David Michael Kranz

David Michael Kranz's AcademicInfluence.com Rankings

David Michael Kranz

Biology

#11920

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#15354

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Immunology

#784

World Rank

#807

Historical Rank

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Biology

David Michael Kranz's Degrees

Bachelors Biology Stanford University

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David Michael Kranz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells (2011) (878)
Positive and negative selection of an antigen receptor on T cells in transgenic mice (1988) (798)
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences (1984) (625)
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes (1984) (515)
Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma. (2016) (412)
Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2 (2020) (394)
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation. (2003) (377)
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells (2007) (374)
Structure, organization, and somatic rearrangement of T cell gamma genes (1985) (355)
T‐cell receptor binding affinities and kinetics: impact on T‐cell activity and specificity (2009) (336)
THE MIT ALEWIFE MACHINE: A LARGE-SCALE DISTRIBUTED-MEMORY MULTIPROCESSOR (1991) (330)
In vitro evolution of a T cell receptor with high affinity for peptide/MHC. (2000) (303)
Faculty Opinions recommendation of Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. (2010) (285)
How a Single T Cell Receptor Recognizes Both Self and Foreign MHC (2007) (265)
T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. (2011) (239)
TCRs with high affinity for foreign pMHC show self-reactivity (2003) (232)
Directed evolution of a stable scaffold for T-cell receptor engineering (2000) (231)
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency. (1999) (219)
Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. (1984) (183)
Alanine Scanning Mutagenesis of an αβ T Cell Receptor: Mapping the Energy of Antigen Recognition (1998) (176)
Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen Receptors. (2016) (170)
Selection of functional T cell receptor mutants from a yeast surface-display library. (1999) (170)
Limited diversity of the rearranged T-cell γ gene (1985) (169)
Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. (1984) (161)
Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2Kb (2003) (141)
Isolation of anti-T cell receptor scFv mutants by yeast surface display. (1997) (136)
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. (1986) (133)
Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. (2013) (133)
Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity. (1996) (118)
Faculty Opinions recommendation of A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy. (2011) (115)
Cd8− T Cell Transfectants That Express a High Affinity T Cell Receptor Exhibit Enhanced Peptide-Dependent Activation (2001) (109)
Efficient tumor cell lysis mediated by a bispecific single chain antibody expressed in Escherichia coli. (1994) (106)
Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function. (2005) (102)
Mechanisms of ligand binding by monoclonal anti-fluorescyl antibodies. (1982) (101)
High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3. (2005) (98)
Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains (2018) (98)
Conjugates of folate and anti-T-cell-receptor antibodies specifically target folate-receptor-positive tumor cells for lysis. (1995) (97)
Chromosomal locations of the murine T-cell receptor alpha-chain gene and the T-cell gamma gene. (1985) (91)
Partial elucidation of an anti-hapten repertoire in BALB/c mice: comparative characterization of several monoclonal anti-fluorescyl antibodies. (1981) (87)
A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs) (2012) (86)
Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists (2007) (82)
Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies (2013) (82)
The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness1 (2009) (81)
Heteroantibody duplexes target cells for lysis by cytotoxic T lymphocytes. (1985) (81)
Role of the T Cell Receptor α Chain in Stabilizing TCR-Superantigen-MHC Class II Complexes (1999) (80)
High affinity T cell receptors from yeast display libraries block T cell activation by superantigens. (2001) (80)
TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity. (2015) (79)
Blockade of T Cell Activation Using a Surface-Linked Single-Chain Antibody to CTLA-4 (CD152)1 (2000) (79)
Thermodynamic properties of ligand binding by monoclonal anti-fluorescyl antibodies. (1986) (74)
Staphylococcal superantigens cause lethal pulmonary disease in rabbits. (2010) (73)
Equilibrium between host and cancer caused by effector T cells killing tumor stroma. (2008) (72)
Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition. (1998) (71)
Engineering higher affinity T cell receptors using a T cell display system. (2008) (69)
Characterization of a single-chain T-cell receptor expressed in Escherichia coli. (1992) (68)
Antigen recognition and allogeneic tumor rejection in CD8+ TCR transgenic/RAG(-/-) mice. (1997) (68)
Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters (2012) (65)
Estrogen induction of the granzyme B inhibitor, proteinase inhibitor 9, protects cells against apoptosis mediated by cytotoxic T lymphocytes and natural killer cells. (2006) (65)
Structural interplay between germline and adaptive recognition determines TCR-peptide-MHC cross-reactivity (2015) (63)
Resistance of cytotoxic T lymphocytes to the lytic effects of their toxic granules (1987) (63)
Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection. (2013) (63)
Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor. (2001) (61)
Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes. (1987) (61)
Display, engineering, and applications of antigen-specific T cell receptors. (2007) (60)
Structural basis of T‐cell specificity and activation by the bacterial superantigen TSST‐1 (2007) (60)
Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments. (2009) (59)
Role of 2c T Cell Receptor Residues in the Binding of Self–And Allo–Major Histocompatibility Complexes (2000) (59)
Characterization of T cell receptors engineered for high affinity against toxic shock syndrome toxin-1. (2005) (58)
Long-range cooperative binding effects in a T cell receptor variable domain. (2006) (58)
Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation1 (2008) (57)
A functional γ gene formed from known γ-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes (1986) (57)
Expression of the T-cell-specific γ gene is unnecessary in T cells recognizing class II MHC determinants (1985) (56)
TCR Scanning of Peptide/MHC through Complementary Matching of Receptor and Ligand Molecular Flexibility (2014) (55)
The Study of High-Affinity TCRs Reveals Duality in T Cell Recognition of Antigen: Specificity and Degeneracy1 (2006) (54)
Disulfide Bond Engineering to Trap Peptides in the MHC Class I Binding Groove1 (2007) (53)
Single-chain Fv/folate conjugates mediate efficient lysis of folate-receptor-positive tumor cells. (1997) (52)
Engineering and Characterization of a Stabilized α1/α2 Module of the Class I Major Histocompatibility Complex Product Ld* (2006) (51)
Nonrandom use of J alpha gene segments. Influence of V alpha and J alpha gene location. (1991) (51)
Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains (2011) (51)
Directed evolution of a single-chain class II MHC product by yeast display. (2003) (50)
Engineering the binding properties of the T cell receptor:peptide:MHC ternary complex that governs T cell activity. (2009) (47)
Solution mapping of T cell receptor docking footprints on peptide-MHC (2007) (47)
A model T-cell receptor system for studying memory T-cell development. (2003) (46)
Dissecting Cooperative and Additive Binding Energetics in the Affinity Maturation Pathway of a Protein-Protein Interface* (2003) (45)
T cell receptors: affinities, cross-reactivities, and a conformer model. (2004) (45)
Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity. (2012) (43)
Development of a novel strategy for engineering high-affinity proteins by yeast display. (2006) (43)
Binding energetics of T-cell receptors: correlation with immunological consequences. (1999) (43)
Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC (2007) (43)
Myxoma Virus Expressing a Fusion Protein of Interleukin-15 (IL15) and IL15 Receptor Alpha Has Enhanced Antitumor Activity (2014) (43)
IL-12 Treatment of Endogenously Arising Murine Brain Tumors1 (2000) (42)
Restricted reassociation of heavy and light chains from hapten-specific monoclonal antibodies. (1981) (42)
Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. (2005) (40)
Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex* (2016) (40)
A residue in the center of peptide QL9 affects binding to both Ld and the T cell receptor. (1996) (39)
Faculty Opinions recommendation of Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity. (2008) (38)
Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors. (2011) (38)
Effects of Complementarity Determining Region Mutations on the Affinity of an α/β T Cell Receptor: Measuring the Energy Associated with CD4/CD8 Repertoire Skewing (1999) (37)
Folate receptors as potential therapeutic targets in choroid plexus tumors of SV40 transgenic mice (1997) (37)
Expression profiling using a hexamer-based universal microarray (2004) (37)
Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes. (1999) (37)
A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control (2014) (36)
Glycosylation of the T-cell antigen-specific receptor and its potential role in lectin-mediated cytotoxicity. (1986) (35)
Folate-mediated targeting of T cells to tumors. (2004) (35)
The MIT Alewife Machine (1999) (35)
Binding properties and solubility of single-chain T cell receptors expressed in E. coli. (1996) (33)
Different thermodynamic binding mechanisms and peptide fine specificities associated with a panel of structurally similar high-affinity T cell receptors. (2008) (33)
Binding affinity and inhibitory properties of a single-chain anti-T cell receptor antibody. (1993) (32)
Treatment of an Aggressive Orthotopic Murine Glioblastoma Model with Combination Checkpoint Blockade and a Multivalent Neoantigen Vaccine. (2020) (32)
Interaction of Streptavidin-Based Peptide–MHC Oligomers (Tetramers) with Cell-Surface TCRs (2011) (31)
T-cell receptor delta-chain diversity in peripheral lymphocytes. (1989) (31)
Development and applications of surface-linked single chain antibodies against T-cell antigens. (2001) (30)
Generation of TCRs of higher affinity by antigen-driven differentiation of progenitor T cells in vitro (2017) (29)
Different Strategies Adopted by Kb and Ld to Generate T Cell Specificity Directed against Their Respective Bound Peptides* (2009) (28)
A yeast display system for engineering functional peptide-MHC complexes. (2003) (28)
Restoring immune tolerance in neuromyelitis optica (2016) (27)
Biosensor detection systems: engineering stable, high-affinity bioreceptors by yeast surface display. (2009) (26)
Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld. (2006) (26)
Specificity and binding properties of a single-chain T cell receptor. (1996) (26)
Changing the peptide specificity of a human T cell receptor by directed evolution (2014) (26)
Engineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of disease. (2013) (26)
MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR (2013) (25)
Costimulatory strength influences the differential effects of transforming growth factor beta1 for the generation of CD8+ regulatory T cells. (2008) (24)
Neuronal localization of indoleamine 2,3-dioxygenase in mice (2005) (23)
Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity. (2009) (23)
High-Throughput Stability Screening of Neoantigen/HLA Complexes Improves Immunogenicity Predictions (2018) (23)
Design of T cell receptor libraries with diverse binding properties to examine adoptive T cell responses (2012) (23)
A yeast surface display system for the discovery of ligands that trigger cell activation. (1998) (23)
Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides (2020) (22)
Modified hybridoma methodology: antigen-directed chemically mediated cell fusion. (1980) (22)
Targeting T cells against brain tumors with a bispecific ligand‐antibody conjugate (1998) (22)
Subtle changes at the variable domain interface of the T-cell receptor can strongly increase affinity (2017) (21)
Neutralization of multiple staphylococcal superantigens by a single-chain protein consisting of affinity-matured, variable domain repeats. (2008) (21)
Selection of variable-joining region combinations in the alpha chain of the T cell receptor. (1988) (21)
T cell receptor engineering. (2012) (21)
Assessing energetic contributions to binding from a disordered region in a protein-protein interaction . (2010) (21)
Restoring immune tolerance in neuromyelitis optica (2016) (21)
Generation of cytotoxic T-lymphocytes to a self-peptide/class I complex: a model for peptide-mediated tumor rejection. (1994) (20)
Mapping the Energy of Superantigen Staphylococcus Enterotoxin C3 Recognition of an α/β T Cell Receptor Using Alanine Scanning Mutagenesis (2000) (20)
An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry. (2016) (20)
Idiotypic analysis of monoclonal anti-fluorescyl antibodies: localization and characterization of idiotypic determinants. (1983) (20)
Recurrence of Intracranial Tumors following Adoptive T Cell Therapy Can Be Prevented by Direct and Indirect Killing Aided by High Levels of Tumor Antigen Cross-Presented on Stromal Cells1 (2009) (19)
Monoclonal IgM antibody exhibiting high-affinity binding and cryoglobulin properties. (1983) (18)
Role of CD8 in staphylococcal enterotoxin B-mediated lysis by cytotoxic T lymphocytes. (1993) (18)
Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors (2008) (17)
Novel Platform for the Detection of Staphylococcus aureus Enterotoxin B in Foods (2012) (17)
Analysis of T cell receptor transcripts using the polymerase chain reaction. (1989) (17)
Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes. (2013) (17)
Staphylococcus aureus Isolates Encode Variant Staphylococcal Enterotoxin B Proteins That Are Diverse in Superantigenicity and Lethality (2012) (17)
Kinetics and mechanism of deuterium oxide-induced fluorescence enhancement of fluorescyl ligand bound to specific heterogeneous and homogeneous antibodies. (1981) (17)
Targeting tumor cells with bispecific antibodies and T cells. (1998) (17)
Mitigation of SARS-CoV-2 transmission at a large public university (2021) (17)
A Single, Engineered Protein Therapeutic Agent Neutralizes Exotoxins from Both Staphylococcus aureus and Streptococcus pyogenes (2010) (16)
Incompatible differences: view of an allogeneic pMHC-TCR complex (2000) (16)
Opposite Effects of Endogenous Peptide–MHC Class I on T Cell Activity in the Presence and Absence of CD8 (2011) (16)
T Cell Receptor Engineering and Analysis Using the Yeast Display Platform. (2015) (16)
Affinity maturation of NZB and BALB/cV mice anti-fluorescyl response. (1982) (16)
Limited diversity of the rearranged T-cell gamma gene. (1985) (15)
The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes (2003) (15)
Intracerebral bispecific ligand‐antibody conjugate increases survival of animals bearing endogenously arising brain tumors (1998) (15)
Cellular uptake followed by class I MHC presentation of some exogenous peptides contributes to T cell stimulatory capacity. (2007) (14)
Reactivity and epitope mapping of single-chain T cell receptors with monoclonal antibodies. (1996) (13)
Recent advances in T-cell engineering for use in immunotherapy (2016) (13)
Allogeneic and syngeneic class I MHC complexes drive the association of CD8 and TCR on 2C T cells. (2003) (13)
Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell. (2019) (13)
Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens (2014) (12)
Expression of defined idiotypes throughout the BALB/c anti-fluorescyl antibody response: affinity and idiotype analyses of heterogeneous antibodies. (1983) (12)
Cutting Edge: Inhibitory Effects of CD4 and CD8 on T Cell Activation Induced by High-Affinity Noncognate Ligands1 (2009) (12)
Diversity of T cell receptor-alpha chain transcripts from hyperimmune alloreactive T cells. (1992) (11)
Characterization of transcripts from unrearranged V alpha 8 genes in the thymus. (1993) (11)
Properties of bispecific single chain antibodies expressed in Escherichia coli. (1995) (11)
Sequence restrictions in T cell receptor beta-chains that have specificity for a self-peptide/Ld complex. (1994) (10)
Multiple cancer-specific antigens are targeted by a chimeric antibody receptor on a single cancer cell. (2019) (9)
Recognition and lysis of target cells by cytotoxic T lymphocytes. (1987) (9)
T-cell Receptors Engineered De Novo for Peptide Specificity Can Mediate Optimal T-cell Activity without Self Cross-Reactivity (2019) (8)
Positive and negative selection of T lymphocytes. (1989) (7)
Expression of structurally diverse Qa-2-encoded molecules on the surface of cloned cytotoxic T lymphocytes (1984) (7)
Molecular basis of a million-fold affinity maturation process in a protein-protein interaction. (2011) (7)
Enhancing Antitumor Immunity: Combining IL-12 With TGFβ1 Antagonism (2007) (7)
Detection of lipopolysaccharide components in isolated outer membranes of Serratia marcescens (1976) (7)
Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells. (2013) (7)
A conjugate of a tumor-targeting ligand and a T cell costimulatory antibody to treat brain tumors. (2004) (6)
Sequence diversity of T cell receptor α chain transcripts from BALB/c thymus (1992) (6)
Characterization of the Staphylococcal enterotoxin A: Vβ receptor interaction using human receptor fragments engineered for high affinity. (2013) (5)
Two mechanisms that account for major histocompatibility complex restriction of T cells (2009) (5)
Faculty Opinions recommendation of CD169-positive macrophages dominate antitumor immunity by crosspresenting dead cell-associated antigens. (2011) (5)
Breaking tolerance with engineered class I antigen-presenting molecules (2019) (5)
A Multiplex Assay for Detection of Staphylococcal and Streptococcal Exotoxins (2015) (5)
Programmed cell death signaling via cell-surface expression of a single-chain antibody transgene. (2000) (5)
The Same Major Histocompatibility Complex Polymorphism Involved in Control of HIV Influences Peptide Binding in the Mouse H-2Ld System* (2013) (5)
An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes. (2020) (5)
The effect of polymyxin B on outer membrane of Serratia marcescens: activation and dissociation of outer membrane associated alkaline phosphatase. (1977) (5)
Structural basis of T cell specificity and activation by the bacterial superantigen toxic shock syndrome toxin-1 (2007) (4)
A strategy for the synthesis and screening of thiol-modified peptide variants recognized by T cells. (1996) (4)
A functional gamma gene formed from known gamma-gene segments is not necessary for antigen-specific responses of murine cytotoxic T lymphocytes. (1986) (3)
Binding of TCR Multimers and a TCR-Like Antibody with Distinct Fine-Specificities Is Dependent on the Surface Density of HLA Complexes (2012) (3)
Multiprocessor Address Tracing and Performance Analysis (1991) (3)
αβ T-Cell Receptor Repertoires Among Cytotoxic and Helper T Lymphocytes (1993) (3)
T cell receptor rearrangements in various S49 lymphoma sublines. (1992) (3)
Imaging membrane intercalating near infrared dyes to track multiple cell populations. (2009) (3)
Addressing Partitioned Arrays in Distributed Memory Multiprocessors – the Software Virtual Memory Approach (1998) (3)
T cell receptor CDRs: starring versus supporting roles (2005) (3)
A phosphorylated, disulfide-linked membrane protein in murine cytotoxic T lymphocytes. (1986) (2)
Resistance of cytolytic T lymphocytes to the lytic components they release. (1987) (2)
Long-term Persistence of CD4+ but Rapid Disappearance of CD8+ T Cells Expressing an MHC Class I-restricted TCR of Nanomolar Affinity. (2012) (2)
Faculty Opinions recommendation of Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. (2016) (2)
Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic Targeting (2012) (2)
Effect of saline on the releasability of alkaline phosphatase from cells of Serratia marcescens. (1976) (2)
Studies of the TLR4-associated protein MD-2 using yeast-display and mutational analyses. (2015) (2)
Sequence diversity of T cell receptor alpha chain transcripts from BALB/c thymus. (1991) (1)
Faculty Opinions recommendation of Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. (2007) (1)
Directed evolution of T-cell receptors for binding superantigens. (2003) (1)
Faculty Opinions recommendation of Early immunization induces persistent tumor-infiltrating CD8+ T cells against an immunodominant epitope and promotes lifelong control of pancreatic tumor progression in SV40 tumor antigen transgenic mice. (2006) (1)
This information is current as High-Affinity Noncognate Ligands CD 8 on T Cell Activation Induced by Cutting Edge : Inhibitory Effects of CD 4 and and (2009) (1)
Interaction of Streptavidin-Based Peptide-MHC Oligomers (Tetramers) with Cell-Surface T Cell Receptors (2011) (1)
Faculty Opinions recommendation of Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation. (2016) (1)
T Cell Receptors for Gene Transfer in Adoptive T Cell Therapy. (2019) (1)
Correction: selection of variable-joining region combinations in the T cell receptor. (1989) (1)
Alkaline phosphatases from clinical and non clinical strains of Serratia marcescens grown in two types of media (1975) (1)
Construction of a single-chain antibody derived from 5H7, a monoclonal antibody specific for a death signaling domain of human class I major histocompatibility complex. (1998) (1)
ResponsivenessAntigen Presentation Format on T Cell The Impact of TCR-Binding Properties and (2009) (1)
Abstract PR12: Early TCRα expression during T cell development for the generation of enhanced-affinity TCRs for TCR gene therapy. (2013) (0)
Stromal Cells Levels of Tumor Antigen Cross-Presented on by Direct and Indirect Killing Aided by High Adoptive T Cell Therapy Can Be Prevented Recurrence of Intracranial Tumors following (2009) (0)
Construction and characterization of a single chain antibody that binds a superpotent sweetener ligand (1996) (0)
Analysis of superantigen binding to soluble T-cell receptors. (2003) (0)
Engineering T cell receptors for potential therapeutic applications (48.28) (2007) (0)
Thermodynamic Properties of Antifluorescyl Antibodies (1989) (0)
Interleukin-15 (IL-15) and IL-15 receptor alpha fusion protein enhances antitumor activity of myxoma virus (2013) (0)
Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant (2006) (0)
Presenting proteins on the surface of yeast cells and their uses (1999) (0)
42F3 p5E8/H2-Ld complex (2011) (0)
Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain (2006) (0)
Faculty Opinions recommendation of 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. (2007) (0)
This information is current as Recognition Domains Human TCRs and CARs That Use the Same Comparison of T Cell Activities Mediated by (2017) (0)
Examining the role of T cell co-receptors CD4 and CD8 in T cell activation by using high-affinity T cell receptors (121.28) (2012) (0)
Mechanisms that generate junctional diversity in alpha and delta chains that use the Tcrd-V3 gene product. (1992) (0)
Erratum: Reactivity and epitope mapping of single chain T cell receptors with monoclonal antibodies (Molecular Immunology (1996) 33 (253- 263)) (1996) (0)
Faculty Opinions recommendation of Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes. (2008) (0)
Multiple thermodynamic mechanisms contribute to the binding of pepMHC ligands by wild type and high-affinity TCRs (93.16) (2007) (0)
Comparison of affinity purification techniques for single chain antibody NC 6.8 (1996) (0)
Positive and Negative Selection of T Cells: A Transgenic Model (1989) (0)
Long-term inhibition of tumor growth by T cells targeting cancer stroma alone: persistent elimination of tumor-promoting myeloid suppressor cells (2007) (0)
Crystal Structure of the G17E/A52V/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain (2006) (0)
EXPRESSION OF A GPI-ANCHORED, SINGLE-CHAIN ANTIBODY SPECIFIC FOR A CELL DEATH SIGNALING DOMAIN OF HUMAN CLASS I MHC (1998) (0)
T-cell receptor 6-chain diversity in peripheral lymphocytes ( antigen recognition / thyniic development / N regions / polymerase chain reaction ) (0)
Analysis of T cell receptor transports using the polymerase chain reaction (1989) (0)
Abstract IA1: T cells vs. tumor cells: Arming/deploying T cells for a successful battle. (2013) (0)
High affinity t-cell receptor proteins and methods (2000) (0)
Energetic Impact of Individual Peptide Residues on Binding by High-Affinity TCRs: Implications for Antigen Specificity (93.17) (2007) (0)
Engineered T cells as reagents to understand and overcome the limitations of naturally- or vaccine-induced T-cell responses (2003) (0)
Tertiary and quaternary structure of the T cell receptor α β chain dimer (1985) (0)
Mechanisms that generate junctional diversity in α and δ chains that use the Tcrd-V3 gene product (2004) (0)
Identification of peptide and T cell receptor residues involved in the interaction of CTL 2C and QL9/Ld (1996) (0)
Faculty Opinions recommendation of A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire. (2009) (0)
Faculty Opinions recommendation of Target antigen density governs the efficacy of anti-CD20-CD28-CD3 ζ chimeric antigen receptor-modified effector CD8+ T cells. (2016) (0)
Tumor-promoting stroma impregnated by cancer cells is destroyed by specific T cells (2008) (0)
Faculty Opinions recommendation of An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires. (2006) (0)
CTLA-4 (CD152) Surface-Linked Single-Chain Antibody to Blockade of T Cell Activation Using a (2000) (0)
T cells use rafts for survival. (2010) (0)
Abstract 3238: Engineering chimeric antigen receptors for adoptive T cell therapy of cancers that express the Tn antigen (2020) (0)
Tar geting the Cancer-AssociatedTn-Glycoformof theMembraneMucinMUC 1 Control Adenocarcinoma Highlights (2016) (0)
The MIT alewife machine : Distributed shared memory systems (1999) (0)
Faculty Opinions recommendation of Tuning sensitivity of CAR to EGFR density limits recognition of normal tissue while maintaining potent antitumor activity. (2016) (0)
Abstract 3581: Convergence of the specificity and cross-reactivity of multiple T cell receptors isolated against a single cancer peptide/HLA complex (2018) (0)
Faculty Opinions recommendation of The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants. (2011) (0)
Engineering T Cell Receptors for Optimal Affinities and Desired Specificities (2015) (0)
Faculty Opinions recommendation of Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing. (2012) (0)
Absence of CD8 Class I on T Cell Activity in the Presence and MHC - Opposite Effects of Endogenous Peptide (2011) (0)
Gærcelleoverfladeprotein display and uses thereof (1999) (0)
Faculty Opinions recommendation of Direct activation of antigen-presenting cells is required for CD8+ T-cell priming and tumor vaccination. (2011) (0)
A method for sensitizing a target cell by cytotoxic T lymph for analyzes. (1985) (0)
A phosphorylated, disulfide-linked membraneprotein inmurine cytotoxic Tlymphocytes (interleukin 2/fetal thymocyte/cAMP-dependent kinase/T-celi '"ygene") (1986) (0)
Determination of the role of aromatic residues in the binding pocket of an antibody that binds a sweetener lioand (1996) (0)
Investigating Structural Drivers of Antigen Specificity (2017) (0)
Faculty Opinions recommendation of Antibody buffering in the brain. (2006) (0)
Faculty Opinions recommendation of Transgenic mice with a diverse human T cell antigen receptor repertoire. (2010) (0)
Structure, Function, and Diversity of Monoclonal Anti-Fluorescyl Antibodies (1982) (0)
Crystal Structure of the S54N variant of murine T cell receptor Vbeta 8.2 domain (2006) (0)
Decision letter: Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity (2020) (0)
Erratum: Selection of variable-joining [VJ] region combinations in the α chain of the T cell receptor (Science (1988) 241 (1354)) (1989) (0)
Herman N. Eisen: Mentor to many (2015) (0)
CELL-MEDIATED DELIVERY OF PROGRAMMED CELL DEATH SIGNALS FOLLOWING GENE TRANSFER OF A MEMBRANE-ANCHORED SINGLE-CHAIN ANTIBODY SPECIFIC FOR CLASS I MHC (1999) (0)

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