David Jack
#51,311
Most Influential Person Now
British pharmacologist
David Jack 's AcademicInfluence.com Rankings
David Jack medical Degrees
Medical
#1224
World Rank
#1543
Historical Rank
Pharmacology
#448
World Rank
#503
Historical Rank
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Medical
David Jack 's Degrees
- Bachelors Pharmacology University of Oxford
- PhD Pharmacology University of Oxford
Why Is David Jack Influential?
(Suggest an Edit or Addition)According to Wikipedia, Sir David Jack was a Scottish pharmacologist and medicinal chemist who specialised in the development of drugs for treating asthma. He was head of research and development at Glaxo from 1978 until 1987.
David Jack 's Published Works
Published Works
- Handbook of Clinical Pharmacokinetic Data (1992) (80)
- The effect of age on the pharmacokinetics of metoprolol and its metabolites. (1981) (69)
- The determination of hydralazine in plasma by gas-liquid chromatography. (1975) (65)
- The influence of food on the absorption of diclofenac after single and multiple oral doses (2004) (48)
- Determination of low levels of Oxprenolol in blood or plasma by gas-liquid chromatography (1974) (48)
- Metoprolol pharmacokinetics and the oral contraceptive pill. (1982) (43)
- Ranitidine and cimetidine; drug interactions with single dose and steady-state nifedipine administration. (1987) (43)
- A study of the effect of aspirin on the pharmacokinetics of oral and intravenous diclofenac sodium (1980) (34)
- Pharmacokinetics of iodochlorhydroxyquin in man. (1973) (33)
- Determination of total monohydroxylated metabolites of diclofenac in urine by electron-capture gas-liquid chromatography. (1980) (33)
- The effect of hydralazine on the pharmacokinetics of three different beta adrenoceptor antagonists: metoprolol, nadolol, and acebutolol. (1982) (26)
- Lack of a pharmacokinetic interaction between nifedipine and the beta-adrenoceptor blockers metoprolol and atenolol. (1984) (24)
- Keep taking the tomatoes--the exciting world of nutraceuticals. (1995) (23)
- Detection of some antihypertensive drugs and their metabolites in urine by thin-layer chromatography. Five commonly used beta blockers and hydralazine. (1980) (23)
- Comparison of the pharmacodynamic and pharmacokinetic profiles of single and multiple doses of a commercial slow-release metoprolol formulation with a new Oros delivery system. (1982) (22)
- Beta-adrenoceptor blocker pharmacokinetics and the oral contraceptive pill. (1984) (21)
- THE INFLUENCE OF BETA‐ADRENOCEPTOR BLOCKADE ON THE LIPOLYTIC RESPONSE TO EXERCISE (1987) (21)
- Lack of evidence for polymorphism in metoprolol metabolism. (1983) (20)
- Detection of some antihypertensive drugs and their metabolites in urine by thin-layer chromatography: II. A further five beta blockers and dihydralazine. (1980) (20)
- Variability of beta-blocker pharmacokinetics in young volunteers (2004) (19)
- Pharmacokinetics of cephradine given intravenously with and without probenecid. (1981) (18)
- The intra- and inter-subject variability of Nifedipine pharmacokinetics in young volunteers (2004) (18)
- Pharmacokinetics and pharmacodynamics of isradipine (PN 200-110) in young and elderly patients (1988) (17)
- The pharmacokinetics of diclofenac sodium in patients with active rheumatoid disease (2004) (17)
- Type II diabetes: tips for managing your older patients. (1996) (17)
- Determination of timolol in plasma and breast milk using high-performance liquid chromatography with electrochemical detection. (1984) (17)
- The Influence of Age on the Pharmacokinetics of Nitrendipine (1987) (16)
- RECENT ADVANCES IN PHARMACEUTICAL CHEMISTRY:THE 4‐QUINOLONE ANTIBIOTICS (1986) (16)
- The effect of food and alcohol on the pharmacokinetics of acebutolol and its metabolite, diacetolol. (1984) (16)
- Determination of metoprolol metabolites in plasma and urine by electron-capture gas--liquid chromatography. (1980) (15)
- Lack of effect of liver disease on the pharmacokinetics of acebutolol and diacetolol: a single dose study. (1985) (14)
- A multiple dose comparative study of the pharmacodynamic and pharmacokinetic behaviour of polymer-matrix and Oros dosage forms of oxprenolol in healthy volunteers. (1985) (12)
- Pharmacokinetic interactions between felodipine and metoprolol (2004) (12)
- The influence of food on the absorption of diclofenac as determined by the urinary excretion of the unchanged drug and its major metabolites during chronic administration (2004) (11)
- The effects of ranitidine and cimetidine on the pharmacokinetics and pharmacodynamics of metoprolol (1988) (10)
- Evaluation of simple method to check compliance with antihypertensive drug therapy. (1980) (10)
- Drug-resistant bacteria: responding to the infectious disease crisis. (1996) (9)
- Inter- and intra-subject variability of nitrendipine and the effects of food (2004) (9)
- The penetration of acebutolol and its major metabolite, diacetolol, into human cerebrospinal fluid and saliva. (1981) (9)
- Campylobacter infections, Guillain-Barré syndrome, and parenteral gangliosides (1991) (8)
- FACTORS CONTRIBUTING TO VARIABILITY IN DRUG PHARMACOKINETICS. III. METABOLISM (1985) (7)
- Measurement of the distribution coefficients of several classes of drug using reversed-phase thin-layer chromatography. (1988) (5)
- Metabolism and excretion of guanoxan in man (1971) (5)
- The metabolism and excretion of guanoxan in man. (1972) (5)
- [Anticoagulant efficacy of Sintrom and blood concentration of Ludiomil on simultaneous administration of the two preparations]. (1975) (4)
- Statistical analysis of polymorphic drug metabolism data using the Rosin Rammler Sperling Weibull distribution (2004) (4)
- THE DISAPPEARING HYPERTENSIVES (1980) (4)
- Determination of prenalterol in plasma and urine by liquid chromatography with electrochemical detection. (1984) (4)
- A surgical cut into computers. (1986) (4)
- Give a drug a bad name. (1991) (4)
- Separate and combined effects of nadolol and nifedipine on the cardiac response to exercise (2004) (4)
- Gradient elution in column liquid chromatography: Theory and practice (1985) (3)
- Live dangerously — eat something (1996) (3)
- How much drug in the tablet? (1991) (3)
- Reproducibility of oxprenolol plasma concentrations in young female volunteers following oral administration of an oxprenolol Oros dosage form. (1985) (3)
- DRUG REACTIONS AND THE POOR METABOLISER (1983) (3)
- THE PHARMACOKINETICS OF OXPRENOLOL FOLLOWING ORAL AND RECTAL DOSING–A COMPARISON OF DELIVERY SYSTEMS AND ROUTES OF ADMINISTRATION (1987) (3)
- Measurement of dihydralazine by high-performance liquid chromatography (1979) (3)
- Drug Analysis by Gas Chromatography (1985) (3)
- Pharmacokinetic data on antiepileptic agents (1992) (2)
- Cost of treating HIV disease and associated infections (1997) (2)
- BETA-BLOCKERS AND DEBRISOQUINE METABOLISER STATUS (1982) (2)
- The pharmacokinetics of oral and intravenous prenalterol in young, healthy volunteers. (1986) (2)
- Twelve hour (trough) plasma nifedipine concentrations during chronic treatment with nifedipine retard (2004) (2)
- Comments to the article “Improved gas chromatographic method of determining diclofenac in plasma” (1981) (2)
- Variability of plasma drug concentrations: Some observations (2004) (2)
- Women in new drug trials. (1982) (2)
- Unravelling mechanisms of disease and treatment in psoriasis (1995) (2)
- THE THERAPEUTIC ROLE OF GANGLIOSIDES (1990) (2)
- Antibodies fight fat cells in humans as well as in animals? (1997) (2)
- Pharmacokinetic data on antidiabetic agents (1992) (1)
- Quinolones: Proceedings of an international telesymposium, edited by P. B. Fernandes, J. R. Prous Science Publishers, Barcelona, 1990. (1991) (1)
- Dictionary of drugs: Chemical data, structures and bibliographies, edited by J. Elks and C. R. Ganellin. Chapman and Hall, 1990, ISBN 0412273004. (1991) (1)
- Pharmacokinetic data on calcium antagonists and peripheral vasodilators (1992) (1)
- Herpes simplex virus and Alzheimer's disease. (1996) (1)
- Dastardly deeds at Dorpat. (1984) (1)
- Pharmacokinetic data on anxiolytic and hypnotic agents (1992) (1)
- Spider farming, spider venom and neurexins. (1996) (1)
- Pharmacokinetic data on quinolone antibiotics (1992) (1)
- Pharmacokinetic data on respiratory agents (1992) (1)
- UpdateCardiovascular trials update (1996) (1)
- Tuberculosis therapy and enzyme induction in man. (1980) (1)
- Pharmacokinetic data on antiprotozoal agents (1992) (1)
- The future of migraine treatment beyond sumatriptan (1994) (1)
- Bee-glue reveals anti-inflammatory properties plus... (1996) (1)
- Hard data on stronger bones (1999) (1)
- Book reviews (1984) (0)
- HIV vaccine research continues despite setbacks (1996) (0)
- Pharmacokinetic data on tetracyclines, aminoglycosides and related agents (1992) (0)
- New trials support use of abciximab in PTCA (1996) (0)
- New results support role of amifostine in cytoprotection (1993) (0)
- Pharmacokinetic data on antiviral agents (1992) (0)
- Macrolides in profile at the 1st European Congress of Chemotherapy (1996) (0)
- Apomorphine: stiff competition for 'Viagra' (2001) (0)
- Pharmacokinetic data on analgesic and antimigraine agents (1992) (0)
- Pharmacokinetic data on cephalosporins and other anti-infective agents (1992) (0)
- Death due to congenital abnormality of the coronary arteries and to exposure to cold. (1959) (0)
- Interim results show HOT study is on target (1996) (0)
- Advances in tissue repair. (1995) (0)
- Pharmacokinetic data on anticoagulant,antiplatelet and lipid-lowering agents (1992) (0)
- Measurement of Iodochlorhydroxyquin/Clioquinol (1978) (0)
- Book reviews (1985) (0)
- Metalloproteinase inhibitors: sparks of potential in inflammatory disease (1995) (0)
- Book reviews (1986) (0)
- Voriconazole: a natural successor to fluconazole? (1998) (0)
- Necrotising fasciitis - a real concern or just a case of media hype? (1994) (0)
- Sensitive skin - steps towards controlling reactions (1995) (0)
- Pharmacokinetic data on antispasmodic, antiulcer and antidiarrhoea agents (1992) (0)
- THE EFFECTS OF DRUGS AND DISEASE ON LIVER FUNCTION TESTS (1980) (0)
- Pharmacokinetic data on antiarrhythmic agents (1992) (0)
- New trends in osteoarthritis research (1995) (0)
- Vigabatrin - generating interest in epilepsy research (1992) (0)
- Pharmacokineic data on anthelmintic agents (1992) (0)
- Book Reviews (2003) (0)
- Traditional Chinese medicine yields a kinase inhibitor for use in cancer and HIV. (1996) (0)
- Funding the prescription of DMARDs in the UK − a view from the front line (2001) (0)
- Pharmacokinetic data on cardiovascular agents (1992) (0)
- Pharmacokinetic data on miscellaneous agents (1992) (0)
- Interfering with efflux pumps for increased antifungal effects? (1998) (0)
- Book reviews (1986) (0)
- Pharmacokinetic data on antiparkinson and related agents (1992) (0)
- Lamotrigine: another promising agent for epilepsy (1992) (0)
- TDM could hold the key to more effective HIV treatment (2000) (0)
- Pharmacokinetic data on antipsychotic agents (1992) (0)
- Pharmacokinetic data on beta-adrenoceptor antagonists (1992) (0)
- Pharmacokinetic data on antituberculous and antileprotic agents (1992) (0)
- Outcome measures in RA - reducing the ‘signal-to-noise’ ratio (1995) (0)
- Somatoform Disorder Patients in Family Practice (1998) (0)
- IMPROVING EMOTIONAL AND SOCIAL INTELLIGENCE AMONG SECONDARY SCHOOL STUDENTS: THE ROLE OF TRAINING (2020) (0)
- Potential applications of new antioxidants (1994) (0)
- Medicines from nature - bioprospecting, biopiracy and benefit sharing (1998) (0)
- Surrogate markers accelerate antiviral approval (1994) (0)
- Attitudes to cannabis on a high? (1997) (0)
- MERIT-HF trial to investigate role of metoprolol in heart failure (1996) (0)
- Latest drug research in rheumatology (1995) (0)
- GnRH agonists and antagonists square up for a fight (1999) (0)
- Pharmacokinetic data on antiinflammatory agents (1992) (0)
- Unique post-doc system at SUNBOR (1997) (0)
- Pharmacokinetic data on antihypertensive agents (1992) (0)
- Swedish scientist honoured for Turbohaler (1996) (0)
- Antihypertensive agents PROGRESS in stroke (2001) (0)
- Pharmacokinetic data on cerebral vasodilators and sympathomimetics (1992) (0)
- Outbreak of interior poliomyelitis in H. M. S. Jamaica. (1946) (0)
- New Alzheimer's model from Japan (1996) (0)
- The earliest demonstration of the placental passage of morphine? (1982) (0)
- Pharmacokinetic data on antineoplastic and immunosuppressant agents (1992) (0)
- An Evaluation of the Immunological Risk of Ganglioside (‘Cronassial’) Injections (1991) (0)
- Pharmacokinetic data on corticosteroids (1992) (0)
- Pharmacokinetic data on penicillins (1992) (0)
- Furberg goes over the top on calcium channel antagonists (1996) (0)
- Dioscoride Vitali and Carlo Erba - two key figures in nineteenth century Italian pharmacy. (1993) (0)
- A good read (1981) (0)
- Safer NSAIDs? Selective COX-2 inhibitors may be the answer (1995) (0)
- Latest data on the use of angiotensin II antagonists in hypertension (1996) (0)
- Scots search for slimmers' holy grail (1996) (0)
- Pharmacokinetic data on hormones and their antagonists (1992) (0)
- Senate FDA reform bill--good news for the pharmaceutical industry? (1995) (0)
- Pharmacokinetic data on thyroid and antithyroid agents (1992) (0)
- New biomaterials aid tissue repair (1995) (0)
- Pharmacokinetic data on antinausea and antivertigo agents (1992) (0)
- Reducing costs by reducing lipid levels in CHD (1996) (0)
- Drug companies on the net (1996) (0)
- NEW SERIES:HOST FACTORS AFFECTING DRUG DISPOSITION (1984) (0)
- Pharmacokinetic data on anaesthetics and neuromuscular blockers (1992) (0)
- Reducing costs by reducing lipid levels in CHD (1996) (0)
- Book reviews (1984) (0)
- Update on current treatments in dermatology (1995) (0)
- Book reviews (1983) (0)
- Book reviews (1983) (0)
- HOW MUCH DRUG IN THE TABLET ? AUTHOR'S REPLY (1991) (0)
- Bioanalysis in real time is just around the corner - well almost (1994) (0)
- Metabolism and excretion of guanoxan in human. (1971) (0)
- Pharmacokinetic data on antidepressant agents (1992) (0)
- The Role of Gangliosides in the Repair of the Damaged Nervous System (1991) (0)
- Stentomania and suicide genes in coronary artery disease (1996) (0)
- H.M.S. Lochinvar, Port Edgar. (1976) (0)
- Cost of treating HIV disease and associated infections (1997) (0)
- R&D in epilepsy (1992) (0)
- Book reviews (1984) (0)
- Book reviews (1987) (0)
- A pharmaceutical Braveheart — battle lines are drawn (1996) (0)
- Chromatography of antibiotics by G. H. Wagman and M. J. Weinstein (1984) (0)
- Book reviews (1985) (0)
- State of play of research into dementias (1996) (0)
- Novel PDE IV inhibitors: exploring their potential in asthma (1995) (0)
- Immersion, followed by acute pulmonary oedema. (1959) (0)
- Pharmacokinetic data on anti-gout and related agents (1992) (0)
- Pharmacokinetic data on antifungal agents (1992) (0)
- Pharmacokinetic data on monoamine-oxidase inhibitors and appetite suppressants (1992) (0)
- Pharmacokinetic data on barbiturates and related agents (1992) (0)
- HIV protease inhibitors - will they fulfil their promise? (1995) (0)
- Do efflux pumps hold the key to better antifungal treatment? (1998) (0)
- Progress in the treatment of opportunistic infections (1992) (0)
- The continuing advance of the sartans (2000) (0)
- Pharmacokinetic data on sulphonamides and other antibacterials (1992) (0)
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