David P. Fairlie
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Engineering Computer Science
David P. Fairlie's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)David P. Fairlie's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Future of Peptide‐based Drugs (2013) (1348)
- MR1 presents microbial vitamin B metabolites to MAIT cells (2012) (1051)
- Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction. (1999) (708)
- Protease inhibitors: current status and future prospects. (2000) (694)
- T-cell activation by transitory neo-antigens derived from distinct microbial pathways (2014) (610)
- Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42. (2008) (548)
- Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is? (1998) (475)
- Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells (2013) (463)
- Aqueous Dissolution of Alzheimer’s Disease Aβ Amyloid Deposits by Biometal Depletion* (1999) (459)
- Histone deacetylases as regulators of inflammation and immunity. (2011) (436)
- Function, structure and therapeutic potential of complement C5a receptors (2007) (374)
- Proteases universally recognize beta strands in their active sites. (2005) (361)
- Structure, function and pathophysiology of protease activated receptors. (2011) (322)
- Activity of Recombinant Dengue 2 Virus NS3 Protease in the Presence of a Truncated NS2B Co-factor, Small Peptide Substrates, and Inhibitors* (2001) (277)
- Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers (2015) (275)
- Inflammatory lipid mediators in adipocyte function and obesity (2010) (268)
- Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells. (2000) (268)
- Constraining cyclic peptides to mimic protein structure motifs. (2014) (262)
- Protease inhibitors in the clinic. (2005) (255)
- Recognition of vitamin B metabolites by mucosal-associated invariant T cells (2013) (252)
- A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage (2016) (249)
- Low-molecular-weight peptidic and cyclic antagonists of the receptor for the complement factor C5a. (1999) (248)
- Single turn peptide alpha helices with exceptional stability in water. (2005) (237)
- A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells (2014) (216)
- Orally Absorbed Cyclic Peptides. (2017) (209)
- A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats. (2003) (208)
- Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation (2016) (202)
- New insights into growth hormone action. (2006) (199)
- Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles (2019) (195)
- Histone deacetylase inhibitors in inflammatory disease. (2009) (195)
- Amyloid peptides and proteins in review. (2007) (191)
- Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death (2007) (186)
- Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll‐like receptor 4 agonist LPS (2010) (186)
- Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals (2016) (183)
- Beta-strand mimetics. (2004) (176)
- Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure. (2005) (169)
- Human blood MAIT cell subsets defined using MR1 tetramers (2018) (166)
- Towards protein surface mimetics. (1998) (163)
- Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition. (2016) (157)
- Biased signalling and proteinase‐activated receptors (PARs): targeting inflammatory disease (2014) (156)
- A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding. (2007) (156)
- Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency (2010) (150)
- Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells (2017) (150)
- MAIT cells protect against pulmonary Legionella longbeachae infection (2018) (149)
- Complement c5a receptor facilitates cancer metastasis by altering T-cell responses in the metastatic niche. (2014) (145)
- Update 1 of: Proteases universally recognize beta strands in their active sites. (2010) (143)
- Macrocyclic Peptidomimetics Forcing Peptides into Bioactive Conformations (1995) (137)
- Solution structure of methionine-oxidized amyloid beta-peptide (1-40). Does oxidation affect conformational switching? (1998) (133)
- Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation. (2009) (132)
- Potencies of Human Immunodeficiency Virus Protease Inhibitors In Vitro against Plasmodium falciparum and In Vivo against Murine Malaria (2006) (131)
- Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat. (2002) (127)
- Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate (1999) (127)
- Antifibrotic activity of an inhibitor of histone deacetylases in DOCA‐salt hypertensive rats (2010) (125)
- Comparative α-helicity of cyclic pentapeptides in water. (2014) (124)
- Targeting HIV-1 protease: a test of drug-design methodologies. (1995) (124)
- A Potent Human C5a Receptor Antagonist Protects against Disease Pathology in a Rat Model of Inflammatory Bowel Disease 1 (2003) (122)
- C5aR and C3aR antagonists each inhibit diet‐induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling (2013) (119)
- Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity (2002) (118)
- Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing. (2000) (118)
- Homogeneous Catalysis - Conversion of 4-Pentenals to Cyclopentanones by Efficient Rhodium-Catalyzed Hydroacylation (1988) (117)
- The intracellular pathway for the presentation of vitamin B–related antigens by the antigen-presenting molecule MR1 (2016) (117)
- Protective effect of a new C5a receptor antagonist against ischemia-reperfusion injury in the rat small intestine. (2002) (116)
- Proteolysis of human hemoglobin by schistosome cathepsin D. (2001) (116)
- Flavones are inhibitors of HIV-1 proteinase. (1992) (115)
- Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc (2020) (115)
- A New Small Molecule C5a Receptor Antagonist Inhibits the Reverse-Passive Arthus Reaction and Endotoxic Shock in Rats1 (2000) (113)
- Enzymatic Characterization and Homology Model of a Catalytically Active Recombinant West Nile Virus NS3 Protease* (2004) (113)
- Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites (2015) (112)
- Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients (2014) (109)
- Improving on nature: making a cyclic heptapeptide orally bioavailable. (2014) (109)
- Potent Antimalarial Activity of Histone Deacetylase Inhibitor Analogues (2008) (108)
- Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents. (2000) (107)
- Update 1 of: Beta-strand mimetics. (2010) (106)
- Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells* (2015) (106)
- Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Relationships between structures and activity. (2004) (105)
- Catalyst-free N-arylation using unactivated fluorobenzenes. (2012) (99)
- Lysine acetylation in obesity, diabetes and metabolic disease (2012) (97)
- Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells (2017) (95)
- An antagonist of human protease activated receptor‐2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen‐induced arthritis in rats (2012) (94)
- Pharmacological characterization of antagonists of the C5a receptor (1999) (93)
- Novel agonists and antagonists for human protease activated receptor 2. (2010) (92)
- Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity (1999) (92)
- crystal Structure and Electrospray Ionization Mass Spectrometry, Electron Paramagnetic Resonance, and Magnetic Susceptibility Study of [Cu2(ascidH2)(1,2-.mu.-CO3)(H2O)2].cntdot.2H2O, the Bis(copper(II)) Complex of Ascidiacyclamide (ascidH4), a Cyclic Peptide Isolated from the Ascidian Lissoclinum pa (1994) (91)
- Antagonism of Protease-Activated Receptor 2 Protects against Experimental Colitis (2012) (90)
- Diet‐induced obesity, adipose inflammation, and metabolic dysfunction correlating with PAR2 expression are attenuated by PAR2 antagonism (2013) (89)
- Protective effects of a potent C5a receptor antagonist on experimental acute limb ischemia-reperfusion in rats. (2004) (89)
- Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases (2016) (88)
- Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. (2004) (88)
- Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor. (1999) (88)
- In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses. (2009) (87)
- A 195Pt and 15N N.M.R. study of the anticancer drug, cis-diammine-dichloroplatinum(II), and its hydrolysis and oligomerization products (1981) (85)
- Homogeneous catalysis. Mechanism of catalytic hydroacylation: the conversion of 4-pentenals to cyclopentanones (1988) (83)
- Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. (2003) (82)
- X-ray absorption spectroscopy of cadmium phytochelatin and model systems. (1999) (81)
- Comparative anti‐inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury (2004) (80)
- Targeting histone deacetylase inhibitors for anti-malarial therapy. (2009) (80)
- Histone Deacetylase 7 Promotes Toll-like Receptor 4-dependent Proinflammatory Gene Expression in Macrophages* (2013) (80)
- Small molecular probes for G-protein-coupled C5a receptors: conformationally constrained antagonists derived from the C terminus of the human plasma protein C5a. (1998) (79)
- D‐Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity (2003) (78)
- West Nile Virus NS2B/NS3 protease as an antiviral target. (2008) (78)
- Antimalarial Activity of the Anticancer Histone Deacetylase Inhibitor SB939 (2012) (76)
- MAIT cells promote tumor initiation, growth and metastases via tumor MR1. (2019) (75)
- Insights to Substrate Binding and Processing by West Nile Virus NS3 Protease through Combined Modeling, Protease Mutagenesis, and Kinetic Studies* (2006) (75)
- Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites (2015) (74)
- Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity. (2008) (74)
- Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth (2016) (72)
- Alpha-turn mimetics: short peptide alpha-helices composed of cyclic metallopentapeptide modules. (2004) (70)
- Current status of short synthetic peptides as vaccines. (2006) (70)
- A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1 (2019) (70)
- Tumor cell‐specific cytotoxicity by targeting cell cycle checkpoints (2003) (69)
- Update 1 of: Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure. (2010) (69)
- Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5a (2013) (69)
- HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation (2012) (69)
- Stapling peptides using cysteine crosslinking (2016) (69)
- Effects of a new C5a receptor antagonist on C5a‐ and endotoxin‐ induced neutropenia in the rat (1999) (69)
- Nonpeptidic ligands for peptide-activated G protein-coupled receptors. (2007) (68)
- Toward drugs for protease-activated receptor 2 (PAR2). (2013) (68)
- Inhibition of C5a-induced neutrophil chemotaxis and macrophage cytokine production in vitro by a new C5a receptor antagonist. (2000) (67)
- Recipient mucosal-associated invariant T cells control GVHD within the colon (2018) (67)
- Agonists and antagonists of protease activated receptors (PARs). (2006) (67)
- Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma (2018) (67)
- Is Oxidative Damage by β-Amyloid and Prion Peptides Mediated by Hydrogen Atom Transfer from Glycine α-Carbon to Methionine Sulfur within β-Sheets? (2000) (66)
- Macrocycles mimic the extended peptide conformation recognized by aspartic, serine, cysteine and metallo proteases. (2001) (62)
- Comparative Gene Expression Profiling of P. falciparum Malaria Parasites Exposed to Three Different Histone Deacetylase Inhibitors (2012) (62)
- Modular alpha-helical mimetics with antiviral activity against respiratory syncitial virus. (2006) (62)
- Homogeneous catalysis: catalytic intramolecular conversion of 1,4-dialdehydes to .gamma.-lactones (1990) (62)
- Histone deacetylase inhibitors and periodontal bone loss. (2011) (62)
- Towards histone deacetylase inhibitors as new antimalarial drugs. (2012) (61)
- Characterization of Copper Interactions with Alzheimer Amyloid β Peptides (2000) (60)
- Mutagenesis of the West Nile virus NS2B cofactor domain reveals two regions essential for protease activity. (2008) (59)
- An overview on the identification of MAIT cell antigens (2018) (58)
- Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis. (2015) (58)
- Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. (2000) (57)
- Conformational homogeneity in molecular recognition by proteolytic enzymes (1999) (57)
- Species Dependence for Binding of Small Molecule Agonist and Antagonists to the C5a Receptor on Polymorphonuclear Leukocytes (2001) (56)
- The Role of the N-terminal Domain of the Complement Fragment Receptor C5L2 in Ligand Binding* (2006) (56)
- Lysine Acetylation in Sexual Stage Malaria Parasites Is a Target for Antimalarial Small Molecules (2014) (56)
- Diverse MR1-restricted T cells in mice and humans (2019) (55)
- Pathway‐selective antagonism of proteinase activated receptor 2 (2014) (54)
- Beta-strand mimicking macrocyclic amino acids: templates for protease inhibitors with antiviral activity. (2002) (54)
- Site-directed Mutagenesis and Kinetic Studies of the West Nile Virus NS3 Protease Identify Key Enzyme-Substrate Interactions* (2005) (54)
- IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection (2019) (54)
- cis-Platinum(II) amine complexes: some structure-activity relationships for immunosuppressive, nephrotoxic and gastrointestinal (side) effects in rats. (1980) (53)
- The First Solution Stucture of a Single α-Helical Turn. A Pentapeptide α-Helix Stabilized by a Metal Clip (2000) (53)
- Profiling Gene Expression Induced by Protease-Activated Receptor 2 (PAR2) Activation in Human Kidney Cells (2010) (52)
- Models for Arginine-Metal Binding. Synthesis of Guanidine and Urea Ligands through Amination and Hydration of a Cyanamide Ligand Bound to Platinum(II), Osmium(III), and Cobalt(III). (1997) (52)
- A divergent transcriptional landscape underpins the development and functional branching of MAIT cells (2019) (52)
- Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets. (2015) (52)
- Comparative Agonist/Antagonist Responses in Mutant Human C5a Receptors Define the Ligand Binding Site* (2005) (52)
- Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode. (1996) (52)
- Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from alpha-aminosuberic acid. (2006) (52)
- Stereoelectronic effects dictate molecular conformation and biological function of heterocyclic amides. (2014) (51)
- Ex Vivo Activity of Histone Deacetylase Inhibitors against Multidrug-Resistant Clinical Isolates of Plasmodium falciparum and P. vivax (2010) (50)
- An Inhibitor of Phospholipase A2 Group IIA Modulates Adipocyte Signaling and Protects Against Diet-Induced Metabolic Syndrome in Rats (2012) (50)
- Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX‐1 and COX‐2 selective inhibitors, and an LTC4 receptor antagonist (2003) (49)
- Binding of Copper(II) to the Cyclic Octapeptide Patellamide D (1994) (48)
- Consecutive cyclic pentapeptide modules form short alpha-helices that are very stable to water and denaturants. (2004) (48)
- Conformationally homogeneous cyclic tetrapeptides: useful new three-dimensional scaffolds. (2003) (47)
- Conformational control by thiazole and oxazoline rings in cyclic octapeptides of marine origin. Novel macrocyclic chair and boat conformations (1996) (47)
- Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed. (2014) (46)
- C5a, but not C5a‐des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2 (2013) (46)
- Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A. (2012) (45)
- Amide-Iminol Tautomerism: Effect of Metalation (1994) (45)
- Development of C5a receptor antagonists. (1999) (45)
- Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides (2015) (45)
- Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis (2016) (45)
- Conformationally constrained macrocycles that mimic tripeptide beta-strands in water and aprotic solvents. (2002) (44)
- Novel cylindrical, conical, and macrocyclic peptides from the cyclooligomerization of functionalized thiazole amino acids. (2001) (44)
- Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection (2018) (44)
- Lysine Deacetylases and Regulated Glycolysis in Macrophages. (2018) (43)
- Truncated and Helix-Constrained Peptides with High Affinity and Specificity for the cFos Coiled-Coil of AP-1 (2013) (43)
- Membrane-anchored Serine Protease Matriptase Is a Trigger of Pulmonary Fibrogenesis. (2016) (42)
- The Ribosomal Protein S19 Suppresses Antitumor Immune Responses via the Complement C5a Receptor 1 (2017) (42)
- Towards isozyme-selective HDAC inhibitors for interrogating disease. (2012) (42)
- Metal clips that induce unstructured pentapeptides to be alpha-helical in water. (2009) (41)
- Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. (1999) (40)
- Countering cooperative effects in protease inhibitors using constrained beta-strand-mimicking templates in focused combinatorial libraries. (2004) (40)
- Synthesis and structural properties of patellamide A derivatives and their copper(II) compounds. (2002) (39)
- Selective hexapeptide agonists and antagonists for human complement C3a receptor. (2010) (39)
- Histone deacetylases (HDAC) in physiological and pathological bone remodelling. (2017) (39)
- Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages (2015) (39)
- An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation. (2013) (39)
- Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats. (2006) (39)
- Amide complexes of (diethylenetriamine)platinum(II) (1992) (39)
- The Solution Structure of a Copper(II) Compound of a New Cyclic Octapeptide by EPR Spectroscopy and Force Field Calculations. (1998) (38)
- Inhibition of Inflammation and Fibrosis by a Complement C5a Receptor Antagonist in DOCA-Salt Hypertensive Rats (2011) (38)
- Regioselective Structural and Functional Mimicry of Peptides - Design of Hydrolytically-Stable Cyclic Peptidomimetic Inhibitors of Hiv-1 Protease (1995) (38)
- A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells (2018) (38)
- Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists. (2015) (38)
- Tumor selectivity and transcriptional activation by azelaic bishydroxamic acid in human melanocytic cells. (1997) (38)
- Inhibition of immune‐complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (2001) (38)
- Crystal Structures of Protein-Bound Cyclic Peptides. (2019) (37)
- A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug. (2003) (37)
- A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis. (2005) (37)
- Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists (2016) (36)
- Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components. (2010) (36)
- Template assembled synthetic proteins (TASPS). Are template size, shape, and directionality important in formation of four-helix bundles? (1998) (36)
- Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site (2000) (35)
- Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence. (2015) (34)
- Conformations of cyclic octapeptides and the influence of heterocyclic ring constraints upon calcium binding (2000) (34)
- Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins. (2018) (34)
- Biased Signaling by Agonists of Protease Activated Receptor 2. (2017) (34)
- PAR2-induced inflammatory responses in human kidney tubular epithelial cells. (2013) (33)
- Substrate specificity of recombinant dengue 2 virus NS2B-NS3 protease: influence of natural and unnatural basic amino acids on hydrolysis of synthetic fluorescent substrates. (2007) (33)
- Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2. (2020) (33)
- Cyclooligomerization of Thiazole-Containing Tetrapeptides. Symmetrical Macrocycles with up to 76 Amino Acids (1999) (33)
- Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice. (2010) (32)
- Helix Nucleation by the Smallest Known α-Helix in Water. (2016) (32)
- The possible origin of free radicals from amyloid beta peptides in Alzheimer's disease. (1999) (32)
- Constraining Cyclic Peptides to Mimic Protein Structure Motifs (2015) (31)
- Inhibitors selective for HDAC6 in enzymes and cells. (2010) (31)
- Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. (2018) (31)
- Hydroxyquinones are competitive non-peptide inhibitors of HIV-1 proteinase. (1995) (31)
- The molecular basis underpinning the potency and specificity of MAIT cell antigens (2020) (31)
- Metal clips induce folding of a short unstructured peptide into an alpha-helix via turn conformations in water. Kinetic versus thermodynamic products. (2004) (31)
- Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1 (2020) (30)
- Solution structures in aqueous SDS micelles of two amyloid beta peptides of A beta(1-28) mutated at the alpha-secretase cleavage site (K16E, K16F). (2000) (30)
- Downsizing a human inflammatory protein to a small molecule with equal potency and functionality (2013) (30)
- Structural mimicry of two cytochrome b(562) interhelical loops using macrocycles constrained by oxazoles and thiazoles. (2005) (30)
- Synthesis, characterization, and reactivity of the (.eta.2-acetone)pentaammineosmium(II) complex (1986) (30)
- Proteases Universally Recognize β Strands in Their Active Sites (2005) (30)
- Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli (2020) (30)
- MAIT Cells Upregulate α4β7 in Response to Acute Simian Immunodeficiency Virus/Simian HIV Infection but Are Resistant to Peripheral Depletion in Pigtail Macaques (2019) (29)
- The use of live-animal micro-computed tomography to determine the effect of a novel phospholipase A2 inhibitor on alveolar bone loss in an in vivo mouse model of periodontitis. (2009) (29)
- Anti-inflammatory activity of the isoquinoline alkaloid, tetrandrine, against established adjuvant arthritis in rats (1994) (29)
- A Novel Bicyclic Enzyme Inhibitor as a Consensus Peptidomimetic for the Receptor-Bound Conformations of 12 Peptidic Inhibitors of HIV-1 Protease (1996) (29)
- Mimetics of the peptide beta-strand. (2002) (29)
- Antifibrotic Activity of an Inhibitor of Group IIA Secretory Phospholipase A2 in Young Spontaneously Hypertensive Rats (2006) (28)
- Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfide oxidases (2013) (27)
- A Novel Potassium-Binding Hydrolysis Product of Ascidiacyclamide: A Cyclic Octapeptide Isolated from the Ascidian Lissoclinum patella. (1996) (27)
- Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a (2017) (27)
- Formation of mononuclear and chloro-bridged binuclear copper(II) complexes of patellamide D, a naturally occurring cyclic peptide: influence of anion and solvent. (2004) (27)
- Lipopolysaccharide promotes Drp1‐dependent mitochondrial fission and associated inflammatory responses in macrophages (2020) (27)
- Amyloid formation from an α-helix peptide bundle is seeded by 3(10)-helix aggregates. (2011) (27)
- A peculiar toxicity manifested by platinum(II)amines in rats: gastric distension after intraperitoneal administration. (1981) (27)
- NMR solution structure of the RNA-binding peptide from human immunodeficiency virus (type 1) Rev. (1995) (27)
- THE SOLUTION STRUCTURE OF AMYLOID BETA-PEPTIDE (1-40) IN A WATER-MICELLE ENVIRONMENT. IS THE MEMBRANE-SPANNING DOMAIN WHERE WE THINK IT IS? NMR, 10 STRUCTURES (1998) (27)
- A Cyclic Metallopeptide Induces α Helicity in Short Peptide Fragments of Thermolysin (2003) (26)
- Non-peptidic anti-AIDS agents: inhibition of HIV-1 proteinase by disulfonates. (1992) (26)
- Left- and right-handed alpha-helical turns in homo- and hetero-chiral helical scaffolds. (2009) (26)
- Amination of coordinated nitriles: synthesis of metal complexes of amidines and guanidines (1990) (26)
- Interaction of zinc(II) with the cyclic octapeptides, cyclo[Ile(Oxn)-D-Val(Thz)](2) and ascidiacyclamide, a cyclic peptide from Lissoclinum patella (1999) (26)
- Cyclic octapeptides containing thiazole. Effect of stereochemistry and degree of flexibility on calcium binding properties (2002) (25)
- Therapeutic targets in inflammatory disease. (2005) (25)
- Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseases (2012) (24)
- Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints. (2003) (24)
- Downsizing Proto-oncogene cFos to Short Helix-Constrained Peptides That Bind Jun. (2017) (24)
- Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infection (2020) (24)
- Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion (2021) (24)
- Synthesis, solution structure, and reactivity of oxygen-bound amides on cobalt(III) (1993) (24)
- Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens (2020) (24)
- MAIT cells regulate NK cell-mediated tumor immunity (2020) (24)
- Electrophilic Helical Peptides That Bond Covalently, Irreversibly, and Selectively in a Protein-Protein Interaction Site. (2017) (23)
- Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes (2013) (23)
- Organic azide inhibitors of cysteine proteases. (2006) (23)
- Over One Hundred Peptide‐Activated G Protein‐Coupled Receptors Recognize Ligands with Turn Structure (2005) (23)
- Oxygen versus nitrogen coordination of a urea to (diethylenetriamine)platinum(II) (1993) (23)
- Virus-Mediated Suppression of the Antigen Presentation Molecule MR1 (2020) (22)
- Generation and characterization of proteolytically active and highly stable truncated and full-length recombinant West Nile virus NS3. (2007) (22)
- Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease (2015) (22)
- Protease-Activated Receptor-2 Peptides Activate Neurokinin-1 Receptors in the Mouse Isolated Trachea (2006) (22)
- An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice (2017) (22)
- Base-catalyzed hydration of cobalt(III)-coordinated dimethylcyanamide and linkage isomerization of the derived N-bound dimethylurea complex (1983) (22)
- Potent heterocyclic ligands for human complement c3a receptor. (2014) (22)
- New Treatment Strategies for Dengue and other Flaviviral Diseases (2006) (22)
- Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis (2018) (22)
- Small molecule inhibitors of disulfide bond formation by the bacterial DsbA-DsbB dual enzyme system. (2015) (22)
- Development of cell‐penetrating peptide‐based drug leads to inhibit MDMX:p53 and MDM2:p53 interactions (2016) (21)
- Catalytically active Dengue virus NS3 protease forms aggregates that are separable by size exclusion chromatography. (2002) (21)
- Macrocyclic peptidomimetics: potential for drug development. (1998) (21)
- Profiling the Enzymatic Properties and Inhibition of Human Complement Factor B* (2007) (21)
- Irritancy and anti-inflammatory activity of bis(eta 5-cyclopentadienyl)titanium(IV) complexes in rats. (1987) (21)
- Factors Influencing the Nitrogen Vs Oxygen Bonding Mode of Amides Bound to Pentaamminecobalt(Iii) and the Kinetics and Mechanism of Rearrangement (1991) (21)
- Protease activated receptor 2 (PAR2) modulators: a patent review (2010–2015) (2016) (20)
- Inhibition of immune‐complex mediated dermal inflammation in rats following either oral or topical administration of a small molecule C5a receptor antagonist (2002) (20)
- Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles. (2002) (20)
- Inhibition of HIV-1 proteinase by non-peptide carboxylates. (1991) (19)
- Antiproliferative and phenotype-transforming antitumor agents derived from cysteine. (2004) (19)
- C5aR and C5L2 act in concert to balance immunometabolism in adipose tissue (2014) (19)
- Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability. (2018) (19)
- Protein α-turns recreated in structurally stable small molecules. (2011) (19)
- A refined agonist pharmacophore for protease activated receptor 2. (2007) (18)
- Oxygen versus Nitrogen Bonding of Carboxamides to Pentaammineruthenium(II/III). (1997) (18)
- An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein. (2013) (18)
- Crystal structures of highly constrained substrate and hydrolysis products bound to HIV-1 protease. Implications for the catalytic mechanism. (2008) (18)
- Noncovalent tripeptidyl benzyl- and cyclohexyl-amine inhibitors of the cysteine protease caspase-1. (2010) (18)
- Potent Small Agonists of Protease Activated Receptor 2. (2016) (18)
- Activation of Thiourea Bound through Sulfur to Pentaammineruthenium(III): Structure and Reactivity. (1997) (17)
- Simultaneous uncoupled expression and purification of the Dengue virus NS3 protease and NS2B co-factor domain. (2016) (17)
- Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling. (2017) (17)
- Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. (2018) (16)
- Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease‐activated receptor‐2 (2016) (16)
- Zinc monoglycerolate — A slow-release source of therapeutic zinc: Solubilization by endogenous ligands (1992) (16)
- Quinazolinone derivatives as inhibitors of homologous recombinase RAD51. (2017) (16)
- Chemically Diverse Helix-Constrained Peptides Using Selenocysteine Crosslinking. (2018) (16)
- Organization of amino acids using a metallotriazacyclononane template (1997) (16)
- Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists. (2015) (16)
- Platinum drugs: Combined anti-lymphoproliferative and nephrotoxicity assay in rats (1980) (16)
- Tolyporphin Macrocycles from the Cyanobacterium Tolypothrix nodosa Selectively Bind Copper and Silver and Reverse Multidrug Resistance. (2017) (16)
- Synthesis of the thiazole-thiazoline fragment of largazole analogues. (2011) (16)
- Connecting hydrophobic surfaces in cyclic peptides increases membrane permeability. (2020) (16)
- Inhibitors of beta-amyloid formation based on the beta-secretase cleavage site. (2000) (15)
- Crystal Structure of the Dithiol Oxidase DsbA Enzyme from Proteus Mirabilis Bound Non-covalently to an Active Site Peptide Ligand (2014) (15)
- Biphasic Response of the Metallothionein Promoter to Ultraviolet Radiation in Human Melanoma Cells (1997) (15)
- Linkage isomerization of (urea)pentaammineruthenium(III) and inter- vs. intramolecular substitution on ruthenium(III) (1985) (15)
- Targeting quorum sensing and competence stimulation for antimicrobial chemotherapy. (2012) (15)
- A dual-purpose synthetic colloidal platform for protease mapping: substrate profiling for Dengue and West Nile virus proteases. (2008) (15)
- Diet-induced obesity , adipose inflammation , and metabolic dysfunction correlating with PAR 2 expression are attenuated by PAR 2 antagonism (2013) (15)
- Nonpeptide ligands that target peptide-activated GPCRs in inflammation. (2005) (15)
- C5a Receptor (CD88) Inhibition Improves Hypothermia-Induced Neuroprotection in an In Vitro Ischemic Model (2012) (15)
- Inhibitors of class I histone deacetylases attenuate thioacetamide‐induced liver fibrosis in mice by suppressing hepatic type 2 inflammation (2019) (15)
- A cyclic beta-strand tripeptide with an alpha-helix like CD spectrum. (2009) (15)
- Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery (2015) (15)
- CXCL16 Stimulates Antigen-Induced MAIT Cell Accumulation but Trafficking During Lung Infection Is CXCR6-Independent (2020) (14)
- Inhibition of HIV-1 proteinase by metal ions. (1992) (14)
- Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor. (2001) (14)
- Nonpeptidic Ligands for Peptide-Activated G Protein-Coupled Receptors (2007) (14)
- Ammonia and carbon dioxide from urea. A multinuclear NMR study of the activation of urea by platinum(II) (1995) (13)
- Regulators of the anaphylatoxin C5a (2000) (13)
- Protease activated receptor 2 controls myelin development, resiliency and repair (2017) (13)
- Structure-activity relationships for substrate-based inhibitors of human complement factor B. (2009) (13)
- Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity. (2020) (13)
- A novel long-range n to π* interaction secures the smallest known α-helix in water. (2019) (13)
- Efficient chemical synthesis of human complement protein C3a. (2013) (13)
- Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro (2020) (12)
- Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection (2021) (12)
- An efficient Fmoc strategy for the rapid synthesis of peptide para-nitroanilides (2000) (12)
- A Convergent Solution‐Phase Synthesis of the Macrocycle Ac‐Phe‐[Orn‐Pro‐D‐Cha‐Trp‐Arg], a Potent New Antiinflammatory Drug. (2003) (12)
- Downsizing the BAD BH3 peptide to small constrained α-helices with improved ligand efficiency. (2016) (12)
- Anti–Inflammatory activity of a holothurian (sea cucumber) food supplement in rats (1994) (12)
- A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling (2012) (12)
- Cobalt-induced facile degradation of phenylurea to ammonia, carbon dioxide, and anilinium ion and other reactions of linkage isomeric cobalt(III) complexes of phenylurea (1989) (12)
- Unexpected photolytic decomposition of alkyl azides under mild conditions. (2007) (12)
- The α-Proteobacteria Wolbachia pipientis Protein Disulfide Machinery Has a Regulatory Mechanism Absent in γ-Proteobacteria (2013) (12)
- Linkage isomerization of (formamide-N)- and (acetamide-N)pentaamminecobalt(III) ions in water, dimethyl sulfoxide, and sulfolane (1990) (12)
- Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease (1996) (11)
- HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks (2012) (11)
- A Selective and Versatile Synthesis of Substituted Chromones via Addition of Phenols to Dimethyl Acetylenedicarboxylate (1995) (11)
- Mapping transmembrane residues of proteinase activated receptor 2 (PAR2) that influence ligand‐modulated calcium signaling (2017) (11)
- Computer modelling and synthesis of deoxy and monohydroxy analogues of a ribitylaminouracil bacterial metabolite that potently activates human T cells. (2019) (11)
- SOLUTION STRUCTURE OF THE METHIONINE-OXIDIZED AMYLOID BETA-PEPTIDE (1-40). DOES OXIDATION AFFECT CONFORMATIONAL SWITCHING? NMR, 10 STRUCTURES (1998) (11)
- Reversible linkage isomerization of pentaamminecobalt(III) complexes of urea and its N-methyl derivatives (1988) (11)
- PAR2 Modulators Derived from GB88. (2016) (11)
- PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR (2020) (11)
- Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA (2015) (11)
- Insecticidal activities of histone deacetylase inhibitors against a dipteran parasite of sheep, Lucilia cuprina (2017) (10)
- A general synthetic route to pentaamminecobalt(III) complexes of N-bonded amides, ureas, carbamates, sulfinamides, sulfonamides and sulfamate (1990) (10)
- Histone deacetylase enzymes as drug targets for the control of the sheep blowfly, Lucilia cuprina (2015) (10)
- Linkage isomerism in the binding of pentapeptide Ac-His(Ala)3His-NH2 to (ethylenediamine)palladium(II): effect of the binding mode on peptide conformation. (2008) (10)
- Fortified Coiled Coils: Enhancing Mechanical Stability with Lactam or Metal Staples (2020) (10)
- Characterization of Human Mucosal‐associated Invariant T (MAIT) Cells (2019) (10)
- Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. (2009) (10)
- 'Clean' or 'Dirty' : Just How Selective do Drugs Need to Be? (2008) (9)
- Binding of the immunosuppressant peptide cyclosporine a to calcium, zinc and copper. Is cyclosporine a an ionophore? (1995) (9)
- Lymphoid suppression by cis-platinum(II) amines. What are the active agents? (1982) (9)
- PAR 2-induced inflammatory responses in human kidney tubular epithelial cells (2013) (9)
- Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro* (2016) (9)
- Human MAIT cells respond to and suppress HIV-1 (2021) (9)
- Product release is rate-limiting for catalytic processing by the Dengue virus protease (2016) (9)
- Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-Resistant and Intracellular Mycobacterium tuberculosis (2019) (8)
- Thiazoles in Peptides and Peptidomimetics (2015) (8)
- Transdermal delivery of inorganic complexes as metal drugs or nutritional supplements. (1991) (8)
- Atypical TRAV1-2− T cell receptor recognition of the antigen-presenting molecule MR1 (2020) (8)
- Folding pentapeptides into left and right handed alpha helices (2012) (8)
- Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles. (2003) (8)
- Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition. (2017) (8)
- Studies of the interaction of potassium(I), calcium(II), magnesium(II), and copper(II) with cyclosporin A. (2003) (8)
- Cell phenotype as a target of drug therapy in chronic inflammatory diseases. (2000) (8)
- Repurposing Registered Drugs as Antagonists for Protease-Activated Receptor 2 (2015) (8)
- Nitrogen- and oxygen-bonded urethane: hydrolysis and linkage isomerization of [(NH3)5Co(NH2CO2C2H5)]3+ and [(NH3)5CoOC(NH2)OCH2CH3]3+ (1990) (8)
- Characterization and Purification of Mouse Mucosal‐Associated Invariant T (MAIT) Cells (2019) (8)
- MR1-Restricted T Cells with MAIT-like Characteristics Are Functionally Conserved in the Pteropid Bat Pteropus alecto (2020) (8)
- Matching Cavities in G Protein-Coupled Receptors to Infer Ligand-Binding Sites (2012) (8)
- Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation. (2020) (8)
- Hepta and octapeptide agonists of protease‐activated receptor 2 (2007) (8)
- Identification and characterization of bi-thiazole-2,2'-diamines as kinase inhibitory scaffolds. (2013) (8)
- Toward peptide-based inhibitors as therapies for Parkinson's disease. (2015) (7)
- cis-Platinum(II) amines: toxicities and immunosuppressant/anti-arthritic activities. (1981) (7)
- Helix-constrained nociceptin peptides are potent agonists and antagonists of ORL-1 and nociception. (2015) (7)
- An efficient Fmoc strategy for the rapid synthesis of peptide para-nitroanilides (2006) (7)
- Targeting Histone Deacetylase 1 (Hdac 1) to Suppress Both Inflammation and Bone Loss in Arthritis (2013) (7)
- Identification and Phenotype of MAIT Cells in Cattle and Their Response to Bacterial Infections (2020) (7)
- Facile and stereoselective condensation of acetone with ammonia ligands on cobalt(III): structure of a N-bonded cyanate complex containing the 2-methyl-2-amino-4-imino-pentane ligand (1999) (7)
- Oxygen- and sulfur-bonded thiosulfatopentaamminecobalt(III) (1983) (7)
- Europium-Labeled Synthetic C3a Protein as a Novel Fluorescent Probe for Human Complement C3a Receptor. (2017) (7)
- Chemical Approaches to Modulating Complement-Mediated Diseases. (2017) (6)
- Chemical Modulators of Mucosal Associated Invariant T Cells. (2021) (6)
- A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and Autophagy (2020) (6)
- Pharmacological inhibition of protease‐activated receptor‐2 reduces crescent formation in rat nephrotoxic serum nephritis (2019) (6)
- Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition (2020) (6)
- INHIBITORS OF CYCLO-OXYGENASE-2 AND SECRETORY PHOSPHOLIPASE A 2 (GROUP IIa) PRESERVE BONE ARCHITECTURE FOLLOWING OVARIECTOMY IN ADULT RATS (2006) (6)
- Inhibitory effects of bisbenzylisoquinolines on synthesis of the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha (1993) (6)
- Mimicking extended conformations of protease substrates (1997) (6)
- A new dinuclear amine-cobalt(III) complex containing two bridging amide ions (1993) (6)
- Glucuronic acid as a helix-inducing linker in short peptides. (2018) (6)
- Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids. (2015) (5)
- HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates. (2021) (5)
- Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships. (2015) (5)
- CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells (2022) (5)
- Simple cis-epoxide-based inhibitors of HIV-1 protease (1997) (5)
- Oxazole-Benzenesulfonamide Derivatives Inhibit HIV-1 Reverse Transcriptase Interaction with Cellular eEF1A and Reduce Viral Replication (2019) (5)
- PAR2 Activation on Human Kidney Tubular Epithelial Cells Induces Tissue Factor Synthesis, That Enhances Blood Clotting (2021) (5)
- Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake (2022) (5)
- Structure of a novel protonated oxadiazine: an unusual heterocycle from the cycloaddition of a ketone with nitriles (1996) (5)
- QSAR Classification Models for Prediction of Hydroxamate Histone Deacetylase Inhibitor Activity against Malaria Parasites. (2022) (4)
- Beta‐Strand Mimetics (2005) (4)
- Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides (2022) (4)
- Benzylamide antagonists of protease activated receptor 2 with anti-inflammatory activity. (2016) (4)
- Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages (2022) (4)
- WEST NILE VIRUS NS 3 PROTEASE : INSIGHTS INTO SUBSTRATE BINDING AND PROCESSING THROUGH COMBINED MODELLING , PROTEASE MUTAGENESIS AND KINETIC STUDIES (2006) (4)
- Mimicking extended conformations of protease substrates: Designing cyclic peptidomimetics to inhibit HIV-1 protease (1997) (4)
- Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities. (2019) (4)
- Discovery of Potent Cyclic Antagonists of Human C5a Receptors (2005) (4)
- Linkage Isomeric Pentaamminecobalt(Iii) Complexes of Methanesulfinamide (1990) (4)
- Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease. (2022) (4)
- A Novel Long‐Range n to π* Interaction Secures the Smallest known α‐Helix in Water (2019) (4)
- Alpha helix nucleation by a simple cyclic tetrapeptide (2016) (4)
- Protease Inhibitors: Current Status and Future Prospects (2000) (4)
- Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate (2021) (4)
- Helical cyclic pentapeptides constrain HIV-1 Rev peptide for enhanced RNA binding (2014) (4)
- Conformational Control by Thiazole and Oxazoline Rings in Cyclic Octapeptides of Marine Origin. Novel Macrocyclic Chair and Boat Conformations. (1997) (4)
- Current approaches to peptidomimetics (2003) (4)
- Characterisation of TNF-α-related peptides by high-performance liquid chromatography-mass spectrometry and high-performance liquid chromatography-tandem mass spectrometry (1993) (3)
- Mimetics of the Peptide β‐Strand (2003) (3)
- Connecting Hydrophobic Surfaces in Cyclic Peptides Increases Membrane Permeability (2020) (3)
- Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines (2021) (3)
- Editorial [Hot Topic: Latest Developments in the Treatment of Inflammatory Disease (Guest Editor: David Fairlie)] (2005) (3)
- Homogeneous Catalysis: Catalytic Intramolecular Conversion of 1,4‐Dialdehydes to γ‐Lactones. (1990) (3)
- Towards Protein Surface Mimetics (1998) (3)
- PAR2-Induced Tissue Factor Synthesis by Primary Cultures of Human Kidney Tubular Epithelial Cells Is Modified by Glucose Availability (2021) (3)
- Phospholipase A2 inhibitor attenuates NOx production and myocardial damage in the cardiac allograft (2002) (3)
- Cyclooligomerization of a helix-bearing template into macrocycles bearing multiple helices. (2008) (2)
- Protease‐activated receptor 2 does not contribute to renal inflammation or fibrosis in the obstructed kidney (2019) (2)
- The histone deacetylase Hdac7 supports LPS‐inducible glycolysis and Il‐1β production in murine macrophages via distinct mechanisms (2021) (2)
- Synthesis, solution structure, and reactivity of oxygen-bound amides on cobalt(III). [Erratum to document cited in CA118(14):138542q] (1993) (2)
- Targeting Class IIa HDACs: Insights from Phenotypes and Inhibitors. (2021) (2)
- The balance of interleukin‐12 and interleukin‐23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection (2022) (2)
- Small Molecules that Mimic Components of Bioactive Protein Surfaces (2004) (2)
- Cobalt-induced facile degradation of phenylurea to ammonia, carbon dioxide, and anilinium ion and other reactions of linkage isomeric cobalt(III) complexes of phenylurea [Erratum to document cited in CA110(22):199921u] (1990) (2)
- Activation of protease‐activated receptor 2 is associated with blood pressure regulation and proteinuria reduction in metabolic syndrome (2020) (2)
- Structures of peptide agonists for human protease activated receptor 2. (2012) (2)
- Legionella protection and vaccination mediated by Mucosal Associated Invariant T (MAIT) cells (2017) (2)
- A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells (2022) (2)
- De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex (2020) (2)
- Ligand-induced dimerisation of the complement C5aR and C5L2 receptors by C5a but not C5a-des Arg (2012) (2)
- PANCREATIC SECRETORY PHOSPHOLIPASE A2 (IIa) WITH ANTI-INFLAMMATORY ACTIVITY (2003) (2)
- Non-peptide inhibitors of HIV-1 protease. Synthesis and structural evaluation of symmetric and non-symmetric naphthalenesulfonic acid analogues (1996) (2)
- Synthesis of benzoxazole-based vorinostat analogs and their antiproliferative activity. (2021) (1)
- Differential location of NKT and MAIT cells within lymphoid tissue (2021) (1)
- A cyclic metallopeptide induces alpha helicity in short peptide fragments of thermolysin. (2003) (1)
- Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma (2018) (1)
- Complement Promotes Gvhd through Suppressing Autophagy in Recipient Dendritic Cells after Allogeneic Hematopoietic Cell Transplantation in Mice (2017) (1)
- Novel agonists and antagonists for protease activated receptor 2 (2011) (1)
- Targeting Host Complement C3a/C5a Receptors to Control of Acute Graft-Versus-Host Disease in Mice (2015) (1)
- Late‐Stage Hydrocarbon Conjugation and Cyclisation in Synthetic Peptides and Proteins (2021) (1)
- Treatment of osteoarthritis (2005) (1)
- Diverse MR1-restricted T cells in mice and humans (2019) (1)
- Editorial (Hot Topic: Chemical Biology Down Under) (2012) (1)
- Small peptides Do not inhibit human non-pancreatic secretory phospholipase-A(2) (Type IIA). (2000) (1)
- High Cell Permeability Does Not Predict Oral Bioavailability for Analogues of Cyclic Heptapeptide Sanguinamide A (2020) (1)
- MAIT cells protect against pulmonary Legionella longbeachae infection (2018) (1)
- Altering T-Cell Responses in the Metastatic Niche Complement C 5 a Receptor Facilitates Cancer Metastasis (2014) (1)
- Synthesis, characterization, and reactivity of the (η2-acetone)pentaammineosmium(II) complex (1987) (1)
- Parallel synthesis af anticancer, antiinflammatory and antiviral agents derived from L- and D- amino acids (2008) (1)
- A Selective and Versatile Synthesis of Substituted Chromones via Addition of Phenols to Dimethyl Acetylenedicarboxylate. (1995) (1)
- Shedding light on MHC class I antigen loading: a UV-labile peptide ligand approach (2012) (1)
- Recent Advances in β‐Strand Mimetics (2011) (1)
- Designing metalloinhibitors for delivery to peptide receptors in enzymes. (1993) (1)
- Corrections to Selective Hexapeptide Agonists and Antagonists for Human Complement C3a Receptor (2010) (1)
- Base-Sensitivity of Arginine Alpha-Ketoamide Inhibitors of Serine Proteases (2009) (1)
- Plasmodium falciparum histone deacetylases: enzymes involved in gene regulation as new antimalarial drug targets (2007) (1)
- Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice (2021) (1)
- Hydrolases (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (1)
- Short peptide alpha helices induced by multiple metal clips (2003) (1)
- Regioselective Structural and Functional Mimicry of Peptides. Design of Hydrolytically-Stable Cyclic Peptidomimetic Inhibitors of HIV-1 Protease. (1996) (1)
- This information is current as in Macrophages by Complement Protein C5a Primary Human Monocytes but Suppressed Lipopolysaccharide Are Amplified in Inflammatory Responses Induced by (2014) (0)
- Inhibiting Histone Deacetylases Expressed in Human Periodontal Tissues Prevents Bone Loss in An Animal Model of Periodontal Disease (2011) (0)
- Heterocycles for switching GPCR ligand conformation and activity (2019) (0)
- New amino acid derivatives useful for the treatment of inflammatory disease or condition e.g. rheumatic arthritis (2007) (0)
- Conformationally constrained small molecule antagonists of C5a. (1997) (0)
- Design and synthesis of new cavitands which are stereochemically rigid, hydrophobic and internally functionalised (1992) (0)
- Multifrequency EPR spectra of Cu(II) and Ag(II) tolyporphins (1995) (0)
- Homogeneous Catalysis. Conversion of 4-Pentenals to Cyclopentanones by Efficient Rhodium-Catalyzed Hydroacylation. (1988) (0)
- Development of a catalytically active recombinant West Nile NS3 protease and the identification of key enzyme-substrate interactions by site-directed mutagenesis (2005) (0)
- A Novel Protease-Activated Receptor-2 Antagonist Targeting Inflammation and Proliferation in Human Renal Tubular Epithelial Cells (2010) (0)
- Hydrolases (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (0)
- Construction and characterization of the dengue 2 virus NS3 protease and its mutants (2001) (0)
- Spontaneously Hypertensive Rats in Young 2 IIA Secretory Phospholipase A Antifibrotic Activity of an Inhibitor of Group (2006) (0)
- Multiple targets for antiviral inhibitors (2006) (0)
- Concise synthesis of the thiazole-thiazoline fragment of largazole (2012) (0)
- MAIT cells: Friend or Foe in recognising microbial vitamin metabolites presented by the MHC-I-related molecule MR1 (2016) (0)
- Priming programed Mucosal-Associated Invariant T cells protect against systemic or local bacterial infection (2020) (0)
- Effect of a protease-activated receptor-2 antagonist (GB88) on inflammation-related loss of alveolar bone in periodontal disease. (2023) (0)
- Design and synthesis of inhibitors of HIV-1 protease (1994) (0)
- A novel strategy for the design of potent peptidomimetic inhibitors of proteolytic enzymes: Application to HIV-1 protease. (1997) (0)
- Drugs and drug-like molecules can modulate mucosal-associated invariant T cell function (2017) (0)
- The complement C5a receptor facilitates cancer metastasis by altering T cell responses in metastases-targeted organs (TUM2P.883) (2014) (0)
- Prevention of ischemia/reperfusion injuries in rats by a new small molecule C5a receptor antagonist (2001) (0)
- Towards Modular Alpha-Helices: Comformationally Stable Cyclic Pentapeptides as Alpha-Turn Mimetics (2004) (0)
- Catalyst‐Free N‐Arylation Using Unactivated Fluorobenzenes. (2013) (0)
- Inhibition of both class I and class II histone deacetylases is required to effectively inhibit osteoclast bone resorption in vivo and in vitro (2009) (0)
- Front Cover: Late‐Stage Hydrocarbon Conjugation and Cyclisation in Synthetic Peptides and Proteins (ChemBioChem 10/2021) (2021) (0)
- Structure of human MAIT TCR in complex with human MR1-6-FP (2013) (0)
- Metal clips for folding peptides (2001) (0)
- The molecular basis underpinning the potency and specificity of MAIT cell antigens (2020) (0)
- Mining physicochemical features that contribute to oral bioavailability in peptide middle space (2014) (0)
- Abstract 15: The Novel Complement C3ar Antagonist Jr14a Is Neuroprotective In Stroke (2022) (0)
- Symmetrical and Nonsymmetrical Nonpeptide Inhibitors of Hiv-1 Protease - Naphthalenesulfonic Acid-Derivatives (1993) (0)
- Metallopeptides in Alzheimer's Disease (2000) (0)
- Helix inducing metal clips in short peptides (2003) (0)
- Novel inhibitors of DENV NS2B/NS3pro protease (2013) (0)
- How MAIT cells control the growth of intracellular mycobacteria (P4381) (2013) (0)
- Inhibition of Human Secretory Phospholipase A2 (Type IIA) (2000) (0)
- A broad family of MR1-restricted T cells (2016) (0)
- Over 100 peptide-activated GPCRS recognize turn motifs in ligands (2005) (0)
- Structure of a Novel Protonated Oxadiazine: An Unusual Heterocycle from the Cycloaddition of a Ketone with Nitriles. (1996) (0)
- Drugs/drug analogues modulate MAIT cell function in an MR1-dependent manner (2016) (0)
- Development of a catalytically active recombinant West Nile virus NS3 protease and the identification of key enzyme-substrate and enzyme-cofactor interactions by site-directed mutagenesis (2005) (0)
- Characterization of the alpha-proteobacteria Wolbachia pipientis protein disulphide machinery reveals a regulatory mechanism absent in gamma-proteobacteria (2014) (0)
- Towards orally bioavailable peptides and peptidomimetics (2011) (0)
- An interaction between the methyltransferase and RNA dependent RNA polymerase 1 domains of the West Nile virus NS 5 protein 2 Running title : An interaction between the WNV NS 5 MTase-POL 3 (2013) (0)
- Modelling of the C5a receptor by iterative mutation (2010) (0)
- Defining the ligand binding site on the human C5a receptor (2006) (0)
- Regulating protein and peptide activated GPCRs (2009) (0)
- MEDI 181-Alpha helix induction in HIV REV34-50 by N-terminal nucleators (2006) (0)
- Vitamin B2 related molecules that activate T cells (2017) (0)
- Reversible Linkage Isomerization of Pentaamminecobalt(III) Complexes of Urea and Its N-Methyl Derivatives. (1988) (0)
- HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. (2023) (0)
- Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation (2019) (0)
- Fluorobenzene derivatives as multifunctional tools (2012) (0)
- Validation of non-invasive transcutaneous method for glomerular filtration rate (GFR) in obese mice (2018) (0)
- Modelling studies of molecular receptors (1998) (0)
- Correction: Downsizing the BAD BH3 peptide to small constrained α-helices with improved ligand efficiency. (2016) (0)
- Stereoelectronic Effects on Dienophile Separation Influence the Diels–Alder Synthesis of Molecular Clefts (2017) (0)
- Amination of Coordinated Nitriles: Synthesis of Metal Complexes of Amidines and Guanidines. (1990) (0)
- New cyclic peptide or peptidomimetic compounds, are G-protein coupled receptor antagonists useful for treating inflammatory disorders such as rheumatoid arthritis, reperfusion injury or dermal inflammation (2003) (0)
- DNA damage- induced apoptosis in the BL30A Burkitt’s lymphoma cell line requires caspase-8 and mitochondrial p53 activity. (2011) (0)
- Downsizing Proteins Without Losing Potency or Function (2015) (0)
- COMP 264-Unraveling the mechanism of antagonism for human C5a receptor: Comparison of three structurally different antagonists (2008) (0)
- Structure of human MAIT TCR in complex with human MR1-RL-6-Me-7-OH (2013) (0)
- Conformations of Cyclic Octapeptides and the Influence of Heterocyclic Ring Constraints Upon Calcium Binding. (2000) (0)
- Organic Azide Inhibitors of Cysteine Proteases [J. Am. Chem. Soc. 2006, 128, 12396−12397]. (2007) (0)
- Tetramer identification of functional mouse mucosal associated invariant T cells (INC6P.352) (2014) (0)
- Investigation of the West Nile virus NS3 protease by tandem use of site-directed mutagenesis and substrate modification (2006) (0)
- Potent inhibitors of West Nile Virus NS2B/NS3 protease (2009) (0)
- Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages (2023) (0)
- Multifrequency EPR studies of the mono- and bi-nuclear copper(II) complexes formed with the marine cyclic octapeptides patellamide D and ascidiacyclamide (1996) (0)
- “Clean” or “Dirty” — Just How Selective Do Drugs Need to Be? (2009) (0)
- Cyclic Octapeptides Containing Thiazole. Effect of Stereochemistry and Degree of Flexibility on Calcium Binding Properties. (2010) (0)
- Simple cis‐Epoxide‐Based Inhibitors of HIV‐1 Protease. (1998) (0)
- Genome wide expression profiling of hydroxamate-based HDAC inhibitors against P. falciparum (2010) (0)
- Characterisation of TNF-alpha-related peptides by high-performance liquid chromatography-mass spectrometry and high-performance liquid chromatography-tandem mass spectrometry. (1993) (0)
- Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a (2017) (0)
- Developing antiviral targets for RSV via mutational analysis of HRB and HRC domains using a novel fusion assay system (2006) (0)
- Erratum to “Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites” [Int. J. Parasitol. Drugs Drug Res. 5 (2015) 117–126] (2016) (0)
- Supplementary Figure S1 for AJP-Renal submission (2019) (0)
- Linkage Isomerization of (Urea)pentaammineruthenium(III) and Inter- vs. Intramolecular Substitution on Ruthenium(III). (1986) (0)
- Template-assembled peptide loops, helices, sheets, and nanofibers (2003) (0)
- Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles. (2022) (0)
- Tetramer identification of functional mouse mucosal associated invariant T (MAIT) cells (2015) (0)
- Palladium induced alpha helicity in short peptides. (2002) (0)
- The reaction between metal ions and short peptides (2000) (0)
- Tumor‐Associated Antigenic Peptides as Vaccine Candidates (2009) (0)
- Toward more orally bioavailable inhibitors of phospholipase A(2) GIIA (pla2g2a) to treat chronic inflammation (2013) (0)
- Common drugs modulate mucosal-associated invariant T cell function (2016) (0)
- Conformationally constrained cyclic mimetics of protein and peptide surfaces. (1997) (0)
- THE LIVER IN THE REGULATION OF IRON HOMEOSTASIS : ROLE OF HEPCIDIN AND TRANSFERRIN RECEPTOR 2 (2005) (0)
- Erratum: Latest developments in the treatment of inflammatory disease (Current Medicinal Chemistry (2005) vol. 12 (25) (2923-224)) (2007) (0)
- Supplementary Data tables for: Orally absorbed cyclic peptides (2019) (0)
- Molecular basis underpinning metabolite-mediated T-cell immunity (2021) (0)
- Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I–related protein 1 MR1 (2022) (0)
- Alpha-helix induction in short peptides using metal clips (2005) (0)
- MEDI 180-Effects of cyclization constraints on helix/turn peptide structures (2006) (0)
- Complement and inflammation: New antagonists of C5a receptors. (2000) (0)
- Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1-3 in mesendoderm cell differentiation. (2022) (0)
- MEDI 256-Activation and inhibition of latent serine proteases, complement factors B and C2 (2008) (0)
- MR1 dependent MAIT cell activation is regulated by autophagy associated proteins (2022) (0)
- Venom Composition and Bioactive Rf-Amide Peptide Toxins of the Saddleback Caterpillar, Acharia Stimulea (Lepidoptera: Limacodidae) (2023) (0)
- Helical structure in cyclic peptides: effect of N-methyl amides versus esters. (2022) (0)
- Editorial: chemical biology Down Under. (2012) (0)
- Coordination with Pd(en)2+ imposes an a-helical structure on a pentapeptide (2000) (0)
- Reactivity of commercially available Fmoc amino acids: supplementary information (2015) (0)
- IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infection (2019) (0)
- Deactivation of the chlorosulfonate ion coordinated to pentaamminecobalt(III) (2002) (0)
- The selective binding of tolyporphins to metal ions (1995) (0)
- Antigen-specific MAIT cell subsets involved in TB immunity (INC2P.420) (2015) (0)
- Synthesis of cavitands as catalytic environments (1991) (0)
- HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR (2000) (0)
- Thymic precursors to the mucosal-associated invariant T cell lineage (2016) (0)
- NMR solution structure for di-sulfide 11mer peptide (2015) (0)
- NMR solution structure for lactam (5,9) 11mer (2015) (0)
- Protease activated-receptor-2 induced inflammation and fibrosis is mediated in part through activation of transforming growth factor-beta signalling (2016) (0)
- HIV-1 REV PROTEIN (RESIDUES 34-50) (1995) (0)
- Recipient mucosal-associated invariant T cells control graft-versus-host-disease within the colon. (2018) (0)
- Peptide bundles: Loops, helices, strands and sheets (2006) (0)
- Inhibiting Virulence in E. coli: Screening of Peptidomimetics Ttargeting the DsbA Disulfide Bond Formation Machinery (2013) (0)
- Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc (2021) (0)
- Pharmacological Inhibition of Protease-Activated Receptor 2 (Par2) Reduces Crescent Formation in Rat Anti-Gbm Disease (2016) (0)
- NMR structure of a short hydrophobic 11mer peptide in 25 mM SDS solution (2015) (0)
- T-cell antigen formed from distinct metabolic pathways (2015) (0)
- Inhibiting, stabilising and probing the function of the Retromer endosomal trafficking complex through the novel macrocyclic peptides (2021) (0)
- Protease-activated receptor-2 and renal carcinogenesis (2010) (0)
- RESEARCH PAPER Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats (2010) (0)
- Helical Agonist of Nociceptin (NOP) Receptor (2011) (0)
- Cyclic peptides as metal ion receptors (1996) (0)
- Control of peptide conformation by Palladium(II) coordination (2001) (0)
- Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation (2023) (0)
- Towards Arginine Mimetics (2000) (0)
- NMR solution structure of oxidized KpDsbA (2013) (0)
- Tautomerism in Amide Complexes (1992) (0)
- A unified view of neighbour cell engagement during apoptotic cell extrusion (2020) (0)
- The selective binding of metal ions by tolyporphins (1997) (0)
- CB&DD Editorial Advisory Board (seventh in series) (2006) (0)
- Effects of conformational constraints in cyclic octapeptides of marine origin (1996) (0)
- Antiviral activity in cell culture of potent inhibitors targeting the West Nile Virus NS2B/NS3 protease (2009) (0)
- In vitro catalytic activity of recombinant forms of the dengue virus NS3 protease (2001) (0)
- MoleculesIs a Target for Antimalarial Small Lysine Acetylation in Sexual Stage Malaria (2014) (0)
- Sneaking up on West Nile Virus NS2B/NS3 protease subcellular activity utilising dye-quenched substrates (2010) (0)
- Are ketoamides suitable electrophilic isosteres for incorporation in inhibitors of serine proteases (2001) (0)
- Transcriptional profiling the effects of hydroxamate-based HDAC inhibitors in P. falciparum (2010) (0)
- Model of Inflammatory Bowel Disease Protects against Disease Pathology in a Rat A Potent Human C5a Receptor Antagonist (2003) (0)
- Expression and characterization of a catalytically active form of the Dengue virus NS3 protease (2000) (0)
- Conformationally restricted cyclic peptides incorporating oxazoline and thiazole ring constraints. (1998) (0)
- RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease (2018) (0)
- C5a Receptor (CD88) Inhibition Improves Hypothermia-Induced Neuroprotection in an In Vitro Ischemic Model (2012) (0)
- A General Synthetic Route to Pentaamminecobalt(III) Complexes of N- Bonded Amides, Ureas, Carbamates, Sulfinamides, Sulfonamides and Sulfamate. (1991) (0)
- Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition (2020) (0)
- Activity of the histone deacetylase (HDAC) inhibitor AR-42 in a murine malaria model (2017) (0)
- YS-201002500 sm miscellaneous information (2013) (0)
- The role of oxazoline and thiazole ring constraints in cyclic peptides of marine origin. (1997) (0)
- Homology model of the dengue 2 virus NS3 protease: Interactions with NS2B co-factor (1999) (0)
- Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles (2019) (0)
- Self-condensation of a thiazole-peptide bearing a 21-membered loop into a library of giant macrocycles with multiple orthogonal loops. (2006) (0)
- New cysteine derivatives with antiproliferative activity on melanoma cells. (2006) (0)
- CHARACTERIZING PEPTIDE ALPHA HELICES VIA COLD ION SPECTROSCOPY OF MODEL COMPOUNDS (2018) (0)
- A new C5a receptor antagonist inhibits monoarticular arthritis in the rat (2001) (0)
- MR1 is an endoplasmic reticulum-resident sensor of vitamin B metabolites (2016) (0)
- Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis (2017) (0)
- Synthesis, SAR, and Pharmacological Activities of a Series of Tyrosine-Derived Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (2000) (0)
- Specific for Riboflavin Metabolites Mucosal-Associated Invariant T Cells Antimycobacterial Effects of Mouse Functional Heterogeneity and (2015) (0)
- NMR structure of a short hydrophobic 11mer peptide in DMSO-d6/H2O (1:3) solution (2015) (0)
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