (0)
- ID4 function Antagonizes Olig1 and Olig2 to suppress aggressive gliomagenesis (2013) (0)
- Abstract 1944: Divergent effects of BRAF activation in neural stem and progenitor-like glioblastoma cells (2014) (0)
- Faculty Opinions recommendation of Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution. (2019) (0)
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