David J. Blackbourn
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Why Is David J. Blackbourn Influential?
(Suggest an Edit or Addition)According to Wikipedia, David John Blackbourn PhD FRSB is currently Professor of Virology and Director of the Institute of Medical Sciences at the University of Aberdeen. His research interests emphasise virus understanding how viruses have evolved to manipulate immune responses. Having previously been Head of the School of Biosciences and Medicine for 8 years. He is also a co-founder of Ducentis BioTherapeutics to produce a novel anti-inflammatory therapeutic drug and until September 2022, was non-executive board member. Blackbourn is an Editor-in-Chief of FEMS Microbiology Reviews.
David J. Blackbourn's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients (1996) (556)
- Herpes-like sequences in HIV-infected and uninfected Kaposi's sarcoma patients. (1995) (545)
- CD8+ T cells suppress human immunodeficiency virus replication by inhibiting viral transcription. (1995) (259)
- Limited Transmission of Kaposi’s Sarcoma-Associated Herpesvirus in Cultured Cells (1998) (252)
- Infectious human herpesvirus 8 in a healthy North American blood donor (1997) (184)
- Kaposi's sarcoma-associated herpesvirus immune modulation: an overview. (2006) (151)
- The Red-Water Ciliate Mesodinium rubrum and its "Incomplete Symbionts": A Review Including New Ultrastructural Observations (1971) (147)
- Human herpesvirus 8 detection in nasal secretions and saliva. (1998) (134)
- The Evolutionarily Conserved Kaposi's Sarcoma-associated Herpesvirus ORF57 Protein Interacts with REF Protein and Acts as an RNA Export Factor* (2004) (115)
- The restricted cellular host range of human herpesvirus 8 (2000) (109)
- Inhibition of Interferon Signaling by the Kaposi's Sarcoma-Associated Herpesvirus Full-Length Viral Interferon Regulatory Factor 2 Protein (2006) (109)
- The relevance of complement to virus biology (2004) (108)
- Suppression of HIV replication by lymphoid tissue CD8+ cells correlates with the clinical state of HIV-infected individuals. (1996) (99)
- Complement Regulation by Kaposi's Sarcoma-Associated Herpesvirus ORF4 Protein (2003) (97)
- Spatial covariation in survival rates of Northeast Pacific pink salmon (Oncorhynchus gorbuscha) (2001) (95)
- Modulation of the immune system by Kaposi's sarcoma-associated herpesvirus. (2009) (95)
- Kaposi's Sarcoma-Associated Herpesvirus Promotes Angiogenesis by Inducing Angiopoietin-2 Expression via AP-1 and Ets1 (2007) (90)
- Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression. (2017) (90)
- Transcription mapping of human herpesvirus 8 genes encoding viral interferon regulatory factors. (2003) (89)
- Foreign Organelle Retention by Ciliates (1973) (80)
- Functional Activity of the Complement Regulator Encoded by Kaposi's Sarcoma-associated Herpesvirus* (2003) (80)
- An analysis of the function and expression of D6 on lymphatic endothelial cells. (2013) (76)
- Identification of a Lysosomal Pathway Regulating Degradation of the Bone Morphogenetic Protein Receptor Type II* (2010) (72)
- Increased human herpesvirus 8 seroprevalence in young homosexual men who have multiple sex contacts with different partners. (1999) (69)
- Spatial covariation in survival rates of northeast pacific chum salmon (2002) (69)
- Merkel Cell Polyomavirus Small T Antigen Mediates Microtubule Destabilization To Promote Cell Motility and Migration (2014) (64)
- CD8 cell noncytotoxic antiviral activity in human immunodeficiency virus-infected and -uninfected children. (1998) (59)
- Functional co-operation between the Kaposi's sarcoma-associated herpesvirus ORF57 and ORF50 regulatory proteins. (2004) (59)
- Infectious agents in human cancers: lessons in immunity and immunomodulation from gammaherpesviruses EBV and KSHV. (2011) (57)
- Human herpesvirus 8 in semen and prostate. (1997) (57)
- Dissecting the Regions of Virion-Associated Kaposi's Sarcoma-Associated Herpesvirus Complement Control Protein Required for Complement Regulation and Cell Binding (2006) (56)
- Ultrastructure of the Chloroplasts and Associated Structures within the Marine Ciliate Mesodinium rubrum (Lohmann) (1969) (54)
- An Interaction between KSHV ORF57 and UIF Provides mRNA-Adaptor Redundancy in Herpesvirus Intronless mRNA Export (2011) (53)
- Effects of in vivo and in vitro administration of morphine sulfate upon rhesus macaque polymorphonuclear cell phagocytosis and chemotaxis. (1992) (53)
- Identification of Caspase-mediated Decay of Interferon Regulatory Factor-3, Exploited by a Kaposi Sarcoma-associated Herpesvirus Immunoregulatory Protein* (2009) (51)
- The Viral Interferon Regulatory Factors of Kaposi's Sarcoma-Associated Herpesvirus Differ in Their Inhibition of Interferon Activation Mediated by Toll-Like Receptor 3 (2012) (51)
- Suppression of HIV replication by CD8+ cell clones derived from HIV-infected and uninfected individuals. (1994) (47)
- CD8+ cells from HIV‐2‐infected baboons control HIV replication (1997) (45)
- The feeding biology of tintinnid protozoa and some other inshore microzooplankton (1974) (45)
- The Kaposi's Sarcoma-associated Herpesvirus Complement Control Protein Mimics Human Molecular Mechanisms for Inhibition of the Complement System* (2004) (43)
- Inhibition of neutrophil function by the Kaposi's sarcoma-associated herpesvirus vOX2 protein (2005) (42)
- Induction of human herpesvirus-8 gene expression by recombinant interferon gamma. (2000) (41)
- Activation of DNA Damage Response Pathways during Lytic Replication of KSHV (2015) (40)
- Suppression of Antigen-Specific T Cell Responses by the Kaposi's Sarcoma-Associated Herpesvirus Viral OX2 Protein and Its Cellular Orthologue, CD200 (2012) (38)
- Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Inhibits Neutrophil Recruitment through an Interleukin-6-Dependent Mechanism: a New Paradigm for Viral Immune Evasion (2011) (38)
- Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor-2 inhibits type 1 interferon signalling by targeting interferon-stimulated gene factor-3. (2011) (37)
- Inflammatory Cytokines Inhibit Kaposi's Sarcoma-Associated Herpesvirus Lytic Gene Transcription in In Vitro-Infected Endothelial Cells (2004) (34)
- Vitamin D status, body mass index, ethnicity and COVID-19: Initial analysis of the first-reported UK Biobank COVID-19 positive cases (n 580) compared with negative controls (n 723) (2020) (33)
- Superinfection with human immunodeficiency virus type 2 can reactivate virus production in baboons but is contained by a CD8 T cell antiviral response. (1997) (27)
- Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation (2017) (24)
- Characterization of the Complement Inhibitory Function of Rhesus Rhadinovirus Complement Control Protein (RCP)* (2009) (24)
- Kaposi's Sarcoma-Associated Herpesvirus Inhibits Expression and Function of Endothelial Cell Major Histocompatibility Complex Class II via Suppressor of Cytokine Signaling 3 (2012) (22)
- Vitamin D supplement use and associated demographic, dietary and lifestyle factors in 8024 South Asians aged 40–69 years: analysis of the UK Biobank cohort (2018) (21)
- Functional analysis of Kaposi's sarcoma–associated herpesvirus vFLIP expression reveals a new mode of IRES-mediated translation (2014) (21)
- Suppression of human immunodeficiency virus type 1 replication by a soluble factor produced by CD8+ lymphocytes from HIV-2-infected baboons. (1999) (20)
- Human immunodeficiency virus-2 infection in baboons is an animal model for human immunodeficiency virus pathogenesis in humans. (1998) (20)
- Molecular Characterization of the Rhesus Rhadinovirus (RRV) ORF4 Gene and the RRV Complement Control Protein It Encodes (2007) (19)
- Transient virus infection and pathogenesis of a new HIV type 2 isolate, UC12, in baboons. (1998) (19)
- Adenovirus E1A interacts directly with, and regulates the level of expression of, the immunoproteasome component MECL1. (2011) (18)
- Anti-HHV-8/KSHV antibodies in infected individuals inhibit infection in vitro (2004) (17)
- Very high prevalence of 25-hydroxyvitamin D deficiency in 6433 UK South Asian adults: analysis of the UK Biobank Cohort (2020) (17)
- Human CD8+ cell non-cytolytic anti-HIV activity mediated by a novel cytokine. (1994) (16)
- Molecular cloning of the human immunodeficiency virus subtype 2 strain HIV-2UC2. (1996) (16)
- Inflammatory Cell Distribution in Primary Merkel Cell Carcinoma (2014) (16)
- Risk factors in the development of Kaposi's sarcoma. (2008) (16)
- Pigments of the ciliate, mesodinium rubrum (Lohmann) (1968) (16)
- Detection of simian immunodeficiency virus RNA from infected rhesus macaques by the polymerase chain reaction. (1992) (15)
- Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K15 gene of Kaposi's sarcoma-associated herpesvirus. (2009) (13)
- Inhibition of simian immunodeficiency virus (SIV) replication by CD8 + cells of SIV‐infected rhesus macaques: Implications for immunopathogenesis (1994) (13)
- KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection. (2020) (13)
- Immune responses in baboons vaccinated with HIV‐2 genetic expression libraries (2002) (9)
- Aflatoxin B1 inhibits the type 1 interferon response pathway via STAT1 suggesting another mechanism of hepatocellular carcinoma (2017) (8)
- HIV Tat-mediated transcriptional regulation of proteasome protein cleavage specificity. (2006) (7)
- Infection and transmission dynamics of rKSHV.219 in primary endothelial cells (2013) (7)
- Separation of decay‐accelerating and cofactor functional activities of Kaposi's sarcoma‐associated herpesvirus complement control protein using monoclonal antibodies (2007) (7)
- Vitamin D concentration, body mass index, ethnicity and SARS-CoV-2/COVID-19: initial analysis of the first- reported UK Biobank Cohort positive cases (n 1474) compared with negative controls (n 4643) (2020) (6)
- Innate barriers to viral infection. (2012) (5)
- Structural properties of a viral orthologue of cellular CD200 protein: KSHV vOX2. (2015) (5)
- Emergence of antigenic variants of simian immunodeficiency virus (SIVmac) in a seronegative macaque after SIVmac239 infection. (1994) (5)
- Sea surface temperature and the subsequent freshwater survival rate of some salmon stocks: a surprising link between the climate of land and sea (1993) (3)
- Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K 15 gene of Kaposi ’ s sarcoma-associated herpesvirus (2009) (3)
- Susceptibility of peripheral blood mononuclear cells from gorillas, orangutans and baboons to diverse HIV isolates. (1996) (3)
- Bone health and dietary, lifestyle and anthropometric factors in urban dwelling South Asians (n 2438): data from the UK Biobank cohort (2017) (1)
- Merkel cell polyomavirus small T antigen drives cell motility via Rho-GTPase-induced filopodia formation (2017) (1)
- Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort (2021) (1)
- Evaluation of anti-SIV potential of anti-neoplastic anthracyclines. (1992) (1)
- Characterization of the complement inhibitory function of Rhesus rhadinovirus (2008) (0)
- Infection of endothelial cells with Kaposi's sarcoma-associated herpesvirus selectively inhibits recruitment of flowing neutrophils in an inflammatory model (2009) (0)
- HOST RANGE STUDIES OF HUMAN HERPESVIRUS 8 (HHV8): 73 (1997) (0)
- Leucocyte trafficking (PP-028) (2010) (0)
- A simple method to distinguish between simian immunodeficiency virus isolates by restriction analysis of PCR products. (1993) (0)
- The effect of vitamin D3 supplementation on Interleukin-6 concentrations in healthy South Asian and Caucasian women: preliminary analysis of the D2-D3 study (2018) (0)
- Membrane-Associated and Secreted Forms of the Rhesus Macaque Rhadinovirus-Encoded CD200 Homologue and Cellular CD200 Demonstrate Differential Effects on Rhesus Macaque CD200 Receptor Signaling and Regulation of Myeloid Cell Activation (2020) (0)
- Opposite Effects of Sea-Surface Temperature on Survival Rates of Pacific Salmon from Northern and Southern Areas (2006) (0)
- Molecular details of the complement regulatory and cell attaching functions of KCP (2007) (0)
- IDENTIFICATION OF CELLULAR AND VIRAL GENES POTENTIALLY INVOLVED IN HUMAN HERPESVIRUS (HHV)-8 PATHOGENESIS. (1998) (0)
- Kaposi’s Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Inhibits Neutrophil Recruitment through an Interleukin-6-Dependent Mechanism: a New Paradigm for Viral Immune Evasion (cid:1) (2011) (0)
- Aflatoxin B1 inhibits the type 1 interferon response pathway via STAT1 suggesting another mechanism of hepatocellular carcinoma (2017) (0)
- Ethnic differences in vitamin D and Interleukin-6 levels in healthy South Asian and Caucasian women revealed by the D2-D3 study (2017) (0)
- Th1/Th2 cytokines in AIDS: sorting out the confusion (1994) (0)
- Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL) (2023) (0)
- Very high prevalence of vitamin D deficiency in South Asian adults (n 6433) in the UK Biobank: urgent action required (2020) (0)
- Socio-economic deprivation correlates with lower 25-hydroxyvitamin D concentration: analysis of n 447,766 individuals from the UK Biobank cohort (2022) (0)
- Vitamin D supplementation usage and its predictors in UK South Asian adults (n 8024) aged 40–69 years: preliminary analysis of data from the UK Biobank (2017) (0)
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