David Nutt
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British psychiatrist, neuropsychopharmacologist
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Why Is David Nutt Influential?
(Suggest an Edit or Addition)According to Wikipedia, David John Nutt is an English neuropsychopharmacologist specialising in the research of drugs that affect the brain and conditions such as addiction, anxiety, and sleep. He is the chairman of Drug Science, a non-profit which he founded in 2010 to provide independent, evidence-based information on drugs. Until 2009, he was a professor at the University of Bristol heading their Psychopharmacology Unit. Since then he has been the Edmond J Safra chair in Neuropsychopharmacology at Imperial College London and director of the Neuropsychopharmacology Unit in the Division of Brain Sciences there. Nutt was a member of the Committee on Safety of Medicines, and was President of the European College of Neuropsychopharmacology.
David Nutt's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. (2006) (1274)
- Drug harms in the UK: a multicriteria decision analysis (2010) (1262)
- Development of a rational scale to assess the harm of drugs of potential misuse (2007) (1112)
- Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. (2016) (744)
- Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin (2012) (737)
- Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology (2005) (563)
- The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs (2014) (514)
- Neural correlates of the LSD experience revealed by multimodal neuroimaging (2016) (507)
- Sleep disorders as core symptoms of depression (2008) (496)
- The dopamine theory of addiction: 40 years of highs and lows (2015) (496)
- Consensus statement on generalized anxiety disorder from the International Consensus Group on Depression and Anxiety. (2001) (474)
- Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: A revision of the 2005 guidelines from the British Association for Psychopharmacology (2014) (457)
- Psilocybin with psychological support for treatment-resistant depression: six-month follow-up (2017) (431)
- Homological scaffolds of brain functional networks (2014) (430)
- Relationship of neurotransmitters to the symptoms of major depressive disorder. (2008) (390)
- Tryptophan metabolism in the central nervous system: medical implications (2006) (389)
- Amphetamine, past and present – a pharmacological and clinical perspective (2013) (380)
- Role of GABA in anxiety and depression (2004) (372)
- The other face of depression, reduced positive affect: the role of catecholamines in causation and cure (2007) (358)
- Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study. (1998) (355)
- Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression (2018) (354)
- GABA system dysfunction in autism and related disorders: From synapse to symptoms (2012) (353)
- Estimating the Harms of Nicotine-Containing Products Using the MCDA Approach (2014) (325)
- Broadband Cortical Desynchronization Underlies the Human Psychedelic State (2013) (322)
- Consensus statement on posttraumatic stress disorder from the International Consensus Group on Depression and Anxiety. (2000) (320)
- Factors influencing success of clinical genome sequencing across a broad spectrum of disorders (2015) (319)
- Trial of Psilocybin versus Escitalopram for Depression. (2021) (316)
- New insights into the role of the GABAA–benzodiazepine receptor in psychiatric disorder (2001) (311)
- Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution (2016) (300)
- Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms (2017) (297)
- Unusual interactions of benzodiazepine receptor antagonists (1982) (284)
- Tryptophan depletion and its implications for psychiatry (2001) (273)
- Enhanced repertoire of brain dynamical states during the psychedelic experience (2014) (267)
- Flumazenil provocation of panic attacks. Evidence for altered benzodiazepine receptor sensitivity in panic disorder. (1990) (265)
- The anxiogenic action of benzodiazepine antagonists (1982) (261)
- Selective serotonin reuptake inhibitors: meta‐analysis of discontinuation rates (1994) (256)
- Evidence-based guidelines for management of attention-deficit/hyperactivity disorder in adolescents in transition to adult services and in adults: recommendations from the British Association for Psychopharmacology (2007) (253)
- Patients’ Accounts of Increased “Connectedness” and “Acceptance” After Psilocybin for Treatment-Resistant Depression (2017) (251)
- Evidence-based guidelines for the pharmacological management of attention deficit hyperactivity disorder: Update on recommendations from the British Association for Psychopharmacology (2014) (248)
- Case History 3 (1997) (248)
- 'Seeing through a glass darkly': casting light on imidazoline 'I' sites. (1998) (247)
- Effects of Schedule I drug laws on neuroscience research and treatment innovation (2013) (240)
- Human tide: the real migration crisis. (2007) (238)
- A web-based survey on mephedrone. (2011) (238)
- The role of dopamine and norepinephrine in depression and antidepressant treatment. (2006) (228)
- The neuropharmacology of serotonin and noradrenaline in depression (2002) (220)
- Structural and functional brain changes in posttraumatic stress disorder. (2004) (216)
- Psychotropic Drugs, Cardiac Arrhythmia, and Sudden Death (2003) (214)
- Ethyl β-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats (1981) (213)
- LSD‐induced entropic brain activity predicts subsequent personality change (2016) (208)
- Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition (2017) (203)
- Functional connectivity measures after psilocybin inform a novel hypothesis of early psychosis. (2013) (201)
- Ego-Dissolution and Psychedelics: Validation of the Ego-Dissolution Inventory (EDI) (2016) (200)
- The paradoxical psychological effects of lysergic acid diethylamide (LSD) (2016) (192)
- Human Taste Thresholds Are Modulated by Serotonin and Noradrenaline (2006) (185)
- Defining substance use disorders: do we really need more than heavy use? (2013) (184)
- Striatal dopamine D2/D3 receptor binding in pathological gambling is correlated with mood-related impulsivity (2012) (183)
- Invited review: the evolution of antidepressant mechanisms (2004) (179)
- Association of the Anxiogenic and Alerting Effects of Caffeine with ADORA2A and ADORA1 Polymorphisms and Habitual Level of Caffeine Consumption (2010) (176)
- The size, burden and cost of disorders of the brain in the UK (2013) (172)
- Benzodiazepines: Risks and benefits. A reconsideration (2013) (172)
- Overview of Diagnosis and Drug Treatments of Anxiety Disorders (2005) (171)
- Evidence-Based Guidelines for the Pharmacological Management of Substance Misuse, Addiction and Comorbidity: Recommendations from the British Association for Psychopharmacology (2004) (171)
- The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers (2014) (170)
- Finding the self by losing the self: Neural correlates of ego‐dissolution under psilocybin (2015) (169)
- Mechanisms of action of selective serotonin reuptake inhibitors in the treatment of psychiatric disorders (1999) (168)
- Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study. (2008) (167)
- LSD enhances suggestibility in healthy volunteers (2015) (166)
- Noradrenaline and attention lapses (1996) (164)
- Psychiatry & the psychedelic drugs. Past, present & future (2017) (164)
- Which antidepressants have demonstrated superior efficacy? A review of the evidence (2007) (160)
- Stratified medicine for mental disorders (2014) (159)
- Implications for psychedelic-assisted psychotherapy: functional magnetic resonance imaging study with psilocybin. (2012) (157)
- Consensus statement update on posttraumatic stress disorder from the international consensus group on depression and anxiety. (2004) (155)
- Changes in regional cerebral blood flow elicited by craving memories in abstinent opiate-dependent subjects. (2001) (155)
- Alcoholism and panic disorder: is the comorbidity more than coincidence? (1990) (152)
- Predicting Responses to Psychedelics: A Prospective Study (2018) (150)
- Antidepressant-induced jitteriness/anxiety syndrome: systematic review (2009) (148)
- Disturbances of hypothalamic-pituitary-adrenal axis functioning during ethanol withdrawal in six men. (1991) (145)
- The effects of elevated endogenous GABA levels on movement-related network oscillations (2013) (145)
- The biological, social and clinical bases of drug addiction: commentary and debate (1996) (144)
- NIH conference. Alcohol withdrawal and noradrenergic function. (1987) (143)
- Acute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis ‘amotivational’ hypotheses (2016) (141)
- Searching for perfect sleep: the continuing evolution of GABAA receptor modulators as hypnotics (2010) (139)
- Measuring Endogenous 5-HT Release by Emission Tomography: Promises and Pitfalls (2010) (137)
- Resolution of Sleepiness and Fatigue in Major Depressive Disorder: A Comparison of Bupropion and the Selective Serotonin Reuptake Inhibitors (2006) (137)
- Clinical evidence and potential neurobiological underpinnings of unresolved symptoms of depression. (2008) (137)
- Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites--current status. (1993) (136)
- The psychobiology of anxiolytic drugs. Part 1: Basic neurobiology. (2000) (136)
- British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: An update (2019) (135)
- Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis. (2008) (135)
- Altered Central α2-Adrenoceptor Sensitivity in Panic Disorder (1989) (133)
- Acute Tryptophan Depletion. Part I: Rationale and Methodology (2005) (132)
- European rating of drug harms (2015) (132)
- Consensus statement on social anxiety disorder from the International Consensus Group on Depression and Anxiety. (1998) (131)
- 5‐HT radioligands for human brain imaging with PET and SPECT (2013) (131)
- Neural substrates of cue reactivity and craving in gambling disorder (2016) (130)
- Adenosine Receptor Subtypes Modulate Two Major Functional Pathways for Hippocampal Serotonin Release (2001) (129)
- Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling (1984) (127)
- Effects of psilocybin therapy on personality structure (2018) (127)
- Psychedelic Psychiatry’s Brave New World (2020) (125)
- GABAA receptors: subtypes, regional distribution, and function. (2006) (125)
- Is RO 15-4513 a specific alcohol antagonist? (1987) (124)
- A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature (2015) (122)
- Caffeine and Central Noradrenaline: Effects on Mood, Cognitive Performance, Eye Movements and Cardiovascular Function (2003) (122)
- Addiction: brain mechanisms and their treatment implications (1996) (120)
- European neuropsychopharmacology: The journal of the European College of Neuropsychopharmacology (2009) (120)
- Role of GABA in memory and anxiety (1996) (120)
- Correlation of subjective and objective sleep measurements at different stages of the treatment of depression (2003) (119)
- The psychobiology of anxiolytic drug. Part 2: Pharmacological treatments of anxiety. (2000) (118)
- The Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level–Dependent Resting State Functional Connectivity (2015) (118)
- Neurobiological mechanisms in generalized anxiety disorder. (2001) (118)
- Generalized anxiety disorder: comorbidity, comparative biology and treatment. (2002) (117)
- Biological markers for anxiety disorders, OCD and PTSD – a consensus statement. Part I: Neuroimaging and genetics (2016) (117)
- Ketamine treatment for depression: opportunities for clinical innovation and ethical foresight. (2017) (117)
- Blockade of alcohol's amnestic activity in humans by an α5 subtype benzodiazepine receptor inverse agonist (2007) (114)
- Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse (2015) (112)
- Gamma hydroxy butyrate abuse and dependency (2005) (112)
- Is there cognitive impairment in clinically 'healthy' abstinent alcohol dependence? (2005) (111)
- Consensus statement on transcultural issues in depression and anxiety from the International Consensus Group on Depression and Anxiety. (2001) (110)
- Consensus statement on the primary care management of depression from the International Consensus Group on Depression and Anxiety. (1999) (110)
- Behavioral and cardiovascular effects of 7.5% CO2 in human volunteers (2005) (110)
- β-carboline binding to imidazoline receptors (2001) (107)
- The hidden therapist: evidence for a central role of music in psychedelic therapy (2018) (107)
- Increased amygdala responses to emotional faces after psilocybin for treatment-resistant depression (2017) (106)
- Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study (2014) (106)
- Imaging the GABA-Benzodiazepine Receptor Subtype Containing the α5-Subunit In Vivo with [11C]Ro15 4513 Positron Emission Tomography (2002) (106)
- Innovative solutions to novel drug development in mental health (2013) (106)
- Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder. (2005) (106)
- Neural correlates of the DMT experience assessed with multivariate EEG (2019) (105)
- Orexin-A Infusion in the Locus Ceruleus Triggers Norepinephrine (NE) Release and NE-Induced Long-Term Potentiation in the Dentate Gyrus (2004) (105)
- Uncritical positive regard? Issues in the efficacy and safety of psychotherapy (2008) (104)
- Preclinical safety testing of monoclonal antibodies: the significance of species relevance (2007) (103)
- Functional Studies of Specific Imidazoline‐2 Receptor Ligands (1995) (103)
- Anhedonia revisited: Is there a role for dopamine-targeting drugs for depression? (2013) (102)
- Lactate and hyperventilation substantially attenuate vagal tone in normal volunteers. A possible mechanism of panic provocation? (1989) (101)
- Dynamical exploration of the repertoire of brain networks at rest is modulated by psilocybin (2019) (100)
- DMT Models the Near-Death Experience (2018) (99)
- Serotonin and panic (1998) (99)
- LSD enhances the emotional response to music (2015) (99)
- Decreased mental time travel to the past correlates with default-mode network disintegration under lysergic acid diethylamide (2016) (98)
- GABAB receptors in addiction and its treatment. (2010) (97)
- Inhibition of amine oxidase activity by derivatives that recognize imidazoline I2 sites. (1995) (97)
- Inhalation of 35% CO2 results in activation of the HPA axis in healthy volunteers (2002) (97)
- Neurobiology of addiction and implications for treatment (2003) (97)
- Alcohol and the brain (1999) (96)
- The pharmacology of human anxiety. (1990) (96)
- Blunted Endogenous Opioid Release Following an Oral Amphetamine Challenge in Pathological Gamblers (2015) (96)
- WCA Recommendations for the Long-Term Treatment of Generalized Anxiety Disorder (2003) (96)
- Opportunities for improving animal welfare in rodent models of epilepsy and seizures (2016) (95)
- WCA Recommendations for the Long-Term Treatment of Obsessive-Compulsive Disorder in Adults (2003) (95)
- Cytokine levels in euthymic bipolar patients. (2010) (94)
- The effect of nicotine on striatal dopamine release in man: A [11C]raclopride PET study (2007) (94)
- The brain GABA-benzodiazepine receptor alpha-5 subtype in autism spectrum disorder: A pilot [11C]Ro15-4513 positron emission tomography study (2013) (94)
- Endogenous Opioid Release in the Human Brain Reward System Induced by Acute Amphetamine Administration (2012) (94)
- Intrinsic actions of benzodiazepine antagonists (1982) (94)
- Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine (2002) (93)
- Mechanism of action of antidepressants. (2002) (92)
- Tryptophan depletion reverses the therapeutic effect of selective serotonin reuptake inhibitors in social anxiety disorder (2004) (92)
- Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies (2020) (91)
- The Current Status of Psychedelics in Psychiatry. (2020) (91)
- Consensus statement on panic disorder from the International Consensus Group on Depression and Anxiety. (1998) (91)
- Microbial infections in eight genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis (2009) (90)
- Comparison of the effects of repeated electroconvulsive shock on α2- and β-adrenoceptors in different regions of rat brain (1982) (89)
- Ethanollike properties of the serotonergic partial agonist m-chlorophenylpiperazine in chronic alcoholic patients. (1991) (88)
- Microdosing psychedelics: More questions than answers? An overview and suggestions for future research (2019) (88)
- Mourning and melancholia revisited: correspondences between principles of Freudian metapsychology and empirical findings in neuropsychiatry (2008) (87)
- ECNP Summit on the future of CNS drug research in Europe 2011: Report prepared for ECNP by David Nutt and Guy Goodwin (2011) (87)
- Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 1993 British Association for Psychopharmacology guidelines. British Association for Psychopharmacology. (2000) (86)
- The neurobiology of social phobia (1999) (84)
- Death and Dependence: Current Controversies over the Selective Serotonin Reuptake Inhibitors (2003) (83)
- A Lifetime Prevalence of Comorbidity Between Bipolar Affective Disorder and Anxiety Disorders: A Meta-analysis of 52 Interview-based Studies of Psychiatric Population (2015) (83)
- L‐Tryptophan and prolactin release: Evidence for interaction between 5‐HT1 and 5‐HT2 receptors (1986) (83)
- Brain mechanisms of social anxiety disorder. (1998) (82)
- Does the Brain Noradrenaline Network Mediate the Effects of the CO2 Challenge? (2003) (81)
- Randomised controlled study of sleep after nefazodone or paroxetine treatment in out-patients with depression. (2002) (81)
- Tolerability and safety aspects of mirtazapine (2002) (81)
- Characterisation and localisation of [3H]2-(2-benzofuranyl)-2-imidazoline binding in rat brain: a selective ligand for imidazoline I2 receptors. (1998) (80)
- Novel Selective Compounds for the Investigation of Imidazoline Receptors a (1999) (80)
- Generalized anxiety disorder: A comorbid disease (2006) (80)
- A proposal for an updated neuropsychopharmacological nomenclature (2014) (80)
- Consensus statement on depression, anxiety, and oncology. (2001) (80)
- Vienna Declaration: a call for evidence-based drug policies (2010) (80)
- Saccadic eye movement parameters in normal subjects. (1993) (79)
- A Translational Rodent Assay of Affective Biases in Depression and Antidepressant Therapy (2013) (79)
- LSD modulates music-induced imagery via changes in parahippocampal connectivity (2016) (79)
- Functional connectivity analysis of the neural circuits of opiate craving: “more” rather than “different”? (2003) (78)
- Successful Treatment of Night Terrors and Somnambulism with Paroxetine (1994) (77)
- In vivo imaging of microglial activation by positron emission tomography with [11C]PBR28 in the 5XFAD model of Alzheimer's disease (2016) (77)
- The role of the opioid system in alcohol dependence (2014) (77)
- Increased global integration in the brain after psilocybin therapy for depression (2022) (77)
- Mirtazapine: pharmacology in relation to adverse effects (1997) (76)
- Impulsiveness, serotonin genes and repetition of deliberate self-harm (DSH) (2000) (76)
- Amphetamine induced endogenous opioid release in the human brain detected with [¹¹C]carfentanil PET: replication in an independent cohort. (2014) (76)
- Role of GABA in anxiety and depression. (2007) (76)
- Does alcohol increase the risk of overdose death: the need for a translational approach. (2008) (75)
- Acute Tryptophan Depletion. Part II: Clinical Effects and Implications (2005) (74)
- User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study (2010) (74)
- Brain dopamine response in human opioid addiction (2008) (73)
- The Australian drug harms ranking study (2019) (72)
- A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers (2007) (72)
- Studies on the post-ictal rise in seizure threshold. (1981) (72)
- Apolipoprotein E genotyping in Alzheimer's disease (1996) (72)
- Cape Town consensus on posttraumatic stress disorder. (2009) (72)
- Effects of stressful life events, maternal depression and 5‐HTTLPR genotype on emotional symptoms in pre‐adolescent children (2009) (71)
- Effect of pregnancy on panic attacks. (1987) (71)
- Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge (2010) (70)
- Selective serotonin reuptake inhibitors (1994) (69)
- Substitution therapy for alcoholism: time for a reappraisal? (2012) (69)
- The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy (2002) (69)
- The hidden third: improving outcome in treatment-resistant depression (2012) (68)
- Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism (2003) (68)
- Doing it by numbers: A simple approach to reducing the harms of alcohol (2014) (68)
- Preclinical development of monoclonal antibodies (2009) (68)
- The effect of acutely administered MDMA on subjective and BOLD-fMRI responses to favourite and worst autobiographical memories. (2014) (68)
- International consensus statement on major depressive disorder. (2010) (67)
- Harms associated with psychoactive substances: findings of the UK National Drug Survey (2010) (67)
- Acute tryptophan depletion. Part II: clinical effects and implications. (2005) (67)
- Bidirectional effects of chronic treatment with agonists and inverse agonists at the benzodiazepine receptor (1987) (67)
- Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes (2007) (67)
- A Review of 3,4-methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy (2019) (67)
- Drug research: A plan for mental illness (2012) (66)
- The effect of the imidazodiazepine Ro 15-4513 on the anticonvulsant effects of diazepam, sodium pentobarbital and ethanol (1987) (66)
- A single preexposure produces sensitization to the locomotor effects of cocaine in mice (1993) (64)
- Alpha-2-adrenoceptor function in alcohol withdrawal: a pilot study of the effects of iv. clonidine in alcoholics and normals. (1988) (63)
- Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression (2009) (63)
- Effects of acute tyrosine/phenylalanine depletion on the selective processing of smoking-related cues and the relative value of cigarettes in smokers (2008) (62)
- Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression (2020) (62)
- On the measurement in rats of the convulsant effect of drugs and the changes which follow electroconvulsive shock (1980) (62)
- Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: An [11C]diprenorphine PET study (2009) (62)
- Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals (2014) (61)
- Integrating the cognitive and physiological aspects of craving (1998) (61)
- Serotonin and sleep : molecular, functional and clinical aspects (2008) (60)
- Putting the 'A' in atypical: does α2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics? (1994) (60)
- Biological markers of generalized anxiety disorder (2017) (59)
- Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial (2011) (59)
- Using [11C]Diprenorphine to Image Opioid Receptor Occupancy by Methadone in Opioid Addiction: Clinical and Preclinical Studies (2005) (59)
- Care of depressed patients with anxiety symptoms. (1999) (59)
- Treatment of anxiety and depressive disorders in patients with cardiovascular disease (2004) (59)
- Comparison of Alterations in c-fos and Egr-1 (zif268) Expression Throughout the Rat Brain Following Acute Administration of Different Classes of Antidepressant Compounds (2005) (59)
- Depleting Serotonin Enhances Both Cardiovascular and Psychological Stress Reactivity in Recovered Patients With Anxiety Disorders (2006) (58)
- Behavioral and neuroendocrine responses to m-chlorophenylpiperazine in subtypes of alcoholics and in healthy comparison subjects. (1997) (58)
- Chronic electroconvulsive shock and neurotransmitter receptors--an update. (1989) (58)
- ABSTINENCE SYMPTOMS AFTER WITHDRAWAL OF TRANQUILLISING DRUGS: IS THERE A COMMON NEUROCHEMICAL MECHANISM? (1982) (58)
- Home cage presentation of complex discrimination tasks to marmosets and rhesus monkeys (1999) (57)
- The tangible common denominator of substance use disorders: a reply to commentaries to Rehm et al. (2013a). (2014) (57)
- Cerebral blood flow predicts differential neurotransmitter activity (2017) (57)
- Generic legislation of new psychoactive drugs (2013) (57)
- History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability (2012) (57)
- WCA Recommendations for the Long-Term Treatment of Panic Disorder (2003) (56)
- Clinical pharmacology of anxiolytics and antidepressants: A psychopharmacological perspective (1989) (56)
- Self-blinding citizen science to explore psychedelic microdosing (2020) (56)
- Benzodiazepine dependence in the clinic: reason for anxiety? (1986) (54)
- A translational, caffeine-induced model of onset insomnia in rats and healthy volunteers (2007) (54)
- Psychedelic drugs—a new era in psychiatry? (2019) (54)
- [3H]2-(2-benzofuranyl)-2-imidazoline: a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors. (1996) (53)
- Preliminary evidence of anxiolytic effects of the CRF1 receptor antagonist R317573 in the 7.5% CO2 proof-of-concept experimental model of human anxiety (2011) (53)
- Alcohol: the drug. (1994) (53)
- Altered central alpha 2-adrenoceptor sensitivity in panic disorder. (1989) (53)
- Behavioral, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naive rats and rats exposed to the stress of the forced swim test (2003) (53)
- Diazepam alters brain 5-HT function in man: implications for the acute and chronic effects of benzodiazepines (1987) (53)
- In Vivo Imaging of Cerebral Dopamine D3 Receptors in Alcoholism (2014) (52)
- Distinct Neuropsychological Mechanisms May Explain Delayed- Versus Rapid-Onset Antidepressant Efficacy (2015) (52)
- The use of benzodiazepines in anxiety and other disorders (1998) (51)
- Consensus Document on European Brain Research (2011) (51)
- Circadian rhythms of cortisol during alcohol withdrawal. (1988) (50)
- Rapid induction of lorazepam dependence and reversal with flumazenil. (1988) (50)
- GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study (2005) (50)
- Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline2 Binding Site in Human Brain (2014) (50)
- Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression (2017) (50)
- Interactions of the imidazodiazepine Ro 15–4513 with chemical convulsants (1988) (50)
- Pharmacology of saccadic eye movements in man. 1. Effects of the benzodiazepine receptor ligands midazolam and flumazenil. (1991) (49)
- Platelet binding studies in panic disorder. (1987) (49)
- A benzodiazepine agonist and contragonist have hypothermic effects in rodents (1985) (49)
- A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions (2012) (48)
- Sertraline, a selective serotonin reuptake inhibitor modulates extracellular noradrenaline in the rat frontal cortex (1998) (48)
- Early onset anxiolytic efficacy after a single dose of pregabalin: double-blind, placebo- and active-comparator controlled evaluation using a dental anxiety model (2009) (48)
- Brain opioid receptor binding in early abstinence from opioid dependence: positron emission tomography study. (2007) (48)
- Consensus statement and research needs: the role of dopamine and norepinephrine in depression and antidepressant treatment. (2006) (47)
- The 5-HT3 antagonist ondansetron reduces gastrointestinal side effects induced by a specific serotonin re-uptake inhibitor in man (1995) (47)
- Panic attacks and alcohol withdrawal: Can subjects differentiate the symptoms? (1988) (47)
- Dissociable effects of cannabis with and without cannabidiol on the human brain’s resting-state functional connectivity (2019) (47)
- Understanding the Neurobiology of Comorbidity in Anxiety Disorders (2006) (47)
- Exploring δ-receptor function using the selective opioid antagonist naltrindole (1989) (47)
- Increased sympathetic response to standing in panic disorder (2003) (46)
- Clinical pharmacology of anxiolytics and antidepressants: a psychopharmacological perspective. (1989) (46)
- Pharmacology of saccadic eye movements in man (1991) (46)
- Anxiety and depression: individual entities or two sides of the same coin? (2004) (46)
- Addiction: the clinical interface (2008) (46)
- Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson's disease: an in vivo11C-BU99008 PET study. (2019) (46)
- The administration of psilocybin to healthy, hallucinogen-experienced volunteers in a mock-functional magnetic resonance imaging environment: a preliminary investigation of tolerability (2011) (45)
- Comparison of the effects of chronic desmethylimipramine administration on α2- and β-adrenoceptors in different regions of rat brain (1983) (45)
- Serotonin and Sensitivity to Trauma-Related Exposure in Selective Serotonin Reuptake Inhibitors-Recovered Posttraumatic Stress Disorder (2009) (45)
- New Governance of Addictive Substances and Behaviours (2017) (45)
- In vitro and ex vivo distribution of [3H]harmane, an endogenous β-carboline, in rat brain (2006) (44)
- Elevating Endogenous GABA Levels with GAT-1 Blockade Modulates Evoked but Not Induced Responses in Human Visual Cortex (2013) (44)
- WCA Recommendations for the Long-Term Treatment of Social Phobia (2003) (44)
- Efficacy and safety of sodium oxybate in alcohol‐dependent patients with a very high drinking risk level (2018) (44)
- Imidazoline binding sites in Huntington's and Parkinson's disease putamen. (1996) (44)
- Anti‐oxidant vitamins and mental performance of the elderly (1999) (44)
- Substance-P antagonists: a new treatment for depression? (1998) (44)
- Addiction Imaging in clinical neuroscience (2003) (43)
- Management of patients with depression associated with anxiety symptoms. (1997) (43)
- Investigation of the sleep electrocorticogram of the common marmoset (Callithrix jacchus) using radiotelemetry (2001) (43)
- Consensus document on European brain research. (2006) (43)
- Treatment of depression and concomitant anxiety (2000) (43)
- Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain (2011) (42)
- Electroconvulsive Shock (ECS) and the Adenosine Neuromodulatory System: Effect of Single and Repeated ECS on the Adenosine A1 and A2 Receptors, Adenylate Cyclase, and the Adenosine Uptake Site (1989) (42)
- Pharmacology of saccadic eye movements in man (1991) (42)
- Gender differences in brain serotonin transporter availability in panic disorder (2011) (42)
- Acute increases in synaptic GABA detectable in the living human brain: A [11C]Ro15-4513 PET study (2014) (42)
- MDMA, politics and medical research: Have we thrown the baby out with the bathwater? (2007) (42)
- Benzodiazepine Site Pharmacokinetic/Pharmacodynamic Quantification in Man: Direct Measurement of Drug Occupancy and Effects on the Human Brain In Vivo (1996) (42)
- Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis: disease mechanisms, a diagnostic test and specific treatments (2006) (42)
- Kindling and withdrawal changes at the benzodiazepine receptor (1987) (41)
- Estimating the synaptic concentration of norepinephrine in dentate gyrus which produces β-receptor mediated long-lasting potentiation in vivo using microdialysis and intracerebroventricular norepinephrine (1996) (41)
- Psychopharmacology of Repeated Seizures: Possible Relevance to the Mechanism of Action of Electroconvulsive Therapy (1987) (41)
- Antagonizing the anticonvulsant effect of ethanol using drugs acting at the benzodiazepine/GABA receptor complex (1988) (41)
- A placebo-controlled investigation of synaesthesia-like experiences under LSD (2016) (40)
- LSD alters eyes‐closed functional connectivity within the early visual cortex in a retinotopic fashion (2016) (40)
- Consensus statement on depression, anxiety, and cardiovascular disease. (2001) (40)
- Sleep changes during long-term treatment of depression with fluvoxamine – a home-based study (2000) (40)
- Naloxone displacement at opioid receptor sites measured in vivo in the human brain. (2003) (39)
- Drugs and the Future: Brain Science, Addiction and Society (2006) (39)
- Monoamines and alcohol. (1986) (39)
- Experienced Drug Users Assess the Relative Harms and Benefits of Drugs: A Web-Based Survey (2013) (39)
- A qualitative report on the subjective experience of intravenous psilocybin administered in an FMRI environment. (2015) (39)
- A non-inferiority comparison of duloxetine and venlafaxine in the treatment of adult patients with generalized anxiety disorder (2008) (39)
- Death by tricyclic: the real antidepressant scandal? (2005) (39)
- The Standard Joint Unit. (2017) (39)
- Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2‐(4,5‐Dihydro‐1H‐imidazol‐2‐yl)‐1‐ methyl‐1H‐indole), for the imidazoline2 binding site (2012) (39)
- Monoamine Oxidase Inhibitors: Rehabilitation from Recent Research? (1989) (39)
- Anxiolytic Potential of Benzodiazepine Receptor Partial Agonists (1994) (38)
- GABA-A receptor differences in schizophrenia: a positron emission tomography study using [11C]Ro154513 (2020) (38)
- Inhibition of Central Monoamine Oxidase by Imidazoline2 Site‐Selective Ligands (1999) (38)
- E-cigarettes are less harmful than smoking (2016) (38)
- LSD modulates effective connectivity and neural adaptation mechanisms in an auditory oddball paradigm (2017) (37)
- Addiction and withdrawal--current views. (2001) (37)
- Post-traumatic Stress Disorder: Diagnosis, Management and Treatment (2000) (37)
- Chronic benzodiazepine treatment increases the effects of the inverse agonist FG7142 (1988) (37)
- Consensus statement on the benefit to the community of ESEMeD (European Study of the Epidemiology of Mental Disorders) survey data on depression and anxiety. (2007) (37)
- Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome. (2010) (37)
- Harmane and harmalan are bioactive components of classical clonidine-displacing substance. (2004) (37)
- The Hamilton Depression Scale—accelerator or break on antidepressant drug discovery? (2014) (37)
- WCA Recommendations for the Long-Term Treatment of Posttraumatic Stress Disorder (2003) (37)
- Acute Tryptophan Depletion Alters Gastrointestinal and Anxiety Symptoms in Irritable Bowel Syndrome (2006) (37)
- Identification of ligands selective for central I2-imidazoline binding sites (1997) (36)
- beta-carboline binding to imidazoline receptors. (2001) (36)
- Differences between magnetoencephalographic (MEG) spectral profiles of drugs acting on GABA at synaptic and extrasynaptic sites: A study in healthy volunteers (2015) (36)
- Anxiety and Its Therapy: Today and Tomorrow (1991) (36)
- BAP Position Statement: Off-label prescribing of psychotropic medication to children and adolescents (2016) (36)
- Neuroimaging of serotonin system in anxiety disorders. (2012) (36)
- A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials (2021) (36)
- Illegal Drugs Laws: Clearing a 50-Year-Old Obstacle to Research (2015) (35)
- Loss of consciousness and post-traumatic stress disorder (1998) (35)
- The effects of chronic ritanserin treatment on sleep and the neuroendocrine response to l-tryptophan (2004) (35)
- Significant reductions in human visual gamma frequency by the gaba reuptake inhibitor tiagabine revealed by robust peak frequency estimation (2016) (35)
- Evaluation of 11C-BU99008, a PET Ligand for the Imidazoline2 Binding Sites in Rhesus Brain (2014) (34)
- Benzodiazepine receptor inverse agonists (1995) (34)
- The criteria of Cloninger et al. and von Knorring et al. for subgrouping alcoholics: a comparison in a clinical population (1991) (34)
- GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models (2018) (34)
- Using sleep to evaluate comparative serotonergic effects of paroxetine and citalopram (2004) (34)
- Adverse effects of psychedelics: From anecdotes and misinformation to systematic science (2022) (33)
- The use of sleep measures to compare a new 5HT1A agonist with buspirone in humans (2005) (33)
- The neuroendocrine effects of oral imipramine (1987) (33)
- Waiving in vivo studies for monoclonal antibody biosimilar development: National and global challenges (2016) (33)
- A cerebrospinal fluid study of the pathophysiology of panic disorder associated with alcoholism (1990) (33)
- Imagery of craving in opiate addicts undergoing detoxification. (1997) (33)
- Natural speech algorithm applied to baseline interview data can predict which patients will respond to psilocybin for treatment-resistant depression. (2018) (33)
- Carbamazepine retards the development of cocaine-kindled seizures but not sensitization to cocaine-induced hyperactivity. (1990) (33)
- Antidepressant drugs and the cardiovascular system: a comparison of tricylics and selective serotonin reuptake inhibitors and their relevance for the treatment of psychiatric patients with cardiovascular problems (1997) (33)
- Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [11C]Ro15-4513 PET images (2012) (33)
- Analysis of Dynamic Radioligand Displacement or “Activation” Studies (1997) (33)
- Assessment and management of insomnia. (2005) (33)
- Identification of an imidazoline binding protein: Creatine kinase and an imidazoline-2 binding site (2009) (32)
- Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide (1990) (32)
- Neuroscience-based Nomenclature (NbN) for Journal of Psychopharmacology (2016) (32)
- CNS drug development in Europe — Past progress and future challenges (2014) (32)
- Investigating expectation and reward in human opioid addiction with [11C]raclopride PET (2013) (32)
- Clinical Relevance of As-Needed Treatment with Nalmefene in Alcohol-Dependent Patients (2015) (32)
- A pilot controlled study of the effects of flumazenil in posttraumatic stress disorder (1997) (32)
- Studies of alpha-2-adrenoceptor function in abstinent alcoholics. (1989) (32)
- Effects of 7.5% CO2 challenge in generalized anxiety disorder (2011) (32)
- Consensus statement on depression, anxiety, and functional gastrointestinal disorders. (2001) (32)
- The use of benzodiazepines in anxiety and other disorders (1998) (32)
- The psychopharmacology of anxiety. (2004) (31)
- Attenuation of ethanol intoxication by alpha-2 adrenoceptor antagonists. (1989) (31)
- A pilot study of the effectiveness of d-cycloserine during cue-exposure therapy in abstinent alcohol-dependent subjects (2011) (31)
- Reduced heart rate variability in remitted bipolar disorder and recurrent depression (2016) (31)
- Imaging Endogenous Opioid Peptide Release with [11C]Carfentanil and [3H]Diprenorphine: Influence of Agonist-Induced Internalization (2014) (31)
- Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion (2017) (31)
- Brain imaging studies in human addicts (2003) (31)
- Validating the inhalation of 7.5% CO2 in healthy volunteers as a human experimental medicine: a model of generalized anxiety disorder (GAD) (2011) (31)
- Regional neurotransmitter responses after acute and chronic electroconvulsive shock (2005) (31)
- Vitamin C, Mood and Cognitive Functioning in the Elderly. (1999) (31)
- The future of non-human primate use in mAb development. (2010) (31)
- Reduced thalamic grey matter volume in opioid dependence is influenced by degree of alcohol use: a voxel-based morphometry study (2008) (30)
- Effects of the common cold on subjective alertness, reaction time and eye movements (1999) (30)
- Pharmacotherapy of anxiety. (2007) (30)
- The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description (2015) (30)
- A proof-of-concept study using [11C]flumazenil PET to demonstrate that pagoclone is a partial agonist (2005) (30)
- Alcohol Hangover: Underlying Biochemical, Inflammatory and Neurochemical Mechanisms. (2019) (30)
- Benzodiazepines in the treatment of alcoholism. (1989) (30)
- Severity of depression and response to antidepressants: GENPOD randomised controlled trial (2012) (30)
- A new approach to formulating and appraising drug policy: A multi-criterion decision analysis applied to alcohol and cannabis regulation. (2018) (30)
- Was it a vision or a waking dream? (2014) (29)
- So near yet so far: why won’t the UK prescribe medical cannabis? (2020) (29)
- Mice and rats are sensitized to the proconvulsant action of a benzodiazepine-receptor inverse agonist (FG 7142) following a single dose of lorazepam (1986) (29)
- Making a medicine out of MDMA. (2015) (29)
- Pharmacological mechanisms of benzodiazepine withdrawal. (1990) (29)
- Sleep and its disorders in translational medicine (2011) (29)
- Naltrexone ameliorates functional network abnormalities in alcohol‐dependent individuals (2017) (29)
- A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability (2017) (29)
- Substance P antagonists: novel agents in the treatment of depression (2000) (29)
- Evaluation in rat of RS-79948-197 as a potential PET ligand for central α2-adrenoceptors (1996) (28)
- Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using 11C-BU99008 PET and its relationship with amyloid load (2021) (28)
- Serotonin 5-HT 1 A receptor binding in people with panic disorder : positron emission tomography study (2008) (28)
- Impulsivity in abstinent alcohol and polydrug dependence: a multidimensional approach (2016) (28)
- In vitro and in vivo approaches to the characterization of the alpha2-adrenoceptor. (1999) (28)
- Pharmacological and behavioural studies of benzodiazepine antagonists and contragonists. (1983) (28)
- Effects of 5 weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood (2002) (28)
- Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression (2013) (28)
- First study of safety and tolerability of 3,4-methylenedioxymethamphetamine-assisted psychotherapy in patients with alcohol use disorder (2021) (28)
- Inhibition of baolofen-induced hypothermia in mice by the novel GABAB antagonist CGP 35348 (1991) (28)
- Management of insomnia: treatments and mechanisms (2007) (28)
- Sleep and daytime sleepiness the next day following single night-time dose of fluvoxamine, dothiepin and placebo in normal volunteers (2000) (28)
- Estimating drug harms: a risky business? (2009) (27)
- Drugs Without the Hot Air: Minimising the Harms of Legal and Illegal Drugs (2020) (27)
- A comparison of calcium antagonists and diazepam in reducing ethanol withdrawal tremors (2004) (27)
- GABAergic control of novelty stress-responsive epigenetic and gene expression mechanisms in the rat dentate gyrus (2011) (27)
- Impulsiveness and the prolactin response to d-fenfluramine (2000) (27)
- Establishing non-inferiority in treatment trials in psychiatry — guidelines from an Expert Consensus Meeting (2008) (27)
- Body temperature discriminates between full and partial benzodiazepine receptor agonists. (1990) (27)
- Brain function in social anxiety disorder. (2001) (27)
- 2-(4,5-dihydro-1H-imidazol-2-yl)indazole (indazim) derivatives as selective I(2) imidazoline receptor ligands. (2003) (27)
- Characterization of [3H]Harmane Binding to Rat Whole Brain Membranes (2003) (27)
- Aggressive thoughts and behavior: another symptom of panic disorder? (1989) (27)
- A Proposed Algorithm for Improved Recognition and Treatment of the Depression/Anxiety Spectrum in Primary Care. (2001) (27)
- Advancing the 3Rs in regulatory toxicology - Carcinogenicity testing: Scope for harmonisation and advancing the 3Rs in regulated sectors of the European Union. (2014) (26)
- Low Sensitivity of the Positron Emission Tomography Ligand [11C]Diprenorphine to Agonist Opiates (2007) (26)
- Rationale for, barriers to, and appropriate medication for the long-term treatment of depression. (2010) (26)
- Anxiety and OCD – the chicken or the egg? (2006) (26)
- Semantic activation in LSD: evidence from picture naming (2016) (26)
- Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives (2019) (26)
- Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence (2017) (26)
- Development and validation of the Generalized Anxiety Disorder Inventory (GADI) (2006) (26)
- History of cigarette smoking is associated with higher limbic GABAA receptor availability (2013) (26)
- Nalmefene Reduces Reward Anticipation in Alcohol Dependence: An Experimental Functional Magnetic Resonance Imaging Study (2017) (26)
- Altered Insula Connectivity under MDMA (2017) (26)
- Manifesto for a European Anxiety Disorders Research Network (2010) (26)
- Imaging Imidazoline-I2 Binding Sites in Porcine Brain Using 11C-BU99008 (2013) (25)
- First study of safety and tolerability of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in patients with alcohol use disorder: preliminary data on the first four participants (2019) (25)
- Effects of 7.5% CO2 inhalation on allocation of spatial attention to facial cues of emotional expression (2011) (25)
- Behavioral and endocrine responses to clomipramine in panic disorder patients with or without alcoholism (1995) (25)
- Anhedonia and chronic mild stress model in depression (1997) (25)
- Evidence for GABA‐A receptor dysregulation in gambling disorder: correlation with impulsivity (2016) (25)
- GENetic and clinical Predictors Of treatment response in Depression: the GenPod randomised trial protocol (2008) (25)
- Acute naltrexone does not remediate fronto‐striatal disturbances in alcoholic and alcoholic polysubstance‐dependent populations during a monetary incentive delay task (2017) (25)
- Attacks on antidepressants: signs of deep-seated stigma? (2014) (25)
- Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat (2019) (25)
- Neuropharmacological and clinical aspects of alcohol withdrawal. (1990) (24)
- Quantification of in vivo binding of [3H]RX 821002 in rat brain: evaluation as a radioligand for central alpha 2-adrenoceptors. (1992) (24)
- CLINICAL AND IMAGING STUDY: Imaging alcohol cue exposure in alcohol dependence using a PET 15O‐H2O paradigm: results from a pilot study (2006) (24)
- No psychiatry without psychopharmacology. (2011) (24)
- Effects of acute tryptophan depletion in serotonin reuptake inhibitor-remitted patients with generalized anxiety disorder (2010) (24)
- Tripping up addiction: the use of psychedelic drugs in the treatment of problematic drug and alcohol use (2017) (24)
- The relationship between benzodiazepine receptor sensitivity and neuroticism (1995) (24)
- Steps towards the international regulatory acceptance of non‐animal methodology in safety assessment (2017) (24)
- Serotonin release measured in the human brain: a PET study with [11C]CIMBI-36 and d-amphetamine challenge (2019) (24)
- Selective changes in the in vivo effects of benzodiazepine receptor ligands after chemical kindling with FG 7142 (1987) (24)
- Flumazenil challenge in social phobia (2000) (24)
- Emotional symptoms in children: The effect of maternal depression, life events, and COMT genotype (2009) (24)
- Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder (2001) (23)
- Clonidine challenge testing of alpha-2-adrenoceptor function in man: the effects of mental illness and psychotropic medication (1988) (23)
- A tale of two Es (2006) (23)
- The effect of lithium on 5-HT-mediated neuroendocrine responses and platelet 5-HT receptors (2004) (23)
- Atlas of Psychiatric Pharmacotherapy (2000) (23)
- Antidepressants in panic disorder: clinical and preclinical mechanisms. (1998) (23)
- GABA-A receptors and the response to CO2 inhalation — A translational trans-species model of anxiety? (2008) (23)
- Clonidine in alcohol withdrawal: a pilot study of differential symptom responses following i.v. clonidine. (1987) (23)
- The vaccines consistency approach project: an EPAA initiative. (2015) (23)
- Deaths from “legal highs”: a problem of definitions (2014) (23)
- Psilocybin and MDMA reduce costly punishment in the Ultimatum Game (2018) (23)
- TNFα mimics the endocrine but not the thermoregulatory responses of bacterial lipopolysaccharide (LPS): Correlation with FOS-expression in the brain (1996) (22)
- Thyrotropin-releasing hormone selectively reverses lorazepam-induced sedation but not slowing of saccadic eye movements. (1992) (22)
- A single dose of FG 7142 causes long-term increases in mouse cortical beta-adrenoceptors. (1987) (22)
- Evaluation of [O-methyl-11C]RS-15385-197 as a positron emission tomography radioligand for central α2-adrenoceptors (2000) (22)
- The clinical use of buprenorphine in opiate addiction: evidence and practice (2004) (22)
- The psychobiology of posttraumatic stress disorder. (2000) (22)
- Current controversies in medical cannabis: Recent developments in human clinical applications and potential therapeutics (2021) (22)
- Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine? (2021) (22)
- Recommendations from a global cross-company data sharing initiative on the incorporation of recovery phase animals in safety assessment studies to support first-in-human clinical trials. (2014) (22)
- The neurochemistry of anxiety: an update. (1990) (22)
- Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions—II the effects of anaesthesia and current conditions on the appearance of enhanced responses following electroconvulsive shock (1980) (22)
- 3-Methyl-methcathinone: Pharmacokinetic profile evaluation in pigs in relation to pharmacodynamics (2015) (22)
- A pilot study on the effects of treatment with acamprosate on craving for alcohol in alcohol‐dependent patients (2003) (22)
- Brain imaging studies in human addicts (2003) (22)
- Eratum: Determination of [ 11 C]PBR28 binding potential in vivo: A first human TSPO blocking study (Journal of Cerebral Blood Flow and Metabolism (2014) 34 (1256)) (2014) (21)
- Effects of benzodiazepine receptor inverse agonists on locomotor activity and exploration in mice. (1992) (21)
- Generalized anxiety disorder : symptomatology, pathogenesis and management (2002) (21)
- Regional GABA concentration and [3H]-diazepam binding in rat brain following repeated electroconvulsive shock (2005) (21)
- Venlafaxine occupation at the noradrenaline reuptake site: in-vivo determination in healthy volunteers (2001) (21)
- Influence of different cellular environments on [3H]DASB radioligand binding (2012) (21)
- Investigating benzodiazepine receptor function in vivo using an intravenous infusion of DMCM. (1984) (21)
- Treating anxiety complicated by substance misuse (2002) (21)
- Whole-genome expression analysis reveals genes associated with treatment response to escitalopram in major depression (2016) (21)
- Repeated administration of subconvulsant doses of GABA antagonist drugs (2004) (20)
- RO 15-4513 does not protect rats against the lethal effects of ethanol. (1988) (20)
- How do hallucinogens work on the brain ? (2017) (20)
- Effects of external stimulation on psychedelic state neurodynamics (2020) (20)
- Panic Disorder: Clinical Diagnosis, Management and Mechanisms (1998) (20)
- Stratified medicine in psychiatry: a worrying example or new opportunity in the treatment of anxiety? (2013) (20)
- Therapeutic Alliance and Rapport Modulate Responses to Psilocybin Assisted Therapy for Depression (2022) (20)
- Effect of single and repeated electroconvulsive shock on the hypothalamic-pituitary-adrenal axis and plasma catecholamines in rats (2004) (20)
- Evaluation of an operant successive negative contrast task as a method to study affective state in rodents (2012) (20)
- Challenge tests: assessment of the noradrenergic and GABA systems in depression and anxiety disorders. (1992) (20)
- Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review (2021) (20)
- An effective hangover treatment: Friend or foe? (2017) (19)
- The full cost and burden of disorders of the brain in Europe exposed for the first time (2011) (19)
- The effect of intravenous flumazenil on interictal electroencephalographic epileptic activity: results of a placebo-controlled study. (1991) (19)
- Agents in Development for Anxiety Disorders (2000) (19)
- Behavioral, neuroendocrine, and cardiovascular response to flumazenil: no evidence for an altered benzodiazepine receptor sensitivity in panic disorder (1999) (19)
- Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men (2015) (19)
- NICE: The National Institute of Clinical Excellence - or Eccentricity? Reflections on the Z-drugs as hypnotics (2005) (19)
- Study Protocol for “Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study” (2021) (19)
- Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice (2006) (19)
- Medical cannabis in the UK: From principle to practice (2020) (19)
- Effects of naltrexone are influenced by childhood adversity during negative emotional processing in addiction recovery (2017) (18)
- Dopamine and social anxiety disorder. (2006) (18)
- The effects of clonidine on cardiovascular responses to standing in healthy volunteers (1995) (18)
- Opiate agonists and antagonists modulate taste perception in opiate-maintained and recently detoxified subjects (2013) (18)
- Evidence for serotonin function as a neurochemical difference between fear and anxiety disorders in humans? (2015) (18)
- The effects of idazoxan on reaction times, eye movements and the mood of healthy volunteers and patients with upper respiratory tract illnesses (1999) (18)
- Alcohol antagonists--the continuing quest. (1988) (18)
- Acute and chronic idazoxan in normal volunteers: biochemical, physiological and psychological effects (1991) (18)
- NAPSAQ-1: National Patient Sleep Assessment Questionnaire in depression (2009) (17)
- The benzodiazepine antagonist, Ro 15-1788 does not decrease ethanol withdrawal convulsions in rats. (1985) (17)
- The entropic tongue: Disorganization of natural language under LSD (2020) (17)
- Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers (2003) (17)
- Validated Method for the Quantification of Baclofen in Human Plasma Using Solid-Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry. (2016) (17)
- Tryptophan depletion does not modify response to CCK-4 challenge in patients with panic disorder after treatment with citalopram (2006) (17)
- The Neurochemistry of Addiction (1997) (17)
- Understanding Depression: A Translational Approach (2009) (17)
- Buprenorphine/naloxone versus methadone and lofexidine in community stabilisation and detoxification: A randomised controlled trial of low dose short-term opiate-dependent individuals (2017) (17)
- Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls (2009) (17)
- The effects of flumazenil in neuropsychiatric disorders. (1995) (17)
- What one hand giveth the other taketh away: some unpredicted effects of enantiomers in psychopharmacology (2010) (17)
- Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand. (2000) (17)
- Foresight brain science, addiction and drugs project (2005) (17)
- Panic response to lactate administration in alcoholic and nonalcoholic patients with panic disorder. (1989) (17)
- Pharmacology should be at the centre of all preclinical and clinical studies on new psychoactive substances (recreational drugs) (2014) (17)
- Animal Models for Obsessive-Compulsive Disorder (2004) (17)
- Effects of chronic treatment with benzodiazepine receptor ligands on cortical adrenoceptors. (1986) (16)
- Idazoxan-induced reductions in cortical glucose use are accompanied by an increase in noradrenaline release: Complementary [14C]2-deoxyglucose and microdialysis studies (1995) (16)
- A Multicriteria Decision Analysis Comparing Pharmacotherapy for Chronic Neuropathic Pain, Including Cannabinoids and Cannabis-Based Medical Products (2021) (16)
- Selective Ligands for Benzodiazepine Receptors: Recent Developments (1990) (16)
- Treating Depression Effectively: Applying Clinical Guidelines (2004) (16)
- Making sense of GABAA receptor subtypes: is a new nomenclature needed? (2005) (16)
- Psilocybin for anxiety and depression in cancer care? Lessons from the past and prospects for the future (2016) (16)
- Allowing for non-adherence to treatment in a randomized controlled trial of two antidepressants (citalopram versus reboxetine): an example from the GENPOD trial (2014) (16)
- Dopamine transporter binding in females with panic disorder may vary with clinical status. (2010) (16)
- Developing a real-world evidence base for prescribed cannabis in the United Kingdom: preliminary findings from Project Twenty21 (2021) (16)
- Distribution of [(3)H]BU224, a selective imidazoline I(2) binding site ligand, in rat brain. (2002) (16)
- Biological predictors of pharmacological therapy in anxiety disorders (2015) (16)
- Neurochemical binding profiles of novel indole and benzofuran MDMA analogues (2016) (16)
- The physical health challenges in patients with severe mental illness: cardiovascular and metabolic risks (2010) (16)
- The hypothermie response to clonidine is absent in alcohol withdrawal but returns in abstinence (1988) (16)
- Studies on [3H]Diazepam and [3H]Ethyl‐β‐Carboline Carboxylate Binding to Rat Brain In Vivo. II. Effects of Electroconvulsive Shock (1983) (16)
- Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals (2018) (16)
- Benzodiazepine receptor function in anxiety disorders. (1995) (16)
- Aspects of alpha‐2‐adrenoceptor function in normal volunteers (1988) (16)
- On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain (2004) (15)
- Government vs science over drug and alcohol policy (2009) (15)
- Increased central alpha2-adrenoceptor sensitivity in panic disorder (2004) (15)
- Cannabis based medicines and cannabis dependence: A critical review of issues and evidence (2021) (15)
- Receptor-informed network control theory links LSD and psilocybin to a flattening of the brain’s control energy landscape (2022) (15)
- Assessment of GABAA benzodiazepine receptor (GBzR) sensitivity in patients on benzodiazepines (1999) (15)
- Effects of upper respiratory tract illnesses, ibuprofen and caffeine on reaction time and alertness (2014) (15)
- Changes in cardiovascular function after venlafaxine but not pregabalin in healthy volunteers: a double‐blind, placebo‐controlled study of orthostatic challenge, blood pressure and heart rate (2013) (15)
- Seizures in a night club (2007) (15)
- A comparison of the effects of phenelzine treatment with moclobemide treatment on cardiovascular reflexes (1995) (15)
- Efficacy of mirtazapine in clinically relevant subgroups of depressed patients (1998) (15)
- Moclobemide in the treatment of social phobia (1996) (15)
- Optimising PET approaches to measuring 5‐HT release in human brain (2015) (15)
- A U-shaped relationship between systolic blood pressure and panic symptoms: the HUNT study (2012) (15)
- Imidazoline2 (I2) binding site- and α2-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis (2002) (15)
- Introduction. The neurobiology of drug addiction: new vistas (2008) (15)
- Ranking the harm of non-medically used prescription opioids in the UK. (2015) (15)
- Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures (2018) (15)
- Addiction research and theory: a commentary on the Surgeon General's Report on alcohol, drugs, and health (2018) (15)
- Discontinuation of Vioxx. Authors' reply (2005) (15)
- The influence of different cellular environments on PET radioligand binding: An application to D2/3-dopamine receptor imaging (2014) (15)
- The processing of automatic thoughts of drug use and craving in opiate-dependent individuals. (2000) (15)
- Prescriptions, licences and evidence (1998) (15)
- Lamotrigine for attention deficit-hyperactivity disorder comorbid with mood disorders: a case series (2014) (14)
- Single chemical entity legal highs: assessing the risk for long term harm. (2012) (14)
- Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation? (2012) (14)
- Imipramine in panic disorder. 1. Clinical response and pharmacological changes (1991) (14)
- Characterisation of imidazoline I2 binding sites in pig brain. (2005) (14)
- γ-aminobutyric acid as a metabolite: Interpreting magnetic resonance spectroscopy experiments (2016) (14)
- The modulatory action of harmane on serotonergic neurotransmission in rat brain (2015) (14)
- Through a glass darkly: can we improve clarity about mechanism and aims of medications in drug and alcohol treatments? (2012) (14)
- Depression and generalized anxiety (1998) (14)
- Buprenorphine‐cocaine Interactions in Mice: Effect on Locomotor Activity and Hole‐dipping Behaviour (1993) (14)
- Using Ro 15-1788 to investigate the benzodiazepine receptor in vivo: Studies on the anticonvulsant and sedative effect of melatonin and the convulsant effect of the benzodiazepine Ro 05-3663 (2004) (14)
- Where now for schizophrenia research? (2014) (14)
- Neuroscience in recession? (2011) (14)
- Perverse effects of the precautionary principle: how banning mephedrone has unexpected implications for pharmaceutical discovery (2011) (14)
- The ICCAM platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part B: fMRI description (2016) (14)
- Redistribution of slow wave activity of sleep during pharmacological treatment of depression with paroxetine but not with nefazodone (2009) (14)
- Selective δ-opioid receptor ligands: potential PET ligands based on naltrindole (2001) (14)
- Oxytocin and vasopressin responses to ECT (1990) (13)
- Comprar Addiction Medicine | David Nutt | 9780199539338 | Oxford University Press (2009) (13)
- Investigations on the "set-point" theory of benzodiazepine receptor function. (1992) (13)
- Sedative antidepressants impair visual detection mechanisms in humans (1996) (13)
- Imidazoline2 (I2) Receptor- and α2- Adrenoceptor-Mediated Modulation of Hypothalamic-Pituitary-Adrenal Axis Activity in Control and Acute Restraint Stressed Rats (2004) (13)
- Exploring the pharmacology of the pro-convulsant effects of α2-adrenoceptor antagonists in mice (2005) (13)
- New directions in the treatment of anxiety disorders (2003) (13)
- Antidepressants, withdrawal, and addiction; where are we now? (2019) (13)
- Applying the 3Rs to non-human primate research: Barriers and solutions (2017) (13)
- In vitro and in vivo effect of BU99006 (5-isothiocyanato-2-benzofuranyl-2-imidazoline) on I2 binding in relation to MAO: Evidence for two distinct I2 binding sites (2007) (13)
- 5-Isothiocyanato-2-benzofuranyl-2-imidazoline (BU99006) an irreversible imidazoline2 binding site ligand: in vitro and in vivo characterisation in rat brain (2002) (13)
- Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality. (1990) (13)
- Benzodiazepine-receptor mediated convulsions in infant rats: Effects of beta-carbolines (1986) (13)
- Diazepam and Ro 15-1788 increase absence epilepsy in WAG/Rij rats chronically exposed to diazepam. (1990) (13)
- Effect of chloride or glucose on the incidence of lactate-induced panic attacks. (1995) (13)
- Drivers and barriers in the consistency approach for vaccine batch release testing: Report of an international workshop. (2017) (12)
- Acute D 3 Antagonist GSK 598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence (2017) (12)
- Early evidence on the effects of regulators' suicidality warnings on SSRI prescriptions and suicide in children and adolescents (2007) (12)
- A global initiative to refine acute inhalation studies through the use of 'evident toxicity' as an endpoint: Towards adoption of the fixed concentration procedure. (2015) (12)
- The Effects of Electroconvulsive Therapy on Plasma Insulin and Glucose in Depression (1992) (12)
- The effect of diazepam on indices of 5-HT function in man (1986) (12)
- Personalized Risk Assessment of Drug-Related Harm Is Associated with Health Outcomes (2013) (12)
- Elucidation of neurobiology of anxiety disorders in children through pharmacological challenge tests and cortisol measurements: a systematic review (2012) (12)
- Chapter 5.1 Phenomenology of anxiety disorders (2008) (12)
- A pharmacodynamic study of the α2‐adrenergic receptor antagonist ethoxyidazoxan in healthy volunteers (1994) (12)
- Resting state synchrony in anxiety-related circuits of abstinent alcohol-dependent patients (2013) (12)
- Extraction of active clonidine-displacing substance from bovine lung and comparison with clonidine-displacing substance extracted from other tissues. (1999) (12)
- N1'-fluoroethyl-naltrindole (BU97001) and N1'-fluoroethyl-(14-formylamino)-naltrindole (BU97018) potential delta-opioid receptor PET ligands. (2002) (12)
- Addiction: lifestyle choice or medical diagnosis? (2013) (12)
- A cognitive dysfunction in anxiety and its amelioration by effective treatment with SSRIs (1995) (12)
- Effect of short-term escitalopram treatment on neural activation during emotional processing (2016) (11)
- Endogenous opioids may be involved in idazoxan-induced food intake (1992) (11)
- Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions—I the effects of single and repeated bicuculline-induced seizures (1980) (11)
- Strain differences in response to a benzodiazepine receptor inverse agonist (FG 7142) in mice (2004) (11)
- Let not the best be the enemy of the good. (2011) (11)
- Inertial Demons: A Momentum-Based Diffeomorphic Registration Framework (2016) (11)
- Inverse agonists – What do they mean for psychiatry? (2017) (11)
- Future directions in substance dependence research. (2003) (11)
- RO 15-4513 and its interaction with ethanol. (1988) (11)
- Regionally specific changes in extracellular noradrenaline following chronic idazoxan as revealed by in vivo microdialysis. (1994) (11)
- Psychedelics and related drugs: therapeutic possibilities, mechanisms and regulation (2018) (11)
- Psychopharmacological characterisation of the successive negative contrast effect in rats (2015) (11)
- Mind‐altering drugs and research: from presumptive prejudice to a Neuroscientific Enlightenment? (2014) (11)
- Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic (2013) (11)
- The effects of 7.5% carbon dioxide inhalation on task performance in healthy volunteers (2012) (11)
- Hemispheric language asymmetry in first episode psychosis and schizotypy: the role of cannabis consumption and cognitive disorganization. (2015) (11)
- Comparison of the effects of benzodiazepine and beta-carboline inverse agonists on body temperature in mice. (1991) (11)
- Desipramine binding to noradrenaline reuptake sites in cardiac sympathetic neurons in man in vivo. (2000) (11)
- Anxiety disorders comorbid with depression : panic disorder and agoraphobia (2002) (11)
- Highlights of the international consensus statement on major depressive disorder. (2011) (11)
- Anxiety and Panic Disorders (1996) (11)
- The effect of a clinically effective and non‐effective dose of lorazepam on 7.5% CO2‐induced anxiety (2012) (11)
- The role of serotonin in panic: evidence from tryptophan depletion studies (2004) (11)
- Alcohol and the Brain (2021) (11)
- Why medical cannabis is still out of patients’ reach—an essay by David Nutt (2019) (10)
- Randomized, double-blind comparison of sertraline and placebo for posttraumatic stress disorder in a Department of Veterans Affairs setting (2007) (10)
- Behavioural tasks sensitive to acute abstinence and predictive of smoking cessation success: a systematic review and meta‐analysis (2016) (10)
- Cyproterone to treat aggressivity in dementia: a clinical case and systematic review (2011) (10)
- Pharmacogenetics of Psychotropic Drugs (2002) (10)
- Women with diarrhoea-predominant irritable bowel syndrome show an increased pressure response to 35% carbon dioxide stress challenge (2009) (10)
- Alpha-2-adrenoceptor control of cortisol and ACTH in normal volunteers: Preliminary open trial of the effects of acute and chronic idazoxan (1992) (10)
- Acute effects of MDMA on trust, cooperative behaviour and empathy: A double-blind, placebo-controlled experiment (2020) (10)
- Calming the Brain: Benzodiazepines and related drugs from laboratory to clinic (2003) (10)
- Accelerated communication α2-adrenoceptor antagonists block the stimulant effects of cocaine in mice (1992) (10)
- Manifesto for an international digital mental health network (2019) (10)
- Chapter 1.1 Introduction to the handbook on fear and anxiety (2008) (10)
- Acute effects of cannabis on speech illusions and psychotic-like symptoms: two studies testing the moderating effects of cannabidiol and adolescence (2020) (10)
- Benzodiazepines, plasma MHPG and alpha-2-adrenoceptor function in man. (1987) (10)
- Infecting the brain to stop addiction? (2004) (10)
- Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence (2017) (10)
- Cognition in schizophrenia: Summary Nice Consultation Meeting 2012 (2013) (10)
- Comparison of the effects of chronic desmethylimipramine administration on alpha 2- and beta-adrenoceptors in different regions of rat brain. (1983) (10)
- Consensus Statement on European Brain Research: the need to expand brain research in Europe – 2015 (2016) (10)
- Neuropharmacological Aspects of ECT: In Search of the Primary Mechanism of Action. (1989) (10)
- Is the association of hypertension and panic disorder explained by clustering of autonomic panic symptoms in hypertensive patients? (2008) (10)
- Pindolol augmentation of sertraline in resistant depression and its effect on sleep (1998) (10)
- Psychopharmacology of schizophrenia (1992) (10)
- Arthritis and serotonergic antidepressants. (2001) (10)
- Endogenous Indoleamines Demonstrate Moderate Affinity for I2 Binding Sites (1999) (10)
- Ketamine—the real perspective (2016) (9)
- Platelet alpha 2-adrenoceptor binding does not predict brain alpha 2-adrenoceptor function. (1987) (9)
- Which Metrics Should Be Used in Non-linear Registration Evaluation? (2015) (9)
- Social phobia: illness or illusion? (2001) (9)
- Treatment of cluster headache with mirtazapine. (1999) (9)
- Human Functional Neuroimaging Connectivity Research in Dependence (2005) (9)
- Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta‐regression analysis to develop an enrichment strategy (2021) (9)
- Flumazenil and saccadic eye movements in patients with panic disorder and normal controls (1992) (9)
- The effects of antidepressant drugs and 5-HT1A agonists on human sleep (2008) (9)
- Antipsychotics, HERG and sudden death (2003) (9)
- Exploring the pharmacology of the pro-convulsant effects of alpha 2-adrenoceptor antagonists in mice. (1991) (9)
- A Brief Outline of the Use of New Technologies for Treating Substance Use Disorders in the European Union (2017) (9)
- Generalized anxiety disorder : diagnosis, treatment and its relationship to other anxiety disorders (1998) (9)
- New psychoactive substances: Pharmacology influencing UK practice, policy and the law. (2020) (9)
- Alcohol and Relatively Pure Cannabis Use, but Not Schizotypy, are Associated with Cognitive Attenuations (2014) (9)
- Paroxetine reduces social anxiety in individuals with a co-occurring alcohol use disorder (2007) (9)
- Early action of nefazodone in anxiety associated with depression (1996) (9)
- Using [11C]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism (2016) (9)
- Disturbances across whole brain networks during reward anticipation in an abstinent addiction population (2020) (9)
- Long-term treatment strategies in anxiety disorders. (2002) (9)
- First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site (2018) (8)
- Repeated electroconvulsive shock does not change [3H]-paroxetine binding to the 5-HT uptake site in rat cortical membranes (2004) (8)
- Psychopharmacology of benzodiazepines—an update (1995) (8)
- Hallucinogens and dissociative drugs (2016) (8)
- Psychopharmacological Treatments: An Overview (2005) (8)
- Help luck along to find psychiatric medicines (2014) (8)
- A multi criteria decision analysis (MCDA) for evaluating and appraising government policy responses to non medical heroin use. (2021) (8)
- Assessment of GABAA benzodiazepine receptor (GBzR) sensitivity in patients with alcohol dependence. (2008) (8)
- Effects of bupropion augmentation in escitalopram-resistant patients with major depressive disorder: an open-label, naturalistic study. (2009) (8)
- Antagonist—agonist combinations as therapies for heroin addiction: back to the future? (2010) (8)
- Estimation of endogenous noradrenaline release in rat brain in vivo using [3H]RX 821002 (2005) (8)
- Venlafaxine: a new class of antidepressant. (2002) (8)
- Does blinding of readers affect the results of meta-analyses? (1997) (8)
- Towards earlier diagnosis and treatment of disorders of the brain (2018) (8)
- Naltrexone differentially modulates the neural correlates of motor impulse control in abstinent alcohol‐dependent and polysubstance‐dependent individuals (2018) (8)
- Rapid tryptophan depletion following cognitive behavioural therapy for panic disorder (2011) (8)
- Relationship between astrocyte reactivity, using novel 11C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals (2021) (8)
- Are 5-HT receptors or β-adrenoceptors involved in idazoxan-induced food and water intake? (1992) (8)
- The anxiety factor in depression (1995) (8)
- Investigation of the involvement of opioid receptors in the action of anticonvulsants (2005) (8)
- Why doctors have a moral imperative to prescribe and support medical cannabis—an essay by David Nutt (2022) (8)
- Moclobemide in the treatment of social phobia. (1996) (8)
- The neurobiology of addiction : new vistas (2010) (8)
- Influence of agonist induced internalization on [3H]Ro15‐4513 binding—an application to imaging fluctuations in endogenous GABA with positron emission tomography (2015) (8)
- Hypothermic responses to infection are inhibited by alpha2-adrenoceptor agonists with possible clinical implications. (2009) (8)
- Prescribing antidepressants post Cipriani et al (2009) (8)
- Imaging and Genetic Approaches to Inform Biomarkers for Anxiety Disorders, Obsessive-Compulsive Disorders, and PSTD. (2018) (8)
- The prescriber's guide to classic MAO-inhibitors (phenelzine, tranylcypromine, isocarboxazid) for treatment-resistant depression. (2022) (7)
- On assessing potential efficacy for vortioxetine in generalized anxiety disorder (2012) (7)
- P.2.a.044 Efficacy of trazodone in primary insomnia; a double-blind randomised placebo controlled polysomnographic study (2009) (7)
- Interaction between diazepam and noradrenergic function in man (1986) (7)
- Pharmacological treatment of panic disorder (2007) (7)
- Good sleep habits (2007) (7)
- Why I think antidepressants cause more harm than good (2014) (7)
- Strain differences in sensitivity to the hypothermic effects of benzodiazepine receptor ligands in mice (2005) (7)
- Maintenance buprenorphine for opioid users (2003) (7)
- Drugs Futures 2025 (2007) (7)
- Effects of LSD on music-evoked brain activity (2017) (7)
- Dynamic Neurotransmitter Interactions in Alcohol Withdrawal (2006) (7)
- Antidepressants; what’s the beef? (2019) (7)
- Noradrenaline in depression: half a century of progress. (1997) (7)
- The effect of clonidine on plasma MHPG: Evidence against tonic alpha2-adrenoceptor control of noradrenergic function (2004) (7)
- New victims of current drug laws (2013) (7)
- Repeated electroconvulsive shock normalizes blood glucose levels in genetically obese mice (C57BL/6J ob/ob) but not in genetically diabetic mice (C57BL/KsJ db/db) (1988) (7)
- Selective effect of lithium on cognitive performance in man (2004) (7)
- Why Less Is Always More in the Treatment of Alcohol Use Disorders. (2019) (7)
- Psychotherapies, alone and in combination (2007) (7)
- Psychedelic experience dose-dependently modulated by cannabis: results of a prospective online survey (2021) (7)
- Concerns regarding conclusions made about LSD-treatments (received 25 October 2016) (2017) (7)
- Neurobiology of Anxiety and Panic (1995) (7)
- The effect of 6-week treatment with escitalopram on CCK-4 challenge: A placebo-controlled study in CCK-4-sensitive healthy volunteers (2013) (7)
- Exploring delta-receptor function using the selective opioid antagonist naltrindole. (1989) (7)
- Lactate-induced electrolyte changes in the cerebrospinal fluid of rabbits (1990) (7)
- Differential effects of selective mu-, kappa- and delta-opioid antagonists on electroshock seizure threshold in mice. (1991) (7)
- Chapter 8 – Cognition Enhancers (2007) (7)
- The Watts Connectedness Scale: a new scale for measuring a sense of connectedness to self, others, and world (2022) (7)
- Does baseline fatigue influence treatment response to reboxetine or citalopram in depression? An open label randomized controlled trial (2012) (7)
- Harmane: An atypical neurotransmitter? (2015) (7)
- Introduction to the handbook on fear and anxiety (2008) (6)
- Building bridges between neuroscientific evidence and policy (2015) (6)
- Low affinity hypothalamic [3H]mazindol binding: a probe for hypothalamic body weight regulation? (1989) (6)
- Comparison of the effects of repeated electroconvulsive shock on alpha 2- and beta-adrenoceptors in different regions of rat brain. (1982) (6)
- Epidemiology and prevention (2016) (6)
- Differential effects of selectiveµ-,κ- andδ-opioid antagonists on electroshock seizure threshold in mice (2005) (6)
- The effects of idazoxan and other α2‐adrenoceptor antagonists on urine output in the rat (1992) (6)
- 2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic α2 receptor ligands (2006) (6)
- Preclinical screening for antidepressant activity - shifting focus away from the Forced Swim Test to the use of translational biomarkers. (2021) (6)
- Effects of the common cold on subjective alertness, simple and choice reaction time and eye movements (1999) (6)
- Progress in Mind: Focus on Alcohol Use Disorders, an Elsevier Resource Centre (2015) (6)
- Imidazoline ligand BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease (2020) (6)
- The effect of repeated electroconvulsive shock on the function of THIP, a GABA agonist (1984) (6)
- Should the supply of cannabis be legalised now? (2019) (6)
- Scopolamine: useful medicine or dangerous drug? (2014) (6)
- Compound asset sharing initiatives between pharmaceutical companies, funding bodies, and academia: Learnings and successes (2019) (6)
- Toxicological evaluation of 5‐methoxy‐2‐aminoindane (MEAI): Binge mitigating agent in development (2017) (6)
- The value of real world evidence: The case of medical cannabis (2022) (6)
- Effect of Single and Repeated Electroconvulsive Shock on Body Temperature in Mice. (1989) (6)
- Pharmacology and pathophysiology (2016) (6)
- Cannabis and opioid overdoses: time to move on and examine potential mechanisms. (2018) (6)
- The effects of the α2-adrenoceptor antagonist idazoxan on sleep in normal volunteers (1991) (6)
- The Basics of Project Evaluation and Lessons Learned (2018) (6)
- Decreased brain modularity after psilocybin therapy for depression. (2021) (6)
- Neurochemical Aspects of Anxiety (2007) (6)
- Antidepressant effects of a psychedelic experience in a large prospective naturalistic sample (2022) (6)
- Tryptophan Research in Panic Disorder (2008) (6)
- Endocrine response to syncope in panic disorder (1989) (6)
- Imidazoline(2) (I(2)) binding site- and alpha(2)-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis. (2002) (6)
- Antidepressants and mania: To stop or not to stop? (1993) (6)
- Benzodiazepine receptor sensitivity in panic disorder (1991) (6)
- Neural correlates of the DMT experience as assessed via multivariate EEG (2019) (6)
- Correction to: The hidden therapist: evidence for a central role of music in psychedelic therapy (2018) (5)
- Cerebro-spinal fluid studies in alcoholics and violent offenders (1988) (5)
- Flumazenil as an anti-epileptic agent (1991) (5)
- SAT-6-5 The role of SSRIs in anxiety disorders (1995) (5)
- Brain mechanisms of social anxiety disorder. Discussion (1998) (5)
- Evidence-based guidelines for pharmacological treatment of anxiety disorders (2013) (5)
- An evaluation of the fixed concentration procedure for assessment of acute inhalation toxicity (2018) (5)
- A call to reprioritise metrics to evaluate illicit drug policy (2016) (5)
- Psychedelics therapeutics: What we know, what we think, and what we need to research (2022) (5)
- Altered trajectories in the dynamical repertoire of functional network states under psilocybin (2018) (5)
- Biological Markers of Generalized Anxiety Disorder. (2018) (5)
- Treating Depression Effectively: Second Edition (2007) (5)
- Antagonizing the behavioral effects of ethanol using drugs that act at the benzodiazepine/GABA receptor macromolecular complex (1988) (5)
- Brain dynamics predictive of response to psilocybin for treatment-resistant depression (2022) (5)
- A comparison of the effects of sertraline and clomipramine on postural blood pressure changes and heart rate and blood pressure variability (1994) (5)
- Electroconvulsive Shock Does Not Increase Plasma Insulin in Rats. (1988) (5)
- Generalized Anxiety Disorder Inventory (2018) (5)
- Practical Pharmacotherapy for Anxiety (1997) (5)
- L-4 Focusing on serotonin for the action of drugs effective in mood disorders: pre-synaptic versus postsynaptic mechanisms (1996) (5)
- Does electroconvulsive shock therapy work through opioid mechanisms? (1990) (5)
- Effects of chronic alpha 2-adrenoceptor blockade on platelet and lymphocyte adrenoceptor binding in normal volunteers. (1991) (5)
- Imipramine in panic disorder. 2. Effects on α2-adrenoceptor function (1991) (5)
- Pharmacology and Treatments (2007) (5)
- Alpha-2-adrenoceptor function in alcoholics. (1988) (5)
- Isolation of RP-HPLC pure clonidine-displacing substance from NG108-15 cells. (2000) (5)
- Evaluation in rat of RS-79948-197 as a potential PET ligand for central alpha 2-adrenoceptors. (1996) (5)
- Organization of Opioid Receptors in Human Brain and Drug Interactions Studied by PET and SPECT Imaging: Implications for Treatment Strategies for Opiate Addiction (1997) (5)
- Restrictions on drugs with medical value: Moving beyond stalemate (2018) (5)
- Evaluation of 11 C-BU99008, a Positron Emission Tomography ligand for the Imidazoline 2 binding sites in Rhesus brain (2013) (5)
- Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms (2017) (5)
- Can Neuroscience Improve Addiction Treatment and Policies? (2013) (5)
- Effect of benzodiazepine and beta-carboline antagonists and partial agonists on loprazolam- and ZK 93423-induced hypothermia. (1991) (5)
- The treatment of insomnia. (2004) (5)
- Psychiatric and physical comorbidities in depression (2007) (5)
- Science and non-science in UK drug policy. (2010) (5)
- Discontinuation of Vioxx (2005) (5)
- Effect of the cyclopyrrolones suriclone and RP 59037 on body temperature in mice. (1992) (5)
- Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence (2017) (5)
- 3-(Methoxycarbonyl)-amino-beta-carboline reduces both the sedative and anticonvulsant effects of diazepam. (1989) (5)
- Cannabis antagonists: a new era of social psychopharmacology? (2005) (5)
- Pharmacological characterisation of novel α2-adrenoceptor antagonists as potential brain imaging agents (2004) (5)
- Pharmacological Treatment of Nocturnal Sleep Disturbances (2010) (4)
- Recommended diagnosis and management of insomnia (2014) (4)
- Effects of classic psychedelic drugs on turbulent signatures in brain dynamics (2022) (4)
- Platelet monamine receptor binding in alcoholics during withdrawal. (1987) (4)
- Use of selective serotonin reuptake inhibitors and other serotonergic drugs in the biological dissection of affective disorders (1995) (4)
- A randomised trial of the effect of the glycine reuptake inhibitor Org 25935 on cognitive performance in healthy male volunteers (2014) (4)
- Comparison of Crude Methanolic CDS Extracts from Various Tissues (1999) (4)
- Psychiatric disorders and cardiovascular disease: anxiety, depression and hypertension (2008) (4)
- Characteristics of People Seeking Prescribed Cannabinoids for the Treatment of Chronic Pain: Evidence From Project Twenty 21 (2022) (4)
- Debunking the myth of ‘Blue Mondays’: No evidence of affect drop after taking clinical MDMA (2021) (4)
- The Unhappy Saga of `Happy Pills' (2003) (4)
- Cognitive processing in post-traumatic stress disorder. (1996) (4)
- BRAIN SEROTONIN RELEASE IS REDUCED IN PATIENTS WITH DEPRESSION: A [11C]Cimbi-36 PET STUDY WITH A D-AMPHETAMINE CHALLENGE. (2022) (4)
- Treatment of Sleep Disorders in Adults (1999) (4)
- Cannabinoids and the endocannabinoid system in fibromyalgia: A review of preclinical and clinical research. (2022) (4)
- Synthesis of 2,3,5,6-tetrahydro-3H-imidazo[2,1-b] [1,3,5]benzotriazepines and their oxidative ring contraction into 1-(4,5-dihydro-1H-imidazol-2-yl)-1H-benzimidazoles. (2005) (4)
- Comprar Treating Depression Effectively: Applying Clinical Guidelines, Second Edition | Michael E. Thase | 9780415439107 | Informa Healthcare (2007) (4)
- The extinction of drugs for clinical research: Can the ECNP medicines chest save them? (2014) (4)
- Psychotherapy meets neuroscience (2005) (4)
- Neurobiological mechanisms in generalized anxiety disorder. Discussion (2001) (4)
- Repeated electroconvulsive shock does not increase the susceptibility of rats to a cage convulsant (Isopropylbicyclophosphate) (1980) (4)
- P.1.g.013 Effects of vortioxetine versus paroxetine on polysomnography in man: a pharmacokinetic/pharmacodynamic study (2013) (4)
- Psychedelics – Re-opening the doors of perception (2018) (4)
- Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals. (2021) (4)
- Antidepressant drugs and the cardiovascular system: a comparison of tricyclics and SSRIs and their relevance for the treatment of psychiatric patients with cardiovascular problems (1997) (4)
- Conditioned anticipatory anxiety in normal volunteers (1996) (4)
- Informed consent - a new approach to drug regulation? (2006) (4)
- The Rise of Three Rs Centres and Platforms in Europe* (2022) (4)
- Cannabis and cannabis resin pre-review report. A document prepared for the World Health Organization Expert Committee on Drug Dependence, Thirty-eight meeting Geneva, 14 – 18 November 2016. (2016) (4)
- Effects of 7.5% CO2-Induced Anxiety on Individual Performance During a Group Computer Combat Game (2013) (4)
- Hypophysectomy alters both 5-hydroxytryptamine- and alpha 2-adrenoceptor-mediated behavioural changes in the rat. (1983) (4)
- Pharmacological treatment of bipolar disorder (2007) (4)
- Centralα-2 adrenoceptors are responsible for a clonidine-induced cue in a rat drug discrimination paradigm (2005) (4)
- Open letter from UK based academic scientists to the secretaries of state for digital, culture, media and sport and for health and social care regarding the need for independent funding for the prevention and treatment of gambling harms (2020) (4)
- Behavioural pharmacology (2020) (4)
- Low serotonergic tone and elevated risk for substance misuse (2011) (4)
- Visualizing classification of drugs used in psychotic disorders: A ‘subway map’ representing mechanisms, established classes and informal categories (2022) (3)
- A depressed man requesting St John's wort. (1999) (3)
- A technique for chronic catheterization of the cisterna magna in rabbits. (1988) (3)
- Rationale for the development of the Z–drugs (2008) (3)
- The effect of 1-(4,5-dihydro-1H-imidazol-2-yl) isoquinoline on monoamine release and turnover in the rat frontal cortex (2007) (3)
- Hypophysectomy does not prevent the enhanced monoamine-mediated behavioural responses following repeated electroconvulsive shocks (1982) (3)
- Tapering of SSRI treatment to mitigate withdrawal symptoms. (2019) (3)
- Management of panic disorder in primary care (2017) (3)
- Chapter 20 – Psychotropic drugs (2012) (3)
- Insomnia: guide to diagnosis and choice of treatment (2008) (3)
- P-5-19 Antidepressant-like effects of the I2 ligands idazoxan and 2-BFI in the rat porsolt test (1996) (3)
- Legal highs: a problem of definitions? – Authors' reply (2014) (3)
- Attenuation of the behavioural effects of ethanol in mice by des-enkephalin-gamma-endorphin (ORG 5878). (1992) (3)
- Anticonvulsant activity of the imidazoline 6,7-benzoidazoxan (1991) (3)
- THuNDRous news for human dopamine researchers: A selective dopamine D1 receptor antagonist will soon be available for clinical research (2018) (3)
- Life Care Planning and Case Management Handbook (2004) (3)
- Reply to letter by Green, Marsden and Fone (2007) about Sessa and Nutt's editorial (MDMA: baby with the bath water) in the November 2007 Journal (2008) (3)
- Individual and combined effects of cannabidiol and Δ9-tetrahydrocannabinol on striato-cortical connectivity in the human brain (2022) (3)
- Increased low-frequency brain responses to music after psilocybin therapy for depression (2022) (3)
- Guidelines for the management of social phobia/social anxiety disorder (1999) (3)
- Individual and combined effects of Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) on striato-cortical connectivity in the human brain (2020) (3)
- Panic attacks are more likely to include autonomic symptoms in patients with hypertension than in normotensives — a comparison of symptoms, and factor analysis (2006) (3)
- Lithium treatment effect on serotonin function. (1990) (3)
- Benzodiazepine-serotonin interactions in man. (1987) (3)
- Neurochemistry of drugs other than alcohol (1993) (3)
- Neuroreceptor science: a clarification of terms. (1988) (3)
- The European College of Neuropsychopharmacology (ECNP) Medicines Chest Initiative: Rationale and Promise (2015) (3)
- Pharmacological cognitive enhancement in healthy people: Potential and concerns (2013) (3)
- Acute acetate administration increases endogenous opioid levels in the human brain: A [11C]carfentanil molecular imaging study (2021) (3)
- Behavioral tasks sensitive to acute abstinence and predictive of smoking cessation success: a systematic review and meta-analysis. (2016) (3)
- Pharmacokinetics for psychiatrists (2004) (3)
- Canalization and plasticity in psychopathology (2022) (3)
- Thyrotropin-releasing hormone: A potential comparator for the panicogenic effects of pentagastrin and CCK? (1996) (3)
- Peptide receptors as targets for anxiolytic drugs (2000) (3)
- CHAPTER 52 – The Analysis of Brain PET Radioligand Displacement Studies (1996) (3)
- Some important changes (2004) (3)
- Tis a wonder it works at all (1997) (3)
- SSRIs and Sleep in Man (2006) (3)
- Alcohol consumption during pregnancy and children's cognitive development: Mendelian randomization study using the ADH1B genotype (2010) (3)
- Neurochemical insights into alcohol kindling (1989) (3)
- Pharmacological and psychological aspects of drugs abuse (2012) (3)
- STATE OF THE EVIDENCE CANNABIS USE AND REGULATION (2015) (3)
- RELATIONSHIP BETWEEN ASTROCYTE ACTIVATION USING [11C]BU99008 PET, GLUCOSE METABOLISM AND AMYLOID IN ALZHEIMER’S DISEASE: A DEMENTIA PLATFORM UK EXPERIMENTAL MEDICINE STUDY (2018) (3)
- Medical cannabis and epilepsy in the UK – A qualitative analysis of the carers’ perspective: “We're asking for quality of life for our children” (2021) (3)
- Management of insomnia: treatments and mechanismsi. (2007) (3)
- Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice (2004) (3)
- Synthesis and in vivo evaluation of [11C]BU99008 as a ligand for the imidazoline I2 binding site (2010) (3)
- Default Mode Network Modulation by Psychedelics: A Systematic Review (2022) (3)
- Considerations on the role of buprenorphine in recovery from heroin addiction from a UK perspective (2015) (3)
- Drugs Futures 2025? Perspective of the Pharmaceutical Industry (2007) (3)
- Massive overuse or appropriate medical intervention? The modern-day use of antidepressants. (2012) (3)
- Brain Imaging in Addiction (2012) (3)
- Licit drug use and depression, anxiety and stress (2006) (3)
- Benzodiazepines and the other sedative-hypnotics (2016) (3)
- Not only but also? Comments on "How does convulsive therapy work"? (1990) (2)
- P-11-33 The analysis of brain pet radioligand displacement studies (1995) (2)
- Paroxetine and its uses in psychiatry. (1999) (2)
- P.2.a.034 The risk of suicide and suicidal ideation in depressed patients with sleep disturbance (2009) (2)
- Rob Kerwin — an appreciation (2007) (2)
- British Association for Psychopharmacology Consensus on the Treatment of Bipolar Disorder (2003) (2)
- Basic mechanisms of benzodiazepine tolerance, dependence, and withdrawal (1990) (2)
- Mood and Anxiety Disorders in Children and Adolescents : A Psychopharmacological Approach (2001) (2)
- Structural and functional neuroimaging of the effects of opioids (2002) (2)
- P.1.007 Assessment of cellular environments on radioligand binding – an application to opioid receptor PET imaging (2011) (2)
- Behavioral Facilitation (2006) (2)
- Subjective and objective assessment of the effects of noise, noise sensitivity and noise disturbed sleep on health (2001) (2)
- Same difference? Evidence versus ‘common sense’ in the Coalition Drug Strategy (2011) (2)
- Some Contributions on How to Formulate Drug Policies and Provide Evidence-Based Regulation (2021) (2)
- A pilot study of the effect of short-term escitalopram treatment on brain metabolites and gamma-oscillations in healthy subjects (2016) (2)
- Correction: DMT alters cortical travelling waves (2020) (2)
- The Neurobiology of Addiction (2010) (2)
- P.3.008 Endogenous opioid release in pathological gamblers after an oral amphetamine challenge: a [C]carfentanil PET study (2014) (2)
- Changes in caffeine seizure threshold after electroconvulsive shock (2004) (2)
- Human brain effects of DMT assessed via EEG-fMRI (2023) (2)
- Chronic alcohol exposure differentially modulates structural and functional properties of amygdala: A cross‐sectional study (2020) (2)
- Autoradiography of I2 Receptors in Frog Brain (1999) (2)
- Running head : Genomic subtypes of CFS / ME Seven genomic subtypes of Chronic Fatigue Syndrome / Myalgic Encephalomyelitis ( CFS / ME ) : a detailed analysis of gene networks and clinical phenotypes (2007) (2)
- Introduction to the 2016 Consensus Document on European Brain Research (2016) (2)
- in patients with cardiovascular disease Treatment of anxiety and depressive disorders (2004) (2)
- P-2-85 Sleep in depressed outpatients during treatment with fluvoxamine — a home-based study (1995) (2)
- Diagnosing sleep disorders (2013) (2)
- Generalized social phobia and avoidant personality disorder: meaningful distinction or useless duplication? (2007) (2)
- The uptake of a fluorescently labelled antisense oligonucleotide in vitro and in vivo (2005) (2)
- Sex differences in depressive symptoms and tolerability after treatment with selective serotonin reuptake inhibitor antidepressants: Secondary analyses of the GENPOD trial (2020) (2)
- The effect of acute and chronic electroconvulsive shock on [3H]phorbol-dibutyrate binding to rat brain membranes (1988) (2)
- Maintenance pharmacotherapy of unipolar depression (1999) (2)
- Nutt damage – Author's reply (2010) (2)
- Insomnia: guide to diagnosis and recommended management (2011) (2)
- The hidden therapist: evidence for a central role of music in psychedelic therapy (2018) (2)
- Drugs and harm to society reply (2011) (2)
- Chronic alcohol exposure differentially modulates structural and functional properties of amygdala: A cross‐sectional study (2020) (2)
- Principled sentencing for drug supply offences: Revised methamphetamine sentencing guidelines in New Zealand (2020) (2)
- Brain PET radioligand displacement studies: modelling 11-C flumazenil displacement by i.v. midazolam in man (1995) (2)
- Psychiatric co-morbidity (2016) (2)
- Synthesis and in vivo evaluation of (11)C BU99008 as a ligand for the imidazoline I(2) binding site (2011) (2)
- Current status of anxiolytic drugs (2001) (2)
- How can we use current knowledge to improve antidepressant treatments (2009) (2)
- Depression and generalised anxiety disorder: Separation evidence (1999) (2)
- Gene-Tailored Treatments for Brain Disorders: Challenges and Opportunities (2016) (2)
- Generalized Anxiety Disorder (1998) (2)
- Medical cannabis for severe treatment resistant epilepsy in children: a case-series of 10 patients (2021) (2)
- Chapter 1 Normal sleep (2008) (2)
- Selective delta-opioid receptor ligands: potential PET ligands based on naltrindole. (2001) (2)
- CLINICAL CORRELATES OF BENZODIAZEPINE RECEPTOR FUNCTION (1992) (2)
- Letters (1991) (2)
- P.l.c.044 Paradoxical effects of GABA on the in vivo uptake of the partial inverse GABA agonist [3H]Ro15-4513 in rat brain (2009) (2)
- Solution-Focused Brief Practice with Long-Term Clients in Mental Health Services. "I am More than my Label." (2008) (2)
- Conclusion and overview (2018) (2)
- The role and basis of the drug laws (2010) (2)
- Analogue controls : An imperfect law (2012) (2)
- Cardiac slowing and acute tryptophan depletion: a comment on the paper by van der Veen et al. (2009) (1)
- S.28.05 Antidepressant mechanisms in anxiety disorders (2003) (1)
- PHARMACOLOGY AND CELL METABOLISM Assessment of GABAA Benzodiazepine Receptor (GBzR) Sensitivity in Patients with Alcohol Dependence (2008) (1)
- PHARMACOENDOCRINE STUDIES IN ANXIETY (1992) (1)
- Key elements for a new governance of addictive substances and behaviours (2017) (1)
- magnetic resonance imaging study with psilocybin Implications for psychedelic-assisted psychotherapy : functional (2017) (1)
- Cognitive style, alprazolam plasma levels, and treatment response in panic disorder (2007) (1)
- P.6.f.002 Endogenous opioid release in pathological gamblers after an oral amphetamine challenge: a [11C]carfentanil PET study (2014) (1)
- Prescribing antidepressants post (2009) (1)
- Body mass index (BMI) does not predict responses to psilocybin (2022) (1)
- Changes in music-evoked emotion and ventral striatal functional connectivity after psilocybin therapy for depression (2022) (1)
- Does opioid induced dopamine release in humans require a subjective "high"? A pet study with 11C-raclopride (2002) (1)
- Noradrenaline – the forgotten amine? (2013) (1)
- Sleep Research and Affective Disorders (2005) (1)
- 19th biennial IPEG Meeting (2016) (1)
- S.08.05 PET imaging of benzodiazepine receptors and their relationship to anxiety disorders (1996) (1)
- Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review – CORRIGENDUM (2022) (1)
- P.3.05 Current and former ecstasy users report different sleep to matched controls: a web based questionnaire study (2008) (1)
- The ICCAM platform study (2017) (1)
- Do Opioid, alpha(2)-Adrenoreceptors, or Benzodiazepine Receptors Mediate ECS-Induced Hypothermia in Mice? (1991) (1)
- Chapter 10 Other drugs (2009) (1)
- C-11-diprenorphine PET imaging of opioid binding during chronic methadone treatment and early abstinence (2000) (1)
- Effects of psilocybin versus escitalopram on rumination and thought suppression in depression (2022) (1)
- Apolipoprotein E genotyping in Alzheimer's disease. The UK Alzheimer's Disease Genetic consortium. (1996) (1)
- The imaging science of PET (1999) (1)
- The Aggregates Levy (2018) (1)
- Astrogliosis in aging and Parkinson’s disease dementia: a new clinical study with 11C-BU99008 PET (2022) (1)
- Addiction (Oxford Psychiatry Library) (2018) (1)
- C.16.02 Generalized anxiety disorder: A comorbid disease (2004) (1)
- EVALUATION OF NOVEL ASTROCYTE MARKER [11C]BU99008 PET IN ALZHEIMER’S DISEASE: A DEMENTIA PLATFORM U.K. EXPERIMENTAL MEDICINE STUDY (2018) (1)
- Focus on Depression and Anxiety Disorders in General Medicine (2001) (1)
- Hypnotics and anxiolytics. (1983) (1)
- Long-term effects of SSRIs and TCAs on sleep (1994) (1)
- Consensus Statement on the Benefit to the Community of ESEMeD Survey Data on Depression and Anxiety (2007) (1)
- P.1.i.042 A multicenter positron emission tomography study of GABA receptor availability in adults with autism (2017) (1)
- Effects of fluvoxamine and clomipramine treatment on beat-by-beat changes in blood pressure during standing (1993) (1)
- Are baseline physical symptoms characteristic of severe depression or a poor prognostic factor? Secondary analysis of the GenPod trial (2013) (1)
- Mescaline: The forgotten psychedelic (2022) (1)
- “Groundhog decade not brave new world” (2020) (1)
- UNDERSTANDING CAUSAL PATHWAYS: A RESPONSE TO THE COMMENTARIES (2008) (1)
- The pharmaceutical industry and psychiatric research - a marriage for richer...? (2005) (1)
- Sodium oxybate for the maintenance of abstinence in alcohol-dependent patients: An international, multicenter, randomized, double-blind, placebo-controlled trial (2022) (1)
- The effects of idazoxan and other alpha 2-adrenoceptor antagonists on urine output in the rat. (1992) (1)
- VENLAFAXINE AND PREGABALIN REDUCE CO2-INDUCED SYMPTOMS OF ANXIETY IN AN EXPERIMENTAL HUMAN MODEL (2011) (1)
- Key concepts in psychopharmacology (2004) (1)
- A Bayesian Reanalysis of a Trial of Psilocybin Versus Escitalopram for Depression (2022) (1)
- More than just smoke: Psychopharmacology of cannabinoids (2021) (1)
- S-16-5 SSRIS, TCAS and augmentation therapies — Exploring mechanisms by acute and chronic sleep effects (1996) (1)
- A new vision for the Journal of Psychopharmacology (2002) (1)
- Gene-by-Environment (Serotonin Transporter and Childhood Maltreatment) Interaction for Anxiety Sensitivity, an Intermediate Phenotype for Anxiety Disorders (2007) (1)
- Psilocybin for Depression. Reply. (2021) (1)
- Evolution of antidepressant agents (2007) (1)
- Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: Reduction by a selective serotonin reuptake inhibitor (2007) (1)
- Asking the other experts: UK users’ views on the ‘rational scale’ of harms associated with psychoactive substances. (2010) (1)
- CHAPTER 5 – The MOC Counter: A Pharmacological Tool for the in Vivo Measurement of Ligand Occupancy Indices in the Human Brain (1996) (1)
- S.21.03 Can CO2 be used to model different anxiety disorders? (2004) (1)
- GABAAbenzodiazepine receptor (GBzR) sensitivity: test–retest reliability in normal volunteers (2000) (1)
- Coping with irregular working hours: preventing sleep problems in doctors, nurses, and other health professionals (2013) (1)
- Chapter 40 - Anxiolytics (2012) (1)
- What is addiction? (2018) (1)
- Z drugs: their properties and use in treating insomnia (2013) (1)
- The development and validation of a human screening model of tobacco abstinence. (2019) (1)
- Flawed assumption in analysis (2011) (1)
- Question-based Drug Development for psilocybin - Authors' reply. (2016) (1)
- Beat to beat monitoring of orthostatic hypotension — a comparison of phenelzine with moclobemide (1993) (1)
- David Nutt: Champions off-licence prescribing (2015) (1)
- Author’s reply: ‘Suppressing addiction using high-dose baclofen, rather than using substitution therapy’ (2012) (1)
- Brain circuits involved in craving (2000) (1)
- Drugs and harm to society – Authors' reply (2011) (1)
- Psychedelics and related drugs: therapeutic possibilities, mechanisms and regulation (2018) (1)
- Chapter 66 – Opioids Neuroimaging (2013) (1)
- Drugs Affecting Sexual Function (2006) (1)
- Are multiple physical symptoms a poor prognostic factor or just a marker of depression severity? Secondary analysis of the GenPod trial (2014) (1)
- Putting the MD back into MDMA (2021) (1)
- Specific treatmentS and diSorderS Antidepressants (2007) (1)
- A dangerous attitude to drugs (2009) (1)
- Author response: DMT alters cortical travelling waves (2020) (1)
- UK drugs strategy promises to be tough on criminals, but evidence shows this doesn't work (2021) (1)
- Is the UK’s 2017 drug strategy fit for purpose? (2017) (1)
- New ACMD regulations threaten UK's pharmaceutical discovery (2017) (1)
- P-2-90 Antidepressant actions on peripheral visual detection mechanisms in humans (1995) (1)
- An investigation of effects of fluvoxamine and dothiepin on sleep and daytime sleepiness in normal volunteers (1994) (1)
- Repeated administration of subconvulsant doses of GABA antagonist drugs (2004) (1)
- Functional evaluation of NK1 antagonism on cue reactivity in opiate dependence; An fMRI study (2021) (1)
- British Association for Psychopharmacology (BAP) (1990) (1)
- The approach to new anxiolytics. (1993) (1)
- Private sector impact on the harm done by addictive substances (2017) (1)
- A critical review of studies measuring endogenous 5-HT release by emission tomography (2010) (1)
- OPL Sleep Disorders (2013) (1)
- Neuroimaging as a Biomarker for the Diagnosis, Progression, and Treatment of Substance Abuse Disorders (2012) (1)
- Dr Shipman’s last legacy: e-surveillance of the medical profession (2005) (1)
- Chapter 3 Approaches to management (2009) (1)
- Retracted. Effects of 7.5% CO2 inhalation on allocation of spatial attention to facial cues of emotional expression. (2008) (1)
- P.6.c.008 Respiratory changes following benzodiazepine administration in opioid-dependent human participants (2010) (0)
- P.6.a.008 A pilot study of the effectiveness of D-cycloserine during cue-exposure therapy in abstinent alcohol dependent subjects (2009) (0)
- Chapter 5.4 Principles and findings from human imaging of anxiety disorders (2008) (0)
- Sensitivity in Panic Disorder (2015) (0)
- Blood flow changes during deep brain stimulation for treatment resistant depression: A PET study (2010) (0)
- Noradrenergic dysfunction in generalised anxiety disorder (GAD: a SPET study using a clonidine challenge (2002) (0)
- The effects of zolpidem on in vivo binding of [C11]-flumazenil and [C11]-Ro15-4513 (2010) (0)
- Electronic Version Single-User License Agreement (2012) (0)
- The Landfill Tax (2012) (0)
- and cortisol measurements : a systematic review Elucidation of neurobiology of anxiety disorders in children through pharmacological challenge tests (2012) (0)
- Cambridge Textbook of Effective Treatments in Psychiatry: A critical assessment of methods and processes used to develop psychiatric drug treatments (2008) (0)
- P-79AN FMRI STUDY OF NALMEFENE ON ALCOHOL EFFECTS IN REWARD ANTICIPATION IN ALCOHOL DEPENDENCE (2015) (0)
- availability receptor 3 / D 2 History of cannabis use is not associated with alterations in striatal dopamine D (2011) (0)
- Editorial Venlaxine: the yin and yang of antidepressants (1995) (0)
- Reply to OCD letter (2008) (0)
- Bupropion improved symptoms in adults with attention deficit hyperactivity disorder (2001) (0)
- Substance misuse and young people: Reward mechanisms (2019) (0)
- Books Received (2008) (0)
- Pharmacological Treatments for Anxiety Disorders: how do they work? (2007) (0)
- Correction to: Imaging and Genetic Approaches to Inform Biomarkers for Anxiety Disorders, Obsessive-Compulsive Disorders, and PSTD. (2018) (0)
- Efficacy and Safety of Extended-Release Venlafaxine in the Treatment of Generalized Anxiety Disorder in Children and Adolescents: Two Placebo-Controlled Trials (2007) (0)
- Building Prices per Functional Unit (2012) (0)
- Pharmacodynamics of addictive substances (2018) (0)
- Melatonin (Circadin): a novel hypnotic for use in older patients (2008) (0)
- Part 7 - Useful Addresses for Further Information (2012) (0)
- Practical issues in using antidepressants (2007) (0)
- S.04.07 Role of monoamine oxidase in imidazoline2 binding site mediated function in rat brain (2003) (0)
- The Tryptophan Depletion Technique in Psychiatric Research (2001) (0)
- Neurotransmitter Systems and Their Clinical Disorders Edited by N. J. Legg. Published by Academic Press, 1978. $19.50. ISBN 0-12-443050-3 (1981) (0)
- Decreased α 2 -adrenoceptor numbers in rat brain following repeated electro-convulsive shock (1981) (0)
- Speaker: Toshikazu Saito, Japan (2016) (0)
- The NEW Journal of Psychopharmacology (1991) (0)
- Drugs used in the treatment of the addictions (2012) (0)
- Miscellaneous Drugs/Treatment Modalities (2006) (0)
- Antidepressant Drugs and Mood Stabilizers (2006) (0)
- P-11-32 The multiple objects coincidences counter (MOCC) — a new tool for the measurement of ligand tissue occupancy in vivo in man (1995) (0)
- GAD and obsessive–compulsive disorder (1998) (0)
- Synthesis and Biological Activities of Novel 1,2,3,5‐Tetrahydroimidazo[2,1‐b]quinazoline Derivatives. (2005) (0)
- P.1.e.029 Investigating the effect of expectation on striatal dopamine release in heroin addicts: an 11C-raclopride PET study (2011) (0)
- S.18.04 Does heroin release dopamine? A positron emission tomography study (2005) (0)
- Chapter 8 Sleep disorders associated with neurological and medical disorders (2008) (0)
- Chapter 7 Psychiatric disorders and sleep (2008) (0)
- Empowering young people to manage drug-related risk (2017) (0)
- Substance use and specific healthcare settings (2016) (0)
- Chapter 4 Alcohol (2009) (0)
- Psychoactive drugs of misuse: rationalising the irrational (2007) (0)
- Establishing the diagnosis (2016) (0)
- Speaker: David Nutt, UK (2016) (0)
- Other addictive disorders (2016) (0)
- Impulsivity in abstinent alcohol and polydrug dependence: a multidimensional approach (2016) (0)
- The Current Status of Psychedelics in Australian Medicine (2021) (0)
- Chapter 2 Diagnosing sleep disorders (2008) (0)
- Chapter 1 The scope of addiction medicine (2009) (0)
- Imaging the role of dopamine in human opioid addicts (2010) (0)
- Stressors and the adjustment disorders. Edited by J. D. Noshpitz and R. D. Coddington. Wiley, New York, 1990. No. of pages: 693 (1991) (0)
- Assessing drug-related harm – Authors' reply (2007) (0)
- P.6.b.007 Clinical relevance of nalmefene in the treatment of alcohol dependence: subgroup analysis of patients with high drinking risk level (2013) (0)
- N Furniture/Equipment (2012) (0)
- Further validation of the quinpirole-induced compulsive checking paradigm as a model for obsessive-compulsive disorder (OCD)-restraint stress exacerbates some compulsive checking measures (2005) (0)
- Adrenoceptor numbers increase after kindling with the benzodiazepine receptor ligand FG 7142 (1985) (0)
- Mental Health – the hidden epidemic (2020) (0)
- S-3-3 The comparative effects of SSRIs and TCAs on sleep architecture (1995) (0)
- Alcohol misuse and anxiety : prevalence and incidence (2002) (0)
- Prevalence, burden and diagnosis (2007) (0)
- Cannabis, frontal lobe functioning and schizotypy-What is the nature of the association?: (512592013-354) (2011) (0)
- S.11.02 Validation of CO2 stress test in humans (2007) (0)
- P.331 The relationship between reward processing and impulsivity in addiction: a functional magnetic resonance imaging study (2020) (0)
- Drug pharmacokinetics and abuse liability (2018) (0)
- S-27-2 Imidazoline receptors: CNS pharmacology and clinical relevance (1996) (0)
- The ideal treatment of withdrawal (2002) (0)
- Evidence based antidepressant selection across depressive disorders (2007) (0)
- The story of modern tranquilliser drugs (2020) (0)
- Neuropsychopharmacology across brain diseases (2012) (0)
- Reply from the Editors (2007) (0)
- S-47-3 Receptor mechanisms of benzodiazepine dependence (1996) (0)
- Mapping neural activation to alcohol cues in abstinent alcoholics — variability of behavioural and rCBF responses in the scanner environment (2001) (0)
- Do Gut Hormones attenuate eating and addictive behaviours in obesity, alcohol and nicotine dependence? (2018) (0)
- P.021 Comparison of food cue reactivity, eating behaviours, mood and impulsivity in obesity, ex-smokers and abstinent alcohol dependence (2020) (0)
- Effect of anaesthetic administration on the appearance of enhanced monoamine-mediated behaviours following electroconvulsive shock (1980) (0)
- Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study (2014) (0)
- Speaker 3: Hiroyuki Uchida, Japan (2016) (0)
- An appreciation of Richard Lister (1991) (0)
- P.8.a.030 Validation of a translational model of insomnia in rats and human volunteers (2006) (0)
- Neurochemical studies in normal volunteers (1988) (0)
- P.3.017 Human impulsivity is not associated with variation in presynaptic striatal dopamine synthesis capacity (2012) (0)
- Structures of benzodiazepine recognition site ligands (2020) (0)
- The dopamine system and addiction (2018) (0)
- 7.5% CO 2 : a model of GAD? (2002) (0)
- C.04.01 Treatments for generalised anxiety disorder: mechanism of action and clinical effect (2010) (0)
- phenotypes analysis of gene networks and clinical syndrome / myalgic encephalomyelitis : a detailed Seven genomic subtypes of chronic fatigue (2008) (0)
- Insomnia as a predictor of depression in UK primary care (2009) (0)
- Corrigendum to The Australian Drug Harms Ranking Study (2019) (0)
- Value Added Tax (2012) (0)
- Chapter 9 Psychostimulants (2009) (0)
- CNS volume 14 issue 4 Cover and Back matter (2009) (0)
- Functional connectivity analysis of rCBF in opiate craving (2002) (0)
- Chapter 5 Tobacco (2009) (0)
- Legal and ethical issues (2016) (0)
- Brain dopamine response in human opioid addiction R. C. Daglish, Tim M. Williams, Sue J. Wilson, Lindsay G. Taylor, Chin B. Eap, (2008) (0)
- Specific treatmentS and diSorderS Anxiolytics (2007) (0)
- Brain imaging alcohol cue-reactivity (2004) (0)
- Alcohol and drug abuse (2000) (0)
- New concepts of addiction (2017) (0)
- Using sleep to measure relative 5HT uptake blockade (2002) (0)
- S Piped Supply Systems (2012) (0)
- Editorial: Practical pharmacotherapy for anxiety disorders (1997) (0)
- Contents of the American Journal of Psychiatry (1995) (0)
- Management of panic disorder in the primary‐care setting (2009) (0)
- Alpha 2-adrenoceptor antagonists block the stimulant effects of cocaine in mice. (1992) (0)
- Chapter 9 Pharmacology of sleep (2008) (0)
- Approaches to reducing the harm done by addictive substances and behaviours should be comprehensive and address the whole population (2017) (0)
- Drugs for the Treatment of Symptoms Related to Substance Abuse (2006) (0)
- Annual Event: Utopia or Dystopia? Living in hope not fear (2011) (0)
- alcohol treatments? Through a glass darkly: can we improve clarity about mechanism and aims of medications in drug and (2012) (0)
- Speaker 1: David Nutt, UK (2016) (0)
- A single photon emission tomography (SPET) study of noradrenergic function in generalised anxiety disorder (GAD) (2002) (0)
- Appetite hormones and addiction (2018) (0)
- Measuring the serotonin uptake site using [3H]paroxetine--a new serotonin uptake inhibitor. (1988) (0)
- Increased global integration in the brain after psilocybin therapy for depression (2022) (0)
- Benzodiazepine terminology. (1988) (0)
- Effects of upper respiratory tract illnesses, ibuprofen and caffeine on reaction time and alertness (2013) (0)
- P.2.a.035 Persistence with hypnotics in depressed patients treated in UK primary care (2009) (0)
- Chapter 6 Sedative hypnotics (2009) (0)
- Basilar artery blood flow velocity changes in patients with panic disorder following 35% carbon dioxide challenge (2007) (0)
- P.2.a.033 Initiation of hypnotics or anxiolytics in depressed patients treated in UK primary care (2009) (0)
- A risky business? Comparing the harms of alcohol and other recreational drugs (2021) (0)
- Demons: Our Changing Attitudes to Alcohol, Tobacco, and Drugs, Virginia Berridge. Oxford University Press (2013), Pp 304. £16·99., ISBN: 9780199604982 (2014) (0)
- Chapter 11 Psychiatric co-morbidity (2009) (0)
- P.2.a.032 Resource use in depressed patients with sleep disturbance (2009) (0)
- S34.05 New approaches to imidazoline receptors (2000) (0)
- Windows/Doors/Stairs (2012) (0)
- Anxiety: clinical considerations for behavioural pharmacologists (1997) (0)
- Effects of repeated electro-convulsive shock on β-adrenergic receptors in rat brain (1981) (0)
- E.01.02 Clinical aspects of GABA (2009) (0)
- Functional Alternatives to Alcohol (2022) (0)
- Pharmacogenetic Aspects of Anxiolytic drugs: Focus on GABA-Benzodiazepine Receptor Complex (2002) (0)
- Remove barriers to clinical research for schedule 1 drugs with therapeutic potential (2023) (0)
- Reply to commentaries (2006) (0)
- The scope of intervention (2016) (0)
- P.6.b.005 An fMRI study of nalmefene on alcohol effects in reward anticipation in alcohol dependence (2015) (0)
- CRITICAL CARE Hypothermic responses to infection are inhibited by a 2 -adrenoceptor agonists with possible clinical implications (2009) (0)
- Chapter 5 Parasomnias (2008) (0)
- A PET study testing the dopamine hypothesis in opiate dependence in humans (2002) (0)
- Psychiatric disorders and sleep (2013) (0)
- P.4.a.005 Rapid onset anxiolitic efficacy after a single dose of pregabalin: evaluation using dental anxiety model (2007) (0)
- Mental Capital and Wellbeing: Making the most of ourselves in the 21st century State-of-Science Review: SR-E13 Neurocognition and Social Cognition in Middle-Aged and Older Adult Drug Users: Vulnerability and Consequences (2008) (0)
- Cardiovascular reflexes during treatment of social phobia with moclobemide (2001) (0)
- Ego-Dissolution Inventory (2017) (0)
- The GABA system and addiction (2018) (0)
- Dopamine receptor genotypes in non-dependent and dependent smokers (2004) (0)
- Functional Neuroimaging of the Acute Effects of Drugs of Abuse (2011) (0)
- Comparison of food cue reactivity and eating behaviours in obesity, ex-smokers and abstinent alcohol dependence. (2021) (0)
- E.06.01 Setting the stage – Antidepressants (2011) (0)
- Identification and treatment of individuals with attention-deficit/hyperactivity disorder and substance use disorder: An expert consensus statement (2023) (0)
- Number of Tables : 2 Number of Figures : 4 Supplemental Information : 0 (2014) (0)
- Treatment Strategies (Evidence-Based) (2006) (0)
- P.2.a.048 NAtional Patient Sleep Assessment Questionnaire III (Napsaq-lll) in depression; a survey for psychiatrists (2009) (0)
- Lebedev HBM 2016-Supplement (2016) (0)
- Injecting drug use (2016) (0)
- Preparation, structure and affinity for imidazoline I2 receptors and alpha2-adrenoceptors of 1-[(4,5-dihydroimidazolidin-2-yl)imino]indan-2-ols. (2005) (0)
- Chapter 14 Difficult and urgent situations (2009) (0)
- Structural characterisation of the GABAA receptor (2020) (0)
- Chapter 3 Insomnia (2008) (0)
- Psychopharmacological imaging. (1995) (0)
- Pharmacogenetics of anxiolytic drugs and the GABA–benzodiazepine receptor complex (2002) (0)
- PM298. Dissociable effects of cannabinoids on anticipatory and consummatory reward processing (2016) (0)
- Sleep and cortisol profiles in healthy volunteers using an automated blood sampling machine (2008) (0)
- P.4.c.005 The cardiovascular effects of a subtype selective and non-selective benzodiazepine agonist in healthy volunteers (2009) (0)
- The nature of addictive disorders (2016) (0)
- From CRH to cognitions: BAP Symposium on the Neurobiology of Stress (1990) (0)
- The opioid system and addiction (2018) (0)
- Regional cerebral increases in opioid receptor density in early abstinence from methadone: a PET study in man (2003) (0)
- History of cigarette smoking associated with increased limbic GABA(A) receptor availability (2012) (0)
- Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence (2022) (0)
- Acute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis ‘amotivational’ hypotheses (2016) (0)
- S.10.05 Imaging brain opioid receptors in alcohol and heroin dependence (2005) (0)
- Does the locus coeruleus mediate the effects of the CO2 challeng (2002) (0)
- Pain and opioids (2016) (0)
- SATISFIED WITH DISSATISFACTION? AUTHORS' REPLY (1999) (0)
- Consulting Engineers' Fees (2012) (0)
- Chapter 10 Coping with irregular working hours: preventing sleep problems in junior doctors, nurses, and other health professionals (2008) (0)
- Benzodiazepines as anxiolytics (2020) (0)
- RCPsych Regional meeting Bristol (2004) (0)
- Civil society approaches to reducing the harm done by addictive substances (2017) (0)
- S.07.07 Increased opioid receptor binding in early abstinence from dependent opioid and alcohol use and relationship to craving (2007) (0)
- Comparison of food cue reactivity and eating behaviours in obesity, ex-smokers and abstinent alcohol dependence (2020) (0)
- Are treatments combining pharmacotherapy and cognitive-behavioural therapy for anxiety disorders more efficient than either treatment alone? (2007) (0)
- Sodium Oxybate for Alcohol Dependence: A Network Meta-Regression Analysis Considering Population Severity at Baseline and Treatment Duration (2023) (0)
- Neurobiology of PTSD (2001) (0)
- Editorial: Psychopharmacology of the prefrontal cortex (1997) (0)
- C.08.01 The role of neuroimaging in anxiety disorders (2011) (0)
- Q Paving/Planting/Fencing/Site Furniture (2012) (0)
- S.1.02 Antidepressant pharmacotherapy – 2009 and beyond (2009) (0)
- A double-blind comparison of acute buprenorphine with placebo in schizophrenia (1992) (0)
- Functional characterisation of the GABAA receptors (2020) (0)
- study . activity : results of a placebo-controlled interictal electroencephalographic epileptic The effect of intravenous flumazenil on (0)
- Depression in late life (2007) (0)
- Exploring antidepressant mechanisms by acute and chronic sleep effects (2002) (0)
- A Brief History of Psychopharmacology (2020) (0)
- A PET study of brain opioid receptor changes after withdrawal from chronic methadone treatment (2002) (0)
- C.20.03 Evolving therapy for managing depression: a brief look into the future (2006) (0)
- Benzodiazepine drugs in sleep disorders (2020) (0)
- Complementary, light, sleep deprivation and exercise therapies (2007) (0)
- Drugs of AbuseJohn Q. WangHumana Press. ISBN: 1‐588‐29057‐3, 2003, 505 pp. with index, $135.00 (2003) (0)
- Dr. George and Associates Reply (1990) (0)
- Methadone-bruprenorphine transfer in British opiate addicts (1996) (0)
- Typical Thermal Conductivity of Building Materials (2012) (0)
- Ego-Inflation Inventory (2017) (0)
- Circadian rhythm sleep disorders (2013) (0)
- GABA-B receptor function in healthy volunteers, a pharmacokinetic and pharmacodynamic study of two doses of baclofen compared to placebo (2015) (0)
- The psychobiology of posttraumatic stress disorder. Discussion (2000) (0)
- Pharmacokinetic determinants of clinical activity (2020) (0)
- P.2.a.021 Insomnia as a predictor of depression in UK primary care (2009) (0)
- 7.5% CO2 responses in patients with generalised anxiety disorder (2011) (0)
- Human Screening Model of Tobacco Abstinence (2019) (0)
- 149. Effects of α 2-adrenoceptor agonists and antagonists on saccades (1998) (0)
- P.8.a.030 Morning cortisol response in patients with parasomnias and insomnia (2008) (0)
- Theoretical Review ROLE OF GABA IN ANXIETY AND DEPRESSION (2007) (0)
- 2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic alpha2 receptor ligands. (2006) (0)
- Electrical Supply/Power/Lighting Systems (2012) (0)
- Alcohol anxiety and phobias (1988) (0)
- C.11.01 Can neurobiology guide the choice of treatment? (2008) (0)
- Iconographies supplémentaires de l'article : BRAIN FUNCTION IN SOCIAL ANXIETY DISORDER (2011) (0)
- In Situ Concrete/Large Precast Concrete (2012) (0)
- PM 299 Cortical thickness of resting state networks in the brain of male patients with alcohol dependence (2017) (0)
- Measuring GABA A sensitivity in patients on chronic benzodiazepines (1998) (0)
- P.3.11 Increased opioid receptor binding in early abstinence from dependent opioid and alcohol use and relationship to craving (2007) (0)
- Causation and mechanisms of GAD (1998) (0)
- Selective δ‐Opioid Receptor Ligands: Potential PET Ligands Based on Naltrindole. (2001) (0)
- Smaller fleas ad infinitum: pharmacological subtypes of anxiety? (1991) (0)
- Speaker 2: Pierre Blier, Canada (2016) (0)
- Imaging Studies in Anxiety Disorders (1996) (0)
- Reply from the Editor (2007) (0)
- Synthesis of 2,3,5,6-Tetrahydro-3H-imidazo[2,1-b][1,3,5]benzotriazepines and Their Oxidative Ring Contraction into 1-(4,5-Dihydro-1H-imidazol-2-yl)-1H-benzimidazoles. (2005) (0)
- What do drug users think about drugs (2017) (0)
- Acute nutritional state and Body Mass Index influence Anterior Cingulate Cortex activation during motor response inhibition (2018) (0)
- Best Practices and Benchmarking (2018) (0)
- Pharmacological Interventions That Have the Potential to Alter Neurotransmitter Levels in the Human Brain (2014) (0)
- Guest Editorial: Ten Years of Progress In Understanding Insomnia, 1988 To 1998 (1999) (0)
- Comprar Sleep Disorders | David Nutt | 9780199234332 | Oxford University Press (2008) (0)
- Psychotropic drug development—social, scientific and economic issues BAP Autumn Meeting, November 1993 (1994) (0)
- Road Haulage Workers employed in the Building Industry (2012) (0)
- Blood flow changes in abstinent addicts during cue exposure and craving for their drug of choice (2002) (0)
- The ethical basis for preventing harm from heavy use of addictive products (2017) (0)
- The burden of post-traumatic stress disorder (2000) (0)
- Theeffects ofidazoxan andother a2-adrenoceptor antagonists on foodandwaterintake intherat (1991) (0)
- Depression in women (2007) (0)
- Chapter 13 Specific clinical situations (2009) (0)
- Interaction of the benzodiazepines with the GABAA receptor (2020) (0)
- The glutamate system and addiction (2018) (0)
- Basic Principles of Psychiatric Pharmacotherapy (2006) (0)
- Reply to: No Clear Evidence of Reduced Brain Serotonin Release Capacity in Patients With Depression (2023) (0)
- E.05.02 Assessing the noradrenalin system in humans (2006) (0)
- P38. The Relationship Between Reward and Impulsivity in Substance Dependence: An fMRI Study (2022) (0)
- Pharmacotherapy for Anxiety—Authors' Reply (1998) (0)
- P.4.024 Using positron emission tomography to investigate microglial activation in alcohol dependence: preliminary findings (2013) (0)
- Thirty years of Journal of Psychopharmacology (2016) (0)
- P.4.a.018 Quadratic relation of frequent panic attacks with systolic blood pressure – the HUNT study (2009) (0)
- Authors and editors (1982) (0)
- P.3.014 An investigation of the role of the brain GABA-benzodiazepine receptor alpha-5 subtype in autism spectrum disorder (ASD) using the PET ligand [11C]Ro15-4513 (2012) (0)
- Modelling anxiety disorders in human volunteers (2006) (0)
- The psychedelic compound psilocybin may ‘reset’ the brain to help manage treatment-resistant major depression (2019) (0)
- Benzodiazepines: Anticonvulsant and other clinical uses (2020) (0)
- Nicotine addiction (2018) (0)
- Addiction : the clinical interface. Commentary (2008) (0)
- 588 The effects of caffeine and clonidine on eye movements (1998) (0)
- [11C](+)RX-821024: A novel tracer for imaging α2-adrenoceptors (2008) (0)
- Psychopharmacology: An Introduction (3rd edn). By René Spiegel. Chichester: John Wiley. 1996. 295 pp. £45 (hb). ISBN: 0 471 95729 1 (1997) (0)
- Ongoing management of substance use disorders (2016) (0)
- Repeated electroconvulsive shock increases the number of [3H]desipramine binding sites in rat cerebral cortex (2004) (0)
- Chapter 4 Hypersomnia (2008) (0)
- C.01.01 Debate – cognitive dysfunction in depression: reality or mirage? (2014) (0)
- Key elements of addiction (2018) (0)
- P.8.a.032 Effects on sleep of caffeine and its combination with trazodone or zolpidem in healthy volunteers (2006) (0)
- A PET study of opioid receptors in abstinent alcohol dependent patients (2004) (0)
- Sequential pharmacotherapies and treatment-resistant depression (2007) (0)
- Effect of fluvoxamine and non-selective antidepressants on cardiovascular reflexes (1992) (0)
- Building Costs Indices, Tender Prices Indices and Location Factors (2012) (0)
- Burden of addiction (2018) (0)
- European winter conference on brain research Vars-les-Claux, France March 11–16, 1985 Proceedings from workshop on ‘Benzodiazepines, 5-HT & anxiety’ (1986) (0)
- Drug-induced alterations of the post-ictal seizure threshold increase (1981) (0)
- Alterations in white matter microstructure in alcohol and alcohol‐polydrug dependence: Associations with lifetime alcohol and nicotine exposure (2022) (0)
- Psilocybin and MDMA reduce costly punishment in the Ultimatum Game (2018) (0)
- Noradrenergic function in generalised anxiety disorder (GAD): A single photon emission tomography (SPET) study (2008) (0)
- Sleep disorders associated with neurological and medical disorders (2013) (0)
- Pharmacology of sleep (2013) (0)
- Multi-user use of the Spon Press Software and eBook (2012) (0)
- Altered brain opioid receptor density after withdrawal from methadone treatment (2002) (0)
- S.21.02 How to rescue CNS active drugs which fail in one indication: experience from the ECNP Medicines Chest Initiative (2015) (0)
- A tale of two moralities: Politicians, doctors, use of addictive substances and lobbying (2018) (0)
- Addiction: biological aspects - in 100 words (2014) (0)
- A human pet study of dopamine response to hydromorphone (2002) (0)
- Generalised anxiety disorder: Remission status in patients treated with paroxetine (2002) (0)
- CARDIOVASCULAR DISEASE ANXIETY , DEPRESSION AND HYPERTENSION (2008) (0)
- P.8.a.031 Sleep stages and automatic overnight cortisol sampling (2008) (0)
- GAD and panic disorder (1998) (0)
- Bridging the preclinical - clinical gap (2005) (0)
- Are cognitive deficits associated with tobacco abstinence mediated by dopamine depletion (2017) (0)
- P Building Fabric Sundries (2012) (0)
- P.2.c.031 A national patient sleep assessment questionnaire in depression (NAPSAQ II); a survey for general practitioners (2008) (0)
- S-74-3 Quantitating benzodiazepine and opiate receptor sensitivity in addicts (1996) (0)
- Black bile and noradrenaline: alternative views on the pathogenesis of depression (1992) (0)
- P.6.c.007 Association between opioid receptor availability and anxiety in healthy controls but not in substance dependence (2009) (0)
- Genetic Factors Underlying Treatment Resistance in Psychiatry (2018) (0)
- Drivers of the harm done by drugs (2017) (0)
- S.15.03 Imaging GABA-benzodiazepine receptor subtypes in addiction (2012) (0)
- Chapter 12 Special populations (2009) (0)
- New Directions in Anxiety: OCD Spectrum Disorders (2000) (0)
- Chapter 8 Opioids (2009) (0)
- Quantity Surveyors' Fees (2012) (0)
- Persistence with hypnotics in depressed patients treated in UK primary care (2009) (0)
- Intoxicating addiction: aspects of the psychopharmacology of alcoholism. Meeting Report, Annual Congress of Medicine, Helsinki January 1990 (1990) (0)
- Chapter 7 Cannabis (2009) (0)
- Neuromodulation and other physical treatments (2007) (0)
- Buprenorphine and methadone were equally effective in reducing opiate or cocaine use (1998) (0)
- Chapter 15. Imaging (2010) (0)
- K Linings/Sheathing/Dry Partitioning (2012) (0)
- Anxiety Disorders: Current Needs and Future Prospects (2007) (0)
- The concept of generalized anxiety disorder. Historical introduction (1998) (0)
- An unsquared circle: Biological Council Symposium on Experimental Approaches to Anxiety and Depression (1991) (0)
- P.2.004 A novel rodent model of affective state-induced memory bias for psychiatry research and CNS drug safety (2012) (0)
- Are cognitive deficits associated with tobacco abstinence mediated by nicotine withdrawal (2016) (0)
- Cerebral blood flow predicts differential neurotransmitter activity (2018) (0)
- Introduction: Update on Posttraumatic Stress Disorder (2004) (0)
- Lessons Learned Scenarios in Real Life (2018) (0)
- Specific clinical situations (2016) (0)
- Initiation of hypnotics or anxiolytics in depressed patients treated in UK primary care (2009) (0)
- Anxiety Disorders Comorbid with Depression: Pocketbook: Panic Disorder and Agoraphobia (2002) (0)
- P.2.a.015 Sleep disturbance in depression: results from a UK survey (2007) (0)
- S.23.01 Recent insights into the psychopharmacology of MDMA (2016) (0)
- GABA(A) Receptors in Autism - a Multicenter Positron Emission Tomography Study (2015) (0)
- Policies and measures that impact on the harm done by addictive substances (2017) (0)
- Nutt regulation ? Popular intoxicants : what lessons can be learned from the last 40 years of alcohol and cannabis (2011) (0)
- Demolition/Alteration/Renovation (2012) (0)
- Practical Pharmacotherapy for Anxiety Disorders (1997) (0)
- Doing it by numbers (2014) (0)
- FUNCTIONAL CHANGES IN NEURONAL NICOTINIC RECEPTORS IN ALZHEIMER??S DISEASE (1996) (0)
- [New directions in GABAergic pharmacology of anxiety and depression]. (2004) (0)
- Patient access. How to wipe out a growing killer. (2011) (0)
- Attitudes to anxiety (1989) (0)
- Conclusions (2020) (0)
- The Corporate Body (2006) (0)
- Drug science, policy and law – relaunch (2021) (0)
- Author's reply (1999) (0)
- Letter to editors (1988) (0)
- Response from Neurolink (2002) (0)
- Relate Promotion Tool (2019) (0)
- How Current Drug Laws Impede Research and Clinical Treatments (2013) (0)
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- M Surface Finishes (2012) (0)
- NS.01.04 The addiction perspective in NbN (2016) (0)
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- 854. New vistas in challenge paradigms in anxiety disorders (2010) (0)
- Kerbs, Paving, etc. (2012) (0)
- Government leadership for whole-of-society approaches (2017) (0)
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- Applications of Radiotracer Imaging Poster Abstracts (2012) (0)
- DEMENTIA PLATFORM U.K. EXPERIMENTAL MEDICINE: HUMAN IN VIVO ASTROGLIAL ACTIVATION IN EARLY ALZHEIMER’S DISEASE (2017) (0)
- Imaging in neuropsychopharmacology (2001) (0)
- A single electroconvulsive shock substantially lowers blood glucose levels in obese mice (C57BL/6J ob/ob) (2004) (0)
- Medication sparing after medical cannabis initiation: A case study of a chronic pain patient in Project Twenty21 (2023) (0)
- A critical evaluation of QIDS-SR-16 using data from a trial of psilocybin therapy versus escitalopram treatment for depression. (2023) (0)
- Neurobiological processes in addiction (2018) (0)
- Corrigendum (2020) (0)
- Chapter 15 Legal and ethical issues (2009) (0)
- Chapter 2 Assessment and diagnosis: general principles (2009) (0)
- Raising awareness: The implementation of medical cannabis and psychedelics used as an adjunct to standard therapy in the treatment of advanced metastatic breast cancer (2022) (0)
- Spatial correspondence of LSD-induced variations of brain functioning at rest with serotonin receptor expression. (2023) (0)
- Alterations in white matter microstructure in alcohol and alcohol‐polydrug dependence: Associations with lifetime alcohol and nicotine exposure (2022) (0)
- The MOC counter: a new tool for the in vivo measurement of ligand occupancy ratios in the human brain (1995) (0)
- The Current Status and Work of Three Rs Centres and Platforms in Europe* (2022) (0)
- Author and Subject Index (2002) (0)
- The Babylonian and the Hebrew Genesis / by Heinrich Zimmern ; translated by J. Hutchinson (2020) (0)
- Correction to: The hidden therapist: evidence for a central role of music in psychedelic therapy (2018) (0)
- Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals (2014) (0)
- Alcohol alternatives – a goal for psychopharmacology? (2006) (0)
- Neurochemical binding profiles of novel indole and benzofuran MDMA analogues (2016) (0)
- Generalized Anxiety Disorder: Pocketbook: Diagnosis, Treatment and its Relationship to Other Anxiety Disorders (2002) (0)
- CONSENSUS DOCUMENT ON EUROPEAN BRAIN RESEARCH Chapter I : Brain development , plasticity and ageing in health and disease Section (2011) (0)
- The European College of Neuropsychopharmacology (ECNP) Medicines Chest Initiative: Rationale and Promise (2015) (0)
- Building Cost Models (2012) (0)
- Translational models of anxiety disorders for drug discovery and development (2007) (0)
- Promises and pitfalls. Commentary on Antelman et al., ???Time-dependent sensitization (TDS) ??? possible implications for clinical psychopharmacology??? (1997) (0)
- Plumbing and Mechanical Engineering Services Industry (2012) (0)
- GABA A benzodiazepine receptor sensitivity in patients with alcohol dependence (2008) (0)
- treatmentsmechanisms, a diagnostic test and specific Syndrome / Myalgic Encephalomyelitis (CFS/ME): Current research priorities in Chronic Fatigue (2006) (0)
- Chapter 6 Circadian rhythm sleep disorders (2008) (0)
- P.4.b.012 Acute anxiolytic drug treatment has no effect on the instrumental successive negative contrast effect using a modified forced choice serial reaction time task (2010) (0)
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