David Hershel Alpers
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American gastroenterologist
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David Hershel Alpers's Degrees
- Doctorate Medicine Harvard University
- Bachelors Chemistry Harvard University
Why Is David Hershel Alpers Influential?
(Suggest an Edit or Addition)According to Wikipedia, David Hershel Alpers is a gastroenterologist, researcher, professor, and former president of the American Gastroenterological Association . Early life and education David Hershel Alpers was born 9 May 1935 in Philadelphia, Pennsylvania. He received his M.D. from Harvard Medical School in 1960 and completed training in internal medicine at Massachusetts General Hospital . He studied molecular biology at the National Institute of Health under Gordon Tomkins before returning to MGH for gastroenterology fellowship and junior faculty positions .
David Hershel Alpers's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Clindamycin-associated colitis. A prospective study. (1974) (572)
- Nutrition support in clinical practice: review of published data and recommendations for future research directions. (1997) (426)
- Fundamentals of neurogastroenterology (1999) (308)
- Nutrition support in clinical practice: review of published data and recommendations for future research directions. Summary of a conference sponsored by the National Institutes of Health, American Society for Parenteral and Enteral Nutrition, and American Society for Clinical Nutrition. (1997) (300)
- Psychiatric illness and the irritable bowel syndrome. Practical implications for the primary physician. (1976) (258)
- Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women (2004) (256)
- Accelerated Fat Absorption in Intestinal Alkaline Phosphatase Knockout Mice (2003) (184)
- Nutrition support in clinical practice: review of published data and recommendations for future research directions. National Institutes of Health, American Society for Parenteral and Enteral Nutrition, and American Society for Clinical Nutrition. (1997) (178)
- Regulation of the biosynthesis of two distinct fatty acid-binding proteins in rat liver and intestine. Influences of sex difference and of clofibrate. (1985) (177)
- Caco‐2 cells express a combination of colonocyte and enterocyte phenotypes (1998) (176)
- The nucleotide sequence of rat liver fatty acid binding protein mRNA. (1983) (173)
- Antidepressant therapy in 138 patients with irritable bowel syndrome: a five‐year clinical experience (1994) (163)
- Do life events or depression exacerbate inflammatory bowel disease? A prospective study. (1991) (162)
- Effect of proteolytic enzymes on the binding of cobalamin to R protein and intrinsic factor. In vitro evidence that a failure to partially degrade R protein is responsible for cobalamin malabsorption in pancreatic insufficiency. (1978) (158)
- Tissue specific expression and developmental regulation of two genes coding for rat fatty acid binding proteins. (1985) (152)
- Cloning of a cDNA encoding rat intestinal fatty acid binding protein. (1984) (151)
- Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database (2015) (145)
- The possible role of pancreatic proteases in the turnover of intestinal brush border proteins. (1975) (144)
- The relation of ulcerative colitis to psychiatric factors: a review of findings and methods. (1990) (141)
- Oleic acid stimulation of apolipoprotein B secretion from HepG2 and Caco-2 cells occurs post-transcriptionally. (1990) (140)
- Protein synthesis in intestinal mucosa: the effect of route of administration of precursor amino acids. (1972) (132)
- The irritable colon syndrome and psychiatric illness. (1973) (130)
- Relationship of functional gastrointestinal disorders and psychiatric disorders: implications for treatment. (2007) (124)
- Intestinal apoproteins during fat absorption. (1978) (115)
- Light microscopic immunocytochemical localization of hepatic and intestinal types of fatty acid-binding proteins in rat small intestine. (1986) (114)
- American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte (2003) (108)
- Diagnostic features of clindamycin-associated pseudomembranous colitis. (1974) (105)
- ERK and p38 MAP kinase pathways are mediators of intestinal epithelial wound-induced signal transduction. (1997) (105)
- Effect of secreted Bacteroides proteases on human intestinal brush border hydrolases. (1980) (102)
- The presentation of irritable bowel syndrome in the context of somatization disorder. (2004) (101)
- The primary translation product of rat intestinal apolipoprotein A-I mRNA is an unusual preproprotein. (1982) (99)
- The turnover of disaccharidases and brush border proteins in rat intestine. (1971) (98)
- The Association of Irritable Bowel Syndrome and Somatization Disorder (2001) (93)
- Properties of human intestinal glucoamylase. (1973) (92)
- Isolation and characterization of a small intestinal surfactant-like particle containing alkaline phosphatase and other digestive enzymes. (1989) (92)
- Barostat testing of rectal sensation and compliance in humans: comparison of results across two centres and overall reproducibility (2005) (90)
- The relation of size to the relative rates of degradation of intestinal brush border proteins. (1972) (86)
- A Study of the Association Between Crohn's Disease and Psychiatric Illness (1984) (86)
- Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells. (1994) (85)
- Purification, properties, and immunochemical localization of a receptor for intrinsic factor-cobalamin complex in the rat kidney. (1988) (84)
- The alpha 1-antitrypsin gene is expressed in a human intestinal epithelial cell line. (1989) (83)
- Absorption and transport of cobalamin (vitamin B12). (1982) (82)
- Intestinal surfactant-like material. A novel secretory product of the rat enterocyte. (1989) (82)
- Isolation and characterization of the ileal receptor for intrinsic factor-cobalamin. (1981) (81)
- The mechanism of elevated alkaline phosphatase activity after bile duct ligation in the rat (1986) (81)
- Enteral feeding and gut atrophy (2002) (78)
- A study of the association between Crohn's disease and psychiatric illness. (1984) (78)
- Characterization and comparison of soluble and membranous forms of intestinal alkaline phosphatase from the suckling rat. (1981) (78)
- Cloning of a complementary deoxyribonucleic acid encoding a portion of rat intestinal preapolipoprotein AIV messenger ribonucleic acid. (1982) (77)
- Diet and irritable bowel syndrome (2006) (76)
- A SPECTROPHOTOMETRIC ASSAY FOR THIOGALACTOSIDE TRANSACETYLASE. (1965) (76)
- Increased lymph alkaline phosphatase after fat feeding: effects of medium chain triglycerides and inhibition of protein synthesis. (1970) (73)
- Glutamine: do the data support the cause for glutamine supplementation in humans? (2006) (72)
- Development of drugs for gastrointestinal motor disorders: translating science to clinical need (2008) (69)
- Immunolocalization of alkaline phosphatase and surfactant-like particle proteins in rat duodenum during fat absorption. (1996) (68)
- Synthesis and parallel secretion of rat intestinal alkaline phosphatase and a surfactant-like particle protein. (1995) (67)
- A novel phosphatase upregulated in Akp3 knockout mice. (2007) (64)
- Intestinal fatty acid binding protein may favor differential apical fatty acid binding in the intestine. (2000) (64)
- A review of studies of psychiatric factors in Crohn's disease: etiologic implications. (1994) (63)
- Development of intestinal brush border membrane proteins in the rat. (1977) (63)
- Manual of Nutritional Therapeutics (1983) (61)
- Blood group antigenicity of purified human intestinal disaccharidases. (1973) (61)
- Protein synthesis by rat intestinal mucosa. The role of ribonuclease. (1967) (60)
- Starch and glucose oligosaccharides protect salivary-type amylase activity at acid pH. (1988) (60)
- Separation and Isolation of Rat and Human Intestinal β-Galactosidases (1969) (60)
- Isolation and sequence analysis of variant forms of human transcobalamin II. (1993) (60)
- A possible role for rat intestinal surfactant-like particles in transepithelial triacylglycerol transport. (1994) (59)
- Disruption of the murine intestinal alkaline phosphatase gene Akp3 impairs lipid transcytosis and induces visceral fat accumulation and hepatic steatosis. (2007) (59)
- Stimulation of intestinal mucosal proliferation by vitamin D. (1973) (58)
- The characterization of rat intestinal amylase. (1970) (58)
- Regulation of small intestinal protein metabolism. (1973) (58)
- Isolation and characterization of surfactant-like particles in rat and human colon. (1997) (57)
- Rat intestinal alkaline phosphatase secretion into lumen and serum is coordinately regulated. (1991) (56)
- Immunocytochemical localization of the intrinsic factor-cobalamin receptor in dog-ileum: distribution of intracellular receptor during cell maturation (1984) (55)
- Human gastric intrinsic factor: characterization of cDNA and genomic clones and localization to human chromosome 11. (1991) (55)
- Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-Å resolution (2007) (55)
- A controlled study of the association between ulcerative colitis and psychiatric diagnoses (1982) (54)
- Clostridium Butyricum MIYAIRI 588 Improves High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Rats (2013) (53)
- Distribution of intrinsic factor-vitamin B12 receptors in human intestine. (1977) (52)
- Health outcomes associated with vegetarian diets: An umbrella review of systematic reviews and meta-analyses. (2020) (51)
- Rat enterocytes secrete SLPs containing alkaline phosphatase and cubilin in response to corn oil feeding. (2003) (50)
- Serum amylase determinations and amylase to creatinine clearance ratios in patients with chronic renal insufficiency. (1976) (50)
- Characterization of proteins in rat and human intestinal surfactant-like particles. (1993) (48)
- Characterization of ileal vitamin B12 Binding using homogeneous human and hog intrinsic factors. (1973) (48)
- Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes. (1989) (47)
- Vitamin B12 transporters. (1999) (47)
- Effect of the NK3 receptor antagonist, talnetant, on rectal sensory function and compliance in healthy humans (2007) (47)
- Molecular cloning and expression of a cDNA encoding the membrane-associated rat intestinal alkaline phosphatase. (1990) (47)
- Use of clonidine to decrease intestinal fluid losses in patients with high-output short-bowel syndrome. (2004) (46)
- Ontogenic and phylogenic studies of intestinal, hepatic, and placental alkaline phosphatases: Evidence that intestinal alkaline phosphatase is a late evolutionary development* (1986) (45)
- Complete histologic normalisation is associated with reduced risk of relapse among patients with ulcerative colitis in complete endoscopic remission (2019) (43)
- Is glutamine a unique fuel for small intestinal cells? (2000) (42)
- Hepatic clearance of rat plasma intestinal alkaline phosphatase. (1984) (42)
- Secretion of hepatic and intestinal alkaline phosphatases: similarities and differences. (1990) (42)
- Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration. (2009) (42)
- Identification of a 4-base deletion in the gene in inherited intrinsic factor deficiency. (2004) (41)
- Multiple molecular forms of -galactosidase (1965) (41)
- Regulation of intestinal and hepatic apoprotein synthesis after chronic fat and cholesterol feeding. (1988) (41)
- Adenosine cyclic 3':5'-monophosphate-mediated transport of neutral and dibasic amino acids in jejunal mucosa. (1973) (41)
- Pericrypt eosinophilic enterocolitis and chronic diarrhea. (1992) (40)
- Effect of exocrine pancreatic insufficiency on small intestine in the mouse (1978) (40)
- Role of the free amino acid pool of the intestine in protein synthesis. (1972) (39)
- THE ORDER OF INDUCTION AND DEINDUCTION OF THE ENZYMES OF THE LACTOSE OPERON IN E. COLI. (1965) (39)
- Sequential transcription of the genes of the lactose operon and its regulation by protein synthesis. (1966) (38)
- Expression of intrinsic factor and pepsinogen in the rat stomach identifies a subset of parietal cells. (1998) (38)
- Jejunoileal bypass. Late metabolic sequelae and weight gain. (1980) (37)
- Pathophysiology of diseases involving intestinal brush-border proteins. (1977) (37)
- Detection of apolipoprotein C in human and rat enterocytes (1980) (37)
- The two mRNAs encoding rat intestinal alkaline phosphatase represent two distinct nucleotide sequences. (1992) (36)
- The Relevance of the Colon to Zinc Nutrition (2015) (36)
- Development and hormonal modulation of postnatal expression of intestinal alkaline phosphatase mRNA species and their encoded isoenzymes. (1994) (36)
- Binding of intrinsic factor to ileal brush border membrane in the rat. (1983) (36)
- Role of caloric intake in the weight loss after jejunoileal bypass for obesity (1978) (35)
- Toxicity against gastric cancer cells by combined treatment with 5-fluorouracil and mitomycin c: implication in oxidative stress (2010) (35)
- The two isozymes of rat intestinal alkaline phosphatase are products of two distinct genes. (2000) (34)
- The relationship of psychiatric disorder to gastrointestinal illness. (1986) (34)
- Secretion and distribution of rat intestinal surfactant-like particles after fat feeding. (1994) (34)
- Zinc deficiency in children with environmental enteropathy—development of new strategies: report from an expert workshop1234 (2014) (34)
- Apolipoprotein expression and cellular differentiation in Caco-2 intestinal cells. (1992) (34)
- Absorption and blood/cellular transport of folate and cobalamin: Pharmacokinetic and physiological considerations. (2016) (33)
- Garlic and its potential for prevention of colorectal cancer and other conditions (2009) (33)
- Cellular uptake of cobalamin. (2009) (33)
- A genetic polymorphism in the coding region of the gastric intrinsic factor gene (GIF) is associated with congenital intrinsic factor deficiency (2004) (33)
- Translational approaches for pharmacotherapy development for acute diarrhea. (2012) (32)
- Distribution of soluble and membranous forms of alkaline phosphatase in the small intestine of the rat. (1981) (32)
- The effects of fat feeding on apolipoprotein AI secretion from rat small intestinal epithelium. (1982) (32)
- Induction of rat hepatic and intestinal alkaline phosphatase activity produced by bile from bile duct-ligated animals. (1984) (32)
- Identification of two calcium-binding proteins in human small intestine. A preliminary report. (1972) (31)
- Studies of intestinal transport defect in Hartnup disease. (1971) (31)
- Gastrointestinal symptoms and psychiatric disorders in the general population (1996) (31)
- Differential sensitivity of intestinal brush border enzymes to pancreatic and lysosomal proteases. (1976) (30)
- Appearance of surfactant-like particles in apical medium of Caco-2 cells may occur via tight junctions. (1995) (30)
- Two Rat Intestinal Alkaline Phosphatase Isoforms with Different Carboxyl-terminal Peptides Are Both Membrane-bound by a Glycan Phosphatidylinositol Linkage (*) (1995) (30)
- Developmental regulation of rat intrinsic factor mRNA. (1988) (30)
- Proteolytic processing of the primary translation product of rat intestinal apolipoprotein A-IV mRNA. Comparison with preproapolipoprotein A-I processing. (1982) (30)
- Control of deoxyribonucleic acid synthesis in normal rabbit colonic mucosa. (1975) (30)
- Binding of Pili from UropathogenicEscherichia coli to Membranes Secreted by Human Colonocytes and Enterocytes (1999) (29)
- Human gastric intrinsic factor expression is not restricted to parietal cells. (1996) (29)
- Apical expression of functional asialoglycoprotein receptor in the human intestinal cell line HT-29. (1997) (29)
- Cobalamin release from intrinsic factor and transfer to transcobalamin II within the rat enterocyte. (1989) (29)
- Immunohistochemical survey of cobalamin-binding proteins. (1989) (28)
- Isolation and structural characterization of a cDNA clone encoding rat gastric intrinsic factor. (1988) (28)
- The pharmacodynamics, safety and pharmacokinetics of single doses of the motilin agonist, camicinal, in type 1 diabetes mellitus with slow gastric emptying (2016) (28)
- A novel intracellular pathway for rat intestinal digestive enzymes (alkaline phosphatase and sucrase) via a lamellar particle. (1991) (28)
- Expression of an endogenous asialoglycoprotein receptor in a human intestinal epithelial cell line, Caco-2. (1994) (28)
- Enzymatic properties of rat lactase-phlorizin hydrolase. (1974) (28)
- Hydrophobic interactions of brush border alkaline phosphatases: the role of phosphatidyl inositol. (1987) (27)
- Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells. (1986) (27)
- Protein turnover in intestinal mucosal villus and crypt brush border membranes. (1977) (27)
- Phase separation of rat intestinal brush border membrane proteins using Triton X-114. (1986) (27)
- Gastric intrinsic factor: the gastric and small intestinal stages of cobalamin absorption. a personal journey. (2013) (27)
- Distribution of apolipoproteins A-I and B among intestinal lipoproteins. (1985) (26)
- The effect of carbon tetrachloride on rat-liver lysosomes. (1967) (26)
- The secretion of intestinal alkaline phosphatase (IAP) from the enterocyte. (1994) (26)
- Both tissue and serum phospholipases release rat intestinal alkaline phosphatase. (1990) (26)
- Immunolocalization of alpha-integrin subunits and extracellular matrix components during human colonic organogenesis. (1996) (25)
- The intrinsic factor (IF)-cobalamin receptor binding site is located in the amino-terminal portion of IF. (1992) (24)
- Rat intestinal alkaline phosphatase II messenger RNA is present in duodenal crypt and villus cells. (1997) (24)
- Intractable neurological Wilson's disease treated with orthotopic liver transplantation (1993) (24)
- Glycosylation is not required for ligand or receptor binding by expressed rat intrinsic factor. (1991) (24)
- Principles of Clinical Gastroenterology (2008) (24)
- Monitoring liver safety in drug development: the GSK experience. (2007) (23)
- Equilibrium and Kinetic Analyses of the Interactions between Vitamin B12 Binding Proteins and Cobalamins by Surface Plasmon Resonance (2002) (23)
- Intestinal alkaline phosphatase in patients with chronic renal failure. (1988) (23)
- Characterization of structural and catalytic differences in rat intestinal alkaline phosphatase isozymes (2005) (23)
- Surfactant-like particles mediate tissue-specific functions in epithelial cells. (2001) (23)
- Alimentary hypoglycemia in the absence of gastrointestinal surgery. (1973) (23)
- Metabolism of Glycosylated Human Salivary Amylase: In Vivo Plasma Clearance by Rat Hepatic Endothelial Cells and In Vitro Receptor Mediated Pinocytosis by Rat Macrophages (1984) (22)
- Caco-2 cell transfection by rat intestinal alkaline phosphatase cDNA increases surfactant-like particles. (1992) (22)
- Gastrointestinal epithelial response to injury (1996) (22)
- Isolation and characterization of proteolytically derived ileal receptor for intrinsic factor-cobalamin. (1982) (22)
- Irritable bowel-still more questions than answers. (1981) (22)
- Involvement of intestinal alkaline phosphatase in serum apolipoprotein B-48 level and its association with ABO and secretor blood group types. (2006) (22)
- Noncirrhotic nodular transformation of the liver with portal hypertension: clinical, angiographic, and pathological correlation. (1980) (21)
- Fat feeding stimulates only one of the two mRNAs encoding rat intestinal membranous and secreted alkaline phosphatase. (1987) (21)
- Transfer of cobalamin from intrinsic factor to transcobalamin II. (2001) (21)
- Biosynthesis of apolipoprotein C-III in rat liver and small intestinal mucosa. (1984) (21)
- Long-term follow-up of jejunoileal bypass patients. (1980) (21)
- The minor components of the rat asialoglycoprotein receptor are apically located in neonatal enterocytes. (1991) (21)
- Textbook of gastroenterology: Volume 1 and 2. (1999) (21)
- Expression of intrinsic factor in rat and murine gastric mucosal cell lineages is modified by inflammation. (2000) (20)
- Role of intestinal surfactant-like particles as a potential reservoir of uropathogenic Escherichia coli. (2000) (20)
- Biochemical effects of CCl4 on rat intestinal mucosa (1968) (20)
- Successful maintenance of suckling rat ileum in organ culture. (1979) (20)
- Hartnup disease. Clinical, pathological, and biochemical observations. (1976) (20)
- Nutrition in Pediatrics: Basic Science and Clinical Applications (1998) (20)
- Disorders of intestinal transport of amino acids. (1969) (20)
- Cellular localization and hormonal regulation of pancreatic intrinsic factor secretion in dogs. (1993) (20)
- Isolation and characterization of a cDNA encoding porcine gastric haptocorrin. (1990) (20)
- Vitamin A up-regulates expression of bone-type alkaline phosphatase in rat small intestinal crypt cell line and fetal rat small intestine. (1998) (20)
- Heat shock induces intestinal-type alkaline phosphatase in rat IEC-18 cells. (2003) (19)
- Developmental expression of intestinal surfactant-like particles in rats. (1991) (19)
- Method for determination of specific activity of proteins in polyacrylamide gels. (1970) (19)
- Effect of pancreatic proteases on intestinal lactase activity. (1980) (19)
- Ontogenic and phylogenic studies of intestinal, hepatic, and placental alkaline phosphatases. Evidence that intestinal alkaline phosphatase is a late evolutionary development. (1986) (19)
- Translation of rat intestinal RNA yields two alkaline phosphatases. (1986) (18)
- Inhibition of lactose hydrolysis by dietary sugars. (1971) (18)
- Asialoglycoprotein receptor mRNAs are expressed in most extrahepatic rat tissues during development. (1993) (17)
- In vitro translation of intestinal sucrase-isomaltase and glucoamylase. (1986) (17)
- Dietary fiber decreases colonic epithelial cell proliferation and protein synthetic rates in human subjects. (2006) (17)
- Irritable bowel syndrome: more than abdominal pain and bowel habit abnormalities. (2009) (17)
- Faculty Opinions recommendation of p120-catenin mediates inflammatory responses in the skin. (2006) (17)
- Localization of immunoreactive alkaline phosphatase in the rat small intestine at the light microscopic level by immunocytochemistry (1982) (17)
- How adaptable is the intestine in patients with short-bowel syndrome? (2002) (17)
- The role of lipid peroxidation in the pathogenesis of carbon tetrachloride-induced liver injury. (1968) (17)
- Multidimensionality of symptom complexes in irritable bowel syndrome and other functional gastrointestinal disorders. (2008) (17)
- Identification of pulmonary surfactant that bears intestinal-type and tissue-nonspecific-type alkaline phosphatase in endotoxin-induced rat bronchoalveolar fluid (2001) (17)
- Retinoic Acid Stimulates the Dynamics of Mouse Gastric Epithelial Progenitors (2005) (16)
- Advances in nutrition and gastroenterology: summary of the 1997 A.S.P.E.N. Research Workshop. (1998) (16)
- In vitro expression and secretion of functional mammalian intrinsic factor using recombinant baculovirus. (1992) (16)
- Turnover of intestinal brush-border proteins during postnatal development in rat. (1980) (16)
- Membrane interactions of rat intestinal alkaline phosphatase: role of polar head groups. (1985) (16)
- Intestinal uptake and release of cobalamin complexed with rat intrinsic factor. (1985) (16)
- Cathepsin L mediates intracellular ileal digestion of gastric intrinsic factor. (1995) (16)
- What is new in vitamin B(12)? (2005) (15)
- alpha-Amylase expressed in human liver is encoded by the AMY-2B gene identified in tumorous tissues. (2001) (15)
- Approach to the Patient Requiring Nutritional Supplementation (2009) (15)
- Addison's disease secondary to carcinoma of the breast. (1962) (15)
- Uptake and fate of absorbed amino acids and peptides in the mammalian intestine. (1986) (15)
- Independent biosynthesis of soluble and membrane-bound alkaline phosphatases in the suckling rat ileum. (1981) (14)
- Role of caloric intake in the weight loss after jejunoileal bypass for obesity. (1978) (14)
- Zinc and deficiencies of taste and smell. (1994) (14)
- Functional expression in Pichia pastoris of human and rat intrinsic factor. (2000) (14)
- ISOZYMES OF THE LACTOSE OPERON OF ESCHERICHIA COLI (1968) (14)
- The trophic effects of substrate, insulin, and the route of administration on protein synthesis and the preservation of small bowel mucosal mass in large mammals. (2011) (14)
- Sulfapyridine metabolites in children with inflammatory bowel disease receiving sulfasalazine. (1979) (14)
- Mast cell granules within endothelial cells: a possible signal in the inflammatory process? (1992) (14)
- Vitamin B12, a fascinating micronutrient, which influences human health in the very early and later stages of life. (2013) (14)
- Ileal resection and bile salt metabolism. (1971) (14)
- On β-Galactosidase activity (1969) (13)
- Does total parenteral nutrition-induced intestinal mucosal atrophy occur in humans and can it be affected by enteral supplements? (1996) (13)
- Interaction of receptor for intrinsic factor-cobalamin complex with synthetic and brush-border lipids. (1981) (13)
- Function and stability of human transcobalamin II: role of intramolecular disulfide bonds C98-C291 and C147-C187. (2003) (13)
- The potential use of curcumin in management of chronic disease: too good to be true? (2008) (13)
- Another indication for the use of oral vitamin B-12 supplementation. (2018) (13)
- Cyclic AMP-dependent amino acid uptake in intestine—: The importance of β-adrenergic agonists (1976) (13)
- Quantitation of human intestinal and liver/bone alkaline phosphatase in serum by rocket electroimmunoassay. (1984) (12)
- Regulation of surfactant-like particle secretion by Caco-2 cells. (2001) (12)
- Rat ileal alkaline phosphatase activity and secretion is stimulated by alterations in calcium metabolism. (1989) (11)
- Effect of bile and bile acids on binding of intrinsic factor to cobalamin and intrinsic factor-cobalamin complex to ileal receptor. (1983) (11)
- Complaints of constipation in obsessive-compulsive disorder. (1995) (11)
- Interleukin-1beta enhances retinoic acid-mediated expression of bone-type alkaline phosphatase in rat IEC-6 cells. (2001) (11)
- Surgical therapy for obesity. (1983) (11)
- Secreted intestinal surfactant‐like particles interact with cell membranes and extracellular matrix proteins in rats (2002) (11)
- Differential regulation of mRNAs encoding for rat intestinal alkaline phosphatase. (1990) (11)
- Control of thymidine incorporation in mucosal explants from patients with chronic ulcerative colitis (1980) (11)
- Control of thymidine incorporation in mucosal explants from patients with chronic ulcerative colitis. (1980) (11)
- Hepatobiliary and pancreatic clearance of circulating pancreatic amylase. (1982) (10)
- Functional gastrointestinal disorders. (1983) (10)
- Abundance of surfactant-like particles reflects mucosal integrity in patients with peptic ulcer disease. (1996) (10)
- Irritable bowel syndrome in a psychiatric patient population. (2000) (10)
- CARBOHYDRATES | Digestion, Absorption, and Metabolism (2003) (9)
- A Double-Blind, Randomized Placebo-Controlled Phase II Study of the Pharmacodynamics, Safety/Tolerability, and Pharmacokinetics of Single Doses of the Motilin Agonist GSK962040, in Patients With Type I Diabetes Mellitus (T1DM) and Gastroparesis (2011) (9)
- The effect of hyperglycemic hyperinsulinemia on small-intestinal mucosal protein synthesis in patients after surgical stress. (2006) (9)
- Equilibrium and kinetic analyses of the interactions between vitamin B(12) binding proteins and cobalamins by surface plasmon resonance. (2002) (9)
- Localization of immunoreactive alkaline phosphatase in the rat small intestine at the light microscopic level by immunocytochemistry. (1982) (8)
- Refeeding the malnourished patient. (1999) (8)
- Sulphydryl blocker-induced rat colitis is ameliorated by intravenous injection of antibody to colonic surfactant-like particle. (1999) (8)
- A parable on the dangers of overclassification: can an enterocyte assume immune functions? (1994) (8)
- Vitamins as drugs: the importance of pharmacokinetics in oral dosing (2011) (8)
- Biosynthesis and compartmentalization of rat-intestinal vitamin-D-dependent calcium-binding protein. (1984) (8)
- Gender differences in antacid-induced phosphate deprivation in rats. (1985) (8)
- Metabolism of human isoamylases in the rabbit. (1984) (8)
- Subclinical micronutrient deficiency: a problem in recognition. (2012) (8)
- Fate of circulating isoamylases in the rabbit. (1983) (7)
- A receptor binding site on intrinsic factor is located between amino acids 25-44 and interacts with other parts of the protein. (1997) (7)
- Why should psychotherapy be a useful approach to management of patients with nonulcer dyspepsia? (2000) (7)
- Monosaccharide inhibition of human intestinal lactase. (1971) (7)
- Cobalamin binding proteins and their receptors. (1994) (7)
- Editorial: Pseudomembranous colitis. (1974) (6)
- Separation and isolation of rat and human intestinal beta-galactosidases. (1969) (6)
- Inflammatory bowel disease (ulcerative colitis). (1978) (6)
- Effect of Native and Acetylated Dietary Resistant Starches on Intestinal Fermentative Capacity of Normal and Stunted Children in Southern India (2019) (6)
- Nutritional therapy in inflammatory bowel disease: a historical overview (1997) (6)
- Psychiatric Illness and Inflammatory Bowel Disease (1982) (6)
- Nutrient sensing in the gastrointestinal tract (2010) (6)
- Production of gastric intrinsic factor, transcobalamin, and haptocorrin in opossum kidney cells. (2000) (6)
- Postnatal development of intestinal secretin in rats and guinea pigs. (1982) (6)
- Vitamin B12 absorption and malabsorption. (2022) (6)
- The emerging role of the microbial-gastrointestinal-neural axis (2009) (6)
- MULTIPLE MOLECULAR FORMS OF BETA-GALACTOSIDASE. (1965) (6)
- Intestinal calcium binding protein in uremia (1979) (5)
- Homeodomain proteins and cell phenotype (1997) (5)
- Production of Ectopic Gastric Intrinsic Factor in Gastric Mucosa of Humans with Chronic Gastritis (2011) (5)
- The role of choline on the activity-temperature relationship of brush-border alkaline phosphatase. (1987) (5)
- Clearance of surfactant-like particle proteins from circulation in rats. (1994) (5)
- Use of macro- and micronutrients for nutrition support in inflammatory bowel disease. (1999) (5)
- Effect of tissue non-specific alkaline phosphatase in maintenance of structure of murine colon and stomach. (2000) (5)
- Chronic Infections of the Small Intestine (2009) (5)
- What is new in vitamin B12? (2005) (5)
- Clinical Pattern of Tolvaptan-Associated Liver Injury in Trial Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD): An Analysis of Pivotal Clinical Trials. (2022) (5)
- History and impact of nutritional epidemiology. (2014) (5)
- Interaction of Intestinal Disaccharidases with Phospholipids: Effect of Cholesterol (1985) (4)
- Effect ob broad-spectrum antibiotics on in vitro synthesis of DNA in the rabbit colon. (1978) (4)
- Measurement of intestinal protein synthesis by continuous arterial tracer application: intrinsically difficult problems arising from different protein pools and study techniques. (2011) (4)
- Energy sources for total parenteral nutrition patients: Would sugar suffice? (1984) (4)
- Assessing somatization in urologic chronic pelvic pain syndrome (2019) (4)
- Labelling of intestinal brush border membrane proteins in vivo using diazotised[125I]iodosulfanilic acid. (1981) (4)
- The role of nutritional deficiency in the osteopenia and osteoporosis of gastrointestinal diseases. (2002) (4)
- Nutritional physiology of the alimentary tract (2012) (3)
- Rat intestinal alpha1-antitrypsin secretion is regulated by triacylglycerol feeding. (1999) (3)
- Effect of tissue non‐specific alkaline phosphatase in maintenance of structure of murine colon and stomach (2000) (3)
- Disaccharidase deficiency. (1970) (3)
- Effect of Intralumenal Cation-Exchange Resin on Excretion of Ammonia in Rat Ileum (1981) (3)
- Interleukin-1 b enhances retinoic acid-mediated expression of bone-type alkaline phosphatase in rat IEC-6 cells (2001) (3)
- Intraluminal bioavailability of divalent cations (2013) (3)
- Is irritable bowel syndrome more than just a gastroenterologist’s problem? (2001) (3)
- The Possible Role of Intestinal Surfactantlike Particles in the Absorption of Triacylglycerols in the Rat (2001) (3)
- Expression of functional intrinsic factor using recombinant baculovirus. (1997) (3)
- Liver complications and failure in patients on home parenteral nutrition. (2001) (3)
- Ray E. Clouse, MD, Washington University gastroenterologist, clinical investigator, and educator. (2007) (3)
- Absorption of vitamins and divalent minerals (1989) (3)
- General Nutritional Principles (2009) (2)
- Gut rest versus early feeding after elective abdominal surgery. (1997) (2)
- Isolation of native and proteolytically derived ileal receptor for intrinsic factor-cobalamin. (1986) (2)
- Graphing the gallbladder: Correction (1977) (2)
- In vivo versus cell culture models: the example of lipid biosynthesis in the enterocyte (2008) (2)
- Editorial overview: Why, how, and to which part of the gastrointestinal tract should forced enteral feedings be delivered in patients? (2004) (2)
- Novel in vitro model for studying hepatic ischemia-reperfusion injury using liver cubes. (2012) (2)
- Oral rehydration solutions for adults: An underused resource (1998) (2)
- Faculty Opinions recommendation of Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. (2006) (2)
- Is the Intestine a Portal of Entry for the Serious COVID-19 Complications of Endotoxemia and Thrombosis? (2021) (2)
- Pre-translational, translational, and post-translational mechanisms in adaptation of intestinal proteins. (1990) (2)
- Drug-development concepts as guides for optimizing clinical trials of supplemental zinc for populations at risk of deficiency or diarrhea (2017) (2)
- Comprar Manual of Nutritional Therapeutics 5/e | Beth Taylor RD, CNSD | 9780781768412 | Lippincott Williams & Wilkins (2008) (2)
- Effect of lectins on the cobalamin-protein binding reactions: implications for the tissue uptake of cobalamin. (1990) (2)
- Expression of intestinal-type alkaline phosphatase mRNA in liver of Akp3 knockout mice (2010) (2)
- The centennial year: the development of important ideas during the last 100 years. Nutrition and the gastroenterologist: the last 100 years. (1997) (2)
- Introduction to the series "Best (but Oft-Forgotten) Practices". (2015) (2)
- Another piece to the celiac puzzle. (1987) (2)
- Energy sources for total parenteral nutrition patients: would sugar suffice/. (1984) (2)
- Small intestine. Editorial overview (1991) (1)
- Effect of exchange exocrine pancreatic insufficiency on small intestine in the mouse. (1978) (1)
- Faculty Opinions recommendation of Gut microorganisms, mammalian metabolism and personalized health care. (2005) (1)
- Biochemical effects of CCl-4 on rat intestinal mucosa. (1968) (1)
- Nutrition for the primary care provider (2014) (1)
- Faculty Opinions recommendation of A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation. (2012) (1)
- Fuels For Intestinal Cells (2006) (1)
- Postcrystallization Analysis of the Irreproducibility of the Human Intrinsic Factor-Cobalamin Complex Crystals. (2009) (1)
- Cellular Uptake Behavior of Glycoconjugated and Micellar-Encapsulated Quantum Dots on HeLa Cervical Cancer Cells (2015) (1)
- Nutrition and exercise in obesity management: By J. Storlie and H. A. Jordan. 155 pp., $18.95. Sports Medicine and Health Science, a division of Spectrum Publications Inc., New York, New York, 1984 (1985) (1)
- Beverages in nutrition and health (2004) (1)
- Dog intestinal mucosa contains two vitamin D-stimulated calcium binding proteins (1980) (1)
- Enterocyte protein processing and synthesis (1987) (1)
- A five-year plan of the American Gastroenterological Association. (1991) (1)
- Expression of intrinsic factor in gastric mucosal cell lineages is modified by inflammation (2000) (1)
- Comprar Manual of Nutritional Therapeutics, 6ª Ed. | David H. Alpers | 9781451191875 | Lippincott Williams & Wilkins (2015) (1)
- Cyclic AMP-dependent amino acid uptake in intestine--the importance of beta-adrenergic agonists. (1976) (1)
- A five-year plan of the American Gastroenterological Association: Report of a long-range planning meeting, April 20–22, 1990 (1991) (1)
- The enterocyte as a secretory organ (1994) (1)
- Functional expression of human and rat intrinsic factor in Pichia pastoris (1999) (1)
- Gastric Intrinsic Factor and Cobalamin Absorption (2011) (1)
- Rat intestinal α1-antitrypsin secretion is regulated by triacylglycerol feeding. (1999) (1)
- Psychiatric Evaluation in Inflammatory Bowel Disease- Practical Considerations (1986) (1)
- Su1488 Effect of Native and Acetylated High Amylose Maize Starch on Fecal pH and Short Chain Fatty Acid Concentrations in a Cohort of Children in Southern India (2014) (1)
- Micellar function. (1968) (0)
- Successful maintenance of suckling rat ileum in organ culture (1978) (0)
- Mechanisms of intestinal secretion. Vol. 12, Kroc foundation Series (1980) (0)
- Subject Index, Vol. 46, Supplement 2, 1990 (1990) (0)
- JAMA Peer Reviewers in 2004 (2016) (0)
- Miscellaneous Inflammatory and Structural Disorders of the Colon (2009) (0)
- Faculty Opinions recommendation of A randomized, prospective, comparison study of a mixture of acacia fiber, psyllium fiber, and fructose vs polyethylene glycol 3350 with electrolytes for the treatment of chronic functional constipation in childhood. (2012) (0)
- Su1802 - Histologic Disease Activity Did not Predict Symptoms Among Ulcerative Colitis Patients in Mucosal Remission (2018) (0)
- Faculty Opinions recommendation of Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. (2009) (0)
- Comprar Annual Reports on NMR Spectroscopy Vol. 67 | Graham A. Webb | 9780123750587 | Academic Press (2009) (0)
- Behavior management of obesity (1985) (0)
- Allergic inflammation of joints. Pathogenesis of acute rheumatism. (0)
- Evaluation and treatment of obesity (1985) (0)
- Dog intestinal mucosa contains two vitamin D-stimulating calcium binding proteins. (1980) (0)
- Episodic Memories Among Irritable Bowel Syndrome (IBS) Patients: An Important Aspect of the IBS Symptom Experience (2022) (0)
- JAMA Peer Reviewers in 2016. (2017) (0)
- Faculty Opinions recommendation of Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21). (2010) (0)
- JAMA Peer Reviewers in 2018. (2019) (0)
- Faculty Opinions recommendation of Response of chronic cough to acid-suppressive therapy in patients with gastroesophageal reflux disease. (2012) (0)
- Faculty Opinions recommendation of Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. (2011) (0)
- Book ReviewLecture Notes on Gastroenterology (1969) (0)
- Faculty Opinions recommendation of Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety. (2012) (0)
- Duodenal surfactant-like particles (SLP) are decreased in patients with peptic ulcer disease (1995) (0)
- AGA math: does 1 + 1 = 1? (1991) (0)
- Faculty Opinions recommendation of A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation. (2013) (0)
- Faculty Opinions recommendation of The effect of itopride combined with lansoprazole in patients with laryngopharyngeal reflux disease. (2013) (0)
- F1000Prime recommendation of Efficacy and safety of lesogaberan in gastro-oesophageal reflux disease: a randomised controlled trial. (2012) (0)
- JAMA Peer Reviewers for 2003 (2017) (0)
- Faculty Opinions recommendation of Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study. (2013) (0)
- Do Diverse Mechanisms of Pathogenesis Lead to Final Common Pathways ? (2012) (0)
- If Hoofbeats are not From Horses, It Could be Zebras!! Isolated Hyper-alkaline Phosphatasemia. (2020) (0)
- Vitamin therapy for metabolic diseases. (2003) (0)
- Faculty Opinions recommendation of G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer. (2011) (0)
- Mechanisms of intestinal secretion. Vol. 12, Kroc foundation Series: Edited by Henry J. Binder. 319 pp., $28.00 Alan R. Liss, Inc., New York, New York, 1979 (1980) (0)
- Faculty Opinions recommendation of Quantification of the effect of energy imbalance on bodyweight. (2011) (0)
- Atlas of gastroenterology : self-assessment guide (1997) (0)
- Synergistic effects of retinoic acid and IL-1β on expression of the bone-type alkaline phosphatase and retinoid receptors in small intestinal epithelial cells (1998) (0)
- Faculty of 1000 evaluation for Induction of intestinal Th17 cells by segmented filamentous bacteria. (2015) (0)
- On beta-galactosidase activity. (1969) (0)
- Translation of Motilin and Ghrelin Receptor Agonists into Drugs for Gastrointestinal Disorders (2011) (0)
- Handbook of Nutrition and Food (2003) (0)
- Faculty Opinions recommendation of Randomised clinical trial: alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS. (2012) (0)
- Reviewers of Manuscripts and Books (1976) (0)
- 636 MECHANISMS FOR SEX DIFFERENCES IN ANTACID-INDUCED PHOSPHATE DEPLETION (1981) (0)
- Faculty Opinions recommendation of Partial symptom-response to proton pump inhibitors in patients with non-erosive reflux disease or reflux oesophagitis - a post hoc analysis of 5796 patients. (2012) (0)
- Surfactant-like particles serve multiple, tissue-specific functions. (2000) (0)
- Cloning of a cDNA encoding rat intestinal-fatty acid binding protein ( cDNA cloning / primary and secondary protein structure analyses ) (0)
- The significance and future prospects of study of the small intestine. (1994) (0)
- Some new characteristics of urinary Tamm-horsfall glycoprotein-its possible use as a prostate cancer biomarker (2018) (0)
- The enterocyte as a secretory organ : The role of intestinal alkaline phosphatase in triacylglycerol absorption.:The role of intestinal alkaline phosphatase in triacylglycerol absorption (1994) (0)
- W1548 Role of Lysophosphatidylcholine in Intestinal Alkaline Phosphatase Release and Restoration (2009) (0)
- Effect of secreted proteases derived from intestinal anaerobes on human brush border sucrase (1978) (0)
- Expression of intrinsic factor and pepsinogen in the rat stomach identifies a subset of parietal cells. (1998) (0)
- Surgery for Morbid Obesity (1983) (0)
- Faculty Opinions recommendation of SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. (2007) (0)
- Faculty Opinions recommendation of Effect of gender on prevalence of irritable bowel syndrome in the community: systematic review and meta-analysis. (2012) (0)
- Crohn's disease and psychiatric illness (1984) (0)
- Dr. North and Associates Reply (1991) (0)
- 634 EFFECT OF INTRALUMENAL CATION-EXCHANGE RESIN ON EXCRETION OF AMMONIA IN RAT ILEUM (1981) (0)
- Is irritable bowel syndrome more than just a gastroenterologist's problem? (2001) (0)
- Faculty Opinions recommendation of Systematic review: Coca-Cola can effectively dissolve gastric phytobezoars as a first-line treatment. (2013) (0)
- The role of psychiatric assessment in the management of functional bowel disease. (1984) (0)
- Faculty Opinions recommendation of Bifidobacteria can protect from enteropathogenic infection through production of acetate. (2011) (0)
- Comments on psychiatric aspects of ulcerative colitis. (1991) (0)
- AGA Presidential address: 1991: AGA math: Does 1 + 1=1? (1991) (0)
- Undergraduate teaching project of the American gastroenterological Association: a pathophysiology resource. (1991) (0)
- Faculty Opinions recommendation of Concomitant symptoms itemized in the Reflux Disease Questionnaire are associated with attenuated heartburn response to acid suppression. (2012) (0)
- Gene induction in intestinal epithelial cells in response to injury (1998) (0)
- Faculty Opinions recommendation of A randomised controlled study of the effect of cholinesterase inhibition on colon function in patients with diabetes mellitus and constipation. (2012) (0)
- ‘Disease management’ in chronic medical conditions (2003) (0)
- 22 'Disease management' in chronic medical conditions (0)
- Faculty Opinions recommendation of The emergence of geometric order in proliferating metazoan epithelia. (2006) (0)
- Vitamins and prevention of cardiovascular disease and cancer: should we give supplements? (2007) (0)
- Faculty Opinions recommendation of Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C. (2008) (0)
- Disease Management in Chronic Medical Conditions and its Relevance to Inflammatory Bowel Disease (2010) (0)
- Health Outcomes Associated with Vegetarian Diets: An Umbrella Review of Systematic Reviews and Meta-Analyses (2019) (0)
- Dietary Fat Feeding Alters Lipid Peroxidation in Surfactant-like Particles Secreted by Rat Small Intestine (2009) (0)
- Pepsin binds to Helicobacter pylori and inhibits its growth in vitro (1998) (0)
- Nutrition and exercise in obesity management (1985) (0)
- Faculty Opinions recommendation of The crystal structure of a voltage-gated sodium channel. (2011) (0)
- Faculty Opinions recommendation of Transcutaneous electrical tibial nerve stimulation in the treatment of fecal incontinence: a randomized trial (CONSORT 1a). (2012) (0)
- Faculty Opinions recommendation of Autophagy-dependent viral recognition by plasmacytoid dendritic cells. (2007) (0)
- Thank you Reviewers (2003) (0)
- History and Impact of Nutritional Epidemiology 1 – 3 (2014) (0)
- Faculty Opinions recommendation of Hereditary juvenile cobalamin deficiency caused by mutations in the intrinsic factor gene. (2005) (0)
- Manual of nutrition therapeutics (2013) (0)
- Reviewers for DDS—Thank you (2005) (0)
- A heat shock cognate protein 70 interacts with cathepsin J and regulates the lysosomal proteolysis in human adenocarcinoma Caco-2 cells (2000) (0)
- Centennial report to American Gastroenterological Association members. (1996) (0)
- Evaluation and treatment of obesity: By J. Storlie and H. A. Jordan. 159 pp., $18.95. Sports Medicine and Health Science, a division of Spectrum Publications Inc., New York, New York, 1984 (1985) (0)
- Faculty Opinions recommendation of Oral zinc for treating diarrhoea in children. (2013) (0)
- Current status of surgery for morbid obesity. (1980) (0)
- Faculty Opinions recommendation of Host range and cellular tropism of the human exogenous gammaretrovirus XMRV. (2010) (0)
- Adaptive changes in protein synthesis in gastrointestinal mucosa (1992) (0)
- Blood Group Antigenicity of Purified Human Intestinal (2002) (0)
- Ray E. Clouse, M.D. (2007) (0)
- Reviewer Acknowledgment (2012) (0)
- The elusive causes of relapse in ulcerative colitis. (2004) (0)
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