David James

Q: What Schools Are Affiliated With David James

David James is affiliated with the following schools: Washington University in St. Louis, University of Queensland, University of Sydney, University of New South Wales, University of Kent

David James 's AcademicInfluence.com Rankings

David James

Biology

#5071

World Rank

#7462

Historical Rank

Cell Biology

#220

World Rank

#228

Historical Rank

biology Degrees

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Biology

Why Is David James Influential?

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According to Wikipedia, David Ernest James is a cell biologist who discovered the glucose transporter GLUT4. He has also been responsible for the molecular dissection of the intracellular trafficking pathways that regulate GLUT4 translocation to the cell surface, the topological mapping of the insulin signal transduction pathway, the creation of a method for studying in vivo metabolism in small animals, and the use of this method to gain insights into whole-animal fuel metabolism and homeostasis.

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David James 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Regulated transport of the glucose transporter GLUT4 (2002) (1151)
Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States (2006) (974)
Molecular cloning and characterization of an insulin-regulatable glucose transporter (1989) (844)
Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat (1991) (825)
Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase (2006) (774)
Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein (1988) (619)
Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure, and obesity in rats. (1986) (522)
Insulin resistance is a cellular antioxidant defense mechanism (2009) (481)
Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I (2008) (472)
Dose-response curves for in vivo insulin sensitivity in individual tissues in rats. (1985) (414)
Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway. (2008) (409)
Characterization of the Role of the Rab GTPase-activating Protein AS160 in Insulin-regulated GLUT4 Trafficking* (2005) (407)
Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat. (1991) (402)
Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. (2002) (389)
Heterogeneity of insulin action in individual muscles in vivo: euglycemic clamp studies in rats. (1985) (359)
Protein Phosphorylation: A Major Switch Mechanism for Metabolic Regulation (2015) (353)
Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2 (2013) (341)
A Role for Protein Kinase Bβ/Akt2 in Insulin-Stimulated GLUT4 Translocation in Adipocytes (1999) (328)
Extracellular Vesicles Provide a Means for Tissue Crosstalk during Exercise. (2018) (323)
Moving GLUT4: The Biogenesis and Trafficking of GLUT4 Storage Vesicles (1997) (316)
Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest (2017) (303)
IRS1-independent defects define major nodes of insulin resistance. (2008) (286)
Translocation of the glucose transporter (GLUT4) to the cell surface in permeabilized 3T3-L1 adipocytes: effects of ATP insulin, and GTP gamma S and localization of GLUT4 to clathrin lattices (1992) (284)
Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates. (2015) (282)
Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events (2004) (251)
Characterization of Munc-18c and Syntaxin-4 in 3T3-L1 Adipocytes (1997) (237)
A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation. (2015) (235)
Identification of a novel glucose transporter-like protein-GLUT-12. (2002) (226)
GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in Syntaxins 6 and 16 but not TGN38: involvement of an acidic targeting motif. (2003) (224)
Differential sorting of two glucose transporters expressed in insulin-sensitive cells. (1991) (222)
Insulin Increases Cell Surface GLUT4 Levels by Dose Dependently Discharging GLUT4 into a Cell Surface Recycling Pathway (2004) (221)
Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. (2007) (220)
Flotillin-1/Reggie-2 Traffics to Surface Raft Domains via a Novel Golgi-independent Pathway (2002) (218)
The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin- sensitive cells (1996) (213)
A Role for 14-3-3 in Insulin-stimulated GLUT4 Translocation through Its Interaction with the RabGAP AS160* (2006) (211)
GLUT4 exocytosis (2011) (209)
The serine/threonine kinase ULK1 is a target of multiple phosphorylation events. (2011) (209)
Exercise training, glucose transporters, and glucose transport in rat skeletal muscles. (1992) (195)
Molecular Identification of Two Novel Munc-18 Isoforms Expressed in Non-neuronal Tissues (*) (1995) (181)
High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform (2018) (180)
Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes. (2008) (177)
In vivo insulin sensitivity in the rat determined by euglycemic clamp. (1983) (172)
Intracellular Localization of Phosphatidylinositide 3-kinase and Insulin Receptor Substrate-1 in Adipocytes: Potential Involvement of a Membrane Skeleton (1998) (169)
Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway. (2019) (165)
Pigment epithelium-derived factor contributes to insulin resistance in obesity. (2009) (163)
Thirty sweet years of GLUT4 (2019) (160)
Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation (2001) (159)
Immunocytochemical and biochemical studies of GLUT4 in rat skeletal muscle. (1992) (158)
Vesicle-associated Membrane Protein 2 Plays a Specific Role in the Insulin-dependent Trafficking of the Facilitative Glucose Transporter GLUT4 in 3T3-L1 Adipocytes* (1998) (158)
Illuminating the dark phosphoproteome (2019) (157)
Compartment ablation analysis of the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 adipocytes. (1996) (157)
Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins (2007) (153)
The Role of Ca2+ in Insulin-stimulated Glucose Transport in 3T3-L1 Cells* (2001) (152)
Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. (2010) (150)
Syntaxin 7 is localized to late endosome compartments, associates with Vamp 8, and Is required for late endosome-lysosome fusion. (2000) (149)
Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes. (1995) (147)
Mapping Insulin/GLUT4 Circuitry (2011) (146)
Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst. (1997) (143)
Effects of exercise training on in vivo insulin action in individual tissues of the rat. (1985) (142)
Cellular localization and characterization of Glut 3 glucose transporter isoform in human brain. (1992) (140)
Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework. (2016) (140)
The Role of Phosphoinositide 3-Kinase C2α in Insulin Signaling* (2007) (140)
In vivo glucose metabolism in individual tissues of the rat. Interaction between epinephrine and insulin. (1986) (137)
Regulator of Fatty Acid Metabolism, Acetyl Coenzyme A Carboxylase 1, Controls T Cell Immunity (2014) (134)
The t-SNARE Syntaxin 4 Is Regulated during Macrophage Activation to Function in Membrane Traffic and Cytokine Secretion (2003) (132)
Molecular Dissection of the Munc18c/Syntaxin4 Interaction: Implications for Regulation of Membrane Trafficking (2006) (132)
GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus. (2002) (129)
Control of Adipocyte Differentiation in Different Fat Depots; Implications for Pathophysiology or Therapy (2015) (129)
Signalling through the insulin receptor. (2000) (125)
Differential regulation of two distinct glucose transporter species expressed in 3T3-L1 adipocytes: effect of chronic insulin and tolbutamide treatment. (1989) (124)
Characterization of Insulin-Responsive GLUT4 Storage Vesicles Isolated from 3T3-L1 Adipocytes (2000) (124)
Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type (1991) (124)
Improved glucose homeostasis and enhanced insulin signalling in Grb14‐deficient mice (2004) (122)
Syndet, an Adipocyte Target SNARE Involved in the Insulin-induced Translocation of GLUT4 to the Cell Surface* (1998) (121)
CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes. (2008) (120)
GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration (1993) (119)
Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans (2016) (118)
In vivo insulin resistance in individual peripheral tissues of the high fat fed rat: assessment by euglycaemic clamp plus deoxyglucose administration (1986) (118)
c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action. (2004) (114)
Effect of denervation or unweighting on GLUT-4 protein in rat soleus muscle. (1991) (112)
Polarized distribution of glucose transporter isoforms in Caco-2 cells. (1992) (112)
GLUT4 – At the Cross Roads Between Membrane Trafficking and Signal Transduction (2001) (111)
The aetiology and molecular landscape of insulin resistance (2021) (110)
Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function (2017) (110)
Insulin resistance, diabetes, and the insulin-regulated trafficking of GLUT-4 (1994) (108)
Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression. (2007) (108)
Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane. (2005) (108)
The GLUT4 code. (2008) (107)
Tomosyn Interacts with the t-SNAREs Syntaxin4 and SNAP23 and Plays a Role in Insulin-stimulated GLUT4 Translocation* (2003) (107)
How cells absorb glucose. (1992) (106)
A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets (2016) (105)
Intrinsic Depot-Specific Differences in the Secretome of Adipose Tissue, Preadipocytes, and Adipose Tissue–Derived Microvascular Endothelial Cells (2010) (102)
Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport or glycogen synthase in 3T3-L1 adipocytes. (1993) (100)
The efficient intracellular sequestration of the insulin-regulatable glucose transporter (GLUT-4) is conferred by the NH2 terminus (1992) (100)
Phosphorylation of the glucose transporter in rat adipocytes. Identification of the intracellular domain at the carboxyl terminus as a target for phosphorylation in intact-cells and in vitro. (1990) (99)
Effects of insulin on intracellular GLUT4 vesicles in adipocytes: evidence for a secretory mode of regulation. (2000) (99)
Effect of exercise on insulin receptor binding and kinase activity in skeletal muscle. (1989) (98)
Effects of altered glucose homeostasis on glucose transporter expression in skeletal muscle of the rat. (1990) (93)
The glucose transporter GLUT4 and the aminopeptidase vp165 colocalise in tubulo-vesicular elements in adipocytes and cardiomyocytes. (1997) (91)
Multi-Omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency (2018) (91)
Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity (2014) (90)
Stimulation of glucose transport and glucose transporter phosphorylation by okadaic acid in rat adipocytes. (1990) (88)
Insulin recruits GLUT4 from specialized VAMP2-carrying vesicles as well as from the dynamic endosomal/trans-Golgi network in rat adipocytes. (2000) (87)
Variations in the requirement for v-SNAREs in GLUT4 trafficking in adipocytes (2009) (87)
The amino terminus of GLUT4 functions as an internalization motif but not an intracellular retention signal when substituted for the transferrin receptor cytoplasmic domain (1994) (87)
Release of Insulin Receptor Substrate Proteins from an Intracellular Complex Coincides with the Development of Insulin Resistance* (2000) (87)
Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylationa (2014) (86)
Thrombin Stimulates Glucose Transport in Human Platelets via the Translocation of the Glucose Transporter GLUT-3 from α-Granules to the Cell Surface (1997) (86)
Relationship between endosomes and lysosomes. (2001) (86)
Differential regulation of secretory compartments containing the insulin-responsive glucose transporter 4 in 3T3-L1 adipocytes. (1999) (86)
Syntaxin 7 Complexes with Mouse Vps10p Tail Interactor 1b, Syntaxin 6, Vesicle-associated Membrane Protein (VAMP)8, and VAMP7 in B16 Melanoma Cells* (2001) (85)
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation (2018) (85)
Selective Insulin Resistance in Adipocytes* (2015) (84)
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance (2018) (84)
Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects (2013) (83)
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection (2021) (83)
An integrative systems genetic analysis of mammalian lipid metabolism (2019) (81)
Glucose Transporter (GLUT-4) Is Targeted to Secretory Granules in Rat Atrial Cardiomyocytes (1997) (81)
Characterization of a Distinct Plasma Membrane Macrodomain in Differentiated Adipocytes* (2002) (81)
Identification of a distal GLUT4 trafficking event controlled by actin polymerization. (2009) (81)
Heterogeneity of insulin action in muscle: influence of blood flow. (1986) (79)
Insulin-stimulated translocation of the HepG2/erythrocyte-type glucose transporter expressed in 3T3-L1 adipocytes. (1989) (79)
Molecular regulation of GLUT-4 targeting in 3T3-L1 adipocytes (1995) (79)
A Novel Hook‐Related Protein Family and the Characterization of Hook‐Related Protein 1 (2005) (78)
The role of phosphoinositide 3-kinase C2alpha in insulin signaling. (2007) (78)
Insulin stimulation of GLUT-4 translocation: a model for regulated recycling. (1994) (78)
Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes* (2009) (77)
Intrinsic differences of insulin receptor kinase activity in red and white muscle. (1986) (77)
Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle. (2014) (77)
A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane. (1998) (76)
Jejunal/kidney glucose transporter isoform (Glut-5) is expressed in the human blood-brain barrier. (1993) (76)
Chronic exercise compensates for insulin resistance induced by a high-fat diet in rats. (1989) (76)
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins (2013) (75)
mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes. (2016) (75)
Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association. (2008) (74)
Insulin Stimulates the Entry of GLUT4 into the Endosomal Recycling Pathway by a Quantal Mechanism (2004) (74)
Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment (2008) (73)
Muscle glucose metabolism in exercising rats: comparison with insulin stimulation. (1985) (72)
Isoproterenol stimulates phosphorylation of the insulin-regulatable glucose transporter in rat adipocytes. (1989) (71)
Exercise-induced hepatic glucose output is precisely sensitive to the rate of systemic glucose supply. (1985) (71)
Hyperinsulinemia suppresses glucose utilization in specific brain regions: in vivo studies using the euglycemic clamp in the rat. (1985) (71)
Terminal Galactosylation and Sialylation Switching on Membrane Glycoproteins upon TNF-Alpha-Induced Insulin Resistance in Adipocytes* (2015) (70)
Muscle and adipose tissue insulin resistance: malady without mechanism? (2018) (70)
The cytosolic C-terminus of the glucose transporter GLUT4 contains an acidic cluster endosomal targeting motif distal to the dileucine signal. (2000) (69)
Amplification and Demultiplexing in Insulin-regulated Akt Protein Kinase Pathway in Adipocytes* (2011) (69)
A potent in vivo effect of ciglitazone on muscle insulin resistance induced by high fat feeding of rats. (1989) (66)
Effect of exercise training on whole-body insulin sensitivity and responsiveness. (1984) (65)
Subcutaneous fat transplantation alleviates diet-induced glucose intolerance and inflammation in mice (2014) (65)
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo (2014) (64)
Phosphorylation‐dependent binding of 14‐3‐3 terminates signalling by the Gab2 docking protein (2008) (64)
The Rab GTPase-Activating Protein TBC1D4/AS160 Contains an Atypical Phosphotyrosine-Binding Domain That Interacts with Plasma Membrane Phospholipids To Facilitate GLUT4 Trafficking in Adipocytes (2012) (64)
An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake (2015) (62)
The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle (2015) (60)
Activation of AMPK by Bitter Melon Triterpenoids Involves CaMKKβ (2013) (60)
Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival (2017) (59)
Nocodazole Inhibits Insulin-stimulated Glucose Transport in 3T3-L1 Adipocytes via a Microtubule-independent Mechanism* (2001) (58)
Effect of acute exercise and prolonged training on insulin response to intravenous glucose in vivo in rat. (1983) (58)
Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide (2012) (58)
High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice (2018) (57)
GLUT4 Overexpression or Deficiency in Adipocytes of Transgenic Mice Alters the Composition of GLUT4 Vesicles and the Subcellular Localization of GLUT4 and Insulin-responsive Aminopeptidase* (2004) (57)
Biogenesis of Insulin‐Responsive GLUT4 Vesicles is Independent of Brefeldin A‐Sensitive Trafficking (2000) (56)
Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation Motifs (2015) (56)
Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry (2015) (56)
Adipsin and the Glucose Transporter GLUT4 Traffic to the Cell Surface via Independent Pathways in Adipocytes (2000) (55)
Feedback inhibition of insulin gene expression by insulin. (1992) (55)
Snapin Interacts with the Exo70 Subunit of the Exocyst and Modulates GLUT4 Trafficking* (2008) (54)
Cluster Analysis of Insulin Action in Adipocytes Reveals a Key Role for Akt at the Plasma Membrane* (2009) (53)
Carcinogenic Chromium(VI) Compounds Formed by Intracellular Oxidation of Chromium(III) Dietary Supplements by Adipocytes. (2016) (53)
Differential targeting of facilitative glucose transporters in polarized epithelial cells. (1996) (53)
The cytosolic C-terminus of the glucose transporter GLUT4 contains an acidic cluster endosomal targeting motif distal to the dileucine signal (2000) (52)
Next-generation Akt inhibitors provide greater specificity: effects on glucose metabolism in adipocytes. (2011) (51)
GLUT4 phosphorylation and inhibition of glucose transport by dibutyryl cAMP. (1993) (51)
Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation. (2007) (51)
The RalA GTPase Is a Central Regulator of Insulin Exocytosis from Pancreatic Islet Beta Cells* (2008) (50)
The Geometric Framework for Nutrition as a tool in precision medicine (2017) (50)
Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes* (2015) (50)
Cellular and molecular biology of the Beta cell (1992) (49)
Time Dependence of Insulin Action in Muscle and Adipose Tissue in the Rat In Vivo: An Increasing Response in Adipose Tissue with Time (1985) (49)
Genetic Ablation of the c-Cbl Ubiquitin Ligase Domain Results in Increased Energy Expenditure and Improved Insulin Action (2006) (48)
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt (2019) (48)
No evidence for expression of the Insulin-regulatable glucose transporter in endothelial cells (1990) (48)
Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism. (2017) (47)
Developmental expression of insulin-regulatable glucose transporter GLUT-4. (1992) (47)
Casitas b-lineage lymphoma-deficient mice are protected against high-fat diet-induced obesity and insulin resistance. (2006) (46)
Proteomic Analysis of Human Plasma during Intermittent Fasting (2019) (46)
Glucose transport in L6 myoblasts overexpressing GLUT1 and GLUT4. (1993) (46)
Insulin-Regulated Trafficking of GLUT4 Requires Ubiquitination (2010) (45)
14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function (2016) (44)
The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport (2003) (44)
PP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells (2016) (44)
MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene (2015) (44)
Structural Basis for Phosphorylation and Lysine Acetylation Cross-talk in a Kinase Motif Associated with Myocardial Ischemia and Cardioprotection* (2014) (44)
Analysis of amino and carboxy terminal GLUT-4 targeting motifs in 3T3-L1 adipocytes using an endosomal ablation technique. (1999) (43)
Interaction of Insulin and Exercise on Glucose Transport in Muscle (1992) (43)
Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway* (2015) (42)
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry (2019) (42)
mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3 (2016) (42)
Global Phosphoproteomics Identifies a Major Role for AKT and 14-3-3 in Regulating EDC3* (2010) (41)
Targeting of mammalian glucose transporters. (1993) (41)
Insulin and Oleate Promote Translocation of Inosine‐5′ Monophosphate Dehydrogenase to Lipid Bodies (2004) (40)
Insulin-regulated sorting of glucose transporters in 3T3-L1 adipocytes. (1992) (40)
TBC1D13 is a RAB35 Specific GAP that Plays an Important Role in GLUT4 Trafficking in Adipocytes (2012) (40)
Purification of insulin-dependent exocytic vesicles containing the glucose transporter. (1987) (40)
Exercise-induced molecular mechanisms promoting glycogen supercompensation in human skeletal muscle (2018) (39)
Acute bidirectional manipulation of muscle glucose uptake by in vivo electrotransfer of constructs targeting glucose transporter genes. (2005) (39)
Multiplexed Temporal Quantification of the Exercise-regulated Plasma Peptidome* (2017) (38)
MASTL overexpression promotes chromosome instability and metastasis in breast cancer (2018) (38)
Protein Kinase C Epsilon Deletion in Adipose Tissue, but Not in Liver, Improves Glucose Tolerance. (2019) (37)
Positive-unlabeled ensemble learning for kinase substrate prediction from dynamic phosphoproteomics data (2015) (34)
Novel isoform of syntaxin 1 is expressed in mammalian cells. (1997) (34)
Quantitative proteomic analysis of the adipocyte plasma membrane. (2011) (34)
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy (2020) (33)
Metabolomic analysis of insulin resistance across different mouse strains and diets (2017) (32)
GLUT4 facilitates insulin stimulation and cAMP-mediated inhibition of glucose transport. (1992) (30)
Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass. (2016) (30)
DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake (2014) (30)
Mammalian target of rapamycin complex 2 regulates muscle glucose uptake during exercise in mice (2017) (30)
Novel Systems for Dynamically Assessing Insulin Action in Live Cells Reveals Heterogeneity in the Insulin Response (2013) (29)
MUNC-ing around with insulin action. (2005) (29)
Carboxy terminus of glucose transporter 3 contains an apical membrane targeting domain. (2004) (29)
Characterization of the intracellular GLUT-4 compartment. (1995) (29)
Akt inhibitors reduce glucose uptake independently of their effects on Akt. (2010) (28)
Development of a human skeletal micro muscle platform with pacing capabilities. (2019) (28)
Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction (2014) (28)
The Role of Ca 2 1 in Insulin-stimulated Glucose Transport in 3 T 3L 1 Cells * (2001) (27)
Increased expression of the SNARE accessory protein Munc18c in lipid-mediated insulin resistance Published, JLR Papers in Press, April 16, 2003. DOI 10.1194/jlr.M300003-JLR200 (2003) (27)
Regulation of the Endosomal SNARE Protein Syntaxin 7 by Colony-Stimulating Factor 1 in Macrophages (2008) (27)
A gene expression signature for insulin resistance. (2011) (27)
Recombinant Sindbis virus as an expression system for cell biology. (1994) (26)
Botulinum E toxin light chain does not cleave SNAP-23 and only partially impairs insulin stimulation of GLUT4 translocation in 3T3-L1 cells. (1997) (25)
Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass (2018) (25)
Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway (2014) (25)
Lactate production is a prioritized feature of adipocyte metabolism (2019) (25)
Tankyrase modulates insulin sensitivity in skeletal muscle cells by regulating the stability of GLUT4 vesicle proteins (2018) (25)
Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes (2019) (25)
Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models (2019) (24)
Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training (2018) (24)
PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications (2015) (23)
KinasePA: Phosphoproteomics data annotation using hypothesis driven kinase perturbation analysis (2016) (22)
Insulin signaling requires glucose to promote lipid anabolism in adipocytes (2020) (22)
PhosR enables processing and functional analysis of phosphoproteomic data (2020) (22)
The Effect of Hyperinsulinemia on Glucose Homeostasis During Moderate Exercise in Man (1982) (22)
Small-protein Enrichment Assay Enables the Rapid, Unbiased Analysis of Over 100 Low Abundance Factors from Human Plasma* (2019) (22)
Mutational analysis of the carboxy-terminal phosphorylation site of GLUT-4 in 3T3-L1 adipocytes. (1998) (22)
Growth Factor-Dependent and -Independent Activation of mTORC2 (2019) (21)
The Role of the Niemann-Pick Disease, Type C1 Protein in Adipocyte Insulin Action (2014) (21)
The effect of exercise training on glycogen, glycogen synthase and phosphorylase in muscle and liver (2004) (21)
Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake. (2018) (21)
Fractionation of endocytic vesicles and glucose-transporter-containing vesicles in rat adipocytes. (1988) (21)
SnapShot: Insulin/IGF1 Signaling (2015) (21)
The Role of Ca in Insulin-stimulated Glucose Transport in 3T3-L1 Cells* (2001) (20)
Mini-Review on the Cellular Mechanisms of Disease (1994) (19)
Dissecting the Mechanism of Insulin Resistance Using a Novel Heterodimerization Strategy to Activate Akt* (2009) (19)
Proteomics analysis of adipose depots after intermittent fasting reveals visceral fat preservation mechanisms. (2021) (19)
Targeting of the insulin-regulatable glucose transporter (GLUT-4). (1994) (18)
mTORC2 regulates muscle glucose uptake during exercise in mice (2017) (18)
Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase* (2012) (18)
The Weak Complex between RhoGAP Protein ARHGAP22 and Signal Regulatory Protein 14-3-3 Has 1∶2 Stoichiometry and a Single Peptide Binding Mode (2012) (18)
ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation (2019) (18)
A generalised enzyme kinetic model for predicting the behaviour of complex biochemical systems (2015) (17)
Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin (2020) (17)
In vivo dose response curves of insulin action in heart: anomalous effects at high insulin doses. (1985) (16)
Perspectives in Diabetes Moving GLUT 4 The Biogenesis and Trafficking of GLUT 4 Storage Vesicles (2010) (16)
Kinetic Trans-omic Analysis Reveals Key Regulatory Mechanisms for Insulin-Regulated Glucose Metabolism in Adipocytes (2020) (16)
Nutritional reprogramming of mouse liver proteome is dampened by metformin, resveratrol, and rapamycin. (2021) (16)
PGC1α Controls Sucrose Taste Sensitization in Drosophila. (2020) (16)
ORTI: An Open-Access Repository of Transcriptional Interactions for Interrogating Mammalian Gene Expression Data (2016) (16)
Identification of RhoGAP22 as an Akt-Dependent Regulator of Cell Motility in Response to Insulin (2011) (15)
RagC phosphorylation autoregulates mTOR complex 1 (2018) (15)
An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction (2017) (15)
Insulin‐regulatable phosphoproteins in 3T3‐L1 adipocytes form detergent‐insoluble complexes not associated with caveolin (1997) (15)
Hyperactivation of the Insulin Signaling Pathway Improves Intracellular Proteostasis by Coordinately Up-regulating the Proteostatic Machinery in Adipocytes* (2016) (15)
Muscling in on GLUT4 kinetics (2010) (15)
The RabGAP TBC 1 D 1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle (2015) (15)
Personalized phosphoproteomics identifies functional signaling (2021) (15)
GLUT4 trafficking in insulin-sensitive cells. A morphological review. (1999) (15)
High-throughput analysis of the dynamics of recycling cell surface proteins. (2008) (15)
Insulin precipitation in artificial infusion devices (1981) (14)
The amino acid transporter, SLC1A3, is plasma membrane‐localised in adipocytes and its activity is insensitive to insulin (2017) (14)
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells (2021) (14)
Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance (2021) (14)
Membrane boundary extraction using circular multiple paths (2009) (14)
Erratum: c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action (Journal of Clinical Investigation (2004) 114 (1326-1333) (doi:10.1172/JCI200421480)) (2005) (13)
Phosphoproteomics of Acute Cell Stressors Targeting Exercise Signaling Networks Reveal Drug Interactions Regulating Protein Secretion. (2019) (13)
The subcellular fractionation properties and function of insulin receptor substrate-1 (IRS-1) are independent of cytoskeletal integrity. (2006) (13)
Automatic identification of fusion events in TIRF microscopy image sequences (2009) (13)
Quantification of exercise‐regulated ubiquitin signaling in human skeletal muscle identifies protein modification cross talk via NEDDylation (2020) (13)
Signaling Heterogeneity is Defined by Pathway Architecture and Intercellular Variability in Protein Expression (2021) (12)
Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies (2016) (12)
ISL1 Regulates Peroxisome Proliferator-Activated Receptor γ Activation and Early Adipogenesis via Bone Morphogenetic Protein 4-Dependent and -Independent Mechanisms (2014) (12)
RalA GTPase Tethers Insulin Granules to L‐ and R‐Type Calcium Channels Through Binding α2δ‐1 Subunit (2013) (12)
Defining the protein and lipid constituents of tubular recycling endosomes (2020) (12)
Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4. (2003) (12)
Lactate production is a prioritized feature of adipocyte metabolism. (2020) (10)
Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis (2021) (10)
Snareing GLUT4 at the plasma membrane in muscle and fat. (1998) (10)
Systems-level analysis of insulin action in mouse strains provides insight into tissue- and pathway-specific interactions that drive insulin resistance (2022) (10)
Rate-oriented trans-omics: integration of multiple omic data on the basis of reaction kinetics (2019) (10)
The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes (2018) (10)
GLUT4 trafficking in a test tube. (2005) (10)
Insulin action under arrestin. (2009) (10)
GLUT4 trafficking in insulin-sensitive cells (1999) (10)
Distinct localization of renin and GLUT-4 in juxtaglomerular cells of mouse kidney. (1998) (9)
Dataset from the global phosphoproteomic mapping of early mitotic exit in human cells (2015) (9)
Bicarbonate alters cellular responses in respiration assays. (2017) (9)
Cross-species gene expression analysis identifies a novel set of genes implicated in human insulin sensitivity (2015) (9)
The role of mitochondrial reactive oxygen species in insulin resistance. (2021) (9)
Endosomal sorting of GLUT4 and Gap1 is conserved between yeast and insulin-sensitive cells (2013) (9)
Simple, robust strategies for generating DNA-directed RNA interference constructs. (2005) (9)
Phenotypic Discrepancies in Acetyl-CoA Carboxylase 2-deficient Mice (2012) (9)
Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1 (2020) (9)
Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses (2015) (9)
A modified gas-trapping method for high-throughput metabolic experiments in Drosophila melanogaster. (2019) (8)
Minimal impact of age and housing temperature on the metabolic phenotype of Acc2-/- mice. (2016) (8)
Towards fully automated identification of vesicle-membrane fusion events in TIRF microscopy (2009) (8)
The insulin-regulatable glucose transporter GLUT-4 (1995) (7)
A hierarchical approach to removal of unwanted variation for large-scale metabolomics data (2020) (7)
Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet (2021) (7)
CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion (2020) (7)
Re-fraction: a machine learning approach for deterministic identification of protein homologues and splice variants in large-scale MS-based proteomics. (2012) (7)
Mitochondrial oxidants, but not respiration, are sensitive to glucose in adipocytes (2019) (7)
Molecular Regulation of GLUT4 Targeting in 3 T 3L 1 Adipocytes (2002) (7)
Highlights from the 11th ISCB Student Council Symposium 2015 (2016) (7)
Insulin Tolerance Test under Anaesthesia to Measure Tissue-specific Insulin-stimulated Glucose Disposal. (2019) (7)
Glucose Transport: Methods for Interrogating GLUT4 Trafficking in Adipocytes. (2018) (7)
Dissecting the biology of mTORC1 beyond rapamycin (2021) (6)
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry (2020) (6)
Mitochondrial oxidants, but not respiration, are sensitive to glucose in adipocytes. (2020) (6)
Plasma bile acids more closely align with insulin resistance, visceral and hepatic adiposity than total adiposity. (2020) (6)
A gas trapping method for high-throughput metabolic experiments. (2018) (6)
Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling (2019) (5)
Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate (2022) (5)
Crystallization and preliminary X-ray diffraction of the Munc18c-syntaxin4 (1-29) complex. (2007) (5)
Membrane Topology of Trafficking Regulator of GLUT4 1 (TRARG1). (2018) (5)
Towards fully automated Identification of Vesicle‐Membrane Fusion Events in TIRF Microscopy (2007) (5)
Distinct localization of renin and GLUT-4 in juxtaglomerular cells of mouse kidney. (1998) (5)
Dynamic 13C Flux Analysis Captures the Reorganization of Adipocyte Glucose Metabolism in Response to Insulin (2020) (5)
Structural insights into Ras regulation by SIN1 (2022) (4)
Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q (2021) (4)
Glut4 Is Targeted to Secretory Granules in Rat Atrial Cardiomyocytes (1997) (4)
Small-protein Enrichment Assay Enables the Rapid, Unbiased Analysis of Over 100 Low Abundance Factors from Human Plasma. (2019) (4)
Rapid pulsatile corticosterone secretion in the rat is not confirmed (1981) (4)
Crystallization and preliminary X-ray diffraction of the Munc18c–syntaxin41–29 complex (2007) (4)
Bromodomain and Extraterminal Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection (Pre-Clinical) (2020) (3)
Acetyl-CoA carboxylase-1 is a critical regulator of beta cell size and proliferation (2013) (3)
Unravelling signal coordination from large scale phosphorylation kinetic data (2016) (3)
The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport (2003) (3)
Discovery of drugs to treat cytokine storm-induced cardiac dysfunction using human cardiac organoids (2020) (3)
An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake (2016) (2)
Defining the Nutritional an d Metabolic Context of FGF 21 Using the Geometric Framework Graphical (2016) (2)
Characterisation of proteins associated with the GLUT4 intracellular compartment. (1997) (2)
Genome-wide analysis in Drosophila reveals diet-by-gene interactions and uncovers diet-responsive genes (2019) (2)
Cell Metabolism Resource Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC 2 (2014) (2)
VIA A TGN SUBDOMAIN ENRICHED IN SYNTAXINS 6 AND 16 BUT NOT TGN 38 : INVOLVEMENT OF AN ACIDIC TARGETING MOTIF (2002) (2)
Systemic vascular endothelial growth factor-A (VEGF-A) neutralization ameliorates diet induced metabolic dysfunction (2014) (2)
The impact of weight cycling on health outcomes in animal models: A systematic review and meta‐analysis (2022) (2)
Trafficking of the glucose transporter GLUT4 via the TGN: involvement of an acidic motif and Syntaxins 6 and 16 (2002) (1)
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance (2022) (1)
The Efficient IntraceUular Sequestration of the Insulin-regulatable Glucose Transporter (GLUT-4) Is Conferred by the NH2 Terlmnus (2002) (1)
PFKFB3 and insulin signalling (2015) (1)
hRUV: Hierarchical approach to removal of unwanted variation for large- 1 scale metabolomics data 2 (2021) (1)
PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modifications (2015) (1)
GLUT4 TRAFFIC REPORT: MOLECULAR MECHANISMS OF INSULIN-STIMULATED GLUT4 TRAFFICKING IN ADIPOCYTES (2002) (1)
Decision letter: A highly responsive pyruvate sensor reveals pathway-regulatory role of the mitochondrial pyruvate carrier MPC (2020) (1)
Universitet mTORC 2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3 (2016) (1)
A Positive Feedback Loop between Akt andmTORC 2 via SIN 1 Phosphorylation Graphical (1)
Identifying a GSK3-TRARG1 signaling axis reveals BCL9L as a novel regulator of GLUT4 trafficking (2020) (1)
Overexpression of Glut4 in adipocytes of transgenic mice saturates sorting. (1996) (1)
Automating the quantification of membrane proteins under confocal microscopy (2012) (1)
Regulated versus Constitutive Secretion – A Major Form of Intercellular Communication (2016) (1)
Glut-4 and Vamp-2 Are Segregated From Early Endosomes in Insulin-Sensitive But Not in Non-Insulin Sensitive Cells (1995) (1)
Membrane Boundary Extraction Using a Circular Shortest Path Technique (2007) (1)
New Cucurbitane triterpenoids from bitter melon with potent antidiabetic properties associated with activation of AMPK (2008) (1)
Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection. (2014) (1)
KINETIC EVIDENCE FOR UNIQUE REGULATION OF GLUT4 TRAFFICKING BY INSULIN AND AMPK ACTIVATORS IN L6 MYOTUBES (2009) (1)
Genetic Architecture of Heart Mitochondrial Proteome influencing Cardiac Hypertrophy (2021) (1)
Secreted adipocyte fatty acid binding protein (FABP4) forms the molecular basis of the adipo-insular axis (2010) (0)
Heterogeneity of in vivo insulin sensitivity among individual tissues studies using the euglycemic clamp in the rat (1984) (0)
The SM Protein Vps45p Acts as a t-SNARE Chaperone and Positively Regulates SNARE Complex Formation (2001) (0)
Triterpenoids extracted from bitter melon activate AMPK via a mechanism involving the upstream AMPK kinase CaMKKa/b (2011) (0)
Heme oxygenase-1 regulates mitochondrial coenzyme Q and reactive oxygen species formation - possible implications for the metabolic reprogramming in response to hypoxia (2012) (0)
Circulating bile acids are associated with insulin resistance and visceral and liver fat in human subjects (2019) (0)
Systems biology – The next frontier in metabolic research (2014) (0)
Proteomic Analysis of Mammalian Cells in Culture (2000) (0)
Table S1. Inhibitor Screen Insulin-Regulated Phosphorylation Sites, Related to Figure 1 (2013) (0)
Correction: The role of the Niemann-Pick disease, type C1 protein in adipocyte insulin action (2014) (0)
Localisation of BP165 and GLUT4 insulin-regulatable tissues. (1996) (0)
232 RELATIONSHIP BETWEEN TOTAL GLUCOSE TRANSPORTER PROTEIN CONTENT AND MAXIMALLY-STIMULATABLE GLUCOSE TRANSPORT IN RAT SKELETAL MUSCLES (1990) (0)
Adipocytes Membrane Macrodomain in Differentiated Characterization of a Distinct Plasma FUNCTION AND BIOGENESIS: MEMBRANE TRANSPORT STRUCTURE (2014) (0)
Obese, yet insulin sensitive humans (2011) (0)
Mapping the insulin signalling network (2013) (0)
S24-1 - Molecular mapping of insulin action and insulin resistance (2016) (0)
A novel actin filament class that regulates glucose uptake and GLUT4 trafficking (2011) (0)
Table S3. Class I Phosphorylation Sites, Related to Figure 1 (2013) (0)
MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene (2015) (0)
Table S2. All Identified Phosphorylation Sites, Related to Figure 1 (2013) (0)
Corrigendum to: An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake [Traic, (2015), 16, 7, 691-711] (2016) (0)
The intracellular locality of insulin receptor substrate 1 (IRS-1): Putting PI 3-kinase in its place (1998) (0)
Minireview: The GLUT4 Code (2008) (0)
Colocalization of the Atrial-Natriuretic-Factor and a Glucose-Transporter in Rat Cardiomyocytes (1995) (0)
Identifying the enemy in the battle against diabetes and obesity (2011) (0)
Structural insights into the SM protein–syntaxin interactions (2008) (0)
Identification of a novel player in insulin‐mediated lipolysis inhibition (2020) (0)
Decision letter: TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states (2020) (0)
Invited talk: Mapping complex molecular networks underlying exercise using global phosphoproteomics (2019) (0)
Use of a GLUT4 translocation assay strategy to identify new insulin sensitisers with efficacy in vitro and in vivo (2008) (0)
sugar/polyol transport facilitators Nomenclature of the GLUT/SLC2A family of (2011) (0)
Correction: Unraveling Kinase Activation Dynamics Using Kinase-Substrate Relationships from Temporal Large-Scale Phosphoproteomics Studies (2017) (0)
Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection (2020) (0)
Acetyl-CoA carboxylase 1 is a critical regulator of beta cell mass (2013) (0)
Supplementary Figures and Methods (2013) (0)
Author response: Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis (2021) (0)
Mike Mueckler (1953-2021) - the father of the mammalian SLC2 glucose transporter family. (2021) (0)
Investigation into the association of IRS-1 with the cytoskeleton (2001) (0)
Vascular cells improve functionality of human cardiac organoids. (2023) (0)
A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology (2022) (0)
Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function (2022) (0)
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells (2021) (0)
The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes (2018) (0)
Proceedings of the 2nd Annual National Viticulture Research Conference (2017) (0)
Crystal structure of the Munc18c/Syntaxin4 N-peptide complex (2007) (0)
202-LB: Insulin Regulation of Lipolysis in Adipocytes (2022) (0)
Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training (2018) (0)
Bacterial Proteome Analysis During Transition from Exponential to Stationary Phase (2000) (0)
SILAC kinase screen identifies potential MASTL substrates (2022) (0)
Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance (2023) (0)
Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle (2023) (0)
SILAC kinase screen identifies potential MASTL substrates (2022) (0)
Deep Proteome Profiling of White Adipose Tissue Reveals Marked Conservation and Distinct Features Between Different Anatomical Depots (2022) (0)
Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2. (2023) (0)
High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform (2018) (0)
Core functional nodes and sex-specific pathways in human ischaemic and dilated cardiomyopathy (2020) (0)
Genome wide analysis in Drosophila reveals diet by gene interactions and uncovers diet- 1 responsive genes 2 (2021) (0)
Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice. (2012) (0)
COMMENTARY Targeting of mammalian glucose transporters (1993) (0)
An integrative systems genetic analysis of mammalian lipid metabolism (2019) (0)
Microtubule integrity is not required for insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes (2001) (0)
Macrophage infiltration and cytokine release in adipose tissue: angiogenesis or inflammation? (2010) (0)
PSMD9 identified as a novel regulator of hepatic acylglycerol metabolism using an integrated systems-biology approach (2019) (0)
C-CBL Is a Critical Negative Regulator of Megakaryopoesis (2014) (0)
Erratum (1993) (0)
OP77 THE RABGAP TBC1D1 PLAYS A CENTRAL ROLE IN EXERCISE REGULATED GLUCOSE METABOLISM IN SKELETAL MUSCLE (2014) (0)
Insulin and PDGF stimulate PI 3-kinase at distinct intracellular sites: Implications for biological specificity (1996) (0)
GLUT4 trafficking and early endosomes in 3T3-L1 adipocytes (1997) (0)
The emergence of an insulin-responsive glucose transport system during adipocyte differentiation correlates with the segregation of GLUT4 from recycling endosomes (2001) (0)
Highlights from the eleventh ISCB Student Council Symposium 2015-DTU Orbit (03/12/2018) (2017) (0)
Metabolic flux analysis in insulin-stimulated adipocytes form temporal patterns of intracellular metabolome data (2016) (0)
A co-receptor that represses beta-cell insulin action (2021) (0)
Big data from bench to bedside to population in diabetes care (2016) (0)
Mutational analysis of the carboxy-terminal phosphorylation site of GLUT-4 in 3T3-L1 adipocytes. (1998) (0)
SnapShot: Insulin/IGF1 Signaling (2015) (0)
Resource Extracellular Vesicles Pro vide a Means for Tissue Crosstalk during Exercise Graphical (2019) (0)
Characterization of the Munc18-Syntaxin protein interaction (2008) (0)
Genome-wide analysis of diet and gene interactions in Drosophila uncovers the glucose transporter, CG4607, as a diet-responsive gene (2019) (0)
Corrigendum to ‘ABHD15 regulates adipose tissue lipolysis and hepatic lipid accumulation’ [Molecular Metabolism 25 (2019) p.83–94] (2021) (0)
Insulin-sensitive overweight/obese individuals remain as insulin sensitive and normotensive as lean subjects over 6 years (2019) (0)
PNAS Plus Significance Statements (2013) (0)
Genetic architecture of a healthy diet in Drosophila (2019) (0)
Glucose Transport in 3T3-L1 Cells in Insulin-stimulated 2+ The Role of Ca (2014) (0)

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