David M. Ornitz
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Developmental Biology researcher
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(Suggest an Edit or Addition)David M. Ornitz's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor (1991) (2343)
- Fibroblast growth factors (2001) (2216)
- Receptor Specificity of the Fibroblast Growth Factor Family* (1996) (2053)
- The Fibroblast Growth Factor signaling pathway (2015) (1386)
- Evolution of the Fgf and Fgfr gene families. (2004) (1041)
- Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers (2012) (890)
- FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. (2002) (889)
- Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3 (1996) (858)
- FGFs, heparan sulfate and FGFRs: complex interactions essential for development. (2000) (772)
- Murine FGFR-1 is required for early postimplantation growth and axial organization. (1994) (766)
- Sequential roles of Hedgehog and Wnt signaling in osteoblast development (2004) (676)
- A twist code determines the onset of osteoblast differentiation. (2004) (670)
- Receptor Specificity of the Fibroblast Growth Factor Family (2006) (631)
- Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells (1992) (621)
- Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease. (2011) (615)
- Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth (2003) (609)
- Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. (1998) (564)
- Male-to-Female Sex Reversal in Mice Lacking Fibroblast Growth Factor 9 (2001) (560)
- Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart (2014) (530)
- Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia (1996) (499)
- Development of the endochondral skeleton. (2013) (479)
- Vertebrate Slit, a Secreted Ligand for the Transmembrane Protein Roundabout, Is a Repellent for Olfactory Bulb Axons (1999) (468)
- Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation. (2002) (466)
- Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. (2002) (463)
- Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis. (1993) (461)
- Conserved Roles for Slit and Robo Proteins in Midline Commissural Axon Guidance (2004) (445)
- Twist Regulates Cytokine Gene Expression through a Negative Feedback Loop that Represses NF-κB Activity (2003) (425)
- Functional evolutionary history of the mouse Fgf gene family (2008) (393)
- Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. (1998) (391)
- An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. (1987) (388)
- Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. (2005) (375)
- Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2 (1998) (340)
- FGF signaling in the developing endochondral skeleton. (2005) (337)
- Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme. (2001) (327)
- The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance. (1999) (307)
- Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation. (2005) (291)
- Fibroblast growth factor signaling in skeletal development and disease (2015) (286)
- Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1. (1994) (282)
- FGF22 and Its Close Relatives Are Presynaptic Organizing Molecules in the Mammalian Brain (2004) (278)
- Temporal and spatial gradients of Fgf8 and Fgf17 regulate proliferation and differentiation of midline cerebellar structures. (2000) (270)
- Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice (1987) (270)
- Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination (2004) (258)
- FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man. (2012) (257)
- Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. (2006) (246)
- Fibroblast Growth Factor (FGF) Homologous Factors Share Structural but Not Functional Homology with FGFs* (2003) (244)
- Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding (2013) (233)
- Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3. (1992) (233)
- Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. (1987) (228)
- Expression and function of FGF10 in mammalian inner ear development (2003) (227)
- Fibroblast Growth Factor Homologous Factors Control Neuronal Excitability through Modulation of Voltage-Gated Sodium Channels (2007) (223)
- Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene (1999) (221)
- FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development. (1995) (221)
- FGF signaling in skeletal development. (1998) (219)
- FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains (2006) (208)
- Analysis of the biochemical mechanisms for the endocrine actions of fibroblast growth factor-23. (2005) (208)
- Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome (2001) (207)
- Specific expression of an elastase–human growth hormone fusion gene in pancreatic acinar cells of transgenic mice (1985) (205)
- FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms. (2017) (204)
- Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements. (1991) (203)
- Abnormalities in cartilage and bone development in the Apert syndrome FGFR2+/S252W mouse (2005) (185)
- Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. (2006) (184)
- FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. (2007) (184)
- Osx-Cre Targets Multiple Cell Types besides Osteoblast Lineage in Postnatal Mice (2014) (169)
- Fibroblast growth factor 14 is an intracellular modulator of voltage‐gated sodium channels (2005) (167)
- Fgfr3 expression by astrocytes and their precursors: evidence that astrocytes and oligodendrocytes originate in distinct neuroepithelial domains (2003) (166)
- Ataxia and Paroxysmal Dyskinesia in Mice Lacking Axonally Transported FGF14 (2002) (162)
- Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. (2008) (160)
- Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. (2006) (153)
- FGF signalling generates ventral telencephalic cells independently of SHH (2006) (151)
- A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3 (2003) (142)
- Achondroplasia: Development, pathogenesis, and therapy (2017) (142)
- FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. (2007) (135)
- The FGF14F145S Mutation Disrupts the Interaction of FGF14 with Voltage-Gated Na+ Channels and Impairs Neuronal Excitability (2007) (133)
- Defective bone mineralization and osteopenia in young adult FGFR3-/- mice. (2003) (133)
- FGF9 and SHH regulate mesenchymal Vegfa expression and development of the pulmonary capillary network (2007) (132)
- Patterning the optic neuroepithelium by FGF signaling and Ras activation. (2001) (130)
- Otoconin-90, the mammalian otoconial matrix protein, contains two domains of homology to secretory phospholipase A2. (1998) (126)
- An FGF-WNT gene regulatory network controls lung mesenchyme development. (2008) (123)
- FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis (2008) (123)
- Genomic structure, mapping, activity and expression of fibroblast growth factor 17 (1999) (122)
- Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains. (2001) (120)
- Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels* (2009) (118)
- Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis (2010) (117)
- Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice. (2008) (115)
- FGF9 monomer/dimer equilibrium regulates extracellular matrix affinity and tissue diffusion (2009) (114)
- Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. (2013) (111)
- Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis (2014) (109)
- Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. (2003) (107)
- FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels (2009) (106)
- Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation (2006) (105)
- Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development (2011) (104)
- Expression of LIF in transgenic mice results in altered thymic epithelium and apparent interconversion of thymic and lymph node morphologies. (1994) (101)
- Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio. (2004) (101)
- Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis (2007) (100)
- Differentiation of the Lateral Compartment of the Cochlea Requires a Temporally Restricted FGF20 Signal (2012) (99)
- FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons (2009) (99)
- Elastase I promoter directs expression of human growth hormone and SV40 T antigen genes to pancreatic acinar cells in transgenic mice. (1985) (99)
- Fibroblast growth factor expression during skeletal fracture healing in mice (2009) (98)
- Fibroblast Growth Factor Receptor 3 Signaling Regulates the Onset of Oligodendrocyte Terminal Differentiation (2003) (97)
- Fibroblast Growth Factor Receptors Cooperate to Regulate Neural Progenitor Properties in the Developing Midbrain and Hindbrain (2007) (97)
- Development and Maintenance of Otoconia (2001) (97)
- Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development. (2016) (96)
- Expression and Biological Activity of Mouse Fibroblast Growth Factor-9 (*) (1996) (95)
- FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium (2011) (93)
- Regulation of Osteocalcin Gene Expression by a Novel Ku Antigen Transcription Factor Complex* (2002) (93)
- Mixing model systems: Using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development (2006) (91)
- Heparin-induced Self-association of Fibroblast Growth Factor-2 (1997) (91)
- FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin (2012) (91)
- The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice (1987) (91)
- Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling (2012) (88)
- Subcellular and developmental expression of alternatively spliced forms of fibroblast growth factor 14 (2000) (87)
- Otoconial agenesis in tilted mutant mice (1998) (86)
- Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14 (2007) (86)
- Stat1 Controls Postnatal Bone Formation by Regulating Fibroblast Growth Factor Signaling in Osteoblasts* (2004) (85)
- Hedgehog signaling to distinct cell types differentially regulates coronary artery and vein development (2008) (83)
- Heparan and chondroitin sulfate on growth plate perlecan mediate binding and delivery of FGF-2 to FGF receptors. (2007) (82)
- Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions. (2004) (81)
- Transplanted Oligodendrocyte Progenitor Cells Expressing a Dominant-Negative FGF Receptor Transgene Fail to Migrate In Vivo (1997) (80)
- Mapping Ligand Binding Domains in Chimeric Fibroblast Growth Factor Receptor Molecules (1999) (80)
- Fgf9 signaling regulates small intestinal elongation and mesenchymal development (2008) (79)
- Fibroblast growth factor 2 is required for epithelial recovery, but not for pulmonary fibrosis, in response to bleomycin. (2015) (74)
- Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound. (1997) (74)
- Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate (2010) (74)
- Identification of the Cytoplasmic Regions of Fibroblast Growth Factor (FGF) Receptor 1 Which Play Important Roles in Induction of Neurite Outgrowth in PC12 Cells by FGF-1 (1998) (74)
- FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands (2014) (73)
- Overlapping Expression and Redundant Activation of Mesenchymal Fibroblast Growth Factor (FGF) Receptors by Alternatively Spliced FGF-8 Ligands* (1997) (73)
- Reciprocal epithelial-mesenchymal FGF signaling is required for cecal development (2006) (72)
- Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14 (2007) (72)
- Signaling through FGF receptor‐2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation (2005) (70)
- Signalling by fibroblast growth factor receptor 3 and parathyroid hormone-related peptide coordinate cartilage and bone development. (2004) (70)
- Signaling networks regulating development of the lower respiratory tract. (2012) (70)
- MMTV-Fgf8 transgenic mice develop mammary and salivary gland neoplasia and ovarian stromal hyperplasia (1998) (69)
- Expression of FGFR3 with the G380R Achondroplasia Mutation Inhibits Proliferation and Maturation of CFK2 Chondrocytic Cells (2000) (68)
- Development and maintenance of otoconia: biochemical considerations. (2001) (67)
- Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent. (2019) (65)
- Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling (2015) (62)
- Sulfated Hydrogel Matrices Direct Mitogenicity and Maintenance of Chondrocyte Phenotype through Activation of FGF Signaling (2016) (62)
- Benign prostatic hyperplasia in a transgenic mouse: a new hormonally sensitive investigatory model. (1993) (59)
- Brain tumours and lymphomas in transgenic mice that carry HTLV-I LTR/c-myc and Ig/tax genes. (1992) (59)
- Uncoupling fibroblast growth factor receptor 2 ligand binding specificity leads to Apert syndrome-like phenotypes (2001) (58)
- Fibroblast growth factor 2 decreases bleomycin‐induced pulmonary fibrosis and inhibits fibroblast collagen production and myofibroblast differentiation (2018) (58)
- Receptor Binding and Mitogenic Properties of Mouse Fibroblast Growth Factor 3 (1995) (58)
- Regulation of the Fibroblast Growth Factor Receptor 3 Promoter and Intron I Enhancer by Sp1 Family Transcription Factors* (1998) (56)
- Shared circuitry: developmental signaling cascades regulate both embryonic and adult coronary vasculature. (2009) (55)
- Delineating a Conserved Genetic Cassette Promoting Outgrowth of Body Appendages (2013) (53)
- Histomorphological study of palatal shelf elevation during murine secondary palate formation (2011) (53)
- FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth (2016) (52)
- Fibroblast growth factors and Hedgehogs: at the heart of the epicardial signaling center. (2008) (52)
- Inhibition or Activation of Apert Syndrome FGFR2 (S252W) Signaling by Specific Glycosaminoglycans* (2006) (52)
- Microscale analysis of proteins in inner ear tissues and fluids with emphasis on endolymphatic sac, otoconia, and organ of Corti (2006) (50)
- Intracellular FGF14 (iFGF14) Is Required for Spontaneous and Evoked Firing in Cerebellar Purkinje Neurons and for Motor Coordination and Balance (2015) (50)
- Healing of non-displaced fractures produced by fatigue loading of the mouse ulna. (2010) (49)
- Rapid induction of lung adenocarcinoma by fibroblast growth factor 9 signaling through FGF receptor 3. (2013) (48)
- Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2 (2016) (48)
- Homodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular Matrix (2009) (47)
- β-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1 (2010) (47)
- Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling (2017) (46)
- FGF receptors 1 and 2 control chemically induced injury and compound detoxification in regenerating livers of mice. (2010) (45)
- Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. (2010) (45)
- A model for the pharmacological treatment of crouzon syndrome. (2006) (45)
- Identification and characterization of a novel member of the fibroblast growth factor family (1998) (45)
- A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development. (2016) (44)
- FGF14 localization and organization of the axon initial segment (2013) (43)
- Endothelial fibroblast growth factor receptor signaling is required for vascular remodeling following cardiac ischemia-reperfusion injury. (2016) (43)
- Regulation of chondrocyte growth and differentiation by fibroblast growth factor receptor 3. (2001) (39)
- Otopetrin 1 activation by purinergic nucleotides regulates intracellular calcium (2007) (39)
- Fibroblast Growth Factor Receptor 1 Signaling in Adult Cardiomyocytes Increases Contractility and Results in a Hypertrophic Cardiomyopathy (2013) (39)
- Effect of FGF/FGFR pathway blocking on lung adenocarcinoma and its cancer‐associated fibroblasts (2019) (38)
- Int-2, an autocrine and/or ultra-short-range effector in transgenic mammary tissue transplants. (1992) (36)
- The Fibroblast Growth Factor Receptor-1 Is Necessary for the Induction of Neurite Outgrowth in PC12 Cells by aFGF (1996) (35)
- Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma (2015) (35)
- Rebuilding the coronary vasculature: hedgehog as a new candidate for pharmacologic revascularization. (2007) (33)
- Fibroblast growth factor 2 is an essential cardioprotective factor in a closed‐chest model of cardiac ischemia‐reperfusion injury (2015) (31)
- Fibroblast growth factors in skeletal development. (2019) (31)
- Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancers (1987) (30)
- Identification of the Otopetrin Domain, a conserved domain in vertebrate otopetrins and invertebrate otopetrin-like family members (2008) (30)
- Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival (2016) (29)
- Missense mutations in Otopetrin 1 affect subcellular localization and inhibition of purinergic signaling in vestibular supporting cells (2011) (27)
- In Vitro Calcite Crystal Morphology Is Modulated by Otoconial Proteins Otolin-1 and Otoconin-90 (2014) (26)
- New developments in the biology of fibroblast growth factors. (2022) (25)
- FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching (2020) (25)
- Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development (2015) (24)
- OVOL2 is a critical regulator of ER71/ETV2 in generating FLK1+, hematopoietic, and endothelial cells from embryonic stem cells. (2014) (24)
- Characterization of the cell of origin and propagation potential of the fibroblast growth factor 9‐induced mouse model of lung adenocarcinoma (2015) (23)
- Identification of a FGF18-expressing alveolar myofibroblast that is developmentally cleared during alveologenesis (2019) (22)
- Novel tool to suppress cell proliferation in vivo demonstrates that myocardial and coronary vascular growth represent distinct developmental programs (2008) (22)
- Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation (2015) (21)
- FGF2-induced STAT3 activation regulates pathologic neovascularization. (2019) (21)
- FGFR2 is Required for AEC2 Homeostasis and Survival Following Bleomycin-Induced Lung Injury. (2019) (20)
- Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1) (2018) (20)
- Tumor associated macrophages support the growth of FGF9-induced lung adenocarcinoma by multiple mechanisms. (2018) (20)
- In vitro effects of recombinant otoconin 90 upon calcite crystal growth. Significance of tertiary structure (2010) (19)
- FGF20-Expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Underlying Turbinate Growth to Optimize Surface Area. (2018) (18)
- Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/F1 (1994) (18)
- β-Catenin is required for radial cell patterning and identity in the developing mouse cochlea (2019) (17)
- Generation and validation of novel conditional flox and inducible Cre alleles targeting fibroblast growth factor 18 (Fgf18) (2019) (17)
- Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty (2017) (17)
- Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody (2016) (17)
- Fibroblast Growth Factor Receptor 3 Gene Transcription Is Suppressed by Cyclic Adenosine 3′,5′-Monophosphate (1999) (17)
- Dual Transgene Expression in Murine Cerebellar Purkinje Neurons by Viral Transduction In Vivo (2014) (16)
- Lineage-specific evolution of the vertebrate Otopetrin gene family revealed by comparative genomic analyses (2011) (16)
- Tissue‐specific Expression of Pancreatic Genes in Transgenic Mice a (1986) (16)
- Osteocyte death and bone overgrowth in mice lacking Fibroblast Growth Factor Receptors 1 and 2 in mature osteoblasts and osteocytes (2018) (15)
- Role of Fgf receptor 2c in adipocyte hypertrophy in mesenteric white adipose tissue (2008) (15)
- Molecular mechanisms underlying ectopic otoconia-like particles in the endolymphatic sac of embryonic mice (2004) (15)
- Physical mapping of the mouse tilted locus identifies an association between human deafness loci DFNA6/14 and vestibular system development. (2001) (14)
- Characterisation of endogenous players in fibroblast growth factor‐regulated functions of hypothalamic tanycytes and energy‐balance nuclei (2019) (14)
- Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application. (2016) (14)
- Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner (2018) (13)
- Sculpting the skull through neurosensory epithelial–mesenchymal signaling (2018) (12)
- Determination of fibroblast growth factor receptor expression in mouse, rat and human samples using a single primer pair. (1997) (12)
- Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice (2016) (12)
- Synthesis and Fibroblast Growth Factor Binding of Oligosaccharides Related to Heparin and Heparan Sulphate (1995) (11)
- FGFR2 Is Required for AEC2 Homeostasis and Survival after Bleomycin-induced Lung Injury (2020) (11)
- Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development (2019) (11)
- Different FGFR Genes Play an Essential but Redundant Role in Post-Induction Lens Development (2003) (10)
- Diagnosis and Pathophysiological Mechanisms of Group 3 Hypoxia-Induced Pulmonary Hypertension (2019) (10)
- The FGF ligand–receptor signaling system in chondrogenesis, osteogenesis and vascularization of the endochondral skeleton (2007) (9)
- Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer. (2016) (9)
- Proteomic analysis of native cerebellar iFGF14 complexes (2016) (9)
- A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5. (2000) (8)
- Correction for Lavine et al., Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart (2016) (7)
- Endothelial FGF signaling is protective in hypoxia-induced pulmonary hypertension. (2021) (7)
- FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling (2020) (7)
- FGF20‐FGFR1 signaling through MAPK and PI3K controls sensory progenitor differentiation in the organ of Corti (2020) (6)
- Mammary Morphogenesis and Oncogenes (1992) (6)
- ETV4 and ETV5 drive synovial sarcoma through cell cycle and DUX4 embryonic pathway control (2021) (5)
- Mapping the mouse otoconin-90 (Oc90) gene to chromosome 15. (1999) (5)
- The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall (2020) (4)
- FGF 22 and Its Close Relatives Are Presynaptic Organizing Molecules in the Mammalian Brain apses (2004) (4)
- Crouzon syndrome mouse model exhibits cartilage hyperproliferation and defective segmentation in the developing trachea (2019) (4)
- Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes (2019) (4)
- The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall. (2020) (4)
- ENDOTHELIAL FIBROBLAST GROWTH FACTORS PROTECT AGAINST GROUP 3 HYPOXIA INDUCED PULMONARY HYPERTENSION (2019) (3)
- Endothelial Blood-Bone Marrow-Barrier Dynamically Regulates Balanced Stem and Progenitor Cell Trafficking and Maintenance (2012) (3)
- Digenic Variants in the FGF21 Signaling Pathway Associated with Severe Insulin Resistance and Pseudoacromegaly (2020) (3)
- BK1: an FGF-responsive central nervous system-derived cell line. (1995) (3)
- Upregulation of FGF9 in Lung Adenocarcinoma Transdifferentiation to Small Cell Lung Cancer (2021) (3)
- Analysis of FGF20‐regulated genes in organ of Corti progenitors by translating ribosome affinity purification (2020) (3)
- Fibroblast Growth Factors: Evolution (2007) (3)
- Geminin is required for Hox gene regulation to pattern the developing limb (2020) (3)
- Explorer Mutations that cause osteoglophonic dysplasia define novel roles for FGFR 1 in bone elongation (2017) (3)
- ETV4/5 drive synovial sarcoma through control of the cell cycle and the DUX4 embryonic pathway. (2021) (3)
- An Introduction to the Fibroblast Growth Factors (2017) (2)
- Author response: Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling (2015) (2)
- The Epicardial Signaling Center in Development and Disease (2010) (2)
- Regenerative responses of rabbit corneal endothelial cells to stimulation by fibroblast growth factor 1 (FGF1) derivatives, TTHX1001 and TTHX1114 (2021) (2)
- Fate Before Function: Specification of the Hair Follicle Niche Occurs Prior to its Formation and Is Progenitor Dependent (2018) (2)
- Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments (2021) (2)
- bone development and human genetic disease FGF signaling pathways in endochondral and intramembranous (2002) (2)
- An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. (2016) (2)
- IMPACT OF ENDOTHELIAL FIBROBLAST GROWTH FACTORS ON PULMONARY HYPERTENSION (2017) (1)
- Regulating Gene Expression in Mammalian Cell Culture and Transgenic Mice with Yeast GAL4/UAS Control Elements (1992) (1)
- Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification (2020) (1)
- Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis (2021) (1)
- Redundant functions of Fgfr1, Fgfr2 and Fgfr3 in the development of the mid- and hindbrain (2006) (1)
- Targeted expression of cloned genes in transgenic mice. (1987) (1)
- FGF9 and FGF10 use distinct signaling pathways to direct lung epithelial specification and branching (2019) (1)
- Erratum: Determination of fibroblast growth factor receptor expression in mouse, rat and human samples using a single primer pair (BioTechniques (June, 1997) 22 (1068-1070) (1997) (1)
- Targeted Deletion of FGF Receptor-2 Identifies a Role for FGF Signaling in Lens Growth (2002) (1)
- β-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1 (2010) (1)
- 26-OR: Digenic FGFR1/KLB Variants Associated with Endocrine Specific FGF-21 Signaling Defects and Extreme Insulin Resistance (2019) (1)
- Supplemental Information Fgf 9 and FGF 20 Maintain the Stemness of Nephron Progenitors in Mice and Man (2012) (0)
- FGF20-expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Growth of Underlying Turbinates to Optimize Epithelial Surface Area (2020) (0)
- Unique interactions of fibroblast growth factor-2 with sub-populations of heparan sulfate (1997) (0)
- S116R Phosphorylation Site Mutation in Human FGF-1 Differentially Affects Mitogenic and Glucose Lowering Activities (2016) (0)
- During vertebrate embryogenesis, the neuroectoderm differentiates into neural tissues and also into non-neural tissues such as the choroid plexus in the brain and the retinal pigment epithelium in the eye. The molecular mechanisms that pattern neural and non-neural tissues (2001) (0)
- Abstract 101: Endothelial-Specific Fibroblast Growth Factor Receptor 1 and 2 Deletion Impairs Vascular Remodeling and Recovery in an In Vivo Closed-Chest Model of Cardiac Ischemia-Reperfusion Injury (2012) (0)
- Abstract 790: Hedgehog Signaling Represents a Novel Therapeutic Target for Coronary Neo-Angiogenesis and Is Essential for Embryonic Coronary Development and Maintenance of the Coronary Vasculature in the Adult (2007) (0)
- Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia. (2023) (0)
- Cardioprotection by endogenous fibroblast growth factor 2 in cardiac ischemia-reperfusion injury in vivo (2011) (0)
- Growth Factor Signaling Pathways in Lung Development and Cancer (2012) (0)
- Abstract 10: Endothelial FGF Protects Against Pulmonary Hypertension (2017) (0)
- Single Cell RNASeq of Murine Developmental Mesenchymal Populations: Alveolar Myofibroblast Progenitors and Effects of Fgf18 Deficiency (2023) (0)
- Examining the role of FGF signaling in lung branching morphogenesis (2007) (0)
- CRYSTAL STRUCTURE OF PRO253ARG APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2 (2001) (0)
- A Mouse Model For Fibroblast Growth Factor (FGF) 9-Induced Adenocarcinoma Of The Lung (2011) (0)
- Home Help Feedback Subscriptions Archive Search Table of Co (2008) (0)
- Growth factor signaling pathways in lung development and cancer (2011) (0)
- List of Contributors (2020) (0)
- WITHDRAWN: Examining the role of FGF signaling in lung branching morphogenesis (2007) (0)
- FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells (2022) (0)
- 1656-P: FGF-21 Receptor Variants Demonstrate Severe Insulin Resistance in a Mouse Model of Insulin Mediated Pseudoacromegaly (2020) (0)
- FGF20 is required for differentiation of cochlear outer hair cells and normal hearing function (2011) (0)
- Patterning of the midbrain-hindbrain (MHB) anlage depends on an ‘organizer’ activity localized at the MHB junction (2000) (0)
- Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1) (2018) (0)
- Developmental Cell A Fibroblast Growth Factor 20-expressing, Wnt-responsive progenitor populates the olfactory epithelium and regulates turbinate growth (2018) (0)
- Program/Abstract # 384FGF20 signaling regulates organ of Corti development (2009) (0)
- Developmental Cell A Fibroblast Growth Factor 20-expressing, Wnt-responsive progenitor populates the olfactory epithelium and regulates turbinate growth (2018) (0)
- Crystal structure of human FHF1b (FGF12b) (2003) (0)
- From the tilted mouse to the otopetrin gene family: Molecular insights into the development of the vestibular mechanosensory system (2008) (0)
- Sub-populations of heparan sulfate induce active and inactive dimers of fibroblast growth factor-2 (1997) (0)
- Sox2 and FGF20 define a temporal separation between specification and differentiation required for organ of Corti development (2018) (0)
- Systeme genetique binaire commandant l'expression d'un gene mutant chez un animal a genes mutants (1991) (0)
- Loss of Fgfr1 and Fgfr2 in Scleraxis-lineage cells leads to enlarged bone eminences and attachment cell death (2021) (0)
- Genetic analysis of Fgf gene function in the limb (2007) (0)
- Small Vessels–Big Problems: Novel Insights into Microvascular Mechanisms of Diseases Endothelial fibroblast growth factor receptor signaling is required for vascular remodeling following cardiac ischemia-reperfusion injury (2016) (0)
- MODEL FOR THE PHARMACOLOGIC TREATMENT OF CROUZON SYNDROME (2006) (0)
- The role of Fgfr2 in craniofacial development: studies from a Crouzon syndrome mouse model (2005) (0)
- Accelerated healing of corneal endothelial lesions induced by engineered FGF-1 derivatives (2016) (0)
- The epicardium comprises the outer layer of the heart and provides a source of cardiac fibroblasts , vascular smooth muscle cells and pericytes during heart development (2011) (0)
- Faculty Opinions recommendation of Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. (2005) (0)
- WITHDRAWN: Genetic analysis of Fgf gene function in the limb (2007) (0)
- Endogenous fibroblast growth factor 2 is cardioprotective in an in vivo, closed-chest, murine model of regional cardiac ischemia-reperfusion injury (2012) (0)
- Fibroblast growth factor receptor signaling in endothelium mediates post-ischemic vascular remodeling and functional recovery in an in vivo, closed-chest model of acute myocardial infarction (2012) (0)
- MAMMALIAN FGF FAMILY Growth Factor Family : THE COMPLETE Receptor Specificity of the Fibroblast Mechanisms of Signal Transduction : (2006) (0)
- Defective bone mineralization and osteopenia in young adult FGFR3 (cid:1) / (cid:1) mice (2004) (0)
- Lentiviral Etv 2 Delivery Into Ischemic Hindlimbs Results in Enhanced Blood Perfusion Recovery Accompanying Augmented Capillary Formation and Reduced Tissue Fibrosis (2015) (0)
- High-resolution mapping of tlt, a mouse mutant lacking otoconia (1999) (0)
- FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling (2020) (0)
- Fibroblast growth factor 2 affects vascular remodeling after acute myocardial infarction (2012) (0)
- Targeted Deletion of Fgf9 in Tendon Disrupts Mineralization of the Developing Enthesis (2022) (0)
- Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty (2017) (0)
- 187 EMFEndogenous Fibroblast Growth Factor 2 Protects the Heart in a Murine Model of Closed Chest Regional Ischemia-Reperfusion Injury (2011) (0)
- Coronary Vasculature Shared Circuitry : Developmental Signaling Cascades Regulate Both Embryonic and Adult (2009) (0)
- Digenic Mutations in the FGF-21 Signaling Pathway Found in an Adolescent with Extreme Insulin Resistance (2018) (0)
- Fibroblast growth factor receptor signaling in cardiomyocytes is protective in the acute phase following ischemia-reperfusion injury (2022) (0)
- Mesenchymal b-catenin regulates Tbx1 expression and causes DiGeorge-like phenotypes (2008) (0)
- Targeted expression of cloned genes to the pancreas of transgenic mice (1985) (0)
- 144-OR: Adipose Modeling of FGF21 Signaling Mutations in a Severe Insulin Resistance Syndrome (2022) (0)
- Promoter andEnhancer Elements fromtheRatElastase IGene Function Independently ofEachOtherandofHeterologous Enhancers (1987) (0)
- Abstract 2700: Intracellular FGF13 Functions as an Endogenous Regulator of Myocardial Voltage-Gated Sodium (Nav) Channels (2009) (0)
- Alveolar Epithelial Fgfr2 Signaling Is Required for Recovery from Bleomycin-Induced Injury (2019) (0)
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